CN114515324A - Traditional Chinese medicine epidemic prevention aromatherapy composition and product thereof - Google Patents

Traditional Chinese medicine epidemic prevention aromatherapy composition and product thereof Download PDF

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CN114515324A
CN114515324A CN202111407258.XA CN202111407258A CN114515324A CN 114515324 A CN114515324 A CN 114515324A CN 202111407258 A CN202111407258 A CN 202111407258A CN 114515324 A CN114515324 A CN 114515324A
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chinese medicine
traditional chinese
incense
epidemic
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张炜
魏玉辉
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First Hospital of Lanzhou University
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Abstract

The invention provides a traditional Chinese medicine epidemic prevention aromatherapy composition and various aromatherapy products prepared from the same, wherein the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials: rhubarb, rhizoma atractylodis, angelica dahurica, rhizoma kaempferiae, white plum blossom, rose, albizia flower, sandalwood, nardostachyos root and rhizome, tree peony bark, fennel and dalbergia wood. The traditional Chinese medicine aromatherapy composition has the effects of killing, inhibiting bacteria, calming nerves and relieving depression, has high antibacterial activity, has a good prevention effect on the novel coronavirus infection pneumonia, can achieve the purposes of preventing and treating diseases in the bud and preventing diseases, can also calm nerves and calm nerves, relax mood, and relieve mental stress and emotional depression caused by epidemic diseases; the raw materials are easy to obtain, the preparation method is simple, the use is convenient, the irritation is small, and no side effect is caused.

Description

Traditional Chinese medicine epidemic prevention aromatherapy composition and product thereof
Technical Field
The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine epidemic prevention aromatherapy composition and a product thereof.
Background
The new type of coronavirus infection pneumonia is a rapid-circulating, large-harm acute infectious pneumonia, and the pathogen of the pneumonia is a new type of coronavirus which is not found in human before. The epidemic must have the following three basic links: the source of infection, the route of transmission and the susceptible population. Without any of these links, it is unlikely to become popular.
From the perspective of traditional Chinese medicine, the novel coronavirus pneumonia belongs to the category of epidemic diseases in traditional Chinese medicine, is an acute infectious disease transmitted through respiratory tracts, and belongs to the class of diseases with strong infectivity, critical and violent illness state and pandemic characteristics in epidemic diseases. The pathogenesis is 'feeling the qi of plague crime', the syndrome differentiation is 'cold-dampness (plague) plague', which is caused by feeling the cold-dampness plague. The Huangdi's classic on medicine states that: the five epidemic diseases are all easy to infect and similar in symptoms without any question of size. Therefore, it is suitable to treat cold pathogen by pungent and warm exterior syndrome relieving, and damp pathogen by aromatic pathogen to avoid foul and eliminate turbid.
For infectious diseases, ancient Chinese medicine emphasizes the importance of prevention, and prevents the occurrence of the diseases by fumigating or wearing medicines. The fumigation and disinfection epidemic prevention method has the characteristics of simple and convenient method, easily obtained medicines, safe use, ideal effect and the like, and is easy to popularize and apply. And can avoid the defects of strong disinfection and stimulation of ultraviolet rays, peroxyacetic acid and chlorine-containing disinfectants and easy damage to skin and mucous membranes.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine epidemic prevention aromatherapy composition and an aromatherapy product prepared from the composition aiming at the defects in the prior art.
Therefore, the invention adopts the following technical scheme:
a traditional Chinese medicine epidemic prevention aromatherapy composition comprises the following traditional Chinese medicine raw materials:
rhubarb, rhizoma atractylodis, angelica dahurica, rhizoma kaempferiae, white plum blossom, rose, albizia flower, sandalwood, nardostachyos root and rhizome, tree peony bark, fennel and dalbergia wood.
The traditional Chinese medicine epidemic prevention aromatherapy composition comprises the following raw materials in parts by weight:
3-5 parts of rheum officinale, 5-8 parts of rhizoma atractylodis, 3-5 parts of radix angelicae, 2-5 parts of rhizoma kaempferiae, 5-8 parts of white plum blossom, 5-8 parts of rose, 5-8 parts of flos albiziae, 3-6 parts of sandalwood, 3-8 parts of nardostachyos root and rhizome, 3-6 parts of moutan bark, 3-8 parts of fennel and 4-8 parts of dalbergia wood.
