CN105288716A - Dye for preparing brown catgut capable of quickening wound healing speed - Google Patents
Dye for preparing brown catgut capable of quickening wound healing speed Download PDFInfo
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- CN105288716A CN105288716A CN201510871257.9A CN201510871257A CN105288716A CN 105288716 A CN105288716 A CN 105288716A CN 201510871257 A CN201510871257 A CN 201510871257A CN 105288716 A CN105288716 A CN 105288716A
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Abstract
The invention discloses a dye for preparing brown catgut capable of quickening wound healing speed, belonging to the field of biological sutures. The dye disclosed by the invention is prepared from dichromate, pyrogallic acid, sodium hydrogen sulfite and Chinese herbal medicine's water-extract; the Chinese herbal medicine's water-extract is prepared from swidamacrophylla(Wall.) Sojak, rhizoma phragmitis, pseudobulbus calanthes fimbriatae, eggplant leaf, pteris multifida, folium artemisiae argyi, platycodon grandiflorum, calcined oyster shell, tea tree root, radix angelicae dahuricae, lotus leaf, ramie flower, Chinese violet, siberian nitraria fruit, sophora japonica, rhodiola rosea, pansy, cortex meliae, club bottle gourd fruit, clerodendrum japonicum leaf and water extract of European aspidium and concha arcae. Color components in the dye disclosed by the invention are prepared from the dichromate, the pyrogallic acid and the sodium hydrogen sulfite, bleached sheep intestine is immersed into the dye of the invention, can be rapidly dyed into brown, and is safe and fadeless. The Chinese herbal medicine's water-extract is added into the dye, after a suture line of a catgut is immersed, the Chinese herbal medicinal components are adsorbed on the catgut; the brown catgut prepared by using the dye can promote the healing speed at the suture line, and has the antibacterial efficacy.
Description
Technical field
The present invention relates to biological stitching thread field, particularly a kind of for the preparation of can the dyestuff of brown catgut of accelerating wound speed.
Background technology
The line that the employing silk thread etc. had for the stitching thread of postoperative stitching at present can not be absorbed by the body.Postoperative meeting causes the adverse consequencess such as easy inflammation.The sutural application of Intestinum caprae seu ovis, compensate for above deficiency, and Intestinum caprae seu ovis stitching thread slowly can be absorbed by human body, combines together.
The Chinese invention patent that publication number is " CN1363397A " discloses " a kind of process for preparing medical suture bio-silk from goat intestines ", its description page 2, embodiment 2 second row " uses the hydrogen peroxide bleaching 5 hours of 0.1%; casing is put into the chrome liquor of 0.3 ‰; increase acetate simultaneously and carry out determining chromium " at normal temperatures, wherein, said chrome liquor is used to catgut to dye brown.
The healing rate at Intestinum caprae seu ovis stitching thread suture place of the prior art is not ideal enough, and does not have bacteriostasis.
Summary of the invention
In order to make up above deficiency, the invention provides a kind of make the catgut obtained have bacteriostasis and can increase stitching thread place healing rate for the preparation of can the dyestuff of brown catgut of accelerating wound speed.
Technical scheme of the present invention is:
For the preparation of can the dyestuff of brown catgut of accelerating wound speed, according to weight parts, comprising: 0.001-0.005 part bichromate, 0.05-0.5 part pyrogallic acid, 0.1-1 part sodium sulfite and 80-120 part Chinese traditional medicine water extract, described Chinese traditional medicine water extract is 8-20 part Lai wood root, 3-12 part Rhizoma Phragmitis, 2-8 part pseudobulbus Calanthes fimbriatae, 5-15 part Folium Solani Melongenae, 8-20 part Herba Pteridis multifidae, 5-12 part Folium Artemisiae Argyi, 5-15 part Radix Platycodonis, 3-10 part Concha Ostreae (calcined), 2-6 part Radix Camelliae sinensis, 2-8 part Radix Angelicae Dahuricae, 3-12 part Folium Nelumbinis, 5-15 part ramie flower, 3-10 part Herba Violae, 2-10 part Herba Carlinae biebersteinii, 3-15 part Flos Sophorae, 2-8 part Radix Rhodiolae, 1-6 part Herba Violae Hortensis, 3-10 part Cortex Meliae, 2-8 part Pericarpium Lagenariae hispidae, 2-8 Fen Folium Clerodendri japonici, the Aqueous extracts of 2-5 part european aspidium and 5-15 part Concha Arcae.
