CN109182032A - A kind of Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor for alleviating physical fatigue - Google Patents
A kind of Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor for alleviating physical fatigue Download PDFInfo
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Abstract
The present invention relates to a kind of Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquors for alleviating physical fatigue, belong to field of health care wine, the present invention is with Notogineng Extract, Rhizoma Polygonati extract, cornel extractive and Herba Dendrobii extract after certain proportion compatibility with 50 degree of white spirit mixeds to form, and choose different extraction processes respectively according to the characteristic of each raw material, wherein Notogineng Extract and cornel extractive are extracted using alcohol extraction process, Rhizoma Polygonati extract and Herba Dendrobii extract are extracted with extraction process by water, the proportion of each extract are as follows: Notogineng Extract 14~30%, Rhizoma Polygonati extract 20~40%, cornel extractive 10~43%, Herba Dendrobii extract 10~40%, inventive formulation is made of the raw material of integration of drinking and medicinal herbs with the raw material that can be used for health food, health liquor prepared by the present invention, it is fast with absorbing, effect is rapid, quality is stablized, Convenient for taking, the high advantage of bioavilability has apparent alleviation physical fatigue and liver-protecting efficacy.
Description
Technical field
The invention belongs to field of health care wine, specifically, are related to a kind of Radix Notoginseng rhizoma polygonati Fructus Corni stone for alleviating physical fatigue
Dry measure used in former times health liquor.
Background technique
Although the mechanization degree of human lives is higher and higher, intelligent robot etc. is also largely instead of artificial
Labour, but the work having is there is still a need for paying a large amount of manual labor, and the crowd of long campaigns manual labor, there is physical strength mostly
Overdraw, liver kidney deficiency is weak, qi and blood is in debt, or even the symptoms such as overwork hematochezia occurs.
Therefore, it is necessary to provide a kind of with the health liquor for alleviating physical fatigue.
Summary of the invention
Radix Notoginseng: sweet and slightly bitter taste, temperature are passed through blood, enter liver stomach meridian.Dissipating stasis and stanching bleeding, blood circulation and channel invigorating, tool stagnation resolvation are not hurt just, and hemostasis is not
Stay the advantage of the stasis of blood.
Rhizoma polygonati: such as maltosemalt sugar sweet in flavor, mild-natured matter profit enter the warp of lung spleen kidney three.Boosting qi and nourishing yin, moistening lung, invigorating the spleen, kidney-nourishing are three burnt gas
The product of high and level tone benefit.
Fructus Corni: sour matter profit enters liver kidney channel.It tonifies the liver and kidney, arresting collape syndrome by astringents, tepor is not dry, mends without high, Ji Nengyi
Essence, and can be supporing yang, for the key medicine of flat nourishing liver and kidney yin-yang.
Dendrobium nobile: it is sweet in flavor, but shy sedate, bone strengthening qi-restoratives is apt to drive cold numbness.Suitable for febrile disease body fluid is injured or yin asthenia generating intrinsic heat,
And tongue light is without the deficiencies of stomach-Yin disease such as tongue fur, body fluid is few
The present inventor pass through experimental results demonstrate: utilize Radix Notoginseng, rhizoma polygonati, Fructus Corni and Herba Dendrobii extract and white spirit mixed, production
Health liquor, prepared health liquor have apparent alleviation physical fatigue, and strengthen immunity, keeps fit and healthy liver protecting
Effect.
In consideration of it, one of the objects of the present invention is to provide a kind of Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile guarantors for alleviating physical fatigue
Strong wine:
The Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor of the alleviation physical fatigue is by Notogineng Extract, Rhizoma Polygonati extract, mountain
Rutaecarpa extract and Herba Dendrobii extract after certain compatibility with white spirit mixed to form.
Preferably, each extract is prepared as following weight percent: Notogineng Extract 14~30%, rhizoma polygonati extract
Object 20~40%, cornel extractive 10~43%, Herba Dendrobii extract 10~40%.
Another object of the present invention is to provide a kind of Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquors for alleviating physical fatigue
Preparation method, characterized by comprising:
(1) Notogineng Extract is made using alcohol extraction process using Radix Notoginseng as raw material；
(2) Rhizoma Polygonati extract is made using extraction process by water using rhizoma polygonati as raw material；
(3) cornel extractive is made using alcohol extraction process using Fructus Corni as raw material；
(4) Herba Dendrobii extract is made using extraction process by water using dendrobium nobile as raw material；
(5) by said extracted object and 50 degree of white spirit mixeds up to the Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor for alleviating physical fatigue.
