CN1090959C - Patent medicine contg. triditional Chinese medicine and western medicine for treating cough and asthma disease - Google Patents
Patent medicine contg. triditional Chinese medicine and western medicine for treating cough and asthma disease Download PDFInfo
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- CN1090959C CN1090959C CN99112280A CN99112280A CN1090959C CN 1090959 C CN1090959 C CN 1090959C CN 99112280 A CN99112280 A CN 99112280A CN 99112280 A CN99112280 A CN 99112280A CN 1090959 C CN1090959 C CN 1090959C
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Abstract
The present invention relates to a compound patent medicine prepared from traditional Chinese medicines and western medicines and used for treating cough and asthma, and a preparation method thereof, which belongs to the field of a compound patent medicine prepared from traditional Chinese medicines and western medicines and used for treating cough and asthma. The compound patent medicine comprises extractum liquiritiae powder, caladium powder, norfloxacin, aminophylline, prednisone, chlortrimeton, diazepam and clenbuterol. The compound patent medicine has the effects of diminishing inflammation, relieving asthma, alleviating cough, treating manifestation and root causes of trachitis, asthma, etc., and has the advantages of rapid effect taking, high therapeutic effects, high safety, broad application range and less side effect.
Description
The present invention relates to a kind of treat cough illness in, western compound recipe patent medicine and preparation method.
Cough illness means tracheitis, asthma, is a kind of common, frequently-occurring disease of respiratory system, has caused serious harm to human health.Along with atmospheric pollution, multiple composite factor such as environment change causes the rising that is in line of disease incidences such as tracheitis, asthma.According to investigations, China's prevalence is 3~5%, and about 4~6,000 ten thousand people are ill.Usually, people treat diseases such as tracheitis, asthma, and the Chinese medicine disease curing range is wide, can effect a permanent cure, and safety has no side effect, but it is slow to take effect.The Western medicine instant effect, but can only take stopgap measures, certain limitation of curing the disease, toxic and side effects is also more serious than disease itself sometimes to the harm that the patient brings, even is in peril of one's life.
Goal of the invention of the present invention is to provide a kind of Chinese and Western compound recipe patent medicine and preparation method for the treatment of cough illness.With this method make in, western compound recipe patent medicine, have the effect of antiinflammatory, Zhichuan, antitussive, for diseases such as treatment tracheitis, asthma, treating both the principal and secondary aspects of a disease, instant effect, the curative effect height, high safety, applied range, side effect is little.
Foregoing invention purpose of the present invention realizes by following technical method:
A kind of treat cough illness in, western compound recipe patent medicine, comprising: Radix Glycyrrhizae extractum powder, Bulbus Fritillariae Uninbracteatae powder, norfloxacin, aminophylline, prednisone, chlorphenamine, stable, Celenbuterol.
Described Radix Glycyrrhizae extractum powder is that pure Chinese herbal medicine Radix Glycyrrhizae processing refinement forms, Radix Glycyrrhizae is the root and rhizome of pulse family herbaceos perennial Radix Glycyrrhizae, main product in the Inner Mongol, ground such as Shanxi, Gansu, Xinjiang, excavate spring and autumn, remove residual stem and root hair, or remove crust, section is dried, and plays lung moistening, cough-relieving, antiasthmatic effect.The Radix Glycyrrhizae slightly warm in nature, its flavor can be separated toxicity to sweet, and this medicine combines the untoward reaction that can remove (mitigation) Western medicine with Western medicine, can strengthen the curative effect of curing the disease again.
Bulbus Fritillariae Uninbracteatae powder in the compound recipe patent medicine has the effect of cough-relieving, lung heat clearing, and is better with the effect of matching of Chinese herbal medicine Radix Glycyrrhizae.
Celenbuterol Zhichuan in the compound recipe patent medicine is renderd a service stronger 10 times than albuterol approximately, onset dosage is little, acting duration is long, safety range is big, be mainly used in bronchial asthma, asthmatic bronchitis etc., one time oral dose only just takes effect with the .00002 gram, with the collaborative horizontal phenomenon of nonreactive of all the other medicines, strengthens medicine therapy speed.
Aminophylline in the compound recipe patent medicine is that the bonded complex theophylline of theophylline and ethylenediamine is insoluble in water, and behind the adding ethylenediamine, water solublity increases, and has strengthened the bronchial effect coronarius of diastole of theophylline.Character: white or faint yellow granule or powder, bitter in the mouth, little have amine smelly, can be dissolved in water, and aqueous solution is alkalescence.Aminophylline has the curative effect of relievining asthma, can be oral, and littler to the side effect of heart excitement, convenient for production than adrenomimetic drug, become clinical the most frequently used one of medicine of bronchial asthma of preventing and treating in the present age.Aminophylline can strengthen myocardial contraction, the expansion coronary vasodilator, and more weak diuresis is arranged, can be used for congestive heart failure, cardiac edema, cardiac asthma, alleviation dyspnea etc.But if consumption is excessive, excessive concentration can cause the strong excitement of heart, dizziness, cardiopalmus, arrhythmia, even serious adverse reactions such as blood pressure sharp fall, convulsions.Radix Glycyrrhizae extractum powder in the compound recipe can be alleviated this untoward reaction, and the consumption in the compound recipe only is single with 1/2nd of minimum oral dose, can play curative effect preferably.Aminophylline has the central excitation effect, easily causes symptoms such as insomnia uneasiness, and stabilizing in the compound recipe patent medicine can solve this symptom, and strengthens the synergism of medicine, do not have the anti-horizontal effect with other medicines.
