CN109125150A - A kind of skin care item and the preparation method and application thereof containing hawthorne leaf P.E - Google Patents

A kind of skin care item and the preparation method and application thereof containing hawthorne leaf P.E Download PDF

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CN109125150A
CN109125150A CN201710451390.8A CN201710451390A CN109125150A CN 109125150 A CN109125150 A CN 109125150A CN 201710451390 A CN201710451390 A CN 201710451390A CN 109125150 A CN109125150 A CN 109125150A
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leaves
hawthorn
skin care
leaf
purslane
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宋小锋
原增艳
杜晓娜
陶娟
刘瑞
刘仲敏
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Sanquan College of Xinxiang Medical University
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Sanquan College of Xinxiang Medical University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88Polyamides
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
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    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

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Abstract

The present invention relates to skin care field, specifically, it is related to a kind of skin care item and the preparation method and application thereof containing hawthorne leaf P.E, including each component measured by mass percentage as follows: leaves of Hawthorn composite vegetables extractive 10~15%, glycerol 3~6%, propylene glycol 3~5%, gamma-polyglutamic acid 3~5%, trehalose 2~5%, triethanolamine 0.5~1.0%, d- alpha-tocopherol 0.2~0.8%, hyaluronic acid 0.05~0.1%, methylparaben 0.05~0.1%, deionized water adds to 100%, and the process that homogeneous is extracted, mixed using compound is made.A kind of skin care item containing hawthorne leaf P.E provided by the invention and the preparation method and application thereof, which have, to be used based on natural plant composition and Chinese herbal medicine active constituent, have effects that nti-freckle, whitening and removes free radical, the calmness of pigment can be changed from cellular level, using safe, there is the extremely low advantage of the probability of adverse reaction.

Description

A kind of skin care item and the preparation method and application thereof containing hawthorne leaf P.E
Technical field
The present invention relates to skin care field, specifically, is related to a kind of skin care item containing hawthorne leaf P.E and its preparation Method and application.
Background technique
Color spot, that is, cutaneous pigmentation is led to hyperpigmentation in skin by a variety of causes and can not be metabolized in time and cause black Element is calm and is unevenly distributed, and performance is the flecks such as black, yellowish-brown on the skin.Due to adding for modern people's rhythm of life Fastly, and by various environment it is influenced, skin epidermis is easier to accumulate calmness, and the accumulation of the extra superoxide radical of skin causes It is easy long spot and aging becomes apparent from.
It is found through market survey, in Asia beauty and skin care market, freckle removing and whitening is still consumption mainstream.Traditional freckle removing and whitening Product is in the majority with chemical whitening agent, although effect is obvious, does not change the calmness of pigment from cellular level, and occur in safety The probability of adverse reaction is relatively high, may cause the irreversible damage of skin when serious.Natural plant composition nti-freckle and anti-oxidant Sensitization rate is low, highly-safe, is increasingly becoming advocating for consumer.Therefore, it needs in the market a kind of using natural plant composition And based on Chinese herbal medicine active constituent, have effects that nti-freckle, whitening and the skin care item for removing free radical.
Summary of the invention
The present invention be solve it is existing with nti-freckle, white-skinned face function chemical skin care item have without changing from cellular level Change colour plain calmness, and the probability for occurring adverse reaction in safety is relatively high, may cause the irreversible damage of skin when serious The problem of, and provide and use based on natural plant composition and Chinese herbal medicine active constituent, there is nti-freckle, whitening and remove free radical The effect of a kind of skin care item and the preparation method and application thereof containing hawthorne leaf P.E.
The technical solution adopted by the present invention is that:
A kind of skin care item containing hawthorne leaf P.E, including each component measured by mass percentage as follows: leaves of Hawthorn Composite vegetables extractive 10~15%, glycerol 3~6%, propylene glycol 3~5%, gamma-polyglutamic acid 3~5%, trehalose 2~ 5%, triethanolamine 0.5~1.0%, d- alpha-tocopherol 0.2~0.8%, hyaluronic acid 0.05~0.1%, methylparaben 0.05~0.1%, deionized water adds to 100%;
The leaves of Hawthorn composite vegetables extractive be the leaves of Hawthorn measured according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, Granatum, peppermint, the root of Dahurain angelica, purslane various plants, the extracted, compound extract that is prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%.
A kind of skin care item containing leaves of Hawthorn composite vegetables extractive, including each group measured by mass percentage as follows Point: leaves of Hawthorn composite vegetables extractive 11~14%, glycerol 4~5%, propylene glycol 3.5~4.5%, gamma-polyglutamic acid 3.5~ 4.5%, trehalose 3~4%, triethanolamine 0.65~0.85%, d- alpha-tocopherol 0.4~0.6%, hyaluronic acid 0.065~ 0.05%, methylparaben 0.065~0.085%, deionized water add to 100%;
The leaves of Hawthorn composite vegetables extractive be the leaves of Hawthorn measured according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, Granatum, peppermint, the root of Dahurain angelica, purslane various plants, the extracted, compound extract that is prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%.
