CN108567732A - Anti-aging composition containing dendrobium stem cell extract and preparation method thereof - Google Patents
Anti-aging composition containing dendrobium stem cell extract and preparation method thereof Download PDFInfo
- Publication number
- CN108567732A CN108567732A CN201810748164.0A CN201810748164A CN108567732A CN 108567732 A CN108567732 A CN 108567732A CN 201810748164 A CN201810748164 A CN 201810748164A CN 108567732 A CN108567732 A CN 108567732A
- Authority
- CN
- China
- Prior art keywords
- extract
- parts
- stem
- apolexis composition
- noble dendrobium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention discloses an anti-aging composition containing a dendrobium stem cell extract and a preparation method thereof, wherein the anti-aging composition comprises the following components in parts by weight: 1-3 parts of dendrobium stem cell extract, 5-15 parts of echinacea pallida extract and 5-15 parts of fructus evodiae extract. The echinacea pallida extract and the evodia rutaecarpa extract are compounded with the dendrobium stem cell extract to play a role in anti-aging synergistic synergy, under the synergistic effect of various extracts, the product can obviously improve the skin quality, improve the skin elasticity, improve the skin proliferation capacity and reduce the skin aging process, the effect is obviously higher than that of singly adding one or two extracts, and the extract is safe and non-irritant.
Description
Technical field
The present invention relates to cosmetic technical field, more particularly to a kind of anti-aging combination containing stem of noble dendrobium stem cell extract
Object and preparation method.
Background technology
Skin is the largest organ for being covered in human body surface, due to directly being contacted with external environment, aoxidized, dried,
The stimulation of various tension-causing factors such as ultraviolet light, is highly susceptible to injure.Meanwhile and because age, diet and living habit etc.
The influence of internal factor leads to the decline of skin function and hereditary grotesque, so that skin.
Wrinkle is skin aging as a result, it is the mark that bodily fuctions fall into a decline wrinkle occur, in general, if do not noted
Meaning maintenance, women start wrinkle after 28 years old and increase, and the age is bigger, and wrinkle is more.If malnutritive or psychological burden
Weight, wrinkle can also occur in advance.Wrinkle directly affects the appearance of face.But the tip of the brow is unawares climbed up.Wrinkle is beauty
The crow's feet at formidable enemy, especially canthus can most show the aging of a people.In a sense, the wrinkle of skin is strong to human body
There is no big harm for health and longevity.However, but being directly affected for beauty and human external image.The original formed about wrinkle
Cause can say that opinions vary so far, and the following origin cause of formation may be had by summing up：1, loss of moist increases：With advancing age, table
It flattens at skin and dermis, epidermis is thinning, surface area increases, and so that moisture of skin volatilization is accelerated, loses and increase；2, cuticula from
So moist factor content reduction causes skin hydration ability to decline：Since hydratability reduces, skin is difficult to keep normal moisture,
And skin is made to gradually appear fine wrinkles, and further increase and deepen with wrinkle, skin surface product is made to be continuously increased, moisture
It loses more serious, has dry skin at this time, wrinkle aggravates；3, with the growth at itself age and the influence of external environment, especially
It is ultraviolet irradiation, people's interior free yl increases, and most close free radical includes active oxygen radical (ROS) with Senescence
With active carbonyl compound (RCS), both the unstable molecule of high activity, ROS are easy to the reaction of other molecules, damage carefully
Born of the same parents, the by-product of human normal reaction, but external factor such as ultraviolet light, environmental toxin and pollution can accelerate its generation,
It crosslinks and reacts with structural proteins such as skin collagens, skin is caused wrinkle occur, and RCS is formed by ROS, concentration
Raising can accelerate the process of skin aging, series reaction can occur with structural proteins, enzyme and DNA and generate adduction
Object leads to the generation of all kinds of skin problems, is more prone to aging.
