CN109248118A - A kind of antiallergic maintenance composition, preparation method and applications - Google Patents
A kind of antiallergic maintenance composition, preparation method and applications Download PDFInfo
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- CN109248118A CN109248118A CN201811089344.9A CN201811089344A CN109248118A CN 109248118 A CN109248118 A CN 109248118A CN 201811089344 A CN201811089344 A CN 201811089344A CN 109248118 A CN109248118 A CN 109248118A
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- extract
- antiallergic
- deionized water
- maintenance composition
- dipotassium glycyrrhizinate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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Abstract
The present invention discloses a kind of antiallergic maintenance composition, by mass percentage, including Roman chamomile (ANTHEMIS NOBILIS) flower extract 1-5%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract 1-5%, sieve bean (PHASEOLUS LUNATUS) seed extract 0.05-0.15%, dipotassium glycyrrhizinate 0.1-0.3%, ceramide 0.5-1.5%, apple (PYRUS MALUS) berry extract 0.5-1.5%, -1 1-5% of oligopeptides, beta glucan 1-5%, surplus are deionized water.The antiallergic maintenance composition is the mixture of eight kinds of functional components, practical function is comprehensive,, maintenance skin barrier antipruritic from instant antiallergic, enhancing skin immunity three approach itself start with and solve the problems, such as antiallergic, can fundamentally enhance the resistivity of fragile type skin itself.
Description
Technical field
The present invention relates to a kind of antiallergic maintenance compositions, preparation method and applications, belong to cosmetic technical field.
Background technique
The rapid development of industrialization and urbanization, incident is the environmental pollution being on the rise, to human health
Increasingly endanger.Skin is the largest organ of direct contact environment pollutant as the barrier between body and environment.Ultraviolet light,
The pollution factors such as dust, exhaust gas will cause skin barrier and be damaged, and natural preventive power weakens, and directly result in skin allergy, dermatitis, skin
The outburst rate of rash etc. increases.
A kind of existing Chinese patent " novel skin antiallergic maintenance composition " (application No. is 201310733808.6), packet
Contain: moisturizer 5%~12%, thickener 0.1%~3.0%, skin-rehabilitating agent 1%~4%, preservative 0.1%~1.5%,
Water surplus.
Chinese patent " a kind of Essence and preparation method thereof of antiallergic maintenance " (application No. is 201711489910.0), packet
Include Astragalus membranacus root extract 0.35-0.5%, Rhizoma Atractylodis Macrocephalae rhizome extract 0.1-0.5%, Tremella fructification extract 1.7-
2.5%, lactobacillus fermentation lysate 0.1-5%, niacinamide 0.5-1%, Sodium Hyaluronate 0.1-0.15%, ceramide
1.0-2.5%, allantoin 0.1-0.3%, 1,3 butanediol 5.0-8.0%, glycerol 2.0-5.0%, Natrulon H-10 1.5-
2.3%, glycerin polyether -26 1-2%, methyl gluceth -201-5%, glyceryl acrylate/acrylic copolymer 1.8-
2.5%, carbomer 0.1-0.25%, parahydroxyacet-ophenone 0.2-0.35%, decoyl hydroximic acid 0.3-0.6%, triethanolamine
0.1-0.25%, surplus are deionized water.
It uses again, Chinese patent " one kind releive antiallergic maintenance ice pellets water " (application No. is 201511029159.7), including ocean
Flos Chrysanthemi extract, glucan, ooze extract, folic acid compound soybean extractive from fermentative, Sodium Polyacrylate graft starch, auxiliary at
Divide and deionized water, the folic acid compound soybean extractive from fermentative are sent out by water, butanediol, 1,2- hexylene glycol, bacillus/soybean
Ferment product extract, folic acid and Sodium Hyaluronate composition.
The research of plant and Chinese herbal medicine antiallergic effect is also being increased year by year both at home and abroad.Such as Kojji K (Anti-
allergic Properties of a Fuit Extract of Prune(prunus domestica L.)in Mite-
Sensitized BALB/c Mice [j] .Food Sci.Technol.Res.2012,18 (5): 755-760) to European plum
Extract has carried out antiallergic research, it is found that it can weaken I type allergic symptom.Akira I(Iwimo A,Inoue A,InoueY,
et al.Anti-allergy effect of strawberry extract[J].Joural of functional
Foods, 2013,5 (4): 1947-1955) etc. researchs discovery Fragaia ananassa Duchesne extract by inhibiting Th2 differentiation to lowering in serum
Ige amount achievees the effect that inhibit specific allergy reaction.King neck (the antipruritic plant society extract preparation process of antiallergic, effect and
Action pathway studies Northeast Agricultural University, 2015) by combination, efficacy assessments etc. filter out with optimal antiallergic, it is antipruritic, repair
Three kinds of natural antiallergic plant society extracts of multiple effect.
Summary of the invention
In view of the above existing problems in the prior art, the present invention provides a kind of antiallergic maintenance compositions, not only allergy flesh
Used in skin, more can fundamentally maintenance skin barrier, enhancing skin immunity, improve fragile type skin, the environment such as haze of being fearless
Pollution.
Invention also provides the preparation method and applications of above-mentioned antiallergic maintenance composition.
To achieve the goals above, a kind of antiallergic maintenance composition that the present invention uses, by mass percentage, including it is white
Flower yellow chamomile (ANTHEMIS NOBILIS) flower extract 1-5%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) are extracted
Object 1-5%, sieve bean (PHASEOLUS LUNATUS) seed extract 0.05-0.15%, dipotassium glycyrrhizinate 0.1-0.3%, nerve
Amide 0.5-1.5%, apple (PYRUS MALUS) berry extract 0.5-1.5%, oligopeptides -1 1-5%, beta glucan 1-5%,
Surplus is deionized water.
As an improvement, the ceramide includes Cer EOS, Cer NP, Cer AP II.
As an improvement, by mass percentage, which includes Roman chamomile (ANTHEMIS
NOBILIS) flower extract 2-4%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract 2-4%, sieve bean
(PHASEOLUS LUNATUS) seed extract 0.08-0.15%, dipotassium glycyrrhizinate 0.2-0.3%, ceramide 0.8-1.2%,
Apple (PYRUS MALUS) berry extract 0.8-1.2%, -1 2-4% of oligopeptides, beta glucan 2-4%, surplus is deionized water.
As an improvement, by mass percentage, including Roman chamomile (ANTHEMIS NOBILIS) flower extract 3%,
Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract 2%, sieve bean (PHASEOLUS LUNATUS) seed extract
0.1%, dipotassium glycyrrhizinate 0.25%, Cer EOS %, apple (PYRUS MALUS) berry extract 1%, oligopeptides -1 3%, β -
Glucan 3%, surplus are the deionized water of cooling after 86.65% high-temperature sterilization.
In addition, the present invention also provides a kind of preparation methods of antiallergic maintenance composition, comprising the following steps:
Deionized water is warming up to 90-100 degrees Celsius by a, and after keeping the temperature disinfection completely in 30 minutes, cooling down is spare；
The dipotassium glycyrrhizinate of formula ratio is add to deionized water by b, and stirring to dipotassium glycyrrhizinate powder is completely dissolved；
C sequentially adds Roman chamomile (ANTHEMIS NOBILIS) flower extract, Asian puccoon (LITHOSPERMUM
ERYTHRORHIZON) extract, sieve bean (PHASEOLUS LUNATUS) seed extract, ceramide, apple (PYRUS
MALUS) berry extract, oligopeptides -1, beta glucan, after being dispersed with stirring uniformly, preparation is completed.
In addition, the application the present invention also provides a kind of antiallergic maintenance composition in cosmetics.
Wherein, the effect of each component that the present invention uses, is respectively as follows:
Roman chamomile (ANTHEMIS NOBILIS) flower extract: instant antiallergic is antipruritic move back it is red；
Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract: anti-inflammatory, antibacterial, cool blood toxin expelling；
Sieve bean (PHASEOLUS LUNATUS) seed extract: antiallergic is anti-inflammatory, elimination is red and swollen, antibacterial anti-inflammatory；
Dipotassium glycyrrhizinate: antibacterial, anti-inflammatory, removing toxic substances, antiallergic；
Ceramide: preventing allergy, and maintenance skin barrier protects skin not encroached on by the external world；
Apple (PYRUS MALUS) berry extract: it is anti-inflammatory, to beat back skin tired out, protect cell；
Oligopeptides -1: epidermal growth factor is damaged the reparation and healing of epidermal cell；
Beta glucan: reinforcing skin immune system itself, and antiallergic is anti-inflammatory, promotes skin after-sun recovery.
Compared with prior art, antiallergic maintenance composition of the invention is the mixture of eight kinds of functional components, practical function
Comprehensively, antipruritic from instant antiallergic, maintenance skin barrier, enhancing skin immunity three approach itself start with and solve the problems, such as antiallergic,
Not only for allergy skin, it more can fundamentally enhance the resistivity of fragile type skin itself.
Specific embodiment
In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention is carried out below further detailed
It describes in detail bright.However, it should be understood that the specific embodiments described herein are merely illustrative of the present invention, it is not limited to this hair
Bright range.
Unless otherwise defined, all technical terms and scientific terms used herein are led with technology of the invention is belonged to
The normally understood meaning of the technical staff in domain is identical, and term as used herein in the specification of the present invention is intended merely to retouch
State the purpose of specific embodiment, it is not intended that in the limitation present invention.
Embodiment 1
A kind of antiallergic maintenance composition, by mass percentage, including Roman chamomile (ANTHEMIS NOBILIS) flower
Extract 1%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract 1%, sieve bean (PHASEOLUS LUNATUS)
Seed extract 0.05%, dipotassium glycyrrhizinate 0.1%, (Cer EOS, Cer NP, Cer AP II are with any for ceramide
Than mixing) 0.5%, apple (PYRUS MALUS) berry extract 0.5%, oligopeptides -1 1%, beta glucan 1%, surplus is high temperature
Cooling deionized water after disinfection；
The preparation method of above-mentioned antiallergic maintenance composition, specifically includes the following steps:
Deionized water is warming up to 90 degrees Celsius by a, and after keeping the temperature disinfection completely in 30 minutes, cooling down is spare；
The dipotassium glycyrrhizinate of formula ratio is add to deionized water by b, and stirring to dipotassium glycyrrhizinate powder is completely dissolved；
C sequentially adds Roman chamomile (ANTHEMIS NOBILIS) flower extract, Asian puccoon (LITHOSPERMUM
ERYTHRORHIZON) extract, sieve bean (PHASEOLUS LUNATUS) seed extract, ceramide, apple (PYRUS
MALUS) berry extract, oligopeptides -1, beta glucan, after being dispersed with stirring uniformly, preparation is completed.
Embodiment 2
A kind of antiallergic maintenance composition, by mass percentage, including Roman chamomile (ANTHEMIS NOBILIS) flower
Extract 5%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract 5%, sieve bean (PHASEOLUS LUNATUS)
Seed extract 0.15%, dipotassium glycyrrhizinate 0.3%, ceramide (including Cer EOS, Cer NP, Cer AP II)
1.5%, apple (PYRUS MALUS) berry extract 1.5%, oligopeptides -1 5%, beta glucan 5%, surplus is after high-temperature sterilization
Cooling deionized water；
The preparation method of above-mentioned antiallergic maintenance composition, specifically includes the following steps:
Deionized water is warming up to 95 degrees Celsius by a, and after keeping the temperature disinfection completely in 30 minutes, cooling down is spare；
The dipotassium glycyrrhizinate of formula ratio is add to deionized water by b, and stirring to dipotassium glycyrrhizinate powder is completely dissolved；
C sequentially adds Roman chamomile (ANTHEMIS NOBILIS) flower extract, Asian puccoon (LITHOSPERMUM
ERYTHRORHIZON) extract, sieve bean (PHASEOLUS LUNATUS) seed extract, ceramide, apple (PYRUS
MALUS) berry extract, oligopeptides -1, beta glucan, after being dispersed with stirring uniformly, preparation is completed.
