CN108815008A - A kind of composition and the careful cosmetics of oil-control - Google Patents

A kind of composition and the careful cosmetics of oil-control Download PDF

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Publication number
CN108815008A
CN108815008A CN201811100131.1A CN201811100131A CN108815008A CN 108815008 A CN108815008 A CN 108815008A CN 201811100131 A CN201811100131 A CN 201811100131A CN 108815008 A CN108815008 A CN 108815008A
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skin
composition
cosmetics
test
oil
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CN108815008B (en
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戴跃锋
康文术
何广文
颜少慰
汤芬
钱景茹
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Syoung Cosmetics Manufacturing Co Ltd
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HUNAN YUJIA COSMETICS MANUFACTURING Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/008Preparations for oily skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Botany (AREA)
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  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to the cosmetics that cosmetic technical field more particularly to a kind of composition and oil-control are careful.In composition provided by the invention, including:Grape fruit extract, the ocean matt factor and glycylglycine compounding, the composition of formation can have good control skin oil and fat content, improve skin moisture content, inhibit moisture of skin to scatter and disappear, the effect of careful pore.In composition, each component is indispensable, cooperates and generates the effect of synergy collaboration, and under suitable proportion, the effect of composition reaches best.

Description

A kind of composition and the careful cosmetics of oil-control
Technical field
The present invention relates to the cosmetics that cosmetic technical field more particularly to a kind of composition and oil-control are careful.
Background technique
Sebaceous glands is the holocrine gland being made of acinus and short conduit, and sebaceous gland duct is opened on hair follicle.In addition to hand Remaining area skin in have sebaceous glands, forehead, nose, the sebaceous glands in back portion are most, referred to as seborrhea position.Remaining Position is fewer, and the palm, toes and instep do not have sebaceous glands.Sebaceous glands is located between hair follicle and arrectores pilorum mostly, by one or several The acinus of a cryptomere and a common tubulature are constituted.Secretory portion is in vesica shape, is made of multilayer gland cell.Acinus periphery is tight The cell for pasting basement membrane is smaller, is in flat or cube, referred to as basal cell.Newborn gland cell is constantly mobile to center, and volume increases Add, intracytoplasmic small fat drips are more and more, and the cell at acinus center is bigger, and karyopyknosis, organelle disappear, and are full of in cytoplasm Fat drips.Last gland cell disintegrates and is discharged simultaneously with fat drips, as sebum.
The secretion of sebaceous glands is different due to the factors such as ethnic group, age, gender and weather.Secretion power is weak before 10 years old, 16~ Secretion in 35 years old is most vigorous, and the senescence phase weakens;Summer secretion is vigorous, and autumn and winter secretion is less;The food of greasy, the pungent stimulation of overfeeding And massage can also increase secretion.Smegma is vigorous, and it is coarse to can lead to skin greasing, pachylosis, pore, is easy to happen Acne and seborrhea.Sebaceous gland atrophy, sebum secreted is very few, can lead to dry skin, furfur, skin aging etc., so The secretion for controlling sebaceous glands is very crucial.
Sebum has many functions and effect for human body:It adjusts body temperature, the barrier function for maintaining skin, moisturizing and moistens Hair and skin produce skin and injure (UV) from latent lesion substance bring, and help transmits antioxidant, antibacterial agent, Anti-inflammatory agent and proinflammatory inflammation factor.The more and flourishing sebaceous glands of quantity and thick thick cuticula, so that male's skin is with respect to female Property want aging to obtain slowly, and elasticity it is good compared with women.But sebum excessive secretion can cause the skin problem of some worries:Have white The inflammation of interleukin 1L-8,1L-6 induction causes skin to thicken due to abnormal decortication and the hyperkeratinization of hair follicle;Excessive oil Rouge secretion leads to clogging of pores, acne easy to form, acne.To generate unsound influence to skin, cell and bacterium are connect Touching generates active chalcogen, brings oxidative pressure, and the enzyme for being responsible for removing oxidative pressure can't bear the heavy load, such as superoxide dismutase (SOD) With glutathione (GSH), relevant gene, such as glutamic acid are synthesized to it, the subunit of cysteine ligase synthesizes expression quantity Not enough, cellular damage is generated.
Therefore, sebum secretion amount is adjusted, skin moisture is replenished in time, skin water profit, careful hair follicle is kept to become cosmetics Research and development focus.
