CN109248281A - A kind of Chinese medicine composition and preparation method thereof for treating fibroid - Google Patents

A kind of Chinese medicine composition and preparation method thereof for treating fibroid Download PDF

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CN109248281A
CN109248281A CN201811484223.4A CN201811484223A CN109248281A CN 109248281 A CN109248281 A CN 109248281A CN 201811484223 A CN201811484223 A CN 201811484223A CN 109248281 A CN109248281 A CN 109248281A
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chinese medicine
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李天基
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The present invention relates to a kind of Chinese medicine composition and preparation method thereof for treating fibroid, the raw material components of the Chinese medicine composition of the treatment fibroid include radix scrophulariae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, ramulus cinnamomi, Poria cocos, rhizoma cyperi, Radix Notoginseng, spina gleditsiae, honeysuckle, cordate houttuynia, dandelion, Prunella vulgaris, first pearl, leech, Eupolyphoge sinensis, costazia bone, nitre, raw oyster, edible tulip, edible tulip bulb, seaweed, thallus laminariae, rhizome of cyrtomium, cockscomb, adlay, semen plantaginis and Radix Glycyrrhizae.Each raw material are subjected to appropriate weight proportion, the Chinese medicine composition for having effects that easypro liver reason spleen, blood being adjusted to warm up palace, resolving hard lump, detumescence detoxification is finally prepared, treatment fibroid is had a good effect, overall clinical efficacy rate reaches 82%.Chinese medicine composition compatibility of the present invention is scientific, it is significant in efficacy, take effect rapidly, and have no toxic side effect.Preparation method is simple for Chinese medicine composition of the present invention, mild condition and stability is good, easy to spread.

Description

A kind of Chinese medicine composition and preparation method thereof for treating fibroid
Technical field
The invention belongs to technical field of Chinese medicine, and in particular to a kind of Chinese medicine composition for treating fibroid and its preparation Method.
Background technique
Fibroid be in female sex organ in one of the most common type benign tumour and human body the most common tumour it One, also known as fibromyoma, fibroma uteri.Since fibroid is mainly formed by Uterine Smooth Cell hyperplasia, wherein There is a small amount of fibrous connective tissue to exist as a kind of supporting tissue.The cause of disease in relation to fibroid is still not very clear so far, It may relate to the more complicated interaction between the cell mutation, sex hormone and tropic growth factors of normal muscle layer.Uterus Myomata mostly occurs with the women of childbearing age, is more common in 30-50 years old women, seldom sees puberty women with uterus muscle Atrophy or recession occur for tumor, postmenopausal uterine leiomyoma.The most non-evident sympton of fibroid, it is difficult to find, if treatment is not In time, the symptoms such as a variety of harm, such as infertile, miscarriage, induction gynaecological imflammation, secondary anemia are be easy to cause, or even have generation A possibility that malignant change.
Treatment method for fibroid mainly includes conservative therapy, drug therapy and operative treatment.Doctor trained in Western medicine mostly uses Operative treatment, but be not suitable for for operation and the women for thering is fertility to require to fearing.This disease of Chinese medicine conservative therapy has good Advantage, but lack has the Chinese medicine of definite curative effect currently on the market, therefore be badly in need of us and develop a kind of safety, curative effect reliably simultaneously And the rapid Chinese medicine preparation that works.
Summary of the invention
In order to solve the above problems existing in the present technology, the present invention provides it is a kind of it is significant in efficacy, take effect and rapidly control Treat fibroid Chinese medicine composition and preparation method thereof, it is described treatment fibroid Chinese medicine composition have relax liver reason spleen, The effect of adjusting blood to warm up palace, resolving hard lump, detumescence detoxification, has a good effect treatment fibroid.
The technical scheme adopted by the invention is as follows:
A kind of Chinese medicine composition for treating fibroid, raw material components include:
Radix scrophulariae 12-18 parts by weight, Radix Angelicae Sinensis 8-12 parts by weight, Rhizoma Chuanxiong 8-12 parts by weight, ramulus cinnamomi 12-18 parts by weight, Poria cocos 12- 18 parts by weight, rhizoma cyperi 12-18 parts by weight, Radix Notoginseng 5-7 parts by weight, spina gleditsiae 24-36 parts by weight, honeysuckle 12-18 parts by weight, fish Raw meat grass 24-36 parts by weight, dandelion 24-36 parts by weight, Prunella vulgaris 12-18 parts by weight, first pearl 5-15 parts by weight, leech 8-12 weight Measure part, Eupolyphoge sinensis 8-12 parts by weight, costazia bone 12-18 parts by weight, nitre 8-12 parts by weight, raw oyster 24-36 parts by weight, edible tulip 12-18 parts by weight, edible tulip bulb 12-18 parts by weight, seaweed 12-18 parts by weight, thallus laminariae 12-18 parts by weight, rhizome of cyrtomium 12-18 weight Part, cockscomb 12-18 parts by weight, adlay 24-36 parts by weight, semen plantaginis 12-18 parts by weight, Radix Glycyrrhizae 8-12 parts by weight.