Preferably, described bichromate is sodium dichromate or potassium dichromate.
Preferably, the preparation method of described Chinese traditional medicine water extract is: get each Chinese medicinal components according to parts by weight, is crushed to 10-50 order, and then add Chinese medicine gross mass 2-3 water doubly, reflux 1-3 hour, filtering medicinal residues, obtain Chinese traditional medicine water extract.
Preferably, according to weight parts, comprising: 0.002-0.003 part bichromate, 0.08-0.2 part pyrogallic acid, 0.2-0.5 part sodium sulfite and 100 parts of Chinese traditional medicine water extracts.
Wherein:
Lai wood root, sweet, micro-hardship, cool in nature; Heat clearing away suppressing the hyperactive liver, promoting blood circulation and stopping pain; Control headache, laryngopharynx swelling and pain, hypertension, joint aches.
Rhizoma Phragmitis, sweet, cold, attach to the lung and stomach meridians, clearing away heat and promoting production of body fluid, relieving restlessness.
Pseudobulbus Calanthes fimbriatae, acrid in the mouth, hardship, cool in nature; Heat-clearing and toxic substances removing, scattered silt pain relieving; For gastric ulcer, acute gastric dilatation, chronic hepatitis, lumbago, stomachache, lymphoid tuberculosis, chronic pharyngitis, toothache, sand Stranguria, amenorrhea, arthralgia, venom, traumatic injury.
Folium Solani Melongenae, sweet in the mouth, pungent; Property is put down; Loose blood detumescence; Main stranguria with blood; Hematochezia; Dysentery; Discharging fresh blood stool; Carbuncle; Cold injury.
Herba Pteridis multifidae is sweet in the mouth, light, cool in nature; Return liver; Large intestine channel; Clearing away heat-damp and promoting diuresis; Hemostasia and promoting granulation; Removing toxic substances and promoting subsidence of swelling; Cure mainly and have loose bowels; Dysentery; Jaundice; Stranguria; Edema; Hemoptysis; Hematuria; Have blood in stool; Knife injury is hemorrhage; Treating swelling and pain by traumatic injury; Carbuncle sore; Burn due to hot liquid or fire.
Folium Artemisiae Argyi, pungent, bitter, temperature; Return liver,spleen,kidney warp; Dispersing cold for relieving pain, warming the meridian for stopping bleeding; For few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile, spit blood, epistaxis, metrorrhagia through many, gestation hemorrhage; External treatment skin pruritus.
Radix Platycodonis, bitter, pungent, flat; Return lung meridian, lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus.
Concha Ostreae (calcined), salty, be slightly cold; Return liver, gallbladder, kidney channel; Tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving; For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen; Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating; For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Radix Camelliae sinensis is bitter, flat; GUIXIN, kidney channel, heart tonifying diuresis, promoting blood flow to regulate menstruation, heat-clearing and toxic substances removing; Main heart disease, edema, hepatitis, dysmenorrhea, sore swollen toxin, aphtha, herpes zoster, psoriasis etc.。
The Radix Angelicae Dahuricae, pungent, temperature; Return stomach, large intestine, lung meridian; Loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis; For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Folium Nelumbinis is bitter, flat; Return liver, spleen, stomach warp; Clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis; For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood tells nosebleed, metrorrhagia of having blood in stool; Burnt FOLIUM NELUMBINIS astringent therapy removing stasis to stop bleeding; For multiple hemorrhage and puerperal blood faints.
Ramie flower, sweet in the mouth, cold in nature; Clear away heart-fire relieving restlessness; Removing heat from blood rash; Main vexed insomnia; Aphtha of the mouth and tongue; Measles is sent out not smooth thoroughly; Rubella pruritus.
Herba Violae, bitter, acrid, cold; GUIXIN, Liver Channel; Heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling; For furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.
Herba Carlinae biebersteinii, sweet in the mouth, acid, warm in nature, strengthening the spleen and stomach, strengthening by means of tonics, regulating menstruation and activating blood, control asthenic body, deficiency of both QI and blood, incoordination between the spleen and stomach, dyspepsia etc.
Flos Sophorae, bitter, be slightly cold, return liver, large intestine channel; Cooling blood for hemostasis, purging liver-fire.
