CN1840165A - Preparation method of pinellia-containing stomach-harmonizing Chinese proprietary medicine - Google Patents
Preparation method of pinellia-containing stomach-harmonizing Chinese proprietary medicine Download PDFInfo
- Publication number
- CN1840165A CN1840165A CN 200610018326 CN200610018326A CN1840165A CN 1840165 A CN1840165 A CN 1840165A CN 200610018326 CN200610018326 CN 200610018326 CN 200610018326 A CN200610018326 A CN 200610018326A CN 1840165 A CN1840165 A CN 1840165A
- Authority
- CN
- China
- Prior art keywords
- extract
- raw material
- rhizoma
- ethanol
- filter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention also relates to the process for preparing medicament for the treatment of stomach diseases, wherein the raw materials include pinellia tuber, dried ginger, pilose asiabell root, honey-fried licorice root, goldthread root, Chinese dates and baikal skullcap root.
Description
Technical field
The present invention relates to Chinese medicine, particularly the preparation method of Chinese medicine Rhizoma Pinelliae stomach function regulating.
Background technology
Chronic gastritis, peptic ulcer belong to categories such as traditional Chinese medical science gastric abscess, feeling of fullness, and main disease performance has gastralgia, feeling of distension and oppression feeling of fullness, singultus belch, noisy, the indigestion and loss of appetite lack of appetite of pantothenic acid, loose stool diarrhea etc., are common frdquently encountered disease clinically, and delay is difficult.
The tradition traditional Chinese medical science thinks that stomach belongs under the heart, and with spleen the exterior and the interior each other, stomach receiving food and drink, its gas master falls, and The spleen has the function to transport and transform nutrients, its gas master liter, and spleen rises stomach and falls, and middle burnt mechanism of qi is smooth and easy, and the fortuneization of becoming thoroughly decomposed often has, and then can exercise the foundation of acquired constitution.If cold due to wound wrong treatment, impairing the spleen and stomach, pathogenic heat are caved in; Or factor body deficiency of YANG of middle-JIAO loses weakness of the spleen and stomach; Eating and drinking without temperance in addition, work and rest mistake degree, feelings will is not relaxed, and phlegm-damp is stagnant, and damp and hot heresy is taken advantage of a weak point, and all can cause the spleen and stomach function disorder, imbalance of YIN and YANG, cold and heat are tied mutually, and then obstructed up and down, QI-blood circulation is not smooth, and stomach alkane pain, feeling of fullness disease are taken place.
Modern medicine infects the generation of chronic gastritis, peptic ulcer and is associated with helicobacter pylori, antimicrobial drug, antacid, the medicine for stomach dynamic etc. of adopting in the treatment more, or multi-joint medication, though reach curative effect preferably, but recurrence rate after healing height, and the course of disease is long again, and medicine time is long, produces various side effect unavoidablely.As: gastrointestinal upset, insomnia, giddy, headache etc.
This disease of Chinese medicine has its unique advantage: 1, do not exist toleration, the patient compliance of taking medicine good; 2, treating both the principal and secondary aspects of a disease, efficacy consolidation, relapse rate is low.As long as dialectical accurate, dispensing is suited the medicine to the illness, and often can receive comparatively ideal curative effect.
Rhizoma Pinelliae stomach function regulating prescription was become painful abdominal mass to establish by the typhoid fever erroneous administration of purgatives, the representative side that generally acknowledged this side of ancient Chinese medicine doctor is harmonizing intestine-stomach by the development of deriving of banxia xiexin decoction in the treatise on Febrile Diseases originally.Prescription is made up of Chinese medicines such as Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Radix Scutellariae, Rhizoma Coptidis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Fructus Jujubaes, wherein Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, hot temperature eliminating stagnation disappear painful abdominal mass, the spleen-cold syndrome of dispelling gas with and cloudy, Radix Scutellariae, Rhizoma Coptidis, bitter cold are fallen and are let out, the heat of the gastric qi that disappears with and the sun, four medicines are usefulness mutually, pungent drugs can disperse and bitter drugs can descend, negative and positive must with, taste must be transferred, and this beginning of curing tame pungent drugs can disperse and bitter drugs can descend method is done for the back.Help again with Radix Codonopsis, Radix Glycyrrhizae, Fructus Jujubae Radix Glycyrrhizae and go into taste, coordinating the actions of various ingredients in a prescription, air making-up and spleen enlivening is with solid the foundation of acquired constitution.Promptly close the purport of " interior warp " " healthy energy is deposited interior heresy and can not be done ".
