CN105327102A - Traditional Chinese medicine tablets for treating hyperplasia of mammary glands and preparing method of traditional Chinese medicine tablets - Google Patents
Traditional Chinese medicine tablets for treating hyperplasia of mammary glands and preparing method of traditional Chinese medicine tablets Download PDFInfo
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Abstract
The invention discloses traditional Chinese medicine tablets for treating hyperplasia of mammary glands and a preparing method of the traditional Chinese medicine tablets. The traditional Chinese medicine tablets are prepared from, by weight, 15-25 parts of Philippine violet herb, 10-20 parts of dandelions, 8-16 parts of loofah sponge, 8-16 parts of cortex albiziae, 5-15 parts of rape seeds, 5-15 parts of pericarpium citri reticulatae viride, 5-15 parts of fritillaria cirrhosa, 3-13 parts of tangerine seeds, 3-13 parts of peach kernels, 2-8 parts of sappanwood, 2-8 parts of citron and 1-5 parts of China roses. Common traditional Chinese medicinal materials are adopted as raw materials, and the traditional Chinese medicine tablets for treating hyperplasia of mammary glands are scientific in formulation, low in cost, comprehensive in treatment, remarkable in curative effect and free of side effects, have the effects of soothing the liver and regulating the circulation of qi, promoting blood circulation to remove blood stasis, reducing phlegm and softening hard mass, and relieving swelling and pain, and can effectively treat hyperplasia of mammary glands, and hyperplasia of mammary glands is not prone to relapse.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicinal tablet for the treatment of cyclomastopathy and preparation method thereof.
Background technology
Cyclomastopathy, have another name called cyclomastopathy, mammary dysplasia, Fibrocystic disease etc., refer to the individual event of breast duct, lobules of mammary gland, acinar epithelia, fibrous tissue or multinomial hyperplasia of prostate, the feature of primary disease is the hypertrophy of mammary gland constituent, structure, quantity and tissue morphology show exception, be the modal cystic hyperplasia of breast of women, sickness rate accounts for the first place of mastopathy.This sick sickness rate is in the trend that rises year by year in recent years, and the age also more and more becomes younger, be mainly in 30-50 year women, onset peak be 35-40 year.
Primary disease reason is not yet clear and definite so far, mainly thinks at present and the endocrine dysfunction of human body, particularly relevant with the ovarian dysfunction of women.Common sympton has: distending pain of the breast or twinge, lump in breast, nipple discharge, and discharge mostly is faint yellow or light oyster white, menoxenia, feelings will change etc.At present, modern Western medicine lacks the method for effectively treatment cyclomastopathy, mainly based on Drug therapy, adopts Hormone Replacement Therapy more, but easily recurs, and curative effect is not remarkable, and side effect is large, and likely upsets the fine balance between human hormone.Cyclomastopathy shows with its Clinical symptoms, suitable with the disease such as the traditional Chinese medical science " nodules of the breast ", " newborn pestilence ", " nodule in the breast ".The traditional Chinese medical science is thought, this sick pathogenic factor many with internal organs dysfunction, qi-blood disharmony relevant, the liver spleen of pathological changes internal organs duty, especially the spleen soil people of weakness or the pungent delicious food savoury of surfeit, damage spleen soil, and it is not normal to cause the native transportation capabilities of spleen, gathering wets as expectorant or innately introverted, emotion is constrained, and good sulky or irascible temperament, dynamic then irritability or because of damaged by excess of seven emotions, be worried excessively, and cause the liver failing to maintain the normal flow of QI, Yu Ercheng expectorant etc., all can cause phlegm-damp to be tied poly-, coagulation of QI-blood and form lump.Therefore, the traditional Chinese medical science is mainly with blood circulation promoting and blood stasis dispelling in treatment primary disease, and dispersing the stagnated live-QI to relieve the stagnation of QI is main.
In existing patent document, Authorization Notice No. CN103505696B(application number 201210219064.1) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of cyclomastopathy and preparation method thereof, its raw material prescription feature is Spina Gleditsiae 100g, Rhizoma Curcumae 50g, Radix Aucklandiae 50g, Rhizoma Cyperi 40g, Radix Angelicae Dahuricae 40g, Semen Vaccariae 40g, Alumen 40g, Rhizoma Corydalis 40g, Herba Asari 30g, Borneolum Syntheticum 10g, Oleum Anisi Stellati 5g, Oleum Cinnamomi 5g, vaseline 400g, stearic acid 150g, glycerol 50g.
