CN108904774A - A kind of skin-protection type topical agent and preparation method thereof for treating pernio - Google Patents
A kind of skin-protection type topical agent and preparation method thereof for treating pernio Download PDFInfo
- Publication number
- CN108904774A CN108904774A CN201811113137.2A CN201811113137A CN108904774A CN 108904774 A CN108904774 A CN 108904774A CN 201811113137 A CN201811113137 A CN 201811113137A CN 108904774 A CN108904774 A CN 108904774A
- Authority
- CN
- China
- Prior art keywords
- parts
- pernio
- skin
- protection type
- topical agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to Chinese herb prevention technical fields, in particular to a kind of skin-protection type topical agent and preparation method thereof for treating pernio, medicament prepares raw material by Chinese medicine and solution composition, wherein each ingredient of Chinese medicine includes tabasheer, cassia seed, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis, jujube, prepared medicament can be applied directly at pernio swelling, had effects that quickly to reduce swelling and taken off silt.
Description
Technical field
The invention belongs to Chinese herb prevention technical field, in particular to a kind of skin-protection type topical agent for treating pernio and
Preparation method.
Background technique
Pernio is one of the common disease in winter, is human body hand, and foot, ear, the exposure portions such as face are by caused by attacked by the cold and evil
Locality damage, be in purplish red patch, swelling and pain, serious person may occur in which blister, ulcer.Pernio once occurs, in cold season
It is difficult rapid healing in section, and second year is also easy to recur.
Currently, mainly think in Chinese medicine pernio be stagnated due to cold-evil in fleshy exterior part, cause qi and blood it is obstructed caused by,
Although traditional Chinese medical science field avoids the use of antibiotic during curing to pernio, but warming channel and expelling cold, living in order to reach
The effect of blood dredging collateral still inevitably will use the medicine in the temperature of big heat of a part of great Xin etc in many drugs, for a long time
Drug using the big heat of great Xin is unfavorable to human body and skin, and the risk of pernio recurrence is still remained after medication.
Summary of the invention
In order to solve the above technical problems, the present invention provides a kind of for treating the skin-protection type topical agent of pernio, it is former
Included traditional Chinese medicine ingredients have tabasheer, cassia seed, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis, jujube in material,
In parts by weight, traditional Chinese medicine ingredients included in the raw material of medicament have 40~50 parts of tabasheer, cassia seed 7~
15 parts, 12~18 parts of mulberry leaf, 11~15 parts of Radix Salviae Miltiorrhizae, 6~10 parts of rheum officinale, 3~8 parts of ramulus cinnamomi, 5~11 parts of rhizoma zingiberis, jujube 20~30
Part.
The present invention also provides a kind of preparation methods of above-mentioned skin-protection type topical agent：Each traditional Chinese medicine ingredients are crushed to 60~
" tabasheer, cassia seed, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis, jujube " (due to being limited to by 100 mesh in this programme
" traditional Chinese medicine ingredients ", this has been drying regime when also just implying that these components are taken) it is latter with immerse ethyl alcohol aqueous solution in,
It is sealed 20 days or so, then filters, collect the skin-protection type topical agent that filtrate is this programme,
Wherein, in the aqueous solution of ethyl alcohol, the mass ratio of ethyl alcohol and water is 5：5~9：1,
The aqueous solution of ethyl alcohol is 120~160 parts in parts by weight.
The medicament of this programme is applied directly at pernio swelling, has effects that quickly to reduce swelling and takes off silt, and can have
Effect avoids pernio in the recurrence at the position, illustrates that the medicament has preferable deeply internal, removal old complaint curative effect.This programme institute
In the traditional Chinese medicine ingredients of selection based on medicinal material cold in nature, sweet in flavor or bitter, a large amount of hot drugs are avoided while promoting blood circulation and removing obstruction in channels
Side effect is brought to human body, has also mitigated the sense of discomfort of human body during the topical application of drug.
Specific embodiment
Embodiment 1
It is a kind of for treating the skin-protection type topical agent of pernio, which prepares raw material by the aqueous solution of Chinese medicine and ethyl alcohol
Composition, wherein each ingredient of Chinese medicine be in parts by weight 43 parts of tabasheer, 9 parts of cassia seed, 15 parts of mulberry leaf, 12 parts of Radix Salviae Miltiorrhizae,
10 parts of rheum officinale, 6 parts of ramulus cinnamomi, 8 parts of rhizoma zingiberis, 23 parts of jujube,
The tabasheer of the above parts by weight, cassia seed, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis, jujube are crushed to respectively
(mass concentration of ethyl alcohol be 85%) is immersed in the aqueous solution of the ethyl alcohol of 120 parts by weight after 80 mesh together, in room temperature (25 DEG C)
Under be sealed 22 days, then filter, collecting resulting filtrate is skin-protection type topical agent.
