CN106418143A - Composition for improving sleep and vision and application thereof - Google Patents

Composition for improving sleep and vision and application thereof Download PDF

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Publication number
CN106418143A
CN106418143A CN201610814774.7A CN201610814774A CN106418143A CN 106418143 A CN106418143 A CN 106418143A CN 201610814774 A CN201610814774 A CN 201610814774A CN 106418143 A CN106418143 A CN 106418143A
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parts
sleep
composition
health care
eyesight
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CN201610814774.7A
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Chinese (zh)
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杨森健
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
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Abstract

The invention provides a composition for improving sleep and vision and an application thereof. The composition is prepared from, by weight, 2000 parts of probiotics enzymes, 3-10 parts of dateplum persimmon, 3-5 parts of Chinese yam, 3-5 parts of hawthorn, 3-5 parts of herba portulacae, 3-5 parts of smoked plum, 3-5 parts of pawpaw, 3-5 parts of ginkgo, 3-5 parts of white hyacinth bean, 3-5 parts of flower of white hyacinth bean, 3-5 parts of longan aril, 0.5-1 part of gamma-aminobutyric, 3-5 parts of huckleberry, 0.5-2 parts of xanthophyll, 3-5 parts of periostracum cicada, 5-7 parts of dilapidated walls ganoderma lucidum spore powder, 5-7 parts of ginseng, 10-25 parts of medlar, 10-25 parts of poria cocos and the like. The composition is rich in various nutritional ingredients necessary to human body, has various medicinal compositions at the same time, can be subjected to all-around nursing to function of human body from six aspects of soothing the nerves, improving acuity of vision, tonifying spleen, helping digestion, relaxing the bowels and nourishing the body, and has very good capacity of improving sleep and vision.

Description

A kind of composition improving the health care of sleep with eyesight and application thereof
Technical field
The present invention relates to field of health care products field, in particular to a kind of composition improving the health care of sleep with eyesight and its Purposes.
Background technology
People in life, has 1/3rd time to spend in sleep, and sitting up within five days to affect the life of people Deposit it is seen that sleeping is one of important physiological requirements of people.Sleep is process necessary to life, is that body restores, integrates and consolidates Gu the important step of memory, it is also healthy indispensable part.According to World Health Organization's investigation, there is 27% people to have and sleep Dormancy problem.
Long-term taking hypnotic has very big side effect, is fed up with such as daytime, energy is not concentrated, slow in reacting, note Recall and go down, in addition, Long-Time Service also can assume dose dependent.And mainly rely on liver to turn as stabilizing this kind of hypnotic Change, kidney is discharged, therefore long-term excessive use, the burden of hepatic and renal function can be increased.
Content of the invention
The first object of the present invention is to provide a kind of composition improving the health care of sleep with eyesight, this composition from calming the nerves, Improving eyesight, invigorating the spleen, help digestion, defaecation and nourish this six aspects, omnibearing conditioning is carried out to function of human body, has well Improve the health care of sleep the ability with eyesight.
The second object of the present invention is to provide a kind of described improving the health care of sleep to improve the health care of sleep in preparation with the composition of eyesight Medicine or health products in application.
The third object of the present invention is to provide a kind of described improving the health care of sleep to improve eyesight with the composition of eyesight in preparation Medicine or health products in application.
In order to realize the above-mentioned purpose of the present invention, spy employs the following technical solutions：
A kind of composition improving the health care of sleep with eyesight, the raw material of composition includes by weight：
2000 parts of probio ferment, dateplum persimmon benevolence 3-10 part, millet 3-5 part, three carob 3-5 parts, mango 3-5 part, chrysanthemum Flower 3-5 part, sour cherry 3-5 part, walnut 3-5 part, banana 3-5 part, cabbage mustard 3-5 part, sole 3-5 part, mealy potato 3-5 Part, almond 3-5 part, oat 3-5 part, Chinese yam 3-5 part, hawthorn 3-5 part, purslane 3-5 part, dark plum 3-5 part, pawpaw 3-5 part, fructus cannabis 3-5 part, bitter orange flower 3-5 part, radix polygonati officinalis 3-5 part, Radix Glycyrrhizae 3-5 part, root of Dahurain angelica 3-5 part, Noni puree 3- 5 parts, gingko 3-5 part, Semen Lablab Album 3-5 part, Flos Semen Lablab Album 3-5 part, arillus longan 3-5 part, GABA 0.5-1 part, Cowberry 3-5 part, lutein 0.5-2 part, cicada slough 3-5 part, ganoderma spove powder 5-7 part, ginseng 5-7 part, matrimony vine 10- 25 parts, Poria cocos 10-25 part, dietary fiber 20-30 part, L-arabinose 10-20 part and pectin 3-5 part.
Compared with prior art, beneficial effects of the present invention are：
(1) jujube kernel and arillus longan are respectively provided with effect of antitoxic heart-soothing and sedative, mutual compatibility, have the effect assisting synergy, enter one The collaborative GABA of step, makes the effect that said composition improves the health care of sleep significantly strengthen.Ginseng and the benefiting action of Poria cocos By force, the effect of said composition relieving restlessness that clears away heart-fire, calming heart and tranquilizing mind can be strengthened.
(2) effect clear liver and improved vision of Semen Lablab Album and Flos Semen Lablab Album is notable, then is aided with this three taste of cowberry, cicada slough and matrimony vine There is the medicinal material of improving eyesight effect, there is the effect of Synergistic.In the collective effect with lutein, this group can be significantly improved The ability improving eyesight of compound.
