CN108992497A - A kind of disinfectant liquid for skin and preparation method thereof - Google Patents
A kind of disinfectant liquid for skin and preparation method thereof Download PDFInfo
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- CN108992497A CN108992497A CN201811099129.7A CN201811099129A CN108992497A CN 108992497 A CN108992497 A CN 108992497A CN 201811099129 A CN201811099129 A CN 201811099129A CN 108992497 A CN108992497 A CN 108992497A
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- 239000007788 liquid Substances 0.000 title claims abstract description 35
- 239000000645 desinfectant Substances 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 27
- 235000019441 ethanol Nutrition 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 18
- 239000012530 fluid Substances 0.000 claims description 16
- 239000008213 purified water Substances 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000003814 drug Substances 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 6
- 239000004615 ingredient Substances 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 3
- 238000004821 distillation Methods 0.000 claims description 3
- 229940079593 drug Drugs 0.000 claims description 3
- 235000008216 herbs Nutrition 0.000 claims description 3
- 238000007689 inspection Methods 0.000 claims description 3
- 238000004806 packaging method and process Methods 0.000 claims description 3
- 238000001556 precipitation Methods 0.000 claims description 3
- 238000012545 processing Methods 0.000 claims description 3
- 238000002791 soaking Methods 0.000 claims description 3
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 2
- 241000736199 Paeonia Species 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 15
- 230000000694 effects Effects 0.000 abstract description 9
- 230000035876 healing Effects 0.000 abstract description 4
- 230000001954 sterilising effect Effects 0.000 abstract description 4
- 239000002994 raw material Substances 0.000 abstract description 3
- 241000411851 herbal medicine Species 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 description 4
- 206010052428 Wound Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 4
- 229940033663 thimerosal Drugs 0.000 description 4
- 230000006378 damage Effects 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 244000170916 Paeonia officinalis Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
A kind of disinfectant liquid for skin, the component including following parts by weight: 20 ~ 30 parts of cortex moutan, 20 ~ 30 parts of radix scutellariae, 15 ~ 20 parts of Radix Paeoniae Alba, 15 ~ 20 parts of Fructus Forsythiae, the invention also discloses a kind of preparation methods of disinfectant liquid for skin.Raw material in the present invention are Chinese herbal medicine, non-toxic to humans, the effect for the sterilization that can carry out disinfection to wound, the healing that can promote wound simultaneously, carries out disinfection to skin, and the technical solution raw material sources in the present invention are wide, preparation method is simple, and range applicatory is wide.
Description
Technical field
The present invention relates to sterile products technical fields, and in particular to a kind of disinfectant liquid for skin and preparation method thereof.
Background technique
With the development and progress of economic society, the raising of people's quality of life, disinfection and sterilization and environmentally protective consciousness
Also increase suddenly.Thimerosal traditional at present is all chemicals, although effect meditation, Disinfection Effect is good, chemical disinfection
Ingredient in liquid is more toxic, and after spraying in air, digestive system and respiratory system to people all cause certain damage, bright
It is aobvious to violate people's pursuit environmentally protective to health.
Modern will contact articles for washing daily, and the consumption used is big, but the harm being subject to while disinfection and sterilization
And it is immeasurable, natural medicinal plant has had become international trend, and disinfectant is each public place hospital, guest
Shop, family, catering trade necessary consumer goods, existing disinfectant mainly has chlorine product, Iodophor, glutaraldehyde etc., chlorine product and iodine
The poor stability of volt is its maximum disadvantage；The bactericidal effect of glutaraldehyde is strong, but side effect is big, and corrosivity is strong, the change used
It learns when disinfection medical fluid reaches a certain concentration and is more toxic, will cause the medicine source hurt of mucous membrane tissue.
Disinfectant liquid for skin in the prior art contains chemical component more, cannot play the role of benign, length to the healing of wound
Phase using that can generate certain toxicity and corrosivity injured cutaneous tissue, therefore, develops the benign good plant type of a kind of pair of skin
The emphasis of thimerosal current research.
Summary of the invention
The main object of the present invention is to provide a kind of disinfectant liquid for skin and preparation method thereof, mainly with cortex moutan, radix scutellariae,
Radix Paeoniae Alba and Fructus Forsythiae are raw material, can carry out disinfection to skin, not damage to skin, and Disinfection Effect is good, there is preferable promotion wound
The effect of healing, can't generate stimulation and toxicity, suitable and skin contact to skin.
To achieve the above object, the technical solution adopted by the present invention are as follows: a kind of disinfectant liquid for skin, including following parts by weight
Component: 20 ~ 30 parts of cortex moutan, 20 ~ 30 parts of radix scutellariae, 15 ~ 20 parts of Radix Paeoniae Alba, 15 ~ 20 parts of Fructus Forsythiae.
Preferably, a kind of disinfectant liquid for skin, the component including following parts by weight: 23 parts of cortex moutan, 23 parts of radix scutellariae,
16 parts of Radix Paeoniae Alba, 16 parts of Fructus Forsythiae.
Preferably, a kind of disinfectant liquid for skin, the component including following parts by weight: 25 parts of cortex moutan, 25 parts of radix scutellariae,
18 parts of Radix Paeoniae Alba, 18 parts of Fructus Forsythiae.
Preferably, a kind of disinfectant liquid for skin, the component including following parts by weight: 27 parts of cortex moutan, 27 parts of radix scutellariae,
20 parts of Radix Paeoniae Alba, 20 parts of Fructus Forsythiae.
A kind of preparation method of above-mentioned disinfectant liquid for skin, comprising the following steps:
(1) prepare medicinal material and cleaned and impregnated: is 20 ~ 30 parts of radix scutellariae, white by 20 ~ 30 parts of cortex moutan of following parts by weight
15 ~ 20 parts of Chinese herbaceous peony, the medicinal material that 15 ~ 20 parts of Fructus Forsythiae carries out ingredient and medicinal material is carried out coarse crushing, impregnates after medicinal material is cleaned, if
Determining soaking time is 1h；
(2) decoct: by after above-mentioned mixed processing medicinal material and purified water weight fraction ratio be 1:7 or 1:5 ratio progress first
Medicinal material after first time decocts is added purified water to carry out second and decocted by secondary decoction, decocting time 2h after filtering, and second
The adding proportion of secondary decocting herbs and purified water is 1:5 or 1:3, decocting time 1.5h, is mixed after decocting twice after filtering
Decoction liquor；
(3) it is concentrated: above-mentioned decoction liquor being extracted into progress low temperature in concentration tank and vacuumizes concentration, is concentrated into medical fluid and crude drug weight
Until portion rate is 1:1；
(4) alcohol precipitation: the 3:1 of the additional proportion of 95% medicinal alcohol of addition, 3 ~ 5min of stirring, the medicinal alcohol and medical fluid, stirring
5~10min；
(5) it stands: standing 24 ~ 48h at 15 ~ 20 DEG C；
(6) it filters: vacuumizing filtration will be carried out in the sieve of 200 mesh by step 5 treated medical fluid；
(7) it recycles ethyl alcohol: extracting the ethyl alcohol in the DeviceMode progress released liquor vacuumized using distillation, make ethyl alcohol in medical fluid
Content control until 5 ~ 10%；
(8) it compounds: step 7 treated medical fluid is added to the purified water dilute liquid medicine of original liquid 20 ~ 30%；
(9) quality inspection packaging is stood.
Compared with prior art, beneficial effect of the invention is plant type Traditional Chinese medicine disinfectant in the disinfectant liquid for skin, is sterilized
Rate is strong, and human body is not stimulated and injured, and the function and effect antivirus time is long, there is antipruritic, disinfection and the effect for promoting wound healing,
The problems such as tinea pedis can be treated, carry out disinfection to wound and can be used as gynaecology's personal nursing liquid.
Specific embodiment
Below in conjunction with structural schematic diagram of the invention, the technical solution in specific embodiments of the present invention is carried out clear
Chu is fully described by.Obviously, described embodiment is only a part of the embodiments of the present invention, instead of all the embodiments.
Based on the embodiments of the present invention, those skilled in the art are obtained under the premise of not making the creative labor
Every other embodiment, belongs to protection scope of the present invention.
The technical solution adopted by the present invention are as follows: a kind of disinfectant liquid for skin, the component including following parts by weight: cortex moutan 20
~ 30 parts, 20 ~ 30 parts of radix scutellariae, 15 ~ 20 parts of Radix Paeoniae Alba, 15 ~ 20 parts of Fructus Forsythiae.
Embodiment 1
A kind of preparation method of disinfectant liquid for skin includes:
(1) prepare medicinal material and cleaned and impregnated: by 23 parts of cortex moutan of following parts by weight, 23 parts of radix scutellariae, 16 parts of Radix Paeoniae Alba,
The medicinal material that 16 parts of Fructus Forsythiae carries out ingredient and crushes medicinal material, impregnates after medicinal material is cleaned, sets soaking time as 1h；
(2) decoct: by after above-mentioned mixed processing medicinal material and purified water weight fraction ratio be 1:7 or 1:5 ratio progress first
Medicinal material after first time decocts is added purified water to carry out second and decocted by secondary decoction, decocting time 2h after filtering, and second
The adding proportion of secondary decocting herbs and purified water is 1:5 or 1:3, decocting time 1.5h, is mixed after decocting twice after filtering
Decoction liquor；
(3) it is concentrated: above-mentioned decoction liquor being extracted into progress low temperature in concentration tank and vacuumizes concentration, is concentrated into medical fluid and crude drug weight
Until portion rate is 1:1；
(4) alcohol precipitation: the 3:1 of the additional proportion of 95% medicinal alcohol of addition, 3 ~ 5min of stirring, the medicinal alcohol and medical fluid, stirring
5~10min；
(5) it stands: standing 24 ~ 48h at 15 ~ 20 DEG C；
(6) it filters: vacuumizing filtration will be carried out in the sieve of 200 mesh by step 5 treated medical fluid；
(7) it recycles ethyl alcohol: the equipment that vacuumizes being extracted using distillation and carries out ethyl alcohol in released liquor, make containing for ethyl alcohol in medical fluid
Amount control is 5 ~ 10%；
(8) it compounds: step 7 treated medical fluid is added to the purified water dilute liquid medicine of original liquid 20 ~ 30%；
(9) quality inspection packaging is stood.
Embodiment 2
A kind of preparation method of disinfectant liquid for skin is step same as Example 1, wherein a kind of disinfectant liquid for skin, including with
The component of lower parts by weight: 25 parts of cortex moutan, 25 parts of radix scutellariae, 18 parts of Radix Paeoniae Alba, 18 parts of Fructus Forsythiae.
Embodiment 3
A kind of preparation method of disinfectant liquid for skin is step same as Example 1, wherein a kind of disinfectant liquid for skin, including with
The component of lower parts by weight: 27 parts of cortex moutan, 27 parts of radix scutellariae, 20 parts of Radix Paeoniae Alba, 20 parts of Fructus Forsythiae.
Object table thimerosal is plant type thimerosal in technical solution of the present invention, and no chemical component will not be to human body and ring
Border carries out generation stimulation, and without toxicity, a small amount of entrance can't cause the medicine source hurt to mucous membrane tissue, with sterilizing
Effect, and can have the effect of certain promotion healing to disinfection wound, preparation method of the invention is simple, and manufacturing cost is low,
Suitable for being used in marketing.
Finally, it should be noted that being not intended to restrict the invention the above are the preferred embodiment of the present invention, although ginseng
According to previous embodiment, the present invention will be described in detail, still can be right for others skilled in the art
It modifies according to technical solution documented by various embodiments before, or part of technical characteristic is equally replaced
It changes.All within the spirits and principles of the present invention, any modification, equivalent substitution, improvement and etc. done should be included in the present invention
Protection scope within.
Claims (5)
1. a kind of disinfectant liquid for skin, it is characterised in that: the component including following parts by weight: 20 ~ 30 parts of cortex moutan, radix scutellariae 20 ~
30 parts, 15 ~ 20 parts of Radix Paeoniae Alba, 15 ~ 20 parts of Fructus Forsythiae.
2. a kind of disinfectant liquid for skin according to claim 1, it is characterised in that: a kind of disinfectant liquid for skin, including with
The component of lower parts by weight: 23 parts of cortex moutan, 23 parts of radix scutellariae, 16 parts of Radix Paeoniae Alba, 16 parts of Fructus Forsythiae.
3. a kind of disinfectant liquid for skin according to claim 1, it is characterised in that: a kind of disinfectant liquid for skin, including with
The component of lower parts by weight: 25 parts of cortex moutan, 25 parts of radix scutellariae, 18 parts of Radix Paeoniae Alba, 18 parts of Fructus Forsythiae.
4. a kind of disinfectant liquid for skin according to claim 1, it is characterised in that: a kind of disinfectant liquid for skin, including with
The component of lower parts by weight: 27 parts of cortex moutan, 27 parts of radix scutellariae, 20 parts of Radix Paeoniae Alba, 20 parts of Fructus Forsythiae.
5. the preparation method of any disinfectant liquid for skin described according to claim 1 ~ 4, it is characterised in that: including following step
It is rapid:
(1) prepare medicinal material and cleaned and impregnated: is 20 ~ 30 parts of radix scutellariae, white by 20 ~ 30 parts of cortex moutan of following parts by weight
15 ~ 20 parts of Chinese herbaceous peony, the medicinal material that 15 ~ 20 parts of Fructus Forsythiae carries out ingredient and medicinal material is carried out coarse crushing, impregnates after medicinal material is cleaned, if
Determining soaking time is 1h；
(2) decoct: by after above-mentioned mixed processing medicinal material and purified water weight fraction ratio be 1:7 or 1:5 ratio progress first
Medicinal material after first time decocts is added purified water to carry out second and decocted by secondary decoction, decocting time 2h after filtering, and second
The adding proportion of secondary decocting herbs and purified water is 1:5 or 1:3, decocting time 1.5h, is mixed after decocting twice after filtering
Decoction liquor；
(3) it is concentrated: above-mentioned decoction liquor being extracted into progress low temperature in concentration tank and vacuumizes concentration, is concentrated into medical fluid and crude drug weight
Until portion rate is 1:1；
(4) alcohol precipitation: the 3:1 of the additional proportion of 95% medicinal alcohol of addition, 3 ~ 5min of stirring, the medicinal alcohol and medical fluid, stirring
5~10min；
(5) it stands: standing 24 ~ 48h at 15 ~ 20 DEG C；
(6) it filters: vacuumizing filtration will be carried out in the sieve of 200 mesh by step 5 treated medical fluid；
(7) it recycles ethyl alcohol: the ethyl alcohol in the equipment released liquor vacuumized being extracted using distillation, makes the content control of ethyl alcohol in medical fluid
System is until 5 ~ 10%；
(8) it compounds: step 7 treated medical fluid is added to the purified water dilute liquid medicine of original liquid 20 ~ 30%；
Stand quality inspection packaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811099129.7A CN108992497A (en) | 2018-09-20 | 2018-09-20 | A kind of disinfectant liquid for skin and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811099129.7A CN108992497A (en) | 2018-09-20 | 2018-09-20 | A kind of disinfectant liquid for skin and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108992497A true CN108992497A (en) | 2018-12-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811099129.7A Pending CN108992497A (en) | 2018-09-20 | 2018-09-20 | A kind of disinfectant liquid for skin and preparation method thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN108992497A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101077362A (en) * | 2006-05-25 | 2007-11-28 | 西安格润森生物制药股份有限公司 | Plant-type skin mucosa disinfecting agent |
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2018
- 2018-09-20 CN CN201811099129.7A patent/CN108992497A/en active Pending
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|---|---|---|---|---|
| CN101077362A (en) * | 2006-05-25 | 2007-11-28 | 西安格润森生物制药股份有限公司 | Plant-type skin mucosa disinfecting agent |
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| 余惠平等，: "仙芍丹归草汤治疗小儿过敏性紫癜临床研究", 《中国中医药信息杂志》 * |
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Application publication date: 20181214 |
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