Preferably, the preparation of the Notogineng Extract includes the following steps:
(1) Radix Notoginseng powder prepares: will cross 10 meshes after Radix Notoginseng cleaning, dry, smashing；
(2) alcohol extracting three times: being that 85% ethyl alcohol is mixed with the mass ratio of 1:10 by Radix Notoginseng powder and concentration, 90 degree at a temperature of extract 2
Hour, obtain an extracting solution；85% ethyl alcohol will be added with the mass ratio of 1:10 by the Radix Notoginseng powder once extracted, in 90 degree of temperature
Degree is lower to be extracted 1.5 hours, and secondary raffinate is obtained；85% ethyl alcohol is added with the mass ratio of 1:10 in Radix Notoginseng powder Jing Guo second extraction,
90 degree at a temperature of extract 1.0 hours, obtain extracting solution three times；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: it will once extract filtrate, second extraction filtrate and extraction filtrate is concentrated in vacuo respectively three times,
Obtain Notogineng Extract；
(5) extract mixes: by the extract obtained mixing of step (4) to get Notogineng Extract.
Preferably, the preparation of the Rhizoma Polygonati extract includes the following steps:
(1) rhizoma polygonati prepares: raw sealwort being crushed and crosses 10 meshes；
(2) water mentions three times: rhizoma polygonati piece is mixed with distilled water with the mass ratio of 1:10,95 degree at a temperature of extract 1.5 hours,
Obtain an extracting solution；Distilled water will be added with the mass ratio of 1:8 by the rhizoma polygonati that once extracts, 95 degree at a temperature of extract
1.0 hours, obtain secondary raffinate；Distilled water is added with the mass ratio of 1:6 in rhizoma polygonati Jing Guo second extraction, in 95 degree of temperature
It is lower to extract 1.0 hours, obtain extracting solution three times；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: by it is primary extract filtrate, second extraction filtrate and three times extract filtrate respectively 75 DEG C at a temperature of
It is concentrated in vacuo, obtains Rhizoma Polygonati extract；
(5) extract mixes: by the extract obtained mixing of step (4) to get Rhizoma Polygonati extract.
Preferably, the preparation of the cornel extractive includes the following steps:
(1) it crushes: Fructus Corni is crushed and sieved with 100 mesh sieve；
(2) alcohol extracting three times: Fructus Corni point is mixed with 85% ethyl alcohol with the mass ratio of 1:20, in 50 DEG C of temperature, 45Hz supersonic frequency
Ultrasonic-leaching 30min is used under rate, 100W ultrasonic power, obtains first time extracting solution；By by the Fructus Corni powder that once extracts with
85% ethyl alcohol is added in the mass ratio of 1:10, uses ultrasonic-leaching under 50 DEG C of temperature, 45Hz supersonic frequency, 100W ultrasonic power
30min obtains second of extracting solution；85% ethyl alcohol is added with the mass ratio of 1:10 in Fructus Corni powder Jing Guo second extraction, at 50 DEG C
Ultrasonic-leaching 30min is used under temperature, 45Hz supersonic frequency, 100W ultrasonic power, obtains third time extracting solution；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: by it is primary extract filtrate, second extraction filtrate and three times extract filtrate respectively 75 DEG C at a temperature of
It is concentrated in vacuo, obtains cornel extractive；
Preferably, the preparation of the Herba Dendrobii extract includes the following steps:
(1) dendrobium nobile prepares: dendrobium nobile being crushed, 10 meshes are crossed；
(2) water mentions three times: dendrobium nobile piece is mixed with distilled water with the mass ratio of 1:30,90 degree at a temperature of extract 2.0 hours,
Obtain an extracting solution；Distilled water will be added with the mass ratio of 1:20 by the dendrobium nobile that once extracts, 90 degree at a temperature of extract
1.5 hours, obtain secondary raffinate；Distilled water is added with the mass ratio of 1:15 in dendrobium nobile Jing Guo second extraction, in 90 degree of temperature
Degree is lower to be extracted 1.0 hours, and extracting solution three times is obtained；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: by it is primary extract filtrate, second extraction filtrate and three times extract filtrate respectively 75 DEG C at a temperature of
It is concentrated in vacuo, obtains Herba Dendrobii extract；
(5) extract mixes: by the extract obtained mixing of step (4) to get Herba Dendrobii extract.
