CN104825919B - A kind of herb liquid for treating AIDS fever - Google Patents
A kind of herb liquid for treating AIDS fever Download PDFInfo
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- CN104825919B CN104825919B CN201510238689.6A CN201510238689A CN104825919B CN 104825919 B CN104825919 B CN 104825919B CN 201510238689 A CN201510238689 A CN 201510238689A CN 104825919 B CN104825919 B CN 104825919B
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract
The present invention relates to the herb liquids for the treatment of AIDS fever, effectively solve the problems, such as the medication for the treatment of AIDS fever, it is made of 122 150g of vinegar Bupleurum Chinese, 81 101g of Pogostemon cablin, 122 150g of coix seed, 81 101g of Semen Arecae (parched), 245 301g of talcum powder, 81 101g of rhizoma anemarrhenae, 122 150g of radix scutellariae and 40 50g of Radix Glycyrrhizae, vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) mixing, add water, distillation, collects distillate, and the another device of aqueous solution after distillation is deposited；The dregs of a decoction are mixed with coix seed, talcum powder, rhizoma anemarrhenae, radix scutellariae and Radix Glycyrrhizae, add water, are decocted, decocting liquid and aqueous solution mix, and filter, concentration, centrifugation, liquid add sodium benzoate and honey element, are mixed with above-mentioned distillate, it stirs evenly, adds water, the present invention can not only treat the problem of AIDS is generated heat, pestilence can also be treated, drug safety is stablized, convenient to take, it is easy to absorb, has no toxic side effect, effect is good.
Description
Technical field
The present invention relates to field of medicaments, particularly a kind of herb liquid for treating AIDS fever（Also known as the bavin leaves of pulse plants is closed up to former
Agent）.
Background technology
AIDS is widely distributed in countries in the world, and treatment difficulty is big, and serious threat the health and life security of people, warp
Clinical epidemiological study, AIDS crowd are increasing.AIDS patient lowly easily occurs seriously due to body's immunity
Opportunistic infections fever, and it is not to die of primary disease that AIDS patient is mostly final, is to die of opportunistic infections, opportunistic
One of an important factor for one of symptom of infection is fever, and the treatment to opportunistic infections fever is its death rate of reduction.Heresy volt
The former card of film is the common type of its fever.The clinical visible high fever loathing of cold is sent out without timing, chest tightness and emesis, headache agitation etc..But
Western medicine is still without targeted drug at present, therefore the Chinese medicine for how developing treatment AIDS fever is that crowd is expected.
The content of the invention
For the above situation, to overcome prior art defect, AIDS hair is treated it is an object of the invention to provide a kind of
The herb liquid of heat can effectively solve the problems, such as the medication for the treatment of AIDS fever.
The technical solution that the present invention solves is, by weight meter：Vinegar Bupleurum Chinese 122-150g, Pogostemon cablin 81-101g, the heart of a lotus seed
Seed of jog's tears 122-150g, Semen Arecae (parched) 81-101g, talcum powder 245-301g, rhizoma anemarrhenae 81-101g, radix scutellariae 122-150g and Radix Glycyrrhizae 40-
50g is made of material medicine, wherein, vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) mixing add vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched)
The water of 7-9 times of weight distills 2.5-3.5h, and collection distillate is spare, and the another device of the aqueous solution after distillation preserves；The dregs of a decoction and Job's tears
Benevolence, talcum powder, rhizoma anemarrhenae, radix scutellariae and Radix Glycyrrhizae mixing add the water of 5-7 times of material medicine weight, decoct three times, and each 1-2h merges
Decocting liquid, decocting liquid and the mixing of above-mentioned aqueous solution, filtration under the conditions of pressure 0.6-0.7 MPa, temperature 70 C, are concentrated into 500-
600ml, centrifugation, liquid add in the sodium benzoate and 0.3% honey element of liquid weight 0.3%, mix, stir evenly with above-mentioned distillate,
Add water that the herb liquid for being equivalent to the 0.9-1g/ml containing crude drug amount is made.
The present invention has relieving Moyuan, wards off the effect of dirtyization is turbid, can not only treat the problem of AIDS is generated heat, can be with
For treating pestilence, drug safety is stablized, convenient to take, is easy to absorb, have no toxic side effect, effect is good.
Specific embodiment
It elaborates with reference to embodiments to the specific implementation method of the present invention.
