CN109180577A - 一种阿立哌唑的制备方法 - Google Patents
一种阿立哌唑的制备方法 Download PDFInfo
- Publication number
- CN109180577A CN109180577A CN201811194211.8A CN201811194211A CN109180577A CN 109180577 A CN109180577 A CN 109180577A CN 201811194211 A CN201811194211 A CN 201811194211A CN 109180577 A CN109180577 A CN 109180577A
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- CN
- China
- Prior art keywords
- preparation
- aripiprazole
- dichloro
- catalyst
- reaction
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201811194211.8A CN109180577B (zh) | 2018-10-15 | 2018-10-15 | 一种阿立哌唑的制备方法 |
Applications Claiming Priority (1)
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CN201811194211.8A CN109180577B (zh) | 2018-10-15 | 2018-10-15 | 一种阿立哌唑的制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN109180577A true CN109180577A (zh) | 2019-01-11 |
CN109180577B CN109180577B (zh) | 2021-11-16 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201811194211.8A Active CN109180577B (zh) | 2018-10-15 | 2018-10-15 | 一种阿立哌唑的制备方法 |
Country Status (1)
Country | Link |
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CN (1) | CN109180577B (zh) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4234585A (en) * | 1978-06-23 | 1980-11-18 | Boehringer Mannheim Gmbh | 1,2-Dihydroquinoline-2-one derivatives |
CN1042537A (zh) * | 1988-10-31 | 1990-05-30 | 大制药株式会社 | 喹诺酮衍生物 |
CN1634889A (zh) * | 2003-12-25 | 2005-07-06 | 成都康弘科技实业(集团)有限公司 | 阿立哌唑的制备方法和中间体 |
-
2018
- 2018-10-15 CN CN201811194211.8A patent/CN109180577B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4234585A (en) * | 1978-06-23 | 1980-11-18 | Boehringer Mannheim Gmbh | 1,2-Dihydroquinoline-2-one derivatives |
CN1042537A (zh) * | 1988-10-31 | 1990-05-30 | 大制药株式会社 | 喹诺酮衍生物 |
CN1634889A (zh) * | 2003-12-25 | 2005-07-06 | 成都康弘科技实业(集团)有限公司 | 阿立哌唑的制备方法和中间体 |
Non-Patent Citations (2)
Title |
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SHAUGHNESSY, KEVIN H等: "Tri-tert-butylphosphine", 《E-EROS ENCYCLOPEDIA OF REAGENTS FOR ORGANIC SYNTHESIS》 * |
黄子杰等: "阿立哌唑的制备", 《精细化工中间体》 * |
Also Published As
Publication number | Publication date |
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CN109180577B (zh) | 2021-11-16 |
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Legal Events
Date | Code | Title | Description |
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20210926 Address after: 264205 268 Tianrun Road, Wendeng economic and Technological Development Zone, Weihai, Shandong Applicant after: Dijia Pharmaceutical Group Co.,Ltd. Address before: 264205 Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Applicant before: Dijia Pharmaceutical Group Co.,Ltd. Applicant before: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Effective date of registration: 20210926 Address after: 264205 Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Applicant after: Dijia Pharmaceutical Group Co.,Ltd. Applicant after: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Address before: 266440 No.268, Tianrun Road, Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Applicant before: WEIHAI DISU PHARMACEUTICAL Co.,Ltd. Applicant before: DISHA PHARMACEUTICAL GROUP Co.,Ltd. |
|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CP03 | Change of name, title or address | ||
CP03 | Change of name, title or address |
Address after: No. 268, Tianrun Road, Wendeng Economic and Technological Development Zone, Weihai City, Shandong Province, 264200 Patentee after: Dijia Pharmaceutical Group Co.,Ltd. Address before: 264205 268 Tianrun Road, Wendeng economic and Technological Development Zone, Weihai, Shandong Patentee before: Dijia Pharmaceutical Group Co.,Ltd. |