(3) said composition also has cereal, mango hawthorn of invigorating the spleen effect etc. containing millet, oat etc. and has and helps digestion in addition The gourd, fruit and vegetable of stomach invigorating effect, almond fructus cannabis etc. have medicinal material and Chinese yam root of Dahurain angelica of effect of relaxing bowel etc. and have nourishing The medicinal material of effect, improves the physiological function of human body from multiple angles, adjusts total balance of the body, thus reach improving the health care of sleep and eyesight Effect.
Specific embodiment
Below in conjunction with embodiment, embodiment of the present invention is described in detail, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and be not construed as limiting the scope of the present invention.Unreceipted concrete in embodiment Condition person, the condition according to normal condition or manufacturer's suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, are Can be by the commercially available conventional products bought and obtain.
The present embodiment provides a kind of composition improving the health care of sleep with eyesight, and the raw material of said composition includes by weight：
2000 parts of probio ferment, dateplum persimmon benevolence 3-10 part, millet 3-5 part, three carob 3-5 parts, mango 3-5 part, chrysanthemum Flower 3-5 part, sour cherry 3-5 part, walnut 3-5 part, banana 3-5 part, cabbage mustard 3-5 part, sole 3-5 part, mealy potato 3-5 Part, almond 3-5 part, oat 3-5 part, Chinese yam 3-5 part, hawthorn 3-5 part, purslane 3-5 part, dark plum 3-5 part, pawpaw 3-5 part, fructus cannabis 3-5 part, bitter orange flower 3-5 part, radix polygonati officinalis 3-5 part, Radix Glycyrrhizae 3-5 part, root of Dahurain angelica 3-5 part, Noni puree 3- 5 parts, gingko 3-5 part, Semen Lablab Album 3-5 part, Flos Semen Lablab Album 3-5 part, arillus longan 3-5 part, GABA 0.5-1 part, Cowberry 3-5 part, lutein 0.5-2 part, cicada slough 3-5 part, ganoderma spove powder 5-7 part, ginseng 5-7 part, matrimony vine 10- 25 parts, Poria cocos 10-25 part, dietary fiber 20-30 part, L-arabinose 10-20 part and pectin 3-5 part.
In preferred embodiments of the present invention, by weight, above-mentioned probio ferment is 2000 parts, and dateplum persimmon benevolence is 5-8 Part, millet is 4-5 part, and three carobs are 4-5 part, and mango is 3-4 part, and chrysanthemum is 3-4 part, and sour cherry is 3-4 part, walnut For 4-5 part, banana is 4-5 part, and cabbage mustard is 3-4 part, and sole is 4-5 part, and mealy potato is 3-4 part, and almond is 3-4 part, Oat is 3-4 part, and Chinese yam is 4-5 part, and hawthorn is 4-5 part, and purslane is 4-5 part, and dark plum is 3-4 part, and pawpaw is 3-4 Part, fructus cannabis is 3-4 part, and bitter orange flower is 4-5 part, and radix polygonati officinalis is 4-5 part, and Radix Glycyrrhizae is 4-5 part, and the root of Dahurain angelica is 4-5 part, Nuo Li Pulp is 3-4 part, and gingko is 3-4 part, and Semen Lablab Album is 3-4 part, and Flos Semen Lablab Album is 3-4 part, and arillus longan is 4-5 part, γ- Aminobutyric acid is 0.7-0.9 part, and cowberry is 4-5 part, and lutein is 1-1.5 part, and cicada slough is 4-5 part, wall-broken ganoderma spore Powder is 5-6 part, and ginseng is 5-6 part, and matrimony vine is 15-20 part, and Poria cocos is 15-20 part, and dietary fiber is 23-28 part, L- Arabinose is 13-27 part, and pectin is 4-5 part.
Most preferably, by weight, above-mentioned probio ferment is 2000 parts, and dateplum persimmon benevolence is 7 parts, and millet is 4 parts, triangle Beans are 4 parts, and mango is 3 parts, and chrysanthemum is 3 parts, and sour cherry is 4 parts, and walnut is 5 parts, and banana is 5 parts, and cabbage mustard is 3 parts, and sole is 5 Part, mealy potato is 4 parts, and almond is 3 parts, and oat is 3 parts, and Chinese yam is 5 parts, and hawthorn is 5 parts, and purslane is 4 parts, and dark plum is 3 parts, Pawpaw is 4 parts, and fructus cannabis is 4 parts, and bitter orange flower is 5 parts, and radix polygonati officinalis is 4 parts, and Radix Glycyrrhizae is 4 parts, and the root of Dahurain angelica is 5 parts, and Noni puree is 4 Part, gingko is 3 parts, and Semen Lablab Album is 3 parts, and Flos Semen Lablab Album is 4 parts, and arillus longan is 5 parts, and GABA is 0.8 part, and cowberry is 5 parts, lutein is 1.3 parts, and cicada slough is 4 parts, and ganoderma spove powder is 6 parts, and ginseng is 6 parts, and matrimony vine is 18 parts, and Poria cocos is 18 Part, dietary fiber is 25 parts, and L-arabinose is 20 parts, and pectin is 5 parts.
Calm the nerves aspect：
GABA, is critically important inhibitory neurotransmitter in central nervous system, and it is that one kind naturally occurs Non-protein composition amino acid.GABA can promote the reactivity of brain, brain tonic and intelligence development, promotes sleep, delays cerebral senility Old function, human body inhibitory neurotransmitter can be supplemented.
