Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of diabetes, it overcomes the deficiency of existing medicine, can fast, thoroughly treat diabetes.
Technical scheme of the present invention is: a kind of Chinese medicine composition for the treatment of diabetes, it is characterized in that, and by the crude drug of following weight, made: Concha Ostreae 15-25 gram, Radix Polygoni Multiflori 15-25 gram, Cortex Lycii 15-25 gram, Radix Rehmanniae 15-25 gram, Radix Aucklandiae 10-20 gram, Radix Achyranthis Bidentatae 10-20 gram, Poria 10-20 gram, Radix Paeoniae Rubra 10-20 gram, Rhizoma Chuanxiong 10-20 gram, Cortex Moutan 10-20 gram, Os Draconis 10-20 gram, Radix Ophiopogonis 5-15 gram, Fructus Schisandrae Chinensis 5-15 gram, Rhizoma Alismatis 5-15 gram, Fructus Corni 5-15 gram, Radix Codonopsis 5-15 gram, Semen Cuscutae 5-15 gram, Fructus Amomi 3-6 gram, Radix Glycyrrhizae 5-12 gram.
The further technical scheme of the present invention is: a kind of Chinese medicine composition for the treatment of diabetes, it is characterized in that, and by the crude drug of following weight, made: 20 grams of Concha Ostreaes, 20 grams of Radix Polygoni Multiflori, 20 grams of Cortex Lycii, 20 grams of Radix Rehmanniae, 15 grams of the Radix Aucklandiae, 15 grams of Radix Achyranthis Bidentataes, 15 grams, Poria, 15 grams of Radix Paeoniae Rubra, 15 grams of Rhizoma Chuanxiongs, 15 grams of Cortex Moutans, 15 grams of Os Draconis, 10 grams of Radix Ophiopogonis, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Rhizoma Alismatis, 10 grams of Fructus Corni, 10 grams of Radix Codonopsis, 10 grams of Semen Cuscutae, 6 grams of Fructus Amomis, 6 grams, Radix Glycyrrhizae.
Preparation and instructions of taking: raw material is mixed in marmite, adds water and soak in right amount; First intense fire is fried boiling, then with half an hour at a simmer, leaches medicinal liquid, adds water and decocts half an hour more in right amount, then leach medicinal liquid in medicinal residues.Twice medicinal liquid mixes, cools completely, and respectively at half an hour before breakfast, within after supper two hours, takes.
The pharmacological action of each Chinese medicine:
Concha Ostreae: yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduces phlegm, softening the hard mass.Control dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.
Fructus Corni: invigorating the liver and kidney, arresting seminal emission gas, Gu collapse.Control soreness of waist and knee joint, dizzy, tinnitus, sexual impotence, seminal emission, frequent micturition, deficiency of the liver cold and heat.
Radix Polygoni Multiflori: bitter sweet puckery, tepor.Enter liver, kidney channel.Tonifying liver, kidney tonifying, nourishes blood, and dispels the wind.Control hepatic and renal YIN deficiency, sending out must be early white, and blood deficiency is dizzy, and waist knee joint is weak, and muscles and bones is ached, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids.
Cortex Lycii: heat clearing away, removing heat from blood, controls asthenia hectic fever night sweat, lung-heat cough with asthma, carbuncle malignant boil.
Radix Rehmanniae: clearing up internal heat by using drugs of bitter in taste and cold in nature, Gan Hanzhi moistens yin nourishing, for the refrigerant product that moisten, is good at nourishing YIN and clearing away heat removing heat from blood.Effect clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, intestine moistening.
The Radix Aucklandiae: gas fragrance, taste is sweet, bitter, slightly stings tongue.Warm in nature, acrid in the mouth, hardship.Promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For heavy after breast gastral cavity distending pain, dysentery, food stagnation does not disappear, anorexia.
Radix Achyranthis Bidentatae: sweetness and bitterness acid, flat.Enter liver, kidney channel.Raw dissipating blood stasis blood, the subduing inflammation used.Control gonorrhea, hematuria, amenorrhea , mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury.Ripe in invigorating the liver and kidney, bone and muscle strengthening.Control waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.