Radix Rhodiolae, cold in nature, sweet-puckery flavor; Promoting blood circulation and hemostasis, clearing away lung-heat to relieve cough; Control hemoptysis, spitting of blood, pneumonia is coughed, women leucorrhea; Traumatic injury is controlled in external, burn.
Herba Violae Hortensis is bitter, cold; Return lung meridian, heat-clearing and toxic substances removing, cough-relieving.
Cortex Meliae is bitter, cold; Return liver, spleen, stomach warp; Anthelmintic, treats tinea.For ascarid enterobiasis, abdominal pain due to worm stagnation; External treatment scabies pruritus.
Pericarpium Lagenariae hispidae, sweet in the mouth, property are flat, diuretic, heat clearing away, quench the thirst, relieving restlessness; Tonneau water channel, the heat that disappears of quenching the thirst; Main sharp large intestine, moist skin.
Folium Clerodendri japonici, pungent, sweet, flat; Return liver, spleen channel; Dispel the wind, dissipating blood stasis, removing toxic substances and promoting subsidence of swelling; Main migraine, traumatic injury congestive edema, carbuncle sore tumefacting virus.
European aspidium, rhizome is containing secondary pannol, and albaspidin, Filixic Acids, flavaspidic acid and flavaspidic acid BB, 4-butyryl-2-methylphloroglucinol 1-methyl ether etc., have anthelmintic action and antimicrobial effect.
Concha Arcae, salty in the mouth, property is put down; Return lung, stomach, Liver Channel; Expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.
Lai wood root, Rhizoma Phragmitis, pseudobulbus Calanthes fimbriatae, Folium Solani Melongenae, Herba Pteridis multifidae, Folium Artemisiae Argyi, Radix Platycodonis, Concha Ostreae (calcined), Radix Camelliae sinensis, the Radix Angelicae Dahuricae, Folium Nelumbinis, ramie flower, Herba Violae, Herba Carlinae biebersteinii, Flos Sophorae, Radix Rhodiolae, Herba Violae Hortensis, Cortex Meliae, Pericarpium Lagenariae hispidae, Folium Clerodendri japonici, european aspidium and the mutual compatibility of Concha Arcae, play the effect promoting wound healing; Folium Artemisiae Argyi, Cortex Meliae, european aspidium etc. also have bacteriostasis simultaneously.
Beneficial effect of the present invention is:
In dyestuff of the present invention, upper colour content comprises bichromate, pyrogallic acid, sodium sulfite, and the Intestinum caprae seu ovis after bleaching immerses in dyestuff of the present invention, can be dyed to brown fast, and safe, colour-fast.
Add traditional Chinese medicine liquid in dyestuff of the present invention, after Intestinum caprae seu ovis stitching thread immerses, Chinese medicine ingredients is attracted on catgut; Use the brown catgut of preparation of dyestuff of the present invention can promote stitching thread place healing rate, and there is bacteriostasis efficacy.
Detailed description of the invention
Embodiment 1
For the preparation of can the dyestuff of brown catgut of accelerating wound speed, comprising: 0.003kg sodium dichromate, 0.2kg pyrogallic acid, 0.5kg sodium sulfite and 100kg Chinese traditional medicine water extract; Described Chinese traditional medicine water extract is the Aqueous extracts of 14kg Lai wood root, 8kg Rhizoma Phragmitis, 5kg pseudobulbus Calanthes fimbriatae, 10kg Folium Solani Melongenae, 14kg Herba Pteridis multifidae, 8kg Folium Artemisiae Argyi, 10kg Radix Platycodonis, 6kg Concha Ostreae (calcined), 4kg Radix Camelliae sinensis, the 5kg Radix Angelicae Dahuricae, 8kg Folium Nelumbinis, 10kg ramie flower, 7kg Herba Violae, 6kg Herba Carlinae biebersteinii, 9kg Flos Sophorae, 5kg Radix Rhodiolae, 4kg Herba Violae Hortensis, 7kg Cortex Meliae, 5kg Pericarpium Lagenariae hispidae, 5kg Folium Clerodendri japonici, 3kg european aspidium and 10kg Concha Arcae.
The preparation method of described Chinese traditional medicine water extract is: get each Chinese medicinal components according to weight, is crushed to 30 orders, then adds the water of Chinese medicine gross mass 2.5 times, and reflux 2 hours, filtering medicinal residues, obtain Chinese traditional medicine water extract.