The raw material components of Chinese medicine composition of the further preferably described treatment fibroid include:
15 parts by weight of radix scrophulariae, 10 parts by weight of Radix Angelicae Sinensis, 10 parts by weight of Rhizoma Chuanxiong, 15 parts by weight of ramulus cinnamomi, 15 parts by weight of Poria cocos, rhizoma cyperi 15 parts by weight, 6 parts by weight of Radix Notoginseng, 30 parts by weight of spina gleditsiae, 15 parts by weight of honeysuckle, 30 parts by weight of cordate houttuynia, 30 weight of dandelion Measure part, 15 parts by weight of Prunella vulgaris, 10 parts by weight of first pearl, 10 parts by weight of leech, 10 parts by weight of Eupolyphoge sinensis, 15 parts by weight of costazia bone, nitre 10 parts by weight of stone, 30 parts by weight of raw oyster, 15 parts by weight of edible tulip, 15 parts by weight of edible tulip bulb, 15 parts by weight of seaweed, 15 weight of thallus laminariae Measure part, 15 parts by weight of rhizome of cyrtomium, 15 parts by weight of cockscomb, 30 parts by weight of adlay, 15 parts by weight of semen plantaginis, 10 parts by weight of Radix Glycyrrhizae.
Further, the dosage form of described pharmaceutical composition is pill or paste.
The preparation method of the Chinese medicine composition of the treatment fibroid, comprising the following steps:
(1) each raw material cleaned, cleaned, dried, mixed thoroughly later with wine, obtain mixing liquor raw material;
(2) liquor raw material of mixing is subjected to mild fire frying, obtains raw material after wine toast;
(3) raw material nano after wine toast is crushed, raw material after being crushed;Bee is added in raw material after to the crushing Honey stirs evenly, and thin ball is made to get the Chinese medicine composition of the treatment fibroid is arrived.
Further, in step (1), the wine of selection is the white wine that Alcohol degree is 52%Vol-63%Vol;The raw material Mass ratio with alcohol is 10:(1-2).
Further, in step (3), the smashed partial size of raw material is 20-100nm.
Further, in step (3), honey is rape flower honey;The mass ratio of raw material and rape flower honey is after crushing (3-5):1;Every thin ball quality is 0.1g-0.3g.
Further, instructions of taking is that 2 times a day, each 9-12g takes medicine on an empty stomach sooner or later, warm water delivery service, after medication It feeds again within 60-90 minutes.
The preparation method of the Chinese medicine composition of the treatment fibroid, comprising the following steps:
(1) each raw material described above cleaned, cleaned, dried, soaked in water rear high fire and decoct, then turn to be cooked by slow fire It boils, filtrate is obtained by filtration;
(2) filtrate is condensed into cream, obtains the Chinese medicine composition of the treatment fibroid.
Further, in step (1), the mass ratio of raw material and water is 1:(2-4), soaking time 1-3h;High fire decocts Time is 3-7min;Being cooked by slow fire the time is 40-140min;Filtering uses 300-800 mesh filter screen.
Further, in step (2), temperature is 35-45 DEG C when concentration.
Further, instructions of taking is that 2 times a day, each 120-150ml takes again after sooner or later on an empty stomach warming ointment, It could feed within 60-90 minutes after medication.
It underdraws below to effect caused by raw material in the present invention.
Radix scrophulariae, it is bitter, sweet, salty, it is cold in nature;Return lung, stomach, kidney channel.Effect: clearing heat and cooling blood, detoxicating and resolving a mass, enriching yin are raw Saliva.It joins the army point for heat, fever aggravated at night, blood-head macular eruption, abscess of throat, carbuncle sore tumefacting virus, dry constipation of intestines.
Radix Angelicae Sinensis, it is sweet in flavor, pungent, it is warm-natured;Return liver, the heart, the spleen channel.Effect: promoting blood circulation and stopping pain, tonifying blood and regulating menstruation, relax bowel and defecation.With In dizziness due to deficiency of blood, irregular menstruation, menostasis, dysmenorrhea, sallow complexion, asthenia cold abdominalgia, traumatic injury, rheumatic arthralgia, ulcer sores, intestines Dry constipation.