In the last few years, scholar's research 100 flavor Chinese medicines were to the helicobacter pylori inhibitory action, and result of the test shows that Rhizoma Coptidis, Radix Scutellariae have " height bacteriostasis ", come 100 flavor medical materials last, two.Contain this two flavors medical material in the Rhizoma Pinelliae stomach function regulating prescription, for the treatment of chronic gastritis, peptic ulcer, separate in the Chinese medicine west, has feasibility in theory.
Though Rhizoma Pinelliae stomach function regulating prescription has good curative effect for treatment chronic gastritis and gastric ulcer, traditional instructions of taking is to take after decocting with water, and takes inconvenience, and the dose of medicament is big, and bitter, and compliance of patients is poor.
At present, the Chinese patent medicine that does not also have Rhizoma Pinelliae stomach function regulating on the market, its reason comprises that there are some difficulties in the preparation technology of the Chinese patent medicine of producing Rhizoma Pinelliae stomach function regulating, these difficulties comprise: 1, the difficulty to the extraction of the effective ingredient of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Rhizoma Coptidis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Fructus Jujubae and purification is big, can't fully extract the effective ingredient in the raw material, the cost height; 2, with traditional method all raw materials are mixed the back effective component extracting, can cause the forfeiture of Radix Scutellariae effective ingredient.
Summary of the invention
Technical problem to be solved by this invention is: a kind of preparation method of Rhizoma Pinelliae stomach function regulating Chinese patent medicine is provided, and this preparation method is simple, and product cost is low.
The present invention solves the problems of the technologies described above the technical scheme that is adopted:
The preparation method of Rhizoma Pinelliae stomach function regulating Chinese patent medicine, it comprises:
Obtain the step of extract I, the raw material of this step comprises Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Rhizoma Coptidis, Fructus Jujubae;
Obtain the step of extract II, the raw material of this step comprises Radix Scutellariae;
The step of Rhizoma Pinelliae stomach function regulating Chinese patent medicine will be made behind extract I and the extract II merging mixing.
In the such scheme, the step that obtains extract I comprises:
(1) with after the raw material mixing, decocts with water, filter, get filtrate;
(2) in filtrate, leave standstill behind the adding ethanol, separate slag, liquid, must contain ethanol liquid;
(3) reclaim the ethanol that contains in the ethanol liquid;
(4) remaining liq is concentrated into thick paste, gets extract I;
In the such scheme, step (1) is specially: after raw material is mixed, add the water of 2～15 times of raw material weights, decocted 0.5～5 hour, filter; In slag, add the water of 3～15 times of raw material weights, decocted 1～4 hour, filter; Merging filtrate.
In the such scheme, step (2) is specially: it is 1.05～1.50 that filtrate is concentrated into relative density, puts and is chilled to room temperature; Stir and slowly to add 50～100% ethanol down, make to contain the alcohol amount and reach 30～90%, left standstill 12～24 hours, filter; In filtering residue, add 30～90% washing with alcohol; Separate slag, liquid; Merging filtrate and cleaning mixture must contain ethanol liquid.
In the such scheme, the relative density of thick paste is 1.05～1.50.
In the such scheme, the step of making Rhizoma Pinelliae stomach function regulating Chinese patent medicine behind extract I and the extract II merging mixing is comprised:
(1) extract I and extract II are merged mixing;
(2) 40～80 ℃ of oven dry, obtain dry extract;
(3) dry extract is pulverized, crossed 60～80 mesh sieves;
(4) with 70%～90% ethanol as wetting agent, the system soft material is granulated, and makes Rhizoma Pinelliae stomach function regulating Chinese patent medicine.
In the such scheme, the step that obtains extract II is specially: raw material is mixed the water that adds 5～15 times of raw material weights, decocted 1～4 hour, filter; In slag, add the water of 3～10 times of raw material weights, decocted 1～3 hour, filter; Merging filtrate; It is 1.05～1.50 thick paste that filtrate is concentrated into relative density, extract II.
In the such scheme, the weight part ratio of each raw material is: Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 3.5～4.5, Radix Scutellariae 2.5～3.5, Rhizoma Zingiberis 2.5～3.5, Radix Codonopsis 2.5～3.5, Radix Glycyrrhizae Preparata 2.5～3.5, Rhizoma Coptidis 1, Fructus Jujubae 1.5～2.5.
The invention has the advantages that:
1, according to Material Characteristics, distinguish effective component extracting, extract the effective ingredient of Radix Scutellariae separately, again the effective ingredient that extracts is merged, be prepared into Rhizoma Pinelliae stomach function regulating Chinese patent medicine, can not cause the forfeiture of Radix Scutellariae effective ingredient, method is simple, and product cost is low.
2, to the extraction of the effective ingredient of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Rhizoma Coptidis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Fructus Jujubae, adopt earlier and extract, the method for back ethanol purification is fully extracted the effective ingredient in the raw material, and method is simple, and cost is low;
3, to the extraction of the effective ingredient of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Rhizoma Coptidis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Fructus Jujubae, adopt the method that decocts with water for twice, can fully extract the effective ingredient in the raw material;
4, to the extraction of the effective ingredient of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Rhizoma Coptidis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Fructus Jujubae, the method that adopts twice ethanol to purify is fully extracted the effective ingredient in the raw material;
The Rhizoma Pinelliae stomach function regulating Chinese patent medicine of the inventive method preparation has the effect of good anti-gastric-ulcer and treatment chronic gastritis.
1, to the inhibitory action of experimental gastric ulcer.
(1) to the inhibitory action of rat pyloric ligation ulcers gastric ulcer.
48 hours rat of fasting is implemented pylorus ligation, after 18 hours, can make the preceding stomach mucosa of rat form ulcer, ulcer is point-like or lamellar, and severe patient can cause perforation.Irritate stomach once every day before the Rhizoma Pinelliae stomach function regulating dry extract art, and continuous three days, during operation, more once by duodenal administration.The result shows: 10.0, and the Rhizoma Pinelliae stomach function regulating dry extract of 20.0g crude drug/kg can significantly suppress the formation of ulcer, and suppression ratio is respectively 51.5 and 66.7%.
(2) to the inhibitory action of rat gastric ulcer due to hydrochloric acid-ethanol,, irritate hydrochloric acid-ethanol (50%) 1.0ml/ Mus that stomach gives 0.15mol/L, after 4 hours, can make rat glandular stomach portion strip ulcer occur 36 hours rat of fasting.Before giving hydrochloric acid-ethanol, once a day, the suspension of irritating stomach Rhizoma Pinelliae stomach function regulating dry extract in continuous four days can significantly suppress the formation of ulcer, and 10.0, the suppression ratio of the Rhizoma Pinelliae stomach function regulating dry extract of 20.0g crude drug/kg is respectively 37.4% and 87.0%.
2, clinical research
To chronic superficial gastritis, the effective percentage of Rhizoma Pinelliae stomach function regulating Chinese patent medicine is 98.8%.
The inventive method is extracted, is made with extra care Rhizoma Pinelliae stomach function regulating tradition prescription, and Rhizoma Pinelliae stomach function regulating Chinese patent medicine curative effect is reliable, safety and stability, and taking convenience is convenient to transportation and is carried.
