CN103599263B - A kind of Chinese medicine for hemorrhoid and preparation method thereof - Google Patents
A kind of Chinese medicine for hemorrhoid and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for hemorrhoid and preparation method thereof.Chinese medicine for hemorrhoid of the present invention, is made up of the raw material of Chinese medicine medicine of following weight portion: Flos Paulowniae 24-36 part, Radix Sanguisorbae 3-9 part, Herba Diclipterae Chinensis 8-16 part, Herba Violae 8-16 part, Herba Taraxaci 8-16 part, Radix Angelicae Sinensis 8-16 part, Natrii Sulfas 3-9 part, Alumen 3-9 part, Herb Polygoni Chinensis 8-16 part, Flos Sophorae 8-16 part, Flos Lonicerae 8-16 part, Pericarpium Zanthoxyli 8-16 part, Herba Artemisiae Scopariae 8-16 part, Folium Artemisiae Argyi 8-16 part.Chinese medicine for hemorrhoid of the present invention, has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, effect of cooling blood for hemostasis, and clinical test results shows, its total effective rate is up to 96.49%.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for hemorrhoid and preparation method thereof.
Background technology
Hemorrhoid are ancient names of disease, can trace back to Qin Han dynasty to the understanding of hemorrhoid." hemorrhoid " develop from " temple ", just have the record about " temple " in " sufficient arm 11 arteries and veins moxibustion warp "." Plain Questions vital QI of the body connecting with natural QI opinion " carries: " be thus satiated with food, flaccidity of muscles and vessels, intestinal trip is hemorrhoid." explicitly pointed out hemorrhoid formation relevant with eating and drinking without temperance, and point out that the pathology of hemorrhoid is " flaccidity of muscles and vessels ", namely venation blood vessel is indulged relaxation and is not received." Compendium of medicine " describes hemorrhoid for " to give prominence to as hemorrhoid as there being hill in large pool; In people's nine orifices, allly there are hemorrhoid of little meat outstanding all days ".Hemorrhoid are the common disease of anorectum department, doctor trained in Western medicine is a lot of about the therapeutic modality of hemorrhoid, but be mostly to eliminate for the purpose of symptom, " flaccidity of muscles and vessels " this pathology can not be eliminated, therefore most hemorrhoid need operative treatment, but postoperative most patient pain is unbearably, particularly change dressings or first defecation time pain more severe.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of Chinese medicine for hemorrhoid and preparation method thereof.
The present invention is realized by following technical scheme:
For a Chinese medicine for hemorrhoid, be made up of the raw material of Chinese medicine medicine of following weight portion:
Flos Paulowniae 24-36 part, Radix Sanguisorbae 3-9 part, Herba Diclipterae Chinensis 8-16 part, Herba Violae 8-16 part, Herba Taraxaci 8-16 part, Radix Angelicae Sinensis 8-16 part, Natrii Sulfas 3-9 part, Alumen 3-9 part, Herb Polygoni Chinensis 8-16 part, Flos Sophorae 8-16 part, Flos Lonicerae 8-16 part, Pericarpium Zanthoxyli 8-16 part, Herba Artemisiae Scopariae 8-16 part, Folium Artemisiae Argyi 8-16 part.
Preferably, the above-mentioned Chinese medicine for hemorrhoid, be made up of the raw material of Chinese medicine medicine of following weight portion:
Flos Paulowniae 28-32 part, Radix Sanguisorbae 5-7 part, Herba Diclipterae Chinensis 10-14 part, Herba Violae 10-14 part, Herba Taraxaci 10-14 part, Radix Angelicae Sinensis 10-14 part, Natrii Sulfas 5-7 part, Alumen 5-7 part, Herb Polygoni Chinensis 10-14 part, Flos Sophorae 10-14 part, Flos Lonicerae 10-14 part, Pericarpium Zanthoxyli 10-14 part, Herba Artemisiae Scopariae 10-14 part, Folium Artemisiae Argyi 10-14 part.
