CN109310668B - 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂 - Google Patents

毒蕈碱型乙酰胆碱受体m4的正向别构调节剂 Download PDF

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CN109310668B
CN109310668B CN201780036134.0A CN201780036134A CN109310668B CN 109310668 B CN109310668 B CN 109310668B CN 201780036134 A CN201780036134 A CN 201780036134A CN 109310668 B CN109310668 B CN 109310668B
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thieno
methyl
pyridazin
dimethylpyrimido
amino
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CN109310668A (zh
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C·W·林斯利
P·J·康恩
D·W·恩格尔斯
S·博林杰
J·C·塔尔
P·斯皮林
J·L·恩格尔斯
M·郎
T·M·布里奇斯
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Vanderbilt University
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
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  • Control Of El Displays (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201780036134.0A 2016-06-22 2017-06-22 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂 Active CN109310668B (zh)

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US201662353447P 2016-06-22 2016-06-22
US62/353,447 2016-06-22
US201662418638P 2016-11-07 2016-11-07
US62/418,638 2016-11-07
US201762471281P 2017-03-14 2017-03-14
US62/471,281 2017-03-14
PCT/US2017/038711 WO2017223290A1 (en) 2016-06-22 2017-06-22 Positive allosteric modulators of the muscarinic acetylcholine receptor m4

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CN202310019545.6A Pending CN116178391A (zh) 2016-06-22 2017-06-22 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂

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EP (2) EP4186910A1 (https=)
JP (1) JP7038414B2 (https=)
KR (1) KR102474326B1 (https=)
CN (2) CN109310668B (https=)
AU (1) AU2017281228B2 (https=)
BR (1) BR112018003417B1 (https=)
CL (1) CL2018003669A1 (https=)
CO (1) CO2018013600A2 (https=)
CR (1) CR20180598A (https=)
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DO (1) DOP2018000263A (https=)
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