CN104189414A - External liquid medicine for skin diseases and preparation technology thereof - Google Patents
External liquid medicine for skin diseases and preparation technology thereof Download PDFInfo
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- CN104189414A CN104189414A CN201410476990.6A CN201410476990A CN104189414A CN 104189414 A CN104189414 A CN 104189414A CN 201410476990 A CN201410476990 A CN 201410476990A CN 104189414 A CN104189414 A CN 104189414A
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Abstract
The invention discloses an external liquid medicine for skin diseases and a preparation technology thereof. The producing raw materials of the liquid medicine comprise tomato juice, bioactive active enzymes, preservatives and traditional Chinese medicine materials. The preparation method comprises the following steps: preparing mother liquid with the raw materials of the tomato juice, the bioactive mildew and the preservatives, wherein the weight proportion of the raw materials of the tomato juice to the raw materials of the bioactive mildew and the raw materials of the preservatives is 100:4:1, adding 0.8 kg of traditional Chinese medicine materials to every 4 liters of mother liquid which is made of the tomato juice, the bioactive active enzymes and the preservatives, soaking the traditional Chinese medicine material in the mother liquid to prepare the liquid medicine, and filtering the traditional Chinese medicine materials after the traditional Chinese medicine materials are soaked for 7-10 days. The bioactive active enzymes are bean curds which are fermented. The preservatives are sodium benzoate. A part of the medicine materials is prepared from 5 g of rhizoma anemarrhenae, 5 g of phellodendron, 4 g of tree peony bark, 4 g of poria cocos, 4 g of rhizoma alismatis, 3 g of Chinese yam, 3 g of cornel and 4 g of digitalis. The external liquid medicine for the skin diseases has the curative effects of clearing heat, removing toxicity and resisting allergy. The external liquid medicine is mainly used for treating the skin diseases, such as whelk, pollinosis, solar dermatitis, neurodermitis, beriberi, ringworm, empyrosis and infrared injury, and is used for expelling mosquitoes, relieving itching and the like.
Description
Technical field
The present invention relates to external application Chinese medicine technical field, be specifically related to a kind of dermatosis external medicinal liquid and preparation technology thereof.
Background technology
Modern medicine study proves, dermatosis is mostly local patholoic change, generally has due to fungal infection.Different according to the position of dermatosis, can be divided into superfical mycoses and deep mycosis, superfical mycoses Yi Ban You Ringworm bacterium causes, is mainly the horny layer of invading epidermis, the internal organs such as skin deep part tissue and the heart, lung, digestive tract are involved in deep mycosis change.Candida albicans is deep mycete, easily causes shallow epidermis skin and mucosal infections.Although the treatment of selling on the market is at present better by the microbial deep of Ringworm mycete medicine for external use curative effect, all easily produces Resistant strain, low to the suppression ratio of pathogenic bacteria, and washing liquid, the type that squeezes used inconvenience, most of by Acidity of Aikalinity, and skin is had to stimulation.Have again, the medicine that is used for the treatment of dermatosis of selling in the market, its curative effect all has unicity, and every kind of medicine can only have certain curative effect for a kind of dermatosis, or only a certain class crowd is had to certain curative effect.
Summary of the invention
The object of the invention is, overcomes defect of the prior art, and a kind of dermatosis external medicinal liquid and preparation technology thereof various skin disease all to therapeutic effect is provided.
For achieving the above object, technical scheme of the present invention is: a kind of dermatosis external medicinal liquid is provided, the raw materials for production of described medicinal liquid comprise Fructus Lycopersici esculenti juice, biological activity is mould, antiseptic and Chinese crude drug, Fructus Lycopersici esculenti juice, biological activity is mould, the raw material of antiseptic is 100:4:1 by weight ratio, by every 4 liters by Fructus Lycopersici esculenti juice, in the mother solution that biological activity is mould and antiseptic is mixed with, add 0.8 kilogram of Chinese crude drug proportioning preparating liquid, described biological activity is mould is the bean corruption after fermentation, described antiseptic is sodium benzoate, in described medical material, press every 5 grams of Rhizoma Anemarrhenaes, 5 grams of Cortex Phellodendris, 4 grams of Cortex Moutans, 4 grams of Poria, 4 grams of Rhizoma Alismatis, 3 Keshan medicines, 3 grams of Fructus Evodiaes and 4 grams of Radix Rehmanniae are 1 part and are configured.