Summary of the invention
In view of this, the technical problem to be solved in the present invention is that provide a kind of composition and the careful cosmetics of oil-control, The composition can control skin oil and fat content, improve skin moisture content, inhibit moisture of skin lost and the careful hair follicle of energy.
Composition provided by the invention is grouped as by the group of following mass parts:
0.01 part~1 part of grape fruit extract;
0.05 part~1 part of the ocean matt factor;
0.01 part~0.5 part of glycylglycine.
In the embodiment of the present invention, the mass parts of each component are in composition:
1 part of grape fruit extract;
0.5 part of the ocean matt factor;
0.1 part of glycylglycine.
In the embodiment of the present invention, the mass parts of each component are in composition:
0.01 part of grape fruit extract;
0.05 part of the ocean matt factor;
0.01 part of glycylglycine.
In the embodiment of the present invention, the mass parts of each component are in composition:
1 part of grape fruit extract;
1 part of the ocean matt factor;
0.5 part of glycylglycine.
Grape fruit extract is extracted by the fruit of grape fruit (Citrus paradisi, also known as grapefruit) and is obtained, mainly Ingredient is aurantiamarin, has anti-oxidant, anti-inflammatory, antibacterial, absorbs ultraviolet light and anti-allergic effects
The ocean matt factor (matmarine) is to replace the born of the same parents that unicellular strain obtains from ocean vacation by biotechnology Outer polymer, can reduce MC5-R (with sebaceous differentiation in relation to) protein level;Reduce accumulation and the sebum of sebum lipid The maturation of gland cell;Inducing type I collagen synthesis reduces lipid peroxidation, reduces the expression of inflammation-related gene, increase with The expression of anti-oxidant related gene.
Glycylglycine (Glycylglycine also known as L-Glycylglycine), can make white Jie of keratinocyte caused by oleic acid The increase of plain 1L-1 α is inhibited, can intracellular ion caused by stabilizing unsaturated fatty acid it is unbalance, to make inflammatory Cell factor generation is inhibited, and can not only reduce the structure that pore expands outwardly, while can also improve the skin around pore State.
The present invention compounds grape fruit extract, the ocean matt factor and glycylglycine, and the composition of formation can have Good control skin oil and fat content improves skin moisture content, inhibits moisture of skin to scatter and disappear, the effect of careful pore.Combination In object, each component is indispensable, cooperates and generates the effect of synergy collaboration, and under suitable proportion, the effect of composition reaches To best.
In some embodiments, composition of the present invention further includes:Glycerol, propylene glycol, butanediol, oligomerization hyaluronic acid Sodium, niacinamide, inositol and allantoin.
Glycerol, propylene glycol, butanediol, oligomerization Sodium Hyaluronate, niacinamide, inositol and the further Assisted Combinatorial of allantoin Object plays effect, improves function of the composition in terms of moisturizing, moisturizing, oil-control, careful pore.
In these embodiments, in composition of the present invention, the mass parts of each component are:
In some specific embodiments, the mass parts of each component are in the composition:
In some specific embodiments, the mass parts of each component are in the composition:
In some specific embodiments, the mass parts of each component are in the composition:
Composition provided by the invention inhibits skin oil and fat content, raising skin moisture content in preparation, inhibits skin water Disperse the application lost, in the cosmetics of careful hair follicle.
Experiments verify that composition provided by the invention, to the facial area T fat content increase be suppressed to 272.73%~ 581.82%, have the function of preferably to control fat secretion.It is 1.56%~4.74% to the inhibiting rate that moisture of skin scatters and disappears, says Bright the composition has preferable reparation skin barrier ability.To the increasing action of skin moisture content up to 66.76%~ 81.58%, illustrate that the composition has the preferable ability for promoting skin moisture content.Composition of the present invention is preferably Man uses, so can be added into male cosmetic.
The present invention also provides a kind of cosmetics comprising composition of the present invention.
In cosmetics of the present invention:
The mass fraction of the composition is 0.07%~2.5%;Or the mass fraction of composition be 9.33%~ 11.76%.
The cosmetics are mildy wash, toner, lotion, essence, facial mask, face cream, shampoo or bath oil.The makeup Product are male cosmetic.
The present invention also provides a kind of facial masks comprising mask matrix and facial mask liquid;
The group of the following mass fraction of facial mask liquid is grouped as:
The preservative is PHL.