Various aromatherapy products can be prepared by the traditional Chinese medicine epidemic prevention aromatherapy composition, and comprise incense, electric incense liquid, electric incense pieces, spray, sachet and the like.
In the formula, rheum officinale, rhizoma atractylodis, radix angelicae and rhizoma kaempferiae form an epidemic prevention formula which mainly has the effects of disinfection, sterilization, epidemic prevention and disease treatment, and the raw material medicines of the melancholy dispelling formula which is formed by flos pruni mume, rose, flos albiziae, sandalwood, nardostachys root and rhizome, cortex moutan, fennel and rosewood have aromatic odor, and the melancholy dispelling formula has the effects of clearing away the heart-fire and soothing the nerves, has the effects of bacteriostasis and epidemic prevention and soothing the nerves and dispelling the melancholy, can calm and help sleep, and can effectively relieve the emotional tension, depression and the like brought during the epidemic situation.
In the epidemic prevention formula, rhubarb purges fire toxin, resists bacteria and diminishes inflammation; rhizoma Atractylodis can remove dampness to stop pestilence and pathogenic toxin; the angelica dahurica is pungent, warm, fragrant, and has the effects of disinfection and bacteriostasis; kaempferia pungent and warm in property, aversion to miasma and aversion to qi, and cholera due to cold-dampness. Has effects of clearing away heat and toxic materials, eliminating pathogenic factors, sterilizing, preventing and treating diseases.
The raw materials of the depression relieving formula comprise:
white plum blossom: originally recorded in Ben Cao gang mu, it has the actions of soothing liver-qi stagnation, harmonizing stomach and promoting the production of body fluid. Fragrant, moving qi, resolving phlegm and resolving masses, it is known as decoction piece new reference: the flos Pruni mume has effects of calming liver and regulating stomach, and relieving epigastric pain and dizziness, and can be taken as diet. "Baihua mirror": appetizing and eliminating evil, cooking porridge and eating, promoting the rising of qi of clearing yang, steaming dew point tea, promoting the production of body fluid to quench thirst, relieving summer heat and relieving restlessness. Can be used for treating dysphoria, depression, neurasthenia, globus hystericus, and laryngopharynx discomfort due to emotional discomfort, stagnation of liver-qi, and phlegm-qi stagnation.
And (3) rose: it is warm in nature, sweet in taste and slightly bitter in flavor, enters liver and spleen meridians, has faint scent, can sooth liver, regulate qi and relieve depression, and is mainly indicated for liver qi stagnation, chest stuffiness and pain, incoordination between liver and stomach, abdominal distention and pain, belching with ease. Strong fragrance, clear but not turbid, mild but not violent, liver softening, stomach awakening, qi flowing, blood circulation promoting, suffocation dredging, no pungent, warm and hard-dry disadvantages, and the most excellent.
Albizzia flower: sweet and neutral in taste, contains albizin and tannin, and has the effects of resolving stagnation, tranquilizing mind, nourishing yin, tonifying yang, clearing liver and improving eyesight. Can calm central nerve, help sleep, and relieve adverse mood such as depression and anxiety. The albizia flower can nourish five internal organs, harmonize mind, beautify skin, has better effects of strengthening body, tranquilizing, calming nerves, beautifying and the like, and is a good product for treating neurasthenia.
The three flower raw materials have the functions of soothing liver and relieving depression and benefiting heart and will be better in overall efficacy by being matched with sandalwood, fennel, dalbergia wood and nardostachyos to play the roles of smoothing qi activity in vivo and enabling body fluid to run normally, and being matched with moutan bark which has the functions of clearing liver and improving vision and dispersing and dissolving stasis. In order to avoid excessive dryness of the fragrance, jujube paste (jujube pulp paste of jujube) can be added into the formula for neutralizing dryness of the depression-relieving formula.
The invention has the beneficial effects that:
the traditional Chinese medicine aromatherapy composition has the effects of killing, inhibiting bacteria, calming nerves and relieving depression, has high antibacterial activity, has a good prevention effect on the novel coronavirus infection pneumonia, can achieve the purposes of preventing and treating diseases in the bud and preventing diseases, can also calm nerves and calm nerves, relax mood, and relieve mental stress and emotional depression caused by epidemic diseases; the raw materials are easy to obtain, the preparation method is simple, the use is convenient, the irritation is small, and no side effect is caused; the system can be widely applied to public places such as hospitals, stations, office areas and the like, families, transportation means and the like, and is more suitable for modern people in terms of safety and convenience; it can also be used for preventing other respiratory infectious diseases.
Detailed Description
The scheme of the invention is further illustrated by the following specific examples.
Example 1: preparation of traditional Chinese medicine epidemic prevention incense
The traditional Chinese medicine comprises the following raw materials: 3 parts of rheum officinale, 5 parts of rhizoma atractylodis, 5 parts of radix angelicae, 3 parts of rhizoma kaempferiae, 5 parts of prunus mume, 6 parts of rose, 6 parts of albizia flower, 3 parts of sandalwood, 5 parts of nardostachyos root and rhizome, 5 parts of moutan bark, 5 parts of fennel, 4 parts of dalbergia wood and 7 parts of jujube paste.
Auxiliary materials: charcoal powder (combustion improver) and elm bark powder (adhesive).
The preparation method comprises the following steps: pulverizing the above materials by micronization, sieving with 100 mesh sieve, adding charcoal powder 100g and elm bark powder 50g per 100g of Chinese medicinal powder, adding water 2 times the weight of the mixed materials, stirring into paste, extruding in a press molding machine, demolding, oven drying, and packaging. The incense can be made into linear shape, disc shape, tower shape, etc. according to the requirement.
Example 2: preparation of traditional Chinese medicine epidemic prevention electric fumigation liquid
The traditional Chinese medicine comprises the following raw materials: 4 parts of rheum officinale, 8 parts of rhizoma atractylodis, 3 parts of angelica dahurica, 2 parts of rhizoma kaempferiae, 6 parts of prunus mume, 8 parts of rose, 5 parts of albizia flower, 5 parts of sandalwood, 8 parts of nardostachyos root and rhizome, 6 parts of moutan bark, 8 parts of fennel and 6 parts of dalbergia wood.
The preparation method comprises the following steps:
1) taking the traditional Chinese medicine raw materials according to the weight ratio, adding 75% vol ethanol, adding 1000ml of ethanol into every 100g of the traditional Chinese medicine raw materials, standing and extracting for 24 hours;
2) filtering to obtain filtrate, and measuring the dry extract rate and the ethanol concentration, wherein the dry extract rate is qualified standard: 20-30%, and qualified ethanol concentration standard: 60-75% vol;
3) concentration: concentrating the filtered ethanol extractive solution to 40-60% of the original volume under heating in water bath, adding appropriate amount of antiseptic, and bottling.
The using method comprises the following steps:
similar to the electric mosquito repellent liquid, the incense liquid bottle is connected with an electric mosquito repellent liquid heater for heating and volatilizing.
Example 3: preparation of Chinese medicine epidemic prevention electric heating incense tablet
The traditional Chinese medicine comprises the following raw materials: 5 parts of rheum officinale, 6 parts of rhizoma atractylodis, 4 parts of radix angelicae, 5 parts of rhizoma kaempferiae, 8 parts of prunus mume, 5 parts of rose, 8 parts of albizia flower, 6 parts of sandalwood, 3 parts of nardostachyos root and rhizome, 3 parts of moutan bark, 3 parts of fennel, 8 parts of dalbergia wood and 6 parts of jujube paste.
The preparation method comprises the following steps:
mixing the medicinal materials in proportion, pulverizing, sieving with 60 mesh sieve, loading into a percolating tube, adding 10 times of 75% ethanol, standing overnight, percolating and extracting at a flow rate of 2 ml/min, collecting percolate, recovering ethanol under reduced pressure, adding vanillin (final mass concentration of vanillin is 2%) into the concentrated solution to obtain dripping liquid of incense tablet (each 1ml of medicinal liquid is 5g of raw medicinal material), collecting 2ml of dripping liquid, soaking into cellulose or porous blank carrier made of cellulose or diatomite, and air drying.