Preferred, the above-mentioned Chinese medicine for hemorrhoid, be made up of the raw material of Chinese medicine medicine of following weight portion:
Flos Paulowniae 30 parts, Radix Sanguisorbae 6 parts, Herba Diclipterae Chinensis 12 parts, Herba Violae 12 parts, Herba Taraxaci 12 parts, Radix Angelicae Sinensis 12 parts, 6 parts, Natrii Sulfas, Alumen 6 parts, Herb Polygoni Chinensis 12 parts, 12 parts, Flos Sophorae, Flos Lonicerae 12 parts, 12 parts, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae 12 parts, Folium Artemisiae Argyi 12 parts.
The upper described Chinese medicine for hemorrhoid, the dosage form of this Chinese medicine is oral formulations.
Preferably, the above-mentioned Chinese medicine for hemorrhoid, the dosage form of this Chinese medicine is external wash liquid.
The upper described Chinese medicine external washing liquid preparation method for hemorrhoid, comprises the steps:
A, takes various raw material according to required weight portion;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 5-7 times amount soak by water 1-2 hour, second time adds injection volume 3-5 times amount soak by water 0.5-1.5 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.23 ~ 1.26, lets cool, and adds ethanol and reaches 75% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, and add the water dilution of equivalent, stir evenly, 2 ~ 5 DEG C leave standstill cold preservation 24 hours again, filter, obtain filtrate;
Aqueous solution after d, step a obtain distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000 parts, filter, sterilizing, to obtain final product.
Preferably, above-mentioned in the Chinese medicine external washing liquid preparation method of hemorrhoid, decocting with water first time in process amount of water in described step c is 6 times of injection volume, decocts 1.5 hours; Second time amount of water is 4 times of injection volume, decocts 1 hour.
The above-mentioned Chinese medicine external washing liquid preparation method for hemorrhoid, detailed step is as follows:
A, takes Flos Paulowniae 30g, Radix Sanguisorbae 6g, Herba Diclipterae Chinensis 12g, Herba Violae 12g, Herba Taraxaci 12g, Radix Angelicae Sinensis 12g, Natrii Sulfas 6g, Alumen 6g, Herb Polygoni Chinensis 12g, Flos Sophorae 12g, Flos Lonicerae 12g, Pericarpium Zanthoxyli 12g, Herba Artemisiae Scopariae 12g, Folium Artemisiae Argyi 12g raw material;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 6 times amount soak by water 1.5 hours, second time adds injection volume 4 times amount soak by water 1 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.23 ~ 1.26, lets cool, and adds ethanol and reaches 75% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, and add the water dilution of equivalent, stir evenly, 2 ~ 5 DEG C leave standstill cold preservation 24 hours again, filter, obtain filtrate;
Aqueous solution after d, step a obtain distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, to obtain final product.
It is of the present invention in the Chinese medicine ingredients raw material of hemorrhoid,
Flos Paulowniae is the flower of dicotyledon medicine goatweed Paulownia Paulownia fortunei (Seem.) Hemsl. or royal paulownia P. Tomentosa (Thunb.) Steud..Bitter, pungent, put down into lung meridian.Wind-dispelling heat-dissipating, heat-clearing and toxic substances removing, liver heat removing and eyesight improving.Be usually used in treatment and control upper respiratory tract infection, bronchopneumonia, acute tonsillitis, bacillary dysentery, acute enteritis, acute conjunctivitis, parotitis, furuncle and phyma.
Herba Diclipterae Chinensis has another name called Herba Strobilanthis tetraspermi, Huang Suede grass, is the herb of dicotyledon medicine acanthaceous plant Herba Strobilanthis tetraspermi Strobilanthes tetraspermus (Champ. Ex Benth.) Druce.There is heat-clearing and toxic substances removing, removing heat from blood, promote the production of body fluid, effect of diuresis; With control in excess-heat tie maculopapulae due to toxic heat, have blood in stool, the disease such as dysuria, toxic swelling furuncle; External can with controlling traumatic injury, red and swollen hemorrhage.