Jujube kernel, as spina date seed, flat property and sweet taste, there is the effect of antitoxic heart-soothing and sedative, be the middle classical key medicine curing insomnia.Modern times grind Study carefully and show, spina date seed plays the role of to suppress central nervous system stimulant, is favorably improved sleep quality.Arillus longan, taste warm in nature is sweet, There is tonifying heart and spleen, nourishing blood and tranquilization.Jujube kernel and the mutual compatibility of arillus longan, have the effect assisting synergy, further Collaborative GABA, makes the effect that said composition improves the health care of sleep significantly strengthen.
Ginseng, have functions that tonifying Qi promote the production of body fluid, tranquilize the mind and promote the intelligence；Modern pharmacological research shows that ginseng can adjust nerveous system System, and cerebral blood flow (CBF) and brain energy metabolism can be increased.Poria cocos, has functions that clearing damp and promoting diuresis, invigorating the spleen calming heart.Ginseng and Poria cocos Benefiting action strong, the effect of said composition relieving restlessness that clears away heart-fire, calming heart and tranquilizing mind can be strengthened.
Ganoderma spove powder, rich in the trace element having GL-B, ganoderic acid and all kinds of needed by human body, can Improve body blood circulation, there is the neurasthenic effect of alleviation.
Improving eyesight aspect：
Lutein, is a kind of antioxidant of excellent performance, can resist oxygen radical and cause cell and organ in human body Damage, the symptom such as the cardiovascula arteriosclerosis of prevention body aging initiation, coronary heart disease.Above all lutein is that uniquely there may be The carotenoid composition of eyes crystalline, is primary pigments and the antioxidant content of macula retinae, many ophthalmology diseases all with The shortage of lutein has much relations, and lutein plays important protective effect for eyes.
Semen Lablab Album and Flos Semen Lablab Album, have invigorating the spleen for eliminating dampness, inducing diuresis to remove edema, the effect clear liver and improved vision.Cowberry, has raising and regards Power and effect of prevention system vascular hardening.Cicada slough, enters Liver Channel, has dispelling wind and heat from the body, effect of removing nebula.Matrimony vine, has Nourshing kidney moistening lung, effect of nourishing liver and improving eyesight.Chrysanthemum has clearing heat and detoxicating, effect of the flat liver of purging intense heat.
The effect clear liver and improved vision of Semen Lablab Album and Flos Semen Lablab Album is notable, then is aided with this three taste of cowberry, cicada slough and matrimony vine tool There is the medicinal material of improving eyesight effect, there is the effect of Synergistic.In the collective effect with lutein, this combination can be significantly improved The ability improving eyesight of thing.
Invigorating the spleen aspect：
Millet, is one of five cereals, and rich in having abundant vitamin B1 and B12, its nourishing the stomach effect is notable.Three carobs, also known as Chick-pea, is a kind of very precious rare germ plasm resource, and belongs to high nutrition bean, rich in various plants albumen and The composition such as several amino acids, vitamin, crude fibre and calcium, magnesium, iron.Oat, nature and flavor are sweet flat, have beneficial spleen nourishing heart, the work(of arrest sweating Effect.
Millet, three carobs and oat, are the food of often to eat in daily life, can strengthening spleen and nourishing stomach, thus improving Effect with all worries set aside of calming the nerves of said composition.
Help digestion aspect：
Mango, is " king of tropical fruit (tree) ", has reinforcing stomach reg fluid, the inverse effect of fall of quenching the thirst.Containing nutrient and vitamin C, mineral matter etc., in addition to having functions that anti-cancer, also have prevents the dietary function of artery sclerosis and hypertension simultaneously.Banana There is heat-clearing, ease constipation, removing toxic substances, nourishing yin to moisten dryness and promote the production of body fluid to quench thirst.Being rich in cabbage mustard has substantial amounts of carrotene, vitamin C And glucosinolate.Sole has functions that wines used as antirheumatic, promoting blood circulation and removing obstruction in channels.Dark plum, has functions that convergence is promoted the production of body fluid.Pawpaw, tool There is reinforcing spleen to promote digestion.Hawthorn, sweet, slightly warm in nature is sour, has functions that food digesting stomach fortifying, promoting blood circulation and removing blood stasis.Bitter orange flower, has row In gas width, help digestion, effect of relieving the gastric disorder and regulating vital energy.Noni puree is by the Noni fruit after maturation, pulls an oar and obtain after cleaning peeling seed.
By these melon and fruit vegetables of mango, banana, cabbage mustard, sole, dark plum, pawpaw, hawthorn, bitter orange flower and Noni puree The compatibility of dish, enriches the species of nutrient content in said composition, concurrently facilitates food digesting stomach fortifying, improves nutrition in said composition Composition and the absorption of effective component.
Defaecation aspect：
Almond, has functions that sending down abnormally ascending is relieving cough and asthma, relaxes bowel.Fructus cannabis, has the effect of relax bowel.Mealy potato Have in adjusting with stomach, invigorating spleen to remove dampness, wide intestines defaecation, hypoglycemic the effect of.
Almond, fructus cannabis and mealy potato are respectively provided with the effect relaxing bowel, and conditioning engine body can balance, contribute to seeking in a large number Form the discarded object after metabolism in lease making body, toxin etc. to discharge in time, thus avoid leading to because supplementing a large number of nutrients Body heat is dried constipation.
Nourishing aspect：
Chinese yam, have nourishing strong, aid digestion, hold back the effect of abnormal sweating, antidiarrheal.Purslane is medicine food dual purpose plant, has Clearing heat and promoting diuresis, removing toxicity for detumescence, anti-inflammatory, quench the thirst, effect of diuresis.Radix polygonati officinalis, has functions that nourishing yin to moisten dryness, promotes the production of body fluid to quench thirst.Radix Glycyrrhizae There is invigorating middle warmer and replenishing QI, coordinating the drug actions of a prescription.The root of Dahurain angelica, has and expels pathogenic wind from the body surface, effect of eliminating cold to stop pain.Gingko, has reduction blood Clearing gallbladder sterol, effect of coronary artery dilator.