Sodium dichromate, pyrogallic acid and sodium sulfite are dispersed in Chinese traditional medicine water extract and namely obtain dyestuff of the present invention.
Embodiment 2
For the preparation of can the dyestuff of brown catgut of accelerating wound speed, comprising: 0.001kg sodium dichromate, 0.5kg pyrogallic acid, 0.1kg sodium sulfite and 120kg Chinese traditional medicine water extract; Described Chinese traditional medicine water extract is the Aqueous extracts of 20kg Lai wood root, 3kg Rhizoma Phragmitis, 8kg pseudobulbus Calanthes fimbriatae, 15kg Folium Solani Melongenae, 8kg Herba Pteridis multifidae, 12kg Folium Artemisiae Argyi, 5kg Radix Platycodonis, 10kg Concha Ostreae (calcined), 2kg Radix Camelliae sinensis, the 8kg Radix Angelicae Dahuricae, 3kg Folium Nelumbinis, 15kg ramie flower, 3kg Herba Violae, 10kg Herba Carlinae biebersteinii, 3kg Flos Sophorae, 8kg Radix Rhodiolae, 1kg Herba Violae Hortensis, 10kg Cortex Meliae, 2kg Pericarpium Lagenariae hispidae, 8kg Folium Clerodendri japonici, 2kg european aspidium and 15kg Concha Arcae.
The preparation method of described Chinese traditional medicine water extract is: get each Chinese medicinal components according to weight, is crushed to 50 orders, then adds the water of Chinese medicine gross mass 3 times, and reflux 3 hours, filtering medicinal residues, obtain Chinese traditional medicine water extract.
Sodium dichromate, pyrogallic acid and sodium sulfite are dispersed in Chinese traditional medicine water extract and namely obtain dyestuff of the present invention.
Embodiment 3
For the preparation of can the dyestuff of brown catgut of accelerating wound speed, comprising: 0.005kg sodium dichromate, 0.05kg pyrogallic acid, 1kg sodium sulfite and 80kg Chinese traditional medicine water extract; Described Chinese traditional medicine water extract is the Aqueous extracts of 8kg Lai wood root, 12kg Rhizoma Phragmitis, 2kg pseudobulbus Calanthes fimbriatae, 15kg Folium Solani Melongenae, 8kg Herba Pteridis multifidae, 5kg Folium Artemisiae Argyi, 15kg Radix Platycodonis, 3kg Concha Ostreae (calcined), 6kg Radix Camelliae sinensis, the 2kg Radix Angelicae Dahuricae, 12kg Folium Nelumbinis, 5kg ramie flower, 10kg Herba Violae, 10kg Herba Carlinae biebersteinii, 15kg Flos Sophorae, 2kg Radix Rhodiolae, 6kg Herba Violae Hortensis, 3kg Cortex Meliae, 8kg Pericarpium Lagenariae hispidae, 2kg Folium Clerodendri japonici, 5kg european aspidium and 5kg Concha Arcae.
The preparation method of described Chinese traditional medicine water extract is: get each Chinese medicinal components according to weight, is crushed to 10 orders, then adds the water of Chinese medicine gross mass 2 times, and reflux 2 hours, filtering medicinal residues, obtain Chinese traditional medicine water extract.
Sodium dichromate, pyrogallic acid and sodium sulfite are dispersed in Chinese traditional medicine water extract and namely obtain dyestuff of the present invention.
Embodiment 4
For the preparation of can the dyestuff of brown catgut of accelerating wound speed, comprising: 0.002kg sodium dichromate, 0.15kg pyrogallic acid, 0.3kg sodium sulfite and 100kg Chinese traditional medicine water extract; Described Chinese traditional medicine water extract is the Aqueous extracts of 14kg Lai wood root, 8kg Rhizoma Phragmitis, 5kg pseudobulbus Calanthes fimbriatae, 10kg Folium Solani Melongenae, 14kg Herba Pteridis multifidae, 8kg Folium Artemisiae Argyi, 10kg Radix Platycodonis, 6kg Concha Ostreae (calcined), 4kg Radix Camelliae sinensis, the 5kg Radix Angelicae Dahuricae, 8kg Folium Nelumbinis, 10kg ramie flower, 5kg Herba Violae, 6kg Herba Carlinae biebersteinii, 9kg Flos Sophorae, 5kg Radix Rhodiolae, 3kg Herba Violae Hortensis, 7kg Cortex Meliae, 5kg Pericarpium Lagenariae hispidae, 5kg Folium Clerodendri japonici, 3kg european aspidium and 8kg Concha Arcae.
