CN103638193A - Traditional Chinese medicine used for acnes and preparation method thereof - Google Patents
Traditional Chinese medicine used for acnes and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicines and specifically relates to a traditional Chinese medicine used for acnes and a preparation method thereof. The traditional Chinese medicine used for the acnes, which is disclosed by the invention, is prepared from the following traditional Chinese medicinal materials in parts by weight: 15-25 parts of solanum verbascifolium, 8-16 parts of trollflower, 8-16 parts of chinarue, 8-16 parts of golden cypress, 3-9 parts of salviae miltiorrhizae, 8-16 parts of Chinese angelica, 8-16 parts of fructus forsythia, 3-9 parts of radix angelicae, 3-9 parts of prunella vulgaris, 3-9 parts of spina gleditsiae, 6-12 parts of nacre mother of pearl and 3-9 parts of dung beetles. The traditional Chinese medicine used for acnes, which is disclosed by the invention, has the effects of clearing away heat, drying dampness, removing toxicity for detumescence, promoting blood circulation and dissipating stasis, and is used for various acnes, quick to become effective, high in cure rate and free from adverse reaction.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for acne and preparation method thereof.
Background technology
Acne claims again " comedo ", " skin sore ", " acne ", is a kind of difficult healing, the dermatosis that sickness rate is very high.Doctor trained in Western medicine thinks that acne is a kind of inertia diseases associated with inflammation of take the hair follicle sebum structure multifactor, pleomorphism erythra is feature, mainly grow in adolescence's face, breast, the more rich position of back sebaceous gland, show as acne, inflammation pimple, pustule, tuberosity, cyst and cicatrix.The cause of disease of acne mainly contains: antibacterial infects, as the infection of corynebacterium acnes; Dyshormonia, as Serum Testosterone Levels improves; Metabolism disorder, as vigorous in fat secretion; Gastroenteropathy etc.The traditional Chinese medical science thinks that this disease is, blood stasis dry by the damp and hot blood skin that stagnates, and drinking and eating irregularly, eats well delicious food savoury, pungent in addition, Chong and Ren channel disorder, lung stomach-fire on containing, disturb women's head-ornaments or because of taste have damp and hot due to.
The method of integrative therapy acne is Drug therapy at present.Doctor trained in Western medicine is mainly used retinoid compounds to the treatment of non-inflammation acne, as dimension A emulsifiable paste, or adopts antiandrogen class medicine, as spironolactone etc.; To the treatment of struvite acne, mainly adopt antibiotic as erythromycin, spiramycin etc.The medicine that the traditional Chinese medical science adopts is mainly the oral medicines such as heat-clearing and toxic substances removing, hard masses softening and resolving class decoction, pill, powder.
In existing, the subject matter that exists of western medical treatment method is:
1. cure rate is lower.There is certain effect during medication often, after drug withdrawal, occur repeatedly.
2. there is certain side effect.After some patients were medication, there is untoward reaction, as weak in menoxenia, limbs etc.
3. the course for the treatment of is longer.Be generally 3-6 month.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of Chinese medicine for acne and preparation method thereof.
The present invention realizes by following technical scheme:
For a Chinese medicine for acne, by the raw material of Chinese medicine medicine of following weight portion, made: the leaf 15-25 part of washing the dishes, Flos Trollii 8-16 part, Herba Boenninghauseniae 8-16 part, Cortex Phellodendri 8-16 part, Radix Salviae Miltiorrhizae 3-9 part, Radix Angelicae Sinensis 8-16 part, Fructus Forsythiae 8-16 part, Radix Angelicae Dahuricae 3-9 part, Spica Prunellae 3-9 part, Spina Gleditsiae 3-9 part, Concha Margaritifera 6-12 part, Catharsii molossi 3-9 part.