Chinese yam, purslane, radix polygonati officinalis, the root of Dahurain angelica, gingko and Radix Glycyrrhizae, this Six-element medicinal material can strengthen the help work(of said composition Effect, makes the heat-clearing of said composition wind action of dispelling strengthen, thus preventing benefiting action from crossing the side effect contained and lead to simultaneously again.
Probio ferment powder, can effectively improve intestinal health, balance flora, coordinating intestines and stomach, strengthen immunity of organism Function.L-arabinose and pectin are sweetener, improve the mouthfeel of said composition.
In preferred embodiments of the present invention, above-mentioned raw materials are the powder that granularity is 100-300 mesh, preferably 200 mesh Powder.The raw material good mixing effect of this granularity, and granularity is little, nutrient content and the easy dissolution of active principle, thus easily quilt Absorption of human body.
In preferred embodiments of the present invention, above-mentioned dietary fiber includes fruit-vegetable fibre and/or common oats fibre.Further , by weight, above-mentioned fruit-vegetable fibre is 10-15 part., common oats fibre is 10-15 part.Highly preferred, above-mentioned fruits and vegetables Fiber is 12 parts, and common oats fibre is 12 parts.Fruit-vegetable fibre is with commonly used water fruits and vegetables in daily life as Raw material processing The fiber element obtaining, has clearing heat and promoting diuresis, stomach invigorating is refreshed oneself, relax bowel, clearing heat and detoxicating water level effect.Common oats fibre be with Herba bromi japonici dietary fiber obtains for Raw material processing, and the ratio of its soluble dietary fiber increases it is easy to digest.
In preferred embodiments of the present invention, above-mentioned ganoderma spove powder is using high pressure purified air cutting mill Reishi sporule is pulverized broken wall and is obtained by technology.This is because Reishi sporule has one layer of extremely difficult chitin quality structure being digested by human body hydrochloric acid in gastric juice Become outer wall, not the conidia powder human body of broken wall cannot digest and assimilate, only open this layer of outer wall, the active ingredient being wrapped tightly by outer wall Absorption could be farthest immediately used by the body, so that effect of said composition strengthens.
In preferred embodiments of the present invention, above-mentioned dateplum persimmon benevolence obtains for jujube kernel processes through stir-fry charcoal method.Jujube kernel fry charcoal it Its sour and astringent property of medicine has been alleviated afterwards, reduces side effect, strengthens effect of its antitoxic heart-soothing and sedative.
Present embodiment also provides and this improves the health care of sleep the medicine improving the health care of sleep in preparation with the composition of eyesight or guarantor Application in strong product.As the above analysis, said composition has functions that to calm the nerves well nourishing heart, can be applied to preparation and change The medicine of kind sleep or health products.
Present embodiment also provides this medicine or the health care improving the health care of sleep and improving eyesight with the composition of eyesight in preparation Application in product.As the above analysis, said composition has functions that to clear liver and improve vision well, can be applied to preparation and improve The medicine of eyesight or health products.
This composition can be processed into multiple formulations according to conventional methods, for example pill, tablet, capsule, pulvis, Granula, oral liquid etc..A kind of preparation method of pulvis is provided in the present embodiment, will raw material powder respectively in above-mentioned formula After being broken to 100-300 mesh, mix and obtain final product.
Embodiment 1
The present embodiment provides a kind of composition improving the health care of sleep with eyesight, and the raw material of said composition includes by weight：
2000 parts of probio ferment, 3 parts of dateplum persimmon benevolence, 5 parts of millet, 5 parts of three carob, 3 parts of mango, 3 parts of chrysanthemum, sour cherry 5 Part, 5 parts of walnut, 5 parts of banana, 3 parts of cabbage mustard, 5 parts of sole, 5 parts of mealy potato, 3 parts of almond, 5 parts of oat, 5 parts of Chinese yam, 5 parts of hawthorn, 3 parts of purslane, 5 parts of dark plum, 3 parts of pawpaw, 5 parts of fructus cannabis, 3 parts of bitter orange flower, 5 parts of radix polygonati officinalis, 5 parts of Radix Glycyrrhizae, 3 parts of the root of Dahurain angelica, Noni fruit 3 parts of slurry, 5 parts of gingko, 5 parts of Semen Lablab Album, 3 parts of Flos Semen Lablab Album, 5 parts of arillus longan, 1 part of GABA, 3 parts of cowberry, lutein 2 Part, 5 parts of cicada slough, 7 parts of ganoderma spove powder, 5 parts of ginseng, 10 parts of matrimony vine, 10 parts of Poria cocos, 20 parts of dietary fiber, L- are Arabic Sugared 20 parts and 3 parts of pectin.
The method that said composition is prepared into pulvis is：Above-mentioned raw materials are crushed to after 100 mesh, mix and obtain final product.
Embodiment 2
The present embodiment provides a kind of composition improving the health care of sleep with eyesight, and the raw material of said composition includes by weight：
2000 parts of probio ferment, 5 parts of dateplum persimmon benevolence, 5 parts of millet, 4 parts of three carob, 3 parts of mango, 4 parts of chrysanthemum, sour cherry 4 Part, 5 parts of walnut, 5 parts of banana, 3 parts of cabbage mustard, 5 parts of sole, 4 parts of mealy potato, 3 parts of almond, 3 parts of oat, 5 parts of Chinese yam, 4 parts of hawthorn, 5 parts of purslane, 4 parts of dark plum, 3 parts of pawpaw, 4 parts of fructus cannabis, 4 parts of bitter orange flower, 4 parts of radix polygonati officinalis, 5 parts of Radix Glycyrrhizae, 5 parts of the root of Dahurain angelica, Noni fruit 4 parts of slurry, 3 parts of gingko, 4 parts of Semen Lablab Album, 3 parts of Flos Semen Lablab Album, 4 parts of arillus longan, 0.9 part of GABA, 4 parts of cowberry, leaf are yellow 1 part of element, 5 parts of cicada slough, 5 parts of ganoderma spove powder, 6 parts of ginseng, 20 parts of matrimony vine, 20 parts of Poria cocos, 23 parts of dietary fiber, L- Ah Draw uncle sugared 13 parts and 5 parts of pectin.
The method that said composition is prepared into pulvis is：Above-mentioned raw materials are crushed to after 300 mesh, mix and obtain final product.
Embodiment 3
The present embodiment provides a kind of composition improving the health care of sleep with eyesight, and the raw material of said composition includes by weight：
2000 parts of probio ferment, 7 parts of dateplum persimmon benevolence, 4 parts of millet, 4 parts of three carob, 3 parts of mango, 3 parts of chrysanthemum, sour cherry 4 Part, 5 parts of walnut, 5 parts of banana, 3 parts of cabbage mustard, 5 parts of sole, 4 parts of mealy potato, 3 parts of almond, 3 parts of oat, 5 parts of Chinese yam, 5 parts of hawthorn, 4 parts of purslane, 3 parts of dark plum, 4 parts of pawpaw, 4 parts of fructus cannabis, 5 parts of bitter orange flower, 4 parts of radix polygonati officinalis, 4 parts of Radix Glycyrrhizae, 5 parts of the root of Dahurain angelica, Noni fruit 4 parts of slurry, 3 parts of gingko, 3 parts of Semen Lablab Album, 4 parts of Flos Semen Lablab Album, 5 parts of arillus longan, 0.8 part of GABA, 5 parts of cowberry, leaf are yellow 1.3 parts of element, 4 parts of cicada slough, 6 parts of ganoderma spove powder, 6 parts of ginseng, 18 parts of matrimony vine, 18 parts of Poria cocos, 25 parts of dietary fiber, L- 20 parts of arabinose and 5 parts of pectin.
The method that said composition is prepared into pulvis is：Above-mentioned raw materials are crushed to after 200 mesh, mix and obtain final product.
Embodiment 4
The present embodiment provides a kind of composition improving the health care of sleep with eyesight, the preparation method of said composition and embodiment 3 one Cause, difference is that the raw material of said composition includes by weight：
2000 parts of probio ferment, 8 parts of dateplum persimmon benevolence, 4 parts of millet, 5 parts of three carob, 4 parts of mango, 3 parts of chrysanthemum, sour cherry 3 Part, 4 parts of walnut, 4 parts of banana, 4 parts of cabbage mustard, 4 parts of sole, 3 parts of mealy potato, 4 parts of almond, 4 parts of oat, 4 parts of Chinese yam, 5 parts of hawthorn, 4 parts of purslane, 3 parts of dark plum, 4 parts of pawpaw, 3 parts of fructus cannabis, 5 parts of bitter orange flower, 5 parts of radix polygonati officinalis, 4 parts of Radix Glycyrrhizae, 4 parts of the root of Dahurain angelica, Noni fruit 3 parts of slurry, 4 parts of gingko, 3 parts of Semen Lablab Album, 4 parts of Flos Semen Lablab Album, 5 parts of arillus longan, 0.7 part of GABA, 5 parts of cowberry, leaf are yellow 1.5 parts of element, 4 parts of cicada slough, 6 parts of ganoderma spove powder, 5 parts of ginseng, 15 parts of matrimony vine, 15 parts of Poria cocos, 28 parts of dietary fiber, L- 27 parts of arabinose and 4 parts of pectin.
Embodiment 5
The present embodiment provides a kind of composition improving the health care of sleep with eyesight, the preparation method of said composition and embodiment 3 one Cause, difference is that the raw material of said composition includes by weight：
2000 parts of probio ferment, 10 parts of dateplum persimmon benevolence, 3 parts of millet, 3 parts of three carob, 5 parts of mango, 5 parts of chrysanthemum, sour cherry 3 Part, 3 parts of walnut, 3 parts of banana, 5 parts of cabbage mustard, 3 parts of sole, 3 parts of mealy potato, 5 parts of almond, 3 parts of oat, 3 parts of Chinese yam, 3 parts of hawthorn, 5 parts of purslane, 3 parts of dark plum, 5 parts of pawpaw, 3 parts of fructus cannabis, 5 parts of bitter orange flower, 3 parts of radix polygonati officinalis, 3 parts of Radix Glycyrrhizae, 5 parts of the root of Dahurain angelica, Noni fruit 5 parts of slurry, 3 parts of gingko, 3 parts of Semen Lablab Album, 5 parts of Flos Semen Lablab Album, 3 parts of arillus longan, 0.5 part of GABA, 5 parts of cowberry, leaf are yellow 0.5 part of element, 5 parts of cicada slough, 5 parts of ganoderma spove powder, 7 parts of ginseng, 25 parts of matrimony vine, 25 parts of Poria cocos, 30 parts of dietary fiber, L- 10 parts of arabinose and 5 parts of pectin.
