CN109097434A - 一种唾液酸检测试剂盒 - Google Patents
一种唾液酸检测试剂盒 Download PDFInfo
- Publication number
- CN109097434A CN109097434A CN201810928656.8A CN201810928656A CN109097434A CN 109097434 A CN109097434 A CN 109097434A CN 201810928656 A CN201810928656 A CN 201810928656A CN 109097434 A CN109097434 A CN 109097434A
- Authority
- CN
- China
- Prior art keywords
- reagent
- sialic acid
- kit
- testing agent
- edta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 title claims abstract description 35
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 title claims abstract description 34
- 238000012360 testing method Methods 0.000 title abstract description 27
- 239000003795 chemical substances by application Substances 0.000 title abstract description 15
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 42
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims abstract description 16
- 238000004458 analytical method Methods 0.000 claims abstract description 9
- 230000035945 sensitivity Effects 0.000 claims abstract description 9
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229910001629 magnesium chloride Inorganic materials 0.000 claims abstract description 8
- 108010024636 Glutathione Proteins 0.000 claims abstract description 7
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims abstract description 7
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 claims description 10
- 102000005348 Neuraminidase Human genes 0.000 claims description 9
- 108010006232 Neuraminidase Proteins 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 claims description 7
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 claims description 7
- 101710088194 Dehydrogenase Proteins 0.000 claims description 6
- 102000001390 Fructose-Bisphosphate Aldolase Human genes 0.000 claims description 5
- 108010068561 Fructose-Bisphosphate Aldolase Proteins 0.000 claims description 5
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 claims description 5
- 229950006238 nadide Drugs 0.000 claims description 5
- 210000005036 nerve Anatomy 0.000 claims description 5
- 238000005259 measurement Methods 0.000 claims description 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 12
- 238000001514 detection method Methods 0.000 abstract description 9
- 230000000052 comparative effect Effects 0.000 description 14
- 238000002835 absorbance Methods 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 7
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 4
- CERZMXAJYMMUDR-UHFFFAOYSA-N neuraminic acid Natural products NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO CERZMXAJYMMUDR-UHFFFAOYSA-N 0.000 description 4
- 239000002253 acid Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- BQINXKOTJQCISL-GRCPKETISA-N keto-neuraminic acid Chemical compound OC(=O)C(=O)C[C@H](O)[C@@H](N)[C@@H](O)[C@H](O)[C@H](O)CO BQINXKOTJQCISL-GRCPKETISA-N 0.000 description 3
- 239000002504 physiological saline solution Substances 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000012202 endocytosis Effects 0.000 description 2
- 238000009533 lab test Methods 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000009972 noncorrosive effect Effects 0.000 description 2
- 229940107700 pyruvic acid Drugs 0.000 description 2
- -1 saccharide compound Chemical class 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 238000010200 validation analysis Methods 0.000 description 2
- UHDGCWIWMRVCDJ-UHFFFAOYSA-N 1-beta-D-Xylofuranosyl-NH-Cytosine Natural products O=C1N=C(N)C=CN1C1C(O)C(O)C(CO)O1 UHDGCWIWMRVCDJ-UHFFFAOYSA-N 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- UHDGCWIWMRVCDJ-PSQAKQOGSA-N Cytidine Natural products O=C1N=C(N)C=CN1[C@@H]1[C@@H](O)[C@@H](O)[C@H](CO)O1 UHDGCWIWMRVCDJ-PSQAKQOGSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 102000004895 Lipoproteins Human genes 0.000 description 1
- 108090001030 Lipoproteins Proteins 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 229920000057 Mannan Polymers 0.000 description 1
- SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 description 1
- 102000048245 N-acetylneuraminate lyases Human genes 0.000 description 1
- 108700023220 N-acetylneuraminate lyases Proteins 0.000 description 1
- SQVRNKJHWKZAKO-LUWBGTNYSA-N N-acetylneuraminic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)CC(O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-LUWBGTNYSA-N 0.000 description 1
- BAWFJGJZGIEFAR-NNYOXOHSSA-O NAD(+) Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-O 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 238000000184 acid digestion Methods 0.000 description 1
- 239000012445 acidic reagent Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 235000015278 beef Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000008133 cognitive development Effects 0.000 description 1
- 235000020247 cow milk Nutrition 0.000 description 1
- UHDGCWIWMRVCDJ-ZAKLUEHWSA-N cytidine Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O1 UHDGCWIWMRVCDJ-ZAKLUEHWSA-N 0.000 description 1
- IERHLVCPSMICTF-XVFCMESISA-N cytidine 5'-monophosphate Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O1 IERHLVCPSMICTF-XVFCMESISA-N 0.000 description 1
- IERHLVCPSMICTF-UHFFFAOYSA-N cytidine monophosphate Natural products O=C1N=C(N)C=CN1C1C(O)C(O)C(COP(O)(O)=O)O1 IERHLVCPSMICTF-UHFFFAOYSA-N 0.000 description 1
- 210000000172 cytosol Anatomy 0.000 description 1
- 125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000000630 fibrocyte Anatomy 0.000 description 1
- 230000004153 glucose metabolism Effects 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 235000020256 human milk Nutrition 0.000 description 1
- 210000004251 human milk Anatomy 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 210000003712 lysosome Anatomy 0.000 description 1
- 230000001868 lysosomic effect Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000008884 pinocytosis Effects 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 235000015277 pork Nutrition 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000012418 validation experiment Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810928656.8A CN109097434B (zh) | 2018-08-15 | 2018-08-15 | 一种唾液酸检测试剂盒 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810928656.8A CN109097434B (zh) | 2018-08-15 | 2018-08-15 | 一种唾液酸检测试剂盒 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN109097434A true CN109097434A (zh) | 2018-12-28 |
CN109097434B CN109097434B (zh) | 2021-08-27 |
Family
ID=64849883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810928656.8A Active CN109097434B (zh) | 2018-08-15 | 2018-08-15 | 一种唾液酸检测试剂盒 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109097434B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111334557A (zh) * | 2020-03-20 | 2020-06-26 | 中拓生物有限公司 | 一种稳定、抗干扰能力强的血清唾液酸测定试剂盒及其制备方法和应用 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63160600A (ja) * | 1986-12-24 | 1988-07-04 | Fujirebio Inc | ピルビン酸定量用試薬 |
CN101469344A (zh) * | 2007-12-29 | 2009-07-01 | 上海铂锦诊断用品有限公司 | 一种稳定的酶法测定唾液酸液体双试剂及其应用 |
CN102072953A (zh) * | 2010-12-30 | 2011-05-25 | 北京九强生物技术有限公司 | 一种稳定的酶法检测唾液酸的方法及试剂盒 |
CN102399851A (zh) * | 2011-10-25 | 2012-04-04 | 宁波美康生物科技有限公司 | 酶法唾液酸检测试剂盒 |
CN106092942A (zh) * | 2016-05-26 | 2016-11-09 | 安徽伊普诺康生物技术股份有限公司 | 一种测定唾液酸的试剂盒及其制备方法 |
CN106324234A (zh) * | 2016-08-08 | 2017-01-11 | 上海睿康生物科技有限公司 | 修饰的n‑乙酰神经氨酸醛缩酶及其制备方法和应用 |
-
2018
- 2018-08-15 CN CN201810928656.8A patent/CN109097434B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63160600A (ja) * | 1986-12-24 | 1988-07-04 | Fujirebio Inc | ピルビン酸定量用試薬 |
CN101469344A (zh) * | 2007-12-29 | 2009-07-01 | 上海铂锦诊断用品有限公司 | 一种稳定的酶法测定唾液酸液体双试剂及其应用 |
CN102072953A (zh) * | 2010-12-30 | 2011-05-25 | 北京九强生物技术有限公司 | 一种稳定的酶法检测唾液酸的方法及试剂盒 |
CN102399851A (zh) * | 2011-10-25 | 2012-04-04 | 宁波美康生物科技有限公司 | 酶法唾液酸检测试剂盒 |
CN106092942A (zh) * | 2016-05-26 | 2016-11-09 | 安徽伊普诺康生物技术股份有限公司 | 一种测定唾液酸的试剂盒及其制备方法 |
CN106324234A (zh) * | 2016-08-08 | 2017-01-11 | 上海睿康生物科技有限公司 | 修饰的n‑乙酰神经氨酸醛缩酶及其制备方法和应用 |
Non-Patent Citations (1)
Title |
---|
SELMA SÜER GÖKMEN 等: "Serum total and lipid-bound sialic acid levels following acute myocardial infarction", 《CLINICAL CHEMISTRY AND LABORATORY MEDICINE》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111334557A (zh) * | 2020-03-20 | 2020-06-26 | 中拓生物有限公司 | 一种稳定、抗干扰能力强的血清唾液酸测定试剂盒及其制备方法和应用 |
CN111334557B (zh) * | 2020-03-20 | 2020-11-06 | 中拓生物有限公司 | 一种稳定、抗干扰能力强的血清唾液酸测定试剂盒及其制备方法和应用 |
Also Published As
Publication number | Publication date |
---|---|
CN109097434B (zh) | 2021-08-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Black et al. | Determination of bilirubin UDP-glucuronyl transferase activity in needle-biopsy specimens of human liver | |
Weinbach et al. | Entamoeba histolytica: I. Aerobic metabolism | |
Watanabe et al. | Determination of hypoxanthine in fish meat with an enzyme sensor | |
CN101503732B (zh) | 一种葡萄糖氧化酶单一液体测定试剂 | |
CN109239059A (zh) | 一种糖化血清蛋白测定试剂盒及其制备方法和应用 | |
CN106399457B (zh) | 基于纳米模拟酶的可视化快速检测生物酶、蛋白质及其抑制剂的方法 | |
CN111304283A (zh) | 一种基于循环酶速率法测定hcy的试剂盒及其制备使用方法 | |
CN116804630B (zh) | 一种血清同型半胱氨酸测定试剂盒 | |
Wanders et al. | 3-Hydroxy-3-methylglutaryl-CoA lyase in human skin fibroblasts: study of its properties and deficient activity in 3-hydroxy-3-methylglutaric aciduria patients using a simple spectrophotometric method | |
CN109097434A (zh) | 一种唾液酸检测试剂盒 | |
US5525481A (en) | Enzymatic Reagents for ethanol assay containing diamino compounds | |
WO1993012254A1 (en) | Highly sensitive determination of d-3-hydroxybutyric acid or acetoacetic acid and composition therefor | |
Engelmann et al. | Age-related changes in ploidy levels and biochemical parameters in cardiac myocytes isolated from spontaneously hypertensive rats. | |
CN112255219A (zh) | 一种1,5-脱水山梨醇的测定试剂盒及其制备方法和应用 | |
Fujimura et al. | Microdetermination of galactose and galactose 1-phosphate in dried blood spots | |
CN105334203A (zh) | 一种检测生物素酶酶活性的试剂盒 | |
CN109298190A (zh) | 一种高密度脂蛋白胆固醇检测试剂盒 | |
Stephens et al. | Oxidative phosphorylation in smooth muscle | |
CN105510583A (zh) | 检测生物素酶酶活性的试剂盒 | |
CN105372218A (zh) | 生物素酶酶活性的检测方法 | |
Jabs et al. | Adenosine, inosine, and hypoxanthine/xanthine measured in tissue and plasma by a luminescence method | |
Sokol et al. | Mitochondrial hepatopathies | |
CN105372219A (zh) | 一种生物素酶酶活性的检测方法 | |
Iossa et al. | Effect of thyroid state and cold exposure on rat liver mitochondrial protein mass and function | |
CN109957603A (zh) | 一种乳酸检测试剂盒 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Sialic acid detection kit Effective date of registration: 20230628 Granted publication date: 20210827 Pledgee: Bank of Communications Ltd. Shandong branch Pledgor: BIOBASE BIODUSTRY (SHANDONG) Co.,Ltd. Registration number: Y2023980045843 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Granted publication date: 20210827 Pledgee: Bank of Communications Ltd. Shandong branch Pledgor: BIOBASE BIODUSTRY (SHANDONG) Co.,Ltd. Registration number: Y2023980045843 |