CN103638193B - A kind of Chinese medicine for acne and preparation method thereof - Google Patents
A kind of Chinese medicine for acne and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for acne and preparation method thereof.Chinese medicine for acne of the present invention, is made up of the raw material of Chinese medicine medicine of following weight portion: leaf 15-25 part of washing the dishes, Flos Trollii 8-16 part, Herba Boenninghauseniae 8-16 part, Cortex Phellodendri 8-16 part, Radix Salviae Miltiorrhizae 3-9 part, Radix Angelicae Sinensis 8-16 part, Fructus Forsythiae 8-16 part, Radix Angelicae Dahuricae 3-9 part, Spica Prunellae 3-9 part, Spina Gleditsiae 3-9 part, Concha Margaritifera 6-12 part, Catharsii molossi 3-9 part.Chinese medicine for acne of the present invention, has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, effect of promoting blood circulation to remove blood stasis, and for various types of acne, instant effect, cure rate is high, has no adverse reaction.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for acne and preparation method thereof.
Background technology
Acne, also known as " comedo ", " skin sore ", " acne ", is that one is not easily cured, the dermatosis that sickness rate is very high.Doctor trained in Western medicine thinks that acne is a kind of with the inertia diseases associated with inflammation of multifactor, the pleomorphism erythra hair follicle sebum structure that is feature, primary growth, in adolescence's face, breast, the more rich position of back sebaceous gland, shows as acne, inflammation pimple, pustule, tuberosity, cyst and cicatrix.The cause of disease of acne mainly contains: bacteriological infection, as the infection of corynebacterium acnes; Dyshormonia, as Serum Testosterone Levels improves; Metabolism disorder, as vigorous in fat secretion; Gastroenteropathy etc.The traditional Chinese medical science thinks that this disease is that, blood stasis dry by damp and hot blood stagnates skin, in addition drinking and eating irregularly, eats well delicious food savoury, pungent, Chong and Ren channel disorder, lung stomach-fire disturb on containing women's head-ornaments or because of taste have damp and hot caused by.
The method of current integrative therapy acne is Drug therapy.The treatment of doctor trained in Western medicine to non-inflammatory acne mainly uses retinoid compounds, as dimension A emulsifiable paste, or adopts antiandrogen class medicine, as spironolactone etc.; Mainly adopt antibiotic as erythromycin, spiramycin etc. to the treatment of inflammatory acne.The medicine that the traditional Chinese medical science adopts the mainly oral medicine such as heat-clearing and toxic substances removing, hard masses softening and resolving class decoction, pill, powder.
In existing, western medical treatment method exist subject matter be:
1. cure rate is lower.There is certain effect during medication often, occur repeatedly after drug withdrawal.
2. there is certain side effect.Untoward reaction is had after some patients medication, as weak in menoxenia, limbs etc.
3. the course for the treatment of is longer.Be generally 3-6 month.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of Chinese medicine for acne and preparation method thereof.
The present invention is realized by following technical scheme:
For a Chinese medicine for acne, be made up of the raw material of Chinese medicine medicine of following weight portion: leaf 15-25 part of washing the dishes, Flos Trollii 8-16 part, Herba Boenninghauseniae 8-16 part, Cortex Phellodendri 8-16 part, Radix Salviae Miltiorrhizae 3-9 part, Radix Angelicae Sinensis 8-16 part, Fructus Forsythiae 8-16 part, Radix Angelicae Dahuricae 3-9 part, Spica Prunellae 3-9 part, Spina Gleditsiae 3-9 part, Concha Margaritifera 6-12 part, Catharsii molossi 3-9 part.
Preferably, the above-mentioned Chinese medicine for acne, is made up of the raw material of Chinese medicine medicine of following weight portion: leaf 18-22 part of washing the dishes, Flos Trollii 10-14 part, Herba Boenninghauseniae 10-14 part, Cortex Phellodendri 10-14 part, Radix Salviae Miltiorrhizae 5-7 part, Radix Angelicae Sinensis 10-14 part, Fructus Forsythiae 10-14 part, Radix Angelicae Dahuricae 5-7 part, Spica Prunellae 5-7 part, Spina Gleditsiae 5-7 part, Concha Margaritifera 8-10 part, Catharsii molossi 5-7 part.
Preferred, the above-mentioned Chinese medicine for acne, is made up of the raw material of Chinese medicine medicine of following weight portion: 20 parts, the leaf that washes the dishes, Flos Trollii 12 parts, Herba Boenninghauseniae 12 parts, Cortex Phellodendri 12 parts, Radix Salviae Miltiorrhizae 6 parts, Radix Angelicae Sinensis 12 parts, Fructus Forsythiae 12 parts, the Radix Angelicae Dahuricae 6 parts, Spica Prunellae 6 parts, Spina Gleditsiae 6 parts, Concha Margaritifera 9 parts, Catharsii molossi 6 parts.
The above-mentioned Chinese medicine for acne, the dosage form of this Chinese medicine is external wash liquid.
The above-mentioned Chinese medicine external washing liquid preparation method for acne, comprises the steps:
A, takes various raw material according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 4-6 times amount soak by water 1.5-2.5 hour, second time adds injection volume 2-4 times amount soak by water 1-2 hour, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, and filter, sterilizing, to obtain final product.
Preferably, above-mentioned in the Chinese medicine external washing liquid preparation method of acne, decocting with water first time in process amount of water in described step c is 5 times of injection volume, decocts 2 hours; Second time amount of water is 3 times of injection volume, decocts 1 hour.
The above-mentioned Chinese medicine external washing liquid preparation method for acne, detailed step is as follows:
A, takes the leaf 20g that washes the dishes, Flos Trollii 12g, Herba Boenninghauseniae 12g, Cortex Phellodendri 12g, Radix Salviae Miltiorrhizae 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Radix Angelicae Dahuricae 6g, Spica Prunellae 6g, Spina Gleditsiae 6g, Concha Margaritifera 9g, Catharsii molossi 6g;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 5 times amount soak by water 2 hours, second time adds injection volume 3 times amount soak by water 1.5 hours, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, and filter, sterilizing, to obtain final product.
The leaf that washes the dishes is Solanaceae nightshade Radix solani coagulantis tree SolanumverbascifoliumL., is used as medicine with root and leaf.Return liver, stomach warp, kidney, spleen, lung, urinary bladder channel.There is heat-clearing and toxic substances removing, effect of wind-expelling pain-stopping.Clinically be used for the accumulation of heat stagnation of QI, epigastric pain; Rheumatic arthralgia, treating swelling and pain by traumatic injury.
Flos Trollii has another name called Flos Trollii, another name: non-irrigated lotus, Herba Tropaeoli tremble with fear lotus, land lotus, nonirrigated farmland lotus, globe-flower, golden pimple, are the herb heat-clearing and toxic substances removing that ranunculaceae plant Flos Trollii TrolliuschinensisBunge is.Clinically be usually used in upper respiratory tract infection, tonsillitis, pharyngitis, acute otitis media, acute myringitis, acute conjunctivitis, acute lymphangitis, aphtha, furuncle.
Herba Boenninghauseniae another name winged steed, sheep do not eat, nine N of two Herba Saxifragae, sheep have a strong smell grass, copper foot Herba Achilleae, Kochia scoparia (, be the herb of Rutaceae pine wind grass platymiscium Herba Boenninghauseniae BoenninghauseniasessilicarpaLevl..Autumn extracts herb, and clean cutting is dried.Bitter, pungent, cool.Slightly poisonous.There is heat-clearing and toxic substances removing, effect of promoting blood circulation and stopping pain.Clinical being usually used in catches a cold, tonsillitis, parotitis, bronchitis, stomachache abdominal distention, thromboangiitis obliterans, lumbago, traumatic injury.
Catharsii molossi is the dry Scorpio of coleoptera Scarabaeidae insecticide Catharsii molossi CatharsiusmolossusL..Salty, cold.Nontoxic.There is removing toxic substances, detumescence, effect of relieving constipation.Clinically be used for sore swollen toxin, anal fistula, constipation.
Other Cortex Phellodendri, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae, Concha Margaritifera are Chinese Pharmacopoeia 2010 editions medical materials recorded.
The usage and dosage of lotion of medication of the present invention is: boil temperature with the lotion of medication of the present invention of 20% concentration (namely getting this product 100ml warm water to 500ml, mixing) and smoke and wash acne spots; 2-3 time on the one 10 days is a course for the treatment of.
Chinese medicine for acne of the present invention, has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, effect of promoting blood circulation to remove blood stasis, for various types of acne.