A kind of skin care item containing leaves of Hawthorn composite vegetables extractive, including each group measured by mass percentage as follows Point: leaves of Hawthorn composite vegetables extractive 12.5%, glycerol 4.5%, propylene glycol 4%, gamma-polyglutamic acid 4%, trehalose 3.5%, Triethanolamine 0.75%, d- alpha-tocopherol 0.5%, hyaluronic acid 0.075%, methylparaben 0.075%, deionized water adds to 100%;
The leaves of Hawthorn composite vegetables extractive be the leaves of Hawthorn measured according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, Granatum, peppermint, the root of Dahurain angelica, purslane various plants, the extracted, compound extract that is prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%.
A kind of preparation method of the skin care item containing hawthorn leaf plant extract, preparation method are as follows:
Step 1) is measured according to the mass percent of each component described in the claims, takes out leaves of Hawthorn, sweet Grass, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane extract to obtain leaves of Hawthorn composite vegetables extractive by ethyl alcohol, spare;
Step 2) is measured according to the mass percent of each component described in the claims, is taken out in step 1) and is obtained Leaves of Hawthorn composite vegetables extractive and glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, the d- α-fertility arrived Phenol, hyaluronic acid, methylparaben and deionized water, it is spare;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), is sequentially added Deionized water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Close object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 Homogeneous is uniformly mixed under the conditions of DEG C, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains A group raw mixture by step 5) Interior, homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under room temperature.
Further, it states in step 1) and leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, horse is extracted by ethyl alcohol Bitterroot, the method for obtaining leaves of Hawthorn composite vegetables extractive are as follows: take leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, Purslane, adds 50% (V/V) edible alcohol, and 50% (V/V) edible alcohol quality is leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, pomegranate Skin, peppermint, the root of Dahurain angelica, 8 times of gross mass of purslane, extract 2 hours under the conditions of 55~65 DEG C, collect after being filtered to remove filter residue Filtrate, similarity condition extract twice altogether, merging filtrate, recovered alcohol are concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with The pure water dilution of remaining extracting solution same volume, by D101 large pore resin absorption column, successively spends after concentration and recovery ethyl alcohol Ionized water and 50% edible alcohol elution, collect and merge eluent after corresponding eluent, centrifugation removal insoluble matter, 60 DEG C of items Vacuum-concentrcted is to the clear cream of relative density about 1.15~1.20 to get leaves of Hawthorn composite vegetables extractive under part.
A kind of application of the skin care item containing hawthorne leaf P.E: the skin care item are preparing face cream or skin care hair gel cream In application.
The beneficial effects of the present invention are:
A kind of skin care item and the preparation method and application thereof containing hawthorne leaf P.E provided by the invention, for color spot Formation mechenism is first had to accelerate melanin metabolism using combination of Chinese tradiational and Western medicine method dispelling stain, inhibits epidermis thin from cellular level Extra superoxide radical is removed in the formation of born of the same parents' melanin.Beneficial effects of the present invention are that skin epidermis blood vessel can be promoted micro- Circulation accelerates melanin metabolism, effectively removing superoxide radical, dispels or desalinate skin splash, anti-oxidant delay skin aging. It is tested by the detection of effective component, flavonoids rich in skin care item provided by the invention, tannins, phenols and more Kind microelement.The present invention refers to the Chinese medicine compatibility theory of monarch, and leaves of Hawthorn and ginkgo leaf total flavonoid all have promoting blood circulationization The effect of stasis of blood, qi-regulating are promoted blood circulation can enhance antiotasis, can promote superficial vessels microcirculation, accelerate melanin metabolism discharge In vitro, while there is the ability for removing the extra superoxide radical of skin.Active constituent liquiritin is to tyrosine in licorice The inhibition of enzyme and the inhibition of dopachrome isomerase activity inhibit epidermal cell to generate melanin.Clinical research shows granatum In extract active constituent tannin and tocopherol all have it is anti-oxidant, delay senescence the effect of.The root of Dahurain angelica, purslane are extracted Object flavonoids and phenolic substances have effects that inhibiting bacteria and diminishing inflammation, soothe the skin, resist environmental stimuli.Mint extract Peppermint essential oil Expansion capillary of skin can promote other functional components to play effect.Gamma-polyglutamic acid has good moistening effect.