The preparation method of facial mask liquid of the present invention, including:
By water, glycerol, propylene glycol, butanediol, oligomerization Sodium Hyaluronate, niacinamide, inositol, allantoin mixing is heated to 75 DEG C~80 DEG C, 300r/min~400r/min stirs 30min;
55 DEG C~60 DEG C are cooled to, grape fruit extract is added and the ocean matt factor, 200r/min~300r/min are stirred Mix 15min;
45 DEG C~50 DEG C are cooled to, glycylglycine and preservative is added, 200r/min~300r/min stirs 30min, cold But room temperature is arrived, facial mask liquid is made.
In composition provided by the invention, including:Grape fruit extract, the ocean matt factor and glycylglycine compounding, shape At composition can have good control skin oil and fat content, improve skin moisture content, inhibit moisture of skin scatter and disappear, is thin Cause the effect of pore.In composition, each component is indispensable, cooperates and generates the effect of synergy collaboration, in suitable proportion Under, the effect of composition, reaches best.
Detailed description of the invention
Fig. 1 shows the face's area T fat content increment of each sample;
Fig. 2, which shows that the moisture of skin of each sample scatters and disappears, to be reduced;
Fig. 3 shows that the skin moisture content of each sample increases;
Fig. 4 shows the pore degree visibility sensory evaluation of each sample.
Specific embodiment
The present invention provides the cosmetics that a kind of composition and oil-control are careful, those skilled in the art can be used for reference in this paper Hold, is suitably modified realization of process parameters.In particular, it should be pointed out that all similar substitutions and modifications are to those skilled in the art For be it will be apparent that they are considered as being included in the present invention.Method and application of the invention, which has passed through, preferably to be implemented Example is described, related personnel obviously can not depart from the content of present invention, in spirit and scope to methods herein and application It is modified or appropriate changes and combinations, carrys out implementation and application the technology of the present invention.
The test material that the present invention uses is all common commercially available product, can all be bought in market.
Below with reference to embodiment, the present invention is further explained:
Embodiment
Each group of formula such as table 1:
1 each group of formula (wt%) of table
Deionized water, glycerol, propylene glycol, butanediol, oligomerization Sodium Hyaluronate, niacinamide, inositol, urine are weighed according to the proportion Bursin is heated to 75~80 DEG C, with 300r/min~400r/min, stirs 30min, dissolves to all substances transparent;
55~60 DEG C are cooled the temperature to, grape fruit extract, ocean matt factor component, with 200~300r/ are separately added into Min is stirred 15 minutes;
Temperature is reduced to 45~50 DEG C, glycylglycine and preservative PHL is added, 30min is stirred with 200-300r/min, It is cooled to room temperature and facial mask liquid is made.
Effect evaluation and test
1 oil-control efficacy assessments
1.1 test philosophy
This patent carries out the function of oil-Absorbing Sheets using effect using the skin oil and fat tester Sebumeter SM815 of Germany CK Effect evaluation.Oil content test is using universally acknowledged SEBUMETER method, it is based on photometer principle, and a kind of 0.1mm is thick After special delustring adhesive tape absorbs grease on human skin, a kind of translucent adhesive tape just will become, its light transmission capacity will be sent out The grease of changing, absorption is more, and light transmission capacity will be bigger, can thus measure the content of skin oil and fat.It is maximum excellent Point is that test probe size is small, easy to use, can test any position of skin.This is a kind of indirect survey of grease glandular secretion object As a result amount method can be used to distinguish different skin types, make accurately to understand the grease as caused by inside and outside reason Variation is possibly realized.
1.2 test method
This patent this time tests 21 test objects of selection, and 3 one group of people are divided into 7 groups, respectively forehead draw 3 having a size of The region 3cm × 3cm carries out the evaluation and test of skin oil and fat content for blank sample (not wipe samples), control sample and patent sample respectively, often A control sample takes the three related judges of value calculating fat content increment percentage progress for each person.
(1) the test object skin health selected, 18-30 years old age male, object is known after tested, is agreed to, tested right After face cleaning 15 minutes, its forehead fat content is measured as initial value.
