CN1059559C

CN1059559C - Oral medicine and external-use medicine for curing osteonosus and processing method thereof

Info

Publication number: CN1059559C
Application number: CN93100767A
Authority: CN
Inventors: 杨海浪
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-01-07
Filing date: 1993-01-07
Publication date: 2000-12-20
Anticipated expiration: 2013-01-07
Also published as: CN1089845A

Abstract

The present invention relates to a combined compound traditional Chinese medicine for treating osteonosus, especially for treating hyperosteogeny. The traditional Chinese medicine comprises an oral-administration compound recipe and an external-administration compound recipe, wherein the oral-administration compound recipe comprises twelve kinds of traditional Chinese medicines: dragon blood, Chinese wolfberry, panax pseudo-ginseng and the like; the external-administration compound recipe comprises twenty-seven kinds of traditional Chinese medicines: musk, camphor, prepared putamen manidis, dragon blood, etc. The oral-administration compound recipe can be made into medicated liquor, medicinal powder, pills and capsules for oral administration, and the external-administration compound recipe can be made into external-administration medicament bags and external-administration painting liquid. The two kinds of compound recipes are used in a combination mode of oral administration and external administration, and can also be singly used.

Description

A kind of oral medicine and production method thereof for the treatment of bone disease

The application relates to a kind of medicine and production method thereof for the treatment of disease, especially a kind of Chinese medicine for the treatment of hyperosteogeny.

Bone matrix hyperplasia claims bony spur again, is a kind of common bone disease.This disease is a feature with pathological changes joint hypertrophy, and modern medicine is called the skeleton degeneration.Bone matrix hyperplasia mostly occurs at the prudent position of cervical vertebra, lumbar vertebra and extremities joint.Suffer from this after being ill, the joint hyperplasia of being injured, limitation of activity, the muscles and bones muscle acid heavy pain that expands, moving then aggravation or twinge cause that gradually numb limbs and tense tendons paralyses, until disability.

The application's purpose is to disclose a kind of effective in cure to various bone diseases, especially to specific Chinese medicine for oral administration of hyperosteogeny and production method thereof.

The application's content is that to make medicated wine, powder, pill, capsule with combination herbal mixture agent for oral administration.This combination compound preparation is the Therapeutic Principle according to motherland's medical science " flat invigorating the liver and kidney, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral ", with reach " healthy energy foot, stasis of blood resistance logical and not bitterly " therapeutic purposes.

The application's combination compound recipe is an oral medicine, and the weight range and the best compositing formula of each composition are as follows in the percentage by weight of composition, each composition of combination compound recipe, the every dose of medicine:

Every dose of medicine composition amount of component content percentage ratio % (g) optimum formula amount (g)

Sanguis Draxonis 7.75-11.63 16-24 20

Olibanum (processed) 7.04-10.50 14.4-21.6 18

Myrrha (processed) 7.04-10.50 14.4-21.6 18

Fructus Lycii 4.65-6.98 9.6-14.4 12

Typhonium flagelliforme (Lodd.) Blume 9.74-14.54 20-30 25

System Zaocys 3.88-5.82 8-12 10

Moschus 0.12-0.17 0.24-0.36 0.3

System Squama Manis 5.82-8.73 12-18 15

Roasted RADIX PUERARIAE 5.82-8.73 12-18 15

Radix Clematidis 5.82-8.73 12-18 15

Cattle sunset 3.88-5.82 8-12 10

Radix Paeoniae Alba (parched) 5.82-8.73 12-18 15

Scorpio 1.94-2.91 4-6 5

Scolopendra 1.94-2.91 4-6 5

Flos Carthami 1.94-2.91 4-6 5

System vomiting nut 0.39-0.58 0.8-1.2 1

Pyritum (processed) 0.78-1.16 1.6-2.4 2

System Os Tigris 1.16-1.75 2.4-3.6 3

Radix Aconiti Preparata 2.33-3.49 4.8-7.2 6

Eupolyphaga Seu Steleophaga 2.33-3.49 4.8-7.2 6

Add up to 80.19-119.08 165.04-247.56 206.3

The combination compound recipe when making medicated wine its method be that the 19 flavor Chinese medicine mixed powders of all the other except that Moschus in the combination compound recipe are broken into coarser powder, and the Chinese liquor of spending with 45 degree-60 are solvent, the medicated wine ratio is 1: 5-10.Medicated wine mixing room temperature lower seal infuse is about ten days, and heat decocts boiling 15-30 minute every Tonga, and filter and remove residue adds Moschus in this wine liquid more in proportion, the mixing bottling, and sealing and standing can be standby about ten days.

When the combination compound recipe was made powder, its method was that various components are ground into powder (crossing the above sieve of 100 orders), is mixed into powder then, according to the clinical application effective dose, can directly draw away mixing in water for oral taking with yellow wine, and said preparation can be for not alcoholic patient use.

When the combination compound recipe is made pill-type, its method be with the plant medicine material of combination in the compound recipe through immersion fry in shallow oil juice be condensed into dry extract in dry powder (crossing the sieves more than 100 orders), again with remaining animal fat pulverizing medicinal materials powdered (crossing 100 orders) with top sieve, again with the two mix homogeneously, with Chinese liquor, rice vinegar half and half, medicine juice is an excipient, make the ball shape, in order to taking, the said preparation volume is little, active ingredient height (suitable crude drug in whole 3 grams of the every gram of concentrated dry powder), it is lasting to absorb the slow efficacy of a drug, be applicable to the chronic disease use, take easily, easy to carry.