Embodiment 2
It is a kind of for treating the skin-protection type topical agent of pernio, which prepares raw material by the aqueous solution of Chinese medicine and ethyl alcohol
Composition, wherein each ingredient of Chinese medicine is 48 parts of tabasheer, 13 parts of cassia seed, 12 parts of mulberry leaf, Radix Salviae Miltiorrhizae 12 in parts by weight
Part, 6 parts of rheum officinale, 4 parts of ramulus cinnamomi, 10 parts of rhizoma zingiberis, 26 parts of jujube,
The tabasheer of the above parts by weight, cassia seed, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis, jujube are crushed to respectively
(mass concentration of ethyl alcohol be 85%) is immersed in the aqueous solution of the ethyl alcohol of 120 parts by weight after 80 mesh together, in room temperature (25 DEG C)
Under be sealed 25 days, then filter, collecting resulting filtrate is skin-protection type topical agent.
Comparative example 1
Compared to embodiment 1, tabasheer is not added, remaining component ratio and operation are the same as embodiment 1：
It is a kind of for treating the skin-protection type topical agent of pernio, which prepares raw material by the aqueous solution of Chinese medicine and ethyl alcohol
Composition, wherein each ingredient of Chinese medicine is 9 parts of cassia seed, 15 parts of mulberry leaf, 12 parts of Radix Salviae Miltiorrhizae, 10 parts of rheum officinale, osmanthus in parts by weight
Branch 6 parts, 8 parts of rhizoma zingiberis, 23 parts of jujube,
After the cassia seed of the above parts by weight, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis, jujube are crushed to 80 mesh respectively
It is immersed in the aqueous solution of the ethyl alcohol of 79 parts by weight (mass concentration of ethyl alcohol is 85%) together, seals and protects under room temperature (25 DEG C)
It deposits 22 days, then filters, collecting resulting filtrate is skin-protection type topical agent.
Comparative example 2
Compared to embodiment 1, cassia seed is not added, remaining component ratio and operation are the same as embodiment 1：
It is a kind of for treating the skin-protection type topical agent of pernio, which prepares raw material by the aqueous solution of Chinese medicine and ethyl alcohol
Composition, wherein each ingredient of Chinese medicine be in parts by weight 43 parts of tabasheer, 15 parts of mulberry leaf, 12 parts of Radix Salviae Miltiorrhizae, 10 parts of rheum officinale,
6 parts of ramulus cinnamomi, 8 parts of rhizoma zingiberis, 23 parts of jujube,
After the tabasheer of the above parts by weight, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis, jujube are crushed to 80 mesh respectively
It is immersed in the aqueous solution of the ethyl alcohol of 111 parts by weight (mass concentration of ethyl alcohol is 85%) together, is sealed under room temperature (25 DEG C)
It saves 22 days, then filters, collecting resulting filtrate is skin-protection type topical agent.
Comparative example 3
Compared to embodiment 1, the dosage of tabasheer and cassia seed is interchangeable, remaining component and operation are the same as embodiment 1：
It is a kind of for treating the skin-protection type topical agent of pernio, which prepares raw material by the aqueous solution of Chinese medicine and ethyl alcohol
Composition, wherein each ingredient of Chinese medicine be in parts by weight 9 parts of tabasheer, 43 parts of cassia seed, 15 parts of mulberry leaf, 12 parts of Radix Salviae Miltiorrhizae,
10 parts of rheum officinale, 6 parts of ramulus cinnamomi, 8 parts of rhizoma zingiberis, 23 parts of jujube,
The tabasheer of the above parts by weight, cassia seed, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis, jujube are crushed to respectively
(mass concentration of ethyl alcohol be 85%) is immersed in the aqueous solution of the ethyl alcohol of 120 parts by weight after 80 mesh together, in room temperature (25 DEG C)
Under be sealed 22 days, then filter, collecting resulting filtrate is skin-protection type topical agent.