Chinese medicine for acne of the present invention, compatibility is reasonable, and prescription is precise and appropriate.Full side has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, effect of blood circulation promoting and blood stasis dispelling, and wash the dishes in side leaf, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Spina Gleditsiae, Concha Margaritifera heat-clearing and toxic substances removing, and dampness is subsided a swelling; Radix Salviae Miltiorrhizae removing heat from blood and promoting blood circulation, Radix Angelicae Sinensis, Catharsii molossi promoting blood circulation to remove obstruction in the collateral.Take a broad view of full side, medication is precise and appropriate, and compatibility is rigorous, and all medicines share, and hit pathogenesis, plays effect of heat clearing and damp drying, promoting blood circulation to remove blood stasis, removing toxic substances and promoting subsidence of swelling altogether.For various types of acne, to the acne of the various degree for the treatment of, eliminate corresponding symptom and there is good result.In addition, Spina Gleditsiae has detumescence poison holding, the drug effect of evacuation of pus, parasite killing, for the patient of pathogen usually intruding into collateral in protracted disease, considers that to add Spina Gleditsiae effect better in side.
The invention has the advantages that:
(1) the invention provides a kind of Chinese medicine for acne newly, meet clinical needs.
(2) Chinese drug preparation that treatment is used for acne is become washing liquid by the present invention, and easy to use, patient's no pain, external used medicine has no adverse reaction.
(3) clinical test results shows, compared with matched group, and the Chinese medicine for acne of the present invention, 2 course cure rates are up to 79.89%, and matched group cure rate only has 49.92%, and both have significant difference (p < 0.05); 1 the course for the treatment of total effective rate up to 96.83%, and matched group effective percentage only has 80.23%, and both have significant difference (p < 0.05).
In 151 examples of the wherein healing for the treatment of group, 1 the course for the treatment of healing person 63 example, 2 the course for the treatment of healing person 88 example.According to clinical observation, i.e. visible positive effect after general medication 2 course for the treatment of, pimple disappears, and redness disappears, and it is bright and clean as usual that patient cures rear skin.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Prescription: the leaf 20g that washes the dishes, Flos Trollii 12g, Herba Boenninghauseniae 12g, Cortex Phellodendri 12g, Radix Salviae Miltiorrhizae 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Radix Angelicae Dahuricae 6g, Spica Prunellae 6g, Spina Gleditsiae 6g, Concha Margaritifera 9g, Catharsii molossi 6g.
Preparation method:
A, takes the leaf 20g that washes the dishes, Flos Trollii 12g, Herba Boenninghauseniae 12g, Cortex Phellodendri 12g, Radix Salviae Miltiorrhizae 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Radix Angelicae Dahuricae 6g, Spica Prunellae 6g, Spina Gleditsiae 6g, Concha Margaritifera 9g, Catharsii molossi 6g;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 5 times amount soak by water 2 hours, second time adds injection volume 3 times amount soak by water 1.5 hours, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, and filter, sterilizing, to obtain final product.
Embodiment 2
Prescription:
To wash the dishes 18 parts, leaf, Flos Trollii 14 parts, Herba Boenninghauseniae 10 parts, Cortex Phellodendri 14 parts, Radix Salviae Miltiorrhizae 5 parts, Radix Angelicae Sinensis 14 parts, Fructus Forsythiae 10 parts, the Radix Angelicae Dahuricae 7 parts, Spica Prunellae 5 parts, Spina Gleditsiae 7 parts, Concha Margaritifera 8 parts, Catharsii molossi 7 parts.
Preparation method:
A, takes various raw material according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 4-6 times amount soak by water 1.5-2.5 hour, second time adds injection volume 2-4 times amount soak by water 1-2 hour, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, and filter, sterilizing, to obtain final product.
Embodiment 3
Prescription: 22 parts, the leaf that washes the dishes, Flos Trollii 10 parts, Herba Boenninghauseniae 14 parts, Cortex Phellodendri 10 parts, Radix Salviae Miltiorrhizae 7 parts, Radix Angelicae Sinensis 10 parts, Fructus Forsythiae 14 parts, the Radix Angelicae Dahuricae 5 parts, Spica Prunellae 7 parts, Spina Gleditsiae 5 parts, Concha Margaritifera 10 parts, Catharsii molossi 5 parts.
Preparation method:
A, takes various raw material according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 4-6 times amount soak by water 1.5-2.5 hour, second time adds injection volume 2-4 times amount soak by water 1-2 hour, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, and filter, sterilizing, to obtain final product.
Embodiment 4
Prescription:
To wash the dishes 25 parts, leaf, Flos Trollii 8 parts, Herba Boenninghauseniae 16 parts, Cortex Phellodendri 8 parts, Radix Salviae Miltiorrhizae 9 parts, Radix Angelicae Sinensis 8 parts, Fructus Forsythiae 16 parts, the Radix Angelicae Dahuricae 3 parts, Spica Prunellae 9 parts, Spina Gleditsiae 3 parts, Concha Margaritifera 12 parts, Catharsii molossi 3 parts.
Preparation method is with embodiment 1.
Embodiment 5
Prescription:
To wash the dishes 15 parts, leaf, Flos Trollii 16 parts, Herba Boenninghauseniae 8 parts, Cortex Phellodendri 16 parts, Radix Salviae Miltiorrhizae 3 parts, Radix Angelicae Sinensis 16 parts, Fructus Forsythiae 8 parts, the Radix Angelicae Dahuricae 9 parts, Spica Prunellae 3 parts, Spina Gleditsiae 9 parts, Concha Margaritifera 6 parts, Catharsii molossi 9 parts.
Preparation method is with embodiment 1.
1.1 physical data have carried out clinical pharrnacokinetics test to the preparation of embodiments of the invention l, and result is as follows: this group of physical data is totally 189 examples, and matched group 172 example, is the court outpatient.Wherein treatment group man 78 example, female 111 example; 16 ~ 31 years old age, the most elder of the course of disease 4 years, the shortest person 2 months; Matched group man 69 people, female 103 people, age 15-32 year, the most elder of the course of disease 4 years, the shortest person 2 months.Two groups of no difference of science of statistics.Diseased region: facial area is common, is also found in breast cervical region, and color is red, the visible pus point of atop part.Minority case can feel pruritus and pain.
1.2 diagnostic criterias are with reference to " clinical disease diagnosis is according to curing improvement standard ": be 1. common in adolescence, how to occur in pubarche, are apt to occur in face neck, thoracic dorsal top; 2. erythra is kermesinus pimple, and seborrhea, follicular orifice expand, and severe one has blackhead, pus lump, tuberosity, abscess, pigmentation and paralysed trace.
2. Therapeutic Method
Treatment group: adopt the Chinese medicinal lotion prepared of the embodiment of the present invention, (namely getting this product 100ml warm water to 500ml, mixing) is boiled temperature and is smoked and wash acne spots, each 15 minutes, 2 times on the one.Attention: first should clean affected part by warm water before fumigation and wash method, and then first smoke with medicine juice and wash afterwards.
Matched group is with acne ointment (production of traditional Chinese medicines Zhun Zi B20050043 Guizhou Baihua Pharmaceutical Co., Ltd.).Two groups was all 1 course for the treatment of with 10 days, and 2 courses for the treatment of terminate rear observe the curative effect.
3.1 criterions of therapeutical effect are drafted with reference to " clinical disease diagnosis is according to curing improvement standard ".Cure: deflorescence, noresidue pigment or cicatrix; Take a turn for the better: erythra major part disappears, occasionally have new erythra to occur; Invalid: after medication, erythra is unchanged.
3.2 therapeutic outcome two groups Comparison of therapeutic are in table 1.
Table 1 liang group Comparison of therapeutic
| Group | Number of cases | Cure | Take a turn for the better | Invalid | Cure rate (%) | Total effective rate (%) |
| Treatment group | 189 | 151 | 32 | 5 | 79.89* | 96.83* |
| Matched group | 172 | 85 | 53 | 34 | 49.42 | 80.23 |
Note: two groups are compared, and * P<0.05, difference has statistical significance
Compared with matched group, the Chinese medicine for acne of the present invention, 2 course cure rates are up to 79.89%, and matched group cure rate only has 49.92%, and both have significant difference (p < 0.05); 1 the course for the treatment of total effective rate up to 96.83%, and matched group effective percentage only has 80.23%, and both have significant difference (p < 0.05).
In 151 examples of the wherein healing for the treatment of group, 1 the course for the treatment of healing person 63 example, 2 the course for the treatment of healing person 88 example.According to clinical observation, i.e. visible positive effect after general medication 2 course for the treatment of, pimple disappears, and redness disappears, and it is bright and clean as usual that patient cures rear skin.
Treatment group and matched group patient are showed no untoward reaction.
