CN104825709A - Traditional Chinese medicinal composition for treating parasitic diseases - Google Patents
Traditional Chinese medicinal composition for treating parasitic diseases Download PDFInfo
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- CN104825709A CN104825709A CN201510180044.1A CN201510180044A CN104825709A CN 104825709 A CN104825709 A CN 104825709A CN 201510180044 A CN201510180044 A CN 201510180044A CN 104825709 A CN104825709 A CN 104825709A
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating parasitic diseases. The composition comprises, by weight, 28-42 parts of apricot kernel, 18-28 parts of Cacumen Tamaricis, 6-10 parts of betel nut, 14-18 parts of pumpkin seed and 2-6 parts of realgar. In the invention, medicines complement each other to realize synergism, and have middle energizer warming, cold dispelling, qi tonifying, splenic yang invigorating, heat clearing, liver coursing, heat clearing and detoxifying, so the composition has substantial parasite killing, pathogenic factor dispelling, wind averting, sweat discharging and food stagnation removing efficacies on parasites in animal bodies, and also has the advantages of rapid action, fast effectiveness, short treatment cycle, high cure rate, obvious treatment effect on parasitic diseases, no toxic side effects, safety and reliability.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition can treating parasitic disease.
Background technology
Parasites in animals mainly contains ascarid, whipworm, oesophagostome, kidney nematicide, lung filaricide etc.; This several endoparasite is all larger to the harm of animal body; Migratory larvae destroys organizational structure and the physiological function of the intestinal wall of animal, liver and lungs, degradation under premunition; Vermin mainly contains demodicid mite, louse, Ticks, mosquito, fly etc.; Wherein maximum with the harm of acarid to pig; Except disturbing rhythm and pace of moving things orthobiosis of pig, reducing the price of deed and affect except the speed of growth of pig and the regularity of pig, and be the important disseminator of eperythrozoonosis etc. of the encephalitis B as pig of a lot of disease, parvovirus, pig, cause serious economic loss to pig industry.Endoparasite is owing to being hidden in animal body, and expeling difficulty is large compared with vermin.As carried out anthelmintic in body not in time, then can cause many symptoms such as host becomes thin, inappetence, anemia, malnutrition, hypoevolutism, diarrhoea, serious also can cause death.Thus, develop that a kind of toxic and side effects is little, the anthelmintic of successful, animal farming industry is had great importance.
At present, clinical treatment parasite medicine is of a great variety, but curative effect differs and side effect is large; But mostly have that therapeutic effect is undesirable, the course for the treatment of is longer, cost is higher, obstinate, the problem such as slowly of producing effects.And Chinese herbal medicine is pure natural substance, containing multiple biological effective components, as alkaloid, organic acid, tannin, saponin etc., there is antibacterial, antiviral, parasite killing, not easily produce drug resistance, the nontoxic or feature such as low toxicity, noresidue or low-residual, therefore, for the parasitic control of animal gastrointestinal tract, Chinese herbal medicine is selected to be better selection to its control.During two or more drug combination, if their action direction is consistent, reaches the effect strengthened each other and be called synergism.The intensity difference presented according to synergism can be divided into summation action and potentiation.When summation action is drug combination, its total effect equals the summation of each prescription used time effect.When potentiation is drug combination, its total effect exceedes the summation of each prescription used time effect.During drug combination, if their effect is contrary, reaches the effect weakening each other or disappear and be called antagonism.In Chinese medicine composition provided by the invention, the long-term practice through inventor draws, treatment by Chinese herbs parasitic disease has better effect, obtains good effect.Each medicine supplements and complements each other, mutually at synergism, play warming spleen and stomach for dispelling cold, benefiting qi and raising yang altogether, heat clearing away be soothing the liver, effect of heat-clearing and toxic substances removing, have parasite killing, remarkable healing curative effect by pathogen, aversion to wind sweating, eliminating stagnated food and killing intestinal worms to parasites in animals, effect is rapidly, rapid-action, short treating period, cure rate is high, has obvious curative effects to treatment parasitic disease, have no side effect, safe and reliable.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of parasitic disease, its good effect has no side effect.
Technical scheme of the present invention is as follows:
Treat a Chinese medicine composition for parasitic disease, it is characterized in that, comprise the component of following weight portion: Semen Armeniacae Amarum 28-42 part, Chinese Tamarisk Twing 18-28 part, Bin youth 6-10 part, Semen Cucurbitae 14-18 part, Realgar 2-6 part.