Beneficial effects of the present invention:
1, the present invention breaks traditional health liquor preparation process, creatively directly prepares health care with extract and white spirit mixed
Wine overcomes the defect that white wine leaching rate is low, soaking time is long, and the effective component extraction rate of raw material is higher；The present invention according to
The characteristic of each drug, different raw materials select different extraction processes, not only further increase effective component, and extraction process
It is more reasonable.
2, the proportion of extract of the invention is obtained most for the purpose of alleviating physical fatigue, by lot of experiment validation
Good compatibility generates good synergistic effect between each extract under the compatibility, and health-care effect becomes apparent from.
3, the raw materials used in the present invention is fallen in lines integration of drinking and medicinal herbs catalogue, and for the healthy food material of safety, production technology meets
Food hygiene related request, it is without any side effects, it can be eaten for a long time.
4, health liquor prepared by the present invention has and absorbs fastly, and rapidly, quality is stablized for effect, convenient for taking, bioavilability
High advantage has effects that significantly to alleviate physical strength.
Specific embodiment
It, below will be to preferred reality of the invention in order to keep the purpose of the present invention, technical scheme and beneficial effects clearer
It applies example to be described in detail, to facilitate the technical staff to understand.
Embodiment 1
The preparation of Notogineng Extract:
(1) Radix Notoginseng powder prepares: will cross 10 meshes after Radix Notoginseng cleaning, dry, smashing；
(2) alcohol extracting three times: being that 85% ethyl alcohol is mixed with the mass ratio of 1:10 by Radix Notoginseng powder and concentration, 90 degree at a temperature of extract 2
Hour, obtain an extracting solution；85% ethyl alcohol will be added with the mass ratio of 1:10 by the Radix Notoginseng powder once extracted, in 90 degree of temperature
Degree is lower to be extracted 1.5 hours, and secondary raffinate is obtained；85% ethyl alcohol is added with the mass ratio of 1:10 in Radix Notoginseng powder Jing Guo second extraction,
90 degree at a temperature of extract 1.0 hours, obtain extracting solution three times；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: will once extract filtrate, second extraction filtrate and extraction filtrate is concentrated in vacuo to respectively three times
Extractive content >=99% obtains Notogineng Extract；
(5) extract mixes: by the extract obtained mixing of step (4) to get Notogineng Extract.
The preparation of Rhizoma Polygonati extract:
(1) rhizoma polygonati prepares: raw sealwort being crushed and crosses 10 meshes；
(2) water mentions three times: rhizoma polygonati piece is mixed with distilled water with the mass ratio of 1:10,95 degree at a temperature of extract 1.5 hours,
Obtain an extracting solution；Distilled water will be added with the mass ratio of 1:8 by the rhizoma polygonati that once extracts, 95 degree at a temperature of extract
1.0 hours, obtain secondary raffinate；Distilled water is added with the mass ratio of 1:6 in rhizoma polygonati Jing Guo second extraction, in 95 degree of temperature
It is lower to extract 1.0 hours, obtain extracting solution three times；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: by it is primary extract filtrate, second extraction filtrate and three times extract filtrate respectively 75 DEG C at a temperature of
It carries out being concentrated in vacuo to extractive content >=99%, obtains Rhizoma Polygonati extract；
(5) extract mixes: by the extract obtained mixing of step (4) to get Rhizoma Polygonati extract.
The preparation of cornel extractive:
(1) it crushes: Fructus Corni is crushed and sieved with 100 mesh sieve；
(2) alcohol extracting three times: Fructus Corni powder is mixed with 85% ethyl alcohol with the mass ratio of 1:20, in 50 DEG C of temperature, 45Hz supersonic frequency
Ultrasonic-leaching 30min is used under rate, 100W ultrasonic power, obtains first time extracting solution；By by the Fructus Corni powder that once extracts with
85% ethyl alcohol is added in the mass ratio of 1:10, uses ultrasonic-leaching under 50 DEG C of temperature, 45Hz supersonic frequency, 100W ultrasonic power
30min obtains second of extracting solution；85% ethyl alcohol is added with the mass ratio of 1:10 in Fructus Corni powder Jing Guo second extraction, at 50 DEG C
Ultrasonic-leaching 30min is used under temperature, 45Hz supersonic frequency, 100W ultrasonic power, obtains third time extracting solution；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: by it is primary extract filtrate, second extraction filtrate and three times extract filtrate respectively 75 DEG C at a temperature of
It carries out being concentrated in vacuo to extractive content >=99%, obtains cornel extractive；
(5) extract mixes: by the extract obtained mixing of step (4) to get cornel extractive.