Comparative example 4
Compared to embodiment 1, jujube is not added, remaining component ratio and operation are the same as embodiment 1：
It is a kind of for treating the skin-protection type topical agent of pernio, which prepares raw material by the aqueous solution of Chinese medicine and ethyl alcohol
Composition, wherein each ingredient of Chinese medicine be in parts by weight 43 parts of tabasheer, 9 parts of cassia seed, 15 parts of mulberry leaf, 12 parts of Radix Salviae Miltiorrhizae,
10 parts of rheum officinale, 6 parts of ramulus cinnamomi, 8 parts of rhizoma zingiberis,
The tabasheer of the above parts by weight, cassia seed, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis are crushed to 80 mesh respectively
It is immersed in the aqueous solution of the ethyl alcohol of 98 parts by weight (mass concentration of ethyl alcohol is 85%) together afterwards, is sealed under room temperature (25 DEG C)
It saves 22 days, then filters, collecting resulting filtrate is skin-protection type topical agent.
The patient for having pernio on 140 right hands (strong hand) is divided into 7 groups, when this 140 patient's winters in former years on the right hand
Suffered from pernio, wherein male 70, women 70, the age between 20 to 50 one full year of life, every group of 20 people (10 male after grouping
Property, 10 women), passive protective physical fitness, pernio position between group and group about patient age, usually, the size in pernio face, number
Amount, degree of injury etc. are distributed upper no significant difference in personnel amount,
When painting medicine, by pernio face with clean paper handkerchief wiped clean, after dipping medicament with clean cotton uniformly
Coated on pernio face, pernio face applies three times on time daily without ulcer symptoms, and there is the every of ulcer or blister symptom in pernio face
It applies on time day five times (being changed to three times a day after to wound incrustation), it is natural on pernio face to medicament without wiping after coating
Dry, uninterrupted coating is until pernio healing (healing standard：Swelling is eliminated, painless, and skin restores normal or only a small amount of
Pigmentation).The comparison between each group, each patient are carried out by recording recovery situation of each patient during the lasting topical application of drug
Everyone each topical application of drug amount is identical, during the topical application of drug, the social activitieies such as each patient works as usual, learns, and
During the topical application of drug, each patient does not occur the disease in terms of the resistances such as flu, fever,
The patient of coating 1 medicament of above embodiments is included into first group,
The patient of coating 2 medicament of above embodiments is included into second group,
The patient for applying above 1 medicament of comparative example is included into third group,
The patient for applying above 2 medicament of comparative example is included into the 4th group,
The patient for applying above 3 medicament of comparative example is included into the 5th group,
The patient for applying above 4 medicament of comparative example is included into the 6th group,
The patient for not carrying out pharmaceutical intervention is included into the 6th group, as control,
Table 1 has recorded the patient of corresponding number in each group from painting medicine is started to pernio healing time (day experienced
Number), the time that control group starts the topical application of drug with first group starts timing：
Table 1
From the point of view of the statistical result of upper table, when tabasheer and cassia seed collaboration are used as medicine, have to pernio face and well disappear
The effect of swollenization silt and anti-inflammatory.
5th group (comparative example 3) is also that tabasheer and cassia seed collaboration are used as medicine, in effect compared to third group and
4th group has progress, but is still far below embodiment 1, the curative effect of embodiment 2, exists it is applicant's understanding that being likely to be cassia seed
The effect of efficacy-enhancing ingredient is functioned similarly in the Chinese drugs agentia of this programme, after tabasheer dosage significantly reduces, although as " efficacy-enhancing ingredient "
There are many cassia seed dosage, but still occur corresponding decline in curative effect；And the case where from the 6th group (comparative example 4), comes
It sees, other components also have more apparent influence to the curative effect of this programme medicament.
And the patient coated by the medicament Jing Guo embodiment 1, embodiment 2 in first group, second group, second year winter are right
Recurring the number of pernio on hand is respectively 4 people and 1 people, and recurrence rate is very low.
Claims (6)
1. a kind of for treating the skin-protection type topical agent of pernio, it is characterised in that：In included by the raw material of the medicament
Medicine ingredient has tabasheer, cassia seed, mulberry leaf, Radix Salviae Miltiorrhizae, rheum officinale, ramulus cinnamomi, rhizoma zingiberis, jujube.
2. as described in claim 1 for treating the skin-protection type topical agent of pernio, it is characterised in that：It is wrapped in the raw material
The traditional Chinese medicine ingredients included have 40~50 parts of tabasheer, 7~15 parts of cassia seed, 12~18 parts of mulberry leaf, Radix Salviae Miltiorrhizae 11 in parts by weight
~15 parts, 6~10 parts of rheum officinale, 3~8 parts of ramulus cinnamomi, 5~11 parts of rhizoma zingiberis, 20~30 parts of jujube.