Rhizoma Chuanxiong, acrid flavour are warm-natured;Return liver, gallbladder, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.Not for menstruation Tune, hypochondriac pain, thoracic obstruction, sore swell and ache curative, traumatic injury, headache, rheumatic arthralgia.
Ramulus cinnamomi, it is acrid flavour, sweet, it is warm-natured;Return heart, lung, bladder meridian.Effect: inducing sweat and dispelling exogenous evils, Wen Jing activate yang.For chill Exterior syndrome, wind-cold-dampness arthralgia, arthralgia, oedema, phlegm retention, the stagnant menostasis of thoracic obstruction, palpitaition, the stasis of blood, dysmenorrhea, Disorder lump in the abdomen, epigastric pain.
Poria cocos, it is sweet in flavor, light, it is mild-natured;Return heart, spleen, kidney channel.Effect: clearing damp and promoting diuresis, invigorating the spleen are calmed the nerves.For oedema, Diarrhea, difficult urination, phlegm retention, palpitaition, insomnia.
Rhizoma cyperi, acrid flavour, slight bitter, micro-sweet are mild-natured;Return liver, tri-jiao channel.Effect: dispersing stagnated hepatoqi, menstruction regulating and pain relieving.For Pain over the hypochondriac region, abdominal distention, hernia pain, irregular menstruation, swollen breasts.
Radix Notoginseng, sweet in flavor, slight bitter are warm-natured;Return heart, liver, the spleen channel.Effect: removing blood stasis and hemostasis, swelling and pain relieving.For inside and outside Bleeding, traumatic injury, blood stasis and swelling pain.
Spina gleditsiae, acrid flavour are warm-natured;Return liver, stomach meridian.Effect: detumescence and apocenosis searches wind detoxification.For ulcer sores, scrofula The card such as scrofula subcutaneous nodule, and wind desinsection is controlled, the card such as leprosy, psoriasis can be treated.
Honeysuckle, it is sweet in flavor, it is cold in nature;Return lung, the heart, stomach, large intestine channel.Effect: clearing heat and detoxicating, dispelling wind and heat from the body.For outer Feel wind-heat, warm disease heating, carbuncle swells sore, abscess of throat, heat toxin dysentery.
Cordate houttuynia, acrid flavour, cold nature;It is distributed in lung channel.Effect: clearing heat and detoxicating, the carbuncle that disappears apocenosis, promoting diuresis for stranguria.For lung Carbuncle chest carbuncle, cough with lung heat, pathopyretic ulcer, damp-heat gonorrhoea.
Dandelion, it is bitter, sweet, it is cold in nature;Return liver, stomach meridian.Effect: clearing heat and detoxicating, dampness removing.It is yellow for pathopyretic ulcer Subcutaneous ulcer, heat gonorrhea, red eye, swell pain.
Prunella vulgaris, acrid flavour, hardship are cold in nature;Return liver, gallbladder channel.Effect: clearing away the liver-fire, Disperse hepatic depression, Pinggan Yang.For hot eyes Swelling and pain, eyeball night pain, scrofula goiter, dizziness and headache.
First pearl, taste is salty, cold;Return liver, stomach meridian.Effect: carbuncle of bursting of reducing swelling, it is active to search wind, newborn under promoting menstruation.Control ulcer Sore swells, wind-cold-dampness arthralgia, amenorrhea, alactation, hematochezia.
Leech, taste is salty, bitter, mild-natured;Return liver warp.Effect: dissipating blood stasis with potent drugs.For menostasis , Disorder lump in the abdomen, traumatic injury.
Eupolyphoge sinensis, taste is salty, cold in nature;Return liver warp.Effect: dissipating blood stasis with potent drugs, reunion of fractured tendons and bones.For menostasis , Disorder lump in the abdomen, the postpartum stasis of blood Resistance, fracture are grieved.
Costazia bone, taste is salty, cold in nature;It is distributed in lung channel.Effect: clearing lung and eliminating phlegm, resolving hard lump.For phlegm-heat cough, scrofula Tuberculosis.
Nitre, taste is salty, bitter, cold in nature;Return lung, spleen, kidney, small intestine, three burnt, large intestine channels.Effect: purgating heat and bowels is moisturized Softening hard masses, detumescence of relieving inflammation or internal heat.For real heat constipation, dry feces, stagnate abdominal pain, acute appendicitis swelling and pain;Acute mastitis, hemorrhoid gall are controlled outside.