Poria: sweet light, flat.Enter the heart, spleen, lung meridian.Eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Control dysuria, edema distension, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.
Radix Paeoniae Rubra: bitter in the mouth is flat.Enter liver, spleen channel.Clots absorbing, pain relieving, removing heat from blood, detumescence.Control the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle.
Rhizoma Chuanxiong: acrid in the mouth, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Cortex Moutan: heat clearing away, removing heat from blood, and blood, repercussive.Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion, tells, is defeated in battle, has blood in stool, hectic fever due to YIN-deficiency consumptive fever, and amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.
Os Draconis: tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, insomnia and dreamful sleep, spontaneous sweating, seminal emission stranguria with turbid discharge, tells nosebleed and has blood in stool, bleeding not during menses, dysentery proctoptosis.
Radix Ophiopogonis: sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.
Fructus Schisandrae Chinensis: acid, temperature.Enter lung, kidney channel, astringe the lung, nourishing kidney, promotes the production of body fluid, and receives antiperspirant, arresting seminal emission.Control the deficiency of the lung and breath with cough, xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.
Rhizoma Alismatis: sweet, cold.Enter kidney, urinary bladder channel.Diuretic, eliminating dampness by diuresis, expels the heat-evil.Control dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.
Fructus Corni: invigorating the liver and kidney, arresting seminal emission gas, Gu collapse.Control soreness of waist and knee joint, dizzy, tinnitus, sexual impotence, seminal emission, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart shakes scattered pulse.
Radix Codonopsis: sweet, flat.Start with, meridian of Foot-TAI YIN edema caused by disorder of QI.Invigorating the spleen and replenishing QI, promotes the production of body fluid, and nourishes blood.For the empty asthenia of body of deficiency of QI in middle-JIAO, weakness of the spleen and stomach, deficiency of both QI and blood, controls fatigue and lack of strength, lung qi virtual loss.Control lack of appetite, thirsty, chronic diarrhea, proctoptosis.And the two shallow complexions of losing of QI and blood, dizzy cardiopalmus etc.
Semen Cuscutae: tonifying liver pain, beneficial marrow, improving eyesight.Control soreness of waist and knee joint, quench one's thirst, order is dark.
Fructus Amomi: pungent, temperature.Enter spleen, stomach warp.During circulation of qi promoting is adjusted, stomach function regulating, is amusing.Control stomachache painful abdominal mass swollen, anorexia dyspepsia, dysphagic vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.
Chinese medicine thinks, with the passing of time diabetes, must sap one's vitality, deficiency of both QI and YIN, and it is unable that the deficiency of vital energy is transported blood, the involved and abstruse the kidney usually involved in chronic disease that forms of deficiency of YIN person's blood, the blood stasis syndrome of pathogen usually intruding into collateral in protracted disease.Treatment is attacked parallelly when mending, and gets rid of evils when noticing that dehumidifying, heat clearing away, change are turbid, removing toxic substances, especially will pay attention to the application of blood circulation promoting and blood stasis dispelling principle in this disease treatment.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, clinical observation
1, clinical data: be selected from the outpatient service in year May in June, 2011 to 2013 and inpatient totally 92 examples, the age is 38-69 year, average 54.5 years old.
2, diagnostic criteria:
(1) there is diabetic symptom (polyuria, polydipsia and inexplicable weight loss), and random (any time after the meal) plasma glucose >=11.1mmol/L (200mg/dl);
(2) (fasting at least 8 hours) plasma glucose >=7.0mmol/L (126mg/dl) or on an empty stomach;
Or OGTT2 hour plasma glucose >=11.1mmol/L (200mg/dl) (3)
Fasting glucose damage (IFG): refer to fasting plasma glucose >=6.1mmol/L (110mg/dl), but <7.0mmol/L (126mg/dl).
Impaired glucose tolerance (IGT): refer to OGTT2 hour plasma glucose >=7.8mmol/L (140mg/dl), but <11.1mmol/L (200mg/dl).
3, Therapeutic Method: take medicine of the present invention, decocting boils, takes at twice sooner or later.It within 1 month, is 1 course for the treatment of.
4, efficacy assessment standard:
Effective: after treatment, symptom disappears substantially, fasting glucose < 7.2mmol/L, (130mg/dl), 2 hours blood glucose < 8.3mmol/L(150mg/dl after the meal), twenty-four-hour urine sugar total amount < 10.0g, or blood glucose, twenty-four-hour urine sugar total amount are treated front decline more than 30%.
Effective: after treatment, symptom is obviously improved, fasting glucose < 8.3mmol/L(150mg/dl), 2 hours blood glucose < 10.0mmol/L(180mg/dl after the meal), twenty-four-hour urine sugar total amount < 25.0g, or blood glucose, twenty-four-hour urine sugar total amount are treated front decline more than 10%.
Invalid: after treatment, symptom is not improved, blood glucose, glucose in urine decline and do not reach above-mentioned standard.
5, therapeutic outcome: observe 92 routine diabeticss, effective 84 examples, effective 6 examples, invalid 2 examples.Effective percentage is 91.3%.
6, toxic and side effects analysis
In the 92 routine patients that observe, only have 2 examples to occur laxativeness after taking Chinese medicine of the present invention, the probability that occurs side reaction is only 2.0%, through disposing to the ill side reaction, disappears, and all the other are without any side effects.
In sum, the present invention is used for the treatment of the Chinese medicine composition of diabetes, through clinical trial, shows that it can effectively suppress the development of diabetes, improves patient's symptom, sign, and without obvious toxic-side effects.
Two, model case
Example 1: Liu Lili, female, 47 years old.Suffer from diabetes for many years, once took various antidiabetic drug treatments, poor effect, the state of an illness is serious day by day, existing disease: xerostomia, sweating due to debility, biped are sent out cool, lower limbs edema.Light when heavy during once with Western medicine and treatment by Chinese herbs.Clothes we treated after two courses for the treatment of, and spirit, complexion take a turn for the better, and above-mentioned symptom disappears, and edema disappears.After treatment was fully recovered after one month.
Example 2: Guo Mingliang, man, 61 years old.Patient's diabetes 3 years, polyorexia, thirsty polydipsia, emaciated physique, through diet control and take glyburide and metformin, blood glucose maintains between 10.1-15.2mmol/l, glucose in urine (+++)-(++++), ketoboidies (++), recently aggravation, starts to control with insulin, takes two courses for the treatment of of we, insulin dosage gradually successively decreases, the insulin of stopping using after two courses for the treatment of that continues to take medicine, blood glucose remains between 6.2-7.4mmol/l, glucose in urine (-), continue to strengthen and treat after half a year, be in a good state of health.
Example 3: Sun Mingai, female, 45 years old.Diabetes have been found 5 years.Self-induction is weak, poor appetite, loose stool, polydipsia, polyuria.Take blood sugar lowering western medicine, heavy when light during symptom, glycemic control is undesirable always.In start injection insulinize the year before.1 course for the treatment of of rear use we treatment, weak disappearance, two is just normal, continues to strengthen 3 courses for the treatment of of medication, check kidney series: urine Alb1027mg/L, urine IgG330mg/L, patient's spirit, diet, two are just normal.
The specific embodiment
Embodiment 1: a kind of Chinese medicine composition for the treatment of diabetes, by the crude drug of following weight, made: 20 grams of Concha Ostreaes, 20 grams of Radix Polygoni Multiflori, 20 grams of Cortex Lycii, 20 grams of Radix Rehmanniae, 15 grams of the Radix Aucklandiae, 15 grams of Radix Achyranthis Bidentataes, 15 grams, Poria, 15 grams of Radix Paeoniae Rubra, 15 grams of Rhizoma Chuanxiongs, 15 grams of Cortex Moutans, 15 grams of Os Draconis, 10 grams of Radix Ophiopogonis, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Rhizoma Alismatis, 10 grams of Fructus Corni, 10 grams of Radix Codonopsis, 10 grams of Semen Cuscutae, 6 grams of Fructus Amomis, 6 grams, Radix Glycyrrhizae.
Preparation and instructions of taking: raw material is mixed in marmite, adds water and soak in right amount; First intense fire is fried boiling, then with half an hour at a simmer, leaches medicinal liquid, adds water and decocts half an hour more in right amount, then leach medicinal liquid in medicinal residues.Twice medicinal liquid mixes, cools completely, and respectively at half an hour before breakfast, within after supper two hours, takes.
Embodiment 2: a kind of Chinese medicine composition for the treatment of diabetes, by the crude drug of following weight, made: 20 grams of Concha Ostreaes, 20 grams of Radix Polygoni Multiflori, 20 grams of Cortex Lycii, 20 grams of Radix Rehmanniae, 20 grams of the Radix Aucklandiae, 20 grams of Radix Achyranthis Bidentataes, 15 grams, Poria, 15 grams of Radix Paeoniae Rubra, 15 grams of Rhizoma Chuanxiongs, 15 grams of Cortex Moutans, 15 grams of Os Draconis, 15 grams of Radix Ophiopogonis, 15 grams of Fructus Schisandrae Chinensis, 15 grams of Rhizoma Alismatis, 15 grams of Fructus Corni, 15 grams of Radix Codonopsis, 10 grams of Semen Cuscutae, 6 grams of Fructus Amomis, 6 grams, Radix Glycyrrhizae.
Preparation and instructions of taking: with example one.
Embodiment 3: a kind of Chinese medicine composition for the treatment of diabetes, by the crude drug of following weight, made: 20 grams of Concha Ostreaes, 20 grams of Radix Polygoni Multiflori, 20 grams of Cortex Lycii, 20 grams of Radix Rehmanniae, 15 grams of the Radix Aucklandiae, 15 grams of Radix Achyranthis Bidentataes, 15 grams, Poria, 15 grams of Radix Paeoniae Rubra, 15 grams of Rhizoma Chuanxiongs, 15 grams of Cortex Moutans, 15 grams of Os Draconis, 10 grams of Radix Ophiopogonis, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Rhizoma Alismatis, 10 grams of Fructus Corni, 10 grams of Radix Codonopsis, 10 grams of Semen Cuscutae, 6 grams of Fructus Amomis, 6 grams, Radix Glycyrrhizae.
Preparation and instructions of taking: with example one.
Embodiment 4: a kind of Chinese medicine composition for the treatment of diabetes, by the crude drug of following weight, made: 25 grams of Concha Ostreaes, 25 grams of Radix Polygoni Multiflori, 20 grams of Cortex Lycii, 20 grams of Radix Rehmanniae, 20 grams of the Radix Aucklandiae, 20 grams of Radix Achyranthis Bidentataes, 15 grams, Poria, 15 grams of Radix Paeoniae Rubra, 15 grams of Rhizoma Chuanxiongs, 15 grams of Cortex Moutans, 15 grams of Os Draconis, 10 grams of Radix Ophiopogonis, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Rhizoma Alismatis, 10 grams of Fructus Corni, 10 grams of Radix Codonopsis, 10 grams of Semen Cuscutae, 3 grams of Fructus Amomis, 6 grams, Radix Glycyrrhizae.
Preparation and instructions of taking: with example one.
Embodiment 5: a kind of Chinese medicine composition for the treatment of diabetes, by the crude drug of following weight, made: 20 grams of Concha Ostreaes, 20 grams of Radix Polygoni Multiflori, 20 grams of Cortex Lycii, 15 grams of Radix Rehmanniae, 15 grams of the Radix Aucklandiae, 15 grams of Radix Achyranthis Bidentataes, 15 grams, Poria, 15 grams of Radix Paeoniae Rubra, 15 grams of Rhizoma Chuanxiongs, 12 grams of Cortex Moutans, 12 grams of Os Draconis, 12 grams of Radix Ophiopogonis, 12 grams of Fructus Schisandrae Chinensis, 10 grams of Rhizoma Alismatis, 10 grams of Fructus Corni, 10 grams of Radix Codonopsis, 10 grams of Semen Cuscutae, 6 grams of Fructus Amomis, 6 grams, Radix Glycyrrhizae.
Preparation and instructions of taking: with example one.