CN109310518B - 形成用于视网膜下递送治疗剂的进入泡的装置和方法 - Google Patents

形成用于视网膜下递送治疗剂的进入泡的装置和方法 Download PDF

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Publication number
CN109310518B
CN109310518B CN201780037447.8A CN201780037447A CN109310518B CN 109310518 B CN109310518 B CN 109310518B CN 201780037447 A CN201780037447 A CN 201780037447A CN 109310518 B CN109310518 B CN 109310518B
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China
Prior art keywords
needle
flexible
fluid
syringe
cannula
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CN201780037447.8A
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Chinese (zh)
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CN109310518A (zh
Inventor
D·W·普莱斯
B·J·奥伯基尔彻
D·J·普伦格
G·金
T·E·梅耶
B·L·科
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Genentech Inc
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Orbit Biomedical Ltd
Gyroscope Therapeutics Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3403—Needle locating or guiding means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/427—Locating point where body is to be pierced, e.g. vein location means using ultrasonic waves, injection site templates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3403—Needle locating or guiding means
    • A61B2017/3405—Needle locating or guiding means using mechanical guide means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201780037447.8A 2016-06-17 2017-06-14 形成用于视网膜下递送治疗剂的进入泡的装置和方法 Active CN109310518B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662351611P 2016-06-17 2016-06-17
US62/351,611 2016-06-17
US15/609,386 US10646374B2 (en) 2016-06-17 2017-05-31 Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US15/609,386 2017-05-31
PCT/US2017/037361 WO2017218610A1 (en) 2016-06-17 2017-06-14 Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent

Publications (2)

Publication Number Publication Date
CN109310518A CN109310518A (zh) 2019-02-05
CN109310518B true CN109310518B (zh) 2021-08-17

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US (1) US10646374B2 (enExample)
EP (1) EP3471670B8 (enExample)
JP (1) JP6755976B2 (enExample)
KR (1) KR102227429B1 (enExample)
CN (1) CN109310518B (enExample)
AU (1) AU2017285139B2 (enExample)
IL (1) IL263599B2 (enExample)
RU (1) RU2742971C2 (enExample)
SA (1) SA518400661B1 (enExample)
SG (1) SG11201810521WA (enExample)
WO (1) WO2017218610A1 (enExample)

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US10806629B2 (en) 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
US11000410B2 (en) 2016-06-17 2021-05-11 Gyroscope Therapeutics Limited Guide apparatus for tangential entry into suprachoroidal space
US11076984B2 (en) 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
EP3618784B1 (en) 2017-05-04 2022-03-02 Carl Zeiss Meditec Cataract Technology Inc. Devices for ocular surgery
CN112702982B (zh) 2018-06-05 2023-12-19 卡尔蔡司白内障医疗技术公司 眼科显微手术工具、系统和使用方法
WO2020160434A1 (en) 2019-02-01 2020-08-06 Carl Zeiss Meditec Cataract Technology Inc. Ophthalmic cutting instruments having integrated aspiration pump
CN113453738B (zh) * 2019-02-08 2023-11-21 追踪注射器有限责任公司 针传感器组件及其使用方法
US11759355B1 (en) * 2019-02-26 2023-09-19 Gyroscope Therapeutics Limited Method of delivering leading blebs and agent to subretinal space
CA3140788A1 (en) 2019-05-17 2020-11-26 Carl Zeiss Meditec Cataract Technology Inc. Ophthalmic cutting instruments having integrated aspiration pump
KR102931503B1 (ko) 2019-06-07 2026-02-27 칼 짜이스 메디텍 캐터랙트 테크놀로지 인크. 눈의 수정체 낭 내부로부터 렌즈 조직을 제거하기 위한 의료 디바이스
CN114945397B (zh) * 2019-09-11 2025-02-25 阿尔塔维兹有限责任公司 具有剂量指导的微体积注射器和使用方法
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IT202000009049A1 (it) * 2020-04-27 2021-10-27 Marco Codenotti Dispositivo per chirurugia vitreo-retinica
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WO2022136913A1 (en) 2020-12-22 2022-06-30 Gyroscope Therapeutics Limited Ocular cannula guide
EP4281025B1 (en) * 2021-01-25 2026-02-18 Alcon Inc. Apparatus for subretinal injection
AU2022356475A1 (en) * 2021-09-30 2024-02-22 Alcon Inc. Apparatus for subretinal injection
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KR20250052375A (ko) 2022-07-11 2025-04-18 제넨테크, 인크. 유리체 통과 망막하 주입기
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CN116509627B (zh) * 2023-04-23 2025-07-25 哈尔滨工业大学 一种耳科手术机器人内耳注射采样执行器
TW202529711A (zh) 2023-09-29 2025-08-01 美商建南德克公司 眼插管導引器、施用器及標記器械
TW202602405A (zh) 2024-03-27 2026-01-16 美商建南德克公司 用於視網膜下注射裝置的扭矩環

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CN1266373A (zh) * 1997-08-06 2000-09-13 法玛西雅和厄普约翰公司 自动输送装置及其操作方法
CN1678369A (zh) * 2002-07-04 2005-10-05 伊诺维奥公司 电穿孔装置和注射设备
US20060257835A1 (en) * 2005-05-13 2006-11-16 Wallaker Daniel M Endoscopy simulation system
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Also Published As

Publication number Publication date
IL263599B (en) 2022-10-01
EP3471670A1 (en) 2019-04-24
CN109310518A (zh) 2019-02-05
US20170360607A1 (en) 2017-12-21
SA518400661B1 (ar) 2022-09-19
RU2742971C2 (ru) 2021-02-12
WO2017218610A1 (en) 2017-12-21
IL263599B2 (en) 2023-02-01
RU2019101083A3 (enExample) 2020-08-27
CA3026284A1 (en) 2017-12-21
JP6755976B2 (ja) 2020-09-16
AU2017285139A1 (en) 2018-12-20
EP3471670B8 (en) 2020-11-11
EP3471670B1 (en) 2020-10-14
US10646374B2 (en) 2020-05-12
JP2019517888A (ja) 2019-06-27
AU2017285139B2 (en) 2020-12-24
IL263599A (en) 2019-01-31
KR102227429B1 (ko) 2021-03-15
SG11201810521WA (en) 2018-12-28
BR112018075965A2 (pt) 2019-04-02
RU2019101083A (ru) 2020-07-17
KR20190022646A (ko) 2019-03-06

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