CN109283279A - 通过高效液相色谱法分离测定雷替曲塞及其对映异构体的方法 - Google Patents
通过高效液相色谱法分离测定雷替曲塞及其对映异构体的方法 Download PDFInfo
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- CN109283279A CN109283279A CN201710600429.8A CN201710600429A CN109283279A CN 109283279 A CN109283279 A CN 109283279A CN 201710600429 A CN201710600429 A CN 201710600429A CN 109283279 A CN109283279 A CN 109283279A
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- raltitrexed
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- enantiomter
- alcohol
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
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- Analytical Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
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- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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Abstract
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CN201710600429.8A CN109283279B (zh) | 2017-07-21 | 2017-07-21 | 通过高效液相色谱法分离测定雷替曲塞及其对映异构体的方法 |
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CN201710600429.8A CN109283279B (zh) | 2017-07-21 | 2017-07-21 | 通过高效液相色谱法分离测定雷替曲塞及其对映异构体的方法 |
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CN109283279A true CN109283279A (zh) | 2019-01-29 |
CN109283279B CN109283279B (zh) | 2019-11-01 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110988179A (zh) * | 2019-12-18 | 2020-04-10 | 南京正济医药研究有限公司 | 一种盐酸雷尼替丁及其制药的纯度检测方法 |
CN111678998A (zh) * | 2020-04-30 | 2020-09-18 | 扬子江药业集团有限公司 | 一种雷替曲塞中对映异构体的分离检测方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090275605A1 (en) * | 2005-08-05 | 2009-11-05 | Cambridge Laboratories (Ireland) Limited | 3,11 b-cis-Dihydrotetrabenazine for the Treatment of a Proliferative Disease or an Inflammatory Disease |
US20100234435A1 (en) * | 2007-11-08 | 2010-09-16 | Bhattacharya Samit K | Cycloalkylamino acid derivatives |
US20110301195A1 (en) * | 2008-11-19 | 2011-12-08 | David Lauffer | Triazolothiadiazole inhibitor of c-met protein kinase |
US20130210846A1 (en) * | 2010-04-01 | 2013-08-15 | Bayer Intellectual Property Gmbh | Use of novel pan-cdk inhibitors for treating tumors |
-
2017
- 2017-07-21 CN CN201710600429.8A patent/CN109283279B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090275605A1 (en) * | 2005-08-05 | 2009-11-05 | Cambridge Laboratories (Ireland) Limited | 3,11 b-cis-Dihydrotetrabenazine for the Treatment of a Proliferative Disease or an Inflammatory Disease |
US20100234435A1 (en) * | 2007-11-08 | 2010-09-16 | Bhattacharya Samit K | Cycloalkylamino acid derivatives |
US20110301195A1 (en) * | 2008-11-19 | 2011-12-08 | David Lauffer | Triazolothiadiazole inhibitor of c-met protein kinase |
US20130210846A1 (en) * | 2010-04-01 | 2013-08-15 | Bayer Intellectual Property Gmbh | Use of novel pan-cdk inhibitors for treating tumors |
Non-Patent Citations (2)
Title |
---|
JINGJING HU等: "Determination of raltitrexed in human plasma by high performance liquid chromatography–electrospray ionization-mass spectrometry", 《JOURNAL OF CHROMATOGRAPHY B》 * |
居靖: "注射用雷替曲塞的稳定性试验研究", 《中国药房》 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110988179A (zh) * | 2019-12-18 | 2020-04-10 | 南京正济医药研究有限公司 | 一种盐酸雷尼替丁及其制药的纯度检测方法 |
CN111678998A (zh) * | 2020-04-30 | 2020-09-18 | 扬子江药业集团有限公司 | 一种雷替曲塞中对映异构体的分离检测方法 |
CN111678998B (zh) * | 2020-04-30 | 2021-11-09 | 扬子江药业集团有限公司 | 一种雷替曲塞中对映异构体的分离检测方法 |
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Inventor after: Cui Shuzhong Inventor after: Zhu Chunxia Inventor after: Tian Zhoushan Inventor after: Chai Yuzhu Inventor after: Xu Jianliang Inventor after: Chu Xueyuan Inventor after: Huang Diwen Inventor after: Wang Zubing Inventor after: Langong Sword Inventor after: Wang Huaping Inventor after: Xu Dan Inventor before: Chai Yuzhu Inventor before: Xu Jianliang Inventor before: Chu Xueyuan Inventor before: Wang Zubing Inventor before: Langong Sword Inventor before: Wang Huaping Inventor before: Xu Dan Inventor before: Zhu Chunxia Inventor before: Tian Zhoushan |
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