Preferably, the above-mentioned Chinese medicine for acne, is made by the raw material of Chinese medicine medicine of following weight portion: the leaf 18-22 part of washing the dishes, Flos Trollii 10-14 part, Herba Boenninghauseniae 10-14 part, Cortex Phellodendri 10-14 part, Radix Salviae Miltiorrhizae 5-7 part, Radix Angelicae Sinensis 10-14 part, Fructus Forsythiae 10-14 part, Radix Angelicae Dahuricae 5-7 part, Spica Prunellae 5-7 part, Spina Gleditsiae 5-7 part, Concha Margaritifera 8-10 part, Catharsii molossi 5-7 part.
Preferred, the above-mentioned Chinese medicine for acne, is made by the raw material of Chinese medicine medicine of following weight portion: 20 parts, the leaf that washes the dishes, 12 parts of Flos Trolliis, 12 parts of Herba Boenninghauseniaes, 12 parts of Cortex Phellodendris, 6 parts of Radix Salviae Miltiorrhizaes, 12 parts of Radix Angelicae Sinensis, 12 parts of Fructus Forsythiaes, 6 parts of the Radixs Angelicae Dahuricae, 6 parts of Spica Prunellaes, 6 parts of Spina Gleditsiaes, 9 parts of Concha Margaritiferas, 6 parts of Catharsii molossis.
The above-mentioned Chinese medicine for acne, the dosage form of this Chinese medicine is external wash liquid.
The above-mentioned Chinese medicine external washing liquid preparation method for acne, comprises the steps:
A, takes various raw materials according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time injection volume 4-6 times of water gaging and decoct 1.5-2.5 hour, add for the second time injection volume 2-4 times of water gaging and decoct 1-2 hour, collecting decoction, filters; It is 1.21～1.24 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 80% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, obtains concentrated solution, standby;
D, the aqueous solution that step a makes after distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, filters, and sterilizing, obtains.
Preferably, the above-mentioned Chinese medicine external washing liquid preparation method for acne, in described step c, to decoct with water in process amount of water be for the first time injection volume 5 times, decoct 2 hours; Amount of water is injection volume 3 times for the second time, decocts 1 hour.
The above-mentioned Chinese medicine external washing liquid preparation method for acne, detailed step is as follows:
A, takes the leaf 20g that washes the dishes, Flos Trollii 12g, Herba Boenninghauseniae 12g, Cortex Phellodendri 12g, Radix Salviae Miltiorrhizae 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Radix Angelicae Dahuricae 6g, Spica Prunellae 6g, Spina Gleditsiae 6g, Concha Margaritifera 9g, Catharsii molossi 6g;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, adding for the first time 5 times of water gagings of injection volume decocts 2 hours, adding for the second time 3 times of water gagings of injection volume decocts 1.5 hours, collecting decoction, filters; It is 1.21～1.24 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 80% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, obtains concentrated solution, standby;
D, the aqueous solution that step a makes after distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, filters, and sterilizing, obtains.
The leaf that washes the dishes is Solanaceae nightshade Radix solani coagulantis tree Solanum verbascifolium L., with root and leaf, is used as medicine.Return liver, stomach warp, kidney, spleen, lung, urinary bladder channel.There is heat-clearing and toxic substances removing, the effect of wind-expelling pain-stopping.The clinical accumulation of heat stagnation of QI, the epigastric pain of being used for; Rheumatic arthralgia, treating swelling and pain by traumatic injury.
Flos Trollii has another name called Flos Trollii, another name: non-irrigated lotus, the cold lotus of Herba Tropaeoli, land lotus, nonirrigated farmland lotus, globe-flower, golden pimple are the herb heat-clearing and toxic substances removing that ranunculaceae plant Flos Trollii Trollius chinensis Bunge is.The clinical upper respiratory tract infection that is usually used in, tonsillitis, pharyngitis, acute otitis media, acute myringitis, acute conjunctivitis, acute lymphangitis, aphtha, furuncle.
