CN102552663A - Chinese herbal compound used for treating paraquat poisoning - Google Patents
Chinese herbal compound used for treating paraquat poisoning Download PDFInfo
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- CN102552663A CN102552663A CN2011103220372A CN201110322037A CN102552663A CN 102552663 A CN102552663 A CN 102552663A CN 2011103220372 A CN2011103220372 A CN 2011103220372A CN 201110322037 A CN201110322037 A CN 201110322037A CN 102552663 A CN102552663 A CN 102552663A
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Abstract
The objective of the invention is to provide a Chinese herbal compound used for treating paraquat poisoning. According to the invention, Chinese traditional treatment theories of invigoration of blood, removal of stasis, elimination of necrotic tissue, engendering of flesh, nourishment to the lung, promotion of blood circulation, protection of the liver and the kidney and the like are used as support, and by nourishing and invigorating blood, human immunity is enhanced, self-repairing capacity and transporting and digesting functions of visceral organs are improved and formation of pulmonary fibrosis is inhibited. The Chinese herbal compound comprises gecko, Chinese caterpillar fungus, dysosma pleiantha, tendril-leaved fritillary bulb, Artemisia capillaris, rhizome anemones altaicae, cassia twig, white peony root, vegetable sponge of luffa, Eclipta alba, dark plum, ginseng, donkey-hide gelatin and furnace soil.
Description
Technical field
The present invention relates to a kind of Chinese medicine compound that is used to treat paraquat poisoning, belong to the pharmaceutical formulation technical field.
Background technology
N,N'-dimethyl-.gamma..gamma.'-dipyridylium belongs to the organic nitrogen heterocycle compound, and effective ingredient is 1,1 dimethyl-4; 4 second bipyridine cationic salts, pure article are white crystal, and are tasteless; Soluble in water; Gramoxone, Aerial gramoxone, prairie fire, hundred, Ba La multiple trade name such as stop is arranged again, is a kind of quick steriland herbicide, has action of contace poison and certain systemic action.Can make it withered rapidly by the green plant tissue absorption.N,N'-dimethyl-.gamma..gamma.'-dipyridylium is very big to people's toxicity, can be through mucocutaneous, respiratory tract and gastrointestinal absorption, and its infiltration rate and drainage rate are very fast, and infiltration rate is higher in lung.Oral or contact skin all can make the people poison, and the adult estimates that lethal dose 20% aqueous solution is about about 5～15ml.Intoxicating phenomenon is that skin, oral cavity, throat, mucous membrane of esophagus that warp contacts with N,N'-dimethyl-.gamma..gamma.'-dipyridylium have corrosion and fester, and causes multiple organ failure, MOFs such as liver, kidney, lung fibrosis and respiratory failure.After generally poisoning, the report case dies from organ failure or pulmonary fibrosis in day at 1-20.Because of unclear symptoms in the poisoning previous tretament golden period shows, the easy mistaken diagnosis or the ignorance state of an illness.Because of still not having the specially good effect antidote in the world, general poisoning survival rate is at 5-10%, and the cure rate of utmost point individual hospitals is declared at 30-50%.Because cognitive not enough to paraquat poisoning, the mortality rate of the provinces and cities' paraquat poisoning that has even be 100%.According to incompletely statistics, big agricultural province such as Hebei, Henan, Sichuan, Liaoning, Anhui, its County Hospital case of seeing and treating patients is general annual in the 10-30 example, and every year is died from the paraquat poisoning in the preresearch estimates whole nation, and the person reaches 1000-2500 people.
The inventor holds remote countryside, in the secular career of practising medicine, has accumulated the method with all kinds of pesticide of treatment by Chinese herbs, Tetramine and paraquat poisoning gradually.Causing the mechanism that the people damages to paraquat poisoning, is support with the Chinese traditional treatment theory, adopts drug matching, has treated 160 routine paraquat poisoning persons in all parts of the country, 129 examples of fully recovering, and cure rate is 80.6%.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine compound of treating paraquat poisoning; With blood circulation promoting and blood stasis dispelling, removing the necrotic tissue and promoting granulation, to support the logical Lip river of lung, protect the liver Chinese traditional treatment theories such as protecting kidney be support; Through nourshing blood and promoting blood circulation; The enhances human body resistance improves internal organs self-repairing capability and fortuneization function, the formation of opposing pulmonary fibrosis.
Technical scheme of the present invention is achieved in that Chinese medicine compound of the present invention, it is characterized in that being processed by following bulk drugs:
Gecko 10-30 gram, Cordyceps 10-30 gram, Radix et Rhizoma Dysosmatis 10-30 gram, Bulbus Fritillariae Cirrhosae 10-30 gram, Herba Artemisiae Scopariae 5-15 gram, Rhizoma Anemones Altaicae 5-15 gram, Ramulus Cinnamomi 5-15 gram, Radix Paeoniae Alba 5-20 gram, Retinervus Luffae Fructus 5-15 gram, Herba Ecliptae 5-15 gram, Fructus Mume 5-15 gram, Radix Ginseng 5-15 gram, Colla Corii Asini 5-15 gram, humus flava usta 5-20 gram.
