CN109100189A - A kind of cell tissue sample pelletizer - Google Patents

A kind of cell tissue sample pelletizer Download PDF

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Publication number
CN109100189A
CN109100189A CN201810749044.2A CN201810749044A CN109100189A CN 109100189 A CN109100189 A CN 109100189A CN 201810749044 A CN201810749044 A CN 201810749044A CN 109100189 A CN109100189 A CN 109100189A
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motion bar
film
tissue sample
seat
cell tissue
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CN201810749044.2A
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CN109100189B (en
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焦明远
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/34Microscope slides, e.g. mounting specimens on microscope slides

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention proposes a kind of cell tissue sample pelletizer, including loading seat, objective table, film-making seat and film-making platform, the first strip-shaped hole and right angle fixed plate are provided on objective table, first motion bar, lead screw and first motor there are two being symmetrical arranged under objective table, archimedean spiral groove is provided on film-making platform, the second motion bar is provided in the archimedean spiral groove, the second motion bar is connected with the second motor, hollow cylinder cam third motion bar and tup in turn.The present invention clamps glass slide and coverslip using first motor driving right angle fixed plate, linear reciprocating motion, which is done, using the second motor driven third motion bar beats passage bubble, and spotlight makes operator more meticulously observe the bubble retained in sample, by being respectively completed the work for clamping glass slide and coverslip and the work for excluding bubble by motor machine, it reduces workload and obtained sample quality is higher, and the present invention has rational design, structure is simple, is suitble to large-scale promotion.