The preparation method of described Chinese traditional medicine water extract is: get each Chinese medicinal components according to weight, is crushed to 10 orders, then adds the water of Chinese medicine gross mass 2 times, and reflux 2 hours, filtering medicinal residues, obtain Chinese traditional medicine water extract.
Sodium dichromate, pyrogallic acid and sodium sulfite are dispersed in Chinese traditional medicine water extract and namely obtain dyestuff of the present invention.
Comparative example 1
For the preparation of can the dyestuff of brown catgut of accelerating wound speed, comprising: 0.003kg sodium dichromate, 0.2kg pyrogallic acid, 0.5kg sodium sulfite and 100kg water;
Sodium dichromate, pyrogallic acid and sodium sulfite are dispersed in the dyestuff namely obtaining this comparative example in water.
Clinical practice example
Liu, female, 38 years old, sews up after gastric operation, and half adopts the embodiment of the present invention 1 gained dyestuff to soak the Intestinum caprae seu ovis suture obtained, and second half adopts comparative example 1 gained dyestuff to soak the Intestinum caprae seu ovis suture obtained; Namely the former heal and inflammation or pruritus situation do not occur for 15 days; The latter 20 talent healing, and slightly scratchiness.
Claims (4)
1. one kind for the preparation of can the dyestuff of brown catgut of accelerating wound speed, it is characterized in that, according to weight parts, comprising: 0.001-0.005 part bichromate, 0.05-0.5 part pyrogallic acid, 0.1-1 part sodium sulfite and 80-120 part Chinese traditional medicine water extract, described Chinese traditional medicine water extract is 8-20 part Lai wood root, 3-12 part Rhizoma Phragmitis, 2-8 part pseudobulbus Calanthes fimbriatae, 5-15 part Folium Solani Melongenae, 8-20 part Herba Pteridis multifidae, 5-12 part Folium Artemisiae Argyi, 5-15 part Radix Platycodonis, 3-10 part Concha Ostreae (calcined), 2-6 part Radix Camelliae sinensis, 2-8 part Radix Angelicae Dahuricae, 3-12 part Folium Nelumbinis, 5-15 part ramie flower, 3-10 part Herba Violae, 2-10 part Herba Carlinae biebersteinii, 3-15 part Flos Sophorae, 2-8 part Radix Rhodiolae, 1-6 part Herba Violae Hortensis, 3-10 part Cortex Meliae, 2-8 part Pericarpium Lagenariae hispidae, 2-8 Fen Folium Clerodendri japonici, the Aqueous extracts of 2-5 part european aspidium and 5-15 part Concha Arcae.
2., as claimed in claim 1 for the preparation of can the dyestuff of brown catgut of accelerating wound speed, it is characterized in that: described bichromate is sodium dichromate or potassium dichromate.
3. as claimed in claim 1 for the preparation of can the dyestuff of brown catgut of accelerating wound speed, it is characterized in that, the preparation method of described Chinese traditional medicine water extract is: get each Chinese medicinal components according to parts by weight, be crushed to 10-50 order, then Chinese medicine gross mass 2-3 water is doubly added, reflux 1-3 hour, filtering medicinal residues, obtain Chinese traditional medicine water extract.
4. as claimed in claim 1 for the preparation of can the dyestuff of brown catgut of accelerating wound speed, it is characterized in that, according to weight parts, comprising: 0.002-0.003 part bichromate, 0.08-0.2 part pyrogallic acid, 0.2-0.5 part sodium sulfite and 100 parts of Chinese traditional medicine water extracts.
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Cited By (3)
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| CN106215224A (en) * | 2016-08-29 | 2016-12-14 | 刘畅 | A kind of chrome liquor of chromic suture |
| CN106758370A (en) * | 2017-01-18 | 2017-05-31 | 遵义医学院 | A kind of catgut colouring method |
| CN109224117A (en) * | 2018-10-11 | 2019-01-18 | 天津科技大学 | A kind of production method of the bacteria cellulose operation suture thread of antibacterial |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109224117A (en) * | 2018-10-11 | 2019-01-18 | 天津科技大学 | A kind of production method of the bacteria cellulose operation suture thread of antibacterial |
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Application publication date: 20160203 |