CN1089845A - A kind of oral medicine and medicine for external use and production method thereof for the treatment of bone disease - Google Patents

A kind of oral medicine and medicine for external use and production method thereof for the treatment of bone disease Download PDF

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CN1089845A
CN1089845A CN93100767A CN93100767A CN1089845A CN 1089845 A CN1089845 A CN 1089845A CN 93100767 A CN93100767 A CN 93100767A CN 93100767 A CN93100767 A CN 93100767A CN 1089845 A CN1089845 A CN 1089845A
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medicine
compound recipe
powder
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CN1059559C (en
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杨海浪
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Abstract

A kind of treatment bone disease is especially treated the combination herbal mixture of hyperosteogeny, comprising: the compound recipe of being made up of 20 flavor Chinese medicines such as Sanguis Draxonis, Fructus Lycii, Typhonium flagelliforme (Lodd.) Blume for oral administration and by Moschus, Camphora, system Squama Manis, Sanguis Draxonis etc. 27 externally used compound that Chinese medicines form of distinguishing the flavor of.It is for oral administration that compound recipe for oral administration can be made into medicated wine, powder, pill, capsule; Externally used compound can be made into externally used medicine bag and external baste.The external of two kinds of compound recipe oral administrations is used in combination, and also can use separately.

Description

A kind of oral medicine and medicine for external use and production method thereof for the treatment of bone disease
The application relates to a kind of medicine and production method thereof for the treatment of disease, especially a kind of Chinese medicine and medicine for external use for the treatment of hyperosteogeny.
Bone matrix hyperplasia claims bony spur again, is a kind of common bone disease.This disease is a feature with pathological changes joint hypertrophy, and modern medicine is called the skeleton degeneration.Bone matrix hyperplasia mostly occurs at the prudent position of cervical vertebra, lumbar vertebra and extremities joint.Suffer from this after being ill, the joint hyperplasia of being injured, limitation of activity, the muscles and bones muscle acid heavy pain that expands, moving then aggravation or twinge cause that gradually numb limbs and tense tendons paralyses, until disability.
The application's purpose is to disclose a kind of effective in cure to various bone diseases, especially to the specific Chinese medicine for oral administration of hyperosteogeny and external Chinese medicine and production method thereof.
The application's content is that to make medicated wine, powder, pill, capsule with combination herbal mixture agent for oral administration, or makes medicated bag, smears the liquor external with making up the herbal mixture agent.This combination compound preparation is the Therapeutic Principle according to motherland's medical science " flat invigorating the liver and kidney, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral ", with reach " healthy energy foot, stasis of blood resistance logical and not bitterly " therapeutic purposes.
The application's combination compound recipe has two kinds, and combination compound recipe 1 is an oral medicine, and combination compound recipe 2 is a medicine for external use.Below openly make up the composition of compound recipe 1, combination compound recipe 2, the weight range and the best compositing formula of each composition in the percentage by weight of each composition, every dose of medicine with the form of form.
The table I is the composition and the content ratio of combination compound recipe 1.
The table II is the composition and the content ratio of combination compound recipe 2.
The component content and the most preferred embodiment component of table I combination compound recipe 1
Numbering Composition Percentage composition % Every dose of medicine composition amount (g) Optimum formula amount g
1 Sanguis Draxonis 7.75-11.63 16-24 20
2 Olibanum (processed) 7.04-10.50 14.4-21.6 18
3 Myrrha (processed) 7.04-10.50 14.4-21.6 18
4 Fructus Lycii 4.65-6.98 9.6-14.4 12
5 Typhonium flagelliforme (Lodd.) Blume 9.74-14.54 20-30 25
6 The system Zaocys 3.88-5.82 8-12 10
7 Moschus 0.12-0.17 0.24-0.36 0.3
8 The system Squama Manis 5.82-8.73 12-18 15
9 Roasted RADIX PUERARIAE 5.82-8.73 12-18 15
10 Radix Clematidis 5.82-8.73 12-18 15
11 Niu Xi (processed with wine) 3.88-5.82 8-12 10
12 Radix Paeoniae Alba (parched) (wine) 5.82-8.73 12-18 15
13 Scorpio 1.94-2.91 4-6 5
14 Scolopendra 1.94-2.91 4-6 5
15 Flos Carthami 1.94-2.91 4-6 5
16 The system vomiting nut 0.39-0.58 0.8-1.2 1
17 Pyritum (processed) 0.78-1.16 1.6-2.4 2
18 The system Os Tigris 1.16-1.75 2.4-3.6 3
19 Radix Aconiti Preparata 2.33-3.49 4.8-7.2 6
20 Eupolyphaga Seu Steleophaga 2.33-3.49 4.8-7.2 6
Add up to 80.19-119.08 165.04-247.56 206.3
The component content of table II combination compound recipe 2 and the best prescription of implementing
Numbering Composition Percentage composition % Every dose of medicine composition amount (g) Optimum formula amount g
1 Moschus 0.08-0.13 1.6-2.4 2
2 Sanguis Draxonis 2.17-3.26 40-60 50
3 The steeping in wine Venenum Bufonis 0.22-0.33 4-6 5
4 Pyritum (processed) 2.17-3.26 40-60 50
5 Camphora 2.17-3.26 40-60 50
6 The system Squama Manis 2.17-3.26 40-60 50
7 Os pardi 2.17-3.26 40-60 50
