CN1090497A - Antiscolic and manufacture method - Google Patents
Antiscolic and manufacture method Download PDFInfo
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- CN1090497A CN1090497A CN 93101034 CN93101034A CN1090497A CN 1090497 A CN1090497 A CN 1090497A CN 93101034 CN93101034 CN 93101034 CN 93101034 A CN93101034 A CN 93101034A CN 1090497 A CN1090497 A CN 1090497A
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- antiscolic
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Abstract
Antiscolic of the present invention is the broad-spectrum anti-parasite Chinese patent medicine that can make multiple dosage form.Be a few flavor Chinese medicines to be concocted respectively, pulverized and make through mixing.Take low dose and can effect a radical cure ascarid, pinworm, ancylostome, cestode, fasciloopsis, flagellate parasitic disease such as (comprising infusorian) effectively.Taking convenience, nontoxic, side effect.The various disease conditions that belongs to the traditional Chinese medical science " phlegm retention " category all can be amplified application, and can receive good efficacy.
Description
Antiscolic of the present invention and manufacture method belong to field of traditional Chinese.
Because the pollution of environment, the living habit that the backwardness of sanitary installation and people are bad makes parasitic disease the incidence of infection very high.At present, the first-selected Western medicine of broad-spectrum anti-parasite that is used for the treatment of parasitic disease clinically has that " piperazine citrate, " Anthelvet ", " povan ", " levamisole ", " mebendazole " reach " metronidazole " etc.Curative effect is considerable, but all have in the therapeutic dose nauseating, toxicity, side effect such as vomiting, stomachache, diarrhoea, erythra, dizzy, headache (" practical clinical medicine handbook)." SmithKline zental " (Albendazole's sheet) that Sino-America Tianjin Shike Pharmaceutical Co., Ltd. produces recently is the anti-helminth Western medicine of wide spectrum, but side effect such as headache, stomach upset are also arranged.Put down in writing in the successive dynasties books and periodicals relevantly control the worm Chinese medicinal formulae and have " chasing after the worm ball ", " Thunder God ball ", " wumei pills ", " green pepper prunus mume (sieb.) sieb.et zucc. ball ", " Flos Genkwa looses ", " chinaberry root looses ", " Lizhong Anhui Tang " reaches (" Chinese well-known doctor's prescription complete works ") such as " compound recipe thunder Chinese torreya balls ", effect all can, but medication is numerous and diverse, dosage is big, inconvenience is carried and children taking, and bright tool wide spectrum pest-resistant character.
The objective of the invention is to disclose a kind of taking convenience and broad-spectrum anti-parasite Chinese patent medicine nontoxic, side effect,, improve the cure rate of parasitic disease, reduce its incidence of infection so that in the control disease change of disease effectively of popular lesion.
It is Realgar and Semen Armeniacae Amarum that the medicine of antiscolic of the present invention is formed.Its manufacture method is this two herbal medicine to be concocted respectively be powder and mix homogeneously according to a certain ratio, be made as " powder ", and then available tradition or modern means, additional Mel, rice flour, sucrose, Cera Flava, water, vinegar, medicine juice, glycerol, gelatin, vaseline, liquid Paraffin or starch etc. are made dosage forms such as cake, ball, capsule, sheet, bolt or ointment.
The advantage of antiscolic of the present invention: the one, belong to the broad-spectrum anti-parasite medicine, ascarid, pinworm, ancylostome, cestode, fasciloopsis, sarcoptic mite and flagellate parasitic disease such as (comprising infusorian) all can be used; " the 2nd, the various disease conditions of the traditional Chinese medical science " phlegm retention " category all can be amplified application; The 3rd, clinical flexible route of administration is convenient in the variation of dosage form; The 4th, nontoxic, side effect.
Be that antiscolic of the present invention looses below, the specific embodiment of dosage forms such as cake, ball, capsule, sheet, bolt and ointment:
Form and manufacture method by said medicine, " powder " of antiscolic of the present invention is that Realgar and Semen Armeniacae Amarum two herbal medicines are formed.Wherein, Realgar is that water flies goods, and Semen Armeniacae Amarum is for pulverizing goods, all is made as Powderedly, and its degree of grinding is " impalpable powder " of new edition pharmacopeia regulation.Proportioning is 1: 1, and its mix homogeneously is " powder ".
Form and manufacture method by said medicine, the cake agent of antiscolic of the present invention is the solid preparation for oral administration that is mixed and made into as excipient and above-mentioned " powder " with rice flour and sucrose and Oleum sesami.Its ratio and method for making are: with Semen oryzae sativae 250 gram, Oryza glutinosa 250 grams, eluriating totally, cook, parching to brown, grind and be fine powder, go into 5 gram Oleum sesami, stir with above-mentioned " powder " 100 grams, is to be " mixing fine powders ".In addition that white sugar 283 grams and water are an amount of; make the suitable syrup of denseness; add in above-mentioned " mixing fine powders " that stirs; make " mixing fine powders " and the abundant fusion of syrup; get soft material and to granulation machine, make granule, granule is pressed in the model that spreads exsiccant " mixing fine powders ", take out and put the baking box baking; can take out (divide 50 fritters, every fritter contains " powder " 2 grams) to the hardening of cake piece bottom.
Form and manufacture method by said medicine, antiscolic pill of the present invention is that above-mentioned " powder " 500 grams and old honey 600 grams are stirred, and rubbing is made as the honeyed pill that every ball contains " powder " 2 grammes per square metres; Or add water with 200 gram Oryza glutinosa fine powders and steam and stick with paste, with above-mentioned " powder " 500 grams, make suitable soft material, be made as the paste pill that every ball contains " powder " 2 grams; Also can add above-mentioned " powder " 200 grams in the 200 gram Cera Flavas after fusing, mixing is put cold, makes the wax pill that every ball contains " powder " 2 grams when closely condensing; Also or spread " powder " on wet plaque, hold plaque and rotate, water spray, vinegar or medicine juice, last powder, palm brush is swept slowly, the general ball that is made as.
Form and manufacture method by said medicine, antiscolic capsule of the present invention is with 0-5 hard capsule or 1, No. 2 capsules of anus of packing into after the drying under above-mentioned " powder " 80 ° of temperature, makes enteric coated capsule.
Form and manufacture method by said medicine, the tablet of antiscolic of the present invention is to get above-mentioned " powder " to add the stirring rapidly of an amount of disintegrating agent (available 100 ° of exsiccant starch), binding agent (available Icing Sugar) and wetting agent (available 30%-50% ethanol), make suitable soft material, promptly with the wet grain of 16 mesh sieve systems, dry (60 °-80 °), the granulate that sieves adds lubricant (available 3%-6% Pulvis Talci) tabletting (0.5 gram) again.
Form and method for making by said medicine, the suppository of antiscolic of the present invention (vaginal suppository, rectal suppository) is to give the medicine molding with glycerol and glycerin gelatine (glycerol and gelatin etc. are heavy, and the heating in water bath fusion filters condensation), makes with hot melt.Get above-mentioned " powder " 200 grams, glycerol 300 grams, glycerin gelatine 500 grams.In above-mentioned " powder ", add glycerol earlier and be ground into " pastel ", in addition glycerin gelatine is put in the water-bath and heated, after waiting to melt, again above-mentioned " pastel " added, constantly stir, make it evenly, impouring had been coated with in the bolt mould of lubricant (available liquid Paraffin), unnecessary bolt piece is peelled off in cooling.Vaginal suppository can be made 200, is duckbill shape, diameter 1.5-2.5cm, and every heavy 5 grams contain " powder " 1 gram; Rectal suppository can be made 400, is the torpedo shape, long 2-3cm, and every heavy 2.5 grams contain " powder " 0.5 gram.
Form and manufacture method by said medicine, the ointment of antiscolic of the present invention is with vaseline 350 grams, glycerol 180 grams, and aqueous paraffin wax 270 grams are put water-bath fusing in the alms bowl, more above-mentioned " powder " 200 grams are added, and constantly stir, and make it mix homogeneously, cooling.
Claims (7)
1, a kind of broad-spectrum anti-parasite Chinese medicine preparation-antiscolic is characterized in that being its main constituent with Realgar and Semen Armeniacae Amarum.
2, a kind of manufacture method of broad-spectrum anti-parasite Chinese medicine preparation-antiscolic, it is characterized in that Realgar and Semen Armeniacae Amarum concocted respectively and be Powdered and mix homogeneously according to a certain ratio, be made as " powder ", and then with the tradition or the modern means of Chinese medicine preparation, additional excipients is made various dosage forms.
3, the manufacture method of Chinese medicine preparation-antiscolic according to claim 2, it is characterized in that said " concoct respectively " be meant Realgar through water fly, Semen Armeniacae Amarum is through pulverizing, and is made as powder.
4, the manufacture method of Chinese medicine preparation-antiscolic according to claim 2 is characterized in that the said Powdered medicine that is meant by new edition pharmacopeia regulation, and degree of grinding is " impalpable powder ".
5, the manufacture method of Chinese medicine preparation-antiscolic according to claim 2, the proportioning that it is characterized in that said pulverous Realgar and Semen Armeniacae Amarum can be 1: 1.
6, the manufacture method of Chinese medicine preparation-antiscolic according to claim 2, it is characterized in that the difference of said excipient according to dosage form, can be Mel, rice flour, sucrose, Cera Flava, water, vinegar, medicine juice, glycerol, gelatin, vaseline, liquid Paraffin or starch etc.
7, according to claim 1,2 described Chinese medicine preparation-antiscolic and manufacture methods, it is characterized in that said various dosage form can be loose, conventional dosage forms such as cake, ball, capsule, sheet, bolt, ointment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93101034 CN1090497A (en) | 1993-02-06 | 1993-02-06 | Antiscolic and manufacture method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93101034 CN1090497A (en) | 1993-02-06 | 1993-02-06 | Antiscolic and manufacture method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1090497A true CN1090497A (en) | 1994-08-10 |
Family
ID=4983376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93101034 Pending CN1090497A (en) | 1993-02-06 | 1993-02-06 | Antiscolic and manufacture method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1090497A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825709A (en) * | 2015-04-16 | 2015-08-12 | 湖州品创孵化器有限公司 | Traditional Chinese medicinal composition for treating parasitic diseases |
-
1993
- 1993-02-06 CN CN 93101034 patent/CN1090497A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825709A (en) * | 2015-04-16 | 2015-08-12 | 湖州品创孵化器有限公司 | Traditional Chinese medicinal composition for treating parasitic diseases |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |