CN108936654A - A kind of health food of strengthen immunity and its application - Google Patents
A kind of health food of strengthen immunity and its application Download PDFInfo
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Classifications
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
- A23L29/35—Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Botany (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Immunology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of health food of strengthen immunity and its applications.The health food is made of the raw material of following parts by weight: rhizoma polygonati 470 ~ 520, the fruit of glossy privet 470 ~ 520, fingered citron 470 ~ 520, Rhizoma Gastrodiae 310 ~ 350,5 ~ 15 parts of steviol glycoside, 510 ~ 530 parts of dextrin.The theoretical and clinical experience choosing side that the present invention is raised according to the dietary therapy of Chinese medicine, selected raw material is that Pharmacopoeia of the People's Republic of China version in 2010 is recorded.Experiments have shown that health food of the invention belongs to nontoxic grade by acute toxicity classification, the antibody-producting cell proliferation that can promote the delayed allergy of mouse, promote mouse, the serum hemolysin of mouse is improved, and the weight of mouse, internal organs/weight ratio and NK cell activity are all had no significant effect.Therefore, health food of the invention is with a wide range of applications in terms of enhancing human immunity.
Description
Technical field
The invention belongs to the technical fields of health food, and in particular to a kind of health food of strengthen immunity and its answer
With.
Background technique
A kind of immune aversion response for referring to living organism identification and excluding antigenic substance.Human body itself has inborn
Physiological immune function, basic meaning are the injuries for protecting human body not by " allosome ".Immunity is the defence of human body itself
Mechanism, is human bioequivalence and the foreign matter (virus, bacterium etc.) for eliminating external intrusion, processing aging, damage, death, denaturation oneself
Body cell, and the ability of identification and processing vivo mutations cell, virus infected cell.A variety of causes prevent immune system from
In the case where normal performance protective effect, body easily incurs the infection such as bacterium, virus, fungi, therefore hypoimmunity is most straight
The performance connect is exactly liable to illness.Only immune system plays under normal operation acts on and keeps opposite balance accordingly,
Body can just survive.
With economic continuous development, the work and study pressure of the continuous quickening of rhythm of life, people is also gradually increased.Such as
Fruit body is chronically at this state, immunity of organisms can be made to decline, and eventually leads to the sub-health state of body.Therefore, in order to
Prevention disease improves the quality of living, promotes longevity, and developing high-quality and efficient health food to improve body immunity seems outstanding
It is important.In order to reach health skills, other than notably daily life habit adjustment, the adjustment of diet also can reach health mesh
, adventure in daily life of the China over thousand experienced Shennong's Herbal, " dietetic materia medica ", Compendium of Material Medica etc., by food
And medical melt into one, develop the culture of " integration of drinking and medicinal herbs " out, the comprehensive function of existing drug and food, but be able to satisfy nutrition with
The demand of health care, healthcare function are to adjust human physiological functions almost without side-effects to body under the premise of.
Rhizoma polygonati is liliaceous plant polygonatum kingianurn (Polygonatum Kingianum Coll.et Hemsl), rhizoma polygonati
(Polygonatum sibiricum Red) or the dry rhizome of polygonatum cyrtonema (Polygonatum cyrtonema Hua).It is yellow
Essence has the effect of boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney-nourishing.For spleen deficiency, fatigue and asthenia, deficiency of stomach-Yin, dry deficiency of food, the deficiency syndrome of the lung
Cough caused by dryness, overstrain cough hemoptysis, asthenia of essence and blood, soreness and weakness of waist and knees, poliosis, Heat Diabetes.Resist modern pharmacological studies have shown that rhizoma polygonati has
Aging, hypoglycemic, reducing blood lipid, raising and improvement are remembered, are antitumor, adjusting the effects of immune, antiviral, anti-inflammatory.Rhizoma polygonati is to defend
The approval of life portion is both food and the article of drug, can be used as the raw material of health food.
The fruit of glossy privet is the ripening fruits of Oleaceae glossy privet platymiscium glossy privet (Ligustrym lucidum Ait).The fruit of glossy privet
With tonifying the liver and kidney, the effect of UFA eyesight, mental-tranquilization.Modern pharmacological studies have shown that the fruit of glossy privet have antitumor, protect liver,
The effects of adjusting immune function, anti-aging, anti-inflammatory, reducing blood lipid.The fruit of glossy privet is that Ministry of Public Health's approval is both food and drug
Article can be used as the raw material of health food.
Fingered citron is the dry of rutaceae fingered citron (Citrus medica L.var Sarcodactylis Swingle)
Dry fruit.Fingered citron has dispersing stagnated hepatoqi, protecting the stomach and relieve the pain, eliminating dampness and eliminating phlegm effect.Modern pharmacological studies have shown that fingered citron has drop blood
Pressure, eliminating the phlegm of relievining asthma, adjusts the effects of immune function at anti-inflammatory, antiallergy, spasmolysis.Fingered citron be the Ministry of Public Health approval be both food and
The article of drug can be used as the raw material of health food.
Rhizoma Gastrodiae is the dry rhizome of orchid Rhizoma Gastrodiae (Gastrodia elate Blume).With it is calming the liver to stop the wind, dispel
The effect of wind and removing obstruction in channels.Modern pharmacological studies have shown that Rhizoma Gastrodiae have blood pressure lowering, analgesia, calmness, anticonvulsion, improving eyesight increase intelligence, it is anti-inflammatory,
The effects of adjusting immune function.Rhizoma Gastrodiae is that Ministry of Public Health's approval is both food and the article of drug, can be used as the original of health food
Material.
Depending on the selection gist dosage form of auxiliary material.According to " health food registration management method (tentative) " the 63rd article of rule
Determine, selected auxiliary material dextrin, steviol glycoside can be used as the auxiliary material of health food.
Modern separation technology promote active ingredient of natural product extract separation with application development, but extract it is effective at
It point must its clear physicochemical property, discrimination method and through stringent toxicological assessment.Currently, Corporation R & D health food is more
Using outsourcing natural extracts as raw material.It is difficult to ask for product physicochemical property, extraction process and safety to supplier
Evaluation data, if avoid generating harmful intermediate or residue, lack experimental data more." health food Management Office
Method ", " health food registration management method " clearly stipulate that raw material and auxiliary material used in health food should be to human healths
It is safe and harmless, since health food adjusts body function often using can just show for a period of time, so, it is ensured that it is eaten for health care
The safety of product raw material, validity, controllability, it is particularly important.
The present invention is using conventional extractive technique, with Thick many candies for significant ingredient, from raw material to finished product, according to safety
It is required that monitor, set up successive check layer by layer, product yield height and strengthen immunity significant effect.So far, have no other documents and
Patent disclosure report prepares the health food enhanced human immunity using the prescription.
Summary of the invention
The object of the present invention is to provide it is a kind of can effectively enhance immunity of organisms, safely and effectively and have no toxic side effect
Health food.
The present invention adopts the following technical scheme:
A kind of health food of strengthen immunity provided by the invention, is made of the raw material of following parts by weight: rhizoma polygonati 470 ~ 520
Part, 470 ~ 520 parts of the fruit of glossy privet, 470 ~ 520 parts of fingered citron, 310 ~ 350 parts of Rhizoma Gastrodiae, 5 ~ 15 parts of steviol glycoside, 510 ~ 530 parts of dextrin.
The health food is made of the raw material of following parts by weight: 490 ~ 505 parts of rhizoma polygonati, 490 ~ 505 parts of the fruit of glossy privet, fingered citron
490 ~ 505 parts, 325 ~ 340 parts of Rhizoma Gastrodiae, 7 ~ 9 parts of steviol glycoside, 515 ~ 525 parts of dextrin.
Preferably, the health food is made of each raw material of following parts by weight: 500 parts of rhizoma polygonati, 500 parts of the fruit of glossy privet, Buddhist
500 parts of hand, 333 parts of Rhizoma Gastrodiae, 8 parts of steviol glycoside, 520 parts of dextrin.