Although the medicine of more existing treatment cyclomastopathy, but also exists the shortcomings such as preparation trouble, drug effect are remarkable, treatment time is long in the traditional Chinese medical science.
Summary of the invention
An object of the present invention overcomes the deficiencies in the prior art, provides one to prepare simply, and treatment is comprehensively, evident in efficacy, not easily recurs, the Chinese medicinal tablet of the treatment cyclomastopathy had no side effect.
In order to solve the problems of the technologies described above, the technical solution adopted in the present invention is:
Treat a Chinese medicinal tablet for cyclomastopathy, take off the raw material of Chinese medicine stating weight proportion and be prepared from: Herba Violae 15-25 part, Herba Taraxaci 10-20 part, Retinervus Luffae Fructus 8-16 part, Cortex Albiziae 8-16 part, Semen Brassicae Campestris 5-15 part, Pericarpium Citri Reticulatae Viride 5-15 part, Bulbus Fritillariae Cirrhosae 5-15 part, Semen Citri Reticulatae 3-13 part, Semen Persicae 3-13 part, Lignum Sappan 2-8 part, Fructus Citri 2-8 part, Flos Rosae Chinensis 1-5 part.
A kind of Chinese medicinal tablet for the treatment of cyclomastopathy, preferred scheme, takes off the raw material of Chinese medicine stating weight proportion and is prepared from: Herba Violae 18-22 part, Herba Taraxaci 13-17 part, Retinervus Luffae Fructus 10-14 part, Cortex Albiziae 10-14 part, Semen Brassicae Campestris 8-12 part, Pericarpium Citri Reticulatae Viride 8-12 part, Bulbus Fritillariae Cirrhosae 8-12 part, Semen Citri Reticulatae 6-10 part, Semen Persicae 6-10 part, Lignum Sappan 4-6 part, Fructus Citri 4-6 part, Flos Rosae Chinensis 2-4 part.
A kind of Chinese medicinal tablet for the treatment of cyclomastopathy, preferred scheme, takes off the raw material of Chinese medicine stating weight proportion and is prepared from: Herba Violae 20 parts, Herba Taraxaci 15 parts, Retinervus Luffae Fructus 12 parts, Cortex Albiziae 12 parts, Semen Brassicae Campestris 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Bulbus Fritillariae Cirrhosae 10 parts, Semen Citri Reticulatae 8 parts, 8 parts, Semen Persicae, Lignum Sappan 5 parts, Fructus Citri 5 parts, Flos Rosae Chinensis 3 parts.
Another object of the present invention is to provide the preparation method of the Chinese medicinal tablet of above-mentioned treatment cyclomastopathy.
Treat a preparation method for the Chinese medicinal tablet of cyclomastopathy, step is as follows:
Step one: Retinervus Luffae Fructus is removed impurity and residual seed, beat flat, stripping and slicing, by residual for Semen Persicae removing nucleocapsid and impurity;
Step 2: just Pericarpium Citri Reticulatae Viride remove impurity, cleans, section, after drying, adds its raw material weight 0.1-0.3 rice vinegar doubly and mixes thoroughly, moistening 8-12min;
Step 3: by Semen Citri Reticulatae remove impurity, after cleaning, drying, adding its raw material weight 0.3-0.7 times of mass concentration is that the saline of 5%-10% is mixed thoroughly, moistening 8-12min;
Step 4: by the Retinervus Luffae Fructus of step one, Semen Persicae, the Pericarpium Citri Reticulatae Viride of step 2, the Semen Citri Reticulatae of step 3 is placed in 50 DEG C of pots respectively, and slow fire is fried to yellow, takes out, is crushed to 120 object fine powders after cooling, for subsequent use;
Step 5: by Herba Violae, Herba Taraxaci, Cortex Albiziae, Semen Brassicae Campestris, Bulbus Fritillariae Cirrhosae, Lignum Sappan, Fructus Citri, Flos Rosae Chinensis remove impurity, clean, cutting into slices is placed in marmite, add the water soaking 30-50 minute of raw material weight 3-7 times 15-25 DEG C, then decoct with high heat to boiling, use slow fire instead to continue to decoct 15-35min, filter, leach medicinal residues, obtain filtrate;
Step 6: the extractum filtrate of step 4 being evaporated under 65 DEG C of conditions relative density 1.20, then adds the fine powder that step 5 obtains, mix homogeneously, dries the Chinese medicinal tablet that namely rear tabletted obtains treatment cyclomastopathy for 70 DEG C.