Description

A kind of cell tissue sample pelletizer
Technical field
The invention belongs to middle school student's technical field of experiment equipment more particularly to a kind of cell tissue sample pelletizers.
Background technique
High school biology requires student that must learn using microscope and the method for grasping basic production sample, especially It is to need to recognize some eucaryotic cell structures by film-making sample, Junior is main when student just contacts biology It is simple plant specimen, the production of zooblast tissue samples, senior high school period is mainly microorganism sample and cell culture, and And the culture of microorganism is all especially important for many important experiments.Film-making is the of most of observation experiments and test experience One step, the effect of the relationship between quality of film-making to observation and detection.
Currently, needing to be smeared with particular solution, then by coverslip lid after many cell tissue samples are placed on glass slide To the top of glass slide, on coverslip lid to glass slide after need to be inhaled the moisture between coverslip and glass slide with blotting paper It walks, while a certain number of bubbles can be generated between coverslip and glass slide, producers is needed constantly to be beaten either with hand hammer With hard device along the upper surface of coverslip, the bubble around cell sample is gradually discharged, to improve in microscopy process The middle rate for finding target cell, while avoiding the effect of exclusion interference observation of the bubble accumulation to coloring agent;And manpower Stability when in conjunction with coverslip and glass slide is poor, and the bubble of generation is more, influences the quality of film-making to a certain extent;Again Person, the workload that bubble is vented in a certain number of sample processes of film-making is quite big, and middle school student do the time tested and experiment Room is all very limited, will delay teachers' instruction progress, the enthusiasm of student significantly if the efficiency of film-making cannot be improved Also it can be gradually reduced.
Summary of the invention
Present in the present invention is directed in terms of the above-mentioned bubble excluded between glass slide and coverslip during sample film-making The technical issues of, propose that a kind of design is reasonable, structure is simple, efficiently a kind of cell tissue sample film-making dress of easy to use and film-making It sets.
In order to achieve the above object, the technical solution adopted by the present invention is a kind of cell tissue sample provided by the invention Pelletizer, including loading seat and film-making seat are provided with supporting table on the loading seat, are provided with loading in the supporting table Platform, there are four the first strip-shaped hole and four right angle fixed plates, the lower surfaces of the objective table for the upper surface setting of the objective table It is symmetrical arranged there are two the first motion bar, there are two the second strip-shaped hole, the right angle fixed plates for setting on first motion bar On be provided with the bolt through the first strip-shaped hole and the second strip-shaped hole, the two sides of the supporting table are provided with bearing block, the axis Seat is held to connect with lead screw, the lead screw passes through the first motion bar and connect with first motor, and the loading seat is arranged on film-making seat, It is provided with film-making platform on the film-making seat, archimedean spiral groove, the archimedean spiral groove are provided on the film-making platform In be provided with the second motion bar, the bottom of second motion bar is provided with the second motor, and the output end of second motor is set It is equipped with hollow cylinder cam, the hollow cylinder cam is internally provided with third motion bar, the bottom of the third motion bar It is provided with tup.
Preferably, being provided with connecting cylinder on second motor, the hollow cylinder cam is arranged in connecting cylinder, institute The outer wall for stating connecting cylinder is provided with active ring, and the active ring is connect with c-type frame, the c-type frame and the fixed company of third motion bar It connects.
Preferably, being provided with sliding top guide at the top of the third motion bar, the inner wall of the hollow cylinder cam is set It is equipped with the track groove mobile for sliding top guide.
Preferably, the center of the objective table is provided with convergent hole, plate glass is provided at the convergent hole, it is described Supporting table is internally provided with spotlight corresponding with optically focused hole site.
Preferably, first strip-shaped hole radially distributes along the center of convergent hole.
Preferably, the first motor is arranged in first motor case, loading seat is arranged in the first motor case Side.
Preferably, the side of the right angle fixed plate is provided with gas vent, the inner wall of the side of the right angle fixed plate It is provided with trough with straight angle.
Preferably, the film-making seat is gooseneck type seat, the loading for placing loading seat is provided on the film-making seat Slot.
Preferably, being provided with handle at the top of second motion bar.
Compared with prior art, the advantages and positive effects of the present invention are,
1, a kind of cell tissue sample pelletizer provided by the invention keeps the first motion bar mobile using the rotation of lead screw And drive the two right angle fixed plates ipsilateral with it along the first strip-shaped hole close to or far from the center of objective table, to will carry Glass slide and coverslip on object platform clamp or loosen, and the sample that opening simultaneously spotlight can illuminate on glass slide makes operator More meticulously observe the bubble retained in sample;Cylindrical cam rotation is driven to do third motion bar back and forth using the second motor Linear motion, to realize the purpose beaing bubble and moving it;It can make the second motor, cylindrical cam by rotational handle And third motion bar is rotated along archimedean spiral groove, is pushed out glass slide and coverslip so that bubble gradually be beaten Edge.The present invention completes to exclude the work of bubble by mechanical, reduces labor workload and the bubble in obtained sample Quantity is greatly lowered, and has saved the time of student experimenting and observing effect is splendid, meanwhile, the present invention has rational design, structure letter It is single, it is suitble to large-scale promotion.
Detailed description of the invention
In order to illustrate the technical solution of the embodiments of the present invention more clearly, required use in being described below to embodiment Attached drawing be briefly described, it should be apparent that, drawings in the following description are some embodiments of the invention, for ability For the those of ordinary skill of domain, without any creative labor, it can also be obtained according to these attached drawings others Attached drawing.
Fig. 1 is a kind of cross-sectional view for cell tissue sample pelletizer that embodiment provides;
Fig. 2 is a kind of side view for cell tissue sample pelletizer that embodiment provides;
Fig. 3 is a kind of top view for cell tissue sample pelletizer that embodiment provides;
Fig. 4 is the bottom view for the objective table that embodiment provides;
Fig. 5 is a kind of axonometric drawing of the overall mechanism for cell tissue sample pelletizer that embodiment provides;
In above each figure, 1, loading seat;2, supporting table;3, objective table;31, the first strip-shaped hole;4, right angle fixed plate;41, Trough with straight angle;42, gas vent;5, the first motion bar;51, the second strip-shaped hole;6, bolt;7, bearing block;8, lead screw;9, the first electricity Machine;10, first motor case;11, film-making seat;111, loading slot;12, film-making platform;121, archimedean spiral groove;13, second is living Lever;14, the second motor;15, hollow cylinder cam;16, third motion bar;17, tup;18, connecting cylinder;19, active ring; 20, c-type frame;21, handle;22, convergent hole;23, spotlight.
Specific embodiment
To better understand the objects, features and advantages of the present invention, with reference to the accompanying drawings and examples The present invention will be further described.It should be noted that in the absence of conflict, in embodiments herein and embodiment Feature can be combined with each other.For sake of convenience, hereafter such as there are "upper", "lower", "left", "right" printed words, only indicate and attached drawing sheet The upper and lower, left and right direction of body is consistent, does not play restriction effect to structure.
In the following description, numerous specific details are set forth in order to facilitate a full understanding of the present invention, still, the present invention may be used also To be implemented using other modes described herein are different from, therefore, the present invention is not limited to the specific of specification is described below The limitation of embodiment.
Embodiment (does not wherein draw archimedean spiral groove in figure) as shown in Figure 1, Figure 2, shown in Fig. 3, Fig. 4 and Fig. 5, the present invention A kind of cell tissue sample pelletizer provided includes mainly three parts, and first part is mainly by objective table 3 and loading The station for being used to place glass slide and coverslip that seat 1 is constituted, second part is mainly by the second motion bar 13, the second motor 14, the mechanical mechanism for being used to beat passage bubble that hollow cylinder cam 15, third motion bar 16 and tup 17 form;Third portion Divide the transition mechanism for being used to combine first part and second part being made of film-making platform 12 and film-making seat 11.
Specifically, a kind of cell tissue sample pelletizer provided by the invention, first part include loading seat 1, institute It states and is provided with supporting table 2 on loading seat 1, objective table 3 is provided in the supporting table 2, the upper surface of the objective table 3 is provided with Four the first strip-shaped holes 31 and four right angle fixed plates 4, first strip-shaped hole 31 is along radial point of the center of convergent hole 22 Cloth, the lower surface of the objective table 3 are symmetrical arranged there are two the first motion bar 5, and there are two for setting on first motion bar 5 Two strip-shaped holes 51 are provided with the bolt 6 through the first strip-shaped hole 31 and the second strip-shaped hole 51 in the right angle fixed plate 4, described The two sides of supporting table 2 are provided with bearing block 7, and the bearing block 7 is connect with lead screw 8, the lead screw 8 pass through the first motion bar 5 with First motor 9 connects, and the first motor 9 is arranged in first motor case 10, and the first motor case 10 is arranged in loading seat Side, that is, there are two first motor case, the side of the right angle fixed plate 4 is provided with gas vent 42, and the right angle is solid The inner wall of the side of fixed board 4 is provided with trough with straight angle 41.
The working principle of first part of the present invention, the starting of first motor 9 drives lead screw 8 to rotate, while lead screw 8 drives first Motion bar 5, which does horizontal translocation, makes right angle fixed plate 4 along the first strip-shaped hole 31 close to the center of objective table 3, until trough with straight angle 41 Glass slide and coverslip are pushed down simultaneously, and the gas vent 42 in right angle fixed plate 4 can prevent bubble to be pushed to load glass It is agglomerated when the edge of piece and coverslip, is conducive to gas and is discharged from its edge;It can be 8 turns of lead screw that bearing is arranged in bearing block 7 It is dynamic that fulcrum is provided, and 8 rotation friction of lead screw reduces, it should be noted that the switch of first motor 9 belongs to spring type contact Switch facilitates realization to open and stops, and regulation is convenient, will not sample chips be crushed or be squeezed broken.
In order to realize that machinery beats discharge bubble, second part and Part III provided by the invention can be successfully complete At.Specifically, the film-making seat 11 is gooseneck type seat, and the loading slot for placing loading seat 1 is provided on the film-making seat 11 111, the film-making platform 12 is arranged in the gooseneck boom end of film-making seat 11 and is provided with archimedean spiral groove on film-making platform 12 121, the second motion bar 13 is provided in the archimedean spiral groove 121, and the bottom of second motion bar 13 is provided with Two motors 14, the output end of second motor 14 are provided with hollow cylinder cam 15, the inside of the hollow cylinder cam 15 It is provided with third motion bar 16, the top of the third motion bar 16 is provided with sliding top guide, the hollow cylinder cam 15 Inner wall is provided with the track groove mobile for sliding top guide, and the bottom of the third motion bar 16 is provided with tup 17.Described second Connecting cylinder 18 is provided on motor 14, the hollow cylinder cam 15, which is arranged in connecting cylinder 18 to form itself, centainly to be protected, The outer wall of the connecting cylinder 18 is provided with active ring 19, and the active ring 19 is connect with c-type frame 20, the c-type frame 20 and third Motion bar 16 is fixedly connected, and the top of second motion bar 16 is provided with handle 21.
The inside that hollow cylinder cam 15 is arranged in third motion bar 16 in second part is to make third motion bar 16 move in a straight line along the axle center of hollow cylinder cam 15, in this case, the real-time position that handle 21 is adjusted in the rotation Set be exactly tup 17 center, if can deviate from the center of cylindrical cam according to the design of existing cylindrical cam, It is unfavorable for adjusting;Moreover, the effect of active ring 19 and c-type frame 20 is exactly to control third motion bar 16 not with hollow cylinder cam 15 It moves in a circle, guarantees that the motion profile of sliding top guide is exactly the track of track groove, and then guarantee effective straight reciprocating motion; For total function, second part and Part III are arranged in this way it is achieved that the mechanism of entire first part is consolidated It is scheduled in loading slot 111, avoids moving horizontally when tapping glass slide and coverslip;The process of work is the second electricity The starting of machine 14 can drive hollow cylinder cam 15 to rotate, and sliding top guide is moved along track groove, third motion bar 16 and tup 17 linear reciprocating motions, manual moving handle 21, handle 21 drive entire second part along archimedean spiral groove 121 be Ah Base Mead spiral motion.The position of bubble is first determined in exclusion bubble straight line, is preferably beaten since center of a sample, Er Qiechui First 17 diameter has to be larger than the groove width of archimedean spiral groove 121, otherwise will be between the slot because of archimedean spiral groove 121 Away from and occur to omit some bubbles.Herein, need to the maximum polar diameter of archimedean spiral groove 121 be set equal to or is greater than carry glass The length of piece, it is ensured that big branch's bubble is pushed when not being pushed to the left and right maximum distance of glass slide and coverslip The front and back side of glass slide out avoids bubble accumulation from causing to distribute the bubbles into glass slide and Gai Bo again at exclusion bubble work end Between piece, and more fully bubble first can be polymerize according to spiral of Archimedes movement and pushed out again.
In order to improve slice-making quality, the center of the objective table 3 provided by the invention is provided with convergent hole 22, the optically focused Plate glass is provided at hole 22 can support glass slide, and being internally provided with for the supporting table 2 is corresponding with 22 position of convergent hole Spotlight 23 can provide light source, and operator is made more meticulously to observe the bubble retained in sample, be until not observing bubble Only.
On the whole, the present invention completes to exclude the work of bubble by mechanical, reduces labor workload and obtains To sample in number of bubbles be greatly lowered, saved the time of student experimenting and observing effect be splendid, meanwhile, the present invention Design is reasonable, structure is simple, is suitble to large-scale promotion.
The above described is only a preferred embodiment of the present invention, being not that the invention has other forms of limitations, appoint What those skilled in the art changed or be modified as possibly also with the technology contents of the disclosure above equivalent variations etc. It imitates embodiment and is applied to other fields, but without departing from the technical solutions of the present invention, according to the technical essence of the invention Any simple modification, equivalent variations and remodeling to the above embodiments, still fall within the protection scope of technical solution of the present invention.

Claims (9)

1. a kind of cell tissue sample pelletizer, which is characterized in that including loading seat and film-making seat, be arranged on the loading seat There is supporting table, objective table is provided in the supporting table, there are four the first strip-shaped hole and four for the upper surface setting of the objective table A right angle fixed plate, the lower surface of the objective table are symmetrical arranged there are two the first motion bar, are arranged on first motion bar There are two the second strip-shaped hole, it is provided with the bolt through the first strip-shaped hole and the second strip-shaped hole in the right angle fixed plate, it is described The two sides of supporting table are provided with bearing block, and the bearing block is connect with lead screw, and the lead screw passes through the first motion bar and the first electricity Machine connection, the loading seat are arranged on film-making seat, and film-making platform is provided on the film-making seat, be provided on the film-making platform Ah Base Mead helicla flute is provided with the second motion bar in the archimedean spiral groove, and the bottom of second motion bar is provided with Second motor, the output end of second motor are provided with hollow cylinder cam, and the hollow cylinder cam is internally provided with The bottom of third motion bar, the third motion bar is provided with tup.
2. a kind of cell tissue sample pelletizer according to claim 1, which is characterized in that set on second motor It is equipped with connecting cylinder, the hollow cylinder cam is arranged in connecting cylinder, and the outer wall of the connecting cylinder is provided with active ring, the work Moving-coil is connect with c-type frame, and the c-type frame is fixedly connected with third motion bar.
3. a kind of cell tissue sample pelletizer according to claim 2, which is characterized in that the third motion bar Top is provided with sliding top guide, and the inner wall of the hollow cylinder cam is provided with the track groove mobile for sliding top guide.
4. a kind of cell tissue sample pelletizer according to claim 3, which is characterized in that the center of the objective table It is provided with convergent hole, plate glass is provided at the convergent hole, the supporting table is internally provided with and optically focused hole site pair The spotlight answered.
5. a kind of cell tissue sample pelletizer according to claim 4, which is characterized in that first strip-shaped hole edge The center of convergent hole radially distributes.
6. a kind of cell tissue sample pelletizer according to claim 5, which is characterized in that the first motor setting In first motor case, the side of loading seat is arranged in the first motor case.
7. a kind of cell tissue sample pelletizer according to claim 6, which is characterized in that the right angle fixed plate Side is provided with gas vent, and the inner wall of the side of the right angle fixed plate is provided with trough with straight angle.
8. a kind of cell tissue sample pelletizer according to claim 7, which is characterized in that the film-making seat is gooseneck Formula seat is provided with the loading slot for placing loading seat on the film-making seat.
9. a kind of cell tissue sample pelletizer according to claim 8, which is characterized in that second motion bar Top is provided with handle.
CN201810749044.2A 2018-07-10 2018-07-10 Cell tissue sample film-making device Active CN109100189B (en)

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Application Number Priority Date Filing Date Title
CN201810749044.2A CN109100189B (en) 2018-07-10 2018-07-10 Cell tissue sample film-making device

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Application Number Priority Date Filing Date Title
CN201810749044.2A CN109100189B (en) 2018-07-10 2018-07-10 Cell tissue sample film-making device

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CN109100189A true CN109100189A (en) 2018-12-28
CN109100189B CN109100189B (en) 2020-12-04

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110673324A (en) * 2019-09-27 2020-01-10 佛山科学技术学院 Glass slide structure suitable for confocal microscope
CN111909831A (en) * 2020-08-07 2020-11-10 常州惠农生物科技有限公司 Solid state fermentation air removal device
CN112345738A (en) * 2020-10-26 2021-02-09 湖南中昊建设项目管理有限公司 Slump meter

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CN103868779A (en) * 2014-04-04 2014-06-18 黑龙江大学 Method for cutting beet ovule and producing sheet in transparent condition
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CN107219111A (en) * 2017-06-08 2017-09-29 黑龙江大学 A kind of chromosome flaking method of distant hybridization beet
CN206945405U (en) * 2017-06-30 2018-01-30 迈克医疗电子有限公司 Sample processing apparatus
CN207263509U (en) * 2017-09-28 2018-04-20 许昌学院 A kind of tissue specimen fixing device for pathologic finding

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EP0440223A2 (en) * 1990-01-31 1991-08-07 Ladislav Novotny Method of preparation of miniaturized sensors on basis of fluids and arrangement of the measuring system
CN103868779A (en) * 2014-04-04 2014-06-18 黑龙江大学 Method for cutting beet ovule and producing sheet in transparent condition
EP3222996A1 (en) * 2016-03-21 2017-09-27 Tintometer GmbH Calibration suspension unit, method for producing a calibration suspension unit and use of a calibration suspension unit
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CN112345738A (en) * 2020-10-26 2021-02-09 湖南中昊建设项目管理有限公司 Slump meter

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