Raw oyster, taste is salty, puckery, cold nature;Return liver and kidney channel.Effect: calming the liver, astringency inducing, resolving hard lump. Cure mainly night sweat, spontaneous perspiration, spermatorrhea, diarrhea, metrorrhagia and metrostaxis, leukorrhagia, frightened epilepsy, dizziness, scrofula subcutaneous nodule, hernia lump in the abdomen, pained, carbuncle sore tumefacting virus, insomnia Deng.
Edible tulip, sweet in flavor, micro-pungent are cold in nature;Return liver, stomach, lung channel.Effect: clearing heat and detoxicating, dispersing swelling and dissipating binds.For carbuncle Subcutaneous ulcer malignant sore, scrofula tuberculosis, pharyngalgia sore throat, snake, insect bite.
Edible tulip bulb, it is sweet in flavor, it is cold in nature;Return lung, Liver Channel.Effect: detoxicating and resolving a mass, promoting circulation of blood stagnation resolvation.Control abscess of throat, scrofula Scrofula, ulcer, sore swells, postpartum stasis.
Seaweed, it is bitter, salty, it is cold in nature;Return lung, stomach, kidney channel.Effect: resolving hard lump, dissolving phlegm, Li Shui.For goiter, Scrofula, oedema, tinea pedis, testiclar gall.
Thallus laminariae, taste is salty, cold in nature;Return liver, stomach, kidney channel.Effect: resolving hard lump, dissolving phlegm, Li Shui.For goiter, scrofula Scrofula, oedema, tinea pedis, testiclar gall.
Rhizome of cyrtomium, bitter, cold nature;Return liver, lung channel.Effect: desinsection, hemostasis are clearing heat and detoxicating.For abdominal pain due to enterositosis, Hematemesis and epistaxis, metrostaxis, anemopyretic cold warm macula, mumps sore throat.
Cockscomb, it is sweet in flavor, puckery, it is cool in nature;Return liver, large intestine channel.Effect: cool blood, hemostasis.Control blood under anal fistula, Chi Baixia Dysentery is spitted blood, hemoptysis, blood strangury, women's metrorrhagia, leukorrhea with reddish discharge.
Adlay, sweet in flavor, light, cold nature;Returns spleen, stomach, lung channel.Effect: clearing damp and promoting diuresis, invigorating the spleen to arrest diarrhea, clearing damp eliminating impediment, Clearing away heat and eliminating pus.For difficult urination, oedema, tinea pedis, splenasthenic diarrhea, rheumatic arthralgia, Spasm of the tendons, pulmonary abscess, acute appendicitis.
Semen plantaginis, it is sweet in flavor, it is cold in nature;Return kidney, liver, lung channel.Effect: promoting diuresis for stranguria, dampness removing antidiarrheal are clear liver and improved vision, clearly Lung resolving sputum.For difficult urination, oedema, stranguria, summer heat damp diarrhea, the hot hot eyes of liver, cough with lung heat.
Radix Glycyrrhizae, it is sweet in flavor, it is mild-natured;Return heart, spleen, lung, stomach meridian.Effect: invigorating the spleen and benefiting qi, and moistening lung to arrest cough is clearing heat and detoxicating, delays Solution analgesic, mitigates pharmacological property.For weakness of the spleen and the stomach, shortness of breath and fatigue, palpitation and severe palpitation, cough phlegm is few, pathopyretic ulcer, medicine food poisoning, gastral cavity Abdomen shoot, four limbs contraction pain.
The invention has the benefit that
It is of the present invention treatment fibroid Chinese medicine composition, with radix scrophulariae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, ramulus cinnamomi, Poria cocos, rhizoma cyperi, The easypro liver of Radix Notoginseng manages spleen, and blood is adjusted to warm up palace;With spina gleditsiae, honeysuckle, cordate houttuynia, dandelion, Prunella vulgaris, detoxification of reducing swelling;With first pearl, water Leech, Eupolyphoge sinensis, costazia bone, nitre, raw oyster, edible tulip, edible tulip bulb, seaweed, thallus laminariae, resolving hard lump;With rhizome of cyrtomium, cockscomb priming Enter palace;With adlay, the smooth dredging water passages of semen plantaginis;Detoxified with Radix Glycyrrhizae, and coordinating the drug actions of a prescription, treatment uterine fibroid disease has definite curative effect. The Chinese medicine composition for the treatment of fibroid of the present invention has the liver reason spleen that relaxes, the function for adjusting blood to warm up palace, resolving hard lump, detoxification of reducing swelling Effect has a good effect treatment fibroid, and overall clinical efficacy rate reaches 82%.Compatibility of the present invention is scientific, it is significant in efficacy, It takes effect rapidly, has no toxic side effect, preparation method is simple, mild condition and stability is good, easy to spread.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below Detailed description.Obviously, described embodiment is only a part of the embodiments of the present invention, instead of all the embodiments. Based on the embodiments of the present invention, those of ordinary skill in the art obtained institute without making creative work There is other embodiment, belongs to the range that the present invention is protected.