(2) sample is not smeared in subject's forehead blank area, control sample area, patent sample area weigh 0.5ml Essence with 3cm After × 3cm non-woven membrane cloth infiltrates cover skin 20min, non-woven fabrics is removed, waits for quietly 10 minutes, is carried out respectively for three regions Fat content measurement, every 30min test is primary, persistently evaluates and tests 2h;
(3) environment is tested:T=25 DEG C of environment temperature of test, humidity H=50;
(4) testing time:Face cleaning is carried out before testing, is tested initial fat content within 15 minutes, is tested 30min respectively, 60min, 90min, 120min test grease content data;
(5) test position:Forehead marks blank, control sample, the test zone of patent sample.
1.3 effect evaluation results
2 fat content increment (%) of table
As shown in Table 2:It evaluated and tested by 3 hours, is increased using three of example sample 1~3 of the invention tested group greases Amount is 272.73%~581.82%, and relatively each control sample, the fat content using the subject of example sample is lower, illustrated example The suppression oil significant effect of sample 1~3 is better than each control sample (p<0.05), compared with example sample 3, extract dosage comparable 3 right According to the suppression oil effect in (control sample 2~4), there are statistical difference (p with example sample 3<0.05).Wherein, the suppression oil of example sample 3 Effect also conspicuousness be better than other each example samples, there are statistical significance, p for the effect<0.05.As a result illustrate, the application mentions It supplies
The significant effect of composition is better than lacking constituent part or each group distribution ratio improperly sample.
2 percutaneous moisture loss evaluations
2.1 test philosophy
The measuring principle of the test apparatus derives from FICK Fick's law of diffusion:Dm/dt=D.A.dp/dx.Pass through two groups Temperature-humidity sensor measures the water vapor pressure ladder that nearly epidermis (about in 1cm) is formed by cuticula moisture loss in different bright spots Degree, directly measures the amount of moisture percutaneously distributed.TEWL value is an important symbol of skin barrier quality, and the TEWL value of skin is got over It is low, illustrate that the barrier function of skin is better, on the contrary it is poorer.
(2) experimental condition and volunteer require
Test environment conditions:Testing environment temperature is 22 ± 1 DEG C, and humidity is 50 ± 5%, and carries out dynamic in real time and examine It surveys;
Volunteer requires:Effective volunteer at least 30 people, age male volunteers between 16-65 years old:Forearm test section Domain capacitance method moisture of skin measures the basic value of meaning between 15-100:Without serious systemic disease, no immune deficiency or itself Immunity disease person;No active anaphylactic disease person;Previously to skin-care cosmetics without severe allergy history person;In nearly one month not Once hormone medicine and immunosuppressor person are used:To participate in other clinical test persons;Use according to regulations test medicine and data It is complete;All volunteers should fill in informed consent form before testing;
(3) prepare before test
Any product (cosmetics or topical drug) cannot be used within 2-3 days before recipient site.Before experiment, subject needs same It is surveyed in meaning cleaning both hands forearm, with dry face tissue wiped clean.It is surveyed in subject's both hands forearm after cleaning and carries out measured zone Label.At least 30min that sits quietly in room should be being complied with standard before official testing, cannot drunk water, forearm exposure is put in test mode It sets, keeps loosening.
(4) testing procedure
3 × 3cm of label on the inside of left and right arm in experiment2Test area, same arm can mark multiple regions, interregional Every 1cm.Test product and blank control are randomly dispersed in left and right arm.Tested area is carried out using capacitance method skin analyzer The measurement in domain and control zone.Each region is according to parallel determination 15 times.The plain pape for first measuring each test zone, is then pressed 2.0 ± 0.1mg sample/cm2Dosage, test is spread evenly across in trial zone using latex finger cot.Smearing measures 1,2 respectively Hour, 4 hours, the moisture content of skin (being measured when verifying by this time) in tested region and blank control region, the same aspiration The test of person is completed by the same survey crew.
Measure the TEWL value of day part respectively by experimental design, the lost reduction calculation formula of moisture of skin is as follows:
T%=(T0-T1)/T0 × 100%
T%:Moisture of skin, which scatters and disappears, reduces percentage;
T0:Use moisture of skin windage before product;
T1:Use moisture of skin windage after product;
2.2 test result
Measure the TEWL value of day part respectively by experimental design.
3 moisture of skin of table scatters and disappears reduction amount
Note:Negative value is represented in table increases relative to T0 moisture of skin windage;
Positive value is represented to be reduced relative to T0 moisture of skin windage.
