CN103599263A - Traditional Chinese medicine for haemorrhoids and preparation method thereof - Google Patents
Traditional Chinese medicine for haemorrhoids and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for haemorrhoids and a preparation method thereof. The traditional Chinese medicine for haemorrhoids is prepared from the following medicinal raw materials in parts by weight: 24-36 parts of fortune paulownia flower, 3-9 parts of garden burnet, 8-16 parts of dicliptera chinensis, 8-16 parts of herba violae, 8-16 parts of dandelion, 8-16 parts of Chinese angelica, 3-9 parts of mirabilite, 3-9 parts of alumen, 8-16 parts of Chinese knotweed herb, 8-16 parts of sophora flower, 8-16 parts of honeysuckle, 8-16 parts of pepper, 8-16 parts of oriental wormwood and 8-16 parts of folium artemisiae argyi. The traditional Chinese medicine for haemorrhoids has the effects of clearing away heat, drying dampness, removing toxicity for detumescence, promoting blood circulation to arrest pain and cooling blood for hemostasis. Clinical test results prove that the total effective rate of the traditional Chinese medicine reaches 96.49%.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for hemorrhoid and preparation method thereof.
Background technology
Hemorrhoid are ancient names of disease, to the understanding of hemorrhoid, can trace back to Qin Han period." hemorrhoid " develop from " temple ", as far back as the 11 arteries and veins moxibustions of < < foot arm in > > just relevant for the record at " temple ".< < Plain Questions vital QI of the body connecting with natural QI opinion > > carries: " thereby be satiated with food, flaccidity of muscles and vessels, intestinal trip is hemorrhoid." explicitly pointed out hemorrhoid formation relevant with eating and drinking without temperance, and point out that the pathology of hemorrhoid is " flaccidity of muscles and vessels ", the vertical relaxation of venation blood vessel is not received.< < Compendium of medicine > > describes hemorrhoid for " to give prominence to as hemorrhoid as there being hill in large pool; In people's nine orifices, allly there are outstanding all day hemorrhoid of little meat ".The disease that Zhi Wei anorectal section is common, doctor trained in Western medicine is a lot of about the therapeutic modality of hemorrhoid, but be mostly take to eliminate symptom as object, can not eliminate " flaccidity of muscles and vessels " this pathology, therefore most hemorrhoid need operative treatment, but postoperative most patient's hurt like hell, particularly change dressings or first during defecation pain more severe.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of Chinese medicine for hemorrhoid and preparation method thereof.
The present invention realizes by following technical scheme:
For a Chinese medicine for hemorrhoid, by the raw material of Chinese medicine medicine of following weight portion, made:
Flos Paulowniae 24-36 part, Radix Sanguisorbae 3-9 part, Herba Diclipterae Chinensis 8-16 part, Herba Violae 8-16 part, Herba Taraxaci 8-16 part, Radix Angelicae Sinensis 8-16 part, Natrii Sulfas 3-9 part, Alumen 3-9 part, Herb Polygoni Chinensis 8-16 part, Flos Sophorae 8-16 part, Flos Lonicerae 8-16 part, Pericarpium Zanthoxyli 8-16 part, Herba Artemisiae Scopariae 8-16 part, Folium Artemisiae Argyi 8-16 part.
Preferably, the above-mentioned Chinese medicine for hemorrhoid, by the raw material of Chinese medicine medicine of following weight portion, made:
Flos Paulowniae 28-32 part, Radix Sanguisorbae 5-7 part, Herba Diclipterae Chinensis 10-14 part, Herba Violae 10-14 part, Herba Taraxaci 10-14 part, Radix Angelicae Sinensis 10-14 part, Natrii Sulfas 5-7 part, Alumen 5-7 part, Herb Polygoni Chinensis 10-14 part, Flos Sophorae 10-14 part, Flos Lonicerae 10-14 part, Pericarpium Zanthoxyli 10-14 part, Herba Artemisiae Scopariae 10-14 part, Folium Artemisiae Argyi 10-14 part.
Preferred, the above-mentioned Chinese medicine for hemorrhoid, by the raw material of Chinese medicine medicine of following weight portion, made:
30 parts of Flos Paulowniaes, 6 parts of Radix Sanguisorbaes, 12 parts of Herba Diclipterae Chinensis, 12 parts of Herba Violaes, 12 parts of Herba Taraxacis, 12 parts of Radix Angelicae Sinensis, 6 parts, Natrii Sulfas, 6 parts of Alumens, 12 parts of Herb Polygoni Chinensiss, 12 parts, Flos Sophorae, 12 parts of Flos Loniceraes, 12 parts, Pericarpium Zanthoxyli, 12 parts of Herba Artemisiae Scopariaes, 12 parts of Folium Artemisiae Argyis.
The Chinese medicine for hemorrhoid of the above, the dosage form of this Chinese medicine is oral formulations.
Preferably, the above-mentioned Chinese medicine for hemorrhoid, the dosage form of this Chinese medicine is external wash liquid.