The specific embodiment
The preparation method embodiment 1 of Rhizoma Pinelliae stomach function regulating Chinese patent medicine of the present invention, the product of this embodiment are Rhizoma Pinelliae stomach function regulating granule, and its concrete steps are:
1, gets raw material Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 400g, Radix Scutellariae 300g, Rhizoma Zingiberis 300g, Radix Codonopsis 300g, Radix Glycyrrhizae Preparata 300g, Rhizoma Coptidis 100g, Fructus Jujubae 200g.
2, obtain the step of extract I, the raw material of this step comprises Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Rhizoma Coptidis, Fructus Jujubae, and the weight of raw material is 1.6kg; Be specially:
(1) with after the raw material mixing, decocts with water, filter, get filtrate; Be specially:
After the raw material mixing, add the water of raw material weight 8 times (12.8kg), decocted 2 hours, filter; In slag, add the water of raw material weight 8 times (12.8kg), decocted 2 hours, filter; Merging filtrate.
(2) in filtrate, leave standstill behind the adding ethanol, separate slag, liquid, must contain ethanol liquid; Be specially:
It is 1.25 that filtrate is concentrated into relative density, puts and is chilled to room temperature; Stir down and slowly add 90% ethanol, make to contain the alcohol amount and reach 60%, left standstill 20 hours, filter; In filtering residue, add 60% washing with alcohol; Separate slag, liquid; Merging filtrate and cleaning mixture must contain ethanol liquid.
(3) reclaim the ethanol that contains in the ethanol liquid;
(4) remaining liq is concentrated into thick paste, the relative density of thick paste is 1.25, gets extract I;
3, obtain the step of extract II, the raw material of this step is the 300g Radix Scutellariae; Be specially:
Raw material is mixed the water that adds raw material weight 8 times (2.4kg), decocted 2 hours, filter; In slag, add the water of raw material weight 8 times (2.4kg), decocted 2 hours, filter; Merging filtrate; It is 1.25 thick paste that filtrate is concentrated into relative density, extract II.
4, will make the particulate step of Chinese patent medicine Rhizoma Pinelliae stomach function regulating behind extract I and the extract II merging mixing, be specially:
(1) extract I and extract II are merged mixing;
(2) in oven dry below 80 ℃, obtain dry extract;
(3) dry extract is pulverized, crossed 60～80 mesh sieves, with the flavouring agent mixing; The weight of flavouring agent is 1～5 times of dry extract weight.Flavouring agent comprises cane sugar powder, dextrin, steviosin, aspartame.
(4) with 70%～90% ethanol as wetting agent, the system soft material, 12～14 mesh sieves are granulated, and promptly get Chinese patent medicine Rhizoma Pinelliae stomach function regulating granule, are divided into 100 collation packages.
Instructions of taking is: every day 3 times, each bag.
The preparation method embodiment 2 of Rhizoma Pinelliae stomach function regulating Chinese patent medicine of the present invention, the product of this embodiment are the Rhizoma Pinelliae and capsule for treating gastropathy, and its concrete steps are:
1, gets raw material Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 350g, Radix Scutellariae 250g, Rhizoma Zingiberis 250g, Radix Codonopsis 250g, Radix Glycyrrhizae Preparata 250g, Rhizoma Coptidis 100g, Fructus Jujubae 250g.
2, obtain the step of extract I, the raw material of this step comprises that Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Rhizoma Coptidis, Fructus Jujubae raw material weight are 1.45kg; Be specially:
(1) with after the raw material mixing, decocts with water, filter, get filtrate; Be specially:
After the raw material mixing, add the water of raw material weight 2 times (2.9kg), decocted 0.5 hour, filter; In slag, add the water of raw material weight 3 times (4.35kg), decocted 1 hour, filter; Merging filtrate.
(2) in filtrate, leave standstill behind the adding ethanol, separate slag, liquid, must contain ethanol liquid; Be specially:
It is 1.05 that filtrate is concentrated into relative density, puts and is chilled to room temperature; Stir down and slowly add 50% ethanol, make to contain the alcohol amount and reach 30%, left standstill 24 hours, filter; In filtering residue, add 30% washing with alcohol; Separate slag, liquid; Merging filtrate and cleaning mixture must contain ethanol liquid.
(3) reclaim the ethanol that contains in the ethanol liquid;
(4) remaining liq is concentrated into thick paste, the relative density of thick paste is 1.05, gets extract I;
3, obtain the step of extract II, the raw material of this step is the 250g Radix Scutellariae; Be specially:
Raw material is mixed the water that adds raw material weight 5 times (1.25kg), decocted 1 hour, filter; In slag, add the water of raw material weight 3 times (0.75kg), decocted 1 hour, filter; Merging filtrate; It is 1.05 thick paste that filtrate is concentrated into relative density, extract II.
4, will make the capsular step of Chinese patent medicine Rhizoma Pinelliae stomach function regulating behind extract I and the extract II merging mixing, be specially:
(1) extract I and extract II are merged mixing;
(2) in oven dry below 60 ℃, obtain dry extract;
(3) dry extract is pulverized, crossed 60～80 mesh sieves;
(4) with 70%～90% ethanol as wetting agent, the system soft material, 40 mesh sieves are granulated, the fill capsule promptly gets 500～800 of the Chinese patent medicine Rhizoma Pinelliae and capsule for treating gastropathy.
Instructions of taking is: every day 3 times, each 5～8.
The preparation method embodiment 3 of Rhizoma Pinelliae stomach function regulating Chinese patent medicine of the present invention, the product of this embodiment are Rhizoma Pinelliae stomach function regulating sheet, and its concrete steps are:
1, gets raw material Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 450g, Radix Scutellariae 350g, Rhizoma Zingiberis 350g, Radix Codonopsis 350g, Radix Glycyrrhizae Preparata 350g, Rhizoma Coptidis 100g, Fructus Jujubae 150g.
2, obtain the step of extract I, the raw material of this step comprises that Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Rhizoma Coptidis, Fructus Jujubae raw material weight are 1.25kg; Be specially:
(1) with after the raw material mixing, decocts with water, filter, get filtrate; Be specially:
After the raw material mixing, add the water of raw material weight 15 times (18.75kg), decocted 5 hours, filter; In slag, add the water of raw material weight 15 times (18.75kg), decocted 4 hours, filter; Merging filtrate.
(2) in filtrate, leave standstill behind the adding ethanol, separate slag, liquid, must contain ethanol liquid; Be specially:
It is 1.50 that filtrate is concentrated into relative density, puts and is chilled to room temperature; Stir down and slowly add 100% ethanol, make to contain the alcohol amount and reach 90%, left standstill 12 hours, filter; In filtering residue, add 90% washing with alcohol; Separate slag, liquid; Merging filtrate and cleaning mixture must contain ethanol liquid.
(3) reclaim the ethanol that contains in the ethanol liquid;
(4) remaining liq is concentrated into thick paste, the relative density of thick paste is 1.50, gets extract I;
3, obtain the step of extract II, the raw material of this step comprises the 350g Radix Scutellariae; Be specially:
Raw material is mixed the water that adds raw material weight 15 times (5.25kg), decocted 4 hours, filter; In slag, add the water of raw material weight 10 times (3.5kg), decocted 3 hours, filter; Merging filtrate; It is 1.50 thick paste that filtrate is concentrated into relative density, extract II.
4, will make the step of Rhizoma Pinelliae stomach function regulating Chinese patent medicine behind extract I and the extract II merging mixing, be specially:
(1) extract I and extract II are merged mixing;
(2) in oven dry below 40 ℃, obtain dry extract;
(3) dry extract is pulverized, crossed 60～80 mesh sieves;
(4) add adjuvant mix homogeneously such as CMC-Na; As wetting agent, make soft material with 70%～90% ethanol, 40 mesh sieves are granulated, and tabletting, coating promptly get 500～800 in Chinese patent medicine Rhizoma Pinelliae stomach function regulating tablet.
Instructions of taking is: every day 3 times, each 5～8.