Embodiment 1
The present embodiment provides a kind of Chinese medicine composition for treating fibroid, raw material components include:
Radix scrophulariae 12g, Radix Angelicae Sinensis 8g, Rhizoma Chuanxiong 8g, ramulus cinnamomi 12g, Poria cocos 12g, rhizoma cyperi 12g, Radix Notoginseng 5g, spina gleditsiae 24g, honeysuckle 12g, cordate houttuynia 24g, dandelion 24g, Prunella vulgaris 12g, first pearl 5g, leech 8g, Eupolyphoge sinensis 8g, costazia bone 12g, nitre 8g, life are male Oyster 24g, edible tulip 12g, edible tulip bulb 12g, seaweed 12g, thallus laminariae 12g, rhizome of cyrtomium 12g, cockscomb 12g, adlay 24g, semen plantaginis 12g, Radix Glycyrrhizae 8g.
The preparation method of the Chinese medicine composition of the treatment fibroid, comprising the following steps:
(1) raw material cleaned, cleaned, dried, mixed thoroughly later with Alcohol degree for the white wine of 52%Vol, institute The mass ratio for stating raw material and alcohol is 10:1, obtains mixing liquor raw material;
(2) the liquor raw material mild fire frying color of mixing is obtained into raw material after wine toast to intensification;
(3) it is 20nm, raw material after being crushed that raw material nano, which is crushed to partial size, after processing wine;After to the crushing in raw material The rape flower honey of 1/3 mass is added, stirs evenly, the thin ball of every weight 0.1g is made to get the treatment fibroid is arrived Chinese medicine composition.
Embodiment 2
The present embodiment provides a kind of Chinese medicine composition for treating fibroid, raw material components include:
Radix scrophulariae 18g, Radix Angelicae Sinensis 12g, Rhizoma Chuanxiong 12g, ramulus cinnamomi 18g, Poria cocos 18g, rhizoma cyperi 18g, Radix Notoginseng 7g, spina gleditsiae 36g, gold and silver Flower 18g, cordate houttuynia 36g, dandelion 36g, Prunella vulgaris 18g, first pearl 15g, leech 12g, Eupolyphoge sinensis 12g, costazia bone 18g, nitre 12g, raw oyster 36g, edible tulip 18g, edible tulip bulb 18g, seaweed 18g, thallus laminariae 18g, rhizome of cyrtomium 18g, cockscomb 18g, adlay 36g, Semen plantaginis 18g, Radix Glycyrrhizae 12g.
The preparation method of the Chinese medicine composition of the treatment fibroid, comprising the following steps:
(1) raw material cleaned, cleaned, dried, mixed thoroughly later with Alcohol degree for the white wine of 63%Vol, institute The mass ratio for stating raw material and alcohol is 10:2, obtains mixing liquor raw material;
(2) the liquor raw material mild fire frying color of mixing is obtained into raw material after wine toast to intensification;
(3) it is 100nm, raw material after being crushed that raw material nano, which is crushed to partial size, after processing wine;Raw material after to the crushing The middle rape flower honey that 1/5 mass is added, stirs evenly, and the thin ball of every weight 0.3g is made to get the treatment uterus muscle is arrived The Chinese medicine composition of tumor.
Embodiment 3
The present embodiment provides a kind of Chinese medicine composition for treating fibroid, raw material components include:
Radix scrophulariae 15g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 10g, ramulus cinnamomi 15g, Poria cocos 15g, rhizoma cyperi 15g, Radix Notoginseng 6g, spina gleditsiae 30g, gold and silver Flower 15g, cordate houttuynia 30g, dandelion 30g, Prunella vulgaris 15g, first pearl 10g, leech 10g, Eupolyphoge sinensis 10g, costazia bone 15g, nitre 10g, raw oyster 30g, edible tulip 15g, edible tulip bulb 15g, seaweed 15g, thallus laminariae 15g, rhizome of cyrtomium 15g, cockscomb 15g, adlay 30g, Semen plantaginis 15g, Radix Glycyrrhizae 10g.