Herba Boenninghauseniae another name winged steed, sheep do not eat, nine N of two Herba Saxifragae, sheep are had a strong smell grass, copper foot Herba Achilleae, Kochia scoparia (, be the herb of Rutaceae pine wind grass platymiscium Herba Boenninghauseniae Boenninghausenia sessilicarpa Levl..Extract herb autumn, clean cutting is dried.Bitter, pungent, cool.Slightly poisonous.There is heat-clearing and toxic substances removing, the effect of promoting blood circulation and stopping pain.The clinical flu that is usually used in, tonsillitis, parotitis, bronchitis, stomachache abdominal distention, thromboangiitis obliterans, lumbago, traumatic injury.
Catharsii molossi is the dry Scorpio of coleoptera Scarabaeidae insecticide Catharsii molossi Catharsius molossus L..Salty, cold.Nontoxic.There is removing toxic substances, detumescence, the effect of relieving constipation.The clinical sore swollen toxin that is used for, anal fistula, constipation.
Other Cortex Phellodendri, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae, Concha Margaritifera are 2010 editions medical materials that record of Chinese Pharmacopoeia.
The usage and dosage of lotion of medication of the present invention is: with the lotion of medication of the present invention (get this product 100ml and add warm water to 500ml, mix) of 20% concentration, boil temperature and smoke and wash acne position; 2-3 time on the one 10 days is a course for the treatment of.
Chinese medicine for acne of the present invention, has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, and the effect of promoting blood circulation to remove blood stasis, for various types of acnes.
Chinese medicine for acne of the present invention, compatibility is reasonable, and prescription is precise and appropriate.Full side has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, the effect of blood circulation promoting and blood stasis dispelling, in side, wash the dishes leaf, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Spina Gleditsiae, Concha Margaritifera heat-clearing and toxic substances removing, dampness detumescence; Radix Salviae Miltiorrhizae removing heat from blood and promoting blood circulation, Radix Angelicae Sinensis, Catharsii molossi promoting blood circulation to remove obstruction in the collateral.Take a broad view of full side, medication is precise and appropriate, and compatibility is rigorous, and all medicines share, the pathogenesis that hits, the effect of playing altogether heat clearing and damp drying, promoting blood circulation to remove blood stasis, removing toxic substances and promoting subsidence of swelling.For various types of acnes, to treating the acne of various degree, eliminate corresponding symptom and there is good result.In addition, Spina Gleditsiae has detumescence poison holding, and the drug effect of evacuation of pus, parasite killing, for the patient of pathogen usually intruding into collateral in protracted disease, is considered and added Spina Gleditsiae effect better in side.
The invention has the advantages that:
(1) the invention provides a kind of new Chinese medicine for acne, met clinical needs.
(2) Chinese drug preparation that the present invention is used for acne by treatment becomes washing liquid, easy to use, patient's no pain, and external used medicine has no adverse reaction.
(3) clinical test results shows, compares with matched group, the Chinese medicine for acne of the present invention, and 2 course cure rates are up to 79.89%, and matched group cure rate only has 49.92%, both have significant difference (p < 0.05); 1 the course for the treatment of total effective rate up to 96.83%, and matched group effective percentage only has 80.23%, both have significant difference (p < 0.05).
Wherein in 151 examples of the healing for the treatment of group, 1 the course for the treatment of healing person's 63 examples, 2 the course for the treatment of healing person's 88 examples.According to clinical observation, general medication is visible positive effect after 2 courses for the treatment of, and pimple disappears, and redness disappears, and it is bright and clean as usual that patient cures rear skin.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Prescription: the leaf 20g that washes the dishes, Flos Trollii 12g, Herba Boenninghauseniae 12g, Cortex Phellodendri 12g, Radix Salviae Miltiorrhizae 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Radix Angelicae Dahuricae 6g, Spica Prunellae 6g, Spina Gleditsiae 6g, Concha Margaritifera 9g, Catharsii molossi 6g.