The Chinese medicine external washing liquid preparation method for hemorrhoid of the above, comprises the steps:
A, takes various raw materials according to required weight portion;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time injection volume 5-7 times of water gaging and decoct 1-2 hour, add for the second time injection volume 3-5 times of water gaging and decoct 0.5-1.5 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.23～1.26 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 75% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, adds the water dilution of equivalent, stirs evenly, and 2～5 ℃ of standing cold preservations 24 hours again, filter, and obtain filtrate;
D, the aqueous solution that step a makes after distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000 parts, filter, sterilizing, obtains.
Preferably, the above-mentioned Chinese medicine external washing liquid preparation method for hemorrhoid, in described step c, to decoct with water in process amount of water be for the first time injection volume 6 times, decoct 1.5 hours; Amount of water is injection volume 4 times for the second time, decocts 1 hour.
The above-mentioned Chinese medicine external washing liquid preparation method for hemorrhoid, detailed step is as follows:
A, takes Flos Paulowniae 30g, Radix Sanguisorbae 6g, Herba Diclipterae Chinensis 12g, Herba Violae 12g, Herba Taraxaci 12g, Radix Angelicae Sinensis 12g, Natrii Sulfas 6g, Alumen 6g, Herb Polygoni Chinensis 12g, Flos Sophorae 12g, Flos Lonicerae 12g, Pericarpium Zanthoxyli 12g, Herba Artemisiae Scopariae 12g, Folium Artemisiae Argyi 12g raw material;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, adding for the first time 6 times of water gagings of injection volume decocts 1.5 hours, adding for the second time 4 times of water gagings of injection volume decocts 1 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.23～1.26 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 75% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, adds the water dilution of equivalent, stirs evenly, and 2～5 ℃ of standing cold preservations 24 hours again, filter, and obtain filtrate;
D, the aqueous solution that step a makes after distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, obtains.
Chinese medicine ingredients raw material for hemorrhoid of the present invention,
Flos Paulowniae is the flower of dicotyledon medicine goatweed Paulownia Paulownia fortunei (Seem.) Hemsl. or royal paulownia P. Tomentosa (Thunb.) Steud..Bitter, pungent, put down into lung meridian.Wind-dispelling heat-dissipating, heat-clearing and toxic substances removing, liver heat removing and eyesight improving.Be usually used in controlling upper respiratory tract infection, bronchopneumonia, acute tonsillitis, bacillary dysentery, acute enteritis, acute conjunctivitis, parotitis, furuncle and phyma.
Herba Diclipterae Chinensis has another name called Herba Strobilanthis tetraspermi, Huang Suede grass, is the herb of dicotyledon medicine acanthaceous plant Herba Strobilanthis tetraspermi Strobilanthes tetraspermus (Champ. Ex Benth.) Druce.There is heat-clearing and toxic substances removing, removing heat from blood, promote the production of body fluid, the effect of diuresis; With controlling the maculopapulae due to toxic heat tied in excess-heat, have blood in stool, the disease such as dysuria, toxic swelling furuncle; External can be with controlling traumatic injury, red and swollen hemorrhage.
It is the herb of Polygonaceae arsesmart Herb Polygoni Chinensis Polygunum chinense L. that Herb Polygoni Chinensis has another name called meal rattan, Linesless charcoal rattan, Herba Polygoni cymosi, river seven, plain rice grass clearly.The four seasons can adopt, and clean and dry or using fresh herb.Have heat-clearing and toxic substances removing, dampness removing disappears stagnant, blood-cooling itch-relieving, the effect of improving acuity of vision and removing nebula.The clinical dysentery that is used for, enteritis, dyspepsia, hepatitis, flu, tonsillitis, pharyngolaryngitis, diphtheria, pertussis, corneal nebula, colpitis mycotica, leucorrhea, mastitis, furuncle and phyma, children's's impetigo, eczema, venom.
Other Radix Sanguisorbae, Herba Violae, Herba Taraxaci, Radix Angelicae Sinensis, Natrii Sulfas, Alumen, Flos Sophorae, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, 2010 editions medical materials that record of the equal Chinese Pharmacopoeia of Folium Artemisiae Argyi.
The usage and dosage of lotion of medication of the present invention is: with the lotion of medication of the present invention (get this product 100ml and add warm water to 500ml, mix) of 20% concentration, boil temperature and smoke and wash anus position; Or with irrigator, the lotion of medication of the present invention of 10% concentration is delivered to deep rectum and rinse anus.2-3 time on the one 7 days is a course for the treatment of.
Chinese medicine for hemorrhoid of the present invention, has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, and the effect of cooling blood for hemostasis, for various types of hemorrhoid.
Chinese medicine fumigation and washing is one of important external treatment of traditional Chinese medical science anorectal surgical, it is the traditional method for the treatment of hemorrhoid, fumigation and wash method refers to the smoked affected part of medicine vapour of borrowing transpiration, again by affected part demibain in medicinal liquid, rely on its efficacy of a drug and heating power to directly act on pathological change of anorectal position, make this place's space between skin and muscles dredging, QI and blood is smooth, thereby reaches heat clearing and damp drying, promoting blood circulation and detumescence, analgesic hemostatic, convergence itching-relieving efficacies.Treatment skin infection is had to special effect, and day has no side effect.
