CN109116033A - 用于选择抗细胞凋亡信号传导细胞的装置和方法及其用途 - Google Patents

用于选择抗细胞凋亡信号传导细胞的装置和方法及其用途 Download PDF

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Publication number
CN109116033A
CN109116033A CN201810972287.2A CN201810972287A CN109116033A CN 109116033 A CN109116033 A CN 109116033A CN 201810972287 A CN201810972287 A CN 201810972287A CN 109116033 A CN109116033 A CN 109116033A
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cell
cells
apoptosis
fasl
another embodiment
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Chinese (zh)
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S·亚科尼
N·阿斯肯纳西
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Quoin Pharmaceuticals Ltd
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Cellect Biotechnology Ltd
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/51Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/25Tumour necrosing factors [TNF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/599Cell markers; Cell surface determinants with CD designations not provided for elsewhere

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • General Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
CN201810972287.2A 2012-03-06 2013-03-05 用于选择抗细胞凋亡信号传导细胞的装置和方法及其用途 Pending CN109116033A (zh)

Applications Claiming Priority (3)

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US201261607033P 2012-03-06 2012-03-06
US61/607,033 2012-03-06
CN201380021092.5A CN104245924B (zh) 2012-03-06 2013-03-05 用于选择抗细胞凋亡信号传导细胞的装置和方法及其用途

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CN201380021092.5A Expired - Fee Related CN104245924B (zh) 2012-03-06 2013-03-05 用于选择抗细胞凋亡信号传导细胞的装置和方法及其用途

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US (2) US9783778B2 (https=)
EP (2) EP2823040B1 (https=)
JP (1) JP6429191B2 (https=)
KR (1) KR101912982B1 (https=)
CN (2) CN109116033A (https=)
AU (1) AU2013229008B2 (https=)
CA (1) CA2866358C (https=)
DK (1) DK2823040T3 (https=)
IL (1) IL234459B (https=)
RU (1) RU2630301C2 (https=)
WO (1) WO2013132477A1 (https=)

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EP3054961B1 (en) * 2013-10-09 2020-08-26 Cellect Biotherapeutics Ltd. Activation of hematopoietic progenitors by pretransplant exposure to death ligands
WO2016193986A2 (en) 2015-06-05 2016-12-08 Cellect Biotherapeutics Ltd. Selective surfaces for, and methods of, selecting a population of stem and progenitor cells, and uses thereof
EP3841196A4 (en) * 2018-08-22 2022-09-21 Cellect Biotherapeutics Ltd. MODULATION OF CELLS RESPONSIVE TO APOPTOSIS
US20220002363A1 (en) * 2020-07-03 2022-01-06 United States Government As Represented By The Department Of Veterans Affairs Compositions and methods for treating pulmonary disease

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Also Published As

Publication number Publication date
AU2013229008B2 (en) 2018-11-08
CA2866358A1 (en) 2013-09-12
EP3486315A1 (en) 2019-05-22
US9783778B2 (en) 2017-10-10
US20150044182A1 (en) 2015-02-12
JP6429191B2 (ja) 2018-11-28
EP2823040B1 (en) 2018-08-01
RU2014138001A (ru) 2016-04-20
WO2013132477A1 (en) 2013-09-12
JP2015510758A (ja) 2015-04-13
RU2630301C2 (ru) 2017-09-06
IL234459B (en) 2020-02-27
KR20150011796A (ko) 2015-02-02
EP2823040A1 (en) 2015-01-14
CN104245924A (zh) 2014-12-24
CA2866358C (en) 2020-06-23
KR101912982B1 (ko) 2018-10-29
US20180208888A1 (en) 2018-07-26
EP2823040A4 (en) 2016-01-06
AU2013229008A1 (en) 2014-09-18
CN104245924B (zh) 2020-05-01
DK2823040T3 (en) 2018-11-19

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