The preparation method of the Chinese medicine composition of the treatment fibroid, comprising the following steps:
(1) raw material cleaned, cleaned, dried, mixed thoroughly later with Alcohol degree for the white wine of 60%Vol, institute The mass ratio for stating raw material and alcohol is 20:3, obtains mixing liquor raw material;
(2) the liquor raw material mild fire frying color of mixing is obtained into raw material after wine toast to intensification;
(3) it is 60nm, raw material after being crushed that raw material nano, which is crushed to partial size, after processing wine;After to the crushing in raw material The rape flower honey of 1/4 mass is added, stirs evenly, the thin ball of every weight 0.2g is made to get the treatment fibroid is arrived Chinese medicine composition.
Embodiment 4
The present embodiment provides a kind of Chinese medicine composition for treating fibroid, raw material components include:
Radix scrophulariae 12g, Radix Angelicae Sinensis 8g, Rhizoma Chuanxiong 8g, ramulus cinnamomi 12g, Poria cocos 12g, rhizoma cyperi 12g, Radix Notoginseng 5g, spina gleditsiae 24g, honeysuckle 12g, cordate houttuynia 24g, dandelion 24g, Prunella vulgaris 12g, first pearl 5g, leech 8g, Eupolyphoge sinensis 8g, costazia bone 12g, nitre 8g, life are male Oyster 24g, edible tulip 12g, edible tulip bulb 12g, seaweed 12g, thallus laminariae 12g, rhizome of cyrtomium 12g, cockscomb 12g, adlay 24g, semen plantaginis 12g, Radix Glycyrrhizae 8g.
The preparation method of the Chinese medicine composition of the treatment fibroid, comprising the following steps:
(1) each raw material being cleaned, is cleaned, the pure water that 2 times of quality are added impregnates 1h, and high fire decocts 3min, Then turn to be cooked by slow fire 40min, filtrate is obtained by filtration using 300 mesh filter screens;
(2) by the filtrate temperature be 35 DEG C at be condensed into cream, obtain it is described treatment fibroid Chinese medicine composition.
Embodiment 5
The present embodiment provides a kind of Chinese medicine composition for treating fibroid, raw material components include:
Radix scrophulariae 18g, Radix Angelicae Sinensis 12g, Rhizoma Chuanxiong 12g, ramulus cinnamomi 18g, Poria cocos 18g, rhizoma cyperi 18g, Radix Notoginseng 7g, spina gleditsiae 36g, gold and silver Flower 18g, cordate houttuynia 36g, dandelion 36g, Prunella vulgaris 18g, first pearl 15g, leech 12g, Eupolyphoge sinensis 12g, costazia bone 18g, nitre 12g, raw oyster 36g, edible tulip 18g, edible tulip bulb 18g, seaweed 18g, thallus laminariae 18g, rhizome of cyrtomium 18g, cockscomb 18g, adlay 36g, Semen plantaginis 18g, Radix Glycyrrhizae 12g.
The preparation method of the Chinese medicine composition of the treatment fibroid, comprising the following steps:
(1) each raw material being cleaned, is cleaned, the pure water that 4 times of quality are added impregnates 3h, and high fire decocts 7min, Then turn to be cooked by slow fire 140min, filtrate is obtained by filtration using 800 mesh filter screens;
(2) by the filtrate temperature be 45 DEG C at be condensed into cream, obtain it is described treatment fibroid Chinese medicine composition.
Embodiment 6
The present embodiment provides a kind of Chinese medicine composition for treating fibroid, raw material components include:
Radix scrophulariae 15g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 10g, ramulus cinnamomi 15g, Poria cocos 15g, rhizoma cyperi 15g, Radix Notoginseng 6g, spina gleditsiae 30g, gold and silver Flower 15g, cordate houttuynia 30g, dandelion 30g, Prunella vulgaris 15g, first pearl 10g, leech 10g, Eupolyphoge sinensis 10g, costazia bone 15g, nitre 10g, raw oyster 30g, edible tulip 15g, edible tulip bulb 15g, seaweed 15g, thallus laminariae 15g, rhizome of cyrtomium 15g, cockscomb 15g, adlay 30g, Semen plantaginis 15g, Radix Glycyrrhizae 10g.
