CN109174407A - Ultramicro-powder cryogrinding technology - Google Patents
Ultramicro-powder cryogrinding technology Download PDFInfo
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- CN109174407A CN109174407A CN201811004692.1A CN201811004692A CN109174407A CN 109174407 A CN109174407 A CN 109174407A CN 201811004692 A CN201811004692 A CN 201811004692A CN 109174407 A CN109174407 A CN 109174407A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C21/00—Disintegrating plant with or without drying of the material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/10—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
- B08B3/12—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration by sonic or ultrasonic vibrations
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
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Abstract
The present invention relates to a kind of Ultramicro-powder cryogrinding technologies, comprising steps of Radix Notoginseng after drying is crushed using micronizer, obtain superfine notoginseng powder；Wherein, the temperature of crushing is not higher than 0 DEG C；In superfine notoginseng powder, the partial size for the particle that quality accounting is 98% or more is less than 800 mesh；The preparation method of Radix Notoginseng using medical grade ion cleaning water ultrasonic activation comprising steps of twice using conventional drinking water ultrasonic activation cleaning by fresh Roots of Panax Notoginseng, then cleaned twice, re-dry, Radix Notoginseng after being dried after drying.Ultramicro-powder cryogrinding technology provided by the invention, by being crushed under cryogenic, destruction of the fever to pseudo-ginseng activity ingredient and mouthfeel can be operated to avoid machine at high speeds, Radix Notoginseng natural taste and nutritive value are maintained to the maximum extent, and preparation process does not add any auxiliary material and preservative, pure green production, the superfine notoginseng powder being prepared are highly purified.
Description
Technical field
The present invention relates to Chinese medicine processing technique fields, and in particular to a kind of Ultramicro-powder cryogrinding technology.
Background technique
Radix Notoginseng also known as invaluable, is China's tradition rare traditional Chinese medicine, and Chinese medicine Radix Notoginseng is mainly using its root as medicinal
Part.The Radix Notoginseng place of production is Yunnan mountain of papers, sweet in flavor, slight bitter, warm-natured, returns liver and kidney channel, containing saponin(e, polysaccharide, flavones, carbene alcohol,
The effective components such as amino acid, fatty acid and cyclic peptide, with dissipating stasis and stanching bleeding, swelling and pain relieving, antitumor, antiatherosclerosis
Equal pharmacological activity effect is immunized with enhancing.
A variety of Radix Notoginseng micro powder products and corresponding preparation process exists in the prior art, it is more micro- than disclosing Radix Notoginseng if any patent
The processing method of powder, comprising the following steps: addition soybean lecithin；Raw material crushes, and Radix Notoginseng coarse powder is poured into grinder and is ground,
Milling time should be 10 minutes；Ethyl alcohol impregnates；Handle lavender leaf；Lavender juice is added into Radix Notoginseng micro mist for mixed liquid dipping
And pear juice, soaking time should be 10 minutes, panax mixed liquid are added in high pressure homogenizer, temperature should be 50 DEG C, and pressure is answered
For 25MPa；Make Radix Notoginseng micro mist.However, the process employs other a large amount of auxiliary materials, such as lavender and pears, it destroys
The natural taste of Radix Notoginseng and nutritive value.For another example there is patent to disclose a kind of method of micronization of Radix Notoginseng, specifically includes and clean
Process washes process, dry sterilization process, pulverizing process, sieving process and mixed processes processed；However, this method is on the opportunity of crushing
Device runs at high speed fever, some unstable active constituents in Radix Notoginseng is highly vulnerable to breakage, to influence the medical value of Radix Notoginseng.Cause
This, it is also necessary to develop novel Radix Notoginseng powder preparation technique.
Summary of the invention
For the defects in the prior art, it is an object of that present invention to provide a kind of Ultramicro-powder cryogrinding technology, by
It is crushed under cryogenic conditions, destruction of the fever to pseudo-ginseng activity ingredient and mouthfeel can be operated to avoid machine at high speeds, to the maximum extent
The natural taste of Radix Notoginseng and nutritional ingredient being maintained, and preparation process does not add any auxiliary material and preservative, pure green produces,
The superfine notoginseng powder being prepared is highly purified.