Health food of the present invention the preparation method is as follows: weigh rhizoma polygonati, the fruit of glossy privet, fingered citron, Rhizoma Gastrodiae by formula rate, add water
It decocts twice, each 1h, adds 7 times of amount water for the first time, second plus 6 times of amount water, extracting solution filtering, 60 ~ 80 DEG C are concentrated under reduced pressure into
Relative density is 1.26 ~ 1.32, obtains clear cream；It is added in clear cream and presses the weighed dextrin of formula rate, mixing, 60 ~ 80 DEG C of dryings, powder
It is broken, 80 meshes are crossed, get dry extract powder；70% ethanol solution containing steviol glycoside is first added in dried cream powder, adds appropriate 70% ethyl alcohol
Solution softwood, 14 meshes granulation, obtains wet granular；65 ~ 75 DEG C of dryings of wet granular, obtain dry particl.
Further, the invention also provides by the above prescription proportion granule obtained for enhancing human immunity
Application in health food of the preparation for strengthen immunity.
1 safety toxicology tests (rat acute toxicity test)
1.1 experimental animals: KM mouse 20 (half male and half female) of Sichuan Provincial Academy of Traditional Chinese Medicine Experimental Animal Center offer, body
Weigh 18 ~ 22g, SD rat 20 (half male and half female), 182 ~ 214g of weight, quality certification number: the river SCXK() 2013-19.SPF grades.
The selection of 1.2 dosage gives mode with tested material: setting mono- dosage group of 15000mg/kg.BW, passes through by 20mL/kg.BW
Mouth stomach-filling.Animal fasting 16h before stomach-filling, unlimited drinking-water are observed 7 days after contaminating for the first time.
1.3 test methods: according to Ministry of Health of the People's Republic of China " health food is examined and assessment technique specification "
(2013 editions), safety toxicology test in acute oral toxicity test prescriptive procedure carry out.
1.4 experiment statistics and result:
Health food granule of the present invention is to large and small mouse acute oral toxicity test as a result, being shown in Table 1.
The health food granule of the present invention of table 1 to large and small mouse acute oral toxicity test result (±S)
By 1 result of table as it can be seen that being observed 7 days respectively with the large and small mouse of the dosage stomach-filling of 15000 mg/kg.BW, two kinds of genders, big,
The general appearance and behavior of mouse are showed no exception, have no animal dead in the observation period, and when off-test puts to death animal, substantially solve
Cut open naked eyes no abnormality seen.Health food granule of the present invention is all larger than 15000mg/kg.BW to large and small mouse acute oral MTD value,
Belong to nontoxic grade by acute toxicity classification.
2 strengthen immunity zooperies
2.1 experimental animals: KM mouse 160 (female) of Sichuan Provincial Academy of Traditional Chinese Medicine Experimental Animal Center offer, weight 18
~ 22g, quality certification number: the river SCXK() 2013-19.SPF grades.
The selection of 2.2 dosage gives mode with animal subject: setting 1000mg/kg.BW, 2000mg/kg.BW, 3000mg/
Tri- dosage groups of kg.BW (10 times, 20 times, 30 times that are respectively equivalent to human body recommended intake), weigh respectively 12.5g,
(yellowish-brown coloured particles, specification are 3g/ bags to 25.0g, 37.5g tested material, and adult recommended intake is 2 bags/day, i.e. 6000mg/
60kgBW) plus distilled water is mixed to 250mL, is finished and is matched again, separately sets distilled water negative control group, every group of 40 animals.Respectively
One group, two groups, three groups, four groups are immunized, wherein one group is tested for Turnover of Mouse Peritoneal Macrophages phagocytosis chicken red blood cells；Two groups of use
It is tested in NK cytoactive detection and lymphocyte transformation；Three groups for antibody-producting cell experiment, serum hemolysin measurement and
Delayed allergy test；Four groups are tested for mouse carbonic clearance.Mouse presses the once oral stomach-filling of 20mL/kg.BW weight, even
It is continuous to give 30 days, claim a weight weekly, adjusts stomach-filling volume.
