CN109224117A - A kind of production method of the bacteria cellulose operation suture thread of antibacterial - Google Patents
A kind of production method of the bacteria cellulose operation suture thread of antibacterial Download PDFInfo
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- CN109224117A CN109224117A CN201811177285.0A CN201811177285A CN109224117A CN 109224117 A CN109224117 A CN 109224117A CN 201811177285 A CN201811177285 A CN 201811177285A CN 109224117 A CN109224117 A CN 109224117A
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- parts
- powder
- bacteria cellulose
- operation suture
- suture thread
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/10—At least partially resorbable materials containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
Abstract
The invention discloses a kind of production methods of the bacteria cellulose operation suture thread of antibacterial, it includes following component in parts by weight: 10-20 parts of honeysuckle powder, 10-20 parts of Fructus Forsythiae powder, 10-20 parts of folium isatidis powder, 10-20 parts of Radix Isatidis powder, 10-20 parts of astragalus membranaceus powder, 10-20 parts of manyleaf meadowure rhizome and root powder, 10-20 parts of viola mandshurica powder, 4-8 parts of aloin of 10-20 parts of dandelion powder, 10-20 parts of motherwort powder, 5-10 parts of the root of Dahurain angelica, 60-70 parts of bacteria cellulose.The invention discloses a kind of anti-infectious bacteria cellulose operation suture threads, can effectively prevent the infection of wound, and can be degraded in vivo, nontoxic to organism without side-effects.Low production cost, it is easily operated, any financial burden of patient is not added.
Description
Technical field
Present invention relates particularly to a kind of production methods of the bacteria cellulose operation suture thread of antibacterial, belong to bio-medical material
Material field.
Background technique
Biomaterial is the diagnosis for tissue and organ, reparation or a kind of High-tech Material for promoting its function,
It is i.e. irreplaceable for replacing, repairing living tissue natural or artificial material, drugs with function.Biomaterial can execute, promote
Or certain function that replacement loses by disease, damage etc., and rejected region cannot be restored.Since the later period nineties, the world is raw
Object material science and technology rapidly develop, even if biomaterial still remains under the overall situation of current global economy depression
Annual 13% rapid growth, has fully demonstrated its powerful vitality and vast potential for future development.Modern medicine forward direction regeneration and
It rebuilds impaired tissue and organ, recovery and promotes the directions such as human body physiological function, personalization and minimally-invasive treatment and develop.
The conventional materials such as traditional abiotic medical metal, macromolecule, bioceramic have been unable to meet the requirement of medical development, biology
Medical material scientific and engineering is faced with new opportunities and challenges.The occupation rate of market in future, bio-medical material may well
Drug will be caught up with.Therefore, clinical application research and the popularization and application for reinforcing bio-medical material, give priority to China's bio-medical
The integrated system that research, exploitation, production, the marketing of material are combined closely is the task of top priority.In fact, country is currently in biology
Important breakthrough progress is had been achieved in terms of Fundamentals of Material Science research, is walked in advanced ranks in the world, but industrialization level is still
Wait improve, industry size is small, development relatively lags behind, and is not met by the actual needs of Medicare health care.In national policy, warp
Under the support energetically of Ji, the industrialized development of China's biomaterial will raise speed.Enterprise should enhance the ability of autonomous innovation, further
The situation by import is solved, while increasing outlet dynamics, realizes spanning development, expands Chinese biological material product in the world
Influence power.
Biomaterial is widely used, various types, and classification method is also very much.Biomaterial includes metal material (such as alkali
Metal and its alloy etc.), inorganic material (bioactive ceramics, hydroxyapatite etc.) and organic material three categories.Organic material
In mainly macromolecule aggregation material, it is (polyurethane, poly- that high molecular material is usually divided into synthesis high molecular material by material properties
Ester, polylactic acid, polyglycolic acid, lactic acid glycolate copolymer and other medical synthetic plastics and rubber etc.), natural macromolecular material
(such as collagen, silk-fibroin, cellulose, chitosan)；According to the purposes of material, these materials can be divided into biologically inert, life again
Can object activity or biodegradation material by organism metabolism and absorption according to catabolite in high molecular polymer, and degradation-type is high
Molecule can be divided into Bioabsorbable and biological nonabsorable again.According to after material and contacting blood to blood constituent, performance
Influence state be then divided into blood compatible polymer and blood incompatibility.According to material to the compatibility of body cell and instead
Situation is reflected, biocompatibility and bio-incompatibility polymer etc. can be divided into.Wherein, operation suture thread just belongs to biodegradable material
One of material, refers in surgical operation, ligatures Suture hemostasis for wound and organizes one kind of suture is special to use line.
Two classes: nonabsorable line and absorbable thread can be divided into according to its biodegradability.The former has tension intensity height, is easy to sterilize
The low feature of sterilizing, tissue reaction, but it is non-degradable in vivo, so needing to take out stitches after suture, easily bring secondary pain and sense
Dye and scar；The latter can be degraded into soluble product in vivo, be absorbed by the body and gradually excrete it is external, from
And alleviate patient's pain.In clinical application preferably can absorb suture material should meet the following conditions: versatility, aseptic,
Electroless property, without surface tension, without anaphylaxis and non-carcinogenesis, it is easily operated, be unfavorable for bacterial growth, when knotting can ensure that line
Safety is tied without abrasion or cutting, the contraction in tissue can be fought, suture purpose can be absorbed by tissue after reaching and response light
It is micro-.However the common absorbable suture of medical field is mostly catgut, polymer chemistry synthetic thread, there are bio-compatibles when use
Property it is poor, easily cause tissue immunity reaction, absorb insufficient and bad mechanical property the problems such as.It is this at present ideal absorbable
Operation suture thread there is no.And the nonabsorable line for being used to perform the operation, effect are more single.Therefore, it is necessary to further improving and
It improves, develops the operation suture thread that a kind of energy is anti-infectious, can be degraded in vivo.
Bacteria cellulose refer at different conditions, by acetic acid Pseudomonas, Agrobacterium, rhizobium etc. certain is micro-
The general designation of the cellulose of biosynthesis.It has many unique compared with plant cellulose, artificial synthesized bacteria cellulose
Property.
1. bacteria cellulose, without the associations product such as lignin, pectin and hemicellulose, has height compared with plant cellulose
Crystallinity and the high degree of polymerization；
2. hyperfine reticular structure.Bacteria cellulose fibre is to be combined into 40~60 nanometers by 3~4 nanometers of diameter of fento
Thick fibre bundle, and it is intertwined to form flourishing hyperfine network structure；
3. the elasticity modulus of bacteria cellulose is the several times of general plant fiber to ten times or more, and tensile strength is high；
4. bacterial fibers are known as higher biocompatibility, adaptability and good biodegradability；
5. Modulatory character when bacteria cellulose biosynthesis.
Summary of the invention
The purpose of the present invention is to provide a kind of anti-infectious bacteria cellulose operation suture threads.
To achieve the goals above, the present invention provides a kind of anti-infectious bacteria cellulose operation suture threads.Including pressing
According to the following ingredient of weight fraction meter: 10-20 parts of honeysuckle powder, 10-20 parts of Fructus Forsythiae powder, 10-20 parts of folium isatidis powder, Radix Isatidis powder
10-20 parts, 10-20 parts of astragalus membranaceus powder, 10-20 parts of manyleaf meadowure rhizome and root powder, 10-20 parts of 10-20 parts of viola mandshurica powder, dandelion powder aloins
4-8 parts.
Other also include 50-60 parts of bacteria cellulose.
Other also include 10-20 parts of motherwort powder.
Other also include 5-10 parts of the root of Dahurain angelica.
Preparation method are as follows: first activate wood gluconacetobacter, then inoculum concentration according to a certain volume is inoculated with seed liquor
Into culture medium, it is put into stationary culture in incubator.The bacteria cellulose film for then taking out generation, is put into NaOH solution and impregnates
Processing, then with the distilled water flushing of flowing, until the pH of flushing liquor is close to neutral.Obtained bacteria cellulose film is put into mashing
It is polished to obtain paste bacteria cellulose in machine.
Each raw material is weighed in parts by weight to be added in reaction kettle, in ultrasound 3h or more under room temperature, is then heated to 90
DEG C, stir to get blend.Blend is air-dried through extrusion, water cooling, and shearing obtains master batch；Master batch it is heated melt, deaeration and
Spinneret forms primary filament；Again by primary filament under water bath condition secondary drawing, obtain the operation of anti-infectious bacteria cellulose
Suture.
This bacteria cellulose operation suture thread is anti-infective, can effectively prevent the infection of wound, and can be dropped in vivo
Solution.Low production cost, it is easily operated, any financial burden of patient is not added.
Specific embodiment
Embodiment 1
The anti-infectious operation suture thread of the present embodiment, including following component in parts by weight: honeysuckle powder 16
Part, 15 parts of Fructus Forsythiae powder, 10 parts of folium isatidis powder, 10 parts of Radix Isatidis powder, 20 parts of astragalus membranaceus powder, 10 parts of manyleaf meadowure rhizome and root powder, viola mandshurica powder 15
Part, 12 parts of dandelion powder, 4 parts of aloin, 15 parts of motherwort powder, 10 parts of the root of Dahurain angelica, 60 parts of bacteria cellulose.