Preparation method:
A, takes the leaf 20g that washes the dishes, Flos Trollii 12g, Herba Boenninghauseniae 12g, Cortex Phellodendri 12g, Radix Salviae Miltiorrhizae 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Radix Angelicae Dahuricae 6g, Spica Prunellae 6g, Spina Gleditsiae 6g, Concha Margaritifera 9g, Catharsii molossi 6g;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, adding for the first time 5 times of water gagings of injection volume decocts 2 hours, adding for the second time 3 times of water gagings of injection volume decocts 1.5 hours, collecting decoction, filters; It is 1.21～1.24 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 80% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, obtains concentrated solution, standby;
D, the aqueous solution that step a makes after distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, filters, and sterilizing, obtains.
Embodiment 2
Prescription:
Wash the dishes 18 parts, leaf, 14 parts of Flos Trolliis, 10 parts of Herba Boenninghauseniaes, 14 parts of Cortex Phellodendris, 5 parts of Radix Salviae Miltiorrhizaes, 14 parts of Radix Angelicae Sinensis, 10 parts of Fructus Forsythiaes, 7 parts of the Radixs Angelicae Dahuricae, 5 parts of Spica Prunellaes, 7 parts of Spina Gleditsiaes, 8 parts of Concha Margaritiferas, 7 parts of Catharsii molossis.
Preparation method:
A, takes various raw materials according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time injection volume 4-6 times of water gaging and decoct 1.5-2.5 hour, add for the second time injection volume 2-4 times of water gaging and decoct 1-2 hour, collecting decoction, filters; It is 1.21～1.24 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 80% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, obtains concentrated solution, standby;
D, the aqueous solution that step a makes after distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, filters, and sterilizing, obtains.
Embodiment 3
Prescription: 22 parts, the leaf that washes the dishes, 10 parts of Flos Trolliis, 14 parts of Herba Boenninghauseniaes, 10 parts of Cortex Phellodendris, 7 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Angelicae Sinensis, 14 parts of Fructus Forsythiaes, 5 parts of the Radixs Angelicae Dahuricae, 7 parts of Spica Prunellaes, 5 parts of Spina Gleditsiaes, 10 parts of Concha Margaritiferas, 5 parts of Catharsii molossis.
Preparation method:
A, takes various raw materials according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time injection volume 4-6 times of water gaging and decoct 1.5-2.5 hour, add for the second time injection volume 2-4 times of water gaging and decoct 1-2 hour, collecting decoction, filters; It is 1.21～1.24 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 80% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, obtains concentrated solution, standby;
D, the aqueous solution that step a makes after distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, filters, and sterilizing, obtains.
Embodiment 4
Prescription:
Wash the dishes 25 parts, leaf, 8 parts of Flos Trolliis, 16 parts of Herba Boenninghauseniaes, 8 parts of Cortex Phellodendris, 9 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Angelicae Sinensis, 16 parts of Fructus Forsythiaes, 3 parts of the Radixs Angelicae Dahuricae, 9 parts of Spica Prunellaes, 3 parts of Spina Gleditsiaes, 12 parts of Concha Margaritiferas, 3 parts of Catharsii molossis.
Preparation method is with embodiment 1.
Embodiment 5
Prescription:
Wash the dishes 15 parts, leaf, 16 parts of Flos Trolliis, 8 parts of Herba Boenninghauseniaes, 16 parts of Cortex Phellodendris, 3 parts of Radix Salviae Miltiorrhizaes, 16 parts of Radix Angelicae Sinensis, 8 parts of Fructus Forsythiaes, 9 parts of the Radixs Angelicae Dahuricae, 3 parts of Spica Prunellaes, 9 parts of Spina Gleditsiaes, 6 parts of Concha Margaritiferas, 9 parts of Catharsii molossis.
Preparation method is with embodiment 1.
1.1 physical data have been carried out clinical pharmacodynamics test to the preparation of embodiments of the invention l, and result is as follows: this group of physical data is totally 189 examples, and matched group 172 examples, are the outpatient of the court.Treatment group man 78 examples wherein, female's 111 examples; 16 ~ 31 years old age, the elder of the course of disease 4 years, the shortest person 2 months; Matched group man 69 people, female 103 people, age 15-32 year, the elder of the course of disease 4 years, the shortest person 2 months.Two groups of no difference of science of statistics.Diseased region: facial area is common, is also found in breast cervical region, and color is red, the visible pus point in part top.Minority case can be felt pruritus and pain.