Herb Polygoni Chinensis has another name called meal rattan, Linesless charcoal rattan, Herba Polygoni cymosi, river seven, the careless herb for Polygonaceae arsesmart Herb Polygoni Chinensis Polygunum chinense L. of plain rice clearly.The four seasons can adopt, and clean and dry or using fresh herb.Have heat-clearing and toxic substances removing, dampness removing disappears stagnant, blood-cooling itch-relieving, effect of improving acuity of vision and removing nebula.Clinically be used for dysentery, enteritis, dyspepsia, hepatitis, flu, tonsillitis, pharyngolaryngitis, diphtheria, pertussis, corneal nebula, colpitis mycotica, leucorrhea, mastitis, furuncle and phyma, children's's impetigo, eczema, venom.
Other Radix Sanguisorbae, Herba Violae, Herba Taraxaci, Radix Angelicae Sinensis, Natrii Sulfas, Alumen, Flos Sophorae, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, the equal Chinese Pharmacopoeia of Folium Artemisiae Argyi 2010 editions medical materials recorded.
The usage and dosage of lotion of medication of the present invention is: boil temperature with the lotion of medication of the present invention of 20% concentration (namely getting this product 100ml warm water to 500ml, mixing) and smoke and wash anus position; Or with irrigator, the lotion of medication of the present invention of 10% concentration is delivered to deep rectum flushing anus.2-3 time on the one 7 days is a course for the treatment of.
Chinese medicine for hemorrhoid of the present invention, has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, effect of cooling blood for hemostasis, for various types of hemorrhoid.
Chinese medicine fumigation and washing is one of important external treatment of traditional Chinese medical science anorectal surgical, it is the traditional method for the treatment of hemorrhoid, fumigation and wash method refers to borrows the medicine vapour of transpiration to smoke affected part, again by affected part demibain in medicinal liquid, its efficacy of a drug and heating power is relied on to directly act on pathological change of anorectal position, make this place's space between skin and muscles dredging, QI and blood is smooth, thus reaches heat clearing and damp drying, promoting blood circulation and detumescence, analgesic hemostatic, convergence itching-relieving efficacies.Have special effect to treatment skin infection, day has no side effect.
Chinese medicine is thought, the generation of hemorrhoid disease is mostly by eating and drinking without temperance, rheumatism downward attack by pathogenic heat large intestine, and pyretic toxicity pents up, heat in blood dryness of the intestine, and poly-not the faling apart of knot forms.Chinese medicine for hemorrhoid of the present invention, compatibility is reasonable, and prescription is precise and appropriate.Full side has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, effect of cooling blood for hemostasis, Flos Paulowniae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Flos Lonicerae, Herba Artemisiae Scopariae heat-clearing and toxic substances removing in side, dampness is subsided a swelling, purging heat to relax the bowels, removing toxicity for eliminating carbuncles, clots absorbing stimulates the menstrual flow, removing damp-heat, cooling blood for hemostasis; Natrii Sulfas purges heat, and moisturizes, softening the hard mass; External can control all kinds of skin infection carbuncle, has blood in stool; Flos Sophorae cooling blood for hemostasis; Radix Angelicae Sinensis promoting blood circulation to remove obstruction in the collateral, eliminating stasis to stop pain; Alumen convergence is astringent or styptic treatment for spontaneous sweating; Pericarpium Zanthoxyli, Folium Artemisiae Argyi, Radix Angelicae Pubescentis dispel cold-damp.Take a broad view of full side, medication is precise and appropriate, and compatibility is rigorous, and all medicines share, and hit pathogenesis, plays effect of heat clearing and damp drying, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain altogether.For various types of hemorrhoid, with the passing of time it be applicable to the course of disease, the patient of recurrent exerbation, and curative effect is better more outstanding.
The invention has the advantages that:
(1) the invention provides a kind of Chinese medicine for hemorrhoid newly, meet clinical needs.
(2) Chinese drug preparation that treatment is used for hemorrhoid is become washing liquid by the present invention, and easy to use, patient's no pain, avoids pain and the post-operative complication of operation.
(3) clinical test results shows, compared with matched group, and the Chinese medicine for hemorrhoid of the present invention, cure rate is up to 68.42%, and matched group cure rate only has 23.21%, and both have significant difference (p < 0.01); Total effective rate is up to 96.49%, and matched group effective percentage only has both 48.28% and has significant difference (p < 0.01).
