CN106215224A - A kind of chrome liquor of chromic suture - Google Patents

A kind of chrome liquor of chromic suture Download PDF

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Publication number
CN106215224A
CN106215224A CN201610744146.6A CN201610744146A CN106215224A CN 106215224 A CN106215224 A CN 106215224A CN 201610744146 A CN201610744146 A CN 201610744146A CN 106215224 A CN106215224 A CN 106215224A
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CN
China
Prior art keywords
parts
chinese medicine
chrome liquor
herba
water
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Pending
Application number
CN201610744146.6A
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Chinese (zh)
Inventor
刘畅
程庭润
程光起
王凤云
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Liu Chang International Co Ltd
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Priority to CN201610744146.6A priority Critical patent/CN106215224A/en
Publication of CN106215224A publication Critical patent/CN106215224A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06At least partially resorbable materials
    • A61L17/08At least partially resorbable materials of animal origin, e.g. catgut, collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/005Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/14Post-treatment to improve physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418Agents promoting blood coagulation, blood-clotting agents, embolising agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to biological stitching thread field, particularly to the chrome liquor of a kind of chromic suture.The chrome liquor of this chromic suture, including following parts by weighbf component: chrome liquor 100 150 parts, infanticide acid solution 100 200 parts, Chinese medicine extraction liquid 50 80 parts;Described Chinese medicine extraction liquid includes following parts by weight Chinese medicine: Radix Notoginseng 10 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 10 20 parts, Flos Lonicerae 8 15 parts, Herba Pteridis Ensiformis 8 15 parts, Herba Psychotriae Siamicae 8 15 parts, Semen Phaseoli 8 15 parts, Cortex Albiziae 8 15 parts;The chromicized catgut color and luster Lycoperdon polymorphum Vitt using the present invention to produce is shinny, tension stress intensity enhancing, absorbs cycle stretch-out about 67 days.It addition, the Chinese medicine ingredients such as Radix Notoginseng in immersion, Pseudobulbus Bletillae (Rhizoma Bletillae) has preferable hemostatic function in the stitch, can preferably reduce the probability of wound infection, inflammation.

Description

A kind of chrome liquor of chromic suture
(1) technical field
The invention belongs to biological stitching thread field, particularly to the chrome liquor of a kind of chromic suture.
(2) background technology
Since the eighties, domestic Surgical Absorbable Suture (medical catgut) generally applicable in clinical operation, at hands Can become in art stitching thread series and outshine others, absorb the cycle for improving catgut, people are usually by catgut production process Soaking through chrome liquor, the chromic suture so made is longer than flat catgut processed absorbs the cycle.But due to chrome liquor formula, proportioning and Leaching time length is different, and most of chromicized catgut performance indications are not the most preferable, otherwise color sends out crow, does not has gloss;Otherwise Force intensity is inadequate, absorbs and has the shortcomings such as residual, chromium compounds exceed standard.Under this background, the chromium that a kind of chromic suture is new is researched and developed Liquid making method is the most necessary, it is important to how to realize formula and the reasonable mixture ratio of chrome liquor.
(3) summary of the invention
The present invention is in order to make up the deficiencies in the prior art, it is provided that the chrome liquor of a kind of chromic suture.
The present invention is achieved through the following technical solutions:
A kind of chrome liquor of chromic suture, it is characterised in that: include following parts by weighbf component: chrome liquor 100-150 part, gallate-based Liquid 100-200 part, Chinese medicine extraction liquid 50-80 part;Described Chinese medicine extraction liquid includes following parts by weight Chinese medicine: Radix Notoginseng 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 part, Flos Lonicerae 8-15 part, Herba Pteridis Ensiformis 8-15 part, Herba Psychotriae Siamicae 8-15 part, Semen Phaseoli 8-15 part, Cortex Albiziae 8-15 part.
Described chrome liquor is sodium dichromate aqueous solutio, adds 2000 grammes per square metre sodium chromates in every 1000KG water.
Infanticide acid solution is gallate-based aqueous solution, adds 300 grams of gallate-baseds in every 1000KG water.
The preparation method of Chinese medicine extraction liquid is: by Radix Notoginseng, Pseudobulbus Bletillae (Rhizoma Bletillae), Flos Lonicerae, Herba Pteridis Ensiformis, Herba Psychotriae Siamicae, Semen Phaseoli, Cortex Albiziae Adding the water of Chinese medicine gross mass 2-3 times, filter after decocting 30min, filtrate is standby;Add Chinese medicine gross mass 2-3 times Water, filters after decocting 30min, and filtrate is standby;The volume of half it is concentrated into after 2 filtrates being merged.
Further, the chrome liquor of chromic suture includes following parts by weighbf component: chrome liquor 120 parts, infanticide acid solution 120 parts, Chinese medicine extraction liquid 65 parts.
Above-mentioned Chinese medicine extraction liquid of stating includes following parts by weight Chinese medicine: Radix Notoginseng 18 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 18 parts, Flos Lonicerae 10 parts, phoenix Hat grass 10 parts, Herba Psychotriae Siamicae 10 parts, Semen Phaseoli 10 parts, Cortex Albiziae 10 parts.
Catgut is immersed in the present invention, soak about 200 meters casing about 5 hours, catgut is fully infiltrated, every 1 Hour hanging and to air-dry 15min, then infiltrate, repeat the above steps is until chromium system completes.
The invention has the beneficial effects as follows: the chromicized catgut color and luster Lycoperdon polymorphum Vitt using the present invention to produce is shinny, tension stress intensity increases By force, cycle stretch-out is absorbed about 6-7 days.It addition, the Chinese medicine ingredients such as Radix Notoginseng in immersion, Pseudobulbus Bletillae (Rhizoma Bletillae) has merit of preferably stopping blooding in the stitch Can, can preferably reduce the probability of wound infection, inflammation.
(4) detailed description of the invention
Embodiment 1:
Weigh Radix Notoginseng 10kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 10kg, Flos Lonicerae 8kg, Herba Pteridis Ensiformis 8kg, Herba Psychotriae Siamicae 8kg, Semen Phaseoli 8kg, Cortex Albiziae 8kg add Entering the water of Chinese medicine gross mass 2-3 times, filter after decocting 30min, filtrate is standby;Add the water of Chinese medicine gross mass 2-3 times, Filtering after decocting 30min, filtrate is standby;The volume of half it is concentrated into after 2 filtrates being merged.
Configuration sodium dichromate aqueous solutio (adding 2000 grammes per square metre sodium chromates in every 1000KG water), and gallate-based aqueous solution (every 1000KG water adds 300 grams of gallate-baseds);Taking chrome liquor 100kg, infanticide acid solution 100kg, Chinese medicine extraction liquid 50kg is configured to The chrome liquor of chromic suture of the present invention.
Embodiment 2:
Weigh Radix Notoginseng 20kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 20kg, Flos Lonicerae 15kg, Herba Pteridis Ensiformis 15kg, Herba Psychotriae Siamicae 15kg, Semen Phaseoli 15kg, Cortex Albiziae 15kg adds the water of Chinese medicine gross mass 2-3 times, filters after decocting 30min, and filtrate is standby;Add Chinese medicine gross mass 2-3 Water again, filters after decocting 30min, and filtrate is standby;The volume of half it is concentrated into after 2 filtrates being merged.
Configuration sodium dichromate aqueous solutio (adding 2000 grammes per square metre sodium chromates in every 1000KG water), and gallate-based aqueous solution (every 1000KG water adds 300 grams of gallate-baseds);Taking chrome liquor 150kg, infanticide acid solution 200kg, Chinese medicine extraction liquid 80kg is configured to The chrome liquor of chromic suture of the present invention.
Embodiment 3:
Weigh Radix Notoginseng 18kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 18kg, Flos Lonicerae 10kg, Herba Pteridis Ensiformis 10kg, Herba Psychotriae Siamicae 10kg, Semen Phaseoli 10kg, Cortex Albiziae 10kg adds the water of Chinese medicine gross mass 2-3 times, filters after decocting 30min, and filtrate is standby;Add Chinese medicine gross mass 2-3 Water again, filters after decocting 30min, and filtrate is standby;The volume of half it is concentrated into after 2 filtrates being merged.
Configuration sodium dichromate aqueous solutio (adding 2000 grammes per square metre sodium chromates in every 1000KG water), and gallate-based aqueous solution (every 1000KG water adds 300 grams of gallate-baseds);Taking chrome liquor 120kg, infanticide acid solution 120kg, Chinese medicine extraction liquid 65kg is configured to The chrome liquor of chromic suture of the present invention.
The present invention illustrates detailed process equipment and the technological process of the present invention by above-mentioned case study on implementation, but the present invention is also It is not limited only to above-mentioned detailed process equipment and technological process, does not i.e. mean that the present invention has to rely on above-mentioned detailed process equipment Could implement with technological process.Described those skilled in the art are it will be clearly understood that any improvement in the present invention, to the present invention The equivalence of each raw material of product is replaced and the interpolation of auxiliary element, concrete way choice etc., all falls within protection scope of the present invention Within the scope of disclosure.

Claims (6)

1. the chrome liquor of a chromic suture, it is characterised in that: include following parts by weighbf component: chrome liquor 100-150 part, infanticide Acid solution 100-200 part, Chinese medicine extraction liquid 50-80 part;Described Chinese medicine extraction liquid includes following parts by weight Chinese medicine: Radix Notoginseng 10-20 Part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 part, Flos Lonicerae 8-15 part, Herba Pteridis Ensiformis 8-15 part, Herba Psychotriae Siamicae 8-15 part, Semen Phaseoli 8-15 part, Cortex Albiziae 8-15 Part.
The chrome liquor of chromic suture the most according to claim 1, it is characterised in that: described chrome liquor is that sodium dichromate is water-soluble Liquid, adds 2000 grammes per square metre sodium chromates in every 1000KG water.
The chrome liquor of chromic suture the most according to claim 1, it is characterised in that: infanticide acid solution is gallate-based aqueous solution, Every 1000KG water adds 300 grams of gallate-baseds.
The chrome liquor of chromic suture the most according to claim 1, it is characterised in that: by Radix Notoginseng, Pseudobulbus Bletillae (Rhizoma Bletillae), Flos Lonicerae, phoenix coronet Grass, Herba Psychotriae Siamicae, Semen Phaseoli, the water of Cortex Albiziae addition Chinese medicine gross mass 2-3 times, filter after decocting 30min, and filtrate is standby;Again Adding the water of Chinese medicine gross mass 2-3 times, filter after decocting 30min, filtrate is standby;It is concentrated into half after 2 filtrates being merged Volume.
The chrome liquor of chromic suture the most according to claim 1, it is characterised in that: include following parts by weighbf component: chromium Liquid 120 parts, infanticide acid solution 120 parts, Chinese medicine extraction liquid 65 parts.
The chrome liquor of chromic suture the most according to claim 5, it is characterised in that: described Chinese medicine extraction liquid includes following heavy Amount number Chinese medicine: Radix Notoginseng 18 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 18 parts, Flos Lonicerae 10 parts, Herba Pteridis Ensiformis 10 parts, Herba Psychotriae Siamicae 10 parts, Semen Phaseoli 10 parts, Herba Albiziae Skin 10 parts.
CN201610744146.6A 2016-08-29 2016-08-29 A kind of chrome liquor of chromic suture Pending CN106215224A (en)

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Application Number Priority Date Filing Date Title
CN201610744146.6A CN106215224A (en) 2016-08-29 2016-08-29 A kind of chrome liquor of chromic suture

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Application Number Priority Date Filing Date Title
CN201610744146.6A CN106215224A (en) 2016-08-29 2016-08-29 A kind of chrome liquor of chromic suture

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB886814A (en) * 1958-02-17 1962-01-10 American Cyanamid Co Process of preparing surgical suture
CN101455858A (en) * 2009-01-04 2009-06-17 张玉福 Biology collagen brown medical soft suture-thread manufacture method
CN105288716A (en) * 2015-12-02 2016-02-03 单县华宇缝合制品有限公司 Dye for preparing brown catgut capable of quickening wound healing speed

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB886814A (en) * 1958-02-17 1962-01-10 American Cyanamid Co Process of preparing surgical suture
CN101455858A (en) * 2009-01-04 2009-06-17 张玉福 Biology collagen brown medical soft suture-thread manufacture method
CN105288716A (en) * 2015-12-02 2016-02-03 单县华宇缝合制品有限公司 Dye for preparing brown catgut capable of quickening wound healing speed

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Application publication date: 20161214

RJ01 Rejection of invention patent application after publication