The preparation of Herba Dendrobii extract:
(1) dendrobium nobile prepares: dendrobium nobile being crushed, 10 meshes are crossed；
(2) water mentions three times: dendrobium nobile piece is mixed with distilled water with the mass ratio of 1:30,90 degree at a temperature of extract 2.0 hours,
Obtain an extracting solution；Distilled water will be added with the mass ratio of 1:20 by the dendrobium nobile that once extracts, 90 degree at a temperature of extract
1.5 hours, obtain secondary raffinate；Distilled water is added with the mass ratio of 1:15 in dendrobium nobile Jing Guo second extraction, in 90 degree of temperature
Degree is lower to be extracted 1.0 hours, and extracting solution three times is obtained；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: by it is primary extract filtrate, second extraction filtrate and three times extract filtrate respectively 75 DEG C at a temperature of
It carries out being concentrated in vacuo to extractive content >=99%, obtains Herba Dendrobii extract；
(5) extract mixes: by the extract obtained mixing of step (4) to get Herba Dendrobii extract.
After Notogineng Extract, Rhizoma Polygonati extract, cornel extractive, Herba Dendrobii extract are mixed with the ratio of 3:4:2:1,
It is dispensed after being mixed with 50 degree of white wine with the mass ratio of 1:6 with 125m food-grade vial.
Embodiment 2:
Produce Radix Notoginseng, rhizoma polygonati, Fructus Corni and Herba Dendrobii extract respectively for method same as Example 1, by Notogineng Extract,
After Rhizoma Polygonati extract, cornel extractive, Herba Dendrobii extract are with the ratio mixing of 2:3:1:3, with 50 degree of white wine with the quality of 1:6
Than being dispensed after mixing with 125m food-grade vial.
Embodiment 3:
Produce Radix Notoginseng, rhizoma polygonati, Fructus Corni and Herba Dendrobii extract respectively for method same as Example 1, by Notogineng Extract,
After Rhizoma Polygonati extract, cornel extractive, Herba Dendrobii extract are with the ratio mixing of 1:2:3:1, with 50 degree of white wine with the quality of 1:6
Than being dispensed after mixing with 125m food-grade vial.
Embodiment 4:
Produce Radix Notoginseng, rhizoma polygonati, Fructus Corni and Herba Dendrobii extract respectively for method same as Example 1, by Notogineng Extract,
After Rhizoma Polygonati extract, cornel extractive, Herba Dendrobii extract are with the ratio mixing of 3:2:1:4, with 50 degree of white wine with the matter of 1:6
Amount after mixing with 125m food-grade vial than being dispensed.
Embodiment 5:
Produce Radix Notoginseng, rhizoma polygonati, Fructus Corni and Herba Dendrobii extract respectively for method same as Example 1, by Notogineng Extract,
After Rhizoma Polygonati extract, cornel extractive, Herba Dendrobii extract are with the ratio mixing of 2:2:1:3, with 50 degree of white wine with the quality of 1:6
Than being dispensed after mixing with 125m food-grade vial.
Alleviate physical fatigue efficacy test one:
50 people of building civilian worker that certain construction site is had a meal in canteen is chosen, is randomly divided into 5 groups, one group of every 10 people drinks respectively
With health liquor in 1~embodiment of embodiment 5, sleeps daily first two hours and drink 30mL, continuously drink 6 months, during test, diet
Situation does not specially require, and tests before testing with after test the physical efficiency of testee, sleep and body weights respectively:
1. physical stamina test situation:
Physical stamina test is carried out to related tested personnel, testing evaluation standard is as shown in table 1.