1.2 diagnostic criterias with reference to < < clinical disease diagnosis according to curing improvement standard > >: be 1. common in adolescence, how in pubarche, to occur, be apt to occur in face neck, thoracic dorsal top; 2. erythra is kermesinus pimple, and seborrhea, follicular orifice expand, and severe one has blackhead, pus lump, tuberosity, abscess, pigmentation and paralysed trace.
2. Therapeutic Method
Treatment group: the Chinese medicinal lotion that adopt to adopt the embodiment of the present invention to prepare, (get this product 100ml and add warm water to 500ml, mix) boiled temperature and smoked and wash acne position, and each 15 minutes, 2 times on the one.Attention: should first clean affected part by warm water before fumigation and wash method, and then first smoke afterwards and wash with medicine juice.
Acne ointment for matched group (production of traditional Chinese medicines Zhun Zi B20050043 Guizhou Baihua Pharmaceutical Co., Ltd.).All take 10 days as 1 course for the treatment of, finish rear observe the curative effect 2 courses for the treatment of for two groups.
3.1 criterions of therapeutical effect are drafted according to curing improvement standard > > with reference to < < clinical disease diagnosis.Cure: deflorescence, noresidue pigment or cicatrix; Take a turn for the better: erythra major part disappears, occasionally have new erythra to occur; Invalid: after medication, erythra is unchanged.
3.2 two groups of therapeutic outcomes Comparison of therapeutic are in Table 1.
Table 1 liang group Comparison of therapeutic
| Group | Number of cases | Cure | Take a turn for the better | Invalid | Cure rate (%) | Total effective rate (%) |
| Treatment group | 189 | 151 | 32 | 5 | 79.89* | 96.83* |
| Matched group | 172 | 85 | 53 | 34 | 49.42 | 80.23 |
Note: two groups of comparisons, * P<0.05, difference has statistical significance
Compare with matched group, the Chinese medicine for acne of the present invention, 2 course cure rates are up to 79.89%, and matched group cure rate only has 49.92%, both have significant difference (p < 0.05); 1 the course for the treatment of total effective rate up to 96.83%, and matched group effective percentage only has 80.23%, both have significant difference (p < 0.05).
Wherein in 151 examples of the healing for the treatment of group, 1 the course for the treatment of healing person's 63 examples, 2 the course for the treatment of healing person's 88 examples.According to clinical observation, general medication is visible positive effect after 2 courses for the treatment of, and pimple disappears, and redness disappears, and it is bright and clean as usual that patient cures rear skin.
Treatment group and matched group patient are showed no untoward reaction.
Claims (7)
1. for a Chinese medicine for acne, by the raw material of Chinese medicine medicine of following weight portion, made:
Wash the dishes leaf 15-25 part, Flos Trollii 8-16 part, Herba Boenninghauseniae 8-16 part, Cortex Phellodendri 8-16 part, Radix Salviae Miltiorrhizae 3-9 part, Radix Angelicae Sinensis 8-16 part, Fructus Forsythiae 8-16 part, Radix Angelicae Dahuricae 3-9 part, Spica Prunellae 3-9 part, Spina Gleditsiae 3-9 part, Concha Margaritifera 6-12 part, Catharsii molossi 3-9 part.
2. the Chinese medicine for acne according to claim 1, is characterized in that, by the raw material of Chinese medicine medicine of following weight portion, is made:
Wash the dishes leaf 18-22 part, Flos Trollii 10-14 part, Herba Boenninghauseniae 10-14 part, Cortex Phellodendri 10-14 part, Radix Salviae Miltiorrhizae 5-7 part, Radix Angelicae Sinensis 10-14 part, Fructus Forsythiae 10-14 part, Radix Angelicae Dahuricae 5-7 part, Spica Prunellae 5-7 part, Spina Gleditsiae 5-7 part, Concha Margaritifera 8-10 part, Catharsii molossi 5-7 part.
3. the Chinese medicine for acne according to claim 2, is characterized in that, by the raw material of Chinese medicine medicine of following weight portion, is made:
Wash the dishes 20 parts, leaf, 12 parts of Flos Trolliis, 12 parts of Herba Boenninghauseniaes, 12 parts of Cortex Phellodendris, 6 parts of Radix Salviae Miltiorrhizaes, 12 parts of Radix Angelicae Sinensis, 12 parts of Fructus Forsythiaes, 6 parts of the Radixs Angelicae Dahuricae, 6 parts of Spica Prunellaes, 6 parts of Spina Gleditsiaes, 9 parts of Concha Margaritiferas, 6 parts of Catharsii molossis.
4. the Chinese medicine for acne according to claim 4, is characterized in that, the dosage form of this Chinese medicine is external wash liquid.
5. the Chinese medicine external washing liquid preparation method for acne claimed in claim 1, comprises the steps:
A, takes various raw materials according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time injection volume 4-6 times of water gaging and decoct 1.5-2.5 hour, add for the second time injection volume 2-4 times of water gaging and decoct 1-2 hour, collecting decoction, filters; It is 1.21～1.24 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 80% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, obtains concentrated solution, standby;
D, the aqueous solution that step a makes after distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, filters, and sterilizing, obtains.
6. the Chinese medicine external washing liquid preparation method for acne according to claim 6, is characterized in that, in described step c, to decoct with water in process amount of water be for the first time injection volume 5 times, decoct 2 hours; Amount of water is injection volume 3 times for the second time, decocts 1 hour.
7. the Chinese medicine external washing liquid preparation method for acne according to claim 5, detailed step is as follows:
A, takes the leaf 20g that washes the dishes, Flos Trollii 12g, Herba Boenninghauseniae 12g, Cortex Phellodendri 12g, Radix Salviae Miltiorrhizae 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Radix Angelicae Dahuricae 6g, Spica Prunellae 6g, Spina Gleditsiae 6g, Concha Margaritifera 9g, Catharsii molossi 6g;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, the Radix Angelicae Dahuricae, Spica Prunellae, Spina Gleditsiae water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Flos Trollii, Herba Boenninghauseniae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Concha Margaritifera, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, adding for the first time 5 times of water gagings of injection volume decocts 2 hours, adding for the second time 3 times of water gagings of injection volume decocts 1.5 hours, collecting decoction, filters; It is 1.21～1.24 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 80% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, obtains concentrated solution, standby;
D, the aqueous solution that step a makes after distillation mixes with the concentrated solution of step b, adds water and is adjusted to 2000ml, filters, and sterilizing, obtains.
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| CN201310709623.1A CN103638193B (en) | 2013-12-21 | 2013-12-21 | A kind of Chinese medicine for acne and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105770339A (en) * | 2016-03-30 | 2016-07-20 | 王银法 | Medicament for treating acnes |
| CN106344690A (en) * | 2016-11-11 | 2017-01-25 | 成都悦伦商贸有限公司 | Method for preparing traditional Chinese medicine composition for treating nodulocystic acne |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101020031A (en) * | 2007-03-08 | 2007-08-22 | 王俊川 | Acne treating Chinese herbal medicine prepn |
| CN102961692A (en) * | 2012-12-21 | 2013-03-13 | 青岛研博电子有限公司 | Composition for treating acne |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101020031A (en) * | 2007-03-08 | 2007-08-22 | 王俊川 | Acne treating Chinese herbal medicine prepn |
| CN102961692A (en) * | 2012-12-21 | 2013-03-13 | 青岛研博电子有限公司 | Composition for treating acne |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105770339A (en) * | 2016-03-30 | 2016-07-20 | 王银法 | Medicament for treating acnes |
| CN106344690A (en) * | 2016-11-11 | 2017-01-25 | 成都悦伦商贸有限公司 | Method for preparing traditional Chinese medicine composition for treating nodulocystic acne |
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