As the result is shown:Prescription of the present invention is evaluated and tested, tested group of moisture loss of example sample 1~3 by moisture of skin rate of scattering and disappearing Reduction amount is 1.56%~4.74%, the inhibitory effect of relatively each control sample, the better effect of each example sample, p<0.05, with reality Example sample 3 is compared, and there is also statistics with example sample 3 for the moistening effect in comparable 3 controls (control sample 2~4) of extract dosage Learn difference (p<0.05).Wherein, the moistening effect of example sample 3 also conspicuousness be better than other each example samples, the effect exist system Meter learns meaning, p<0.05.As a result illustrate, the moistening effect of composition provided by the present application be significantly better than lack constituent part or Each group distribution ratio improperly sample.
3 skin moisture content MMV test methods
3.1 test philosophy
For the method using the moisture content of capacitance method test human body keratoderma, its principle is based on water and other objects The difference in dielectric constant of matter is significant, and according to moisture content of skin difference, the capacitance for measuring skin is different, and observed parameter can represent Skin moisture value.
Test equipment:
German CK company Multi-functional skin tester, model C UTOMETER DUAL MPA580, this patent select skin water Content measuring probe and the lost TEWL test of moisture of skin is divided to pop one's head in.
3.2 experimental conditions and volunteer require
Test environment conditions:Testing environment temperature is 22 ± 1 DEG C, and humidity is 50 ± 5%, and carries out dynamic in real time and examine It surveys;
Volunteer requires:Effective volunteer at least 30 people, age male between 16-65 years old:Forearm test zone capacitor Method moisture of skin measures the basic value of meaning between 15-100:Without serious systemic disease, no immune deficiency or autoimmune Disease patient;No active anaphylactic disease person;Previously to skin-care cosmetics without severe allergy history person;It was not used in nearly one month Hormone medicine and immunosuppressor person:To participate in other clinical test persons;Use according to regulations test medicine and all information;It surveys All volunteers should fill in informed consent form before trying;
Prepare before 3.3 tests
Any product (cosmetics or topical drug) cannot be used within 2-3 days before recipient site.Before experiment, subject needs same It is surveyed in meaning cleaning both hands forearm, with dry face tissue wiped clean.It is surveyed in subject's both hands forearm after cleaning and carries out measured zone Label.At least 30min that sits quietly in room should be being complied with standard before official testing, cannot drunk water, forearm exposure is put in test mode It sets, keeps loosening.
3.4 testing procedure
3 × 3cm of label on the inside of left and right arm in experiment2Test area, same arm can mark multiple regions, interregional Every 1cm.Test product and blank control are randomly dispersed in left and right arm.Tested area is carried out using capacitance method skin analyzer The measurement in domain and control zone.Each region is according to parallel determination 15 times.The plain pape for first measuring each test zone, is then pressed 2.0 ± 0.1mg sample/cm2Dosage, test is spread evenly across in trial zone using latex finger cot.It is small to smear measurement 1 respectively When, 2 hours, 4 hours, the moisture content of skin (measuring when verifying by this time) in tested region and blank control region was same The test of volunteer is completed by the same survey crew.
The MMV value of each period is measured by the design decibel of experiment.Its moisture content calculation formula is as follows:
W%=(W1-W0)/W0 × 100%
W%:Skin moisture content increases percentage;
W0:Use skin moisture content before product;
W1:Use skin moisture content after product;
3.5 test result
Measure the MMV value of each period respectively by the design of experiment.
4 skin moisture content incrementss of table
The result shows that:By 1.5 hours evaluate and test, prescription of the present invention can by skin moisture content improve 66.76%~ 81.58%, relatively each control sample, the more significant (p of the moisturizing effect of example sample<0.05), compared with example sample 3, extract dosage There are statistical difference (p with example sample 3 for moisturizing effect in comparable 3 controls (control sample 2~4)<0.05).Wherein, real Example sample 3 moisturizing effect also conspicuousness be better than other each example samples, there are statistical significance, p for the effect<0.05.As a result it says Bright, the significant effect of composition provided by the present application is better than lacking constituent part or each group distribution ratio improperly sample.
4, pore visibility evaluation
4.1 assessment models
For the coarse skin of hypersteatosis and pore, sense organ evaluation and test is carried out using clinical score mode.
4.2 volunteers selection
28 healthy male volunteers are selected, the age is -45 years old 18 years old, with one group of 4 people, is divided into 7 groups, uses for sample Cross-reference scoring, sample four are scored at clinical score with it for each person.