1 physical stamina test standards of grading of table
Synthetic physical ability score computation method :+0.4*800 meters of chin-up score of 0.2* lung capacity score+0.4*1 minutes are run
Point.It is surveyed before every testee test according to the standards of grading and physical efficiency comprehensive score situation, test result such as 2 institute of table after test
Show:
2 physical stamina test result of table
As can be seen from the above table: the effect of physical efficiency is remarkably reinforced in health liquor prepared by the present invention is particularly suitable for physical labourer
It drinks.
2. sleep and body weights test
The problems such as long campaigns physical labourer often can cause poor sleeping quality, weight to lighten because of impaired body function,
Sleep quality and weight test have been carried out to above-mentioned subject person.
According to the sleep situation of testee, night dream situation and after feeling, three aspects of mental status are commented for sleep quality test
Valence:
It is obviously improved: being clearly better compared with the state of mind after being easier sleep, the more situations disappearances of night dream before test, feeling)；
Improve: compared with being easy before testing, sleep, the more situations of night dream improve, the state of mind is improved after feel；
Do not improve: the state of mind is variation after fall asleep before relatively testing situation, night dream situation, feel.
3 sleep quality of table and body weights test result
As can be seen from the above table: although tested personnel's weight does not have significant change, sleep quality is improved mostly, in conjunction with table
It follows that as physical function improves, the sleep quality of testee is also improved 2 test results.
Liver-protecting efficacy test two:
(1) it chooses health Wistar healthy adult health white mouse 60 and is only equally divided into 6 groups, wherein one group is blank control group,
Other five groups are mixed into the health liquor in feed in 1~embodiment of feeding embodiment 5, continuous feeding respectively with 30mL/ days dosage
50 days.
(2) the 51st days, by above-mentioned six groups of test small white mouses respectively with 1mL/kg stomach-filling carbon tetrachloride, after a week again with
2mL/kg stomach-filling carbon tetrachloride manufactures liver injury model, during which still presses step (1) grouping feeding feed respectively.
(3) the 65th days, each experimental group white mouse of empty stomach deep anaesthesia took out liver, liver pulp is made and surveys respectively
MDA and GSH content in liver pulp, taking every cell mean is test result, that measures that the results are shown in Table 1
4 liver protective effect test result of table
Remarks: MDA is the end products that lipid peroxide is decomposed, and MDA content can be with indirect reaction body lipid peroxidation
Degree, GSH are a kind of low molecule scavengers, can prevent and treat hemoglobin and other confactors receive oxidative damage, GSH content is weighing apparatus
An important factor for measuring antioxidant ability of organism size.
Lozenge prepared by the present invention has apparent prevention and treatment hepatic injury effect it can be seen from upper table test result.
Finally, it is stated that preferred embodiment above is only used to illustrate the technical scheme of the present invention rather than limits, although logical
It crosses above preferred embodiment the present invention is described in detail, however, those skilled in the art should understand that, can be
Various changes are made to it in form and in details, without departing from claims of the present invention limited range.
Claims (7)
1. a kind of Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor for alleviating physical fatigue, it is characterised in that: be by Notogineng Extract, Huang
Essence extract, cornel extractive and Herba Dendrobii extract after certain compatibility with white spirit mixed to form.
2. a kind of Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor for alleviating physical fatigue according to claim 1, feature exist
In: each extract is prepared as following weight percent: Notogineng Extract 14~30%, Rhizoma Polygonati extract 20~40%, mountain Zhu
Cornel extract 10~43%, Herba Dendrobii extract 10~40%.
3. a kind of preparation method for the Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor for alleviating physical fatigue, characterized by comprising:
(1) Notogineng Extract is made using alcohol extraction process using Radix Notoginseng as raw material；
(2) Rhizoma Polygonati extract is made using extraction process by water using rhizoma polygonati as raw material；
(3) cornel extractive is made using alcohol extraction process using Fructus Corni as raw material；
(4) Herba Dendrobii extract is made using extraction process by water using dendrobium nobile as raw material；
(5) by said extracted object and 50 degree of white spirit mixeds up to the Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor for alleviating physical fatigue.
4. the Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor according to claim 3 for alleviating physical fatigue, it is characterised in that three
The preparation of seven extracts includes the following steps:
(1) Radix Notoginseng powder prepares: will cross 10 meshes after Radix Notoginseng cleaning, dry, smashing；
(2) alcohol extracting three times: being that 85% ethyl alcohol is mixed with the mass ratio of 1:10 by Radix Notoginseng powder and concentration, 90 degree at a temperature of extract 2
Hour, obtain an extracting solution；The Radix Notoginseng powder once extracted will be passed through to pour into 85% ethyl alcohol in the mass ratio of 1:10, at 90 degree
At a temperature of extract 1.5 hours, obtain secondary raffinate；By the Radix Notoginseng powder Jing Guo second extraction to pour into 85% in the mass ratio of 1:10
Ethyl alcohol, 90 degree at a temperature of extract 1.0 hours, obtain extracting solution three times；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: will once extract filtrate, second extraction filtrate and extraction filtrate is concentrated in vacuo respectively three times；
(5) extract mixes: by the extract obtained mixing of step (4) to get Notogineng Extract.
5. the Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor according to claim 3 for alleviating physical fatigue, it is characterised in that yellow
The preparation of essence extract includes the following steps:
(1) rhizoma polygonati prepares: raw sealwort being cleaned up and crushed 10 meshes；
(2) water mentions three times: rhizoma polygonati piece is mixed with distilled water with the mass ratio of 1:10,95 degree at a temperature of extract 1.5 hours,
Obtain an extracting solution；Will by the rhizoma polygonati that once extracts to pour into distilled water in the mass ratio of 1:8,95 degree at a temperature of extract
1.0 hours, obtain secondary raffinate；By the rhizoma polygonati Jing Guo second extraction to pour into distilled water in the mass ratio of 1:6, in 95 degree of temperature
Degree is lower to be extracted 1.0 hours, and extracting solution three times is obtained；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: by it is primary extract filtrate, second extraction filtrate and three times extract filtrate respectively 75 DEG C at a temperature of
It is concentrated in vacuo；
(5) extract mixes: by the extract obtained mixing of step (4) to get Rhizoma Polygonati extract.
6. the Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor according to claim 3 for alleviating physical fatigue, it is characterised in that mountain
The preparation of rutaecarpa extract includes the following steps:
(1) it crushes: Fructus Corni is crushed and sieved with 100 mesh sieve；
(2) alcohol extracting three times: Fructus Corni powder is mixed with 85% ethyl alcohol with the mass ratio of 1:20, at 50 °C ultrasound extraction
30min obtains an extracting solution；The Fructus Corni powder once extracted will be passed through to pour into 85% ethyl alcohol in the mass ratio of 1:10, at 50 DEG C
At a temperature of ultrasound extraction 30min, obtain secondary raffinate；By the Fructus Corni powder Jing Guo second extraction to be poured into the mass ratio of 1:10
85% ethyl alcohol, ultrasound extraction 30min, obtains extracting solution three times at 50 °C；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: by it is primary extract filtrate, second extraction filtrate and three times extract filtrate respectively 75 DEG C at a temperature of
It is concentrated in vacuo；
(5) extract mixes: by the extract obtained mixing of step (4) to get cornel extractive.
7. the Radix Notoginseng rhizoma polygonati Fructus Corni dendrobium nobile health liquor according to claim 3 for alleviating physical fatigue, it is characterised in that stone
The preparation of dry measure used in former times extract includes the following steps:
(1) dendrobium nobile prepares: dendrobium nobile being crushed, 10 meshes are crossed；
(2) water mentions three times: dendrobium nobile piece is mixed with distilled water with the mass ratio of 1:30,90 degree at a temperature of extract 2.0 hours,
Obtain an extracting solution；Will by the dendrobium nobile that once extracts to pour into distilled water in the mass ratio of 1:20,90 degree at a temperature of mention
It takes 1.5 hours, obtains secondary raffinate；By the dendrobium nobile Jing Guo second extraction to pour into distilled water in the mass ratio of 1:15, at 90 degree
At a temperature of extract 1.0 hours, obtain extracting solution three times；
(3) extracting solution filters: by an extracting solution, secondary raffinate and the extracting solution successively mistake in the same filter device three times
Filter respectively obtains primary extraction filtrate, second extraction filtrate and extracts filtrate three times；
(4) extracting solution is concentrated: by it is primary extract filtrate, second extraction filtrate and three times extract filtrate respectively 75 DEG C at a temperature of
It is concentrated in vacuo；
(5) extract mixes: by the extract obtained mixing of step (4) to get Herba Dendrobii extract.
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