The stem of noble dendrobium is China's rare traditional Chinese medicine, is put into world's endangered protection plant, 76 kinds known to China, the whole world is about
There are 1500 kinds.《Sheng Nong's herbal classic》Deng record, the stem of noble dendrobium has eliminating impediment, lower gas, tonifying five zang organs consumptive disease, by skin heat symptoms caused by an exopathgen, Qiang Yin
And other effects, it has been investigated that the stem of noble dendrobium can significantly improve superoxide dismutase (SOD) level, lipid peroxide (LPO) is reduced, is adjusted
It is horizontal to save brain monoaminergic transmitters, inhibits similar monoamine oxidase (MAO), plays the role of anti-aging.It received in recent years
The dendrobium polysaccharide of concern also has the multiple efficacies such as significant immune-enhancing activity and anti-aging, radioresistance, such as Tiepi Fengdou
The brilliant, stem of noble dendrobium dissipates, peaceful, the beneficial intestines soup of clearing, noble dendrobium stem distillate, stem of noble dendrobium essence, yin-nourishing oral solution and stem of noble dendrobium piece etc..With dendrobium candidum processing
" maple bucket " or " earrings dendrobium " are referred to as " golden ear dendrobium ", " dendrobium ring ", " Jin Fengdou ", are in great demand in Southeast Asia and America and Europe.
Plant stem cell (plant stem cell) is undifferentiated cell, has very strong self-renewing and persistently divides
Split ability.Studies have shown that the skin care item containing stem cell can stimulate cell turnover, promote collagen secretion, using dry thin
The effect of born of the same parents is more rapidly more effective than general skin care item.Chinese patent CN 102670438B disclose a kind of anti-aging beauty-care shield
Skin product, containing plant stem cell active matter 0.01~3wt% of 0.001~3wt%, Dragosine carnosine, the plant is dry thin
Cytoactive object is PhytocelltecTMMalusDomestica apples stem cell, PhytocelltecTMSolarVitis grapes
Stem cell, Phy tocell te cTM Al pR ose rose leafs stem cell, Phy tocell te cTM Arga n nuts are dry
At least one of cell, RegenistemRiceAp red rice stem cells.The cosmetics and skincare product has improvement skin quality, improves skin
The effect of elasticity.
Currently, about stem of noble dendrobium stem cell extract in skin care item, there are no relevant report, therefore, the present invention selects
Stem of noble dendrobium stem cell extract is compounded with other extracts, works out the composition of anti-aging.
Invention content
The object of the present invention is to provide a kind of anti-apolexis composition containing stem of noble dendrobium stem cell extract and its preparations
Method, the preferable anti-senescence function of the anti-apolexis composition.
To achieve the above object, the technical solution used in the present invention：A kind of anti-apolexis composition, including following parts by weight
Ingredient：1~3 part of stem of noble dendrobium stem cell extract, 5~15 parts of echinacea pallida extract, 5~15 parts of evodia rutaecarpa berry extract.
Single extract is usually used in the prior art and carries out anti-aging, however its effect is ideal not to the utmost, the application hair
A person of good sense has found by numerous studies, and stem of noble dendrobium stem cell extract, echinacea pallida extract, evodia rutaecarpa berry extract are answered
Match, anti-aging effects are significantly better than independent extract.
Preferably, anti-apolexis composition includes the ingredient of following parts by weight：It is 1.5~3 parts of stem of noble dendrobium stem cell extract, pale
5~10 parts of echinacea extract, 10~15 parts of evodia rutaecarpa berry extract.
In the present composition, the proportioning of component can influence the effect of composition, the study found that in the preferred weight
In part range, the antioxidant effect of the present composition is more preferably.
Preferably, anti-apolexis composition includes the ingredient of following parts by weight：2 parts of stem of noble dendrobium stem cell extract, echinacea
10 parts of chrysanthemum extract, 12 parts of evodia rutaecarpa berry extract.Applicant has been surprisingly found that in many experiments, in the specific weight proportion
Under, the anti-aging effects of the present composition reach best.
Preferably, anti-apolexis composition includes the ingredient of following parts by weight：3 parts of stem of noble dendrobium stem cell extract, echinacea
5 parts of chrysanthemum extract, 10 parts of evodia rutaecarpa berry extract.