Embodiment 1
The present invention is by weight meter：Vinegar Bupleurum Chinese 136g, Pogostemon cablin 91g, coix seed 136g, Semen Arecae (parched) 91g, talcum
Powder 273g, rhizoma anemarrhenae 91g, radix scutellariae 136g and Radix Glycyrrhizae 45g are made of material medicine, wherein, vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) mix
It closes, adds the water of 8 times of vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) weight, distill 3h, collection distillate is spare, the aqueous solution after distillation
Another device preserves；The dregs of a decoction are mixed with coix seed, talcum powder, rhizoma anemarrhenae, radix scutellariae and Radix Glycyrrhizae, add the water of 6 times of material medicine weight, decoct three
Secondary, each 1.5h, collecting decoction, decocting liquid and above-mentioned aqueous solution are mixed, filtered, under the conditions of 0.6 MPa of pressure, temperature 70 C,
550ml is concentrated into, is centrifuged, liquid adds in 0.3% sodium benzoate of liquid weight and 0.3% honey element, mixes, stirs with above-mentioned distillate
It is even, add water that the herb liquid for being equivalent to the 0.9g/ml containing crude drug amount is made.
Embodiment 2
The present invention is by weight meter：Vinegar Bupleurum Chinese 122g, Pogostemon cablin 81g, coix seed 122g, Semen Arecae (parched) 81g, talcum powder
245g, rhizoma anemarrhenae 81g, radix scutellariae 122g and Radix Glycyrrhizae 40g are made of material medicine, wherein, vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) mix
It closes, adds the water of 7 times of vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) weight, distill 2.5h, collection distillate is spare, water-soluble after distillation
The another device of liquid preserves；The dregs of a decoction are mixed with coix seed, talcum powder, rhizoma anemarrhenae, radix scutellariae and Radix Glycyrrhizae, add the water of 5 times of material medicine weight, are decocted
Three times, each 1h, collecting decoction, decocting liquid and the mixing of above-mentioned aqueous solution, filtration, under the conditions of 0.6 MPa of pressure, temperature 70 C,
500ml is concentrated into, is centrifuged, liquid adds in the sodium benzoate and 0.3% honey element of liquid weight 0.3%, is mixed with above-mentioned distillate,
It stirs evenly, adds water that the herb liquid for being equivalent to the 0.9g/ml containing crude drug amount is made.
Embodiment 3
The present invention is by weight meter：Vinegar Bupleurum Chinese 150g, Pogostemon cablin 101g, coix seed 150g, Semen Arecae (parched) 101g, talcum
Powder 301g, rhizoma anemarrhenae 101g, radix scutellariae 150g and Radix Glycyrrhizae 50g are made of material medicine, wherein, vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched)
Mixing adds the water of 9 times of vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) weight, distills 3.5h, collection distillate is spare, the water after distillation
The another device of solution preserves；The dregs of a decoction are mixed with coix seed, talcum powder, rhizoma anemarrhenae, radix scutellariae and Radix Glycyrrhizae, add the water of 7 times of material medicine weight, are decocted
It boils three times, each 2h, collecting decoction, decocting liquid and the mixing of above-mentioned aqueous solution, filtration, in 0.7 MPa of pressure, temperature 70 C condition
Under, 600ml is concentrated into, is centrifuged, liquid adds in the sodium benzoate and 0.3% honey element of liquid weight 0.3%, is mixed with above-mentioned distillate
It closes, stirs evenly, add water that the herb liquid for being equivalent to the 1g/ml containing crude drug amount is made.
More than drug, wherein：
Vinegar Bupleurum Chinese：Bupleurum Chinese is taken, cuts into slices, is mixed thoroughly with vinegar, puts in pot and is exhausted and micro- dry with being fried with slow fire vinegar, taken out, solarization
Dry, per 100 jin of radix bupleuri, with 12 jin of vinegar, radix bupleuri evacuation is brought down a fever, soothing liver-qi stagnation, yang invigorating, have it is calm, stable, ease pain, be antipyretic,
The extensive central inhibitory action such as antibechic.Radix bupleuri decoction has tubercle bacillus inhibitory action, and bupleurum Chinense volatile oil has anti-common cold virus
Effect.