Embodiment 2
The anti-infectious operation suture thread of the present embodiment, including following component in parts by weight: honeysuckle powder 15
Part, 15 parts of Fructus Forsythiae powder, 10 parts of folium isatidis powder, 12 parts of Radix Isatidis powder, 20 parts of astragalus membranaceus powder, 10 parts of manyleaf meadowure rhizome and root powder, viola mandshurica powder 10
Part, 12 parts of dandelion powder, 4 parts of aloin, 16 parts of motherwort powder, 9 parts of the root of Dahurain angelica, 55 parts of bacteria cellulose.
Embodiment 3
The anti-infectious operation suture thread of the present embodiment, including following component in parts by weight: honeysuckle powder 15
Part, 14 parts of Fructus Forsythiae powder, 10 parts of folium isatidis powder, 12 parts of Radix Isatidis powder, 16 parts of astragalus membranaceus powder, 10 parts of manyleaf meadowure rhizome and root powder, viola mandshurica powder 15
Part, 12 parts of dandelion powder, 4 parts of aloin, 15 parts of motherwort powder, 9 parts of the root of Dahurain angelica, 60 parts of bacteria cellulose.
Embodiment 1
The anti-infectious operation suture thread of the present embodiment, including following component in parts by weight: honeysuckle powder 20
Part, 13 parts of Fructus Forsythiae powder, 10 parts of folium isatidis powder, 10 parts of Radix Isatidis powder, 18 parts of astragalus membranaceus powder, 10 parts of manyleaf meadowure rhizome and root powder, viola mandshurica powder 15
Part, 14 parts of dandelion powder, 6 parts of aloin, 18 parts of motherwort powder, 10 parts of the root of Dahurain angelica, 55 parts of bacteria cellulose.
Natta is a kind of fiber food of low heat value, can be used as healthy food material, the Natta physiology tune being currently known
Solution function includes promoting enterogastric peristalsis, preventing constipation, improve human digestive function etc..Japan studies have shown that Natta has beauty
Hold, the function of weight-reducing.Philippine university research personnel have found that Natta has protective effect on cancer risk, often edible to can be reduced carcinogenic substance to dye
The destruction of colour solid is particularly helpful to the carcinogenic people's air defense cancers such as those contact cigarette, automobile exhaust gases；Heart can also be prevented
Disease makes human immune system from destroying, provides antibacterial lipids.Also there is studies have shown that Natta as a kind of life simultaneously
Object polysaccharide has positive effect to human body cardiovascular disease is prevented also.
Biocompatibility, blood compatibility, safety, the microbic resolvability of this natural polymer of chitosan etc. are excellent
Performance is by all trades and professions extensive concern.Chitosan difficulty is digested and assimilated by human intestines and stomach, and after people takes in them in vivo, they can
Complex compound is generated with lipoid substances such as the triglycerides, fatty acid, bile acid and the cholesterol that are equivalent to sole mass manyfold,
The complex compound is not hydrolyzed by gastric acid, is not digested system absorption, to hinder this substance of absorption of human body, is allowed to wear intestines and cross and arrange
It is external out.Therefore, chitosan class can be reduced foodstuff calories, can be used as food supplement with lipid-loweringing.Agullo etc. studies table
Bright, not only there is very tasty and refreshing sweet taste and conciliation blood pressure, elimination fatty liver, reduction cholesterol and enhancing to exempt from for shell two, three glycan
The function of epidemic disease power, but also there is the water-retaining property and water regulating function for improving food, it can be used as the guarantor of diabetes and obesity
Health food additive.
Claims (4)
1. a kind of bacteria cellulose operation suture thread of antibacterial, it is characterised in that including following component in parts by weight:
10-20 parts of honeysuckle powder, 10-20 parts of Fructus Forsythiae powder, 10-20 parts of folium isatidis powder, 10-20 parts of Radix Isatidis powder, astragalus membranaceus powder 10-20
4-8 parts part, 10-20 parts of manyleaf meadowure rhizome and root powder, 10-20 parts of viola mandshurica powder, 10-20 parts of dandelion powder of aloin.
2. bacteria cellulose operation suture thread according to claim 1, it is characterised in that: other also include bacterial fibers
60-70 parts plain, crystallinity is high, the degree of polymerization is high, tensile strength is high, is easily degraded in vivo.
3. bacteria cellulose operation suture thread according to claim 2, it is characterised in that: it also includes motherwort powder
10-20 parts.
