CN103285332A - Pharmaceutical composition for promoting post-operation wound healing - Google Patents
Pharmaceutical composition for promoting post-operation wound healing Download PDFInfo
- Publication number
- CN103285332A CN103285332A CN2013102439343A CN201310243934A CN103285332A CN 103285332 A CN103285332 A CN 103285332A CN 2013102439343 A CN2013102439343 A CN 2013102439343A CN 201310243934 A CN201310243934 A CN 201310243934A CN 103285332 A CN103285332 A CN 103285332A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- pharmaceutical composition
- fructus
- flos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a pharmaceutical composition for promoting post-operation wound healing. The pharmaceutical composition is prepared by the following raw materials: paper mulberry fruit, peucedanum decursivum maxim, herba thlaspis, smilax china, cichorium intybus, sevenlobed yam rhizome, siegesbeckia orientalis, justicia gendarussa, manchurian lilac bark, pterocephalus hookeri heck, nodus nelumbinis rhizomatis, medulla stachyuri, common bombax flower, concha arcae, Chinese mahonia stem, sauropus spatulifolius, white hyacinth bean, loofah sponge, polygonum perfoliatum, semen celosiae, fructus litseae, fructus polygoni orientalis, lysionotius pauciflorus maxim, microcos paniculata, rhizoma panacis japonica, radix stephaniae tetrandrae, flos genkwa, cortex meliae, semen abutili, herba potentillae chinensis, rhododendron molle, geosaurus, limonitum, fructus tsaoko, herba moslae, turmeric, gentiana macrophylla pall, decumbent corydalis tuber, flos campsis, lemna minor, ardisia crenata sim, fimbriate orostachys herb and herba portulacae. The pharmaceutical composition for promoting post-operation wound healing has definite curative effect, allows patients to have strong adaptability, and is suitable for a lot of promotion in clinic.
Description
Technical field
The present invention relates to the operating room nursing field, specifically, relate to a kind of for the pharmaceutical composition that promotes wound healing after operation.
Background technology
If surgical wound surface deal with improperly can take place that wound surface is hemorrhage, infection, pain, healing time are long, vital tissue such as tendon, nerve, exposed bone and cicatrix hyperplasia etc., causes very big misery to the patient, also brings a lot of difficulties to clinical treatment simultaneously.The patient is because body constitution is relatively poor, and the skin healing function is poor, is an importance that influences patient's post-operative recovery.Clinical wound surface processing method commonly used comprises physiotherapy (as microwave, infrared ray, laser etc.), wet packing of drugs, nano silver antibiotic dressing, somatomedin etc. a few days ago, there are many deficiencies in these Therapeutic Method, not obvious etc. as pigmentation, drug allergy, curative effect, all can not effectively promote wound healing and reduce complication.
Summary of the invention
The purpose of this invention is to provide a kind of for the pharmaceutical composition that promotes wound healing after operation.
In order to realize method of the present invention, the invention provides a kind of pharmaceutical composition for the promotion wound healing after operation, it is to be made according to weight portion by following raw material medicaments: 13 parts of Fructus Broussonetiaes, 17 parts of 21 parts of Herba Thlaspiss of RADIX PEUCEDANI, 8 parts of Rhizoma Smilacis Chinensiss, 24 parts of 36 parts of Herba Siegesbeckiaes of 15 parts of Rhizoma Dioscoreae Septemlobaes of Herba Cichorii, 17 parts of Herba Gendarussaes, 41 parts of Cortex Syingae Amurensiss, 37 parts of Herba pterocephali, 28 parts of Nodus Nelumbinis Rhizomatis, 42 parts of Medulla Stachyuri (Medulla Helwingiae)s, 51 parts of Flos Bombacis Malabaricis, 38 parts of Concha Arcaes, 73 parts of Caulis Mahoniaes, 25 parts of Folium Sauropis, 74 parts of Semen Lablab Albums, 93 parts of Retinervus Luffae Fructuss, 52 parts of Herba Polygoni cymosis, 63 parts of Semen Celosiae, 27 parts of Fructus Litseae, 47 parts of Fructus Polygoni Orientaliss, 62 parts of Herba Lysionoti Paucifloris, 71 parts of Folium Microcoris paniculataes, 35 parts of Rhizoma Panacis Japonicis, 35 parts of Radixs Stephaniae Tetrandrae, 45 parts of Flos Genkwas, 56 parts of Cortex Meliaees, 37 parts of Semen Abutili, 49 parts of Herba Potentillae Chinensis, 26 parts of Flos Rhododendri Mollis, 50 parts of Pheretimas, 23 parts of Limonitum, 36 parts of Fructus Tsaokos, 73 parts of Herba Moslaes, 25 parts in Rhizoma Curcumae Longae, 45 parts of Radix Gentianae Macrophyllae, 15 parts of Rhizoma Corydalis Decumbentiss, 25 parts of Flos Campsiss, 35 parts in Herba Spirodelae, 30 parts of Radix Ardisiae Crenataes, 35 parts of Herba Orostachyos, 50 parts of 42 parts of Flos Bombacis Malabaricis and Herba Portulacaes.
Preferably, described pharmaceutical composition can be tablet, buccal tablet, instant or ointment.
Of the present invention clear and definite for the pharmaceutical composition curative effect that promotes wound healing after operation, patient adaptability is strong, is suitable for large-scale popularization clinically.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
Embodiment 1
Take by weighing Fructus Broussonetiae 13 grams, RADIX PEUCEDANI 21 gram Herba Thlaspiss 17 grams, Rhizoma Smilacis Chinensis 8 grams, Herba Cichorii 15 gram Rhizoma Dioscoreae Septemlobaes 36 gram Herba Siegesbeckiaes 24 grams, Herba Gendarussae 17 grams, Cortex Syingae Amurensis 41 grams, Herba pterocephali 37 grams, Nodus Nelumbinis Rhizomatis 28 grams, Medulla Stachyuri (Medulla Helwingiae) 42 grams, Flos Bombacis Malabarici 51 grams, Concha Arcae 38 grams, Caulis Mahoniae 73 grams, Folium Sauropi 25 grams, Semen Lablab Album 74 grams, Retinervus Luffae Fructus 93 grams, Herba Polygoni cymosi 52 grams, Semen Celosiae 63 grams, Fructus Litseae 27 grams, Fructus Polygoni Orientalis 47 grams, Herba Lysionoti Pauciflori 62 grams, Folium Microcoris paniculatae 71 grams, Rhizoma Panacis Japonici 35 grams, Radix Stephaniae Tetrandrae 35 grams, Flos Genkwa 45 grams, Cortex Meliae 56 grams, Semen Abutili 37 grams, Herba Potentillae Chinensis 49 grams, Flos Rhododendri Mollis 26 grams, Pheretima 50 grams, Limonitum 23 grams, Fructus Tsaoko 36 grams, Herba Moslae 73 grams, Rhizoma Curcumae Longae 25 grams, Radix Gentianae Macrophyllae 45 grams, Rhizoma Corydalis Decumbentis 15 grams, Flos Campsis 25 grams, Herba Spirodelae 35 grams, Radix Ardisiae Crenatae 30 grams, Herba Orostachyos 35 grams, Flos Bombacis Malabarici 42 grams and Herba Portulacae 50 grams, pulverize, cross 80 mesh sieves.Add 500 gram vaseline, stir, namely get ointment of the present invention.
Experimental example
Physical data
Select wound after surgery patient 960 examples, male 455 examples, women 505 examples, age 60-89 (average 68.5) year old, first traumatic injury wound surface 324 examples wherein, pressure ulcer 258 examples, operation wound 139 examples, recurrent wound 119 examples, other reasons person 120 examples, the course of disease is generally 2d-4w, average 2.4w.The equal informed consent of patient.Be divided into treatment group 486 example and matched group 474 examples, two groups at convenient comparison such as sex, age, the course of disease, state of an illness scoring there was no significant difference (P＞0.05), has comparability.
Therapeutic Method
The treatment group: to emergency treatment wound and other wound surface in refractory to treatment, at first remove the local necrosis tissue, use iodophor disinfection liquid disinfectant wound surface then, the sterilization back uses the ointment of preparation among the embodiment 1 to treat, and every place wound surface is coating 50 grams evenly, every day 2 times, treat 3 days.Matched group: at first remove the local necrosis tissue, use iodophor disinfection liquid disinfectant wound surface then, make the local exposure of wound surface after the sterilization, by infrared equipment (Shijiazhuang three medical apparatus and instruments company limiteies difficult to understand) irradiation wound surface, smear Soviet Union's skin gel (medical chitosan wound repair gel, the greatly just high section in Wuhan biological medicine company limited) simultaneously, every day 2 times, each wound surface is coating 50 grams evenly, treat 3 days.Observe the patient during the treatment and have or not infection and other untoward reaction, adopt blind method to carry out the healing state evaluation, and according to efficacy assessment standard therapeutic effect is analyzed.
Efficacy assessment standard
Recovery from illness: wound healing, form a scab and come off; Take a turn for the better: transudate reduces, and wound surface dwindles area＞20%, and the degree of depth shoals, no secretions, granulation tissue growth; Invalid: wound surface area and the degree of depth do not have change.Effectively=and recovery from illness+take a turn for the better.
The result
Treatment group fully recover 187 examples, 254 examples that take a turn for the better, invalid 45 examples, total effective rate 90.7%; Matched group fully recover 89 examples, 161 examples that take a turn for the better, invalid 224 examples, total effective rate 52.7%.The total effective rate for the treatment of group is apparently higher than the total effective rate of matched group.Treatment group patient does not see untoward reaction during the medication, yet not recurrence after the healing.Matched group is found 3 routine infection events during treating.
Claims (2)
1. a pharmaceutical composition that is used for promoting wound healing after operation is characterized in that it is to be made according to weight portion by following raw material medicaments: 13 parts of Fructus Broussonetiaes, 17 parts of 21 parts of Herba Thlaspiss of RADIX PEUCEDANI, 8 parts of Rhizoma Smilacis Chinensiss, 24 parts of 36 parts of Herba Siegesbeckiaes of 15 parts of Rhizoma Dioscoreae Septemlobaes of Herba Cichorii, 17 parts of Herba Gendarussaes, 41 parts of Cortex Syingae Amurensiss, 37 parts of Herba pterocephali, 28 parts of Nodus Nelumbinis Rhizomatis, 42 parts of Medulla Stachyuri (Medulla Helwingiae)s, 51 parts of Flos Bombacis Malabaricis, 38 parts of Concha Arcaes, 73 parts of Caulis Mahoniaes, 25 parts of Folium Sauropis, 74 parts of Semen Lablab Albums, 93 parts of Retinervus Luffae Fructuss, 52 parts of Herba Polygoni cymosis, 63 parts of Semen Celosiae, 27 parts of Fructus Litseae, 47 parts of Fructus Polygoni Orientaliss, 62 parts of Herba Lysionoti Paucifloris, 71 parts of Folium Microcoris paniculataes, 35 parts of Rhizoma Panacis Japonicis, 35 parts of Radixs Stephaniae Tetrandrae, 45 parts of Flos Genkwas, 56 parts of Cortex Meliaees, 37 parts of Semen Abutili, 49 parts of Herba Potentillae Chinensis, 26 parts of Flos Rhododendri Mollis, 50 parts of Pheretimas, 23 parts of Limonitum, 36 parts of Fructus Tsaokos, 73 parts of Herba Moslaes, 25 parts in Rhizoma Curcumae Longae, 45 parts of Radix Gentianae Macrophyllae, 15 parts of Rhizoma Corydalis Decumbentiss, 25 parts of Flos Campsiss, 35 parts in Herba Spirodelae, 30 parts of Radix Ardisiae Crenataes, 35 parts of Herba Orostachyos, 50 parts of 42 parts of Flos Bombacis Malabaricis and Herba Portulacaes.
2. according to claim 1 for the pharmaceutical composition that promotes wound healing after operation, it is characterized in that described pharmaceutical composition can be tablet, buccal tablet, instant or ointment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013102439343A CN103285332A (en) | 2013-06-20 | 2013-06-20 | Pharmaceutical composition for promoting post-operation wound healing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013102439343A CN103285332A (en) | 2013-06-20 | 2013-06-20 | Pharmaceutical composition for promoting post-operation wound healing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103285332A true CN103285332A (en) | 2013-09-11 |
Family
ID=49087221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2013102439343A Pending CN103285332A (en) | 2013-06-20 | 2013-06-20 | Pharmaceutical composition for promoting post-operation wound healing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103285332A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751487A (en) * | 2014-01-15 | 2014-04-30 | 薛晓晓 | Traditional Chinese medicine extract used for hand care and preparation method thereof |
| CN105232856A (en) * | 2015-11-16 | 2016-01-13 | 张少峰 | Medicinal composition for postoperative wound healing and application thereof |
| CN105288716A (en) * | 2015-12-02 | 2016-02-03 | 单县华宇缝合制品有限公司 | Dye for preparing brown catgut capable of quickening wound healing speed |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101642486A (en) * | 2009-08-28 | 2010-02-10 | 湖南省中医药研究院 | Chinese herb composition for promoting wound healing and preparation method thereof |
| CN102940854A (en) * | 2012-11-27 | 2013-02-27 | 陈兴旺 | Traditional Chinese medicine composition for facilitating wound healing after surgical operations, preparation process and application |
-
2013
- 2013-06-20 CN CN2013102439343A patent/CN103285332A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101642486A (en) * | 2009-08-28 | 2010-02-10 | 湖南省中医药研究院 | Chinese herb composition for promoting wound healing and preparation method thereof |
| CN102940854A (en) * | 2012-11-27 | 2013-02-27 | 陈兴旺 | Traditional Chinese medicine composition for facilitating wound healing after surgical operations, preparation process and application |
Non-Patent Citations (2)
| Title |
|---|
| 于文会等: "促进大鼠伤口愈合中药组方的筛选", 《东北农业大学学报》 * |
| 雷普登等: "益气活血汤治疗腹部手术后伤口愈合不良32例", 《中国中西医结合外科杂志》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751487A (en) * | 2014-01-15 | 2014-04-30 | 薛晓晓 | Traditional Chinese medicine extract used for hand care and preparation method thereof |
| CN105232856A (en) * | 2015-11-16 | 2016-01-13 | 张少峰 | Medicinal composition for postoperative wound healing and application thereof |
| CN105232856B (en) * | 2015-11-16 | 2018-08-14 | 张少峰 | A kind of pharmaceutical composition and its application for postoperative wound healing |
| CN105288716A (en) * | 2015-12-02 | 2016-02-03 | 单县华宇缝合制品有限公司 | Dye for preparing brown catgut capable of quickening wound healing speed |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103223153A (en) | Medicament for treating femoral head necrosis | |
| CN103285332A (en) | Pharmaceutical composition for promoting post-operation wound healing | |
| CN103566278B (en) | Cortex torricelliae tiliifoliae | |
| CN1085797A (en) | Eliminating inflammation and expelling toxin sore treatment ointment and preparation method thereof | |
| CN102247423B (en) | External-use Chinese herbal medicine compound preparation for accelerating fracture healing | |
| CN103142966A (en) | Medicament for wound healing | |
| CN103550327A (en) | Preparation method of medicament for healing of wound | |
| CN102772617B (en) | Medicine for treating disease of hyperosteogeny | |
| CN103007240A (en) | Medicament for aged wound healing | |
| CN101612203B (en) | Traditional Chinese medicine composition used for treating pointed condyloma and application thereof | |
| CN108685985A (en) | A kind of burns cream and preparation method thereof | |
| CN102579928B (en) | Medicine for treating pulmonary tuberculosis and preparation method | |
| CN101890076B (en) | Traditional Chinese medicine oral preparation for treating sores and ulcers | |
| CN105943584A (en) | Medicine for treating dental ulcer | |
| CN101274047A (en) | External-use ointment for treating burn and method of preparing the same | |
| CN105854071A (en) | Vaginal packing hemostatic material and preparation method thereof | |
| CN104739856B (en) | Application of the montmorillonite external pulvis in the drug for preparing treatment skin ulcer | |
| CN103908501B (en) | A kind of Chinese medicine composition for the treatment of pityriasis rosea | |
| CN106177523A (en) | A kind of medicine treating superficial ulcer | |
| CN102552503A (en) | Traditional Chinese medicine powder used for treating cervical erosion | |
| CN102068471B (en) | Externally applied medicine for treating carbuncle diseases | |
| CN110302356A (en) | A kind of spray for treating bedsore | |
| CN108295178A (en) | Traditional Chinese medicine composition and traditional Chinese medicine ointment for treating refractory wound and preparation method thereof | |
| CN101785783A (en) | Use of metal Ti microparticles in promotion or increase of potency of externally-applied skin antibacterial or sterilizing medicaments | |
| CN108938837A (en) | A kind of pharmaceutical composition and preparation method thereof for treating scald |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20130911 |