CN109085278B - 液相色谱串联质谱法同时检测多种氨基酸的试剂盒及其应用 - Google Patents
液相色谱串联质谱法同时检测多种氨基酸的试剂盒及其应用 Download PDFInfo
- Publication number
- CN109085278B CN109085278B CN201810884890.5A CN201810884890A CN109085278B CN 109085278 B CN109085278 B CN 109085278B CN 201810884890 A CN201810884890 A CN 201810884890A CN 109085278 B CN109085278 B CN 109085278B
- Authority
- CN
- China
- Prior art keywords
- acid
- amino acids
- internal standard
- kit
- liquid chromatography
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810884890.5A CN109085278B (zh) | 2018-08-06 | 2018-08-06 | 液相色谱串联质谱法同时检测多种氨基酸的试剂盒及其应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810884890.5A CN109085278B (zh) | 2018-08-06 | 2018-08-06 | 液相色谱串联质谱法同时检测多种氨基酸的试剂盒及其应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN109085278A CN109085278A (zh) | 2018-12-25 |
CN109085278B true CN109085278B (zh) | 2020-04-14 |
Family
ID=64833965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810884890.5A Active CN109085278B (zh) | 2018-08-06 | 2018-08-06 | 液相色谱串联质谱法同时检测多种氨基酸的试剂盒及其应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109085278B (zh) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110018266B (zh) * | 2019-02-15 | 2022-03-04 | 广州市妇女儿童医疗中心 | 一种快速定量分析48种氨基酸的方法 |
CN110133124A (zh) * | 2019-04-29 | 2019-08-16 | 天津中医药大学 | 疏血通注射液中18种氨基酸的含量测定方法 |
CN110806458A (zh) * | 2019-11-29 | 2020-02-18 | 北京和合医学诊断技术股份有限公司 | 同时检测血液中亮氨酸、异亮氨酸和缬氨酸含量的方法 |
CN111693624B (zh) * | 2020-06-22 | 2021-07-09 | 南京市中医院 | 一种与儿童多发性抽动症诊断相关的血浆代谢标志物在制备儿童多发性抽动症诊断试剂盒中的应用 |
CN113030327B (zh) * | 2021-03-12 | 2022-03-25 | 杭州度安医学检验实验室有限公司 | 一种基于hplc-ms/ms诊断泌尿结石的试剂盒和应用 |
CN113030338A (zh) * | 2021-04-01 | 2021-06-25 | 贵州中烟工业有限责任公司 | 一种测定烟丝中氨基酸的方法 |
CN114236025B (zh) * | 2021-12-09 | 2023-09-01 | 浙江博圣生物技术股份有限公司 | 不使用离子对试剂和非衍生化测定43种氨基酸的方法 |
CN114280204A (zh) * | 2021-12-22 | 2022-04-05 | 深圳天祥质量技术服务有限公司 | 一种鉴别动物源物品的液相色谱串联质谱筛查方法 |
CN114487229A (zh) * | 2022-02-09 | 2022-05-13 | 杭州佰辰医疗器械有限公司 | 一种血浆和血清内源性小分子化合物质控品配制方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108333268A (zh) * | 2018-01-30 | 2018-07-27 | 济南英盛生物技术有限公司 | 一种同时检测干血斑、血液和尿液中四十种氨基酸的方法 |
-
2018
- 2018-08-06 CN CN201810884890.5A patent/CN109085278B/zh active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108333268A (zh) * | 2018-01-30 | 2018-07-27 | 济南英盛生物技术有限公司 | 一种同时检测干血斑、血液和尿液中四十种氨基酸的方法 |
Non-Patent Citations (3)
Title |
---|
浓缩果汁中20种氨基酸的超高效液相色谱-串联质谱法同时测定;孔祥虹 等;《分析测试学报》;20100430;第29卷(第4期);全文 * |
液相色谱-串联质谱法检测3例特应性皮炎患者的氨基酸、有机酸、脂肪酸代谢情况分析;王佳曼 等;《皮肤性病诊疗学杂志》;20130831;第20卷(第4期);第222-223页 * |
稳定同位素稀释超高效液相-串联质谱联用法同时测定人血清中13 种氨基酸的含量;时正媛 等;《中国临床药理学杂志》;20180531;第34卷(第9期);摘要,第1109-1110页 * |
Also Published As