Claims (8)
1, the preparation method of Rhizoma Pinelliae stomach function regulating Chinese patent medicine, it is characterized in that: it comprises:
Obtain the step of extract I, the raw material of this step comprises Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Zingiberis, Radix Codonopsis, Radix Glycyrrhizae Preparata, Rhizoma Coptidis, Fructus Jujubae;
Obtain the step of extract II, the raw material of this step comprises Radix Scutellariae;
The step of Rhizoma Pinelliae stomach function regulating Chinese patent medicine will be made behind extract I and the extract II merging mixing.
2, the method for claim 1 is characterized in that: the step that obtains extract I comprises:
(1) with after the raw material mixing, decocts with water, filter, get filtrate;
(2) in filtrate, leave standstill behind the adding ethanol, separate slag, liquid, must contain ethanol liquid;
(3) reclaim the ethanol that contains in the ethanol liquid;
(4) remaining liq is concentrated into thick paste, gets extract I;
3, method as claimed in claim 2 is characterized in that: step (1) is specially: after raw material is mixed, add the water of 2～15 times of raw material weights, decocted 0.5～5 hour, filter; In slag, add the water of 3～15 times of raw material weights, decocted 1～4 hour, filter; Merging filtrate.
4, method as claimed in claim 2 is characterized in that: step (2) is specially: it is 1.05～1.50 that filtrate is concentrated into relative density, puts and is chilled to room temperature; Stir and slowly to add 50～100% ethanol down, make to contain the alcohol amount and reach 30～90%, left standstill 12～24 hours, filter; In filtering residue, add 30～90% washing with alcohol; Separate slag, liquid; Merging filtrate and cleaning mixture must contain ethanol liquid.
5, method as claimed in claim 2 is characterized in that: the relative density of thick paste is 1.05～1.50.
6, the method for claim 1 is characterized in that: the step of making Rhizoma Pinelliae stomach function regulating Chinese patent medicine behind extract I and the extract II merging mixing is comprised:
(1) extract I and extract II are merged mixing;
(2) 40～80 ℃ of oven dry, obtain dry extract;
(3) dry extract is pulverized, crossed 60～80 mesh sieves;
(4) with 70%～90% ethanol as wetting agent, the system soft material is granulated, and makes Rhizoma Pinelliae stomach function regulating Chinese patent medicine.
7, the method for claim 1 is characterized in that: the step that obtains extract II is specially: raw material is mixed the water that adds 5～15 times of raw material weights, decocted 1～4 hour, filter; In slag, add the water of 3～10 times of raw material weights, decocted 1～3 hour, filter; Merging filtrate; It is 1.05～1.50 thick paste that filtrate is concentrated into relative density, extract II.
8, the method for claim 1 is characterized in that: the weight part ratio of each raw material is: Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 3.5～4.5, Radix Scutellariae 2.5～3.5, Rhizoma Zingiberis 2.5～3.5, Radix Codonopsis 2.5～3.5, Radix Glycyrrhizae Preparata 2.5～3.5, Rhizoma Coptidis 1, Fructus Jujubae 1.5～2.5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610018326 CN1840165A (en) | 2006-01-28 | 2006-01-28 | Preparation method of pinellia-containing stomach-harmonizing Chinese proprietary medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610018326 CN1840165A (en) | 2006-01-28 | 2006-01-28 | Preparation method of pinellia-containing stomach-harmonizing Chinese proprietary medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1840165A true CN1840165A (en) | 2006-10-04 |
Family
ID=37029469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610018326 Pending CN1840165A (en) | 2006-01-28 | 2006-01-28 | Preparation method of pinellia-containing stomach-harmonizing Chinese proprietary medicine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1840165A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101780263A (en) * | 2010-03-25 | 2010-07-21 | 江苏济川制药有限公司 | Traditional Chinese medicine composition for treating chronic gastritis and preparation method thereof |
| CN103479977A (en) * | 2013-08-29 | 2014-01-01 | 武汉福星生物药业有限公司 | Novel preparation method for pinellia stomach-harmonizing Chinese patent medicine |
| CN104146963B (en) * | 2014-08-06 | 2017-08-15 | 南京朗尼医药科技有限公司 | A kind of banxia xiexin decoction sugar-free type granular formulation and preparation method thereof |
| CN111166858A (en) * | 2019-12-05 | 2020-05-19 | 沈阳药科大学 | Preparation method of stomach harmonizing granules |
| CN111888416A (en) * | 2020-09-22 | 2020-11-06 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating chronic non-atrophic gastritis and application thereof |
-
2006
- 2006-01-28 CN CN 200610018326 patent/CN1840165A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101780263A (en) * | 2010-03-25 | 2010-07-21 | 江苏济川制药有限公司 | Traditional Chinese medicine composition for treating chronic gastritis and preparation method thereof |
| CN103479977A (en) * | 2013-08-29 | 2014-01-01 | 武汉福星生物药业有限公司 | Novel preparation method for pinellia stomach-harmonizing Chinese patent medicine |
| CN103479977B (en) * | 2013-08-29 | 2014-09-17 | 武汉福星生物药业有限公司 | Novel preparation method for pinellia stomach-harmonizing Chinese patent medicine |
| CN104146963B (en) * | 2014-08-06 | 2017-08-15 | 南京朗尼医药科技有限公司 | A kind of banxia xiexin decoction sugar-free type granular formulation and preparation method thereof |
| CN111166858A (en) * | 2019-12-05 | 2020-05-19 | 沈阳药科大学 | Preparation method of stomach harmonizing granules |
| CN111888416A (en) * | 2020-09-22 | 2020-11-06 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating chronic non-atrophic gastritis and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1739783A (en) | Chinese medicine composition for treating gastritis, gastric ulcer and duodenal ulcer | |
| CN1833688A (en) | Medicine for treating gastro-duodenal ulcer and chronic gastritis and its prepn. | |
| CN1295973C (en) | Fat-reducing health tea | |
| CN1943773A (en) | A Chinese traditional medicinal composition and its preparation methods | |
| CN102716416A (en) | Traditional Chinese medicine composition for treating stomach diseases | |
| CN1895573A (en) | Medicinal composition for treating oral exulceratio, its preparation and use | |
| CN1840165A (en) | Preparation method of pinellia-containing stomach-harmonizing Chinese proprietary medicine | |
| CN1535625A (en) | Stomach-fortifying beverage and its preparation method | |
| CN104474386A (en) | Traditional Chinese medicine composition for treating reflux esophagitis | |
| CN104001131B (en) | A kind of Chinese medicine for oral administration preventing and treating stress ulcer | |
| CN1168475C (en) | Chinese herbal medicine composition for treating pyloric spirobacterium infected gastropathy and its production process | |
| CN102940844B (en) | Medicine composition for treating dyspepsia | |
| CN101028488A (en) | Chinese medicine for chronic pharyngitis, esophagus inflammation and esophagus cancer | |
| CN101985022B (en) | Chinese medicinal composition for treating damp heat enteritis | |
| CN104258359A (en) | Traditional Chinese medicine combination for curing pregnancy reaction and preparation method of preparations thereof | |
| CN103784665B (en) | Alleviate Chinese medicine preparation of irritable bowel syndrome and preparation method thereof | |
| CN1706467A (en) | Plaster for treating bronchitis | |
| CN103860844B (en) | A kind of Chinese medicine preparation for the treatment of chronic colitis and preparation method thereof | |
| CN105687474A (en) | Preparation for cancer patient to take during chemotherapy period and preparation method | |
| CN1879598A (en) | Components of Chinese herbal facial mask for beauty treatment and method for preparing same | |
| CN105233233A (en) | Traditional Chinese medicine compound treating chronic gastric ulcers and preparation method thereof | |
| CN104491598A (en) | Traditional Chinese medicine composition for treating herpes zoster | |
| CN104524356A (en) | Traditional Chinese medicine composition for treating reflux esophagitis | |
| CN103784924A (en) | Anti-diarrhea Chinese medicinal composition and preparation method thereof | |
| CN1465357A (en) | Chinese patent drug for treating chronic gastritis and chronic gastric ulcer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |