CN102631494A - Traditional Chinese medicine composition capable of improving immunity and resisting fatigue - Google Patents

Traditional Chinese medicine composition capable of improving immunity and resisting fatigue Download PDF

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CN102631494A
CN102631494A CN2012101220315A CN201210122031A CN102631494A CN 102631494 A CN102631494 A CN 102631494A CN 2012101220315 A CN2012101220315 A CN 2012101220315A CN 201210122031 A CN201210122031 A CN 201210122031A CN 102631494 A CN102631494 A CN 102631494A
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cordyceps
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radix ginseng
stigma croci
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CN102631494B (en
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杨翠红
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Dafeng District Productivity Promotion Center Yancheng City
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Abstract

The invention relates to a health care product composition capable of improving human body immunity and resisting fatigue. The composition comprises the following active ingredients: ginseng, crocus sativus and cordyceps sinensis. The composition has the functions of enhancing organism immunity, resisting fatigue, calming the nerves, resisting viruses and building bodies, and has obvious curative effects and mild effects.

Description

A kind of raising immunity, antifatigue Chinese medicine composition
Technical field
The present invention relates to a kind of collaborative Chinese medicine composition that improves body immunity, resisting fatigue and enriching yin and nourishing kidney that has.
Technical background
Along with socioeconomic continuous development; The raising day by day of people's living standard; People increase the degree of keeping a grip on of health gradually; Live in now all be that we receive many outside threats easily at everyone health, comprise air pollution, video pollution, environmental pollution, operating pressure, economic pressures, bacterial virus, improper diet or the like.Moreover, because the variation of city work, rhythm of life is easy to make the people to produce confirmed fatigue, i.e. sub-health state, the factor of all these unfavorable health can make us usually that spirit can not be concentrated, hypomnesis, often indolent and listless, old and feeble ahead of time.Therefore improve autoimmunity, the ability that strengthens the various unfavorable health factors of antagonism is most important.
The present health product that are used for enhancing human body immunity power on the market are of a great variety, but action effect is uneven.
Summary of the invention
The technical problem that the present invention will solve is: the Chinese medicine composition that the purpose of this invention is to provide a kind of enhancing human body immunity power, resisting fatigue and enriching yin and nourishing kidney.Through being main Chinese crude drug with Radix Ginseng, Stigma Croci and Cordyceps, through mutual synergistic function, in the hope of disease resistance enhancemen, enhance immunity effect, the engineering of alleviating physical fatigue and kidney invigorating and YANG supporting.
For solving the problems of the technologies described above; The present invention provides a kind of collaborative body immunity, antifatigue Halth-care composition of improving that have; It is characterized in that described compositions comprises that active component is a kind of to have Synergistic and improve human body immunity of organisms, resisting fatigue and have the Chinese medicine health care product compositions of kidney invigorating and YANG supporting, is characterized in that described compositions comprises Radix Ginseng, Stigma Croci and Cordyceps.In the active component by weight: Radix Ginseng is 3-65 part, and Stigma Croci is 2-55 part, Cordyceps 4-60 part.Preferably: Radix Ginseng is 5-50 part, and Stigma Croci is 4-40 part, Cordyceps 5-45 part.
Radix Ginseng: related Radix Ginseng is meant the general name of a kind of herbaceos perennial of the Umbellales Araliaceae Radix Ginseng Panax of family among the present invention, comprises Radix Ginseng Rubra, Radix Ginseng, Radix Panacis Quinquefolii (Radix Panacis Quinquefolii), Radix Glehniae, Radix Codonopsis and Radix Pseudostellariae etc.Radix Ginseng among the present invention comprises through processing refinement back Radix Ginseng extract, the various forms in grinding descendant's pure extract powder or Radix Ginseng growth course.
Stigma Croci: involved in the present invention to Stigma Croci (claiming Stigma Croci, Stigma Croci again), be the perennial flowers of a kind of Liliales Iridaceae crocus.Stigma Croci among the present invention comprises crocein powder after grinding, obtains Stigma Croci extracts or croceous other processing forms through various processes.
Cordyceps: related Cordyceps is meant the fungus (Cordyceps) and the bacterium worm coalition that larva forms of Clavicipitaceae among the present invention under specific condition, comprising: Cordyceps, Cordyceps hawkesii Gary, Cordyceps liangshanensis Zang Hu et Liu, Xinjiang Cordyceps, branch Cordyceps, the leaves of pulse plants restrain Cordyceps, Cordyceps militaris (L.) Link., Wuyi Mountain Cordyceps, dragon's cave-stalactite cave Cordyceps, Zhangjiajie Cordyceps, big cat head Cordyceps, many shells Cordyceps, gentle handle Cordyceps, sagging Cordyceps, Jiangxi Cordyceps, Sichuan Cordyceps, Cordyceps oxycephala, crust grace Cordyceps, Guizhou Cordyceps, Chishui Cordyceps, Dermaptera Cordyceps, intend Bu Banke Cordyceps, Cordyceps martialis Speg., Lou Shan Cordyceps, Mus tail Cordyceps, green nuclear Cordyceps, moorland Cordyceps, luxuriant blue Cordyceps, BUSHICHONGCAO, Cordyceps takaomontana, yellowish Cordyceps militaris (L.) Link., bulb Cordyceps, chafer Cordyceps, Mantidis Cordyceps, froghopper Cordyceps, handle shell Cordyceps, intend luxuriant blue Cordyceps, Cordyceps gracilioides, hair Cordyceps, wireworm Cordyceps, Japanese Cordyceps, Xin Kelai Cordyceps, beak shell Cordyceps, intend dark green Cordyceps, high eyebrow Cordyceps, FENBEICHONGCAO, Dayi Cordyceps, fork-tail Cordyceps, Caulis cyatheae spinulosae Cordyceps, Aeschna melanictera Cordyceps, ant Cordyceps, Luo Baici Cordyceps, Cordyceps kyushuensis, buttress shaft Cordyceps, DAISHICHONGCAO, distortion Cordyceps, rice mountain Cordyceps, two shuttle spore Cordyceps, Cordyceps gunnii (Berk.) Berk. etc.Worm powder after Cordyceps among the present invention comprises Cordyceps and grinds, refine the back Cordyceps extract, or have a form in each growth course of Cordyceps through processing.Cordyceps has the function that tonifying the lung kidney, cough-relieving are coughed, benefit is deficient, support vital essence.According to clinical research, Cordyceps has ten big functions and has foster lung yin, kidney-replenishing, relieving cough and resolving phlegm, anticancer anti-old effect; Be the article of flat nourishing YIN sun, all do not have institute and avoid that (men and women, old and young can both eat, and are the suitable the widest tonics of crowd; And need not avoid certain food, health is had much tonification, mend marrow lung benefiting kidney; And the order property of medicine is gentle, does not attend a meeting like the people that the people is produced is scorching, the benefit of Radix Ginseng is arranged and does not have the evil of Radix Ginseng).Can be used for the pulmonary tuberculosis hemoptysis, diseases such as impotence and seminal emission.
The definition of " collaborative improve " is appreciated that to after several kinds of medical materials combinations among the present invention, the raising of its drug effect during with respect to independent the use; Drug effect is more lasting; Compositions produces beyond thought effect in new control or healthcare field.
In the component of the present invention, Cordyceps is a monarch drug, have building body, regulate immunocompetence, kidney invigorating and YANG supporting, tranquillizing and allaying excitement, etc. medicinal function.Radix Ginseng is a ministerial drug, has strongly invigorating primordial QI, and multiple arteries and veins takes off admittedly, invigorating the spleen to benefit the lung, and promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves, nourishing YIN and invigorating YANG is regulated the effect of immunity.Stigma Croci is an adjuvant, and it is flat to have sweet in the mouth property, dispersing stagnation and relieving accumulation of pathogens, pain relieving, resisting fatigue, the effect of Yin Yang balancing.
The inventor finds that through test compositions of the present invention has outside the remarkable role in synergy, has the effect of enriching yin and nourishing kidney simultaneously on improving body immunity, antifatigue pathology.These single agent are that single agent is incomparable to the action effect of some function of human body after through a certain proportion of compositions.
Compositions of the present invention can directly be pulverized or through the active component of the refining compositions as treatment of the extraction of the conventional extractive technique in this area such as decoction and alcohol sedimentation technique or ethanol extract from water precipitation.Said active component can be processed various pharmaceutical formulations with pharmaceutically acceptable carrier or excipient composition, as is how granular tablet, granule, capsule, or oral liquid etc.According to the use needs, compositions of the present invention also can be processed into slow releasing preparation or quick releasing formulation.Wherein said pharmaceutically acceptable carrier or excipient are selected according to different dosage forms.These used carriers or excipient can determine for the those of ordinary skill of pharmaceutical field.
The method for preparing of oral liquid, can but not only be confined to following a kind of, after active component is mixed; Decoction liquor is filtered in decocte with water, obtains solution; The gained solution concentration is obtained extractum, then gained extractum be dissolved in 5-10 times of weight of extractum weight concentration in the ethanol water according to weight meter 95%, mix; Quantitatively packing obtains oral liquid formulations.
The method for preparing of tablet is that the active component mixture is sieved, and behind the auxiliary agent pulverizing commonly used with preparing tablet, abundant mix homogeneously, crosses the 40-80 eye mesh screen, through tabletting the direct machine of dry powder is pressed into tablet.
The preparation technology of capsule preparations can for, the active component mixture is sieved, pulverizing with preparation tablet auxiliary agent commonly used, fully behind the mix homogeneously, crossing the 40-80 eye mesh screen, through granulating, drying is irritated capsule after the operations such as granulate, polishing, packing gets product.
The invention has the beneficial effects as follows:
Pharmaceutical composition of the present invention has benefiting QI for strengthening the superficies, the effect of human body immunity improving power, and medicine of the present invention is not warm not dry; Effect with invigorating spleen and reinforcing stomach, kidney invigorating and YANG supporting, wet dissipation eliminating impediment, enhancing immunity, resisting fatigue, antiviral, strengthening body; Evident in efficacy, action temperature with, have no side effect.This production of medicine technology is simple, be easy to take, evident in efficacy, be a kind of ideal raising human immunity, antifatigue medicine.
Detailed description of the preferred embodiments
Following examples have been explained various aspects of the present invention.They only in order to explanation, not delimit the scope of the invention.
Embodiment 1: contain the preparation that the people participates in the capsule of Stigma Croci, Cordyceps
Radix Ginseng 65 grams, Stigma Croci 10 grams, Cordyceps 15 grams
Above-mentioned Chinese medicine was soaked 40 minutes, and it is important that the water surface is higher than raw material, adds water inventory and be 8 times of total dose, the little fire in back that the boils attitude of boiling; Keep liquid level and be higher than raw material Chinese medicine height, decocted 2 hours, cross leaching filtrating, add 6 times water of total dose again; The back little fire attitude of boiling of boiling is kept liquid level and is higher than raw material Chinese medicine height, decocts 2 hours, filters twice filtrating of merging; Through concentrating under reduced pressure (pressure 0.06MPa, 65 ℃ of temperature) to dried cream, pulverize; Through 300 mesh sieves, add the magnesium stearate of gross weight 2%, incapsulate and get final product.
Embodiment 2: contain the preparation that the people participates in the tablet of Stigma Croci, Cordyceps
Radix Ginseng 12 grams, Stigma Croci 55 grams, Cordyceps 12 grams
Above-mentioned Chinese crude drug is dried and crushed into coarse powder, with the ethanol of 50-60% be solvent 60-70 ℃ of reflux, extract,, extracting solution is being gone out behind the ethanol, cryoconcentration becomes thick extractum, drying is ground into fine powder, sieves, mixing is granulated, and is pressed into tablet.