Publication number | Publication date |
---|---|
CN109085278A (zh) | 2018-12-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN109085278B (zh) | 液相色谱串联质谱法同时检测多种氨基酸的试剂盒及其应用 | |
JP7399214B2 (ja) | 液体クロマトグラフィー質量分析による体液中のアミノ酸分析 | |
CN108645924B (zh) | 基于超高效液相色谱串联质谱技术的新生儿代谢物的检测方法 | |
CN106442758A (zh) | 非衍生化检测人体血浆中多种氨基酸的液相质谱方法 | |
CA2651227C (en) | Quantitative analysis of surface-derived samples using mass spectrometry | |
CN108333268A (zh) | 一种同时检测干血斑、血液和尿液中四十种氨基酸的方法 | |
CN109633030A (zh) | 一种超高效液相色谱-串联四级杆质谱检测动物体液或组织样本中氨基酸的方法 | |
CN113480599A (zh) | 一种鉴别梅花鹿或马鹿鹿角胶的特征多肽及其应用 | |
CN113063871B (zh) | 一种代谢小分子检测方法及检测系统 | |
US20110240843A1 (en) | Methods for detecting catecholamines by mass spectrometry | |
EP2517016A1 (en) | Method and kit for determining metabolites on dried blood spot samples | |
US7700364B2 (en) | Analysis of amino acids in body fluid by liquid chromatography-mass spectrometry | |
CN113125601B (zh) | 一种同时检测血清中4种脂溶性维生素的浓度的方法 | |
CN112730723A (zh) | 一种超高效液相色谱-串联质谱检测血浆中22种游离氨基酸的方法 | |
CN111830146A (zh) | 一种干血片中25-羟基维d的lc-ms/ms高通量检测方法及试剂盒 | |
Wenner et al. | Factors that affect ion trap data-dependent MS/MS in proteomics | |
CN113607854A (zh) | 同时检测多种维生素的方法和检测试剂盒 | |
CN114019034A (zh) | 一种游离氨基酸快速非衍生的液相色谱串联质谱检测方法 | |
CN113655223A (zh) | 多重氨基酸定量方法及试剂盒研制 | |
CN112526048B (zh) | 一种快速检测环境沉积物中高血压药物痕量残留的方法 | |
CN109342627B (zh) | 一种细胞培养物中氨基酸的检测方法 | |
CN114624338A (zh) | 利用液相色谱-串联质谱定量分析生物样本中游离氨基酸的方法 | |
CN113302499A (zh) | 用于基于LC-MS的HbA1c测量的高速样品工作流程 | |
CN113330314A (zh) | 用于关于完整蛋白质水平的基于LC-MS的HbA1c测量的自动化样品工作流程 | |
CN109324139A (zh) | 一种烟叶中玉米素核苷液液萃取-液相色谱-串联质谱的测定方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CP01 | Change in the name or title of a patent holder |
Address after: 311103 401s, No. 22, Xinyan Road, Yuhang Economic Development Zone, Hangzhou, Zhejiang Patentee after: Hangzhou Baichen Medical Instrument Co.,Ltd. Patentee after: HANGZHOU BAICHEN MEDICAL LABORATORY Co.,Ltd. Address before: 311103 401s, No. 22, Xinyan Road, Yuhang Economic Development Zone, Hangzhou, Zhejiang Patentee before: HANGZHOU BAIQIN MEDICAL EQUIPMENT Co.,Ltd. Patentee before: HANGZHOU BAICHEN MEDICAL LABORATORY Co.,Ltd. |
|
CP01 | Change in the name or title of a patent holder | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Kit for simultaneous detection of multiple amino acids by liquid chromatography tandem mass spectrometry and its application Effective date of registration: 20211206 Granted publication date: 20200414 Pledgee: CITIC Bank Limited by Share Ltd. Hangzhou branch Pledgor: HANGZHOU BAICHEN MEDICAL LABORATORY Co.,Ltd. Registration number: Y2021330002459 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |