CN109232513B - 化合物lithocarpinols及其制备方法和在制备抗肿瘤药物中的应用 - Google Patents
化合物lithocarpinols及其制备方法和在制备抗肿瘤药物中的应用 Download PDFInfo
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- CN109232513B CN109232513B CN201811089673.3A CN201811089673A CN109232513B CN 109232513 B CN109232513 B CN 109232513B CN 201811089673 A CN201811089673 A CN 201811089673A CN 109232513 B CN109232513 B CN 109232513B
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- Prior art keywords
- compound
- litocarpinol
- lithocarpinol
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- ethyl acetate
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- SRCZQMGIVIYBBJ-UHFFFAOYSA-N ethoxyethane;ethyl acetate Chemical compound CCOCC.CCOC(C)=O SRCZQMGIVIYBBJ-UHFFFAOYSA-N 0.000 claims description 6
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Images
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
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CN201811089673.3A CN109232513B (zh) | 2018-09-18 | 2018-09-18 | 化合物lithocarpinols及其制备方法和在制备抗肿瘤药物中的应用 |
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CN112592350B (zh) * | 2020-12-18 | 2022-03-11 | 广东省微生物研究所(广东省微生物分析检测中心) | 聚酮类化合物lithocarpin E-G及其制备方法和应用 |
CN112852647B (zh) * | 2021-02-23 | 2022-06-07 | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 一种适用于拟茎点霉fs508的过表达载体及其构建方法和应用 |
CN114716312B (zh) * | 2022-05-13 | 2023-04-18 | 广东工业大学 | 半日花烷型二萜化合物及其制备方法与应用 |
CN116354899B (zh) * | 2023-03-03 | 2024-02-27 | 西北农林科技大学 | 一种含恶唑环的杂合聚酮化合物及其制备方法和应用 |
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CN108892658A (zh) * | 2018-08-24 | 2018-11-27 | 广东省微生物研究所(广东省微生物分析检测中心) | 化合物lithocarpinol B及其制备方法和在制备抗真菌药物中的应用 |
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CN108892658A (zh) * | 2018-08-24 | 2018-11-27 | 广东省微生物研究所(广东省微生物分析检测中心) | 化合物lithocarpinol B及其制备方法和在制备抗真菌药物中的应用 |
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