Volunteer's sebum levels are greater than or equal to 190 μ g/cm2
4.3 operational version
Volunteer is respectively using evaluation and test sample, and half of face uses sooner or later daily, is used continuously 14 days.
4.4 clinical score tables are as follows
By 6 grades of classified estimations of the coarse degree of facial pores point:
5 standards of grading of table
Pore classification Evaluation description Scoring Remarks
1 grade Few visible pore 10
2 grades Slight visible pore 8
3 grades High-visible pore 6
4 grades Clearly visible pore includes the keratotic plug less than pore size 4
5 grades Clearly visible pore or include and pore keratotic plug of the same size 2
6 grades The obvious keratotic plug for expanding pore or the prominent pore of intension, is presented strawberry sample 0
4.5 evaluation result
6 appraisal result of table
Project Control sample 1 Control sample 2 Control sample 3 Control sample 4 Example sample 1 Example sample 2 Example sample 3
Scoring 4.7 5.8 6.9 4.5 7.2 8.6 9.1
The result shows that:By evaluation and test in 14 days, prescription of the present invention can be improved the scoring of facial pores, relative comparison sample 1 ~2,4, the more significant (p of the effect of the compact pore of each example sample<0.05), compared with example sample 3, extract dosage comparable 3 There are statistical difference (p with example sample 3 for the effect of compact pore in a control (control sample 2~4)<0.05).Wherein, example The effect of the compact pore of sample 3 also conspicuousness be better than other each example samples, there are statistical significance, p for the effect<0.05.Knot Fruit explanation, the significant effect of composition provided by the present application are better than lacking constituent part or each group distribution ratio improperly sample.
The above is only the preferred embodiment of the present invention, it is noted that those skilled in the art are come It says, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications also should be regarded as Protection scope of the present invention.

Claims (10)

1. a kind of composition is grouped as by the group of following mass parts:
0.01 part~1 part of grape fruit extract;
0.05 part~1 part of the ocean matt factor;
0.01 part~0.5 part of glycylglycine.
2. composition according to claim 1, which is characterized in that the mass parts of each component are:
1 part of grape fruit extract;
0.5 part of the ocean matt factor;
0.1 part of glycylglycine.
3. composition according to claim 1 or 2, which is characterized in that further include:Glycerol, propylene glycol, butanediol, oligomerization Sodium Hyaluronate, niacinamide, inositol and allantoin.
4. composition according to claim 3, which is characterized in that the mass parts of each component are:
5. the described in any item compositions of Claims 1 to 4 inhibit skin oil and fat content, raising skin moisture content in preparation, Moisture of skin is inhibited to scatter and disappear, the application in the cosmetics of careful hair follicle.
6. a kind of cosmetics, which is characterized in that including the described in any item compositions of Claims 1 to 4.
7. cosmetics according to claim 6, which is characterized in that wherein:
The mass fraction of composition of any of claims 1 or 2 is 0.07%~2.5%;
Or the mass fraction of composition described in claim 3 or 4 is 9.33%~11.76%.
8. cosmetics according to claim 6 or 7, which is characterized in that it is mildy wash, toner, lotion, essence, face Film, face cream, shampoo or bath oil.
9. a kind of facial mask comprising mask matrix and facial mask liquid;
The group of the following mass fraction of facial mask liquid is grouped as:
10. the preparation method of facial mask liquid as claimed in claim 9, which is characterized in that including:
By water, glycerol, propylene glycol, butanediol, oligomerization Sodium Hyaluronate, niacinamide, inositol, allantoin mixing is heated to 75 DEG C ~80 DEG C, 300r/min~400r/min stirs 30min;
55 DEG C~60 DEG C are cooled to, grape fruit extract and the ocean matt factor, 200r/min~300r/min stirring is added 15min;
45 DEG C~50 DEG C are cooled to, glycylglycine and preservative is added, 200r/min~300r/min stirs 30min, is cooled to Facial mask liquid is made in room temperature.
CN201811100131.1A 2018-09-20 2018-09-20 Composition and oil-controlling delicate cosmetic Active CN108815008B (en)

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CN112826772A (en) * 2021-02-01 2021-05-25 广州市美意化妆品有限公司 Pore-shrinking essence and preparation method thereof

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