CN109010246A - A kind of cosmetics of composition and oil-control water weighing apparatus - Google Patents
A kind of cosmetics of composition and oil-control water weighing apparatus Download PDFInfo
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- CN109010246A CN109010246A CN201811100563.2A CN201811100563A CN109010246A CN 109010246 A CN109010246 A CN 109010246A CN 201811100563 A CN201811100563 A CN 201811100563A CN 109010246 A CN109010246 A CN 109010246A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The present invention relates to the cosmetics that cosmetic technical field more particularly to a kind of composition (cool-fermex) and oil-control water weigh.In composition provided by the invention, it include: grape fruit extract, Flos Bombacis Malabarici extract, glycosylglycerol, the ocean matt factor and glycylglycine compounding, the composition of formation can have good control skin oil and fat content, improve skin moisture content, the effect for inhibiting moisture of skin lost.In composition, each component is indispensable, cooperates and generates the effect of synergy collaboration, and under suitable proportion, the effect of composition reaches best.
Description
Technical field
It weighs the present invention relates to cosmetic technical field more particularly to a kind of composition (cool-fermex) and oil-control water
Cosmetics.
Background technique
As the improvement of people's living standards, the transformation of people's social values, male's skin care is in China or even world wide
It is interior more and more common.Cosmetics have no longer been all one's efforts of woman, and male cosmetic market starts to move to maturity.Male cosmetic
Sales growth has benefited from the sustainable growth of emerging market sale.In China, man's fashion is not any news already, and man likes to be beautiful
It is beautiful also usual again but to show there is 39% male to will use cosmetics according to an external market tune difference, at home, this
A ratio will not be many less, and the growth that meets of male's skin care Chinese market in recent years is up to 29%.
Cosmetic formulations teacher needs to consider men and women's skin variations, needs according to ethnic group, the colour of skin, age, gender and skin
Difference of sensibility etc. is because being usually the market preparation skin care articles in the whole world.Male's skin and female skin no matter in appearance or
To there is huge difference in the reaction of the products such as anti-aging, male's skin has thicker cuticula compared with women, relative to female
For property skin, the ability for resisting external environment is strong, insensitive.But also therefore, the absorbability of male's skin is relatively weak.
From physiology level, between the sexes there should be a prudent reserve is embodied in skin quality conveniently first, and pore is more coarse in most of man's difficulty, grease
It secretes more, leads to pachylosis, acne, the indecency appearance such as dark sore and acne rosacea.And operating pressure, nervous and sleep is not
The problems such as multiple city syndromes with man such as foot also result in cutis laxa, dark and gloomy unglazed.The skin of man is partially oily
Property, and feminine care wind you be all moist type mostly, man is not used.Pure is simply the principle of man's skin care, with
When keep salubrious clean unimpeded with pore, make skin secretion normal, separate skin problem.
The water and oil balance for how ensuring skin, while controlling fat secretion, it is ensured that man's skin nourishes, and does not block hair
Hole, it is skin problem that this field needs to solve that pore is careful.
Summary of the invention
In view of this, the technical problem to be solved in the present invention is that provide the cosmetics of a kind of composition and oil-control water weighing apparatus,
The composition can control skin oil and fat content, improve skin moisture content, and moisture of skin is inhibited to scatter and disappear.
Composition provided by the invention is grouped as by the group of following mass parts:
In the embodiment of the present invention, the mass parts of each component in composition are as follows:
In the embodiment of the present invention, the mass parts of each component in composition are as follows:
In the embodiment of the present invention, the mass parts of each component in composition are as follows:
Grape fruit extract is extracted by the fruit of grape fruit (Citrus paradisi, also known as grapefruit) and is obtained, mainly
Ingredient is aurantiamarin, has anti-oxidant, anti-inflammatory, antibacterial, absorbs ultraviolet light and anti-allergic effects
Flos Bombacis Malabarici extract is extracted by the flower of Bombacaceae plant kapok and is obtained, and main component is oligosaccharide, can effectively be subtracted
Few husking, inhibits sebum to generate, and it is glossy to reduce skin for compact pore.
Glycosylglycerol (Glucosylglycerol, GG) be it is a kind of by glycerol and glucose molecule with glycosidic bond in conjunction with
Substance, have moisturizing, anti-oxidation function.
The ocean matt factor (matmarine) is to replace the born of the same parents that unicellular strain obtains from ocean vacation by biotechnology
Outer polymer, can reduce MC5-R (with sebaceous differentiation in relation to) protein level；Reduce accumulation and the sebum of sebum lipid
The maturation of gland cell；Inducing type I collagen synthesis reduces lipid peroxidation, reduces the expression of inflammation-related gene, increase with
The expression of anti-oxidant related gene.