8 Typhonium flagelliforme (Lodd.) Blume 4.34-6.5 80-120 100
9 Roasted RADIX PUERARIAE 4.34-6.5 80-120 100
10 Radix Clematidis 8.68-13.03 160-240 200
11 Olibanum (processed) 2.17-3.26 40-60 50
12 Daphne giraldii Nitsche 17.37-26.06 320-480 400
13 China's Herba Asari 2.17-3.26 40-60 50
14 Rhizoma Et Radix Notopterygii 2.17-3.26 40-60 50
15 Radix Aconiti Preparata 4.34-6.5 30-120 100
16 Rhizoma Pinelliae Preparata 2.17-3.26 40-60 50
17 The Radix Angelicae Dahuricae 2.17-3.26 40-60 50
18 Rhizoma Curcumae Longae 2.17-3.26 40-60 50
19 Climing he trailing plants 0.43-0.65 8-12 10
20 The system vomiting nut 1.08-1.63 20-30 25
21 The Radix Aucklandiae 2.17-3.26 40-60 50
22 Rhizoma Arisaematis 2.17-3.26 40-60 50
23 Pollen Typhae 2.17-3.26 40-60 50
24 Oletum Trogopterori 2.17-3.26 40-60 50
25 Flos Carthami 2.17-3.26 40-60 50
26 Myrrha (processed) 2.17-3.26 40-60 50
27 Eupolyphaga 2.17-3.26 40-60 50
Add up to 79.94-119.98 1473.6-2210.4 1842.0
Combination compound recipe 1 when making medicated wine its method be that the 19 flavor Chinese medicine mixed powders of all the other except that Moschus in the combination compound recipe 1 are broken into coarser powder, and the Chinese liquor of spending with 45 degree-60 are solvent, the medicated wine ratio is 1: 5-10.Medicated wine mixing room temperature lower seal infuse is about ten days, and heat decocts boiling 15-30 minute every Tonga, and filter and remove residue adds Moschus in this wine liquid more in proportion, the mixing bottling, and sealing and standing can be standby about ten days.
When combination compound recipe 1 was made powder, its method was that various components are ground into powder (crossing the above sieve of 100 orders), is mixed into powder then, according to the clinical application effective dose, can directly draw away mixing in water for oral taking with yellow wine, and said preparation can be for not alcoholic patient use.
When combination compound recipe 1 is made pill-type, its method is that the plant medicine material in the combination compound recipe 1 is fried in shallow oil the dried powder (crossing the sieve more than 100 orders) that juice is condensed into dry extract through immersion, again with remaining animal fat pulverizing medicinal materials powdered (crossing 100 orders) with top sieve, again with the two mix homogeneously, with Chinese liquor, rice vinegar half and half, medicine juice is an excipient, make the ball shape, in order to taking, the said preparation volume is little, active ingredient height (suitable crude drug in whole 3 grams of the every gram of concentrated dry powder), it is lasting to absorb the slow efficacy of a drug, be applicable to the chronic disease use, take easily, easy to carry.
When the making capsule was for oral administration in the combination compound recipe 1, its method was that the mixing concentrate drying powder of pill agent is made capsule with machinery.
Combination compound recipe 1 every dose of medicine is a course of treatment, takes medicine each course of treatment 20 days, and general patient has three courses of treatment can produce effects and healing.Divide early, middle and late three one after each meals every day.Medicated wine is directly drunk, and pill, medicamental pulverata powder, available yellow wine are done to draw to take.
Combination compound recipe 2 is a kind of especially medicine for external use of hyperosteogeny of bone disease for the treatment of, and concrete composition and formula ratio see Table II.
When combination compound recipe 2 is made externally used medicine bag, its method is to be that coarser powder is crossed 12 mesh sieves with each flavor medicine pulverize separately, behind the mix homogeneously, the cloth bag of packing into seals standby, during use, impregnated in the medicated bag inner face with Chinese liquor or vinegar, spread on the affected part, medicated bag is outer can to add hot water bag, and every day, external application twice, each 30 to 60 minutes.This bag useful life is one month.
The method of making the external baste with combination compound recipe 2 is that the medicine of respectively distinguishing the flavor of in the combination compound recipe 2 is extracted with the water alcohol method dissolving respectively, is mixed and made into baste, and this baste can directly be applied to various bone disease affected parts, plays therapeutical effect.
The application's combination compound recipe has the effect of flat invigorating the liver and kidney, adjusting negative and positive and blood blood stasis dispelling, dispelling wind and removing obstruction in the collateral, reducing swelling and alleviating pain, strong muscles and bones, the circulation of the body of promotion inner blood is arranged, increase the heart and brain flow, reduce and reduce oxygen consumption, strengthen metabolism and human body resistivity, suppress and prevent the effect of hyperosteogeny pathological changes expansion, and reach the healing purpose.
The application's combination compound recipe cures mainly cervical vertebra, lumbar vertebra, thoracic vertebra and bones of limbs hyperosteogeny.Quadriplegia and anti-other hamartoplasia (as cyclomastopathy) of anti-cancerous protuberance that Fengshi Guanjie pain, soft tissue injury, control brain cardiovascular disease are caused also have significant curative effect.
Two kinds of combination herbal mixtures oral administration, externals when treatment combine, and also can use separately.

Claims (7)

1, a kind of combination herbal mixture for oral administration for the treatment of bone disease, this medicine can be made medicated wine, powder, pill, capsule form, it is characterized in that, and the component of this Chinese medicine is the listed content of following table:
The component content and the most preferred embodiment component of table I combination compound recipe 1 Numbering Composition Percentage composition % Every dose of medicine composition amount (g) Optimum formula amount g 1 Sanguis Draxonis 7.75-11.63 16-24 20 2 Olibanum (processed) 7.04-10.50 14.4-21.6 18 3 Myrrha (processed) 7.04-10.50 14.4-21.6 18 4 Fructus Lycii 4.65-6.98 9.6-14.4 12 5 Typhonium flagelliforme (Lodd.) Blume 9.74-14.54 20-30 25 6 The system Zaocys 3.88-5.82 8-12 10 7 Moschus 0.12-0.17 0.24-0.36 0.3 8 The system Squama Manis 5.82-8.73 12-18 15 9 Roasted RADIX PUERARIAE 5.82-8.73 12-18 15 10 Radix Clematidis 5.82-8.73 12-18 15 11 Niu Xi (processed with wine) 3.88-5.82 8-12 10 12 Radix Paeoniae Alba (parched) (wine) 5.82-8.73 12-18 15 13 Scorpio 1.94-2.91 4-6 5 14 Scolopendra 1.94-2.91 4-6 5 15 Flos Carthami 1.94-2.91 4-6 5 16 The system vomiting nut 0.39-0.58 0.8-1.2 1 17 Pyritum (processed) 0.78-1.16 1.6-2.4 2 18 The system Os Tigris 1.16-1.75 2.4-3.6 3 19 Radix Aconiti Preparata 2.33-3.49 4.8-7.2 6 20 Eupolyphaga Seu Steleophaga 2.33-3.49 4.8-7.2 6 Add up to 80.19-119.08 165.04-247.56 206.3
2, Chinese medicine compound as claimed in claim 1, it is characterized in that the method for making medicated wine is, except that Moschus all the other Chinese medicine mixed powder in the compound recipe is broken into coarser powder, and with 45 the degree-60 the degree Chinese liquor be solvent, the medicated wine ratio is 1: 5-10, medicated wine mixing room temperature lower seal infuse is about ten days, heat decocts boiling 15-30 minute every Tonga, filter and remove residue adds Moschus in the wine liquid more in proportion, and sealing and standing got final product about ten days.
3, Chinese medicine compound as claimed in claim 1, the method that it is characterized in that making powder are the various components in the compound recipe to be ground into powder cross sieve more than 100 orders, are mixed into powder then.
4, Chinese medicine compound as claimed in claim 1, the method that it is characterized in that making pill is the plant medicine material in the compound recipe to be fried in shallow oil the dried powder that juice is condensed into dry extract through immersion cross 100 orders with top sieve, again remaining animal fat pulverizing medicinal materials powdered is crossed 100 orders with top sieve, with the two mix homogeneously, with Chinese liquor, rice vinegar half and half, add excipient (medicine juice), make the ball shape.
5, a kind of external combination herbal mixture for the treatment of bone disease, this medicine can be made externally used medicine bag, the external baste, the component that it is characterized in that this Chinese medicine is the listed content of following table:
The component content of table II combination compound recipe 2 and the best prescription of implementing Numbering Composition Percentage composition % Every dose of medicine composition amount (g) Optimum formula amount g 1 Moschus 0.08-0.13 1.6-2.4 2 2 Sanguis Draxonis 2.17-3.26 40-60 50 3 The steeping in wine Venenum Bufonis 0.22-0.33 4-6 5 4 Pyritum (processed) 2.17-3.26 40-60 50 5 Camphora 2.17-3.26 40-60 50 6 The system Squama Manis 2.17-3.26 40-60 50 7 Os pardi 2.17-3.26 40-60 50 8 Typhonium flagelliforme (Lodd.) Blume 4.34-6.5 80-120 100 9 Roasted RADIX PUERARIAE 4.34-6.5 80-120 100 10 Radix Clematidis 8.68-13.03 160-240 200 11 Olibanum (processed) 2.17-3.26 40-60 50 12 Daphne giraldii Nitsche 17.37-26.06 320-480 400 13 China's Herba Asari 2.17-3.26 40-60 50 14 Rhizoma Et Radix Notopterygii 2.17-3.26 40-60 50 15 Radix Aconiti Preparata 4.34-6.5 30-120 100 16 Rhizoma Pinelliae Preparata 2.17-3.26 40-60 50 17 The Radix Angelicae Dahuricae 2.17-3.26 40-60 50 18 Rhizoma Curcumae Longae 2.17-3.26 40-60 50 19 Climing he trailing plants 0.43-0.65 8-12 10 20 The system vomiting nut 1.08-1.63 20-30 25 21 The Radix Aucklandiae 2.17-3.26 40-60 50 22 Rhizoma Arisaematis 2.17-3.26 40-60 50 23 Pollen Typhae 2.17-3.26 40-60 50 24 Oletum Trogopterori 2.17-3.26 40-60 50 25 Flos Carthami 2.17-3.26 40-60 50 26 Myrrha (processed) 2.17-3.26 40-60 50 27 Eupolyphaga 2.17-3.26 40-60 50 Add up to 79.94-119.98 1473.6-2210.4 1842.0
6, combination compound recipe as claimed in claim 5 is characterized in that with its method of making externally used medicine bag it being to be coarser powder with the medicine pulverize separately of respectively distinguishing the flavor of in the compound recipe, crosses 12 mesh sieves, and the cloth bag of packing into behind the mix homogeneously seals standby.
7, combination compound recipe as claimed in claim 5 is characterized in that with its method of making the external baste it being that the medicine of respectively distinguishing the flavor of in the combination compound recipe is extracted the mixing manufacture baste with the water alcohol method dissolving respectively.
CN93100767A 1993-01-07 1993-01-07 Oral medicine and external-use medicine for curing osteonosus and processing method thereof Expired - Fee Related CN1059559C (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550443A (en) * 2013-10-18 2014-02-05 淄博职业学院 Outer application preparation for treating meniscus athletic injury and preparation method thereof
CN103550319A (en) * 2013-10-18 2014-02-05 淄博职业学院 Outer application preparation for treating knee athletic injury and preparation method thereof
CN104491346A (en) * 2014-12-16 2015-04-08 黄向业 Traditional Chinese medicine for treating hyperostosis in oral administration and external application
CN105582244A (en) * 2016-01-21 2016-05-18 何茂武 Traditional Chinese medicine composition for treating lumbar vertebrae paralysis disease
CN106491887A (en) * 2016-12-05 2017-03-15 张长友 A kind of neck waist health rehabilitation paste and preparation method thereof
CN106620093A (en) * 2016-12-06 2017-05-10 吴瑞超 Medicine for treating cervical spondylosis and lumbar disc herniation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1051674A (en) * 1990-05-10 1991-05-29 左建平 The prescription of spur-subsiding pill and manufacture method

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550443A (en) * 2013-10-18 2014-02-05 淄博职业学院 Outer application preparation for treating meniscus athletic injury and preparation method thereof
CN103550319A (en) * 2013-10-18 2014-02-05 淄博职业学院 Outer application preparation for treating knee athletic injury and preparation method thereof
CN103550443B (en) * 2013-10-18 2015-11-25 淄博职业学院 The externally applied formulation for the treatment of meniscal sports injury and preparation method
CN104491346A (en) * 2014-12-16 2015-04-08 黄向业 Traditional Chinese medicine for treating hyperostosis in oral administration and external application
CN105582244A (en) * 2016-01-21 2016-05-18 何茂武 Traditional Chinese medicine composition for treating lumbar vertebrae paralysis disease
CN106491887A (en) * 2016-12-05 2017-03-15 张长友 A kind of neck waist health rehabilitation paste and preparation method thereof
CN106620093A (en) * 2016-12-06 2017-05-10 吴瑞超 Medicine for treating cervical spondylosis and lumbar disc herniation

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