Pogostemon cablin：Dampness elimination, relieving summer-heat, preventing or arresting vomiting, volatile oil can promote gastric secretion to enhance eupepsy in Pogostemon cablin, have to stomach and intestine
Spasmolysis has anti-corrosion and antibacterial action, there is astringing to arrest diarrhea in addition, expands capilary and has perspiration.
Coix seed：Coix seed is taken, impurity is removed, dries, coix seed clearing damp and promoting diuresis, invigorating the spleen, eliminating impediment, clearing away heat and eliminating pus, can hinder
Only or band muscular contraction is reduced, to uterus in excitation, fat oil can make serum calcium, blood glucose amount decline, and have antipyretic, town
Quiet, analgesic activity.
Semen Arecae (parched)：Betel nut is taken, is cut into slices, is put in pot, be fried with slow fire pico- discoloration, takes out, cools, betel nut expelling parasites and food tagnancy, row
Gas Li Shui, arecaline, which has, intends choline effect, excited choline receptor, promotion saliva, sweat gland secretion, increase enterocinesia, reducing heart rate,
The effects that reducing blood pressure.
Talcum powder：Promoting diuresis for stranguria, removing summer-heat, hygroscopic sore play town when for oral administration except the gastrointestinal mucosa of protection inflammation
It spits, outside anti-diarrhea effect, moreover it is possible to prevent poisonous substance in the moderate absorption of stomach and intestine, there is inhibition to make typhoid bacillus and paratyphoid A bacillus
With；There is slight bacteriostasis to meningococcus.
Rhizoma anemarrhenae：Clearing heat-fire, nourishing Yin and moistening dryness, zoopery prove that rhizoma anemarrhenae has apparent antipyretic, eliminating the phlegm, diuresis, hypoglycemic
Effect, has the various pathogens such as shigella dysenteriae, Diplococcus pneumopniae different degrees of inhibitory action.
Radix scutellariae：Heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, tocolysis has anti-inflammatory antiallergic action, to shigella dysenteriae, diphtheria bar
Bacterium, Pseudomonas aeruginosa, staphylococcus, streptococcus, Diplococcus pneumopniae and meningococcus etc. have inhibitory action, and vaccine is caused
Rabbit vein 4~6 milliliters of the 6% radix scutellariae preserved material of injection of fever, there is refrigeration function, in addition has decompression, diuresis, adjusts blood fat blood
The effects that sugar and courage and spasmolysis.
Radix Glycyrrhizae：Invigorating middle warmer and replenishing QI, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, mediation property of medicine, extract of licorice root and enoxolone
There are apparent antibechic, phlegm-dispelling functions, Radix Glycyrrhizae is also anti-inflammatory, anti-allergic effects.
From said medicine, compatibility of the present invention is scientific and reasonable, has relieving Moyuan, wards off the effect of dirtyization is turbid, and through facing
Bed application achieves the effect of good, and specific relevant information is as follows：
1st, case selection
1.1 diagnostic criteria：Through making a definite diagnosis the patient of aids infection poison, with reference to Zheng Xiao cornels《New Chinese medicine clinical research refers to
Lead principle》（2002）Formulate the clinical research instruction principle page 186 of new Chinese medicine treatment influenza.Classical symptom：Fever
The loathing of cold, chest tightness and emesis, headache is irritated, and wiry and frequent pulse, tongue side is dark red, and tongue coating dirt is greasy or tongue Bai Houru accumulated powders.
1.2 include case standard it is all meet this disease diagnosis and Standards of Chinese Medical Syndrome Differentiation person, clinical observation case history can be included.
1.3 Excluded cases standards
1.3.1 the age below 18 one full year of life or more than 65, gestation or women breast-feeding their children.Those who are allergic to this drug.
1.3.2 the severe primaries disease patient such as angiocarpy, liver, kidney and hemopoietic system, mental patient are associated with.
1.3.3 it is all not meet inclusion criteria, not by regulation medication, it can not judge that curative effect or data be not congruent and affect the treatment
With security judgement person.
2nd, therapeutic scheme：Chinese medicine of the present invention is taken orally, 3 times a day, each 20ml, 7 days as one therapeutic course, 4 course for the treatment of statistics treatments
Effect.
3rd, observation index
3.1 curative effect determinate standard
3.1.1 recovery from illness：The fever loathing of cold, chest tightness and emesis, irritated symptom of having a headache disappear；
It is 3.1.2 effective：Symptom is substantially reduced；
3.1.3 effectively：Symptom mitigates；
It is 3.1.4 invalid：Symptom is not any change before relatively treating.