Glycylglycine (Glycylglycine also known as L-Glycylglycine), can make white Jie of keratinocyte caused by oleic acid
The increase of plain 1L-1 α is inhibited, can intracellular ion caused by stabilizing unsaturated fatty acid it is unbalance, to make inflammatory
Cell factor generation is inhibited, and can not only reduce the structure that pore expands outwardly, while can also improve the skin around pore
State.
The present invention answers grape fruit extract, Flos Bombacis Malabarici extract, glycosylglycerol, the ocean matt factor and glycylglycine
Match, the composition of formation there can be good control skin oil and fat content, improve skin moisture content, and moisture of skin is inhibited to dissipate
The effect of mistake.In composition, each component is indispensable, cooperates and generates the effect of synergy collaboration, under suitable proportion, group
The effect of closing object reaches best.
In some embodiments, composition of the present invention further include: glycerol, propylene glycol, butanediol, oligomerization hyaluronic acid
Sodium, niacinamide, inositol and allantoin.
Glycerol, propylene glycol, butanediol, oligomerization Sodium Hyaluronate, niacinamide, inositol and the further Assisted Combinatorial of allantoin
Object plays effect, improves function of the composition in terms of moisturizing, moisturizing and oil-control.The composition is named as cool-fermex.
In these embodiments, in composition of the present invention, the mass parts of each component are as follows:
In some specific embodiments, the mass parts of each component in the composition are as follows:
In some specific embodiments, the mass parts of each component in the composition are as follows:
In some specific embodiments, the mass parts of each component in the composition are as follows:
Composition provided by the invention inhibits skin oil and fat content, raising skin moisture content in preparation, inhibits skin water
Disperse the application in the cosmetics lost.
Experiments verify that composition provided by the invention, to the facial area T fat content increase be suppressed to 442.09%~
501.18%, have the function of preferably to control fat secretion.It is 4.37%~7.28% to the inhibiting rate that moisture of skin scatters and disappears, says
Bright the composition has preferable reparation skin barrier ability.To the increasing action of skin moisture content up to 14.7%~
33.39%, illustrate that the composition has the preferable ability for promoting skin moisture content.Composition of the present invention is preferably
Man uses, so can be added into male cosmetic.
The present invention also provides a kind of cosmetics comprising composition of the present invention.
In cosmetics of the present invention:
The mass fraction of the composition is 0.19%~6.35%；Or the mass fraction of composition be 9.45%~
15.76%.
The cosmetics are mildy wash, toner, lotion, essence, facial mask, face cream, shampoo or bath oil.The makeup
Product are male cosmetic.
The present invention also provides a kind of facial masks comprising mask matrix and facial mask liquid；
The group of the following mass fraction of facial mask liquid is grouped as:
The preservative is PHL.
The preparation method of facial mask liquid of the present invention, comprising:
By water, glycerol, propylene glycol, butanediol, oligomerization Sodium Hyaluronate, niacinamide, inositol, allantoin, glycosylglycerol
Mixing is heated to 75 DEG C~80 DEG C, and 300r/min~400r/min stirs 30min；
55 DEG C~60 DEG C are cooled to, grape fruit extract, Flos Bombacis Malabarici extract and the ocean matt factor, 200r/min is added
~300r/min stirs 15min；
45 DEG C~50 DEG C are cooled to, glycylglycine and preservative is added, 200r/min~300r/min stirs 30min, cold
But room temperature is arrived, facial mask liquid is made.
In composition provided by the invention, comprising: grape fruit extract, Flos Bombacis Malabarici extract, glycosylglycerol, ocean are sub-
Light factor and glycylglycine compounding, the composition of formation can have good control skin oil and fat content, improve moisture of skin
Content, the effect for inhibiting moisture of skin lost.In composition, each component is indispensable, cooperates and generates the work of synergy collaboration
With under suitable proportion, the effect of composition reaches best.
Detailed description of the invention
Fig. 1 shows the face's area T fat content increment of each sample；
Fig. 2 shows the lost reduction amount of the moisture of skin of each sample；
Fig. 3 shows the skin moisture content incrementss of each sample.
Specific embodiment
The present invention provides the cosmetics that a kind of composition (cool-fermex) and oil-control water weigh, those skilled in the art
Present disclosure can be used for reference, realization of process parameters is suitably modified.In particular, it should be pointed out that all similar substitutions and modifications pair
It is it will be apparent that they are considered as being included in the present invention for those skilled in the art.Method and application of the invention is
Through being described by preferred embodiment, related personnel obviously can not depart from the content of present invention, in spirit and scope to this
The methods and applications of text are modified or appropriate changes and combinations, carry out implementation and application the technology of the present invention.