Embodiment 3: contain the preparation that the people participates in the capsule of Stigma Croci, Cordyceps
Radix Ginseng 12 grams, Stigma Croci 10 grams, Cordyceps 60 grams
Above-mentioned Chinese crude drug is dried and crushed into fine powder, sieves, mixing is packed into firmly softgel shell, makes Chinese medicine composition of the present invention.
Embodiment 4: contain the preparation that the people participates in the oral liquid of Stigma Croci, Cordyceps
Radix Ginseng 65 grams, Stigma Croci 55 grams, Cordyceps 60 grams
After the said components mixing, decoction liquor is filtered in decocte with water; Obtain solution, the gained solution concentration obtained extractum, then gained extractum be dissolved in 5-10 times of weight of extractum weight concentration in the ethanol water according to weight meter 95%; Mix, quantitatively packing obtains oral liquid formulations.
Embodiment 5: contain the preparation that the people participates in the capsule of Stigma Croci, Cordyceps
Radix Ginseng 3 grams, Stigma Croci 2 grams, Cordyceps 4 grams
Above-mentioned Chinese crude drug is dried and crushed into fine powder, sieves, mixing is packed into firmly softgel shell, makes Chinese medicine composition of the present invention.
Embodiment 6: contain the preparation that the people participates in the capsule of Stigma Croci, Cordyceps
Radix Ginseng is 30 grams, and Stigma Croci is 25 grams, Cordyceps 30 grams
Above-mentioned Chinese crude drug is dried and crushed into fine powder, sieves, mixing is packed into firmly softgel shell, makes Chinese medicine composition of the present invention.
Test example 1: the present invention tests effect of immunologic function
1, the product of testing product: embodiment 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5 is a sample.
2, animal is used in detection: mice, rat, male and female half and half.
3, test basis: Ministry of Public Health " health food check and assessment technique standard " (2003 editions)
4, test item:
4.1 body weight, thymus/body weight ratio, spleen/body weight ratio
4.2comA inductive mouse spleen lymphocyte transformation experiment (mtt assay)
4.3 the tardy paraphilia reaction of the inductive mice of dinitrofluorobenzene (DTH)
4.4 antibody-producting cell detects (Jerne improves slide method)
4.5 serum hemolysin test
4.6 mice carbon clearance test
4.7 Turnover of Mouse Peritoneal Macrophages is engulfed chicken red blood cell experiment (dripping the sheet method)
4.8NK cytoactive is measured
5, testing result and judgement
5.1 the body weight of laboratory animal; Thymus/body weight ratio, the testing result of spleen/body weight ratio shows, under this experimental condition; Institute's full pattern article 500,1000, kg during (be equivalent to respectively be grown up per kg body weight per day recommended intake 5 times, 10 times, 30 times) dosage; Five groups of samples are to the body weight of animal, thymus/body weight ratio, and spleen/body weight ratio is not all seen obvious influence.
5.2comA inductive mouse spleen lymphocyte transformation experiment (mtt assay) is the result show, under this experiment condition, each dose groups optical density difference and solvent control class value relatively all do not have statistical significant difference (P>0.05).The prompting sample does not have the mouse lymphocyte of enhancing multiplication capacity.
5.3 the tardy paraphilia reaction of the inductive mice of dinitrofluorobenzene is (DTH) result show, under this experiment condition, each dose groups optical density difference and solvent control class value compare, and five groups of samples all do not have statistical significant difference (P>0.05).The prompting sample has the tardy paraphilia reagentia of mice that the enhancing dinitrofluorobenzene causes.The test dose group is positive, and the prompting sample can strengthen the mouse cell immunologic function.
5.4 detecting (Jerne improves slide method) result, antibody-producting cell shows; Under this experimental condition; Each dose groups hemolysis plaque number average is higher than the solvent control class value; And low, middle dose groups has statistically-significant difference (P<0.05), and the prompting sample has the ability that mice produces antibody producing cells that strengthens.
5.5 the serum hemolysin result of the test shows that under this experiment condition, each dose groups mice serum half hemolysis value and solvent control class value relatively all do not have statistically-significant difference (P>0.05).The prompting sample does not have the ability that mice produces serum hemolysin that strengthens.The dose groups of a test is positive, and the prompting sample can strengthen the mouse humoral immune function.
5.6 the clearance test of mice carbon is the result show, under this experiment condition, each dose groups mice engulf tree planting A and solvent control class value relatively, all do not have statistical significant difference (P>0.05).Prompting sample five strengthens the effect that carbon is cleaned up ability.
5.7 engulfing chicken red blood cell experiment (dripping the sheet method) result, Turnover of Mouse Peritoneal Macrophages shows; Under this experimental condition; The monokaryon of each sample and each dose groups mice-macrophage phagocytic percentage rate and phagocytic index and solvent control class value relatively all do not have statistical significant difference (P>0.05).Prompting sample five strengthens the effect of Turnover of Mouse Peritoneal Macrophages phagocytic activity.Result of the test is all negative, and the prompting sample does not have enhancing mouse monokaryon-macrophage phagocytic function.
5.8NK measuring the result, cytoactive shows; Under this experimental condition; The NK cytoactive of each dose groups mice all is higher than the solvent control class value, and high dose group has statistical significant difference (P<0.05), the effect that the prompting sample has the NK cytoactive that strengthens mice.
Comprehensive above result of the test, according to health food function of enhancing immunity evaluation criterion, 4 samples of prescription of the present invention all have the function of enhancing immunity.
Test Example 2: the present invention is to improving the clinical efficacy of immune function of human body
The child: immunologic hypofunction, easy catching a cold, average every month more than twice, or suffer from twice above patient of pneumonia in 1 year.
Elderly patients: suffer from multiple chronic disease, be diagnosed as the patient of syndrome of deficiency of lung qi.
2, the method for administration and the course of treatment:
The product of the oral embodiment of the invention 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5 is a sample.Contrast: the single agent capsules of Radix Ginseng, Stigma Croci, Cordyceps, and Radix Ginseng+Stigma Croci capsule (1: 1), Stigma Croci+aweto capsule (1: 1), Radix Ginseng+aweto capsule (1: 1)
Adult: each 3 examples, every day 3 times.
Child below 6 years old: each 1, every day 2-3 time.
Child more than 6 years old: each 2, each 2-3 time.
Above patient was a course of treatment with one month all, and it treats 1-3 the course of treatment.
3, observational technique:
Carry out blood, urine, just routine test and the heart, pulmonary function test, and observe: heating, aversion to cold, sniffle, pharyngeal symptom and whole body situation and the temperature of having a medical check-up, pharyngeal tonsil, the picture of the tongue pulse condition, therapeutic evaluation is carried out in variations such as fingerprint respectively.
4, therapeutic evaluation
Table one prescription of the present invention improves the clinical observation of immune function of human body
Compositions The example number Obviously improve Improve Invalid Total improvement rate %
Embodiment 1 125 92 17 16 87.2
Embodiment 2 115 93 8 14 87.8
Embodiment 3 112 92 9 11 90.2
Embodiment 4 105 86 7 12 88.6
Embodiment 5 120 95 12 13 89.2
Matched group (Radix Ginseng) 40 4 18 18 55.0
Matched group (Stigma Croci) 50 5 21 24 52.0
Matched group (Cordyceps) 58 14 20 24 58.6
Matched group (Radix Ginseng+Stigma Croci) 60 15 27 18 70.0
Matched group (Radix Ginseng+Cordyceps) 67 20 29 18 73.1
Matched group (Stigma Croci+Cordyceps) 61 17 27 17 72.1
Drug side effect of the present invention: period in a medicine small number of patients xerostomia, outside the dry stool, all there is not any untoward reaction, drug withdrawal or decrement, mouthfeel, dry stool transference cure.