3.2 health giving quality observation indexs
3.2.1 generate heat, the 3.2.2 loathing of cold, 3.2.3 3.2.4 evil of vomitting uncomfortable in chest.
4th, statistical procedures
To 108 patients made a definite diagnosis, wherein male 56, women 52 is 18~65 years old age, 39.7 years old average.The course of disease 1
It is 7.2 days average to 15 days.
4.1 Chinese medicine treatment clinical efficacies using the present invention：It is shown in Table 1
Clinical efficacy after table 1 is treated（%）
| Number of cases | Recovery from illness | It is effective | Effectively | It is invalid | Total effective rate % |
| 108 | 48 | 32 | 18 | 10 | 91 |
4.2 pretherapy and post-treatment cardinal symptom variations：It is shown in Table 2
4.3 adverse reaction：More than patient is without any adverse reactions during treatment.
5）, model case
1st, Wu, man, 50 years old, the may be infected time：Nineteen ninety-five；Make a definite diagnosis the time：Aids infection poison in 2003；Infection way
Footpath：Paid blood donor participates in treatment PROJECT TIME：In October, 2004.First visit symptom：Fever is sent out without timing.It is weak, chest tightness and emesis,
Headache, wiry and frequent pulse, tongue is red, and tongue coating dirt is greasy.Tcm diagnosis is syndrome of pathogen hidden in moyuan.It is advised to take orally Chinese medicine of the present invention, 3 times a day, one
Secondary 20ml.It continuously takes 4 course for the treatment of, the symptoms such as fever, weak disappear, and diet increases, and have no that bad hair should.
6）, conclusion
In conclusion the present invention is by clinical test for many years, takes into account and ward off that dirtyization be turbid, relieving Moyuan, that develops is directed to
The prescription of AIDS fever, can not only treat the problem of AIDS is generated heat, and can be also used for treatment pestilence, and drug safety is treated
Effect is stablized, and has no toxic side effect, quick, good effect, is played in the theory of traditional Chinese medicine AIDS diagnosis and treatment and clinical innovation level
Leading role has potential huge value for clinical application, and with huge society and economic benefit.
Claims (4)
1. a kind of herb liquid for treating AIDS fever, which is characterized in that by weight meter：Vinegar Bupleurum Chinese 122-150g, the wide leaves of pulse plants
Fragrant 81-101g, coix seed 122-150g, Semen Arecae (parched) 81-101g, talcum powder 245-301g, rhizoma anemarrhenae 81-101g, radix scutellariae 122-
150g and Radix Glycyrrhizae 40-50g are made of material medicine, wherein, vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) mixing add vinegar Bupleurum Chinese, wide
Wrinkled giant hyssop and the water of 7-9 times of Semen Arecae (parched) weight distill 2.5-3.5h, and collection distillate is spare, and the another device of the aqueous solution after distillation preserves；
The dregs of a decoction are mixed with coix seed, talcum powder, rhizoma anemarrhenae, radix scutellariae and Radix Glycyrrhizae, add the water of 5-7 times of material medicine weight, are decocted three times, every time
1-2h, collecting decoction, decocting liquid and the mixing of above-mentioned aqueous solution, filtration, under the conditions of pressure 0.6-0.7MPa, temperature 70 C, concentration
To 500-600ml, centrifugation, liquid adds in the sodium benzoate and 0.3% honey element of liquid weight 0.3%, is mixed with above-mentioned distillate,
It stirs evenly, adds water that the herb liquid for being equivalent to the 0.9-1g/ml containing crude drug amount is made.
2. the herb liquid for the treatment of AIDS fever according to claim 1, which is characterized in that by weight meter：Vinegar north bavin
Hu 136g, Pogostemon cablin 91g, coix seed 136g, Semen Arecae (parched) 91g, talcum powder 273g, rhizoma anemarrhenae 91g, radix scutellariae 136g and Radix Glycyrrhizae 45g
It is made of material medicine, wherein, vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) mixing add vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) weight
8 times of water distills 3h, and collection distillate is spare, and the another device of the aqueous solution after distillation preserves；The dregs of a decoction and coix seed, talcum powder are known
Female, radix scutellariae and Radix Glycyrrhizae mixing add the water of 6 times of material medicine weight, decoct three times, each 1.5h, collecting decoction, decocting liquid and above-mentioned
Aqueous solution mixes, and filtration under the conditions of 0.6 MPa of pressure, temperature 70 C, is concentrated into 550ml, centrifuges, and liquid adds in liquid weight
0.3% sodium benzoate and 0.3% honey element are measured, mixes, stirs evenly with above-mentioned distillate, water is added to be made and is equivalent to 0.9g/ containing crude drug amount
The herb liquid of ml.