3. a kind of as claimed in claim 1 or 2 for treating the preparation method of the skin-protection type topical agent of pernio, feature exists
In：The preparation method is,
It is immersed in the aqueous solution of ethyl alcohol together after each traditional Chinese medicine ingredients are crushed, then sealed preservation processing filters, collects filter
Liquid is the skin-protection type topical agent.
4. as claimed in claim 3 for treating the preparation method of the skin-protection type topical agent of pernio, it is characterised in that：It will be each
Traditional Chinese medicine ingredients are crushed to 60~100 mesh.
5. as claimed in claim 3 for treating the preparation method of the skin-protection type topical agent of pernio, it is characterised in that：It is described
Ethyl alcohol aqueous solution in, the mass ratio of ethyl alcohol and water is 5：5~9：1.
6. as claimed in claim 3 for treating the preparation method of the skin-protection type topical agent of pernio, it is characterised in that：Sealing
It saves 18 to 25 days.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811113137.2A CN108904774A (en) | 2018-09-25 | 2018-09-25 | A kind of skin-protection type topical agent and preparation method thereof for treating pernio |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811113137.2A CN108904774A (en) | 2018-09-25 | 2018-09-25 | A kind of skin-protection type topical agent and preparation method thereof for treating pernio |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108904774A true CN108904774A (en) | 2018-11-30 |
Family
ID=64408739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811113137.2A Pending CN108904774A (en) | 2018-09-25 | 2018-09-25 | A kind of skin-protection type topical agent and preparation method thereof for treating pernio |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108904774A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013185294A1 (en) * | 2012-06-12 | 2013-12-19 | Nie Pingsheng | Chinese medicine for preventing and treating rhagades and frostbite and preparation method thereof |
| CN105214065A (en) * | 2015-11-16 | 2016-01-06 | 于永生 | External chilblain is loose, preparation technology and using method thereof |
-
2018
- 2018-09-25 CN CN201811113137.2A patent/CN108904774A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013185294A1 (en) * | 2012-06-12 | 2013-12-19 | Nie Pingsheng | Chinese medicine for preventing and treating rhagades and frostbite and preparation method thereof |
| CN105214065A (en) * | 2015-11-16 | 2016-01-06 | 于永生 | External chilblain is loose, preparation technology and using method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103055052B (en) | Cream for treating burn and scald and preparation method of cream | |
| CN104547188A (en) | External preparation for treating varicosity and preparation method thereof | |
| CN100386106C (en) | Medicine for treating acne and its preparation | |
| CN102552520B (en) | Blood circulation-promoting and pain-stopping medicament and preparation process and application thereof | |
| CN104984180A (en) | Traditional Chinese medicine combination for treating gout and preparing method thereof | |
| CN108904774A (en) | A kind of skin-protection type topical agent and preparation method thereof for treating pernio | |
| CN103638193B (en) | A kind of Chinese medicine for acne and preparation method thereof | |
| CN105169294A (en) | Traditional Chinese medicine ointment for treating scapulohumeral periarthritis | |
| CN103520447A (en) | Externally used ointment suitable for anal fistula after operation | |
| CN103877557B (en) | A kind of Chinese medicine ointment and preparation method for the treatment of tinea unguium | |
| CN103721028B (en) | One treats anginal medicine and preparation method | |
| CN103599386B (en) | A kind of Chinese medicine composition for diabetes | |
| CN106109927A (en) | A kind of pharmaceutical composition treating chloasma and preparation method thereof | |
| CN102205057B (en) | Preparation method of traditional Chinese medicine for treating conjunctival congestion type infant influenza | |
| CN108567880B (en) | Arthralgia relieving tincture as well as preparation method and application thereof | |
| CN105663850A (en) | Traditional Chinese medicine composition for treating oral ulcer | |
| CN1883592A (en) | Gel for treating rheumatism and headache and method for preparing same | |
| CN105456718A (en) | Medicinal extract for curing radiodermatitis and preparation thereof | |
| CN104784285A (en) | Traditional Chinese medicine ointment for treating rosacea | |
| CN1132588C (en) | Chinese patent medicine for treating gastrosis and its preparing process | |
| CN104825919B (en) | A kind of herb liquid for treating AIDS fever | |
| CN102885950B (en) | Pharmaceutical composition for treating cervix uteri postoperative bleeding | |
| CN102698195B (en) | Radix-curcumae traditional Chinese medicinal oral liquid for treating chronic hepatitis and preparation method | |
| CN103393926B (en) | A kind of medicine for the treatment of chronic bronchitis and preparation method thereof | |
| CN102526689B (en) | Preparation method of traditional Chinese medicinal lotion for treating wind-cold type ecthyma |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181130 |