The component of following weight portion is preferably included: the component comprising following weight portion: 28 parts, Semen Armeniacae Amarum, Chinese Tamarisk Twing 18 parts, Semen Arecae 6 parts, Semen Cucurbitae 14 parts, Realgar 2 parts in the Chinese medicine composition of above-mentioned treatment parasitic disease.
The component of following weight portion is preferably included: 42 parts, Semen Armeniacae Amarum, Chinese Tamarisk Twing 28 parts, Semen Arecae 10 parts, Semen Cucurbitae 18 parts, Realgar 6 parts in the Chinese medicine composition of above-mentioned treatment parasitic disease.
The component of following weight portion is preferably included: 34 parts, Semen Armeniacae Amarum, Chinese Tamarisk Twing 22 parts, Semen Arecae 7 parts, Semen Cucurbitae 16 parts, Realgar 4 parts in the Chinese medicine composition of above-mentioned treatment parasitic disease.
The component of following weight portion is preferably included: 38 parts, Semen Armeniacae Amarum, Chinese Tamarisk Twing 24 parts, Semen Arecae 9 parts, Semen Cucurbitae 16 parts, Realgar 5 parts in the Chinese medicine composition of above-mentioned treatment parasitic disease.
Present invention also offers above-mentioned a kind of preparation method for the treatment of the Chinese medicine composition of parasitic disease, comprise the steps: to get Semen Armeniacae Amarum 28-42 part in formula, Chinese Tamarisk Twing 18-28 part, Semen Arecae 6-10 part, Semen Cucurbitae 14-18 part, Realgar 2-6 part, after adding 10 times amount soak with ethanol 14-20 hours, add 12-16 times amount water boiling and extraction 3-5 time, each 0.5-1 hour, merge extractive liquid, filter, after concentrating under reduced pressure, concentrated solution adopts suitable quantity of water dilution, ultrafiltration, ultrafiltrate is concentrated into relatively for density is the thick paste of 1.20-1.45, drying under reduced pressure, obtained described Chinese medicine composition.
Present invention also offers above-mentioned a kind of preparation for the treatment of the Chinese medicine composition of parasitic disease, it is characterized in that, described preparation is powder, pill, tablet, capsule, granule or injection.
Present invention also offers the above-mentioned a kind of application of Chinese medicine composition in preparation treatment parasitic disease product for the treatment of parasitic disease.
In the present invention, the pharmacological property of each raw material is as follows:
Aster panduratus Nees ex Walper: meridian distribution of property and flavor: bitter, pungent, temperature.Warming spleen and stomach for dispelling cold, cough-relieving, pain relieving.For phlegm dyspnea of coughing, chronic gastralgia, has loose bowels.Effect: promoting the circulation of QI to relieve pain, relieving cough and asthma.Cure mainly: by uncomfortable in chest, hypochondriac pain, abdominal distention, the colic of cold type stomachache controlled caused by the cold strongly fragrant stagnation of QI, the diseases such as dysmenorrhea.With control accumulation and obstruction of sputum, dyspnea and cough due to adverse raising of QI, septum pectorale full vexed, thin sputum is thin, the partially cold person of cough with asthma.
Semen Armeniacae Amarum: bitter, tepor; Slightly poisonous.Relieving cough and asthma, loosening bowel to relieve constipation.
Semen Arecae: bitter in the mouth, pungent, warm in nature, enters spleen, stomach, large intestine channel, has parasite killing, removing mass, the therapeutic method to keep the adverse QI flowing downwards, the effect of row water, cure mainly malnutrition due to parasitic infestation, dyspepsia, abdominal distention, heavy after dysentery, malaria.
Semen Cucurbitae: sweet in the mouth, warm in nature, enters spleen, stomach warp; There is invigorating the spleen and replenishing QI, anti-inflammatory analgetic, removing toxic substances parasite killing, effect that blood sugar lowering quenches the thirst; Cure mainly the diseases such as the prolonged illness deficiency of vital energy, weakness of the spleen and stomach, shortness of breath and lassitude, loose stool, diabetes, ascarid.
Chinese Tamarisk Twing: nature and flavor: sweet, salty, flat.Gui Jing: the popular feeling, lung, stomach three warp.Diaphoresis, antipyretic, rash, diuresis; Also can cough-relieving (Aqueous extracts lumbar injection has antitussive action to white mice) and antibacterial (Aqueous extracts has certain bacteriostasis in vitro to streptococcus pneumoniae, alpha streptococcus, white grapes ball castor, hemophilus influenza).Diaphoresis is examined thoroughly, removing toxic substances, diuresis.Cure mainly: measles is thoroughly difficult, and dysuria, alcoholic intoxication, washes skin pruritus due to wind pathogen.
Realgar: pungent taste, warm in nature.Return liver, large intestine channel.There is removing toxic substances parasite killing, removing dampness and eliminating phlegm, effect of preventing the attack (or recurrence) of malaria.Be usually used in carbuncle furuncle, snake bite and insect sting, abdominal pain due to worm stagnation, infantile convulsion, malaria.
The present invention adopts Semen Armeniacae Amarum, Semen Arecae, Semen Cucurbitae, Chinese Tamarisk Twing, the multiple medical material scientific combination of Realgar, each medicine supplements and complements each other, and mutually at synergism, plays warming spleen and stomach for dispelling cold, benefiting qi and raising yang altogether, heat clearing away is soothing the liver, effect of heat-clearing and toxic substances removing, to parasites in animals, there is parasite killing, remarkable healing curative effect by pathogen, aversion to wind sweating, eliminating stagnated food and killing intestinal worms, effect is rapidly, rapid-action, short treating period, cure rate is high, there is obvious curative effects to treatment parasitic disease, have no side effect, safe and reliable.Have the effect of Synergistic between Semen Armeniacae Amarum, Semen Arecae, Semen Cucurbitae, Chinese Tamarisk Twing, Realgar five kinds of medicines, lack wherein a herb arbitrarily, its curative effect all has obvious reduction, therefore complements each other between this Chinese medicine of the five flavours, indispensable.
Detailed description of the invention
Below in conjunction with embodiment, further illustrate content of the present invention.Should be appreciated that enforcement of the present invention is not limited to the following examples, any pro forma accommodation make the present invention and/or change all will fall into scope.
In the present invention, if not refer in particular to, all parts, percentage ratio are unit of weight, and all equipment and raw material etc. all can be buied from market or the industry is conventional.Method in following embodiment, if no special instructions, is the conventional method of this area.
Embodiment 1: a kind of Chinese medicine composition for the treatment of parasitic disease, comprises following component: Semen Armeniacae Amarum 38g, Chinese Tamarisk Twing 24g, Semen Arecae 9g, Semen Cucurbitae 16g, Realgar 5g.
Embodiment 2: a kind of Chinese medicine composition for the treatment of parasitic disease, comprises following component: Semen Armeniacae Amarum 42g, Chinese Tamarisk Twing 28g, Semen Arecae 10g, Semen Cucurbitae 18g, Realgar 6g.
Embodiment 3: a kind of Chinese medicine composition for the treatment of parasitic disease, comprises following component: Semen Armeniacae Amarum 34g, Chinese Tamarisk Twing 22g, Semen Arecae 7g, Semen Cucurbitae 16g, Realgar 4g.
Embodiment 4: a kind of Chinese medicine composition for the treatment of parasitic disease, comprises following component: Semen Armeniacae Amarum 28g, Chinese Tamarisk Twing 18g, Bin youth 6g, Semen Cucurbitae 14g, Realgar 2g.
Comparative example 1: a kind of Chinese medicine composition for the treatment of parasitic disease, comprises following component: Semen Armeniacae Amarum 38g, Chinese Tamarisk Twing 24g, Bin youth 9g, Semen Cucurbitae 16g.
Comparative example 2: a kind of Chinese medicine composition for the treatment of parasitic disease, comprises following component: Semen Armeniacae Amarum 38g, Chinese Tamarisk Twing 24g, Semen Arecae 9g, Realgar 5g.
Comparative example 3: a kind of Chinese medicine composition for the treatment of parasitic disease, comprises following component: Semen Armeniacae Amarum 38g, Chinese Tamarisk Twing 24g, Semen Cucurbitae 16g, Realgar 5g.
Comparative example 4: a kind of Chinese medicine composition for the treatment of parasitic disease, comprises following component: Semen Armeniacae Amarum 38g, Bin youth 9g, Semen Cucurbitae 16g, Realgar 5g.