The test material that the present invention uses is all common commercially available product, can all be bought in market.
Below with reference to embodiment, the present invention is further explained:
Embodiment
Each group of formula such as table 1:
1 each group of formula (wt%) of table
Deionized water, glycerol, propylene glycol, butanediol, oligomerization Sodium Hyaluronate, niacinamide, inositol, urine are weighed according to the proportion
Bursin, glycosylglycerol are heated to 75~80 DEG C, with 300r/min~400r/min, stir 30min, dissolve to all substances
It is transparent；
55~60 DEG C are cooled the temperature to, grape fruit extract, Flos Bombacis Malabarici extract, ocean matt factor set are separately added into
Point, with 200~300r/min, stir 15 minutes；
Temperature is reduced to 45~50 DEG C, glycylglycine and preservative PHL is added, 30min is stirred with 200-300r/min,
It is cooled to room temperature and facial mask liquid is made.
Effect evaluation and test
1 oil-control efficacy assessments
1.1 test philosophy
This patent carries out the function of oil-Absorbing Sheets using effect using the skin oil and fat tester Sebumeter SM815 of Germany CK
Effect evaluation.Oil content test is using universally acknowledged SEBUMETER method, it is based on photometer principle, and a kind of 0.1mm is thick
After special delustring adhesive tape absorbs grease on human skin, a kind of translucent adhesive tape just will become, its light transmission capacity will be sent out
The grease of changing, absorption is more, and light transmission capacity will be bigger, can thus measure the content of skin oil and fat.It is maximum excellent
Point is that test probe size is small, easy to use, can test any position of skin.This is a kind of indirect survey of grease glandular secretion object
As a result amount method can be used to distinguish different skin types, make accurately to understand the grease as caused by inside and outside reason
Variation is possibly realized.
1.2 test method
This patent this time tests 21 test objects of selection, and 3 one group of people are divided into 7 groups, respectively forehead draw 3 having a size of
The region 3cm × 3cm carries out the evaluation and test of skin oil and fat content for blank sample (not wipe samples), control sample and patent sample respectively, often
A control sample takes the three related judges of value calculating fat content increment percentage progress for each person.
(1) the test object skin health selected, the age 18-30 years old, object was known after tested, was agreed to, study subject is clean
Behind face 15 minutes, its forehead fat content is measured as initial value.
(2) sample is not smeared in subject's forehead blank area, control sample area, patent sample area weigh 0.5ml Essence with 3cm
After × 3cm non-woven membrane cloth infiltrates cover skin 20min, non-woven fabrics is removed, waits for quietly 10 minutes, is carried out respectively for three regions
Fat content measurement, every 30min test is primary, persistently evaluates and tests 2h；
(3) environment is tested: T=25 DEG C of environment temperature of test, humidity H=50；
(4) testing time: carrying out face cleaning before testing, tests initial fat content within 15 minutes, tests 30min respectively,
60min, 90min, 120min test grease content data；
(5) test position: forehead marks blank, control sample, the test zone of patent sample.
1.3 effect evaluation results
2 fat content increment (%) of table
As shown in Table 2: being evaluated and tested by 3 hours, use the increasing of three of example sample 1~3 of the invention tested group greases
Long amount is 256.52%~331.82%, and relatively each control sample, the fat content using the subject of example sample is lower, illustrates reality
The suppression oil significant effect of example sample 1~3 is better than each control sample (p < 0.05), compared with example sample 3, extract dosage comparable 3
There are statistical difference (p < 0.05) with example sample 3 for suppression oil effect in control (control sample 2~4).Wherein, the suppression of example sample 3
Oily effect also conspicuousness be better than other each example samples, there are statistical significance, p < 0.05 for the effect.As a result illustrate, the application
The significant effect of the composition of offer is better than lacking constituent part or each group distribution ratio improperly sample.
2 percutaneous moisture loss evaluations
2.1 test philosophy
The measuring principle of the test apparatus derives from FICK Fick's law of diffusion: dm/dt=D.A.dp/dx.Pass through two groups
Temperature-humidity sensor measures the water vapor pressure ladder that nearly epidermis (about in 1cm) is formed by cuticula moisture loss in different bright spots
Degree, directly measures the amount of moisture percutaneously distributed.TEWL value is an important symbol of skin barrier quality, and the TEWL value of skin is got over
It is low, illustrate that the barrier function of skin is better, on the contrary it is poorer.