Norfloxacin in the compound recipe patent medicine is that off-white color is to light yellow crystalline powder, odorless, mildly bitter flavor, can absorb moisture in air, then the color gradual change is dark to meet light, soluble,very slightly in water or ethanol, main effect is the dna gyrase on antibacterial, make DNA of bacteria Qu Xuanzhuan cracking, the function of dna gyrase to the duplicating of whole DNA, transcribe, each stage such as reorganization all plays an important role, and is the essential condition of bacteria live.Norfloxacin can suppress above-mentioned functions, suppresses growth, breeding, the kill bacteria of antibacterial rapidly, and the pair cell wall has very strong osmosis, thereby bactericidal action strengthens more.Oral absorption is rapid, and in-vivo tissue distributes better after the administration, and the concentration in the tissue such as liver, kidney, lymph node also can be infiltrated in the skin ulcer liquid apparently higher than blood concentration, and successive administration does not have cumulative action.Oral oral general cephalosporin and other oral drugs of being better than of norfloxacin, as tetracycline, erythromycin etc.Because of tetracycline, erythromycin etc. has certain side effect, and many antibacterials produce drug resistance too much to these antibiotic, so acute and chronic tracheitis, asthma is indispensable with this medicine.The untoward reaction of norfloxacin: slight stomach discomfort, anorexia, feel sick, idol has dizzy, headache or erythra.
Chlorphenamine in the compound recipe patent medicine can be removed erythra, and prednisone can be removed slight stomach discomfort, and appetite stimulator has preventive and therapeutic effect to all anaphylactic diseases, and strengthens the curative effect of curing the disease, the untoward reaction of prophylactic agent.
A kind of treat cough illness in, the preparation method of western compound recipe patent medicine, may further comprise the steps:
After A, decocting extract the active ingredient of pure Chinese herbal medicine Radix Glycyrrhizae, under certain humidity, concentrate, make GANGCAO GAO, in the Radix Glycyrrhizae powder adding GANGCAO GAO with porphyrize, dry, make Radix Glycyrrhizae extractum powder;
B, under aseptic situation, with Western medicine norfloxacin, aminophylline, prednisone, chlorphenamine, stable, Celenbuterol mixes with Radix Glycyrrhizae extractum powder, Bulbus Fritillariae Uninbracteatae powder, porphyrize, mix well;
C, adding antiseptic, packaged sterile.
Below describe preparation process of the present invention in detail: get the Chinese herbal medicine Radix Glycyrrhizae, behind clear water immersion twenty four hours, decocted 2~4 hours, leach decocting liquid, add clear water again and decoct three times continuously, under 75~85 ℃, concentrate, make GANGCAO GAO, Radix Glycyrrhizae powder with porphyrize adds in the GANGCAO GAO then, dries, and makes Radix Glycyrrhizae extractum powder; Under aseptic situation, Western medicine Celenbuterol, aminophylline, stable, norfloxacin, chlorphenamine, prednisone and Radix Glycyrrhizae extractum powder, Bulbus Fritillariae Uninbracteatae powder are mixed, porphyrize, mix well by the component weight ratio; Add antiseptic, packaged sterile.
In order to guarantee the effect of antiinflammatory, Zhichuan, antitussive, reduce toxicity simultaneously, each component adds ratio of weight and number: Radix Glycyrrhizae extractum powder: 120~160, Bulbus Fritillariae Uninbracteatae powder: 50~70, norfloxacin: 40~60, aminophylline: 30~40, prednisone: 1.6~2, chlorphenamine: 1.3~1.6, stable: 0.4~0.6, Celenbuterol: 0.014~0.016.
Radix Glycyrrhizae thickening temperature described in this manufacture method is 75~85 ℃, and described antiseptic can be used benzoic acid, sodium benzoate etc.
This compound recipe patent medicine has the effect of antiinflammatory, Zhichuan, antitussive, for diseases such as treatment tracheitis, asthma, treating both the principal and secondary aspects of a disease, instant effect; The curative effect height, high safety, applied range, side effect is little.
Below in conjunction with embodiment the present invention is done further detailed description:
Embodiment 1:
Prepare a kind of treat cough illness in, the method for western compound recipe patent medicine, may further comprise the steps:
A. after decocting extracts the active ingredient of pure Chinese herbal medicine Radix Glycyrrhizae, concentrate down, make GANGCAO GAO, in the Radix Glycyrrhizae powder adding GANGCAO GAO with porphyrize, dry, make Radix Glycyrrhizae extractum powder at 78~80 ℃;
B. under aseptic situation, with each component by add portion rate: Radix Glycyrrhizae extractum powder: 153, Bulbus Fritillariae Uninbracteatae powder: 60, norfloxacin: 60, aminophylline: 40, prednisone: 2, chlorphenamine: 1.6, stable: 0.6, Celenbuterol: 0.016, mixing, porphyrize, mix well;
C. add preservative benzoic acid, packaged sterile.
Embodiment 2:
Preparation method is with embodiment 1, and each component is by adding ratio of weight and number: Radix Glycyrrhizae extractum powder: 120, Bulbus Fritillariae Uninbracteatae powder: 50, norfloxacin: 40, aminophylline: 30, prednisone: 1.6, chlorphenamine: 1.3, stable: 0.4, Celenbuterol: 0.014.
Embodiment 3:
Preparation method is with embodiment 1, and each component is by adding ratio of weight and number: Radix Glycyrrhizae extractum powder: 140, Bulbus Fritillariae Uninbracteatae powder: 60, norfloxacin: 50, aminophylline: 35, prednisone: 1.6, chlorphenamine: 1.4, stable: 0.5, Celenbuterol: 0.015.
Embodiment 4:
Preparation method is with embodiment 1, and each component is by adding ratio of weight and number: Radix Glycyrrhizae extractum powder: 150, Bulbus Fritillariae Uninbracteatae powder: 60, norfloxacin: 55, aminophylline: 35, prednisone: 1.8, chlorphenamine: 1.6, stable: 0.6, Celenbuterol: 0.016.
Embodiment 5:
Preparation method is with embodiment 1, and each component is by adding ratio of weight and number: Radix Glycyrrhizae extractum powder: 160, Bulbus Fritillariae Uninbracteatae powder: 70, norfloxacin: 60, aminophylline: 40, prednisone: 2, chlorphenamine: 1.6, stable: 0.6, Celenbuterol: 0.016.
Claims (4)
1, a kind of treat cough illness in, western compound recipe patent medicine, it is characterized in that it is made up of following compositions in weight portion: Radix Glycyrrhizae extractum powder 120-160, Bulbus Fritillariae Uninbracteatae powder 50-70, norfloxacin 40-60, aminophylline 30-40, prednisone 1.6-2, chlorphenamine 1.3-1.6, stable 0.4-0.6, Celenbuterol 0.014-0.016; Wherein Radix Glycyrrhizae extractum powder makes with following method: after decocting extracts the active ingredient of pure Chinese herbal medicine Radix Glycyrrhizae, concentrate at a certain temperature, make GANGCAO GAO, in the Radix Glycyrrhizae powder adding GANGCAO GAO with porphyrize, dry, make Radix Glycyrrhizae extractum powder.
2, according to claim 1 a kind of treat cough illness in, western compound recipe patent medicine, it is characterized in that described Radix Glycyrrhizae thickening temperature is 75~85 ℃.
3, claim 1 described a kind of treat cough illness in, the preparation method of western compound recipe patent medicine, may further comprise the steps:
A, under aseptic situation, with Western medicine norfloxacin, aminophylline, prednisone, chlorphenamine, stable, Celenbuterol mixes with Radix Glycyrrhizae extractum powder, Bulbus Fritillariae Uninbracteatae powder, porphyrize, mix well;
B, adding antiseptic, packaged sterile.
4, according to claim 3 a kind of treat cough illness in, the preparation method of western compound recipe patent medicine, it is characterized in that described antiseptic can use benzoic acid, sodium benzoate etc.
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CN99112280A CN1090959C (en) | 1999-06-17 | 1999-06-17 | Patent medicine contg. triditional Chinese medicine and western medicine for treating cough and asthma disease |
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CN99112280A CN1090959C (en) | 1999-06-17 | 1999-06-17 | Patent medicine contg. triditional Chinese medicine and western medicine for treating cough and asthma disease |
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CN1277866A CN1277866A (en) | 2000-12-27 |
CN1090959C true CN1090959C (en) | 2002-09-18 |
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CN99112280A Expired - Fee Related CN1090959C (en) | 1999-06-17 | 1999-06-17 | Patent medicine contg. triditional Chinese medicine and western medicine for treating cough and asthma disease |
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Families Citing this family (2)
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CA2909117A1 (en) * | 2013-04-09 | 2014-10-16 | Cresset Biomolecular Discovery Ltd | The treatment of inflammatory disorders |
CN104840719A (en) * | 2015-05-15 | 2015-08-19 | 孟智琴 | Medicament for treating bronchitis |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1162484A (en) * | 1997-03-28 | 1997-10-22 | 刘广清 | Compounded Chuanlin Dingchuan capsule for asthma |
CN1172667A (en) * | 1997-08-15 | 1998-02-11 | 刘福印 | Medicine for treating bronchitis and its preparing method |
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1162484A (en) * | 1997-03-28 | 1997-10-22 | 刘广清 | Compounded Chuanlin Dingchuan capsule for asthma |
CN1172667A (en) * | 1997-08-15 | 1998-02-11 | 刘福印 | Medicine for treating bronchitis and its preparing method |
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