It is adopted in short, a kind of skin care item containing hawthorne leaf P.E provided by the invention and the preparation method and application thereof have Based on natural plant composition and Chinese herbal medicine active constituent, has effects that nti-freckle, whitening and remove free radical, it can be from thin Born of the same parents' level changes the calmness of pigment, and use is safe, the extremely low advantage of the probability of adverse reaction occurs.
Specific embodiment
Core of the invention is to provide a kind of skin care item and the preparation method and application thereof containing hawthorne leaf P.E.
Embodiment 1, a kind of skin care item containing hawthorne leaf P.E, including each component measured by mass percentage: mountain Short, bristly hair or beard leaf composite vegetables extractive 14.5%, glycerol 5%, propylene glycol 5%, gamma-polyglutamic acid 5%, trehalose 5%, triethanolamine 0.9%, d- alpha-tocopherol 0.7%, hyaluronic acid 0.08%, methylparaben 0.1%, deionized water 63.72%;Wherein, mountain Short, bristly hair or beard leaf composite vegetables extractive is each component measured according to following mass percent, extracted, be prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;
Using above-mentioned formula a kind of skin care item containing hawthorne leaf P.E specific the preparation method is as follows:
Step 1), the leaves of Hawthorn for taking out corrresponding quality respectively according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, granatum, Peppermint, the root of Dahurain angelica, purslane, it is spare;Wherein, leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;By leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane, add 50% (V/V) edible alcohol, 50% (V/V) edible alcohol quality being added is leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, granatum, thin Lotus, the root of Dahurain angelica, 8 times of purslane gross mass, extract 2 hours under the conditions of 55 DEG C, collect filtrate, same batten after being filtered to remove filter residue Part extracts twice altogether, merging filtrate, recovered alcohol is concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with concentration and recovery ethyl alcohol The pure water dilution of remaining extracting solution same volume successively uses deionized water and 50% by D101 large pore resin absorption column afterwards Edible alcohol elution, collect and merge eluent after corresponding eluent, centrifugation removal insoluble matter, vacuum decompression under the conditions of 60 DEG C It is concentrated into the clear cream of relative density about 1.15, obtains leaves of Hawthorn composite vegetables extractive, it is spare;
Step 2) takes out leaves of Hawthorn composite vegetables extractive obtained in step 1) according to following mass percent respectively, And glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, d- alpha-tocopherol, hyaluronic acid, methylparaben and Deionized water, it is spare;Wherein, leaves of Hawthorn composite vegetables extractive 14.5%, glycerol 5%, propylene glycol 5%, gamma-polyglutamic acid 5%, trehalose 5%, triethanolamine 0.9%, d- alpha-tocopherol 0.7%, hyaluronic acid 0.08%, methylparaben 0.1% are gone Ionized water 63.72%;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), is sequentially added Deionized water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Close object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 Homogeneous is uniformly mixed under the conditions of DEG C, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains A group raw mixture by step 5) Interior, homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under room temperature.
The skin care item are manufactured using the technique, can ensure that the quality and effect of skin care item, and non-stimulated to skin.It adopts The skin care item being prepared in aforementioned manners can be used in preparing face cream or skin care hair gel cream.
Embodiment 2, a kind of skin care item containing hawthorne leaf P.E, including each component measured by mass percentage: mountain Short, bristly hair or beard leaf composite vegetables extractive 13%, glycerol 5%, propylene glycol 4%, gamma-polyglutamic acid 4%, trehalose 4%, triethanolamine 0.8%, d- alpha-tocopherol 0.5%, hyaluronic acid 0.08%, methylparaben 0.08%, deionized water 68.54%;Wherein, mountain Short, bristly hair or beard leaf composite vegetables extractive is each component measured according to following mass percent, extracted, be prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;
Using above-mentioned formula a kind of skin care item containing hawthorne leaf P.E specific the preparation method is as follows:
Step 1), the leaves of Hawthorn for taking out corrresponding quality respectively according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, granatum, Peppermint, the root of Dahurain angelica, purslane, it is spare;Wherein, leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;By leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane, add 50% (V/V) edible alcohol, 50% (V/V) edible alcohol quality being added is leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, granatum, thin Lotus, the root of Dahurain angelica, 8 times of purslane gross mass, extract 2 hours under the conditions of 60 DEG C, collect filtrate, same batten after being filtered to remove filter residue Part extracts twice altogether, merging filtrate, recovered alcohol is concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with concentration and recovery ethyl alcohol The pure water dilution of remaining extracting solution same volume successively uses deionized water and 50% by D101 large pore resin absorption column afterwards Edible alcohol elution, collect and merge eluent after corresponding eluent, centrifugation removal insoluble matter, vacuum decompression under the conditions of 60 DEG C It is concentrated into the clear cream of relative density about 1.17, obtains leaves of Hawthorn composite vegetables extractive, it is spare;
Step 2) takes out leaves of Hawthorn composite vegetables extractive obtained in step 1) according to following mass percent respectively, And glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, d- alpha-tocopherol, hyaluronic acid, methylparaben and Deionized water, it is spare;Wherein, leaves of Hawthorn composite vegetables extractive 13%, glycerol 5%, propylene glycol 4%, gamma-polyglutamic acid 4%, Trehalose 4%, triethanolamine 0.8%, d- alpha-tocopherol 0.5%, hyaluronic acid 0.08%, methylparaben 0.08%, go from Sub- water 68.54%;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), is sequentially added Deionized water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Close object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 Homogeneous is uniformly mixed under the conditions of DEG C, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains A group raw mixture by step 5) Interior, homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under room temperature.
The skin care item are manufactured using the technique, can ensure that the quality and effect of skin care item, and non-stimulated to skin.It adopts The skin care item being prepared in aforementioned manners can be used in preparing face cream or skin care hair gel cream.
Embodiment 3, a kind of skin care item containing hawthorne leaf P.E, including each component measured by mass percentage: mountain Short, bristly hair or beard leaf composite vegetables extractive 11%, glycerol 5%, propylene glycol 5%, gamma-polyglutamic acid 5%, trehalose 4%, triethanolamine 1.0%, d- alpha-tocopherol 0.5%, hyaluronic acid 0.05%, methylparaben 0.05%, deionized water 68.4%;Wherein, mountain Short, bristly hair or beard leaf composite vegetables extractive is each component measured according to following mass percent, extracted, be prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;
Using above-mentioned formula a kind of skin care item containing hawthorne leaf P.E specific the preparation method is as follows:
Step 1), the leaves of Hawthorn for taking out corrresponding quality respectively according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, granatum, Peppermint, the root of Dahurain angelica, purslane, it is spare;Wherein, leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;By leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane, add 50% (V/V) edible alcohol, 50% (V/V) edible alcohol quality being added is leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, granatum, thin Lotus, the root of Dahurain angelica, 8 times of purslane gross mass, extract 2 hours under the conditions of 63 DEG C, collect filtrate, same batten after being filtered to remove filter residue Part extracts twice altogether, merging filtrate, recovered alcohol is concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with concentration and recovery ethyl alcohol The pure water dilution of remaining extracting solution same volume successively uses deionized water and 50% by D101 large pore resin absorption column afterwards Edible alcohol elution, collect and merge eluent after corresponding eluent, centrifugation removal insoluble matter, vacuum decompression under the conditions of 60 DEG C It is concentrated into the clear cream of relative density about 1.19, obtains leaves of Hawthorn composite vegetables extractive, it is spare;
Step 2) takes out leaves of Hawthorn composite vegetables extractive obtained in step 1) according to following mass percent respectively, And glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, d- alpha-tocopherol, hyaluronic acid, methylparaben and Deionized water, it is spare;Wherein, leaves of Hawthorn composite vegetables extractive 11%, glycerol 5%, propylene glycol 5%, gamma-polyglutamic acid 5%, Trehalose 4%, triethanolamine 1.0%, d- alpha-tocopherol 0.5%, hyaluronic acid 0.05%, methylparaben 0.05%, go from Sub- water 68.4%;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), is sequentially added Deionized water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Close object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 Homogeneous is uniformly mixed under the conditions of DEG C, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains A group raw mixture by step 5) Interior, homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under room temperature.
The skin care item are manufactured using the technique, can ensure that the quality and effect of skin care item, and non-stimulated to skin.It adopts The skin care item being prepared in aforementioned manners can be used in preparing face cream or skin care hair gel cream.