4. bacteria cellulose operation suture thread according to claim 3, it is characterised in that: other also include root of Dahurain angelica 5-10
Part.
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| CN201811177285.0A CN109224117A (en) | 2018-10-11 | 2018-10-11 | A kind of production method of the bacteria cellulose operation suture thread of antibacterial |
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| CN201811177285.0A CN109224117A (en) | 2018-10-11 | 2018-10-11 | A kind of production method of the bacteria cellulose operation suture thread of antibacterial |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110302417A (en) * | 2019-06-18 | 2019-10-08 | 珠海稻田医疗科技有限公司 | A kind of antibacterial, biodegradable suture |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201023919A (en) * | 2008-12-22 | 2010-07-01 | Taiwan Textile Res Inst | Surgical sutures of natural materials and the process for the preparation of the same |
| CN101922064A (en) * | 2010-07-28 | 2010-12-22 | 武汉纺织大学 | Bacterial cellulose and natural polysaccharide blend fiber and preparation method thereof |
| US20130309295A1 (en) * | 2011-02-04 | 2013-11-21 | Paul Gatenholm | Biosynthetic functional cellulose (bc) fibers as surgical sutures and reinforcement of implants and growing tissue |
| CN105251042A (en) * | 2015-10-28 | 2016-01-20 | 钊桂英 | Medical absorbable polyglycolic acid (PGA) operation suture line and preparing method |
| CN105251043A (en) * | 2015-10-28 | 2016-01-20 | 钊桂英 | Medical polylactic acid (PLA) suture line and manufacturing method |
| CN105288716A (en) * | 2015-12-02 | 2016-02-03 | 单县华宇缝合制品有限公司 | Dye for preparing brown catgut capable of quickening wound healing speed |
| CN106012091A (en) * | 2016-07-05 | 2016-10-12 | 盐城工业职业技术学院 | Composite drug-loading fiber for surgical sutures |
| CN106039386A (en) * | 2016-06-16 | 2016-10-26 | 湖州科达化工燃料有限公司 | Anti-infection surgical suture |
| CN106540309A (en) * | 2016-11-25 | 2017-03-29 | 江苏爱西施科技服务咨询股份有限公司 | A kind of fibroin albumen stitching thread with promotion wound healing effect and preparation method thereof |
| CN106729944A (en) * | 2016-11-25 | 2017-05-31 | 江苏爱西施科技服务咨询股份有限公司 | A kind of fibroin albumen suture with easing pain and diminishing inflammation effect and preparation method thereof |
-
2018
- 2018-10-11 CN CN201811177285.0A patent/CN109224117A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201023919A (en) * | 2008-12-22 | 2010-07-01 | Taiwan Textile Res Inst | Surgical sutures of natural materials and the process for the preparation of the same |
| CN101922064A (en) * | 2010-07-28 | 2010-12-22 | 武汉纺织大学 | Bacterial cellulose and natural polysaccharide blend fiber and preparation method thereof |
| US20130309295A1 (en) * | 2011-02-04 | 2013-11-21 | Paul Gatenholm | Biosynthetic functional cellulose (bc) fibers as surgical sutures and reinforcement of implants and growing tissue |
| CN105251042A (en) * | 2015-10-28 | 2016-01-20 | 钊桂英 | Medical absorbable polyglycolic acid (PGA) operation suture line and preparing method |
| CN105251043A (en) * | 2015-10-28 | 2016-01-20 | 钊桂英 | Medical polylactic acid (PLA) suture line and manufacturing method |
| CN105288716A (en) * | 2015-12-02 | 2016-02-03 | 单县华宇缝合制品有限公司 | Dye for preparing brown catgut capable of quickening wound healing speed |
| CN106039386A (en) * | 2016-06-16 | 2016-10-26 | 湖州科达化工燃料有限公司 | Anti-infection surgical suture |
| CN106012091A (en) * | 2016-07-05 | 2016-10-12 | 盐城工业职业技术学院 | Composite drug-loading fiber for surgical sutures |
| CN106540309A (en) * | 2016-11-25 | 2017-03-29 | 江苏爱西施科技服务咨询股份有限公司 | A kind of fibroin albumen stitching thread with promotion wound healing effect and preparation method thereof |
| CN106729944A (en) * | 2016-11-25 | 2017-05-31 | 江苏爱西施科技服务咨询股份有限公司 | A kind of fibroin albumen suture with easing pain and diminishing inflammation effect and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 范子千等: "纳米纤维素研究及应用进展Ⅱ", 《高分子通报》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110302417A (en) * | 2019-06-18 | 2019-10-08 | 珠海稻田医疗科技有限公司 | A kind of antibacterial, biodegradable suture |
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