To achieve the above object, technical solution provided by the invention are as follows:
The present invention provides a kind of Ultramicro-powder cryogrinding technologies, comprising steps of Radix Notoginseng is using ultramicro grinding after will be dry
Machine is crushed, and superfine notoginseng powder is obtained；Wherein, in superfine notoginseng powder, the partial size for the particle that quality accounting is 98% or more is small
In 800 mesh；After drying Radix Notoginseng preparation method comprising steps of by fresh Roots of Panax Notoginseng using water carry out ultrasonic activation cleaning,
Then it dries, Radix Notoginseng after being dried.It should be noted that the Radix Notoginseng that the present invention uses refers to mountain of papers Radix Notoginseng, Yunnan text is originated in
Mountain state is panax araliaceae plant.
Preferably, the number of ultrasonic cleaning is 4 times, preceding ultrasonic cleaning twice be using conventional drinking water cleaning, after twice
Ultrasonic activation cleaning is cleaned using medical grade ion cleaning water.Ultrasonic activation is physical vibration, preceding to be cleaned by ultrasonic twice
The impurity such as the remaining soil of Panax notoginseng root can be effectively removed.
Preferably, for the power for the supersonic wave cleaning machine that ultrasonic activation cleaning uses for 240~300W, ultrasonic activation is clear
The time washed is 10~15min.
Preferably, dry include but is not limited to vacuum freezedrying, one of dry and dry or various ways.
Preferably, Radix Notoginseng is aqueous of low quality in 20% after drying, and the time of crushing is 2~10min, the temperature of crushing
Not higher than 0 DEG C.
Preferably, before being dried, further include the steps that handling the Roots of Panax Notoginseng after cleaning and draining: by draining
Roots of Panax Notoginseng afterwards is successively stood in first environment, in second environment and in third environment；Wherein, the gas packet in first environment
Include oxygen；Gas in second environment is air；Gas in third environment includes oxygen and ozone.
Preferably, in first environment: using daylight light irradiation, intensity of illumination is 500~600lux, and temperature is 25~30
DEG C, relative humidity is 2%~4%, and the concentration of gas is 0.9~1.2 μ L/L；The time stood in first environment be 120~
140h；In second environment: using wavelength to irradiate for the ultraviolet light source of 254nm, intensity of illumination is 800~1000lux, and temperature is
15~20 DEG C, relative humidity is 6%~8%；The time stood in second environment is 20~30min；In third environment: using
Daylight light irradiation, intensity of illumination are 200~300lux, and temperature is 2~4 DEG C, and relative humidity is 7%~8%, and the concentration of gas is
0.5~0.6 μ L/L；The time stood in third environment is 46~50h；Wherein, the molar ratio of oxygen and ozone is 1:(0.05
~0.1).
Preferably, further include the steps that carrying out superfine notoginseng powder it is closed seal up for safekeeping, it is closed seal up for safekeeping using vacuum packing machine into
Row；Closed seal up for safekeeping is to carry out closed seal up for safekeeping using vacuum tight PVC compound membrane bag.
The present invention also protects the superfine notoginseng powder being prepared according to the above method.
Technical solution provided by the invention, with following the utility model has the advantages that (1) present invention uses Ultramicro-powder cryogrinding skill
Art can operate fever to avoid machine at high speeds and break to pseudo-ginseng activity ingredient and mouthfeel by being crushed under cryogenic
It is bad, Radix Notoginseng natural taste and nutritive value are maintained to the maximum extent, and preparation process does not add any auxiliary material and anti-corrosion
Agent, pure green production, the superfine notoginseng powder being prepared are highly purified；(2) Radix Notoginseng after drying is carried out Ultramicro-powder by the present invention
Broken, obtained Ultramicro-powder is more easier to be dissolved in water, and is conducive to the dissolution of effective component, can more fully play the medicine of Radix Notoginseng
Effect；(3) present invention is packed using vacuum tightness method according to different specification grams, can satisfy depositing for superfine notoginseng powder
Storage demand；Processing method provided by the invention is simple, and production cost is low, has good commercial promise.