Test example 3: the present invention is to improving and promote the mice sleep test
Utilize preparation of the present invention (embodiment 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5) to its acute toxicity, three mutagenesis with improve sleep and detect; Draw following result: five preparations are to other SPF level Kunming mouse per os toxicity of both sexes; Once irritate the stomach amount and reach 10.0g/kg.bw, animal does not all see obvious poisoning symptom, no animal dead in the week; Press the acute toxicity grading criteria regulation, this animal subject belongs to nontoxic level.The result is all negative for three project mutagenicity tests (PCEMNR micronucleus test, mouse sperm deformity test, Salmonella reversion test); The feeding trial result showed in 30 days: this tried thing by 0.28,0.70,1.40g/kg.bw dosage (be equivalent to respectively recommend crowd's daily intaking amount 0.014g/kg.bw 20,50,100 times) all do not have obvious influence to the clinical examination of wistar rat, hematology, biochemical, organ weights and indexs such as coefficient and histopathology, do not find that animal subject has tangible toxic action;
Adopt SPF level kunming mice, tried thing continuously and improved sleep effect result of the test in 20 days and show: 1) this is tried the basic, normal, high dose groups of thing and is obviously prolonged the inductive mouse sleep time of threshold dose pentobarbital sodium, and difference has significance; 2) middle and high dose groups can obviously improve sub-threshold dose penta than the inductive mice sleep incidence rate of appropriate sodium, and difference has significance; 3) middle and high dose groups can obviously shorten the inductive mice sleep of barbital sodium incubation period, and difference has significance; Above result shows: this is tried thing and pentobarbital sodium, barbital sodium have collaborative sleep effect.Explain that compositions of the present invention has remarkable facilitation to the sleep of mice.
Test example 4: the present invention is to the influence test of mouse anti-reflecting fatigue
Preparation of the present invention (embodiment 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5, embodiment 6) is to mouse anti-reflecting fatigue influence test.Press the gastric infusion of dosage shown in the table 2, every day 1 time, continuous 10 days, normal control group and model group gave the equal-volume distilled water, and volume is 20ml/kg.And in first day on-test.After the last administration 1 hour, animal is put into 15 ± 1 ℃ swimming groove, observe mice and put into water and be sink to the water-bed unable again time of floating for continuing swimming time.The result sees that table 2. is visible by table 2 result, and compositions of the present invention can obviously prolong mice low temperature and continue swimming time.
Table 2. preparation of the present invention is to the influence of mice swimming time
Figure BDA0000156386370000071
Result of the test shows, but preparation significant prolongation mice low temperature of the present invention continues swimming time, shows that preparation of the present invention has resisting fatigue effect preferably to mice.
Test example 5: preparation of the present invention is to the clinical trial of impotence patient treatment
1, clinical data: the total number of persons of participating in test: 204 people, participate in the test age composition: 45 people below 30 years old, 31-40 year 73 people, 41-50 year 60 people, 51-60 year 47 people, 32 people more than 61 years old.Medical history is the longest 10 years, and is the shortest 2 months.Average course of disease 13.5 months.Need each age bracket to divide four groups according to test, respectively attend the demonstration test of four embodiment of the present invention.With the single agent capsules of Cordyceps is contrast, in the matched group, and 8 people below 30 years old, 31-40 year 10 people, 41-50 year 12 people, 51-60 year 11 people, 9 people more than 61 years old.Body is looked into: the sexual organ development is normal.Clinical main performance: cloudy essence can not normal erection during sexual life, can erect reluctantly though contact cloudy essence through stimulus to the sense organ or genitals, can not be strong, and the insertion vagina of can not being satisfied with, or insert the back and in 1-2 minute, wither soft.Or with waist urushic acid pain, dizziness and tinnitus, seminal emission, premature ejaculation, night frequent micturition, even cold syndrome of the stomach cold extremities, pale complexion.
2, Therapeutic Method: respectively obey 1 time each 3 grams sooner or later.15 days is a course of treatment, during the medication, does not add other drug.Symptom variation situation before and after observation, the record patient medication during the medication is carried out the clinical observation record weekly once, and at treatment front and back routine examination liver function, renal function, routine blood test etc.Contrast medicament: the single agent capsules of Cordyceps; Cordyceps+Panax Capsule (Cordyceps: Radix Ginseng=1: 1).
3, clinical observation
3.1 curative effect criterion of cure: cloudy smart ability normal erection when stimulus to the sense organ or genitals contact, accomplish normal sexual life process and can reach more than 5 minutes, follow up a case by regular visits to and do not have recurrence more than 1 year.Produce effects: stimulus to the sense organ can be erected but is not strong, and genitals contact often can normal erection and accomplished the sexual life process, but the time is in 3-5 minute.Effectively: can satisfy the insertion of penis basically, accomplish the sexual life process time and be no more than 3 minutes.Invalid: performance does not have obvious change before and after the treatment, can not accomplish normal sexual life.
3.2 therapeutic outcome the shortest 1 course of treatment, the longest 5 courses of treatment.Total effective rate all reaches 86% as a result, obviously is superior to contrasting medicament.
Table 3 all ages and classes therapeutic effect relatively
Figure BDA0000156386370000081
Figure BDA0000156386370000101
From table, can find out that the right side of fifty patient is respond well with preparation of the present invention, with advancing age, poor effect, its reason possibly be with advancing age, and body descends relevant to the reactivity of medicine.Show that preparation of the present invention has remarkable therapeutic effect to sexual impotence (curing mainly syndrome of deficiency of kidney-YANG).

Claims (7)

1. one kind has the collaborative Chinese medicine composition that improves human body immunity of organisms, resisting fatigue and effect of nourishing Yin and invigorating kidney, and it is characterized in that being made up of the raw material that comprises following weight parts: Radix Ginseng is 3-65 part, and Stigma Croci is 2-55 part, Cordyceps 4-60 part.
2. according to the compositions of claim 1, it is characterized in that in total active component, by weight: Radix Ginseng is 5-50 part, and Stigma Croci is 4-40 part, Cordyceps 5-45 part.
3. according to the compositions of claim 1, it is characterized in that in total active component, by weight: Radix Ginseng is 5-30 part, and Stigma Croci is 4-25 part, Cordyceps 5-30 part.
4. according to the compositions of claim 1, it is characterized in that described compositions is the preparation of peroral dosage form.
5. according to the compositions of claim 1-4, it is characterized in that described compositions improves the application in the immunity Chinese medicine in preparation.
6. according to the compositions of claim 1-4, it is characterized in that the application of described compositions in the preparation anti-fatigue Chinese medicine.
7. according to the compositions of claim 1-4, it is characterized in that described compositions has the application in the YIN nourishing and YANG strengthening Chinese medicine in preparation.
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CN103404871A (en) * 2013-07-01 2013-11-27 吉林省宏久生物科技股份有限公司 Red ginseng and cordyceps militaris beverage and preparation method thereof
CN104189283A (en) * 2014-09-04 2014-12-10 上海浦东高星生物技术研究所 Pomegranate seed oil drop pill
CN106334090A (en) * 2016-11-10 2017-01-18 西藏城宇生物科技有限公司 Traditional Chinese medicine composition for anti-fatigue and nourishing yin and tonifying yang and preparing method thereof
CN111759987A (en) * 2020-07-15 2020-10-13 赵艳玲 Traditional Chinese medicine composition for dredging blood vessels and channels and collaterals and preparation method and application thereof

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