Embodiment 6
The present embodiment provides a kind of composition improving the health care of sleep with eyesight, the preparation method of said composition and embodiment 3 one Cause, difference is that the raw material of said composition includes by weight：
2000 parts of probio ferment, 10 parts of dateplum persimmon benevolence, 3 parts of millet, 3 parts of three carob, 5 parts of mango, 5 parts of chrysanthemum, sour cherry 3 Part, 3 parts of walnut, 3 parts of banana, 5 parts of cabbage mustard, 3 parts of sole, 3 parts of mealy potato, 5 parts of almond, 3 parts of oat, 3 parts of Chinese yam, 3 parts of hawthorn, 5 parts of purslane, 3 parts of dark plum, 5 parts of pawpaw, 3 parts of fructus cannabis, 5 parts of bitter orange flower, 3 parts of radix polygonati officinalis, 3 parts of Radix Glycyrrhizae, 5 parts of the root of Dahurain angelica, Noni fruit 5 parts of slurry, 3 parts of gingko, 3 parts of Semen Lablab Album, 5 parts of Flos Semen Lablab Album, 3 parts of arillus longan, 0.5 part of GABA, 5 parts of cowberry, leaf are yellow 0.5 part of element, 5 parts of cicada slough, 5 parts of ganoderma spove powder, 7 parts of ginseng, 25 parts of matrimony vine, 25 parts of Poria cocos, fruit-vegetable fibre are 10 parts, swallow Wheat fiber is 15 parts, 10 parts of L-arabinose and 5 parts of pectin.
Embodiment 7
The present embodiment provides a kind of medicine improving the health care of sleep with eyesight, and this medicine is pulvis, its preparation method and embodiment 3 Unanimously, difference is that the raw material of this medicine includes by weight：
2000 parts of probio ferment, 10 parts of dateplum persimmon benevolence, 3 parts of millet, 3 parts of three carob, 5 parts of mango, 5 parts of chrysanthemum, sour cherry 3 Part, 3 parts of walnut, 3 parts of banana, 5 parts of cabbage mustard, 3 parts of sole, 3 parts of mealy potato, 5 parts of almond, 3 parts of oat, 3 parts of Chinese yam, 3 parts of hawthorn, 5 parts of purslane, 3 parts of dark plum, 5 parts of pawpaw, 3 parts of fructus cannabis, 5 parts of bitter orange flower, 3 parts of radix polygonati officinalis, 3 parts of Radix Glycyrrhizae, 5 parts of the root of Dahurain angelica, Noni fruit 5 parts of slurry, 3 parts of gingko, 3 parts of Semen Lablab Album, 5 parts of Flos Semen Lablab Album, 3 parts of arillus longan, 0.5 part of GABA, 5 parts of cowberry, leaf are yellow 0.5 part of element, 5 parts of cicada slough, 5 parts of ganoderma spove powder, 7 parts of ginseng, 25 parts of matrimony vine, 25 parts of Poria cocos, fruit-vegetable fibre are 15 parts, swallow Wheat fiber is 10 parts, 10 parts of L-arabinose and 5 parts of pectin.
Embodiment 8
The present embodiment provides a kind of health products improving the health care of sleep with eyesight, and this health products is pulvis, its preparation method and reality Apply example 3 unanimously, difference is that the raw material of this health products includes by weight：
2000 parts of probio ferment, 10 parts of dateplum persimmon benevolence, 3 parts of millet, 3 parts of three carob, 5 parts of mango, 5 parts of chrysanthemum, sour cherry 3 Part, 3 parts of walnut, 3 parts of banana, 5 parts of cabbage mustard, 3 parts of sole, 3 parts of mealy potato, 5 parts of almond, 3 parts of oat, 3 parts of Chinese yam, 3 parts of hawthorn, 5 parts of purslane, 3 parts of dark plum, 5 parts of pawpaw, 3 parts of fructus cannabis, 5 parts of bitter orange flower, 3 parts of radix polygonati officinalis, 3 parts of Radix Glycyrrhizae, 5 parts of the root of Dahurain angelica, Noni fruit 5 parts of slurry, 3 parts of gingko, 3 parts of Semen Lablab Album, 5 parts of Flos Semen Lablab Album, 3 parts of arillus longan, 0.5 part of GABA, 5 parts of cowberry, leaf are yellow 0.5 part of element, 5 parts of cicada slough, 5 parts of ganoderma spove powder, 7 parts of ginseng, 25 parts of matrimony vine, 25 parts of Poria cocos, fruit-vegetable fibre are 12 parts, swallow Wheat fiber is 12 parts, 10 parts of L-arabinose and 5 parts of pectin.
Experimental example 1
With reference to zoopery, composition provided in an embodiment of the present invention is commented in the effect improving the health care of sleep aspect Valency.
(1) experimental animal：
Male SD rat, at 3 monthly ages, body weight 180-220g/ only, 60, is provided by University Of Ji'nan's experimental animal center totally, Raise in animal testing center.
(2) packet and processing method：
Rat is randomly divided into 4 groups, every group 15.
Setting control group and experimental group, experimental group includes basic, normal, high three dosage groups (every group 10).Experimental group is applied The pulvis of embodiment 3 preparation, its application process is：Pulvis prepared by embodiment 3 is dissolved in vegetable oil, sample according to《Health products Food Inspection and assessment technique specification》The regulation of (version in 2003) is configured to corresponding concentration, respectively with 0.1g/kg BW, 0.2g/kg BW, the amount of 0.4g/kg BW carry out gavage process to the rat of three dosage groups basic, normal, high in experimental group.Comparison The vegetable oil of group gavage equal solvent amount.Every group of daily gavage once, continuous gavage 45 days.