Embodiment 3
A kind of antiallergic maintenance composition, by mass percentage, including Roman chamomile (ANTHEMIS NOBILIS) flower
Extract 3%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract 2%, sieve bean (PHASEOLUS LUNATUS)
Seed extract 0.1%, dipotassium glycyrrhizinate 0.25%, Cer EOS %, apple (PYRUS MALUS) berry extract 1%, oligopeptides-
1 3%, beta glucan 3%, surplus is the deionized water of cooling after high-temperature sterilization；
The preparation method of above-mentioned antiallergic maintenance composition, specifically includes the following steps:
Deionized water is warming up to 100 degrees Celsius by a, and after keeping the temperature disinfection completely in 30 minutes, cooling down is spare；
The dipotassium glycyrrhizinate of formula ratio is add to deionized water by b, and stirring to dipotassium glycyrrhizinate powder is completely dissolved；
C sequentially adds Roman chamomile (ANTHEMIS NOBILIS) flower extract, Asian puccoon of formula ratio
(LITHOSPERMUM ERYTHRORHIZON) extract, sieve bean (PHASEOLUS LUNATUS) seed extract, neural acyl
Amine, apple (PYRUS MALUS) berry extract, oligopeptides -1, beta glucan, after being dispersed with stirring uniformly, preparation is completed.
Embodiment 4
A kind of antiallergic maintenance composition, by mass percentage, including Roman chamomile (ANTHEMIS NOBILIS) flower
Extract 2%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract 4%, sieve bean (PHASEOLUS LUNATUS)
Seed extract 0.15%, dipotassium glycyrrhizinate 0.2%, Cer EOS .2%, apple (PYRUS MALUS) berry extract 1.2%,
Oligopeptides -1 2%, beta glucan 3%, surplus are the deionized water of cooling after high-temperature sterilization.
The preparation method of above-mentioned antiallergic maintenance composition, specifically includes the following steps:
Deionized water is warming up to 94 degrees Celsius by a, and after keeping the temperature disinfection completely in 30 minutes, cooling down is spare；
The dipotassium glycyrrhizinate of formula ratio is add to deionized water by b, and stirring to dipotassium glycyrrhizinate powder is completely dissolved；
C sequentially adds Roman chamomile (ANTHEMIS NOBILIS) flower extract, Asian puccoon (LITHOSPERMUM
ERYTHRORHIZON) extract, sieve bean (PHASEOLUS LUNATUS) seed extract, ceramide, apple (PYRUS
MALUS) berry extract, oligopeptides -1, beta glucan, after being dispersed with stirring uniformly, preparation is completed.
Antiallergic maintenance composition is made to above-described embodiment, at 24-28 DEG C, humidity is 80% hereinafter, laboratory clean grade
Do not belong to general area, the environment for doing microorganism detection is to carry out performance detection on superclean bench.Specific testing result such as following table
Shown in 1.
The performance of the obtained antiallergic maintenance composition of 1 present invention of table
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modification, equivalent replacement or improvement etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (6)
1. a kind of antiallergic maintenance composition, which is characterized in that by mass percentage, including Roman chamomile (ANTHEMIS
NOBILIS) flower extract 1-5%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract 1-5%, sieve bean
(PHASEOLUS LUNATUS) seed extract 0.05-0.15%, dipotassium glycyrrhizinate 0.1-0.3%, ceramide 0.5-1.5%,
Apple (PYRUS MALUS) berry extract 0.5-1.5%, -1 1-5% of oligopeptides, beta glucan 1-5%, surplus is deionized water.
2. a kind of antiallergic maintenance composition according to claim 1, which is characterized in that the ceramide includes nerve
Amide 1, Cer NP, Cer AP II.
3. a kind of antiallergic maintenance composition according to claim 1, which is characterized in that by mass percentage, including it is white
Flower yellow chamomile (ANTHEMIS NOBILIS) flower extract 2-4%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) are extracted
Object 2-4%, sieve bean (PHASEOLUS LUNATUS) seed extract 0.08-0.15%, dipotassium glycyrrhizinate 0.2-0.3%, nerve
Amide 0.8-1.2%, apple (PYRUS MALUS) berry extract 0.8-1.2%, oligopeptides -1 2-4%, beta glucan 2-4%,
Surplus is deionized water.
4. a kind of antiallergic maintenance composition according to claim 3, which is characterized in that by mass percentage, including it is white
Flower yellow chamomile (ANTHEMIS NOBILIS) flower extract 3%, Asian puccoon (LITHOSPERMUM ERYTHRORHIZON) extract
2%, sieve bean (PHASEOLUS LUNATUS) seed extract 0.1%, dipotassium glycyrrhizinate 0.25%, Cer EOS %, apple
(PYRUS MALUS) berry extract 1%, oligopeptides -1 3%, beta glucan 3%, surplus are cooling after 86.65% high-temperature sterilization
Deionized water.
5. a kind of preparation method of any one of claim 1-4 antiallergic maintenance composition, which is characterized in that including following step
It is rapid:
Deionized water is warming up to 90-100 degrees Celsius by a, and after keeping the temperature disinfection completely in 30 minutes, cooling down is spare；
The dipotassium glycyrrhizinate of formula ratio is add to deionized water by b, and stirring to dipotassium glycyrrhizinate powder is completely dissolved；
C sequentially adds Roman chamomile (ANTHEMIS NOBILIS) flower extract, Asian puccoon (LITHOSPERMUM
ERYTHRORHIZON) extract, sieve bean (PHASEOLUS LUNATUS) seed extract, ceramide, apple (PYRUS
MALUS) berry extract, oligopeptides -1, beta glucan, after being dispersed with stirring uniformly, preparation is completed.
6. a kind of application of any one of claim 1-4 antiallergic maintenance composition in cosmetics.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109758391A (en) * | 2018-12-06 | 2019-05-17 | 浙江大学自贡创新中心 | It is a kind of to have effects that the plant composition of antiallergic |
| CN109939018A (en) * | 2019-05-05 | 2019-06-28 | 江西登云健康美业互联有限公司 | A kind of moisture-keeping composition and preparation method thereof of naturally releiving containing ceramide |
| CN110251415A (en) * | 2019-08-01 | 2019-09-20 | 深圳市健翔生物制药有限公司 | A kind of antiallergic reparation facial mask containing polypeptide |
| CN111437223A (en) * | 2020-04-12 | 2020-07-24 | 广州市索柔生物科技有限公司 | Skin care composition with blue light resisting effect and preparation thereof |
| CN114010542A (en) * | 2021-11-08 | 2022-02-08 | 广东桂格日化有限公司 | Repairing lipstick and preparation method thereof |
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| CN107714531A (en) * | 2017-09-26 | 2018-02-23 | 湖南御家化妆品制造有限公司 | Anti-allergy relieving composition and application thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109758391A (en) * | 2018-12-06 | 2019-05-17 | 浙江大学自贡创新中心 | It is a kind of to have effects that the plant composition of antiallergic |
| CN109939018A (en) * | 2019-05-05 | 2019-06-28 | 江西登云健康美业互联有限公司 | A kind of moisture-keeping composition and preparation method thereof of naturally releiving containing ceramide |
| CN110251415A (en) * | 2019-08-01 | 2019-09-20 | 深圳市健翔生物制药有限公司 | A kind of antiallergic reparation facial mask containing polypeptide |
| CN111437223A (en) * | 2020-04-12 | 2020-07-24 | 广州市索柔生物科技有限公司 | Skin care composition with blue light resisting effect and preparation thereof |
| CN114010542A (en) * | 2021-11-08 | 2022-02-08 | 广东桂格日化有限公司 | Repairing lipstick and preparation method thereof |
| CN114010542B (en) * | 2021-11-08 | 2023-07-21 | 广东桂格日化有限公司 | Lip balm and preparation method thereof |
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Application publication date: 20190122 |