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Prescription: Flos Paulowniae 30g, Radix Sanguisorbae 6g, Herba Diclipterae Chinensis 12g, Herba Violae 12g, Herba Taraxaci 12g, Radix Angelicae Sinensis 12g, Natrii Sulfas 6g, Alumen 6g, Herb Polygoni Chinensis 12g, Flos Sophorae 12g, Flos Lonicerae 12g, Pericarpium Zanthoxyli 12g, Herba Artemisiae Scopariae 12g, Folium Artemisiae Argyi 12g.
Preparation method:
A, takes Flos Paulowniae 30g, Radix Sanguisorbae 6g, Herba Diclipterae Chinensis 12g, Herba Violae 12g, Herba Taraxaci 12g, Radix Angelicae Sinensis 12g, Natrii Sulfas 6g, Alumen 6g, Herb Polygoni Chinensis 12g, Flos Sophorae 12g, Flos Lonicerae 12g, Pericarpium Zanthoxyli 12g, Herba Artemisiae Scopariae 12g, Folium Artemisiae Argyi 12g;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 6 times amount soak by water 1.5 hours, second time adds injection volume 4 times amount soak by water 1 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.23 ~ 1.26, lets cool, and adds ethanol and reaches 75% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, and add the water dilution of equivalent, stir evenly, 2 ~ 5 DEG C leave standstill cold preservation 24 hours again, filter, obtain filtrate;
Aqueous solution after d, step a obtain distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, to obtain final product.
Embodiment 2
Prescription: Flos Paulowniae 28g, Radix Sanguisorbae 7g, Herba Diclipterae Chinensis 10g, Herba Violae 14g, Herba Taraxaci 10g, Radix Angelicae Sinensis 14g, Natrii Sulfas 5g, Alumen 7g, Herb Polygoni Chinensis 10g, Flos Sophorae 14g, Flos Lonicerae 10g, Pericarpium Zanthoxyli 14g, Herba Artemisiae Scopariae 10g, Folium Artemisiae Argyi 14g.
Preparation method:
A, takes Flos Paulowniae 28g, Radix Sanguisorbae 7g, Herba Diclipterae Chinensis 10g, Herba Violae 14g, Herba Taraxaci 10g, Radix Angelicae Sinensis 14g, Natrii Sulfas 5g, Alumen 7g, Herb Polygoni Chinensis 10g, Flos Sophorae 14g, Flos Lonicerae 10g, Pericarpium Zanthoxyli 14g, Herba Artemisiae Scopariae 10g, Folium Artemisiae Argyi 14g;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 7 times amount soak by water 2 hours, second time adds injection volume 3 times amount soak by water 0.5 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.23 ~ 1.26, lets cool, and adds ethanol and reaches 75% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, and add the water dilution of equivalent, stir evenly, 2 ~ 5 DEG C leave standstill cold preservation 24 hours again, filter, obtain filtrate;
Aqueous solution after d, step a obtain distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, to obtain final product.
Embodiment 3
Prescription: Flos Paulowniae 32g, Radix Sanguisorbae 5g, Herba Diclipterae Chinensis 14g, Herba Violae 10g, Herba Taraxaci 14g, Radix Angelicae Sinensis 10g, Natrii Sulfas 7g, Alumen 5g, Herb Polygoni Chinensis 14g, Flos Sophorae 10g, Flos Lonicerae 14g, Pericarpium Zanthoxyli 10g, Herba Artemisiae Scopariae 14g, Folium Artemisiae Argyi 10g.
Preparation method:
A, takes Flos Paulowniae 32g, Radix Sanguisorbae 5g, Herba Diclipterae Chinensis 14g, Herba Violae 10g, Herba Taraxaci 14g, Radix Angelicae Sinensis 10g, Natrii Sulfas 7g, Alumen 5g, Herb Polygoni Chinensis 14g, Flos Sophorae 10g, Flos Lonicerae 14g, Pericarpium Zanthoxyli 10g, Herba Artemisiae Scopariae 14g, Folium Artemisiae Argyi 10g;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 5 times amount soak by water 1 hour, second time adds injection volume 5 times amount soak by water 1.5 hours, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.23 ~ 1.26, lets cool, and adds ethanol and reaches 75% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, and add the water dilution of equivalent, stir evenly, 2 ~ 5 DEG C leave standstill cold preservation 24 hours again, filter, obtain filtrate;
Aqueous solution after d, step a obtain distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, to obtain final product.
Embodiment 4
Prescription: Flos Paulowniae 36 parts, Radix Sanguisorbae 3 parts, Herba Diclipterae Chinensis 6 parts, Herba Violae 8 parts, Herba Taraxaci 16 parts, Radix Angelicae Sinensis 8 parts, 9 parts, Natrii Sulfas, Alumen 3 parts, Herb Polygoni Chinensis 16 parts, 8 parts, Flos Sophorae, Flos Lonicerae 16 parts, 8 parts, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae 16 parts, Folium Artemisiae Argyi 8 parts.
Preparation method is with embodiment 1.
Embodiment 5
Prescription: Flos Paulowniae 24g, Radix Sanguisorbae 9g, Herba Diclipterae Chinensis 8g, Herba Violae 16g, Herba Taraxaci 8g, Radix Angelicae Sinensis 16g, Natrii Sulfas 3g, Alumen 9g, Herb Polygoni Chinensis 8g, Flos Sophorae 16g, Flos Lonicerae 8g, Pericarpium Zanthoxyli 16g, Herba Artemisiae Scopariae 8g, Folium Artemisiae Argyi 16g.
Preparation method is with embodiment 1.
Carried out clinical pharrnacokinetics test to the preparation of embodiments of the invention l, result is as follows:
Patient is totally 226 examples, is divided into 2 groups at random.In treatment group 114 example, man 63 example, female 51 example; 16 ~ 68 years old age, 38 years old mean age; The course of disease≤7 day 79 examples, course of disease > 7 days 35 examples.In matched group 112 example, man 62 example, female 50 example; 18 ~ 65 years old age, 37 years old mean age; The course of disease≤7 day 76 examples, course of disease > 7 days 36 examples.The physical data such as two groups of Genders, age, the course of disease, state of an illness compare there was no significant difference (P > O.05), have comparability.
2 Therapeutic Method
2.1 treatment groups: boil temperature with the lotion of medication of the present invention of 20% concentration (namely getting this product 100ml warm water to 500ml, mixing) and smoke and wash anus position, each 15 minutes.Attention: first should clean affected part by warm water before fumigation and wash method, and then first smoke with medicine juice and wash afterwards, medicine soup temperature is placed in water with hands does not scald for degree.
2.2 matched groups: adopt 0.02 % (1:5000) potassium permanganate solution 1500ml, fumigation and wash method demibain; Outer painting erythromycin ointment, every day 1 time.
Two groups equal every day fumigation and wash method 2 times, each 30min continuous 7 days is 1 course for the treatment of.1 course for the treatment of terminates rear judgement curative effect.
3 observation of curative effect
3.1 criterions of therapeutical effect: effective: symptom is obviously improved, anus edge is swollen, thrombosis mass reduction degree > 2/3; Effective: symptom is improved, anus edge edema, thrombosis lump absorb and reach 1/3 ~ 2/3; Invalid: symptom is not improved, anus edge edema, thrombosis mass reduction degree <1/3.
3.2 therapeutic outcomes: in table 1.
A table 1 liang group therapeutic effect compares
| Group | Number of cases | Effective | Effectively | Invalid | Cure rate (%) | Total effective rate (%) |
| Treatment group | 114 | 78 | 32 | 4 | 68.42* | 96.49* |
| Matched group | 112 | 26 | 28 | 57 | 23.21 | 48.28 |
Note: compare in matched group, p < 0.01.
Compared with matched group, the Chinese medicine for hemorrhoid of the present invention, cure rate is up to 68.42%, and matched group cure rate only has 23.21%, and both have significant difference (p < 0.01); Total effective rate is up to 96.49%, and matched group effective percentage only has both 48.28% and has significant difference (p < 0.01).