The preparation method of the Chinese medicinal tablet of above-mentioned treatment cyclomastopathy, step 2 adds Pericarpium Citri Reticulatae Viride raw material weight 0.15-0.25 rice vinegar doubly and mixes thoroughly, moistening 9-11min; Preferably, the rice vinegar adding Pericarpium Citri Reticulatae Viride raw material weight 0.2 times is mixed thoroughly, moistening 10min.
The preparation method of the Chinese medicinal tablet of above-mentioned treatment cyclomastopathy, it is that the saline of 7%-9% is mixed thoroughly that step 3 adds Semen Citri Reticulatae raw material weight 0.4-0.6 times of mass concentration, moistening 9-11min; Preferably, add Semen Citri Reticulatae raw material weight 0.5 times of mass concentration be 8% saline mix thoroughly, moistening 10min.
The preparation method of the Chinese medicinal tablet of above-mentioned treatment cyclomastopathy, the water soaking 35-45 minute that step slender acanthopanax raw material weight is 4-6 times 18-22 DEG C, then decocts to boiling with high heat, uses slow fire instead and continues to decoct 20-30min; Preferably, add the water soaking 40 minutes of raw material weight 5 times 20 DEG C, then decoct to boiling with high heat, use slow fire instead and continue to decoct 25min.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Violae: cold in nature, bitter in the mouth, pungent.GUIXIN warp, Liver Channel.Effect and effect: heat-clearing and toxic substances removing, cool detumescence.Belong to the heat and toxic materials clearing away medicine of antipyretic subordinate classification.With controlling the caused disease such as furuncle carbuncle, acute mastitis, acute appendicitis, erysipelas of pyretic toxicity carbuncle knot; And liver-heat conjunctival congestion and swelling pain, venom etc.
Herba Taraxaci: cold in nature, bitter in the mouth, sweet.Return Liver Channel, stomach warp.Effect and effect: heat-clearing and toxic substances removing, diuresis eliminating stagnation.Treatment acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
Retinervus Luffae Fructus: property is put down, sweet in the mouth.Return lung meridian, stomach warp, Liver Channel.Effect and effect: invigorate blood circulation, dredging collateral, to dispel the wind.With controlling stagnation of QI-blood that a variety of causes causes, venation obstructed pain in chest and hypochondrium, stomachache, lumbago, testicular pain, married woman's dysmenorrhoea, galactostasis etc.; Cough due to lung-heat, hemorrhoid complicated by anal fistula, metrorrhagia etc.
Cortex Albiziae: property is put down, sweet in the mouth.GUIXIN warp, Liver Channel, lung meridian.Effect and effect: resolving stagnation for tranquilization, promoting blood circulation and detumescence.With controlling, irritability, melancholy insomnia, lung abscess skin ulcer are swollen, traumatic injury.Modern with controlling irritability, melancholy insomnia.
Semen Brassicae Campestris: property is put down, acrid in the mouth, sweet.Return Liver Channel, large intestine channel.Effect and effect: blood circulation promoting and blood stasis dispelling, dispersing swelling and dissipating binds, loosening bowel to relieve constipation.Cure mainly prolonged lochia, abdominal pain due to blood stasis, dysmenorrhea, discharging fresh blood stool, dysentery, Fengshi Guanjie swells and ache, carbuncle erysipelas, acute mastitis, constipation, adhesive ileus.
Pericarpium Citri Reticulatae Viride: warm in nature, bitter in the mouth, pungent.Return Liver Channel, gallbladder meridian, stomach warp.Effect and effect: soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.Belong to QI regulating medicine.With controlling distending pain in the chest and hypochondrium, hernia pain, nodules of the breast, acute mastitis, stagnation of QI due to dyspepsia, abdominal distention.
Bulbus Fritillariae Cirrhosae: cold nature, bitter in the mouth, sweet.Return lung meridian, heart channel.Effect and effect: clearing heat and moistening lung, preventing phlegm from forming and stopping coughing.With controlling cough due to consumptive disease, spitting of blood of spitting, ambition pent-up, lung abscess, goiter, scrofula, sore throat, acute mastitis.
Semen Citri Reticulatae: property is put down, bitter in the mouth.Return Liver Channel, kidney channel.Effect and effect: regulate the flow of vital energy, eliminating stagnation, pain relieving.With controlling hernia pain, painful and swollen testis, acute mastitis nodules of the breast.
Semen Persicae: property is put down, bitter in the mouth, sweet.GUIXIN warp, Liver Channel, large intestine channel.Effect and effect: activating blood circulation and dissipating phlegm, loosening bowel to relieve constipation.With controlling amenorrhea, dysmenorrhea, mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Lignum Sappan: property is put down, sweet in the mouth, salty.GUIXIN warp, Liver Channel, spleen channel.Effect and effect: promoting the circulation of blood blood stasis dispelling, reducing swelling and alleviating pain.With controlling traumatic injury, the fracture injury of tendon and muscle, the stasis of blood is stagnant to swell and ache, amenorrhea dysmenorrhea, postpartum stagnation, breast ventral spine pain, ulcer sore pain.
Fructus Citri: warm in nature, acrid in the mouth, hardship, acid.Return Liver Channel, spleen channel, lung meridian.Effect and effect: liver-smoothing, qi-regulating, alleviating distention in middle-JIAO, to reduce phlegm.With controlling stagnation of liver-QI and stomach-QI, sternal rib pain, gastral cavity abdomen feeling of fullness, vomiting eructation, abundant expectoration cough.
Flos Rosae Chinensis: warm in nature, sweet in the mouth.Return Liver Channel.Effect and effect: promoting blood flow to regulate menstruation, dispersing the stagnated live-QI to relieve the stagnation of QI.The menoxenia caused with controlling depression of liver-QI, dysmenorrhea, amenorrhea, chest and abdomen swelling and pain, traumatic injury, blood stasis are swollen and ache, swollen ulcer drug and scrofula etc.
Compared with prior art, beneficial effect of the present invention is:
The present invention treats the Chinese medicinal tablet of cyclomastopathy, adopts common Chinese medicine material as raw material, scientific formulation, with low cost, treatment is comprehensively, evident in efficacy, not easily recur, have no side effect, there is effect of liver-smoothing, qi-regulating, blood circulation promoting and blood stasis dispelling, resolving phlegm and softening hard masses, reducing swelling and alleviating pain, effectively can treat cyclomastopathy.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1treat a Chinese medicinal tablet for cyclomastopathy, take off the raw material of Chinese medicine stating weight proportion and be prepared from (getting 1g for every part): Herba Violae 15 parts, Herba Taraxaci 10 parts, Retinervus Luffae Fructus 8 parts, Cortex Albiziae 8 parts, Semen Brassicae Campestris 5 parts, 5 parts, Pericarpium Citri Reticulatae Viride, Bulbus Fritillariae Cirrhosae 5 parts, Semen Citri Reticulatae 3 parts, 3 parts, Semen Persicae, Lignum Sappan 2 parts, Fructus Citri 2 parts, Flos Rosae Chinensis 1 part.
The preparation method of the Chinese medicinal tablet of above-mentioned treatment cyclomastopathy, step is as follows:
Step one: Retinervus Luffae Fructus is removed impurity and residual seed, beat flat, stripping and slicing, by residual for Semen Persicae removing nucleocapsid and impurity;
Step 2: just Pericarpium Citri Reticulatae Viride remove impurity, cleans, section, and after drying, the rice vinegar adding its raw material weight 0.1 times is mixed thoroughly, moistening 8min;
Step 3: by Semen Citri Reticulatae remove impurity, after cleaning, drying, add its raw material weight 0.3 times of mass concentration be 5% saline mix thoroughly, moistening 8min;
Step 4: by the Retinervus Luffae Fructus of step one, Semen Persicae, the Pericarpium Citri Reticulatae Viride of step 2, the Semen Citri Reticulatae of step 3 is placed in 50 DEG C of pots respectively, and slow fire is fried to yellow, takes out, is crushed to 120 object fine powders after cooling, for subsequent use;
Step 5: by Herba Violae, Herba Taraxaci, Cortex Albiziae, Semen Brassicae Campestris, Bulbus Fritillariae Cirrhosae, Lignum Sappan, Fructus Citri, Flos Rosae Chinensis remove impurity, clean, cutting into slices is placed in marmite, add the water soaking 30 minutes of raw material weight 3 times 15 DEG C, then decoct with high heat to boiling, use slow fire instead to continue to decoct 15min, filter, leach medicinal residues, obtain filtrate;
Step 6: the extractum filtrate of step 4 being evaporated under 65 DEG C of conditions relative density 1.20, then adds the fine powder that step 5 obtains, mix homogeneously, dries the Chinese medicinal tablet that namely rear tabletted obtains treatment cyclomastopathy for 70 DEG C.
model case one:grandson xx, female is 37 years old, married.Patient started distending pain of the breast in menstrual period before 2 years, can touch two scleromas in right breast, and later scleroma is cumulative, menstrual period mastalgia very, menstruation irregularis.The right newborn outward appearance of patient is without exception on inspection, and outer downside can touch 2 × 2cm, 2 × 3cm size lump respectively, and quality is comparatively hard, and surface is still smooth, clear border, with surrounding tissue without adhesion.Be diagnosed as cyclomastopathy, doctor gives the Chinese medicinal tablet treatment of the treatment cyclomastopathy of its embodiment of the present invention 1, and after treating 1 week, menstrual period, lump in breast diminished, pain relief, continual cure is after 1 week, and lump disappears completely, and breast is pain no longer, recovery from illness, paid a return visit after 1 year, without recurrence.
embodiment 2treat a Chinese medicinal tablet for cyclomastopathy, take off the raw material of Chinese medicine stating weight proportion and be prepared from (getting 1g for every part): Herba Violae 25 parts, Herba Taraxaci 20 parts, Retinervus Luffae Fructus 16 parts, Cortex Albiziae 16 parts, Semen Brassicae Campestris 15 parts, 15 parts, Pericarpium Citri Reticulatae Viride, Bulbus Fritillariae Cirrhosae 15 parts, Semen Citri Reticulatae 13 parts, 13 parts, Semen Persicae, Lignum Sappan 8 parts, Fructus Citri 8 parts, Flos Rosae Chinensis 5 parts.
The preparation method of the Chinese medicinal tablet of above-mentioned treatment cyclomastopathy, step is as follows:
Step one: Retinervus Luffae Fructus is removed impurity and residual seed, beat flat, stripping and slicing, by residual for Semen Persicae removing nucleocapsid and impurity;
Step 2: just Pericarpium Citri Reticulatae Viride remove impurity, cleans, section, and after drying, the rice vinegar adding its raw material weight 0.3 times is mixed thoroughly, moistening 12min;
Step 3: by Semen Citri Reticulatae remove impurity, after cleaning, drying, add its raw material weight 0.7 times of mass concentration be 10% saline mix thoroughly, moistening 12min;
Step 4: by the Retinervus Luffae Fructus of step one, Semen Persicae, the Pericarpium Citri Reticulatae Viride of step 2, the Semen Citri Reticulatae of step 3 is placed in 50 DEG C of pots respectively, and slow fire is fried to yellow, takes out, is crushed to 120 object fine powders after cooling, for subsequent use;
Step 5: by Herba Violae, Herba Taraxaci, Cortex Albiziae, Semen Brassicae Campestris, Bulbus Fritillariae Cirrhosae, Lignum Sappan, Fructus Citri, Flos Rosae Chinensis remove impurity, clean, cutting into slices is placed in marmite, add the water soaking 50 minutes of raw material weight 7 times 25 DEG C, then decoct with high heat to boiling, use slow fire instead to continue to decoct 35min, filter, leach medicinal residues, obtain filtrate;
Step 6: the extractum filtrate of step 4 being evaporated under 65 DEG C of conditions relative density 1.20, then adds the fine powder that step 5 obtains, mix homogeneously, dries the Chinese medicinal tablet that namely rear tabletted obtains treatment cyclomastopathy for 70 DEG C.
embodiment 3treat a Chinese medicinal tablet for cyclomastopathy, take off the raw material of Chinese medicine stating weight proportion and be prepared from (getting 1g for every part): Herba Violae 18 parts, Herba Taraxaci 13 parts, Retinervus Luffae Fructus 10 parts, Cortex Albiziae 10 parts, Semen Brassicae Campestris 8 parts, 8 parts, Pericarpium Citri Reticulatae Viride, Bulbus Fritillariae Cirrhosae 8 parts, Semen Citri Reticulatae 6 parts, 6 parts, Semen Persicae, Lignum Sappan 4 parts, Fructus Citri 4 parts, Flos Rosae Chinensis 2 parts.
The preparation method of the Chinese medicinal tablet of above-mentioned treatment cyclomastopathy, step is as follows:
Step one: Retinervus Luffae Fructus is removed impurity and residual seed, beat flat, stripping and slicing, by residual for Semen Persicae removing nucleocapsid and impurity;
Step 2: just Pericarpium Citri Reticulatae Viride remove impurity, cleans, section, and after drying, the rice vinegar adding its raw material weight 0.15 times is mixed thoroughly, moistening 9min;
Step 3: by Semen Citri Reticulatae remove impurity, after cleaning, drying, add its raw material weight 0.4 times of mass concentration be 7% saline mix thoroughly, moistening 9min;
Step 4: by the Retinervus Luffae Fructus of step one, Semen Persicae, the Pericarpium Citri Reticulatae Viride of step 2, the Semen Citri Reticulatae of step 3 is placed in 50 DEG C of pots respectively, and slow fire is fried to yellow, takes out, is crushed to 120 object fine powders after cooling, for subsequent use;
Step 5: by Herba Violae, Herba Taraxaci, Cortex Albiziae, Semen Brassicae Campestris, Bulbus Fritillariae Cirrhosae, Lignum Sappan, Fructus Citri, Flos Rosae Chinensis remove impurity, clean, cutting into slices is placed in marmite, add the water soaking 35 minutes of raw material weight 4 times 18 DEG C, then decoct with high heat to boiling, use slow fire instead to continue to decoct 20min, filter, leach medicinal residues, obtain filtrate;
Step 6: the extractum filtrate of step 4 being evaporated under 65 DEG C of conditions relative density 1.20, then adds the fine powder that step 5 obtains, mix homogeneously, dries the Chinese medicinal tablet that namely rear tabletted obtains treatment cyclomastopathy for 70 DEG C.
model case two:wu xx, female is 28 years old, married.Patient likes sulky at ordinary times, cause anger after feel distending pain of the breast, angry recurrence whenever later, after to make a return journey examination in hospital, the outer upper limit of left breast and right breast outward lower limit can touch differ in size and harder irregular tuberosity, demarcate unclear with surrounding tissue, B ultrasonic shows: bilateral breast owes clear, structure disturbance, body of gland catheter diameter is without obvious expansion, be diagnosed as cyclomastopathy, give the Chinese medicinal tablet treatment of the treatment cyclomastopathy of its embodiment of the present invention 3, treat after 5 days, self-induction lump in breast diminishes, pain relief, continual cure is after 10 days, cure completely, so far without recurrence.
embodiment 4treat a Chinese medicinal tablet for cyclomastopathy, take off the raw material of Chinese medicine stating weight proportion and be prepared from (getting 1g for every part): Herba Violae 22 parts, Herba Taraxaci 17 parts, Retinervus Luffae Fructus 14 parts, Cortex Albiziae 14 parts, Semen Brassicae Campestris 12 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Bulbus Fritillariae Cirrhosae 12 parts, Semen Citri Reticulatae 10 parts, 10 parts, Semen Persicae, Lignum Sappan 6 parts, Fructus Citri 6 parts, Flos Rosae Chinensis 4 parts.
The preparation method of the Chinese medicinal tablet of above-mentioned treatment cyclomastopathy, step is as follows:
Step one: Retinervus Luffae Fructus is removed impurity and residual seed, beat flat, stripping and slicing, by residual for Semen Persicae removing nucleocapsid and impurity;
Step 2: just Pericarpium Citri Reticulatae Viride remove impurity, cleans, section, and after drying, the rice vinegar adding its raw material weight 0.25 times is mixed thoroughly, moistening 11min;
Step 3: by Semen Citri Reticulatae remove impurity, after cleaning, drying, add its raw material weight 0.6 times of mass concentration be 9% saline mix thoroughly, moistening 11min;
Step 4: by the Retinervus Luffae Fructus of step one, Semen Persicae, the Pericarpium Citri Reticulatae Viride of step 2, the Semen Citri Reticulatae of step 3 is placed in 50 DEG C of pots respectively, and slow fire is fried to yellow, takes out, is crushed to 120 object fine powders after cooling, for subsequent use;
Step 5: by Herba Violae, Herba Taraxaci, Cortex Albiziae, Semen Brassicae Campestris, Bulbus Fritillariae Cirrhosae, Lignum Sappan, Fructus Citri, Flos Rosae Chinensis remove impurity, clean, cutting into slices is placed in marmite, add the water soaking 45 minutes of raw material weight 6 times 22 DEG C, then decoct with high heat to boiling, use slow fire instead to continue to decoct 30min, filter, leach medicinal residues, obtain filtrate;
Step 6: the extractum filtrate of step 4 being evaporated under 65 DEG C of conditions relative density 1.20, then adds the fine powder that step 5 obtains, mix homogeneously, dries the Chinese medicinal tablet that namely rear tabletted obtains treatment cyclomastopathy for 70 DEG C.
embodiment 5treat a Chinese medicinal tablet for cyclomastopathy, take off the raw material of Chinese medicine stating weight proportion and be prepared from (getting 1g for every part): Herba Violae 20 parts, Herba Taraxaci 15 parts, Retinervus Luffae Fructus 12 parts, Cortex Albiziae 12 parts, Semen Brassicae Campestris 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Bulbus Fritillariae Cirrhosae 10 parts, Semen Citri Reticulatae 8 parts, 8 parts, Semen Persicae, Lignum Sappan 5 parts, Fructus Citri 5 parts, Flos Rosae Chinensis 3 parts.
The preparation method of the Chinese medicinal tablet of above-mentioned treatment cyclomastopathy, step is as follows:
Step one: Retinervus Luffae Fructus is removed impurity and residual seed, beat flat, stripping and slicing, by residual for Semen Persicae removing nucleocapsid and impurity;
Step 2: just Pericarpium Citri Reticulatae Viride remove impurity, cleans, section, and after drying, the rice vinegar adding its raw material weight 0.2 times is mixed thoroughly, moistening 10min;
Step 3: by Semen Citri Reticulatae remove impurity, after cleaning, drying, add its raw material weight 0.5 times of mass concentration be 8% saline mix thoroughly, moistening 10min;
Step 4: by the Retinervus Luffae Fructus of step one, Semen Persicae, the Pericarpium Citri Reticulatae Viride of step 2, the Semen Citri Reticulatae of step 3 is placed in 50 DEG C of pots respectively, and slow fire is fried to yellow, takes out, is crushed to 120 object fine powders after cooling, for subsequent use;
Step 5: by Herba Violae, Herba Taraxaci, Cortex Albiziae, Semen Brassicae Campestris, Bulbus Fritillariae Cirrhosae, Lignum Sappan, Fructus Citri, Flos Rosae Chinensis remove impurity, clean, cutting into slices is placed in marmite, add the water soaking 40 minutes of raw material weight 5 times 20 DEG C, then decoct with high heat to boiling, use slow fire instead to continue to decoct 25min, filter, leach medicinal residues, obtain filtrate;
Step 6: the extractum filtrate of step 4 being evaporated under 65 DEG C of conditions relative density 1.20, then adds the fine powder that step 5 obtains, mix homogeneously, dries the Chinese medicinal tablet that namely rear tabletted obtains treatment cyclomastopathy for 70 DEG C.
experimental example:1, selection of clinical: in order to verify that the present invention treats the effect of the Chinese medicinal tablet of cyclomastopathy, we have extracted 400 patients and have carried out the experiment of medicine, be equally divided into two groups, experimental group and matched group, two groups in age, clinical manifestation etc. through statistical analysis there was no significant difference.
2, diagnostic criteria: clinical manifestation: distending pain of the breast and lump, some patients has periodically, and premenstrual pain increases the weight of, and alleviates or disappear after menstrual onset, and the whole menstrual cycle of some patients has pain; Health check-up finds that side or bilateral breast have diffuse thickening, can be confined to a mammary gland part, also dispersible in whole mammary gland, lump is graininess, nodositas or lamellar, not of uniform size, and matter is tough not hard, normal is multiple, and be found in side, lump and surrounding tissue are demarcated unclear; Ultrasonic examination: mammary gland body structure is disorderly, Echo heterogenicity.
3, Therapeutic Method:
Experimental group: the Chinese medicinal tablet adopting the present invention's treatment cyclomastopathy, every day 2 times, each 1.
Matched group: take methyl testosterone before menstrual onset, 3 times on the 1st, each 5mg.
4, curative effect situation criterion: cure: treat after 1 month, mastalgia disappears, and lump disappears, and nipple is without discharge, and menstrual cycle is normal; Effective: treat after 1 month, lump maximum gauge reduces, and mastalgia and nipple discharge alleviate, and menstrual cycle is normal; Invalid: to treat after 1 month, clinical symptoms is without improvement or increase the weight of.
Accurately the data of two groups of experiments are added up and mathematical analysis, obtain specific experiment result as following table:
Prove through clinical trial, the cure rate of Chinese medicinal tablet treatment cyclomastopathy of the present invention is 82%, effective percentage is 98%, compared with the effect for the treatment of cyclomastopathy with oral methyl testosterone, have drug effect significantly, treating both the principal and secondary aspects of a disease, not easily recur, have no side effect, the advantage of drug safety, effectively can treat cyclomastopathy.
Claims (9)
1. treat a Chinese medicinal tablet for cyclomastopathy, it is characterized in that: take off the raw material of Chinese medicine stating weight proportion and be prepared from: Herba Violae 15-25 part, Herba Taraxaci 10-20 part, Retinervus Luffae Fructus 8-16 part, Cortex Albiziae 8-16 part, Semen Brassicae Campestris 5-15 part, Pericarpium Citri Reticulatae Viride 5-15 part, Bulbus Fritillariae Cirrhosae 5-15 part, Semen Citri Reticulatae 3-13 part, Semen Persicae 3-13 part, Lignum Sappan 2-8 part, Fructus Citri 2-8 part, Flos Rosae Chinensis 1-5 part.
2. a kind of Chinese medicinal tablet for the treatment of cyclomastopathy according to claim 1, is characterized in that: take off the raw material of Chinese medicine stating weight proportion and be prepared from: Herba Violae 20 parts, Herba Taraxaci 15 parts, Retinervus Luffae Fructus 12 parts, Cortex Albiziae 12 parts, Semen Brassicae Campestris 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Bulbus Fritillariae Cirrhosae 10 parts, Semen Citri Reticulatae 8 parts, 8 parts, Semen Persicae, Lignum Sappan 5 parts, Fructus Citri 5 parts, Flos Rosae Chinensis 3 parts.
3. a preparation method for the Chinese medicinal tablet for the treatment of cyclomastopathy according to claim 1, is characterized in that: step is as follows:
Step one: Retinervus Luffae Fructus is removed impurity and residual seed, beat flat, stripping and slicing, by residual for Semen Persicae removing nucleocapsid and impurity;
Step 2: just Pericarpium Citri Reticulatae Viride remove impurity, cleans, section, after drying, adds its raw material weight 0.1-0.3 rice vinegar doubly and mixes thoroughly, moistening 8-12min;
Step 3: by Semen Citri Reticulatae remove impurity, after cleaning, drying, adding its raw material weight 0.3-0.7 times of mass concentration is that the saline of 5%-10% is mixed thoroughly, moistening 8-12min;
Step 4: by the Retinervus Luffae Fructus of step one, Semen Persicae, the Pericarpium Citri Reticulatae Viride of step 2, the Semen Citri Reticulatae of step 3 is placed in 50 DEG C of pots respectively, and slow fire is fried to yellow, takes out, is crushed to 120 object fine powders after cooling, for subsequent use;
Step 5: by Herba Violae, Herba Taraxaci, Cortex Albiziae, Semen Brassicae Campestris, Bulbus Fritillariae Cirrhosae, Lignum Sappan, Fructus Citri, Flos Rosae Chinensis remove impurity, clean, cutting into slices is placed in marmite, add the water soaking 30-50 minute of raw material weight 3-7 times 15-25 DEG C, then decoct with high heat to boiling, use slow fire instead to continue to decoct 15-35min, filter, leach medicinal residues, obtain filtrate;
Step 6: the extractum filtrate of step 4 being evaporated under 65 DEG C of conditions relative density 1.20, then adds the fine powder that step 5 obtains, mix homogeneously, dries the Chinese medicinal tablet that namely rear tabletted obtains treatment cyclomastopathy for 70 DEG C.
4. a kind of preparation method for the treatment of the Chinese medicinal tablet of cyclomastopathy according to claim 3, is characterized in that: step 2 adds Pericarpium Citri Reticulatae Viride raw material weight 0.15-0.25 rice vinegar doubly and mixes thoroughly, moistening 9-11min.
5. a kind of preparation method for the treatment of the Chinese medicinal tablet of cyclomastopathy according to claim 4, is characterized in that: the rice vinegar that step 2 adds Pericarpium Citri Reticulatae Viride raw material weight 0.2 times is mixed thoroughly, moistening 10min.
6. a kind of preparation method for the treatment of the Chinese medicinal tablet of cyclomastopathy according to claim 3, is characterized in that: it is that the saline of 7%-9% is mixed thoroughly that step 3 adds Semen Citri Reticulatae raw material weight 0.4-0.6 times of mass concentration, moistening 9-11min.
7. a kind of preparation method for the treatment of the Chinese medicinal tablet of cyclomastopathy according to claim 6, is characterized in that: step 3 add Semen Citri Reticulatae raw material weight 0.5 times of mass concentration be 8% saline mix thoroughly, moistening 10min.
8. a kind of preparation method for the treatment of the Chinese medicinal tablet of cyclomastopathy according to claim 3, it is characterized in that: the water soaking 35-45 minute that step slender acanthopanax raw material weight is 4-6 times 18-22 DEG C, then decoct to boiling with high heat, use slow fire instead and continue to decoct 20-30min.
9. a kind of preparation method for the treatment of the Chinese medicinal tablet of cyclomastopathy according to claim 8, is characterized in that: the water soaking that step slender acanthopanax raw material weight is 5 times 20 DEG C 40 minutes, then decocts to boiling with high heat, uses slow fire instead and continues to decoct 25min.
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