In each group mouse 15min after last gavage sample, to each group animal lumbar injection yellow Jackets 70mg/kg BW, injection volume is 0.1mL/10gBW.With righting reflex loss as index, when can observation sample extend yellow Jackets sleep Between.
Statistics each group rat the length of one's sleep, and calculate low dose group, middle dose group and high dose group the prolongation time and Rate elongation, result is recorded in table 1.
Wherein extend the time be：Low dose group, the middle dose group and high dose group difference with control group respectively, difference is just Value expression extends the length of one's sleep, and corresponding numerical value is the prolongation time.
Rate elongation is the ratio of the length of one's sleep extending time and control group of low dose group, middle dose group and high dose group Value, then it is multiplied by 100%.
The result of the test of other embodiment is similar to the result of embodiment 3, therefore does not list one by one.
Table 1. given the test agent is to the impact extending the yellow Jackets length of one's sleep
As shown in Table 1：
After successive administration 45 days, compared to control group, in low dose group, middle dose group and high dose group, apply this Bright middle composition can be obviously prolonged the animal sleep time of yellow Jackets effect.Specifically, the length of one's sleep of low dose group Extend 26.09 ± 6.24min, rate elongation is 49.74% ± 3.49；The length of one's sleep of middle dose group extends 29.7 ± 7.41min, rate elongation is 56.63% ± 4.24；The length of one's sleep of high dose group extends 31.11 ± 9.72min, and rate elongation is 59.31% ± 2.67.It is indicated above that said composition can extend the animal sleep time, improve the sleep state of animal, and present Dose dependent.
At present, smoothly carried out in Jinan hospital using the clinical testing that this compound to treat insomniac, and From the point of view of the result of study of early stage, this composition is fine to the drug effect of insomniac, can shorten the time for falling asleep of patient, carry The sleep quality of high patient.
Experimental example 2
Case selection：
Choose the age 15-50 year, long-term be subjects with the fatigable crowd of eye vision, choose 100 and faced Bed test, is randomly divided into two groups, respectively experimental group and control group, every group 50.The eye of experimental group and comparison group membership is tired There was no significant difference for labor sense incidence.
Therapeutic scheme：
Experiment group membership takes the pulvis of the embodiment of the present invention 3 preparation, each 1g, twice daily, continuously takes 1 month. Control group takes the placebo with the pulvis color identical starch making of the present invention, each 1g, and twice daily, the course for the treatment of is 1 Month.
The experimental result of other embodiment is similar to Example 3.
Treatment results：
Subjective sensation evaluation is carried out using questioning, evaluation index includes diet, sleep, mental status and visual fatigue Sense.
After experimental group takes the powder one month of embodiments of the invention 3, the visual fatigue sense having 41 people is substantially changed Kind, it is in particular in that the ophthalmodynia before medication, eye be swollen, photophobia, the dimness of vision and the dry and astringent symptom of eye disappear.6 are had in experimental group People's eye can suddenly feel that eye is swollen, secret anguish, photophobia, the symptom such as dry and astringent, wherein suddenly feel as 1-2 time/2 days.Residue 3 people of experimental group goes out The frequency of existing above-mentioned visual fatigue symptom is slightly many, specially 1-3 times/day.And test group membership and there is no obvious eye strain sense Change.Additionally, there being the eyesight of 32 people to increase before relatively testing in experimental group, increase rate is 0.1-0.2.
Thus illustrate, the composition that the present invention provides effect in terms of improving visual fatigue, raising eyesight is notable, can be by it Improve in medicine or the health products of eyesight for preparation.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that without departing substantially from the present invention's Many other changes can be made in the case of spirit and scope and change.It is, therefore, intended that in the following claims Including all such changes and modifications belonging in the scope of the invention.

Claims (10)

1. a kind of composition improving the health care of sleep with eyesight is it is characterised in that the raw material of described composition includes by weight：
2000 parts of probio ferment, dateplum persimmon benevolence 3-10 part, millet 3-5 part, three carob 3-5 parts, mango 3-5 part, chrysanthemum 3- 5 parts, sour cherry 3-5 part, walnut 3-5 part, banana 3-5 part, cabbage mustard 3-5 part, sole 3-5 part, mealy potato 3-5 part, apricot Benevolence 3-5 part, oat 3-5 part, Chinese yam 3-5 part, hawthorn 3-5 part, purslane 3-5 part, dark plum 3-5 part, pawpaw 3-5 part, Fructus cannabis 3-5 part, bitter orange flower 3-5 part, radix polygonati officinalis 3-5 part, Radix Glycyrrhizae 3-5 part, root of Dahurain angelica 3-5 part, Noni puree 3-5 part, white Fruit 3-5 part, Semen Lablab Album 3-5 part, Flos Semen Lablab Album 3-5 part, arillus longan 3-5 part, GABA 0.5-1 part, cowberry 3-5 part, lutein 0.5-2 part, cicada slough 3-5 part, ganoderma spove powder 5-7 part, ginseng 5-7 part, matrimony vine 10-25 Part, Poria cocos 10-25 part, dietary fiber 20-30 part, L-arabinose 10-20 part and pectin 3-5 part.