Claims (7)
1., for a Chinese medicine composition for acne, be made up of the raw material of Chinese medicine medicine of following weight portion:
To wash the dishes leaf 15-25 part, Flos Trollii 8-16 part, Herba Boenninghauseniae 8-16 part, Cortex Phellodendri 8-16 part, Radix Salviae Miltiorrhizae 3-9 part, Radix Angelicae Sinensis 8-16 part, Fructus Forsythiae 8-16 part, Radix Angelicae Dahuricae 3-9 part, Spica Prunellae 3-9 part, Spina Gleditsiae 3-9 part, Concha Margaritifera 6-12 part, Catharsii molossi 3-9 part.
2. the Chinese medicine composition for acne according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine medicine of following weight portion:
To wash the dishes leaf 18-22 part, Flos Trollii 10-14 part, Herba Boenninghauseniae 10-14 part, Cortex Phellodendri 10-14 part, Radix Salviae Miltiorrhizae 5-7 part, Radix Angelicae Sinensis 10-14 part, Fructus Forsythiae 10-14 part, Radix Angelicae Dahuricae 5-7 part, Spica Prunellae 5-7 part, Spina Gleditsiae 5-7 part, Concha Margaritifera 8-10 part, Catharsii molossi 5-7 part.
3. the Chinese medicine composition for acne according to claim 2, is characterized in that, is made up of the raw material of Chinese medicine medicine of following weight portion:
To wash the dishes 20 parts, leaf, Flos Trollii 12 parts, Herba Boenninghauseniae 12 parts, Cortex Phellodendri 12 parts, Radix Salviae Miltiorrhizae 6 parts, Radix Angelicae Sinensis 12 parts, Fructus Forsythiae 12 parts, the Radix Angelicae Dahuricae 6 parts, Spica Prunellae 6 parts, Spina Gleditsiae 6 parts, Concha Margaritifera 9 parts, Catharsii molossi 6 parts.
4. the Chinese medicine composition for acne according to claim 1 or 2 or 3, is characterized in that, the dosage form of this Chinese medicine is external wash liquid.
5. the preparation method of the Chinese medicine composition for acne according to claim 1, is characterized in that, comprise the steps:
A, takes various raw material according to required weight portion;
B, extracts volatile oil by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae vapor distillation, and the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 4-6 times amount soak by water 1.5-2.5 hour, second time adds injection volume 2-4 times amount soak by water 1-2 hour, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step b obtain distillation mixes with the concentrated solution of step c, adds water and is adjusted to 2000ml, and filter, sterilizing, to obtain final product.
6. the preparation method of the Chinese medicine composition for acne according to claim 5, is characterized in that, decocting with water in process first time amount of water in described step c is 5 times of injection volume, decocts 2 hours; Second time amount of water is 3 times of injection volume, decocts 1 hour.
7. the preparation method of the Chinese medicine composition for acne according to claim 5, detailed step is as follows:
A, takes the leaf 20g that washes the dishes, Flos Trollii 12g, Herba Boenninghauseniae 12g, Cortex Phellodendri 12g, Radix Salviae Miltiorrhizae 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Radix Angelicae Dahuricae 6g, Spica Prunellae 6g, Spina Gleditsiae 6g, Concha Margaritifera 9g, Catharsii molossi 6g;
B, extracts volatile oil by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae vapor distillation, and the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 5 times amount soak by water 2 hours, second time adds injection volume 3 times amount soak by water 1.5 hours, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step b obtain distillation mixes with the concentrated solution of step c, adds water and is adjusted to 2000ml, and filter, sterilizing, to obtain final product.
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| CN201310709623.1A CN103638193B (en) | 2013-12-21 | 2013-12-21 | A kind of Chinese medicine for acne and preparation method thereof |
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| CN103638193B true CN103638193B (en) | 2015-12-30 |
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| CN105770339A (en) * | 2016-03-30 | 2016-07-20 | 王银法 | Medicament for treating acnes |
| CN106344690A (en) * | 2016-11-11 | 2017-01-25 | 成都悦伦商贸有限公司 | Method for preparing traditional Chinese medicine composition for treating nodulocystic acne |
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| CN101020031A (en) * | 2007-03-08 | 2007-08-22 | 王俊川 | Acne treating Chinese herbal medicine prepn |
| CN102961692A (en) * | 2012-12-21 | 2013-03-13 | 青岛研博电子有限公司 | Composition for treating acne |
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| CN101020031A (en) * | 2007-03-08 | 2007-08-22 | 王俊川 | Acne treating Chinese herbal medicine prepn |
| CN102961692A (en) * | 2012-12-21 | 2013-03-13 | 青岛研博电子有限公司 | Composition for treating acne |
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