Comparative example 5: a kind of Chinese medicine composition for the treatment of parasitic disease, comprises following component: Chinese Tamarisk Twing 24g, Semen Arecae 9g, Semen Cucurbitae 16g, Realgar 5g.
Wherein the preparation method of embodiment 1-4 and comparative example 1-5 includes following steps: get Semen Armeniacae Amarum in formula, Chinese Tamarisk Twing, Semen Arecae, Semen Cucurbitae, Realgar, after adding 10 times amount soak with ethanol 14-20 hours, add 12-16 times amount water boiling and extraction 3-5 time, each 0.5-1 hour, merge extractive liquid, filter, after concentrating under reduced pressure, concentrated solution adopts suitable quantity of water dilution, ultrafiltration, ultrafiltrate is concentrated into relatively for density is the thick paste of 1.20-1.45, drying under reduced pressure, obtained described Chinese medicine composition, adds customary adjuvant and prepares injection.
The Chinese medicine composition of the chronic parasitic disease for the treatment of of the present invention, clinical efficacy is summed up:
One, diagnostic criteria:
Criterion: the clinical manifestation disappearing according to the scurf of sick dog, dermatitis disappears, skin color recovers normal, grown gradually by hair and lab testing are assessed, and judge treatment situation.
Two, experiment grouping: the sick dog suffering from parasitic disease is divided into 6 groups at random, often organize 5, be respectively the embodiment of the present invention 1, comparative example 1-5 injection, administering mode is subcutaneous injection, every injection in 5 days once, is used in conjunction 3 times.
Three, criterion of therapeutical effect:
Recovery from illness: refer to that symptom all disappears, lab testing pathogen is negative or death;
Effective: transference cure is greater than 60%, lab testing pathogen is negative or mortality;
Take a turn for the better: refer to transference cure 20 ~ 60%, pathogen is positive;
Invalid: to refer to that transference cure is less than 20%, pathogenic examination is positive.
Recovery from illness, effective and improvement are referred to as effectively, effective percentage=(recovery from illness number+effective number+good revolution)/always number of animals × 100%.
Four, therapeutic effect: in this clinical observation case, injects 1-2 the course for the treatment of, and institute's curative effect that obtains is in table 1.
The effect of table 1. traditional Chinese medicine composition for treating parasitic disease
| Recovery from illness (example) | Recovery from illness (rate) | Effectively (example) | Effectively (rate) | Invalid (example) | Invalid (rate) | |
| Embodiment 1 | 5 | 100% | 5 | 100% | 0 | 0 |
| Comparative example 1 | 2 | 40% | 3 | 60% | 2 | 40% |
| Comparative example 2 | 2 | 40% | 2 | 40% | 3 | 60% |
| Comparative example 3 | 2 | 40% | 3 | 60% | 2 | 40% |
| Comparative example 4 | 2 | 40% | 2 | 40% | 3 | 60% |
| Comparative example 5 | 2 | 40% | 3 | 60% | 2 | 40% |
Experimental result shows: embodiment 1 and comparative example 1-5 all have certain therapeutic effect for parasitic disease, and cure rate can reach more than 40% respectively, and total effective rate can reach more than 40% respectively; But, the combination of Semen Armeniacae Amarum, Chinese Tamarisk Twing, Bin youth, Semen Cucurbitae, Realgar five kinds of Chinese medicine compositions in embodiment 1, make its therapeutic effect than only there being the therapeutic effect tool of the combination of compositions of four kinds of Chinese medicines to be significantly increased in comparative example 1-5, cure rate can reach 100%, and total effective rate can reach 100%.Visible, have the effect of Synergistic between Semen Armeniacae Amarum, Chinese Tamarisk Twing, Bin youth, Semen Cucurbitae, Realgar five kinds of medicines, lack wherein a herb arbitrarily, its curative effect all has obvious reduction, therefore complements each other between this Chinese medicine of the five flavours, indispensable.There is not toxic and side effects in treatments period.
Above embodiments of the invention have been described in detail, but described content being only preferred embodiment of the present invention, can not being considered to for limiting practical range of the present invention.All equalizations done according to the present patent application scope change and improve, and all should still belong within patent covering scope of the present invention.
Claims (8)
1. treat a Chinese medicine composition for parasitic disease, it is characterized in that, comprise the component of following weight portion: Semen Armeniacae Amarum 28-42 part, Chinese Tamarisk Twing 18-28 part, Bin youth 6-10 part, Semen Cucurbitae 14-18 part, Realgar 2-6 part.
2. a kind of Chinese medicine composition for the treatment of parasitic disease according to claim 1, is characterized in that, comprise the component of following weight portion: 28 parts, Semen Armeniacae Amarum, Chinese Tamarisk Twing 18 parts, Semen Arecae 6 parts, Semen Cucurbitae 14 parts, Realgar 2 parts.
3. a kind of Chinese medicine composition for the treatment of parasitic disease according to claim 1, is characterized in that, comprise the component of following weight portion: 42 parts, Semen Armeniacae Amarum, Chinese Tamarisk Twing 28 parts, Bin youth 10 parts, Semen Cucurbitae 18 parts, Realgar 6 parts.
4. a kind of Chinese medicine composition for the treatment of parasitic disease according to claim 1, is characterized in that, comprise the component of following weight portion: 34 parts, Semen Armeniacae Amarum, Chinese Tamarisk Twing 22 parts, Bin youth 7 parts, Semen Cucurbitae 16 parts, Realgar 4 parts.
5. a kind of Chinese medicine composition for the treatment of parasitic disease according to claim 1, is characterized in that, comprise the component of following weight portion: 38 parts, Semen Armeniacae Amarum, Chinese Tamarisk Twing 24 parts, Bin youth 9 parts, Semen Cucurbitae 16 parts, Realgar 5 parts.
6. prepare the method for Chinese medicine composition described in claim 1-5 for one kind, it is characterized in that, comprise the following steps: get Semen Armeniacae Amarum in formula, Chinese Tamarisk Twing, Bin youth, Semen Cucurbitae, Realgar, after adding 10 times amount soak with ethanol 14-20 hours, add 12-16 times amount water boiling and extraction 3-5 time, each 0.5-1 hour, merge extractive liquid, filter, after concentrating under reduced pressure, concentrated solution adopts suitable quantity of water dilution, ultrafiltration, and ultrafiltrate is concentrated into relatively for density is the thick paste of 1.20-1.45, drying under reduced pressure, obtained described Chinese medicine composition.
7. contain a preparation for Chinese medicine composition as claimed in claim 1, it is characterized in that, described preparation is powder, pill, tablet, capsule, granule or injection.
8. the application of Chinese medicine composition in preparation treatment parasitic disease medicine as claimed in claim 1.
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| CN201510180044.1A CN104825709A (en) | 2015-04-16 | 2015-04-16 | Traditional Chinese medicinal composition for treating parasitic diseases |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232850A (en) * | 2015-11-11 | 2016-01-13 | 郑州后羿制药有限公司 | Chinese herbal medicine fermentative extracting solution for preventing and controlling parasitic diseases of freshwater fish and preparation method thereof |
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| CN1090497A (en) * | 1993-02-06 | 1994-08-10 | 董昆仑 | Antiscolic and manufacture method |
| CN1569076A (en) * | 2003-07-21 | 2005-01-26 | 张键德 | Dermatosis treating medicine |
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2015
- 2015-04-16 CN CN201510180044.1A patent/CN104825709A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1090497A (en) * | 1993-02-06 | 1994-08-10 | 董昆仑 | Antiscolic and manufacture method |
| CN1569076A (en) * | 2003-07-21 | 2005-01-26 | 张键德 | Dermatosis treating medicine |
Non-Patent Citations (2)
| Title |
|---|
| 刘松林等: "《中医内科诊治要诀》", 31 May 2001, 山西科学技术出版社 * |
| 郭国华等: "《实用袖珍中药辞典 （第2版）》", 30 June 2006, 湖南科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232850A (en) * | 2015-11-11 | 2016-01-13 | 郑州后羿制药有限公司 | Chinese herbal medicine fermentative extracting solution for preventing and controlling parasitic diseases of freshwater fish and preparation method thereof |
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Effective date of registration: 20181224 Address after: 313000 1403, room 14, B building, free port, 1188 headquarters, Wuxing District, Huzhou, Zhejiang. Applicant after: Zhejiang creation Intellectual Property Service Co., Ltd. Address before: 313000 C509 2, No. 1236, long Wang Shan Road, Huzhou economic and Technological Development Zone, Zhejiang Applicant before: Huzhou Pin Chuan brooder company limited |
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Application publication date: 20150812 |