Additional aspect and advantage of the invention will be set forth in part in the description, and will partially become from the following description
Obviously, or practice through the invention is recognized.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical solution of the present invention is clearly and completely described.Implement below
Example is only used for clearly illustrating technical solution of the present invention, therefore is intended only as example, and cannot be used as a limitation and limit this hair
Bright protection scope.
Experimental method in following embodiments is unless otherwise specified conventional method.Examination as used in the following examples
Material is tested, is to be commercially available from regular shops unless otherwise specified.Quantitative test in following embodiment, is respectively provided with three
Secondary to repeat to test, data are the average value or mean+SD of three repeated experiments.
The present invention provides a kind of Ultramicro-powder cryogrinding technology, includes the following steps:
S1: fresh Roots of Panax Notoginseng is cleaned twice using conventional drinking water ultrasonic activation, every time 10~15min, then
It is cleaned twice using medical grade ion cleaning water draining ultrasonic activation, every time 10~15min；Wherein, supersonic wave cleaning machine
Power is 240~300W；
Preferably, further include the steps that by cleaning and draining after Roots of Panax Notoginseng handle: by the Roots of Panax Notoginseng after draining according to
It is secondary to be stood in first environment, in second environment and in third environment；Wherein, in first environment: using daylight light irradiation, illumination
Intensity is 500~600lux, and temperature is 25~30 DEG C, and relative humidity is 2%~4%, and the concentration of gas is 0.9~1.2 μ L/L,
Gas includes oxygen；The time stood in first environment is 120~140h；In second environment: using wavelength for the purple of 254nm
Outer lamp source irradiation, intensity of illumination are 800~1000lux, and temperature is 15~20 DEG C, and relative humidity is 6%~8%, and gas is
Air；The time stood in second environment is 20~30min；In third environment: using daylight light irradiation, intensity of illumination is
200~300lux, temperature are 2~4 DEG C, and relative humidity is 7%~8%, and the concentration of gas is 0.5~0.6 μ L/L；In third ring
The time stood in border is 46~50h；Wherein, gas includes oxygen and ozone, the molar ratio of oxygen and ozone be 1:(0.05~
0.1)；
S2: carrying out treated Radix Notoginseng vacuum freezedrying, dry or dry, obtains aqueous of low quality in 20%
Radix Notoginseng after drying；
S3: under conditions of temperature is lower than 0 DEG C, Radix Notoginseng after drying is crushed into 2~10min using micronizer, is obtained
Superfine notoginseng powder of the partial size for the particle that quality accounting is 98% or more less than 800 mesh；
S4: use vacuum tight PVC compound membrane bag, by superfine notoginseng powder be vacuum-packed machine carry out by weight it is closed
It seals up for safekeeping.
Technical solution provided by the invention is described further combined with specific embodiments below.
Embodiment one
The present embodiment provides a kind of Ultramicro-powder cryogrinding technologies, include the following steps:
S1: twice using conventional drinking water ultrasonic activation cleaning by fresh Roots of Panax Notoginseng, then each 12min is used
Medical grade ion cleaning water draining ultrasonic activation cleans twice, each 12min；Wherein, the power of supersonic wave cleaning machine is
270W；
By the Roots of Panax Notoginseng draining after cleaning, then successively stood in first environment, in second environment and in third environment,
The Radix Notoginseng that obtains that treated；Wherein, in first environment: daylight light irradiation, intensity of illumination 550lux are used, temperature is 27 DEG C,
Relative humidity is 3%, and the concentration of gas is 1.1 μ L/L, and gas includes oxygen；The time stood in first environment is 130h；
In second environment: using wavelength to irradiate for the ultraviolet light source of 254nm, intensity of illumination 900lux, temperature is 18 DEG C, relatively wet
Degree is 7%, and gas is air；The time stood in second environment is 25min；In third environment: using daylight light irradiation, light
It is 250lux according to intensity, temperature is 3 DEG C, and relative humidity 7.5%, the concentration of gas is 0.56 μ L/L；It is quiet in third environment
The time set is 48h；Wherein, gas includes oxygen and ozone, and the molar ratio of oxygen and ozone is 1:0.08；
S2: by treated, Radix Notoginseng carries out vacuum freezedrying, obtains the aqueous Radix Notoginseng of low quality after 13% drying；
S3: under conditions of temperature is lower than 0 DEG C, Radix Notoginseng after drying is crushed into 7min using micronizer, obtains quality
Superfine notoginseng powder of the partial size for the particle that accounting is 98% or more less than 800 mesh；
S4: use vacuum tight PVC compound membrane bag, by superfine notoginseng powder be vacuum-packed machine carry out by weight it is closed
It seals up for safekeeping.
Embodiment two
The present embodiment provides a kind of Ultramicro-powder cryogrinding technologies, include the following steps:
S1: twice using conventional drinking water ultrasonic activation cleaning by fresh Roots of Panax Notoginseng, then each 10min is used
Medical grade ion cleaning water draining ultrasonic activation cleans twice, each 10min；Wherein, the power of supersonic wave cleaning machine is
240W；
By the Roots of Panax Notoginseng draining after cleaning, then successively stood in first environment, in second environment and in third environment,
The Radix Notoginseng that obtains that treated；Wherein, in first environment: daylight light irradiation, intensity of illumination 500lux are used, temperature is 25 DEG C,
Relative humidity is 2%, and the concentration of gas is 0.9 μ L/L, and gas includes oxygen；The time stood in first environment is 120h；
In second environment: using wavelength to irradiate for the ultraviolet light source of 254nm, intensity of illumination 800lux, temperature is 15 DEG C, relatively wet
Degree is 6%, and gas is air；The time stood in second environment is 20min；In third environment: using daylight light irradiation, light
It is 200lux according to intensity, temperature is 2 DEG C, and relative humidity 7%, the concentration of gas is 0.5 μ L/L；It is stood in third environment
Time is 46h；Wherein, gas includes oxygen and ozone, and the molar ratio of oxygen and ozone is 1:0.05；
S2: by treated, Radix Notoginseng is dried, and obtains the aqueous Radix Notoginseng of low quality after 20% drying；
S3: under conditions of temperature is lower than 0 DEG C, Radix Notoginseng after drying is crushed into 2min using micronizer, obtains quality
Superfine notoginseng powder of the partial size for the particle that accounting is 98% or more less than 800 mesh；
S4: use vacuum tight PVC compound membrane bag, by superfine notoginseng powder be vacuum-packed machine carry out by weight it is closed
It seals up for safekeeping.
Embodiment three
The present embodiment provides a kind of Ultramicro-powder cryogrinding technologies, include the following steps:
S1: twice using conventional drinking water ultrasonic activation cleaning by fresh Roots of Panax Notoginseng, then each 15min is used
Medical grade ion cleaning water draining ultrasonic activation cleans twice, each 15min；Wherein, the power of supersonic wave cleaning machine is
300W；
By the Roots of Panax Notoginseng draining after cleaning, then successively stood in first environment, in second environment and in third environment,
The Radix Notoginseng that obtains that treated；Wherein, in first environment: daylight light irradiation, intensity of illumination 600lux are used, temperature is 30 DEG C,
Relative humidity is 4%, and the concentration of gas is 1.2 μ L/L, and gas includes oxygen；The time stood in first environment is 140h；
In second environment: using wavelength to irradiate for the ultraviolet light source of 254nm, intensity of illumination 1000lux, temperature is 20 DEG C, relatively
Humidity is 8%, and gas is air；The time stood in second environment is 30min；In third environment: daylight light irradiation is used,
Intensity of illumination is 300lux, and temperature is 4 DEG C, and relative humidity 8%, the concentration of gas is 0.6 μ L/L；It is stood in third environment
Time be 50h；Wherein, gas includes oxygen and ozone, and the molar ratio of oxygen and ozone is 1:0.1；
S2: by treated, Radix Notoginseng carries out vacuum freezedrying, obtains the aqueous Radix Notoginseng of low quality after 13% drying；
S3: under conditions of temperature is lower than 0 DEG C, Radix Notoginseng after drying is crushed into 10min using micronizer, obtains quality
Superfine notoginseng powder of the partial size for the particle that accounting is 98% or more less than 800 mesh；
S4: use vacuum tight PVC compound membrane bag, by superfine notoginseng powder be vacuum-packed machine carry out by weight it is closed
It seals up for safekeeping.
Comparative example one
This comparative example provides a kind of Ultramicro-powder cryogrinding technology, includes the following steps:
S1: twice using conventional drinking water ultrasonic activation cleaning by fresh Roots of Panax Notoginseng, then each 12min is used
Medical grade ion cleaning water draining ultrasonic activation cleans twice, each 12min；Wherein, the power of supersonic wave cleaning machine is
270W；
Then it successively stands in first environment and in third environment, the Roots of Panax Notoginseng draining after cleaning after obtaining processing
Radix Notoginseng；Wherein, in first environment: using daylight light irradiation, intensity of illumination 550lux, temperature is 27 DEG C, and relative humidity is
3%, the concentration of gas is 1.1 μ L/L, and gas includes oxygen；The time stood in first environment is 130h；In third environment:
Using daylight light irradiation, intensity of illumination 250lux, temperature is 3 DEG C, relative humidity 7.5%, and the concentration of gas is 0.56 μ L/
L；The time stood in third environment is 48h；Wherein, gas includes oxygen and ozone, and the molar ratio of oxygen and ozone is 1:
0.08；
S2: by treated, Radix Notoginseng carries out vacuum freezedrying, obtains the aqueous Radix Notoginseng of low quality after 13% drying；
S3: under conditions of temperature is lower than 0 DEG C, Radix Notoginseng after drying is crushed into 7min using micronizer, obtains quality
Superfine notoginseng powder of the partial size for the particle that accounting is 98% or more less than 800 mesh；
S4: use vacuum tight PVC compound membrane bag, by superfine notoginseng powder be vacuum-packed machine carry out by weight it is closed
It seals up for safekeeping.
Comparative example two
This comparative example provides a kind of Ultramicro-powder cryogrinding technology, includes the following steps:
S1: twice using conventional drinking water ultrasonic activation cleaning by fresh Roots of Panax Notoginseng, then each 12min is used
Medical grade ion cleaning water draining ultrasonic activation cleans twice, each 12min；Wherein, the power of supersonic wave cleaning machine is
270W；
Then it successively stands in first environment and in second environment, the Roots of Panax Notoginseng draining after cleaning after obtaining processing
Radix Notoginseng；Wherein, in first environment: using daylight light irradiation, intensity of illumination 550lux, temperature is 27 DEG C, and relative humidity is
3%, the concentration of gas is 1.1 μ L/L, and gas includes oxygen；The time stood in first environment is 130h；In second environment:
Wavelength is used to irradiate for the ultraviolet light source of 254nm, intensity of illumination 900lux, temperature is 18 DEG C, relative humidity 7%, gas
Body is air；The time stood in second environment is 25min；
S2: by treated, Radix Notoginseng carries out vacuum freezedrying, obtains the aqueous Radix Notoginseng of low quality after 13% drying；
S3: under conditions of temperature is lower than 0 DEG C, Radix Notoginseng after drying is crushed into 7min using micronizer, obtains quality
Superfine notoginseng powder of the partial size for the particle that accounting is 98% or more less than 800 mesh；
S4: use vacuum tight PVC compound membrane bag, by superfine notoginseng powder be vacuum-packed machine carry out by weight it is closed
It seals up for safekeeping.
Comparative example three
This comparative example provides a kind of Ultramicro-powder cryogrinding technology, includes the following steps:
S1: twice using conventional drinking water ultrasonic activation cleaning by fresh Roots of Panax Notoginseng, then each 12min is used
Medical grade ion cleaning water draining ultrasonic activation cleans twice, each 12min；Wherein, the power of supersonic wave cleaning machine is
270W；
Then it successively stands in second environment and in third environment, the Roots of Panax Notoginseng draining after cleaning after obtaining processing
Radix Notoginseng；Wherein, in second environment: use wavelength to irradiate for the ultraviolet light source of 254nm, intensity of illumination 900lux, temperature
It is 18 DEG C, relative humidity 7%, gas is air；The time stood in second environment is 25min；In third environment: using
Daylight light irradiation, intensity of illumination 250lux, temperature are 3 DEG C, and relative humidity 7.5%, the concentration of gas is 0.56 μ L/L；?
The time stood in third environment is 48h；Wherein, gas includes oxygen and ozone, and the molar ratio of oxygen and ozone is 1:0.08；
S2: by treated, Radix Notoginseng carries out vacuum freezedrying, obtains the aqueous Radix Notoginseng of low quality after 13% drying；
S3: under conditions of temperature is lower than 0 DEG C, Radix Notoginseng after drying is crushed into 7min using micronizer, obtains quality
Superfine notoginseng powder of the partial size for the particle that accounting is 98% or more less than 800 mesh；
S4: use vacuum tight PVC compound membrane bag, by superfine notoginseng powder be vacuum-packed machine carry out by weight it is closed
It seals up for safekeeping.
The superfine notoginseng powder that the present invention is prepared, by function assessment test come its performance of system evaluation, and with right
The superfine notoginseng powder that ratio one is prepared to comparative example three.
1, storage effect
Superfine notoginseng powder and comparative example one to comparative example three that embodiment one to embodiment three is prepared are prepared
Superfine notoginseng powder carry out the measurement of total number of bacteria respectively, the time point of measurement be it is closed seal up for safekeeping 1 month, 3 months, 6 months and
12 months, the concrete outcome of measurement was as shown in table 1 below.
1 storage effect of table
2, the effect of superfine notoginseng powder reducing blood lipid
Selecting weight is the small white mouse 80 (each 40 of male and female) of 18~22g, is divided into 8 groups, is denoted as A-H group respectively, every group female
Male each 5.A group is set as control group, normal pill feed is provided；B group is set as high blood lipid model group, provides the high lipid of autogamy and raises
Material；Stomach-filling gives the 2g/kg embodiment of the present invention one to embodiment three, comparison to C-H group when providing hyperlipidemia diet, while respectively
The superfine notoginseng powder that example one is prepared to comparative example three；It is grouped cage, drinking-water of freely ingesting.Once a day, continuous 30 days, in
Last is taken a blood sample on an empty stomach to next day after Ultramicro-powder, measures serum total cholesterol (TC), triglycerides (TG), high-density lipoprotein
(HDL) and low-density lipoprotein (LDL) is horizontal, and concrete outcome is as shown in table 2.
Influence of 2 superfine notoginseng powder of table to hyperlipemia small white mouse blood lipid level
The present invention can be to avoid machine height by being crushed under cryogenic using Ultramicro-powder cryogrinding technology
Destruction of the speed operating fever to pseudo-ginseng activity ingredient and mouthfeel, maintains Radix Notoginseng natural taste and nutriture value to the maximum extent
Value, and preparation process does not add any auxiliary material and preservative, and pure green produces, and the superfine notoginseng powder height being prepared is pure
Change；The present invention pulverizes the Radix Notoginseng after drying, and obtained Ultramicro-powder is more easier to be dissolved in water, and is conducive to effectively
The dissolution of ingredient can more fully play the drug effect of Radix Notoginseng；The present invention is using vacuum tightness method according to different specification grams
It is packed, can satisfy the storage demand of superfine notoginseng powder；Processing method provided by the invention is simple, and production cost is low, tool
There is good commercial promise.
It should be noted that unless otherwise indicated, technical term or scientific term used in this application should be this hair
The ordinary meaning that bright one of ordinary skill in the art are understood.Unless specifically stated otherwise, it otherwise illustrates in these embodiments
Component and opposite step, numerical expression and the numerical value of step are not limit the scope of the invention.It is illustrated and described herein
In all examples, unless otherwise prescribed, any occurrence should be construed as merely illustratively, not as limitation, because
This, other examples of exemplary embodiment can have different values.
In the description of the present invention, it is to be understood that, term " first ", " second " are used for description purposes only, and cannot
It is interpreted as indication or suggestion relative importance or implicitly indicates the quantity of indicated technical characteristic.Define as a result, " the
One ", the feature of " second " can explicitly or implicitly include one or more of the features.In the description of the present invention,
The meaning of " plurality " is two or more, unless otherwise specifically defined.
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent
Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to
So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into
Row equivalent replacement；And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme should all cover in protection scope of the present invention.
Claims (9)
1. a kind of Ultramicro-powder cryogrinding technology, which is characterized in that comprising steps of
Radix Notoginseng after drying is crushed using micronizer, obtains superfine notoginseng powder；
Wherein, in the superfine notoginseng powder, the partial size for the particle that quality accounting is 98% or more is less than 800 mesh；
After the drying Radix Notoginseng preparation method comprising steps of by fresh Roots of Panax Notoginseng using water carry out ultrasonic activation cleaning,
Then it dries, obtains Radix Notoginseng after the drying.
2. Ultramicro-powder cryogrinding technology according to claim 1, it is characterised in that:
The number of the ultrasonic activation cleaning is 4 times, and the preceding cleaning of ultrasonic activation twice is to use conventional drinking water cleaning, after
Ultrasonic activation cleaning twice is cleaned using medical grade ion cleaning water.
3. Ultramicro-powder cryogrinding technology according to claim 2, it is characterised in that:
The power for the supersonic wave cleaning machine that the ultrasonic activation cleaning uses is 240~300W, the ultrasonic activation cleaning
Time be 10~15min.
4. Ultramicro-powder cryogrinding technology according to claim 1, it is characterised in that:
The drying includes but is not limited to vacuum freezedrying, one of dries and dries or various ways.
5. Ultramicro-powder cryogrinding technology according to claim 1, it is characterised in that:
Radix Notoginseng is aqueous of low quality in 20% after the drying, and the time of the crushing is 2~10min, the temperature of the crushing
Degree is not higher than 0 DEG C.
6. Ultramicro-powder cryogrinding technology according to claim 1, it is characterised in that:
Before carrying out the drying, further include the steps that handling the Roots of Panax Notoginseng after cleaning and draining: by three after draining
Seven successively stand in first environment, in second environment and in third environment；Wherein, the gas in the first environment includes
Oxygen；Gas in the second environment is air；Gas in the third environment includes oxygen and ozone.
7. Ultramicro-powder cryogrinding technology according to claim 6, it is characterised in that:
In the first environment: using daylight light irradiation, intensity of illumination is 500~600lux, and temperature is 25~30 DEG C, relatively wet
Degree is 2%~4%, and the concentration of gas is 0.9~1.2 μ L/L；The time stood in the first environment is 120~140h；
In the second environment: using wavelength to irradiate for the ultraviolet light source of 254nm, intensity of illumination is 800~1000lux, temperature
Degree is 15~20 DEG C, and relative humidity is 6%~8%；The time stood in the second environment is 20~30min；
In the third environment: using daylight light irradiation, intensity of illumination is 200~300lux, and temperature is 2~4 DEG C, relative humidity
It is 7%~8%, the concentration of gas is 0.5~0.6 μ L/L；The time stood in the third environment is 46~50h；Wherein,
The molar ratio of the oxygen and the ozone is 1:(0.05~0.1).
8. Ultramicro-powder cryogrinding technology according to claim 1, it is characterised in that:
Further include the steps that by the superfine notoginseng powder carry out it is closed seal up for safekeeping, closed seal up for safekeeping is carried out using vacuum packing machine；
Closed seal up for safekeeping is to carry out closed seal up for safekeeping using vacuum tight PVC compound membrane bag.
9. the superfine notoginseng powder that the described in any item technologies of claim 1-8 are prepared.
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Application publication date: 20190111 |