The preparation method of the Chinese medicine composition of the treatment fibroid, comprising the following steps:
(1) each raw material being cleaned, is cleaned, the pure water that 3 times of quality are added impregnates 2h, and high fire decocts 5min, Then turn to be cooked by slow fire 90min, filtrate is obtained by filtration using 600 mesh filter screens;
(2) by the filtrate temperature be 40 DEG C at be condensed into cream, obtain it is described treatment fibroid Chinese medicine composition.
Experimental example
Effect test is carried out to the Chinese medicine composition for treating fibroid obtained by embodiment 3
1, subjects: patients with uterine myoma 616.
2, it tests process: using Chinese medicine composition produced by the present invention, allow subject using 6 months, then inquire tested Person takes effect, pays a return visit every 2 months primary.
3, test result judgment criteria: (1) effectively: check fibroid diameter reduces before relatively treating;(2) effective: relatively same When participate in experiment other patient uterine's myomata diameters reduce it is more obvious;(3) cure: check fibroid disappears.
4, test result: it is shown in Table 1.
1 test result of table
Therapeutic effect Effectively It is effective It cures
Number 505 431 382
Percentage 82% 70% 62%
From table 1 it follows that fibroid disease of the Chinese medicine composition for the treatment of fibroid of the present invention to patient Shape has good therapeutic effect, and effective percentage is 82%, also sufficiently confirms that Chinese medicine composition of the present invention imitates the treatment of fibroid Fruit.
Typical case
1, Jiao, female, 41 years old.3 months 1 hyper-menorrheas of irregular colporrhagia, dripping urine endlessly, color is dim red, there is clot, companion Lower abdominal distention pain, pain in the loins, dizziness and fatigue.Tongue nature is light, whitish tongue, deep thready pulse are puckery.Ultrasound diagnosis is shown: the visible 2.9cm of anterior uterine wall × , there is compressing in 3.8cm size essence echo group to mucous membrane.Prompt: fibroid.It is treated using this drug paste, each 130ml, 3 times a day, it warmly takes within 60 minutes before the meal.Medication 49 days, B ultrasound check: myomata disappears, uterus normal in size.Check has no multiple after 1 year Hair.
2, week certain, female, 37 years old.Unregular vaginal bleeding in this year, hyper-menorrhea, color it is dim it is red have block, waist and hypogastric pain, It passes through often up to 7-10 days.Gynecologial examination, ultrasound diagnosis are shown: the visible about 6cm × 10cm size essence echo group of anterior uterine wall.Prompt: Fibroid.It is treated using this drug paste, each 130ml warmly takes for 60 minutes before the meal 3 times a day.Medication 56 days, B ultrasound is multiple Look into: myomata disappears, and all symptoms disappear, uterus normal in size.No relapse is checked after 1 year.
3, Shi, female, 46 years old.Suffer from fibroid 3 years, advanced menorrhea more than 10 days, conduct more than 10 days, blood volume was more, menstrual period waist Abdomen very pain, usually leukorrhea amount is more, in the period every time can be stopped with hemostatic, cannot go to work when menses are more.Gynecologial examination: son Such as 7 weeks pregnant sizes in palace, shape is irregular, and matter is hard, does not treat.It is treated using this drug paste, each 130ml, daily 3 It is secondary, it warmly takes within 60 minutes before the meal.After medication 20 days, under menstruation on time, pass through 5 days, blood volume significantly reduces, unused hemostatic menstruation From only.Change and takes pill, each 12g, 3 times a day, 60 minutes warm water delivery services before the meal.Medication 63 days, gynaecology's check: uterus is slightly Greatly, shape rule, 3 years no relapse of follow-up.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.

Claims (10)

1. a kind of Chinese medicine composition for treating fibroid, which is characterized in that raw material components include:
Radix scrophulariae 12-18 parts by weight, Radix Angelicae Sinensis 8-12 parts by weight, Rhizoma Chuanxiong 8-12 parts by weight, ramulus cinnamomi 12-18 parts by weight, Poria cocos 12-18 weight Measure part, rhizoma cyperi 12-18 parts by weight, Radix Notoginseng 5-7 parts by weight, spina gleditsiae 24-36 parts by weight, honeysuckle 12-18 parts by weight, cordate houttuynia 24-36 parts by weight, dandelion 24-36 parts by weight, Prunella vulgaris 12-18 parts by weight, first pearl 5-15 parts by weight, leech 8-12 weight Part, Eupolyphoge sinensis 8-12 parts by weight, costazia bone 12-18 parts by weight, nitre 8-12 parts by weight, raw oyster 24-36 parts by weight, edible tulip 12-18 parts by weight, edible tulip bulb 12-18 parts by weight, seaweed 12-18 parts by weight, thallus laminariae 12-18 parts by weight, rhizome of cyrtomium 12-18 weight Part, cockscomb 12-18 parts by weight, adlay 24-36 parts by weight, semen plantaginis 12-18 parts by weight, Radix Glycyrrhizae 8-12 parts by weight.
2. the Chinese medicine composition for the treatment of fibroid according to claim 1, which is characterized in that raw material components include:
15 parts by weight of radix scrophulariae, 10 parts by weight of Radix Angelicae Sinensis, 10 parts by weight of Rhizoma Chuanxiong, 15 parts by weight of ramulus cinnamomi, 15 parts by weight of Poria cocos, 15 weight of rhizoma cyperi Measure part, 6 parts by weight of Radix Notoginseng, 30 parts by weight of spina gleditsiae, 15 parts by weight of honeysuckle, 30 parts by weight of cordate houttuynia, 30 parts by weight of dandelion, 15 parts by weight of Prunella vulgaris, 10 parts by weight of first pearl, 10 parts by weight of leech, 10 parts by weight of Eupolyphoge sinensis, 15 parts by weight of costazia bone, 10 weight of nitre Measure part, 30 parts by weight of raw oyster, 15 parts by weight of edible tulip, 15 parts by weight of edible tulip bulb, 15 parts by weight of seaweed, 15 parts by weight of thallus laminariae, 15 parts by weight of rhizome of cyrtomium, 15 parts by weight of cockscomb, 30 parts by weight of adlay, 15 parts by weight of semen plantaginis, 10 parts by weight of Radix Glycyrrhizae.
3. the Chinese medicine composition of any one of -2 treatment fibroids according to claim 1, the dosage form of described pharmaceutical composition For pill or paste.
4. a kind of preparation method of the Chinese medicine composition of any one of claim 1-3 treatment fibroid, which is characterized in that The following steps are included:
(1) each raw material cleaned, cleaned, dried, mixed thoroughly later with wine, obtain mixing liquor raw material;
(2) liquor raw material of mixing is subjected to mild fire frying, obtains raw material after wine toast;
(3) raw material nano after wine toast is crushed, raw material after being crushed;Honey is added in raw material after to the crushing, stirs It mixes and thin ball is made uniformly to get the Chinese medicine composition of the treatment fibroid is arrived.
5. treating the preparation method of the Chinese medicine composition of fibroid according to claim 4, which is characterized in that step (1) In, the wine of selection is the white wine that Alcohol degree is 52%Vol-63%Vol;The mass ratio of the raw material and wine is 10:(1-2).
6. treating the preparation method of the Chinese medicine composition of fibroid according to claim 4, which is characterized in that step (3) In, the smashed partial size of raw material is 20-100nm.
7. treating the preparation method of the Chinese medicine composition of fibroid according to claim 4, which is characterized in that step (3) In, honey is rape flower honey;The mass ratio of raw material and rape flower honey is (3-5) after crushing: 1;Every thin ball quality is 0.1g-0.3g。
8. a kind of preparation method of the Chinese medicine composition of any one of claim 1-3 treatment fibroid, which is characterized in that The following steps are included:
(1) each raw material cleaned, cleaned, soaked in water rear high fire and decoct, then turned to be cooked by slow fire, filter is obtained by filtration Liquid;
(2) filtrate is condensed into cream, obtains the Chinese medicine composition of the treatment fibroid.
9. treating the preparation method of the Chinese medicine composition of fibroid according to claim 8, which is characterized in that step (1) In, the mass ratio of raw material and water is 1:(2-4), soaking time 1-3h;High fire decocting time is 3-7min;It is cooked by slow fire the time For 40-140min;Filtering uses 300-800 mesh filter screen.
10. treating the preparation method of the Chinese medicine composition of fibroid according to claim 8, which is characterized in that step (2) In, temperature is 35-45 DEG C when concentration.
CN201811484223.4A 2018-12-05 2018-12-05 A kind of Chinese medicine composition and preparation method thereof for treating fibroid Pending CN109248281A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103585586A (en) * 2013-11-20 2014-02-19 潘恒晔 Traditional Chinese medicine composition for treating uterine fibroids and preparation method of same

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103585586A (en) * 2013-11-20 2014-02-19 潘恒晔 Traditional Chinese medicine composition for treating uterine fibroids and preparation method of same

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Application publication date: 20190122