(2) experimental condition and volunteer require
Test environment conditions: test environment temperature is 22 ± 1 DEG C, and humidity is 50 ± 5%, and carries out dynamic in real time and examine
It surveys；
Volunteer requires: effective volunteer at least 30 people, age male between 16-65 years old: forearm test zone capacitor
Method moisture of skin measures the basic value of meaning between 15-100: without serious systemic disease, no immune deficiency or autoimmune
Disease patient；No active anaphylactic disease person；Previously to skin-care cosmetics without severe allergy history person；It was not used in nearly one month
Hormone medicine and immunosuppressor person: to participate in other clinical test persons；Use according to regulations test medicine and all information；It surveys
All volunteers should fill in informed consent form before trying；
(3) prepare before test
Any product (cosmetics or topical drug) cannot be used within 2-3 days before recipient site.Before experiment, subject needs same
It is surveyed in meaning cleaning both hands forearm, with dry face tissue wiped clean.It is surveyed in subject's both hands forearm after cleaning and carries out measured zone
Label.At least 30min that sits quietly in room should be being complied with standard before official testing, cannot drunk water, forearm exposure is put in test mode
It sets, keeps loosening.
(4) testing procedure
3 × 3cm of label on the inside of left and right arm in experiment2Test area, same arm can mark multiple regions, interregional
Every 1cm.Test product and blank control are randomly dispersed in left and right arm.Tested area is carried out using capacitance method skin analyzer
The measurement in domain and control zone.Each region is according to parallel determination 15 times.The plain pape for first measuring each test zone, is then pressed
2.0 ± 0.1mg sample/cm2Dosage, test is spread evenly across in trial zone using latex finger cot.Smearing measures 1,2 respectively
Hour, 4 hours, the moisture content of skin (being measured when verifying by this time) in tested region and blank control region, the same aspiration
The test of person is completed by the same survey crew.
Measure the TEWL value of day part respectively by experimental design, the lost reduction calculation formula of moisture of skin is as follows:
T%=(T0-T1)/T0 × 100%
T%: moisture of skin, which scatters and disappears, reduces percentage；
T0: moisture of skin windage before product is used；
T1: moisture of skin windage after product is used；
2.2 test result
Measure the TEWL value of day part respectively by experimental design.
3 moisture of skin of table scatters and disappears reduction amount
Note: negative value is represented in table increases relative to T0 moisture of skin windage；
Positive value is represented to be reduced relative to T0 moisture of skin windage.
As the result is shown: prescription of the present invention is evaluated and tested, tested group of moisture loss of example sample 1~3 by moisture of skin rate of scattering and disappearing
Reduction amount is 7.55%~10.78%, the inhibitory effect of relatively each control sample, the better effect of each example sample, p < 0.05, with reality
Example sample 3 is compared, and there is also statistics with example sample 3 for the moistening effect in comparable 3 controls (control sample 2~4) of extract dosage
It learns difference (p < 0.05).Wherein, the moistening effect of example sample 3 also conspicuousness be better than other each example samples, the effect exist system
Meter learns meaning, p < 0.05.As a result illustrate, the moistening effect of composition provided by the present application be significantly better than lack constituent part or
Each group distribution ratio improperly sample.
3 skin moisture content MMV test methods
3.1 test philosophy
For the method using the moisture content of capacitance method test human body keratoderma, its principle is based on water and other objects
The difference in dielectric constant of matter is significant, and according to moisture content of skin difference, the capacitance for measuring skin is different, and observed parameter can represent
Skin moisture value.
Test equipment:
German CK company Multi-functional skin tester, model C UTOMETER DUAL MPA580, this patent select skin water
Content measuring probe and the lost TEWL test of moisture of skin is divided to pop one's head in.
3.2 experimental conditions and volunteer require
Test environment conditions: test environment temperature is 22 ± 1 DEG C, and humidity is 50 ± 5%, and carries out dynamic in real time and examine
It surveys；
Volunteer requires: effective volunteer at least 30 people, age male between 16-65 years old: forearm test zone capacitor
Method moisture of skin measures the basic value of meaning between 15-100: without serious systemic disease, no immune deficiency or autoimmune
Disease patient；No active anaphylactic disease person；Previously to skin-care cosmetics without severe allergy history person；It was not used in nearly one month
Hormone medicine and immunosuppressor person: to participate in other clinical test persons；Use according to regulations test medicine and all information；It surveys
All volunteers should fill in informed consent form before trying；
Prepare before 3.3 tests
Any product (cosmetics or topical drug) cannot be used within 2-3 days before recipient site.Before experiment, subject needs same
It is surveyed in meaning cleaning both hands forearm, with dry face tissue wiped clean.It is surveyed in subject's both hands forearm after cleaning and carries out measured zone
Label.At least 30min that sits quietly in room should be being complied with standard before official testing, cannot drunk water, forearm exposure is put in test mode
It sets, keeps loosening.
3.4 testing procedure
3 × 3cm of label on the inside of left and right arm in experiment2Test area, same arm can mark multiple regions, interregional
Every 1cm.Test product and blank control are randomly dispersed in left and right arm.Tested area is carried out using capacitance method skin analyzer
The measurement in domain and control zone.Each region is according to parallel determination 15 times.The plain pape for first measuring each test zone, is then pressed
2.0 ± 0.1mg sample/cm2Dosage, test is spread evenly across in trial zone using latex finger cot.It is small to smear measurement 1 respectively
When, 2 hours, 4 hours, the moisture content of skin (measuring when verifying by this time) in tested region and blank control region was same
The test of volunteer is completed by the same survey crew.
The MMV value of each period is measured by the design decibel of experiment.Its moisture content calculation formula is as follows:
W%=(W1-W0)/W0 × 100%
W%: skin moisture content increases percentage；
W0: skin moisture content before product is used；
W1: skin moisture content after product is used；
3.5 test result
Measure the MMV value of each period respectively by the design of experiment.
4 skin moisture content incrementss of table
The result shows that: by 1.5 hours evaluate and test, prescription of the present invention can by skin moisture content improve 99.75%~
115.44%, relatively each control sample, the moisturizing effect of example sample is more significant (p < 0.05), compared with example sample 3, extract dosage
There are statistical difference (p < 0.05) with example sample 3 for moisturizing effect in comparable 3 controls (control sample 2~4).Wherein, real
Example sample 3 moisturizing effect also conspicuousness be better than other each example samples, there are statistical significance, p < 0.05 for the effect.As a result it says
Bright, the significant effect of composition provided by the present application is better than lacking constituent part or each group distribution ratio improperly sample.
The above is only the preferred embodiment of the present invention, it is noted that those skilled in the art are come
It says, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications also should be regarded as
Protection scope of the present invention.
Claims (10)
1. a kind of composition is grouped as by the group of following mass parts:
2. composition according to claim 1, which is characterized in that the mass parts of each component are as follows:
3. composition according to claim 1 or 2, which is characterized in that further include: glycerol, propylene glycol, butanediol, oligomerization
Sodium Hyaluronate, niacinamide, inositol and allantoin.
4. composition according to claim 3, which is characterized in that the mass parts of each component are as follows:
5. the described in any item compositions of Claims 1 to 4 inhibit skin oil and fat content, raising skin moisture content in preparation,
The application in cosmetics for inhibiting moisture of skin lost.
6. a kind of cosmetics, which is characterized in that including the described in any item compositions of Claims 1 to 4.
7. cosmetics according to claim 6, which is characterized in that wherein:
The mass fraction of composition of any of claims 1 or 2 is 0.19%~6.35%；
Or the mass fraction of composition described in claim 3 or 4 is 9.45%~15.76%.
8. cosmetics according to claim 6 or 7, which is characterized in that it is mildy wash, toner, lotion, essence, face
Film, face cream, shampoo or bath oil.
9. a kind of facial mask comprising mask matrix and facial mask liquid；
The group of the following mass fraction of facial mask liquid is grouped as:
10. the preparation method of facial mask liquid as claimed in claim 9 characterized by comprising
By water, glycerol, propylene glycol, butanediol, oligomerization Sodium Hyaluronate, niacinamide, inositol, allantoin, glycosylglycerol mixing,
75 DEG C~80 DEG C are heated to, 300r/min~400r/min stirs 30min；
It is cooled to 55 DEG C~60 DEG C, is added grape fruit extract, Flos Bombacis Malabarici extract and the ocean matt factor, 200r/min~
300r/min stirs 15min；
45 DEG C~50 DEG C are cooled to, glycylglycine and preservative is added, 200r/min~300r/min stirs 30min, is cooled to
Facial mask liquid is made in room temperature.
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| CN201811100563.2A CN109010246A (en) | 2018-09-20 | 2018-09-20 | A kind of cosmetics of composition and oil-control water weighing apparatus |
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| CN201811100563.2A CN109010246A (en) | 2018-09-20 | 2018-09-20 | A kind of cosmetics of composition and oil-control water weighing apparatus |
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Application publication date: 20181218 |