The using method comprises the following steps:
similar to the electric mosquito repellent incense tablet, the Chinese medicinal epidemic prevention electric incense tablet is placed on an electric mosquito repellent incense tablet heater to be heated and volatilized.
Example 4: preparation of Chinese medicine epidemic prevention spray
The traditional Chinese medicine comprises the following raw materials: 5 parts of rheum officinale, 6 parts of rhizoma atractylodis, 3 parts of angelica dahurica, 3 parts of rhizoma kaempferiae, 6 parts of white plum blossom, 6 parts of rose, 8 parts of flos albiziae, 5 parts of sandalwood, 3 parts of nardostachyos root and rhizome, 5 parts of moutan bark, 6 parts of fennel and 6 parts of rosewood.
The preparation method comprises the following steps:
1) taking the traditional Chinese medicine raw materials according to the weight ratio, adding 75% vol ethanol, adding 1000ml of ethanol into every 100g of the traditional Chinese medicine raw materials, standing and extracting for 24 hours;
2) filtering, collecting filtrate, diluting the filtrate with distilled water by 2-4 times, bottling, and adding valve cap.
The using method comprises the following steps:
like alcohol disinfectant spray, it can be sprayed on environment or skin.
Example 5: preparation of Chinese medicine antiepidemic sachet
The traditional Chinese medicine comprises the following raw materials: 4 parts of rheum officinale, 6 parts of rhizoma atractylodis, 5 parts of angelica dahurica, 3 parts of rhizoma kaempferiae, 6 parts of white plum blossom, 8 parts of rose, 6 parts of flos albiziae, 6 parts of sandalwood, 5 parts of nardostachyos root and rhizome, 5 parts of moutan bark, 6 parts of fennel, 6 parts of dalbergia wood and 8 parts of jujube paste.
The preparation method comprises the following steps:
taking the traditional Chinese medicine raw materials according to the weight ratio, crushing, sieving by a 60-mesh sieve, and filling the medicinal powder into a cloth bag.
The using method comprises the following steps:
the perfume bag can be placed at home, indoors, bed curtain or in a car, or worn on chest or waist, the fragrance of the perfume bag can be maintained for about three months, and a small amount of perfume can be burned for use after the fragrance is weakened. It is forbidden for pregnant women and patients allergic to aromatic drugs.
In order to further verify the antibacterial and epidemic prevention effects of the traditional Chinese medicine epidemic prevention aromatherapy composition, the invention adopts the following steps of example 4: the Chinese medicine epidemic prevention spraying agent is taken as an example, and antibacterial activity experiments are carried out. The experimental contents are as follows:
firstly, in order to verify the influence of extraction time and dilution times on the extraction effect, namely the influence on the concentration of emodin and chrysophanol in an extracting solution, 100g of traditional Chinese medicine raw materials are added into 1000ml of ethanol, extraction is respectively carried out according to the concentration of 75% and 95% of ethanol and the extraction time of 24h and 48h, the extracting solution is diluted by 2 times of distilled water to obtain an experimental sample, and 25ml of each sample is taken. The label is: sample 1 (95% ethanol, extraction time 24 h), sample 2 (95% ethanol, extraction time 48 h), sample 3 (75% ethanol, extraction time 24 h), sample 4 (75% ethanol, extraction time 48 h).
TABLE 1 sample extraction rate, emodin and chrysophanol content
Figure 80776DEST_PATH_IMAGE001
The results show that the extraction rate of the sample, the content of emodin and chrysophanol are as follows according to different extraction processes from large to small: extracting with 75% ethanol for 24h and about 75% ethanol for 48h>95% ethanol extraction 24h ≈ 95% ethanol extraction 48h (Table 1). The different extraction times did not have a significant effect on the extraction yield (P=0.459 > 0.05), and the ethanol concentration has a significant effect on the extraction yield: (P< 0.001), no interaction between extraction time and ethanol concentration: (P=0.854 > 0.05). In addition, the extraction time and the ethanol concentration have no obvious influence on the content of the emodin and the chrysophanol, and no interaction exists between the extraction time and the ethanol concentration.
Considering that the sample contains ethanol, the same concentration of ethanol is used for effect comparison, and the experimental sample is set as follows:
experimental groups: extracting the traditional Chinese medicine raw materials by 75% ethanol for 24 hours, and diluting the extracting solution by 2 times to obtain a product; control group 1: 37.5% ethanol, control 2: 18.75% ethanol; the amount of each sample was the same.
The antibacterial effect is measured by adopting a liquid quantitative suspension test method, and the experimental process of the liquid quantitative suspension test method comprises the following steps: the sample is diluted to 20% concentration by trypticase soy peptone liquid medium, 1mL of the screened sample is respectively added into a test tube, 0.1 mL of bacterial suspension with different concentrations (103, 104, 105 and 106 cfu/mL) is respectively added, the trypticase soy peptone liquid medium is used as a negative control, and the medium containing bacteria with corresponding concentrations is used as a positive control. Culturing at 35 deg.C for 24h and 48h, and observing the growth status of bacteria in the test tube.
The experimental results are as follows:
TABLE 2 determination of the inhibitory Effect of the samples on 5 bacteria by the liquid quantitative suspension test method
Figure 794654DEST_PATH_IMAGE002
Figure 839971DEST_PATH_IMAGE003
Note: 1. "-" indicates clear, sterile growth of the liquid; 2. "+" indicates that the liquid was turbid and there was growth of bacteria.
Experiments prove that the bacteriostatic effect of experimental group samples is obviously higher than that of ethanol with the same concentration, and the traditional Chinese medicine epidemic prevention spray prepared by the invention has good bacteriostatic activity.

Claims (9)

1. The traditional Chinese medicine epidemic prevention aromatherapy composition is characterized by comprising the following traditional Chinese medicine raw materials:
rhubarb, rhizoma atractylodis, angelica dahurica, rhizoma kaempferiae, white plum blossom, rose, albizia flower, sandalwood, nardostachyos root and rhizome, tree peony bark, fennel and dalbergia wood.
2. The traditional Chinese medicine epidemic prevention aromatherapy composition according to claim 1, wherein the traditional Chinese medicine is prepared from the following raw materials in parts by weight:
3-5 parts of rheum officinale, 5-8 parts of rhizoma atractylodis, 3-5 parts of radix angelicae, 2-5 parts of rhizoma kaempferiae, 5-8 parts of white plum blossom, 5-8 parts of rose, 5-8 parts of flos albiziae, 3-6 parts of sandalwood, 3-8 parts of nardostachyos root and rhizome, 3-6 parts of moutan bark, 3-8 parts of fennel and 4-8 parts of dalbergia wood.
3. The traditional Chinese medicine epidemic prevention aromatherapy composition according to claim 2, characterized by further comprising 6-8 parts of jujube paste.
4. A Chinese medicinal incense for epidemic prevention, which is prepared from the Chinese medicinal incense composition for epidemic prevention of any one of claims 1 to 3, and conventional adjuvants for incense preparation.
5. The traditional Chinese medicine epidemic prevention incense of claim 4, wherein the incense comprises a line incense, a coil incense, a tower incense and incense powder.
6. A Chinese medicinal anti-epidemic incense liquid, which is characterized by being prepared from the Chinese medicinal anti-epidemic incense composition of any one of claims 1 to 3 by extracting and concentrating through an extraction process.
7. A Chinese medicinal anti-epidemic electric heating incense tablet is characterized by being prepared from the Chinese medicinal anti-epidemic incense composition of any one of claims 1 to 3 by extracting, concentrating and soaking.
8. A Chinese medicinal spray for preventing epidemic, which is characterized in that the Chinese medicinal spray is prepared from the Chinese medicinal composition for preventing epidemic according to any one of claims 1-3 by extracting and diluting.
9. A traditional Chinese medicine epidemic prevention sachet is characterized in that the sachet is prepared by bagging after the traditional Chinese medicine epidemic prevention aromatherapy composition of any one of claims 1 to 3 is prepared into powder or bagging after the traditional Chinese medicine epidemic prevention aromatherapy composition is directly mixed.
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