Embodiment 4, a kind of skin care item containing hawthorne leaf P.E, including each component measured by mass percentage: mountain Short, bristly hair or beard leaf composite vegetables extractive 12.5%, glycerol 4.5%, propylene glycol 4%, gamma-polyglutamic acid 4%, trehalose 3.5%, three second Hydramine 0.75%, d- alpha-tocopherol 0.5%, hyaluronic acid 0.075%, methylparaben 0.075%, deionized water 70.1%; Wherein, leaves of Hawthorn composite vegetables extractive is each component measured according to following mass percent, extracted, be prepared: mountain Short, bristly hair or beard leaf 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;
Using above-mentioned formula a kind of skin care item containing hawthorne leaf P.E specific the preparation method is as follows:
Step 1), the leaves of Hawthorn for taking out corrresponding quality respectively according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, granatum, Peppermint, the root of Dahurain angelica, purslane, it is spare;Wherein, leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;By leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane, add 50% (V/V) edible alcohol, 50% (V/V) edible alcohol quality being added is leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, granatum, thin Lotus, the root of Dahurain angelica, 8 times of purslane gross mass, extract 2 hours under the conditions of 65 DEG C, collect filtrate, same batten after being filtered to remove filter residue Part extracts twice altogether, merging filtrate, recovered alcohol is concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with concentration and recovery ethyl alcohol The pure water dilution of remaining extracting solution same volume successively uses deionized water and 50% by D101 large pore resin absorption column afterwards Edible alcohol elution, collect and merge eluent after corresponding eluent, centrifugation removal insoluble matter, vacuum decompression under the conditions of 60 DEG C It is concentrated into the clear cream of relative density about 1.16, obtains leaves of Hawthorn composite vegetables extractive, it is spare;
Step 2) takes out leaves of Hawthorn composite vegetables extractive obtained in step 1) according to following mass percent respectively, And glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, d- alpha-tocopherol, hyaluronic acid, methylparaben and Deionized water, it is spare;Wherein, leaves of Hawthorn composite vegetables extractive 12.5%, glycerol 4.5%, propylene glycol 4%, gamma-polyglutamic acid 4%, trehalose 3.5%, triethanolamine 0.75%, d- alpha-tocopherol 0.5%, hyaluronic acid 0.075%, methylparaben 0.075%, deionized water 70.1%;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), is sequentially added Deionized water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Close object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 Homogeneous is uniformly mixed under the conditions of DEG C, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains A group raw mixture by step 5) Interior, homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under room temperature.
The skin care item are manufactured using the technique, can ensure that the quality and effect of skin care item, and non-stimulated to skin.It adopts The skin care item being prepared in aforementioned manners can be used in preparing face cream or skin care hair gel cream.
Embodiment 5, a kind of skin care item containing hawthorne leaf P.E, including each component measured by mass percentage: mountain Short, bristly hair or beard leaf composite vegetables extractive 10%, glycerol 6%, propylene glycol 3.5%, gamma-polyglutamic acid 3.5%, trehalose 5%, three ethyl alcohol Amine 0.65%, d- alpha-tocopherol 0.8%, hyaluronic acid 0.1%, methylparaben 0.1%, deionized water 70.35%;Wherein, Leaves of Hawthorn composite vegetables extractive is each component measured according to following mass percent, extracted, be prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;
Using above-mentioned formula a kind of skin care item containing hawthorne leaf P.E specific the preparation method is as follows:
Step 1), the leaves of Hawthorn for taking out corrresponding quality respectively according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, granatum, Peppermint, the root of Dahurain angelica, purslane, it is spare;Wherein, leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;By leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane, add 50% (V/V) edible alcohol, 50% (V/V) edible alcohol quality being added is leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, granatum, thin Lotus, the root of Dahurain angelica, 8 times of purslane gross mass, extract 2 hours under the conditions of 65 DEG C, collect filtrate, same batten after being filtered to remove filter residue Part extracts twice altogether, merging filtrate, recovered alcohol is concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with concentration and recovery ethyl alcohol The pure water dilution of remaining extracting solution same volume successively uses deionized water and 50% by D101 large pore resin absorption column afterwards Edible alcohol elution, collect and merge eluent after corresponding eluent, centrifugation removal insoluble matter, vacuum decompression under the conditions of 60 DEG C It is concentrated into the clear cream of relative density about 1.18, obtains leaves of Hawthorn composite vegetables extractive, it is spare;
Step 2) takes out leaves of Hawthorn composite vegetables extractive obtained in step 1) according to following mass percent respectively, And glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, d- alpha-tocopherol, hyaluronic acid, methylparaben and Deionized water, it is spare;Wherein, leaves of Hawthorn composite vegetables extractive 10%, glycerol 6%, propylene glycol 3.5%, gamma-polyglutamic acid 3.5%, trehalose 5%, triethanolamine 0.65%, d- alpha-tocopherol 0.8%, hyaluronic acid 0.1%, methylparaben 0.1%, Deionized water 70.35%;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), is sequentially added Deionized water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Close object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 Homogeneous is uniformly mixed under the conditions of DEG C, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains A group raw mixture by step 5) Interior, homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under room temperature.
The skin care item are manufactured using the technique, can ensure that the quality and effect of skin care item, and non-stimulated to skin.It adopts The skin care item being prepared in aforementioned manners can be used in preparing face cream or skin care hair gel cream.
Embodiment 6, a kind of skin care item containing hawthorne leaf P.E, including each component measured by mass percentage: mountain Short, bristly hair or beard leaf composite vegetables extractive 15%, glycerol 3%, propylene glycol 3%, gamma-polyglutamic acid 4.5%, trehalose 3%, triethanolamine 0.85%, d- alpha-tocopherol 0.4%, hyaluronic acid 0.065%, methylparaben 0.065%, deionized water 70.12%;Its In, leaves of Hawthorn composite vegetables extractive is each component measured according to following mass percent, extracted, be prepared: hawthorn Leaf 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;
Using above-mentioned formula a kind of skin care item containing hawthorne leaf P.E specific the preparation method is as follows:
Step 1), the leaves of Hawthorn for taking out corrresponding quality respectively according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, granatum, Peppermint, the root of Dahurain angelica, purslane, it is spare;Wherein, leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;By leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane, add 50% (V/V) edible alcohol, 50% (V/V) edible alcohol quality being added is leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, granatum, thin Lotus, the root of Dahurain angelica, 8 times of purslane gross mass, extract 2 hours under the conditions of 58 DEG C, collect filtrate, same batten after being filtered to remove filter residue Part extracts twice altogether, merging filtrate, recovered alcohol is concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with concentration and recovery ethyl alcohol The pure water dilution of remaining extracting solution same volume successively uses deionized water and 50% by D101 large pore resin absorption column afterwards Edible alcohol elution, collect and merge eluent after corresponding eluent, centrifugation removal insoluble matter, vacuum decompression under the conditions of 60 DEG C It is concentrated into the clear cream of relative density about 1.20, obtains leaves of Hawthorn composite vegetables extractive, it is spare;
Step 2) takes out leaves of Hawthorn composite vegetables extractive obtained in step 1) according to following mass percent respectively, And glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, d- alpha-tocopherol, hyaluronic acid, methylparaben and Deionized water, it is spare;Wherein, leaves of Hawthorn composite vegetables extractive 15%, glycerol 3%, propylene glycol 3%, gamma-polyglutamic acid 4.5%, trehalose 3%, triethanolamine 0.85%, d- alpha-tocopherol 0.4%, hyaluronic acid 0.065%, methylparaben 0.065%, deionized water 70.12%;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), is sequentially added Deionized water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Close object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 Homogeneous is uniformly mixed under the conditions of DEG C, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains A group raw mixture by step 5) Interior, homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under room temperature.
The skin care item are manufactured using the technique, can ensure that the quality and effect of skin care item, and non-stimulated to skin.It adopts The skin care item being prepared in aforementioned manners can be used in preparing face cream or skin care hair gel cream.
Embodiment 7, a kind of skin care item containing hawthorne leaf P.E, including each component measured by mass percentage: mountain Short, bristly hair or beard leaf composite vegetables extractive 14%, glycerol 4%, propylene glycol 4.5%, gamma-polyglutamic acid 3%, trehalose 2%, triethanolamine 0.5%, d- alpha-tocopherol 0.6%, hyaluronic acid 0.085%, methylparaben 0.085%, deionized water 71.23%;Wherein, Leaves of Hawthorn composite vegetables extractive is each component measured according to following mass percent, extracted, be prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;
Using above-mentioned formula a kind of skin care item containing hawthorne leaf P.E specific the preparation method is as follows:
Step 1), the leaves of Hawthorn for taking out corrresponding quality respectively according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, granatum, Peppermint, the root of Dahurain angelica, purslane, it is spare;Wherein, leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;By leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane, add 50% (V/V) edible alcohol, 50% (V/V) edible alcohol quality being added is leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, granatum, thin Lotus, the root of Dahurain angelica, 8 times of purslane gross mass, extract 2 hours under the conditions of 57 DEG C, collect filtrate, same batten after being filtered to remove filter residue Part extracts twice altogether, merging filtrate, recovered alcohol is concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with concentration and recovery ethyl alcohol The pure water dilution of remaining extracting solution same volume successively uses deionized water and 50% by D101 large pore resin absorption column afterwards Edible alcohol elution, collect and merge eluent after corresponding eluent, centrifugation removal insoluble matter, vacuum decompression under the conditions of 60 DEG C It is concentrated into the clear cream of relative density about 1.18, obtains leaves of Hawthorn composite vegetables extractive, it is spare;
Step 2) takes out leaves of Hawthorn composite vegetables extractive obtained in step 1) according to following mass percent respectively, And glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, d- alpha-tocopherol, hyaluronic acid, methylparaben and Deionized water, it is spare;Wherein, leaves of Hawthorn composite vegetables extractive 14%, glycerol 4%, propylene glycol 4.5%, gamma-polyglutamic acid 3%, trehalose 2%, triethanolamine 0.5%, d- alpha-tocopherol 0.6%, hyaluronic acid 0.085%, methylparaben 0.085%, deionized water 71.23%;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), is sequentially added Deionized water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Close object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 Homogeneous is uniformly mixed under the conditions of DEG C, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains A group raw mixture by step 5) Interior, homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under room temperature.
The skin care item are manufactured using the technique, can ensure that the quality and effect of skin care item, and non-stimulated to skin.It adopts The skin care item being prepared in aforementioned manners can be used in preparing face cream or skin care hair gel cream.
Embodiment 8, a kind of skin care item containing hawthorne leaf P.E, including each component measured by mass percentage: mountain Short, bristly hair or beard leaf composite vegetables extractive 13%, glycerol 5%, propylene glycol 4%, gamma-polyglutamic acid 3%, trehalose 3%, triethanolamine 0.5%, d- alpha-tocopherol 0.2%, hyaluronic acid 0.08%, methylparaben 0.08%, deionized water 71.14%;Wherein, mountain Short, bristly hair or beard leaf composite vegetables extractive is each component measured according to following mass percent, extracted, be prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;
Using above-mentioned formula a kind of skin care item containing hawthorne leaf P.E specific the preparation method is as follows:
Step 1), the leaves of Hawthorn for taking out corrresponding quality respectively according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, granatum, Peppermint, the root of Dahurain angelica, purslane, it is spare;Wherein, leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%;By leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane, add 50% (V/V) edible alcohol, 50% (V/V) edible alcohol quality being added is leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, granatum, thin Lotus, the root of Dahurain angelica, 8 times of purslane gross mass, extract 2 hours under the conditions of 64 DEG C, collect filtrate, same batten after being filtered to remove filter residue Part extracts twice altogether, merging filtrate, recovered alcohol is concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with concentration and recovery ethyl alcohol The pure water dilution of remaining extracting solution same volume successively uses deionized water and 50% by D101 large pore resin absorption column afterwards Edible alcohol elution, collect and merge eluent after corresponding eluent, centrifugation removal insoluble matter, vacuum decompression under the conditions of 60 DEG C It is concentrated into the clear cream of relative density about 1.16, obtains leaves of Hawthorn composite vegetables extractive, it is spare;
Step 2) takes out leaves of Hawthorn composite vegetables extractive obtained in step 1) according to following mass percent respectively, And glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, d- alpha-tocopherol, hyaluronic acid, methylparaben and Deionized water, it is spare;Wherein, leaves of Hawthorn composite vegetables extractive 13%, glycerol 5%, propylene glycol 4%, gamma-polyglutamic acid 3%, Trehalose 3%, triethanolamine 0.5%, d- alpha-tocopherol 0.2%, hyaluronic acid 0.08%, methylparaben 0.08%, go from Sub- water 71.14%;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), is sequentially added Deionized water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Close object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 Homogeneous is uniformly mixed under the conditions of DEG C, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains A group raw mixture by step 5) Interior, homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under room temperature.
The skin care item are manufactured using the technique, can ensure that the quality and effect of skin care item, and non-stimulated to skin.It adopts The skin care item being prepared in aforementioned manners can be used in preparing face cream or skin care hair gel cream.

Claims (6)

1. a kind of skin care item containing hawthorne leaf P.E, which is characterized in that including each group measured by mass percentage as follows Point: leaves of Hawthorn composite vegetables extractive 10~15%, glycerol 3~6%, propylene glycol 3~5%, gamma-polyglutamic acid 3~5%, sea Algae sugar 2~5%, triethanolamine 0.5~1.0%, d- alpha-tocopherol 0.2~0.8%, hyaluronic acid 0.05~0.1%, nipalgin Methyl esters 0.05~0.1%, deionized water adds to 100%;
The leaves of Hawthorn composite vegetables extractive is the leaves of Hawthorn measured according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, pomegranate Skin, peppermint, the root of Dahurain angelica, purslane various plants, extracted, the leaves of Hawthorn composite extract that is prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%.
2. a kind of skin care item containing hawthorne leaf P.E, which is characterized in that including each group measured by mass percentage as follows Point: leaves of Hawthorn composite vegetables extractive 11~14%, glycerol 4~5%, propylene glycol 3.5~4.5%, gamma-polyglutamic acid 3.5~ 4.5%, trehalose 3~4%, triethanolamine 0.65~0.85%, d- alpha-tocopherol 0.4~0.6%, hyaluronic acid 0.065~ 0.05%, methylparaben 0.065~0.085%, deionized water add to 100%;
The leaves of Hawthorn composite vegetables extractive is the leaves of Hawthorn measured according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, pomegranate Skin, peppermint, the root of Dahurain angelica, purslane various plants, the extracted, compound extract that is prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, Ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%.
3. a kind of skin care item containing hawthorne leaf P.E, which is characterized in that including each group measured by mass percentage as follows Point: leaves of Hawthorn composite vegetables extractive 12.5%, glycerol 4.5%, propylene glycol 4%, gamma-polyglutamic acid 4%, trehalose 3.5%, Triethanolamine 0.75%, d- alpha-tocopherol 0.5%, hyaluronic acid 0.075%, methylparaben 0.075%, deionized water adds to 100%;
The leaves of Hawthorn composite vegetables extractive is the leaves of Hawthorn measured according to following mass percent, Radix Glycyrrhizae, ginkgo leaf, pomegranate Skin, peppermint, the root of Dahurain angelica, purslane various plants, the extracted, compound extract that is prepared: leaves of Hawthorn 20%, Radix Glycyrrhizae 17%, Ginkgo leaf 16%, granatum 16%, peppermint 12%, the root of Dahurain angelica 10%, purslane 9%.
4. a kind of preparation method of the skin care item containing hawthorne leaf P.E, which is characterized in that preparation method is as follows:
Step 1) is measured according to the mass percent of each component described in the claims, takes out leaves of Hawthorn, Radix Glycyrrhizae, silver Apricot leaf, granatum, peppermint, the root of Dahurain angelica, purslane extract to obtain leaves of Hawthorn composite vegetables extractive by ethyl alcohol, spare;
Step 2) is measured according to the mass percent of each component described in the claims, is taken out obtained in step 1) Leaves of Hawthorn composite vegetables extractive and glycerol, propylene glycol, gamma-polyglutamic acid, trehalose, triethanolamine, d- alpha-tocopherol, Hyaluronic acid, methylparaben and deionized water, it is spare;
The leaves of Hawthorn composite vegetables extractive taken out in step 2) is put into sterile equalizer by step 3), sequentially add from Sub- water, gamma-polyglutamic acid, trehalose, glycerol and propylene glycol, homogeneous is uniformly mixed under the conditions of 45 DEG C, is obtained A group raw material and is mixed Object;
Step 4), triethanolamine, d- alpha-tocopherol, hyaluronic acid and the methylparaben that will be taken out in step 2), 4~10 DEG C of items Homogeneous is uniformly mixed under part, obtains B group raw mixture;
B group raw mixture obtained in step 4) is added in step 3) and obtains in A group raw mixture by step 5), room Homogeneous is uniformly mixed to get the skin care item containing hawthorne leaf P.E are arrived under the conditions of temperature.
5. a kind of preparation method of skin care item containing hawthorne leaf P.E according to claim 4, it is characterised in that:
Leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane are extracted by ethyl alcohol in the step 1), obtain mountain The method of short, bristly hair or beard leaf composite vegetables extractive are as follows: take leaves of Hawthorn, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, purslane, be added Edible alcohol extracts twice, and used edible alcohol is the edible alcohol that volume ratio is 50% every time, described used every time To edible alcohol quality be leaves of Hawthorn used, Radix Glycyrrhizae, ginkgo leaf, granatum, peppermint, the root of Dahurain angelica, 8 times of purslane gross mass, Extracting every time is extracted 2 hours under the conditions of 55~65 DEG C, collects filtrate after being filtered to remove filter residue, the filtrate that will be extracted twice Merge, recovered alcohol is concentrated under reduced pressure under the conditions of 60 DEG C to filtrate without alcohol taste, with identical with extracting solution remaining after concentration and recovery ethyl alcohol The pure water of volume dilutes, by D101 large pore resin absorption column, the edible wine for being successively 50% with deionized water and volume ratio Fine purifiation is de-, collects and merges eluent after corresponding eluent, centrifugation removal insoluble matter, and vacuum-concentrcted is to phase under the conditions of 60 DEG C To the clear cream of density about 1.15~1.20 to get leaves of Hawthorn composite vegetables extractive.
6. according to a kind of application for skin care item containing hawthorne leaf P.E that claim 4 obtains, it is characterised in that: the shield Skin product are preparing the application in face cream or skin care hair gel cream.
CN201710451390.8A 2017-06-15 2017-06-15 A kind of skin care item and the preparation method and application thereof containing hawthorne leaf P.E Pending CN109125150A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110433114A (en) * 2019-08-16 2019-11-12 湖南科技学院 The plant extracts inhibited tyrosinase activity and its application
CN113041182A (en) * 2019-12-27 2021-06-29 广州市科能化妆品科研有限公司 Collagenase inhibitor, anti-aging skin lightening lotion containing collagenase inhibitor and preparation method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110433114A (en) * 2019-08-16 2019-11-12 湖南科技学院 The plant extracts inhibited tyrosinase activity and its application
CN110433114B (en) * 2019-08-16 2022-03-22 湖南科技学院 Plant extract for inhibiting tyrosinase activity and application thereof
CN113041182A (en) * 2019-12-27 2021-06-29 广州市科能化妆品科研有限公司 Collagenase inhibitor, anti-aging skin lightening lotion containing collagenase inhibitor and preparation method

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