When the making capsule was for oral administration in the combination compound recipe, its method was that the mixing concentrate drying powder of pill agent is made capsule with machinery.

Combination compound recipe every dose of medicine is a course of treatment, takes medicine each course of treatment 20 days, and general patient has three courses of treatment can produce effects and healing.Divide early, middle and late three one after each meals every day.Medicated wine is directly drunk, and pill, medicamental pulverata powder, available yellow wine are done to draw to take.

The application's combination compound recipe has the effect of flat invigorating the liver and kidney, adjusting negative and positive and blood blood stasis dispelling, dispelling wind and removing obstruction in the collateral, reducing swelling and alleviating pain, strong muscles and bones, the circulation of the body of promotion inner blood is arranged, increase the heart and brain flow, reduce and reduce oxygen consumption, strengthen metabolism and human body resistivity, suppress and prevent the effect of hyperosteogeny pathological changes expansion, and reach the healing purpose.

The application's combination compound recipe cures mainly cervical vertebra, lumbar vertebra, thoracic vertebra and bones of limbs hyperosteogeny.Quadriplegia and anti-other hamartoplasia (as cyclomastopathy) of anti-cancerous protuberance that Fengshi Guanjie pain, soft tissue injury, control brain cardiovascular disease are caused also have significant curative effect.

Claims

1, a kind of Chinese medicine for oral administration for the treatment of bone disease, it is medicated wine, powder, pill and the capsule of being made by following raw materials by weight percent:

Sanguis Draxonis 7.75-11.63%,

Olibanum (processed) 7.04-10.50%,

Myrrha (processed) 7.04-10.50%,

Fructus Lycii 4.65-6.98%,

Typhonium flagelliforme (Lodd.) Blume 9.74-14.54%,

System Zaocys 3.88-5.82%,

Moschus 0.12-0.17%,

System Squama Manis 5.82-8.73%,

Roasted RADIX PUERARIAE 5.82-8.73%,

Radix Clematidis 5.82-8.73%,

Cattle sunset 3.88-5.82%,

Radix Paeoniae Alba (parched) 5.82-8.73%,

Scorpio 1.94-2.91%,

Scolopendra 1.94-2.91%,

Flos Carthami 1.94-2.91%,

System vomiting nut 0.39-0.58%,

Pyritum (processed) 0.78-1.16%,

System Os Tigris 1.16-1.75%,

System river 2.33-3.49%,

Eupolyphaga Seu Steleophaga 2.33-3.49%.

2, Chinese medicine according to claim 1, wherein:

Sanguis Draxonis 16-24g,

Olibanum (processed) 14.4-21.6g,

Myrrha (processed) 14.4-21.6g,

Fructus Lycii 9.6-14.4g,

Typhonium flagelliforme (Lodd.) Blume 20-30g,

System Zaocys 8-12g,

Moschus 0.24-0.36g,

System Squama Manis 12-18g,

Roasted RADIX PUERARIAE 12-18g,

Radix Clematidis 12-18g,

Cattle sunset 8-12g,

Radix Paeoniae Alba (parched) 12-18g,

Scorpio 4-6g,

Scolopendra 4-6g,

Flos Carthami 4-6g,

System vomiting nut 0.8-1.2g,

Pyritum (processed) 1.6-2.4g,

System Os Tigris 2.4-3.6g,

Radix Aconiti Preparata 4.8-7.2g,

Eupolyphaga Seu Steleophaga 4.8-7.2g.

3, Chinese medicine according to claim 2, wherein: Sanguis Draxonis 20g, Olibanum (processed) 18g, Myrrha (processed) 18g, Fructus Lycii 12g, Typhonium flagelliforme (Lodd.) Blume 25g, system Zaocys 10g, Moschus 0.3g, system Squama Manis 15g, roasted RADIX PUERARIAE 15g, Radix Clematidis 15g, cattle sunset 10g, Radix Paeoniae Alba (parched) 15g, Scorpio 5g, Scolopendra 5g, Flos Carthami 5g, system vomiting nut 1g, Pyritum (processed) 2g, system Os Tigris 3g, Radix Aconiti Preparata 6g, Eupolyphaga Seu Steleophaga 6g.

4, Chinese medicine according to claim 1, it is characterized in that medicated wine is wherein made by following method: the Chinese medicine of all the other except that Moschus mixed powder in the Chinese medicine is broken into coarser powder, and the Chinese liquor of spending with 45 degree-60 is solvent, the medicated wine ratio is 1: 5-10, medicated wine mixing room temperature lower seal infuse is about ten days, and heat decocts boiling 15-30 minute, filter and remove residue every Tonga, in proportion Moschus is added in the wine liquid, sealing and standing got final product about ten days again.

5, Chinese medicine according to claim 1 is characterized in that powder is wherein made by following method: the various components in the Chinese medicine are ground into powder cross sieve more than 100 orders, be mixed into powder then.

6, Chinese medicine according to claim 1, it is characterized in that pill is wherein made by following method: the plant medicine material in the Chinese medicine is fried in shallow oil the dried powder that juice is condensed into dry extract through immersion cross 100 orders with top sieve, again remaining animal fat pulverizing medicinal materials powdered is crossed the sieve more than 100 orders, with the two mix homogeneously, with Chinese liquor, rice vinegar half and half, add excipient, make the ball shape.