Preferably, the stem of noble dendrobium stem cell extract and echinacea pallida extract mass ratio are 1:5.Applicant is through excessive
Amount experiment, obtains this two kinds of extract quality ratios 1:In the case of 5 proportionings, senile-resistant efficacy is best.
Preferably, anti-apolexis composition further includes moisturizer, emulsifier, preservative, thickener, water.
Preferably, the moisturizer is at least one of glycerine, trehalose, butanediol, and the thickener is card wave
At least one of nurse, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, xanthans；The emulsifier
For at least one of the combination of stearine, stereth -2 and stereth -21, Phosphoric acid monohexadecyl ester potassium；Institute
It is at least one of Phenoxyethanol and potassium sorbate to state preservative.
A kind of preparation method of anti-apolexis composition, the preparation method are accurately to claim each component raw material by weight ratio
Amount is sufficiently mixed and is stirred evenly to get to the composition.
Preferably, the dosage form of the anti-apolexis composition is aqua, creme, finish, washing lotion or emulsion.
A kind of anti-aging skin care product, including anti-apolexis composition described in any one of the above embodiments.
Anti-apolexis composition main component and effect used in the present invention are as follows：
The stem of noble dendrobium：It has been investigated that the stem of noble dendrobium can significantly improve superoxide dismutase (SOD) level, lipid peroxide is reduced
(LPO), it is horizontal that brain monoaminergic transmitters are adjusted, inhibits similar monoamine oxidase (MAO), plays the role of anti-aging.Closely
A little dendrobium polysaccharide being concerned in year also have the multiple efficacies such as significant immune-enhancing activity and anti-aging, radioresistance, such as
Capsule Dendrobii, the stem of noble dendrobium dissipate, clearing is peaceful, beneficial intestines soup, noble dendrobium stem distillate, stem of noble dendrobium essence, yin-nourishing oral solution and stem of noble dendrobium piece etc..With dendrobium candidum
" the maple bucket " or " earrings dendrobium " of processing is referred to as " golden ear dendrobium ", " dendrobium ring ", " Jin Fengdou ", is in great demand in Southeast Asia
And it is American-European.
It is raw material that the present invention, which selects the stem cell of the stem of noble dendrobium, and plant stem cell includes about development of plants and to grow all
Formula possesses the cell of eternal life power, is the root (origin) of plant life power.Plant stem cell, which is present in, to be referred to as point
In the special tectonic of raw tissue, there is very surprising power of regeneration.These allow plant constantly to be grown between centuries,
And generate completely new organ.Plant stem cell is the primary raw material and source of skin progenitor cell metabolism, can quickly be activated not
Dormancy stem cell promotes stem cell self-regeneration update, the first viability of reduction epidermal stem cells to keep Skin Cell newborn in a steady stream, from
And reach promotion, firm skin, desalinate the anti-aging effects of wrinkle, while can be easier to be absorbed by the skin the nutrition of plant at
Point, accelerate human metabolism.
Echinacea：Echinacea purpurea is Echinacea plant, is herbaceos perennial, and Echinacea purpurea also has very high
Medical value is to be currently used primarily in treatment flu, cough, a kind of herbal medicine of upper respiratory tract infection, and applicant passes through
Numerous studies find that the echinacea pallida extract in Echinacea purpurea can be applied in cosmetics, have anti-aging function.
Evodia rutaecarpa：Usually divide several kinds such as great Hua evodia rutaecarpas, middle colored evodia rutaecarpa and little Hua evodia rutaecarpas.Evodia rutaecarpa and its change
Kind is conventional Chinese medicine close to mellow fruit, and the hot bitter of property is cold, has heat dissipation to relieve pain, the work(of stopping nausea and vomiting by lowering the adverse flow of QI, for treating liver
The diseases such as headache or stomach wrist pain caused by the stomach cold of insufficiency type, cloudy turbid superinverse.