Another technical scheme of the present invention is: a kind of preparation technology of above-mentioned dermatosis external medicinal liquid is provided, and described preparation technology comprises the steps:
Step 1, cleans Fructus Lycopersici esculenti to dry fragmentation;
Step 2 adds biological activity mould in Fructus Lycopersici esculenti, stirs, and makes fermentation Fructus Lycopersici esculenti;
Step 3, carries out slag, juice separation by the Fructus Lycopersici esculenti fermenting;
Step 4, is heated to boiling by isolated juice, again filters after cooling, and the juice after filtering is put into the container with seal cover, then to add antiseptic in container and stir after make mother solution;
Step 5, then Chinese crude drug is immersed in mother solution, then cover seal cover and seal up for safekeeping 7 to 10 days;
Step 6, deposits after 7 to 10 days the medicinal liquid of making after herbal medicine immersion is heated again, then filtering medicinal residues;
Step 7, by medicinal liquid bottling and encapsulation after filtering medicinal residues.
Preferred technical scheme is that in described step 3, the mould making step of biological activity comprises:
Step 1, is cut into 3 * 3 * 3 squares by bean curd;
Step 2, by the bean curd fermentation cutting 7 to 10 days;
Step 3, adds the Sal pressed compact that is no more than by weight percentage 5% in the bean curd after fermentation;
Step 4, adds 5% Alumen by weight percentage again by the good bean curd of pressed compact, then seals up for safekeeping 180 days～200 days.
Preferred technical scheme also has, and the ebuillition of heated temperature in described step 3 is 100 ℃, and described being cooled to is cooled to room temperature.
Preferred technical scheme also has, and the operation of squeezing the juice in described step 3 is to adopt pressure filter to carry out slag, juice separation.
Preferred technical scheme also has, and the Chinese crude drug in described step 5 soaks in mother solution at normal temperatures.
Preferred technical scheme also has, and in described step 6, the temperature of heating is 100 ℃ again, and the time of heating is 5～10 minutes.
Preferred technical scheme also has, and the Chinese crude drug in described step 5 was graininess by its pulverizing before soaking.
Further preferably technical scheme is, in described step 2, the ambient temperature of bean curd fermentation is 20 ℃～30 ℃, and ambient humidity is 70%～80%, and fermentation process is natural fermentation.
Further preferred technical scheme also has, and the ambient temperature that described step 3 is sealed up for safekeeping is 20 ℃～30 ℃, and is sealed up for safekeeping in the container of sealing lucifuge.
Advantage of the present invention and beneficial effect are, main component bean curd wide material sources during main component Fructus Lycopersici esculenti in this dermatosis external medicinal liquid and biological activity are mould, cheap, the addition of antiseptic is few, and selected middle medicinal herbs are conventional Chinese crude drug at a low price.The preparation technology of this dermatosis external medicinal liquid is simple, and production equipment used also seldom.This dermatosis external medicinal liquid has heat-clearing and toxic substances removing, antianaphylactic curative effect.Be mainly used in treating comedo, pollinosis, solar dermatitis, neurodermatitis,, beriberi, tinea, scald, red trauma.Repelling mosquito, the dermatosis such as antipruritic.
The specific embodiment
The present invention is a kind of dermatosis external medicinal liquid, the raw materials for production of described medicinal liquid comprise Fructus Lycopersici esculenti juice, biological activity is mould, antiseptic and Chinese crude drug, Fructus Lycopersici esculenti juice and biological activity are mould, the raw material of antiseptic is 100:4:1 by weight ratio, by every 4 liters by Fructus Lycopersici esculenti juice, in the mother solution that biological activity is mould and antiseptic is mixed with, add 0.8 kilogram of Chinese crude drug proportioning preparating liquid, described biological activity is mould is the bean corruption after fermentation, described antiseptic is sodium benzoate, in described medical material, press every 5 grams of Rhizoma Anemarrhenaes, 5 grams of Cortex Phellodendris, 4 grams of Cortex Moutans, 4 grams of Poria, 4 grams of Rhizoma Alismatis, 3 Keshan medicines, 3 grams of Fructus Evodiaes and 4 grams of Radix Rehmanniae are 1 part and are configured.
For example with Fructus Lycopersici esculenti juice, biological activity is mould with antiseptic is that preparation of raw material becomes the mother solution of 4000 milliliters, then at the Chinese crude drug that adds 800 grams, 800 grams of Chinese crude drugs that are equivalent to 25 parts.
Another technical scheme of the present invention is: a kind of preparation technology of above-mentioned dermatosis external medicinal liquid is provided, and described preparation technology comprises the steps:
Step 1, is broken into fritter by clean the drying of fresh Fructus Lycopersici esculenti;
Step 2 adds biological activity mould in Fructus Lycopersici esculenti, in 100 jin of Fructus Lycopersici esculenties, adds 4 jin of mould ratio preparations of biological activity, then stirs, and makes fermentation Fructus Lycopersici esculenti;
Step 3, carries out slag, juice separation by the Fructus Lycopersici esculenti fermenting;
Step 4, is heated to boiling by isolated juice, again filters after cooling, and the juice after filtering is put into the container with seal cover, then to add antiseptic in container and stir after make mother solution;
Step 5, then Chinese crude drug is immersed in mother solution, then cover seal cover and seal up for safekeeping 7 to 10 days;
Step 6, deposits after 7 to 10 days the medicinal liquid of making after herbal medicine immersion is heated again, then filtering medicinal residues;
Step 7, by medicinal liquid bottling and encapsulation after filtering medicinal residues.
The preferred embodiment of the invention is that in described step 3, the mould making step of biological activity comprises:
Step 1, is cut into 3 * 3 * 3 squares by bean curd;
Step 2, by the bean curd fermentation cutting 7 to 10 days;
Step 3, adds the Sal pressed compact that is no more than by weight percentage 5% in the bean curd after fermentation,
Step 4, adds 5% Alumen by weight percentage again by the good bean curd of pressed compact, then seals up for safekeeping 180 days～200 days.
The preferred embodiment of the invention also has, and the ebuillition of heated temperature in the preparation technology's of external medicinal liquid described step 3 is 100 ℃, and described being cooled to is cooled to room temperature.
The preferred embodiment of the invention also has, the preparation technology of external medicinal liquid described in the operation of squeezing the juice in step 3 be adopt pressure filter to carry out slag, juice is separated.
The preferred embodiment of the invention also has, and the Chinese crude drug in the preparation technology's of external medicinal liquid described step 5 soaks in mother solution at normal temperatures.
The preferred technical scheme of the present invention also has, and in the preparation technology's of external medicinal liquid described step 6, the temperature of heating is 100 ℃ again, and the time of heating is 5～10 minutes.
The preferred embodiment of the invention also has, and before the Chinese crude drug in the preparation technology's of external medicinal liquid described step 5 is soaking, its pulverizing is to graininess.
Further preferred embodiment of the present invention is, in the described step 2 of the mould processing technology of biological activity, the ambient temperature of bean curd fermentation is 20 ℃～30 ℃, and ambient humidity is 70%～80%, and fermentation process is natural fermentation.
Further preferred embodiment of the present invention also has, and the ambient temperature of sealing up for safekeeping in the described step 3 of the mould processing technology of biological activity is 20 ℃～30 ℃, and is sealed up for safekeeping in the container of sealing lucifuge.
On the basis of above-described embodiment respectively to suffer from comedo, pollinosis, solar dermatitis, neurodermatitis,, beriberi, tinea, scald, red trauma.The patient of the various dermatosis such as repelling mosquito, skin pruritus has carried out usability treatment, specifically treats case as follows:
1, Liu Wenhui: when man, in April, 97 are medical 10 years old.Annual spring is because pollen hypersensitivity whole body is itched, whole skin quilt is scratched.Use this medicine treatment: spread after medicine less than 20 minutes, whole body has just no longer been itched, and second night is examined the state of an illness, and the skin of being scratched is all tied first, till now not recurrence.
2, farming family stays: when man, in April, 97 are medical 8 years old.Whole body has 27 place's diameters at 0.5 to 0.8 centimetre of red and swollen piece, and flowing water is broken at top, is variola after diagnosing.Use the treatment of this medicine to smear twice recovery from illness, so far not recurrence.
3, Liu Rui: when man, in April, 98 are medical 11 years old.Little erythema is very itched, had to whole body.In many families such as the People's Hospitals, Jiaozhuo, fail to respond to any medical treatment, and do not check out what anaphylactogen is.Use this medicine treatment time recovery from illness, so far not recurrence.
4, Geng Baowen: man, 99 years when medical 39 years old.Be diagnosed as neurodermatitis, both legs GrandTech itches and feels bad, and scratch skin many places, uses this medicine to treat twice healing, so far not recurrence.
5 monarchs Wang Yu: medical 58 years old of female, 2000.The long 3 centimetres of left and right sclerderm beriberi of diameter of the both feet heart, are used the treatment of this medicine to cure for 1 year nearly.
6, Zhao Quan: when man, calendar year 2001 are medical 15 years old.Comedo (acne) is used this medicine treatment recovery from illness in ten days.To not recurring to the present.
7, Liu Baizhan: man, 2002 are medical 55 years old.The long white tinea of shank, is used the treatment of this medicine once to cure, and recurrence for the second time, reuses the treatment of this medicine, effective.
8, Chai Qinying: female, 55 years old.Once repeatedly by oil, boiled water, scalded, and used this medicine therapeutic effect very good.Other relatives and friends use, so long as just spray this medicine after scalding, can in 30 minutes, fully recover.
9, inventor undergoes, and when wound, easily bleeds, and sprays after this medicine, can prevent wound infection, can promote wound healing again, and wound healing is not itched yet.
10, antipruritic: summer, mosquito was many every year, and everybody was stung by mosquito, as long as spray this medicine, itched and eliminated within 3 seconds, and within 2 to 3 hours, mosquito can not sting again.
The invention is not restricted to above-mentioned embodiment, those skilled in the art make to any apparent improvement of above-mentioned embodiment or change, can not exceed the protection domain of design of the present invention and claims.
Claims (10)
1. a dermatosis external medicinal liquid, it is characterized in that, the raw materials for production of described medicinal liquid comprise Fructus Lycopersici esculenti juice, biological activity is mould, antiseptic and Chinese crude drug, Fructus Lycopersici esculenti juice and biological activity are mould, the raw material of antiseptic is 100:4:1 by weight ratio, by every 4 liters by Fructus Lycopersici esculenti juice, in the mother solution that biological activity is mould and antiseptic is mixed with, add 0.8 kilogram of Chinese crude drug proportioning preparating liquid, described biological activity is mould is the bean corruption after fermentation, described antiseptic is sodium benzoate, in described medical material, press every 5 grams of Rhizoma Anemarrhenaes, 5 grams of Cortex Phellodendris, 4 grams of Cortex Moutans, 4 grams of Poria, 4 grams of Rhizoma Alismatis, 3 Keshan medicines, 3 grams of Fructus Evodiaes and 4 grams of Radix Rehmanniae are 1 part and are configured.
2. a preparation technology for dermatosis external medicinal liquid as claimed in claim 1, is characterized in that, described preparation technology comprises the steps:
Step 1, cleans Fructus Lycopersici esculenti to dry fragmentation;
Step 2 adds biological activity mould in Fructus Lycopersici esculenti, stirs, and makes fermentation Fructus Lycopersici esculenti;
Step 3, carries out slag, juice separation by the Fructus Lycopersici esculenti fermenting;
Step 4, is heated to boiling by isolated juice, again filters after cooling, and the juice after filtering is put into the container with seal cover, then to add antiseptic in container and stir after make mother solution;
Step 5, then Chinese crude drug is immersed in mother solution, then cover seal cover and seal up for safekeeping 7 to 10 days;
Step 6, deposits after 7 to 10 days the medicinal liquid of making after herbal medicine immersion is heated again, then filtering medicinal residues;
Step 7, by medicinal liquid bottling and encapsulation after filtering medicinal residues.
3. the preparation technology of dermatosis external medicinal liquid as claimed in claim 2, is characterized in that, in described step 3, the mould making step of biological activity comprises:
Step 1, is cut into 3 * 3 * 3 squares by bean curd;
Step 2, by the bean curd fermentation cutting 7 to 10 days;
Step 3, adds the Sal pressed compact that is no more than by weight percentage 5% in the bean curd after fermentation;
Step 4, adds 5% Alumen by weight percentage again by the good bean curd of pressed compact, then seals up for safekeeping 180 days～200 days.
4. the preparation technology of dermatosis external medicinal liquid as claimed in claim 2, is characterized in that, the ebuillition of heated temperature in described step 3 is 100 ℃, and described being cooled to is cooled to room temperature.
5. the preparation technology of dermatosis external medicinal liquid as claimed in claim 2, is characterized in that, the operation of squeezing the juice in described step 3 is to adopt pressure filter to carry out slag, juice separation.
6. the preparation technology of dermatosis external medicinal liquid as claimed in claim 2, is characterized in that, the Chinese crude drug in described step 5 soaks in mother solution at normal temperatures.
7. the preparation technology of dermatosis external medicinal liquid as claimed in claim 2, is characterized in that, in described step 6, the temperature of heating is 100 ℃ again, and the time of heating is 5～10 minutes.
8. the preparation technology of dermatosis external medicinal liquid as claimed in claim 2, is characterized in that, the Chinese crude drug in described step 5 was graininess by its pulverizing before soaking.
9. the preparation technology of dermatosis external medicinal liquid as claimed in claim 3, is characterized in that, in described step 2, the ambient temperature of bean curd fermentation is 20 ℃～30 ℃, and ambient humidity is 70%～80%, and fermentation process is natural fermentation.
10. the preparation technology of dermatosis external medicinal liquid as claimed in claim 3, is characterized in that, the ambient temperature that described step 3 is sealed up for safekeeping is 20 ℃～30 ℃, and is sealed up for safekeeping in the container of sealing lucifuge.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410476990.6A CN104189414A (en) | 2014-09-18 | 2014-09-18 | External liquid medicine for skin diseases and preparation technology thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410476990.6A CN104189414A (en) | 2014-09-18 | 2014-09-18 | External liquid medicine for skin diseases and preparation technology thereof |
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| CN104189414A true CN104189414A (en) | 2014-12-10 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107441158A (en) * | 2017-08-11 | 2017-12-08 | 荆门市东宝区化金生物制品厂 | One kind is treated deep skin and festered（Diabetic complication）Exempt from the decoction and manufacture skill of amputation |
| CN110101760A (en) * | 2019-05-15 | 2019-08-09 | 山西大学 | A kind of Chinese herbal medicine for external use and its liquid-state fermentation technology |
Citations (2)
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| KR20010076516A (en) * | 2000-01-26 | 2001-08-16 | 성재갑 | Compositions containing extract of anemarrhena asphodeloides |
| CN102772339A (en) * | 2012-08-20 | 2012-11-14 | 刘伯堂 | Light-yellow transparent concentrated tomato waste liquid and preparation method and application thereof |
-
2014
- 2014-09-18 CN CN201410476990.6A patent/CN104189414A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010076516A (en) * | 2000-01-26 | 2001-08-16 | 성재갑 | Compositions containing extract of anemarrhena asphodeloides |
| CN102772339A (en) * | 2012-08-20 | 2012-11-14 | 刘伯堂 | Light-yellow transparent concentrated tomato waste liquid and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 国家中医药管理局专业技术资格考试专家委员会编写: "《全国中医药专业技术资格考试大纲与细则 中医皮肤与性病专业》", 31 December 2011 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107441158A (en) * | 2017-08-11 | 2017-12-08 | 荆门市东宝区化金生物制品厂 | One kind is treated deep skin and festered（Diabetic complication）Exempt from the decoction and manufacture skill of amputation |
| CN110101760A (en) * | 2019-05-15 | 2019-08-09 | 山西大学 | A kind of Chinese herbal medicine for external use and its liquid-state fermentation technology |
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