Claims (5)
1., for a Chinese medicine for hemorrhoid, be made up of the raw material of Chinese medicine medicine of following weight portion:
Flos Paulowniae 24-36 part, Radix Sanguisorbae 3-9 part, Herba Diclipterae Chinensis 8-16 part, Herba Violae 8-16 part, Herba Taraxaci 8-16 part, Radix Angelicae Sinensis 8-16 part, Natrii Sulfas 3-9 part, Alumen 3-9 part, Herb Polygoni Chinensis 8-16 part, Flos Sophorae 8-16 part, Flos Lonicerae 8-16 part, Pericarpium Zanthoxyli 8-16 part, Herba Artemisiae Scopariae 8-16 part, Folium Artemisiae Argyi 8-16 part;
The dosage form of this Chinese medicine is external wash liquid;
The described Chinese medicine external washing liquid preparation method for hemorrhoid, comprises the steps:
A, takes various raw material according to required weight portion;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 5-7 times amount soak by water 1-2 hour, second time adds injection volume 3-5 times amount soak by water 0.5-1.5 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.23 ~ 1.26, lets cool, and adds ethanol and reaches 75% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, and add the water dilution of equivalent, stir evenly, 2 ~ 5 DEG C leave standstill cold preservation 24 hours again, filter, obtain filtrate;
Aqueous solution after d, step b obtain distillation mixes with the filtrate of step c, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000 parts, filter, sterilizing, to obtain final product.
2. the Chinese medicine for hemorrhoid according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine medicine of following weight portion:
Flos Paulowniae 28-32 part, Radix Sanguisorbae 5-7 part, Herba Diclipterae Chinensis 10-14 part, Herba Violae 10-14 part, Herba Taraxaci 10-14 part, Radix Angelicae Sinensis 10-14 part, Natrii Sulfas 5-7 part, Alumen 5-7 part, Herb Polygoni Chinensis 10-14 part, Flos Sophorae 10-14 part, Flos Lonicerae 10-14 part, Pericarpium Zanthoxyli 10-14 part, Herba Artemisiae Scopariae 10-14 part, Folium Artemisiae Argyi 10-14 part.
3. the Chinese medicine for hemorrhoid according to claim 2, is characterized in that, is made up of the raw material of Chinese medicine medicine of following weight portion:
Flos Paulowniae 30 parts, Radix Sanguisorbae 6 parts, Herba Diclipterae Chinensis 12 parts, Herba Violae 12 parts, Herba Taraxaci 12 parts, Radix Angelicae Sinensis 12 parts, 6 parts, Natrii Sulfas, Alumen 6 parts, Herb Polygoni Chinensis 12 parts, 12 parts, Flos Sophorae, Flos Lonicerae 12 parts, 12 parts, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae 12 parts, Folium Artemisiae Argyi 12 parts.
4. the Chinese medicine for hemorrhoid according to claim 1, is characterized in that, decocting with water in process first time amount of water in described step c is 6 times of injection volume, decocts 1.5 hours; Second time amount of water is 4 times of injection volume, decocts 1 hour.
5. the Chinese medicine for hemorrhoid according to claim 1, its preparation method detailed step is as follows:
A, takes Flos Paulowniae 30g, Radix Sanguisorbae 6g, Herba Diclipterae Chinensis 12g, Herba Violae 12g, Herba Taraxaci 12g, Radix Angelicae Sinensis 12g, Natrii Sulfas 6g, Alumen 6g, Herb Polygoni Chinensis 12g, Flos Sophorae 12g, Flos Lonicerae 12g, Pericarpium Zanthoxyli 12g, Herba Artemisiae Scopariae 12g, Folium Artemisiae Argyi 12g raw material;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 6 times amount soak by water 1.5 hours, second time adds injection volume 4 times amount soak by water 1 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.23 ~ 1.26, lets cool, and adds ethanol and reaches 75% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.06 ~ 1.10, and add the water dilution of equivalent, stir evenly, 2 ~ 5 DEG C leave standstill cold preservation 24 hours again, filter, obtain filtrate;
Aqueous solution after d, step b obtain distillation mixes with the filtrate of step c, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, to obtain final product.
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