2. the composition improving the health care of sleep with eyesight according to claim 1 it is characterised in that by weight, described benefit Raw bacterium ferment is 2000 parts, and described dateplum persimmon benevolence is 5-8 part, and described millet is 4-5 part, and described three carobs are 4-5 part, described Mango is 3-4 part, and described chrysanthemum is 3-4 part, and described sour cherry is 3-4 part, and described walnut is 4-5 part, and described banana is 4-5 part, described cabbage mustard is 3-4 part, and described sole is 4-5 part, and described mealy potato is 3-4 part, and described almond is 3-4 part, Described oat is 3-4 part, and described Chinese yam is 4-5 part, and described hawthorn is 4-5 part, and described purslane is 4-5 part, described crow Plum is 3-4 part, and described pawpaw is 3-4 part, and described fructus cannabis is 3-4 part, and described bitter orange flower is 4-5 part, and described radix polygonati officinalis is 4-5 part, described Radix Glycyrrhizae is 4-5 part, and the described root of Dahurain angelica is 4-5 part, and described Noni puree is 3-4 part, and described gingko is 3-4 Part, described Semen Lablab Album is 3-4 part, and described Flos Semen Lablab Album is 3-4 part, and described arillus longan is 4-5 part, described gamma-amino fourth Acid is 0.7-0.9 part, and described cowberry is 4-5 part, and described lutein is 1-1.5 part, and described cicada slough is 4-5 part, described broken Wall lucidum spore powder is 5-6 part, and described ginseng is 5-6 part, and described matrimony vine is 15-20 part, and described Poria cocos is 15-20 part, Described dietary fiber is 23-28 part, and described L-arabinose is 13-27 part, and described pectin is 4-5 part.
3. the composition improving the health care of sleep with eyesight according to claim 1 it is characterised in that by weight, described benefit Raw bacterium ferment is 2000 parts, and described dateplum persimmon benevolence is 7 parts, and described millet is 4 parts, and described three carobs are 4 parts, and described mango is 3 parts, Described chrysanthemum is 3 parts, and described sour cherry is 4 parts, and described walnut is 5 parts, and described banana is 5 parts, and described cabbage mustard is 3 parts, described Sole is 5 parts, and described mealy potato is 4 parts, and described almond is 3 parts, and described oat is 3 parts, and described Chinese yam is 5 parts, described hawthorn For 5 parts, described purslane is 4 parts, and described dark plum is 3 parts, and described pawpaw is 4 parts, and described fructus cannabis is 4 parts, described bitter orange flower For 5 parts, described radix polygonati officinalis is 4 parts, and described Radix Glycyrrhizae is 4 parts, and the described root of Dahurain angelica is 5 parts, and described Noni puree is 4 parts, and described gingko is 3 Part, described Semen Lablab Album is 3 parts, and described Flos Semen Lablab Album is 4 parts, and described arillus longan is 5 parts, and described GABA is 0.8 part, Described cowberry is 5 parts, and described lutein is 1.3 parts, and described cicada slough is 4 parts, and described ganoderma spove powder is 6 parts, described people Join as 6 parts, described matrimony vine is 18 parts, described Poria cocos is 18 parts, described dietary fiber is 25 parts, described L-arabinose is 20 Part, and described pectin be 5 parts.
4. the composition improving the health care of sleep with eyesight according to claim 1 is it is characterised in that described raw material is granularity is The powder of 100-300 mesh.
5. the composition improving the health care of sleep with eyesight according to claim 1 is it is characterised in that described dietary fiber includes fruit Vegetable fiber and/or common oats fibre.
6. the composition improving the health care of sleep with eyesight according to claim 5 it is characterised in that by weight, described fruit Vegetable fiber is 10-15 part, and described common oats fibre is 10-15 part.
7. the composition improving the health care of sleep with eyesight according to claim 1 is it is characterised in that described ganoderma spove powder It is using high pressure purified air cutting mill technology, Reishi sporule pulverizing broken wall to be obtained.
8. the composition improving the health care of sleep with eyesight according to claim 1 is it is characterised in that described dateplum persimmon benevolence is jujube kernel warp Cross stir-fry charcoal method to process and obtain.
9. any one of claim 1-8 improve the health care of sleep the medicine improving the health care of sleep in preparation with the composition of eyesight or Application in person's health products.
10. any one of claim 1-8 improve the health care of sleep with the composition of eyesight preparation improve eyesight medicine or Application in health products.
CN201610814774.7A 2016-09-09 2016-09-09 Composition for improving sleep and vision and application thereof Pending CN106418143A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107596062A (en) * 2017-09-30 2018-01-19 美可高特羊乳有限公司 It is a kind of that there is sheep breast composition for improving sleep effect and preparation method thereof
CN108042652A (en) * 2018-02-11 2018-05-18 成都图径生物科技有限公司 Composition for relieving asthenopia containing matrimony vine, chrysanthemum and γ-aminobutyric acid
CN110419739A (en) * 2019-09-11 2019-11-08 纯真植物营养素研究院(西安)有限公司 For improving sleep quality, the composition for supplementing brain nutrition and its preparation method and application

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102578577A (en) * 2012-02-27 2012-07-18 苏州爱斯欧蒂生物科技有限公司 Sleep-benefiting brain-benefiting eyesight-improving health care product

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102578577A (en) * 2012-02-27 2012-07-18 苏州爱斯欧蒂生物科技有限公司 Sleep-benefiting brain-benefiting eyesight-improving health care product

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107596062A (en) * 2017-09-30 2018-01-19 美可高特羊乳有限公司 It is a kind of that there is sheep breast composition for improving sleep effect and preparation method thereof
CN108042652A (en) * 2018-02-11 2018-05-18 成都图径生物科技有限公司 Composition for relieving asthenopia containing matrimony vine, chrysanthemum and γ-aminobutyric acid
CN110419739A (en) * 2019-09-11 2019-11-08 纯真植物营养素研究院(西安)有限公司 For improving sleep quality, the composition for supplementing brain nutrition and its preparation method and application

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