2.3 test methods: according to Ministry of Health of the People's Republic of China " health food is examined and assessment technique specification "
(2013 editions), weight, internal organs/weight ratio measurement in strengthen immunity zoopery, delayed allergy, ConA induction
Mouse lymphocyte conversion test, antibody-producting cell detection, serum hemolysin measurement, mouse carbonic clearance test, mouse abdomen
Chamber macrophage swallows chicken red blood cell test, and the prescriptive procedure of NK cell activity assays carries out.
2.4 experiment statistics and result:
2.4.1 influence of the health food granule of the present invention to mouse weight
2 each group mouse of table original body mass (±S)
3 each group mouse of table mid-term weight (±S)
4 each group mouse of table end weight (±S)
Influence that the health food granule of the present invention of table 5 increases weight to mouse weight (±S)
By table 2-5 result as it can be seen that one group, original body mass and feminine gender two groups immune, that three groups and immune four groups of animals is immunized is immunized
Control group is compared, and through homogeneity test of variance, variance is neat (P > 0.05), and the results of analysis of variance (P > 0.05), illustrates that each group is dynamic
Original body mass between object and negative control group is balanced.One, two, three, four group of each dosage group animal experiment mid-term, end is immunized
The growth of mouse weight is compared with negative control group compared with there are no significant difference (P > 0.05) during the weight and test of phase.
2.4.2 health food granule of the present invention is shown in Table 6 to the influence of mice organs/weight ratio.
The health food granule of the present invention of table 6 to the influence of mice organs/weight ratio (±S)
By 6 result of table as it can be seen that after continuous gavage 30 days, spleen/weight ratio, the thymus gland/weight ratio of three dosage group animals
Compared with negative control group, it is statistically analyzed, difference that there are no significant (P > 0.05).
2.4.3 influence of the health food granule of the present invention to mouse cell immune function
2.4.3.1 influence of the health food granule of the present invention to mouse delayed allergy, is shown in Table 7.
The health food granule of the present invention of table 7 to mouse delayed allergy influence (±S)
By 7 result of table as it can be seen that after continuous gavage 30 days, the pedal swelling of three dosage group animals compared with negative control group, is passed through
Statistical procedures have significant difference (P < 0.01, P < 0.05, P < 0.05).
2.4.3.2 influence of the health food granule of the present invention to the ConA mouse lymphocyte conversion test induced, is shown in
Table 8.
The health food granule of the present invention of table 8 to the ConA mouse lymphocyte conversion test induced influence (±S)
By 8 result of table as it can be seen that after continuous gavage 30 days, the lymphopoiesis ability and negative control group of three dosage group animals
It compares, is statistically analyzed, there was no significant difference (P > 0.05).
Health food granule health food granule of the present invention of the present invention is positive to mouse cell immunity test result.
2.4.4 influence of the health food granule of the present invention to mouse humoral immune
2.4.4.1 influence of the health food granule of the present invention to mouse antibodies cellulation, is shown in Table 9.
The health food granule of the present invention of table 9 to mouse antibodies cellulation influence (±S)
By 9 result of table as it can be seen that after continuous gavage 30 days, the hemolysis plaque number of three dosage group animals compared with negative control group,
It is statistically analyzed, high dose group has significant difference (P < 0.01).
2.4.4.2 influence of the health food granule of the present invention to mice serum hemolysin, is shown in Table 10.
The health food granule of the present invention of table 10 to mice serum hemolysin influence (±S)
By 10 result of table as it can be seen that after continuous gavage 30 days, the antibody product of three dosage group animals compared with negative control group, is passed through
Statistical procedures, middle and high dosage group have significant difference (P < 0.01, P < 0.01).
Health food granule of the present invention is positive to mouse humoral immune test result.
2.4.5 health food granule of the present invention is to the influence of mouse monokaryon-macrophage phagocytic function
2.4.5.1 health food granule of the present invention is shown in Table 11 to the influence of mouse monokaryon-macrophage carbonic clearance function.
The health food granule of the present invention of table 11 to the influence of mouse monokaryon-macrophage carbonic clearance function (±S)
By 11 result of table as it can be seen that after continuous gavage 30 days, the carbonic clearance ability of three dosage group animals compared with negative control group,
It is statistically analyzed, there was no significant difference (P > 0.05).
2.4.5.2 influence of the health food granule of the present invention to mouse macrophage phagocytosis chicken red blood cell ability, is shown in Table
12。
The health food granule of the present invention of table 12 to mouse macrophage phagocytosis chicken red blood cell ability influence (±S)
By 12 result of table as it can be seen that after continuous gavage 30 days, the phagocytic rate and phagocytic index and negative control of three dosage group animals
Group is compared, and is statistically analyzed, and there was no significant difference (P > 0.05).
Health food granule of the present invention is negative to mouse monokaryon-macrophage phagocytic function test result.
2.4.6 health food granule of the present invention is shown in Table 13 to the active influence of NK cells in mice.
The influence active on NK cells in mice of the health food granule of the present invention of table 13 (±S)
By 13 result of table as it can be seen that after continuous gavage 30 days, the NK cell activity of three dosage group animals compared with negative control group,
It is statistically analyzed, there was no significant difference (P > 0.05).
Test result shows: health food granule of the present invention is continuously equivalent to 1000,2000,3000mg/kg.BW(
10 times, 20 times, 30 times of human body recommended intake) weight, internal organs/weight ratio of the dosage stomach-filling mouse after 30 days, to mouse
It has no significant effect；It is negative to the monocytes/macrophages phagocytic function test result of mouse；To the NK cell activity assays knot of mouse
Fruit is negative；It is positive to the test for celluar immunity result of mouse, it is positive to the test for humoral immunity result of mouse.According to " health care food
Product examine is tested and assessment technique specification " (2013 editions) can be determined that, health food of the present invention has the function of strengthen immunity to animal
Energy.
Compared with prior art, the present invention has the advantage that each raw material that 1) present invention uses more than extensive research
On the basis of the effect of strengthen immunity, a large amount of combination is attempted, and synergistic effect is observed in the above ratio range,
And significant effect；2) raw material that the present invention selects is medicinal material, is suitable for being prepared into granule after water extracts: dispersing fast, mouthfeel
Good, product is conducive to storage, easy to carry, is suitable for industrialized production；3) Chinese medicine of present invention selection integration of drinking and medicinal herbs, with reference to the modern times
Pharmacological research achievement is formed according to theory of traditional Chinese medical science scientific composition, according to security requirement, determines the weight of each raw material, and through dynamic
Object experiments have shown that, the invention belongs to nontoxic grade health foods, and have the function of enhance immunity of organisms.
Specific embodiment
In order to make those skilled in the art more fully understand technical solution of the present invention, below by specific embodiment pair
The present invention is described in further detail.Obviously, described embodiments are only a part of the embodiments of the present invention, rather than complete
The embodiment in portion.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, shall fall within the protection scope of the present invention.
Embodiment 1: the health food enhanced human immunity is prepared
It matches (parts by weight): rhizoma polygonati 500, the fruit of glossy privet 500, fingered citron 500, Rhizoma Gastrodiae 333, dextrin 520, steviol glycoside 8.
Preparation method: weighing rhizoma polygonati, the fruit of glossy privet, fingered citron, Rhizoma Gastrodiae by formula rate, add water to cook twice, each 1h, and first
Secondary plus 7 times of amount water, second plus 6 times of amount water, extracting solution filtering, it is 1.26 ~ 1.32 that 60 ~ 80 DEG C, which are concentrated under reduced pressure into relative density,
Obtain clear cream；It is added in clear cream and presses the weighed dextrin of formula rate, mixing, 60 ~ 80 DEG C dry, pulverize, and cross 80 meshes, get dry extract
Powder；70% ethanol solution containing steviol glycoside is first added in dried cream powder, adds appropriate 70% ethanol solution softwood, 14 mesh Shai Zhi
Grain, obtains wet granular；65 ~ 75 DEG C of dryings of wet granular, obtain dry particl, and yield 94.25%, after measured, every 100g contain Thick many candies
1.4g。
Embodiment 2: the health food enhanced human immunity is prepared
It matches (parts by weight): rhizoma polygonati 470, the fruit of glossy privet 500, fingered citron 470, Rhizoma Gastrodiae 350, dextrin 530, steviol glycoside 5.
Preparation method: with embodiment 1.
Embodiment 3: the health food enhanced human immunity is prepared
It matches (parts by weight): rhizoma polygonati 500, the fruit of glossy privet 505, fingered citron 505, Rhizoma Gastrodiae 340, dextrin 510, steviol glycoside 10.
Preparation method: with embodiment 1.
Embodiment 4: the health food enhanced human immunity is prepared
It matches (parts by weight): rhizoma polygonati 520, the fruit of glossy privet 520, fingered citron 520, Rhizoma Gastrodiae 325, dextrin 530, steviol glycoside 15.
Preparation method: with embodiment 1.
Embodiment 5: the health food enhanced human immunity is prepared
It matches (parts by weight): rhizoma polygonati 500, the fruit of glossy privet 490, fingered citron 500, Rhizoma Gastrodiae 310, dextrin 520, steviol glycoside 8.
Preparation method: with embodiment 1.
Claims (5)
1. a kind of health food of strengthen immunity, which is characterized in that be made of the raw material of following parts by weight: rhizoma polygonati 470 ~ 520
Part, 470 ~ 520 parts of the fruit of glossy privet, 470 ~ 520 parts of fingered citron, 310 ~ 350 parts of Rhizoma Gastrodiae, 5 ~ 15 parts of steviol glycoside, 510 ~ 530 parts of dextrin.
2. a kind of health food of strengthen immunity according to claim 1, which is characterized in that the health food by with
The raw materials of lower parts by weight forms: 490 ~ 505 parts of rhizoma polygonati, 490 ~ 505 parts of the fruit of glossy privet, 490 ~ 505 parts of fingered citron, 325 ~ 340 parts of Rhizoma Gastrodiae,
7 ~ 9 parts of steviol glycoside, 515 ~ 525 parts of dextrin.
3. a kind of health food of strengthen immunity according to claim 1 or 2, which is characterized in that the health food
It is made of each raw material of following parts by weight: 500 parts of rhizoma polygonati, 500 parts of the fruit of glossy privet, 500 parts of fingered citron, 333 parts of Rhizoma Gastrodiae, steviol glycoside 8
Part, 520 parts of dextrin.
4. a kind of health food of strengthen immunity according to claim 1 or 2, which is characterized in that the health food
The preparation method is as follows: weigh rhizoma polygonati, the fruit of glossy privet, fingered citron, Rhizoma Gastrodiae by formula rate, add water to cook twice, each 1h, for the first time
Add 7 times of amount water, second plus 6 times of amount water, extracting solution filtering, it is 1.26 ~ 1.32 that 60 ~ 80 DEG C, which are concentrated under reduced pressure into relative density, is obtained
Clear cream；It is added in clear cream and presses the weighed dextrin of formula rate, mixing, 60 ~ 80 DEG C dry, pulverize, and cross 80 meshes, get dry extract powder；
70% ethanol solution containing steviol glycoside is first added in dried cream powder, adds appropriate 70% ethanol solution softwood, 14 meshes are pelletized,
Obtain wet granular；65 ~ 75 DEG C of dryings of wet granular, obtain dry particl.
5. a kind of health food of strengthen immunity described in any one of -4 is immune for enhancing in preparation according to claim 1
Application in the health food of power.
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