It has been observed that evodia rutaecarpa berry extract has effects that tranquil skin, stimulation of the environmental pollution to skin can be reduced, is prolonged
Slow aging effect.
The beneficial effects of the present invention are：Stem of noble dendrobium stem cell extract has powerful inoxidizability and activity of fighting against senium,
The concentration of the SOD in human plasma can be increased, the ability of oxygen radical is resisted in enhancing, but also can enhance collagen
Concentration fundamentally the problem of the aging of prevention face, while adding with whitening, skin-active, can reduce the pale pine of oxygen radical
Fruit chrysanthemum extract, evodia rutaecarpa berry extract are compounded with stem of noble dendrobium stem cell extract, the synergy synergistic effect of anti-wrinkle are played, more
Under kind extract synergistic effect, product can be obviously improved skin quality, improve skin elasticity, improve the Reproductive activity of skin and reduce skin
The ager process that declines of skin, it is with obvious effects to add one of which or two kinds of extracts higher than independent and safe and non-stimulating.
Specific implementation mode
Each raw material involved by following embodiment is the commercially available universal product unless otherwise instructed.
The preparation method of stem of noble dendrobium stem cell extract of the present invention is：1) good stem of noble dendrobium leaf is chosen, and is cleaned
Disinfection, and it is cut into last shape, manufacture callus；2) callus is inoculated in solid medium and carries out Fiber differentiation, cut more
For the regeneration site of injured tissue to carry out squamous subculture, the product after culture, which carries out being transferred to fluid nutrient medium, is enlarged culture,
It transfers to bioreactor and carries out large-scale culture, until obtaining the stem of noble dendrobium stem cell suspension of saturation；3) it is obtained 2) middle
Stem of noble dendrobium stem cell suspension is filtered with 1 μm of filter, removes culture medium, harvest the cell of retention；And cell is put into -80 DEG C
Superfreeze 2 hours then takes out defrosting 30 minutes, repeats aforesaid operations 5 times, after last time thaw at RT, with ultrasound
Wave is crushed instrument smudge cells and collects filtrate after filter filtering, in being concentrated in rotating vacuum evaporator, you can obtains the stem of noble dendrobium
Stem cell extract.
The making of above-mentioned callus and cultural method and the squamous subculture used expand culture, extensive training
Foster mode is all made of method well known in the art, is not described in detail herein to obtain the stem cell of saturation.
Embodiment 1
Anti-apolexis composition of the present invention includes the ingredient of following parts by weight：It is 2 parts of stem of noble dendrobium stem cell extract, grey
White 10 parts of echinacea extract, 12 parts of evodia rutaecarpa berry extract.
Embodiment 2
Anti-apolexis composition of the present invention includes the ingredient of following parts by weight：It is 3 parts of stem of noble dendrobium stem cell extract, grey
White 5 parts of echinacea extract, 10 parts of evodia rutaecarpa berry extract.
Embodiment 3
Anti-apolexis composition of the present invention includes the ingredient of following parts by weight：It is 1 part of stem of noble dendrobium stem cell extract, grey
White 15 parts of echinacea extract, 15 parts of evodia rutaecarpa berry extract.
Embodiment 4
Anti-apolexis composition of the present invention includes the ingredient of following parts by weight：It is 1 part of stem of noble dendrobium stem cell extract, grey
White 15 parts of echinacea extract, 5 parts of evodia rutaecarpa berry extract.
Embodiment 5
Anti-apolexis composition of the present invention includes the ingredient of following parts by weight：1.5 parts of stem of noble dendrobium stem cell extract,
8 parts of echinacea pallida extract, 15 parts of evodia rutaecarpa berry extract.
Embodiment 6
Anti-apolexis composition of the present invention includes the ingredient of following parts by weight：It is 3 parts of stem of noble dendrobium stem cell extract, grey
White 5 parts of echinacea extract, 5 parts of evodia rutaecarpa berry extract.
Comparative example 1
The anti-apolexis composition formula of comparative example 1 is：2 parts by weight of stem of noble dendrobium stem cell extract, echinacea pallida extract
10 parts by weight.
Comparative example 2
The anti-apolexis composition formula of comparative example 2 is：2 parts by weight of stem of noble dendrobium stem cell extract, evodia rutaecarpa berry extract 12
Parts by weight.
Comparative example 3
The anti-apolexis composition formula of comparative example 3 is：10 parts by weight of echinacea pallida extract, evodia rutaecarpa berry extract 12
Parts by weight.
Comparative example 4
The anti-apolexis composition formula of comparative example 4 is：5 parts by weight of stem of noble dendrobium stem cell extract, echinacea pallida extract 4
Parts by weight, 12 parts by weight of evodia rutaecarpa berry extract.
Comparative example 5
The anti-apolexis composition formula of comparative example 5 is：2 parts by weight of stem of noble dendrobium stem cell extract, echinacea pallida extract 2
Parts by weight, 16 parts by weight of evodia rutaecarpa berry extract.
The preparation method of 1~5 anti-apolexis composition of Examples 1 to 6 and comparative example：Each component raw material is pressed into above-mentioned weight
Proportion speed weighs, and is sufficiently mixed and stirs evenly, you can.
Effect example 1
The senile-resistant efficacy evaluation test of 1~6 anti-apolexis composition of the embodiment of the present invention
By Examples 1 to 6, the composition of comparative example 1~5 sets 3 respectively with DPPH (final concentration of 100M) hybrid reaction
A repeating hole, while the blank control without extracting solution and vitamin E positive control are set, 30 DEG C are reacted 1 hour, and microplate reader is surveyed
Determine OD values, antioxygen rate is calculated in Detection wavelength 515nm, and the results are shown in Table 2.
Antioxygen rate (%)=(1- experimental ports OD515nm/ blank well OD515nm) × 100%；
1 sample Antioxidtive Activities in Vitro of table
As can be seen from Table 1, stem of noble dendrobium stem cell extract, echinacea pallida extract, evodia rutaecarpa berry extract three are equal
With senile-resistant efficacy, and to compound its senile-resistant efficacy best by three.Stem of noble dendrobium stem cell extract, pale pine in comparative example 4,5
Fruit chrysanthemum extract, the parts by weight of evodia rutaecarpa berry extract composition are not complete within the scope of the present invention, it can be seen that its effect is not so good as
The present invention, it is seen that three kinds of stem of noble dendrobium stem cell extract, echinacea pallida extract, evodia rutaecarpa berry extract extracts are by the present invention
The parts by weight of composition together, keeps the antioxidant effect of skin care item of the present invention more preferable, also, as shown in Table 1, when the stem of noble dendrobium is dry thin
The antioxidant effect of skin care item of the present invention when 2 parts of born of the same parents' extract, 10 parts of echinacea pallida extract, 12 parts of evodia rutaecarpa berry extract
Preferably, this is that applicant has been surprisingly found that.
Effect example 2
The composition of the present invention has the effect of good anti-aging.This effect example investigated stem of noble dendrobium stem cell extract with it is grey
Influence of the mass ratio of white echinacea extract to present composition anti-aging effects.In order to investigate the influence, we according to
The method of embodiment 1 is prepared for different compositions.Each experimental group composition is made of following components in parts by weight, and the stem of noble dendrobium is dry
1~3 part of cell extract, 5~15 parts of echinacea pallida extract, 5~15 parts of evodia rutaecarpa berry extract；Wherein stem of noble dendrobium stem cell
The mass ratio of extract and echinacea pallida extract is as shown in table 2 below.
Table 2
1~4 senile-resistant efficacy evaluation test method of experimental group is identical as effect example 1, is not described herein, obtains table 3；
Table 3
| Experimental group | Concentration (μ g/mL) | Antioxygen rate (%) |
| Experimental group 1 | 100 | 96.67 |
| Experimental group 2 | 100 | 94.17 |
| Experimental group 3 | 100 | 91.68 |
| Experimental group 4 | 100 | 93.68 |
As seen from Table 3, the mass ratio of stem of noble dendrobium stem cell extract and echinacea pallida extract is 1:It is anti-ageing when 5
Old best results.
Guinea pig skin stimulation test
0.5g Examples 1 to 6 anti-apolexis compositions are respectively taken, being diluted to 100g using deionized water is configured to given the test agent.
Given the test agent using skin irritation test method (《Cosmetics health specification》2007 editions toxicology test methods) it is tested.
Experimental animal：Cavy weight 250g~300g.
Experimental result：Through 14 days Skin Irritation Tests, stimulate the reaction is had no.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than is protected to the present invention
The limitation of range is protected, although being explained in detail to the present invention with reference to preferred embodiment, those skilled in the art should
Understand, technical scheme of the present invention can be modified or replaced equivalently, without departing from the essence of technical solution of the present invention
And range.
Claims (10)
1. a kind of anti-apolexis composition, which is characterized in that include the ingredient of following parts by weight：Stem of noble dendrobium stem cell extract 1~3
Part, 5~15 parts of echinacea pallida extract, 5~15 parts of evodia rutaecarpa berry extract.
2. anti-apolexis composition according to claim 1, which is characterized in that include the ingredient of following parts by weight：The stem of noble dendrobium is dry
1.5~3 parts of cell extract, 5~10 parts of echinacea pallida extract, 10~15 parts of evodia rutaecarpa berry extract.
3. anti-apolexis composition according to claim 1, which is characterized in that include the ingredient of following parts by weight：The stem of noble dendrobium is dry
2 parts of cell extract, 10 parts of echinacea pallida extract, 12 parts of evodia rutaecarpa berry extract.
4. anti-apolexis composition according to claim 1, which is characterized in that include the ingredient of following parts by weight：The stem of noble dendrobium is dry
3 parts of cell extract, 5 parts of echinacea pallida extract, 10 parts of evodia rutaecarpa berry extract.
5. anti-apolexis composition according to claim 1, which is characterized in that the stem of noble dendrobium stem cell extract and pale pine
The mass ratio of fruit chrysanthemum extract is 1:5.
6. anti-apolexis composition according to claim 1, which is characterized in that further include moisturizer, emulsifier, preservative,
Thickener, deionized water.
7. anti-apolexis composition according to claim 6, which is characterized in that the moisturizer is glycerine, trehalose, fourth
At least one of glycol, the thickener are carbomer, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymerics
At least one of object, xanthans；The emulsifier is stearine, stereth -2 and stereth -21
At least one of in combination, Phosphoric acid monohexadecyl ester potassium；The preservative be in potassium sorbate and Phenoxyethanol at least
It is a kind of.
8. a kind of preparation method of anti-apolexis composition as described in any one in claim 1-5, which is characterized in that the preparation
Method is that each component raw material precise by weight ratio is sufficiently mixed and is stirred evenly and combined to get to the anti-aging
Object.
9. anti-apolexis composition according to claim 6, which is characterized in that the dosage form of the anti-apolexis composition is water
Agent, creme, finish, washing lotion or emulsion.
10. a kind of anti-aging skin care product, which is characterized in that including anti-apolexis composition according to any one of claims 1 to 5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810748164.0A CN108567732A (en) | 2018-07-09 | 2018-07-09 | Anti-aging composition containing dendrobium stem cell extract and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810748164.0A CN108567732A (en) | 2018-07-09 | 2018-07-09 | Anti-aging composition containing dendrobium stem cell extract and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108567732A true CN108567732A (en) | 2018-09-25 |
Family
ID=63572391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810748164.0A Withdrawn CN108567732A (en) | 2018-07-09 | 2018-07-09 | Anti-aging composition containing dendrobium stem cell extract and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108567732A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110200842A (en) * | 2019-05-14 | 2019-09-06 | 广州辰美化妆品有限公司 | Skin-care product additive |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748343A (en) * | 2016-02-25 | 2016-07-13 | 广州市科玮生物技术有限公司 | Natural plant extract composition and application thereof in cosmetics |
-
2018
- 2018-07-09 CN CN201810748164.0A patent/CN108567732A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748343A (en) * | 2016-02-25 | 2016-07-13 | 广州市科玮生物技术有限公司 | Natural plant extract composition and application thereof in cosmetics |
Non-Patent Citations (1)
| Title |
|---|
| 王建新等: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110200842A (en) * | 2019-05-14 | 2019-09-06 | 广州辰美化妆品有限公司 | Skin-care product additive |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104644523B (en) | A kind of medical bio smoothing wrinkle suppression spot dressing and preparation method thereof | |
| KR101839013B1 (en) | Cosmetic composition containing SARGASSUM FULVELLUM extract, CODIUM FRAGILE extract and UNDARIA PINNATIFIDA extract | |
| KR102113645B1 (en) | A cosmetic composition for preventing hair loss and promoting hair growth containing spicule powder and natural extract | |
| KR101816725B1 (en) | Manufacturing method for fermented extracts and cosmetic composition comprising fermented extracts | |
| CN111265441A (en) | Composition capable of enhancing skin night repair and regeneration capacity and application thereof | |
| CN105726439A (en) | Cordyceps cicadae whitening and moisturizing cosmeceutical and preparing method thereof | |
| CN109381390A (en) | A kind of sodium hyaluronate skin lightening Face-protecting mask and preparation method thereof | |
| CN113786378A (en) | Toning lotion composition with effects of improving skin color and brightening skin and preparation method thereof | |
| KR101985381B1 (en) | Cosmetic composition for exfoliating skin keratin comprising fruit fermentation complex made by fermenting grape, orange, apple, lemon and lime | |
| CN108635326A (en) | Anti-aging and wrinkle-removing composition containing dendrobium stem cell extract and application thereof | |
| CN107982200A (en) | A kind of anti-wrinkle skin care item containing Chinese wolfberry fruit dry cell extract and preparation method thereof | |
| KR101841118B1 (en) | Composition for skin external application comprising extract of scenedesmus sp. | |
| KR102029546B1 (en) | Anti-aging and anti-allergic cosmetic compositon comprising the extract of the flower, root, callus and seed of Hibiscus syriacus L. as an active ingredient and preparation method of the same | |
| CN108567732A (en) | Anti-aging composition containing dendrobium stem cell extract and preparation method thereof | |
| KR101769755B1 (en) | A leuconostoc mesenteroides gfc 160704, cosmetic composition including the leuconostoc mesenteroides gfc 160704 or its culture fluid, and manufacturing method of the cosmetic composition | |
| CN108721202A (en) | A kind of roselle stem cell freeze-dried powder eye cream and preparation method thereof | |
| KR101803757B1 (en) | Cosmetic composition containing natural complex fermented extracts | |
| CN107961209A (en) | A kind of skin care item of whitening anti-aging and preparation method thereof | |
| KR101662805B1 (en) | extract of rice bran reinforced vitamin and cosmetic composition and manufacturing method thereof | |
| CN108635327A (en) | Dendrobium stem cell extract anti-aging composition and cosmetic containing composition | |
| KR20210144725A (en) | Anti-aging, antioxidant, anti-inflammatory and whitening agents, and cosmetics | |
| KR101872353B1 (en) | Cosmetic composition comprising the very high-pressure extract of narcissus tazetta bulb fermentation | |
| CN108635325A (en) | Dendrobium stem cell extract anti-aging composition and cosmetic containing composition | |
| KR102002891B1 (en) | Cosmetic compositions comprising extracts of daedaleopsis tricolor and fermentation material by mycelium of daedaleopsis tricolor | |
| KR102182927B1 (en) | Cosmetic composition comprising extracts of fermented oenanthe javanica d.c using mycelium of cauliflower mushroom for anti-oxidation, anti-wrinkle, improving skin elasticity and skin whitening |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180925 |
|
| WW01 | Invention patent application withdrawn after publication |