CN108947984B - 一种普仑司特的制备方法 - Google Patents
一种普仑司特的制备方法 Download PDFInfo
- Publication number
- CN108947984B CN108947984B CN201811082398.2A CN201811082398A CN108947984B CN 108947984 B CN108947984 B CN 108947984B CN 201811082398 A CN201811082398 A CN 201811082398A CN 108947984 B CN108947984 B CN 108947984B
- Authority
- CN
- China
- Prior art keywords
- solvent
- reaction
- pranlukast
- mixture
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
波数(cm<sup>-1</sup>) | 震动类型 |
1252.79 | V<sub>C-O-C</sub> |
1646.27 | V<sub>C=O</sub> |
1662.67 | V<sub>C=O</sub> |
2941.49 | V<sub>C-H</sub> |
3096.77 | V<sub>Ar-H</sub> |
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811082398.2A CN108947984B (zh) | 2018-09-17 | 2018-09-17 | 一种普仑司特的制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811082398.2A CN108947984B (zh) | 2018-09-17 | 2018-09-17 | 一种普仑司特的制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN108947984A CN108947984A (zh) | 2018-12-07 |
CN108947984B true CN108947984B (zh) | 2020-07-07 |
Family
ID=64476640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201811082398.2A Active CN108947984B (zh) | 2018-09-17 | 2018-09-17 | 一种普仑司特的制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108947984B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112679374A (zh) * | 2021-01-12 | 2021-04-20 | 湖南复瑞生物医药技术有限责任公司 | 2-氟-6-(三氟甲基)苯甲酰胺的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9224922D0 (en) * | 1992-11-27 | 1993-01-13 | Smithkline Beecham Plc | Process |
CN104761524A (zh) * | 2014-01-07 | 2015-07-08 | 清华大学 | 一种化合物及其在制备抗寄生虫病药物中的应用 |
CN104387268A (zh) * | 2014-11-07 | 2015-03-04 | 济南大学 | 一种合成普仑司特中间体对苯丁氧基苯甲酸的新工艺 |
CN106588897A (zh) * | 2017-02-28 | 2017-04-26 | 上海微巨实业有限公司 | 一种普仑司特的新制备方法 |
-
2018
- 2018-09-17 CN CN201811082398.2A patent/CN108947984B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN108947984A (zh) | 2018-12-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR102075371B1 (ko) | 퀴놀린 유도체 제조 방법 | |
JPH0371431B2 (zh) | ||
WO1998050346A2 (en) | Acetamide and urea derivatives, process for their preparation and their use in the treatment of cns disorders | |
TWI580675B (zh) | Preparation of 4- [5- (pyridin-4-yl) -1H-1,2,4-triazol-3-yl] pyridine-2-carbonitrile and intermediates | |
CN105418483A (zh) | 一种结晶型乙磺酸尼达尼布的制备方法 | |
CN111763170B (zh) | 氟马替尼中间体的制备方法 | |
JP4389205B2 (ja) | 4−アミノキナゾリン化合物の製法 | |
CN108947984B (zh) | 一种普仑司特的制备方法 | |
CN101372475B (zh) | 芳杂环取代的二苯脲类衍生物及其用途 | |
CN107311893B (zh) | 热敏增感剂n-对甲苯磺酰-n’-(3-对甲苯磺酰氧基苯基)脲的合成方法 | |
CN112979544A (zh) | 一种卡博替尼或其盐的制备方法 | |
CN105085595B (zh) | 一种脱酰基保护合成2,6‑位卤代嘌呤核苷的方法 | |
CN109836381A (zh) | 多受体酪氨酸激酶抑制剂及其中间体的制备方法 | |
CN107698501A (zh) | 5,6‑二甲基‑2‑羟基烟酸的制备工艺 | |
JPH0374671B2 (zh) | ||
CN109810052B (zh) | 一种高选择性的阿帕替尼的简便制备方法 | |
CN105503859A (zh) | 阿哌沙班的纯化方法 | |
CN107573263B (zh) | 一种ω-取代缩二脲类化合物的合成方法 | |
WO2016034150A1 (zh) | 博舒替尼及其结晶的制备方法 | |
CN109970654B (zh) | 一系列取代2-苯基吡唑衍生物及其制备方法和应用 | |
CN105250228B (zh) | 一种吉非替尼的片剂及其原料的制备方法 | |
RU2614979C1 (ru) | Способ получения 4-[2-R-2-оксоэтил]-5-нитробензол-1,2-дикарбоновых кислот | |
CN114685365A (zh) | 一种吡氟酰草胺的合成方法 | |
CN105859612A (zh) | 一种索拉菲尼的制备方法 | |
CN103819315A (zh) | 一种白藜芦醇三甲醚的新晶型及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of pranlast Effective date of registration: 20210423 Granted publication date: 20200707 Pledgee: Yantai rural commercial bank Limited by Share Ltd. Development Zone sub branch Pledgor: YANTAI VALIANT PHARMACEUTICAL Co.,Ltd. Registration number: Y2021980002916 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20220523 Granted publication date: 20200707 Pledgee: Yantai rural commercial bank Limited by Share Ltd. Development Zone sub branch Pledgor: YANTAI VALIANT PHARMACEUTICAL CO.,LTD. Registration number: Y2021980002916 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right |