Described Chinese medicine compound optimum combination ratio comprises:
Gecko 10-20 gram, Cordyceps 10-20 gram, Radix et Rhizoma Dysosmatis 10-20 gram, Bulbus Fritillariae Cirrhosae 10-20 gram, Herba Artemisiae Scopariae 5-10 gram, Rhizoma Anemones Altaicae 5-10 gram, Ramulus Cinnamomi 5-10 gram, Radix Paeoniae Alba 1-20 gram, Retinervus Luffae Fructus 5-10 gram, Herba Ecliptae 5-10 gram, Fructus Mume 5-10 gram, Radix Ginseng 5-10 gram, Colla Corii Asini 5-10 gram, humus flava usta 10-15 gram.
Described Chinese medicine compound can be processed any be used to clinically the treat dosage form that paraquat poisoning uses, for example oral medicine preparation, tablet, capsule, powder, pill, effervescent tablet etc.In view of the characteristics of paraquat poisoning, liquid preparation is easier to absorb, so the preferred liquid preparation uses.
Described Chinese medicine compound has been treated 160 routine paraquat poisoning persons in all parts of the country altogether at 2009-2011,129 examples of fully recovering, and dead 31 examples (confirming dead 17 people, 14 people out of touch), cure rate is 80.6%.
The 2009-2011 paraquat poisoning is cured the case statistical table
The specific embodiment
Below in conjunction with the instance of Chinese medicine composition of the present invention, the specific embodiment of the present invention is described.
Embodiment:
1, Gecko 15 grams, Cordyceps 15 grams, Radix et Rhizoma Dysosmatis 15 grams, Bulbus Fritillariae Cirrhosae 10 grams, Herba Artemisiae Scopariae 5 grams, Rhizoma Anemones Altaicae 5 grams, Ramulus Cinnamomi 8 grams, the Radix Paeoniae Alba 8 grams, Retinervus Luffae Fructus 5 grams, Herba Ecliptae 10 grams, Fructus Mume 5 grams, Radix Ginseng 10 grams, Colla Corii Asini 10 grams, humus flava usta 10 grams.
2, Gecko 10 grams, Cordyceps 10 grams, Radix et Rhizoma Dysosmatis 15 grams, Bulbus Fritillariae Cirrhosae 10 grams, Herba Artemisiae Scopariae 8 grams, Rhizoma Anemones Altaicae 5 grams, Ramulus Cinnamomi 8 grams, the Radix Paeoniae Alba 8 grams, Retinervus Luffae Fructus 5 grams, Herba Ecliptae 7 grams, Fructus Mume 5 grams, Radix Ginseng 15 grams, Colla Corii Asini 10 grams, humus flava usta 10 grams.
3, Gecko 10 grams, Cordyceps 15 grams, Radix et Rhizoma Dysosmatis 15 grams, Bulbus Fritillariae Cirrhosae 10 grams, Herba Artemisiae Scopariae 8 grams, Rhizoma Anemones Altaicae 5 grams, Ramulus Cinnamomi 8 grams, the Radix Paeoniae Alba 10 grams, Retinervus Luffae Fructus 5 grams, Herba Ecliptae 7 grams, Fructus Mume 5 grams, Radix Ginseng 15 grams, Colla Corii Asini 10 grams, humus flava usta 15 grams.
Claims (6)
1. Chinese medicine compound of treating paraquat poisoning is characterized in that the crude drug for preparing its active ingredient comprises:
Gecko 10-20 gram, Cordyceps 10-20 gram, Radix et Rhizoma Dysosmatis 10-20 gram, Bulbus Fritillariae Cirrhosae 10-20 gram, Herba Artemisiae Scopariae 5-10 gram, Rhizoma Anemones Altaicae 5-10 gram, Ramulus Cinnamomi 5-10 gram, Radix Paeoniae Alba 1-20 gram, Retinervus Luffae Fructus 5-10 gram, Herba Ecliptae 5-10 gram, Fructus Mume 5-10 gram, Radix Ginseng 5-10 gram, Colla Corii Asini 5-10 gram, humus flava usta 10-15 gram.
2. the Chinese medicine compound of treatment paraquat poisoning according to claim 1, the crude drug that wherein prepares its active ingredient comprises: Gecko 15 grams, Cordyceps 15 grams, Radix et Rhizoma Dysosmatis 15 grams, Bulbus Fritillariae Cirrhosae 10 grams, Herba Artemisiae Scopariae 5 grams, Rhizoma Anemones Altaicae 5 grams, Ramulus Cinnamomi 8 grams, the Radix Paeoniae Alba 8 grams, Retinervus Luffae Fructus 5 grams, Herba Ecliptae 10 grams, Fructus Mume 5 grams, Radix Ginseng 10 grams, Colla Corii Asini 10 grams, humus flava usta 10 grams.
3. the Chinese medicine compound of treatment paraquat poisoning according to claim 1, the crude drug that wherein prepares its active ingredient comprises: Gecko 10 grams, Cordyceps 10 grams, Radix et Rhizoma Dysosmatis 15 grams, Bulbus Fritillariae Cirrhosae 10 grams, Herba Artemisiae Scopariae 8 grams, Rhizoma Anemones Altaicae 5 grams, Ramulus Cinnamomi 8 grams, the Radix Paeoniae Alba 8 grams, Retinervus Luffae Fructus 5 grams, Herba Ecliptae 7 grams, Fructus Mume 5 grams, Radix Ginseng 15 grams, Colla Corii Asini 10 grams, humus flava usta 10 grams.
4. the Chinese medicine compound of treatment paraquat poisoning according to claim 1, the crude drug that wherein prepares its active ingredient comprises: Gecko 10 grams, Cordyceps 15 grams, Radix et Rhizoma Dysosmatis 15 grams, Bulbus Fritillariae Cirrhosae 10 grams, Herba Artemisiae Scopariae 8 grams, Rhizoma Anemones Altaicae 5 grams, Ramulus Cinnamomi 8 grams, the Radix Paeoniae Alba 10 grams, Retinervus Luffae Fructus 5 grams, Herba Ecliptae 7 grams, Fructus Mume 5 grams, Radix Ginseng 15 grams, Colla Corii Asini 10 grams, humus flava usta 15 grams.
5. according to the Chinese medicine compound of the treatment paraquat poisoning described in the claim 1-4, it is characterized in that described compound recipe is the oral formulations form.
6. according to the Chinese medicine compound of the treatment paraquat poisoning described in the claim 5, it is characterized in that described compound recipe is tablet, capsule, powder, pill, effervescent tablet dosage form.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011103220372A CN102552663B (en) | 2011-10-15 | 2011-10-15 | Chinese herbal compound used for treating paraquat poisoning |
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| CN2011103220372A CN102552663B (en) | 2011-10-15 | 2011-10-15 | Chinese herbal compound used for treating paraquat poisoning |
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| CN102552663A true CN102552663A (en) | 2012-07-11 |
| CN102552663B CN102552663B (en) | 2013-12-04 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547384A (en) * | 2015-02-08 | 2015-04-29 | 刘冬松 | Oral liquid for treating paraquat poisoning and preparation method of oral liquid |
| CN105169099A (en) * | 2015-09-09 | 2015-12-23 | 陕西博世康医药科技有限公司 | Traditional Chinese medicine recovery formula for curing paraquat poisoning |
| CN106266562A (en) * | 2016-08-30 | 2017-01-04 | 刘峰亭 | A kind of pharmaceutical composition for treating paraquat poisoning |
| CN113559141A (en) * | 2021-08-11 | 2021-10-29 | 内蒙古民族大学 | Application of artemisia capillaris for preparing medicine for treating pulmonary fibrosis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152507A (en) * | 2007-09-28 | 2008-04-02 | 丁文生 | Traditional Chinese medicine for treating infantile pneumonia with syndrome of lingering pathogen due to deficiency of vital qi |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152507A (en) * | 2007-09-28 | 2008-04-02 | 丁文生 | Traditional Chinese medicine for treating infantile pneumonia with syndrome of lingering pathogen due to deficiency of vital qi |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547384A (en) * | 2015-02-08 | 2015-04-29 | 刘冬松 | Oral liquid for treating paraquat poisoning and preparation method of oral liquid |
| CN105169099A (en) * | 2015-09-09 | 2015-12-23 | 陕西博世康医药科技有限公司 | Traditional Chinese medicine recovery formula for curing paraquat poisoning |
| CN106266562A (en) * | 2016-08-30 | 2017-01-04 | 刘峰亭 | A kind of pharmaceutical composition for treating paraquat poisoning |
| CN113559141A (en) * | 2021-08-11 | 2021-10-29 | 内蒙古民族大学 | Application of artemisia capillaris for preparing medicine for treating pulmonary fibrosis |
| CN113559141B (en) * | 2021-08-11 | 2022-09-13 | 内蒙古民族大学 | Application of artemisia capillaris for preparing medicine for treating pulmonary fibrosis |
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| CN102552663B (en) | 2013-12-04 |
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