3. the herb liquid for the treatment of AIDS fever according to claim 1, which is characterized in that by weight meter：Vinegar north bavin
Hu 122g, Pogostemon cablin 81g, coix seed 122g, Semen Arecae (parched) 81g, talcum powder 245g, rhizoma anemarrhenae 81g, radix scutellariae 122g and Radix Glycyrrhizae 40g
It is made of material medicine, wherein, vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) mixing add vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) weight
7 times of water distills 2.5h, and collection distillate is spare, and the another device of the aqueous solution after distillation preserves；The dregs of a decoction and coix seed, talcum powder are known
Female, radix scutellariae and Radix Glycyrrhizae mixing add the water of 5 times of material medicine weight, decoct three times, each 1h, collecting decoction, decocting liquid and above-mentioned water
Solution mixes, and filtration under the conditions of 0.6 MPa of pressure, temperature 70 C, is concentrated into 500ml, centrifuges, and liquid adds in liquid weight
0.3% sodium benzoate and 0.3% honey element, mix with above-mentioned distillate, stir evenly, and water is added to be made and is equivalent to 0.9g/ containing crude drug amount
The herb liquid of ml.
4. the herb liquid for the treatment of AIDS fever according to claim 1, which is characterized in that by weight meter：Vinegar north bavin
Hu 150g, Pogostemon cablin 101g, coix seed 150g, Semen Arecae (parched) 101g, talcum powder 301g, rhizoma anemarrhenae 101g, radix scutellariae 150g and Radix Glycyrrhizae
50g is made of material medicine, wherein, vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched) mixing add vinegar Bupleurum Chinese, Pogostemon cablin and Semen Arecae (parched)
The water that 9 times of weight distills 3.5h, and collection distillate is spare, and the another device of the aqueous solution after distillation preserves；The dregs of a decoction and coix seed, talcum
Powder, rhizoma anemarrhenae, radix scutellariae and Radix Glycyrrhizae mixing, add the water of 7 times of material medicine weight, decoct three times, each 2h, collecting decoction, decocting liquid and
Above-mentioned aqueous solution mixing, filtration under the conditions of 0.7 MPa of pressure, temperature 70 C, are concentrated into 600ml, centrifuge, and liquid adds in medicine
The sodium benzoate of liquid weight 0.3% and 0.3% honey element, mix with above-mentioned distillate, stir evenly, and water is added to be made and is equivalent to containing crude drug amount
The herb liquid of 1g/ml.
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| JP3195916B2 (en) * | 1993-09-02 | 2001-08-06 | 株式会社雪国まいたけ | Agent for suppressing or increasing the number of helper T cells in AIDS |
| CN101450173B (en) * | 2007-12-07 | 2011-09-21 | 湖南炎帝生物工程有限公司 | Traditional Chinese medicine composition and preparation method and use thereof |
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Address after: No. 19, people's road, Zhengzhou, Henan Province, Henan Applicant after: The First Affiliated Hospital of Henan University of traditional Chinese Medicine Address before: No. 19, people's road, Zhengzhou, Henan Province, Henan Applicant before: THE FIRST AFFILIATED HOSPITAL OF HENAN INSTITUTE OF CHINESE MEDICINE |
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Inventor after: Xu Liran Inventor after: Guo Huijun Inventor after: Song Xiyuan Inventor after: Zhang Shixi Inventor after: Li Liangping Inventor after: Zheng Zhipan Inventor after: Duan Xiaoying Inventor after: Lei Ken Inventor before: Xu Liran Inventor before: Guo Huijun Inventor before: Song Xiyuan Inventor before: Zhang Shixi Inventor before: Li Liangping Inventor before: Zheng Zhipan Inventor before: Duan Xiaoying Inventor before: Lei Ken |
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