Chinese medicine thinks, the generation of hemorrhoid disease is mostly by eating and drinking without temperance, rheumatism downward attack by pathogenic heat large intestine, and pyretic toxicity pents up, heat in blood dryness of the intestine, poly-loose the forming of knot.Chinese medicine for hemorrhoid of the present invention, compatibility is reasonable, and prescription is precise and appropriate.Full side has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, the effect of cooling blood for hemostasis, Flos Paulowniae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Flos Lonicerae, Herba Artemisiae Scopariae heat-clearing and toxic substances removing in side, dampness detumescence, purging heat to relax the bowels, removing toxicity for eliminating carbuncles, clots absorbing stimulates the menstrual flow, removing damp-heat, cooling blood for hemostasis; Natrii Sulfas purges heat, and moisturizes softening the hard mass; External can be controlled all kinds of skin infection carbuncle, has blood in stool etc.; Flos Sophorae cooling blood for hemostasis; Radix Angelicae Sinensis promoting blood circulation to remove obstruction in the collateral, eliminating stasis to stop pain; Alumen convergence is astringent or styptic treatment for spontaneous sweating; Pericarpium Zanthoxyli, Folium Artemisiae Argyi, Radix Angelicae Pubescentis are dispelled cold-damp.Take a broad view of full side, medication is precise and appropriate, and compatibility is rigorous, and all medicines share, the pathogenesis that hits, the effect of playing altogether heat clearing and damp drying, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain.For various types of hemorrhoid, with the passing of time it be applicable to the course of disease, the patient who repeatedly shows effect, and curative effect is better more outstanding.
The invention has the advantages that:
(1) the invention provides a kind of new Chinese medicine for hemorrhoid, met clinical needs.
(2) Chinese drug preparation that the present invention is used for hemorrhoid by treatment becomes washing liquid, easy to use, and patient's no pain has been avoided pain and the post-operative complication of performing the operation.
(3) clinical test results shows, compares with matched group, the Chinese medicine for hemorrhoid of the present invention, and cure rate is up to 68.42%, and matched group cure rate only has 23.21%, both have significant difference (p < 0.01); Total effective rate is up to 96.49%, and matched group effective percentage only have 48.28% both there is significant difference (p < 0.01).
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Prescription: Flos Paulowniae 30g, Radix Sanguisorbae 6g, Herba Diclipterae Chinensis 12g, Herba Violae 12g, Herba Taraxaci 12g, Radix Angelicae Sinensis 12g, Natrii Sulfas 6g, Alumen 6g, Herb Polygoni Chinensis 12g, Flos Sophorae 12g, Flos Lonicerae 12g, Pericarpium Zanthoxyli 12g, Herba Artemisiae Scopariae 12g, Folium Artemisiae Argyi 12g.
Preparation method:
A, takes Flos Paulowniae 30g, Radix Sanguisorbae 6g, Herba Diclipterae Chinensis 12g, Herba Violae 12g, Herba Taraxaci 12g, Radix Angelicae Sinensis 12g, Natrii Sulfas 6g, Alumen 6g, Herb Polygoni Chinensis 12g, Flos Sophorae 12g, Flos Lonicerae 12g, Pericarpium Zanthoxyli 12g, Herba Artemisiae Scopariae 12g, Folium Artemisiae Argyi 12g;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, adding for the first time 6 times of water gagings of injection volume decocts 1.5 hours, adding for the second time 4 times of water gagings of injection volume decocts 1 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.23～1.26 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 75% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, adds the water dilution of equivalent, stirs evenly, and 2～5 ℃ of standing cold preservations 24 hours again, filter, and obtain filtrate;
D, the aqueous solution that step a makes after distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, obtains.
Embodiment 2
Prescription: Flos Paulowniae 28g, Radix Sanguisorbae 7g, Herba Diclipterae Chinensis 10g, Herba Violae 14g, Herba Taraxaci 10g, Radix Angelicae Sinensis 14g, Natrii Sulfas 5g, Alumen 7g, Herb Polygoni Chinensis 10g, Flos Sophorae 14g, Flos Lonicerae 10g, Pericarpium Zanthoxyli 14g, Herba Artemisiae Scopariae 10g, Folium Artemisiae Argyi 14g.
Preparation method:
A, takes Flos Paulowniae 28g, Radix Sanguisorbae 7g, Herba Diclipterae Chinensis 10g, Herba Violae 14g, Herba Taraxaci 10g, Radix Angelicae Sinensis 14g, Natrii Sulfas 5g, Alumen 7g, Herb Polygoni Chinensis 10g, Flos Sophorae 14g, Flos Lonicerae 10g, Pericarpium Zanthoxyli 14g, Herba Artemisiae Scopariae 10g, Folium Artemisiae Argyi 14g;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, adding for the first time 7 times of water gagings of injection volume decocts 2 hours, adding for the second time 3 times of water gagings of injection volume decocts 0.5 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.23～1.26 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 75% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, adds the water dilution of equivalent, stirs evenly, and 2～5 ℃ of standing cold preservations 24 hours again, filter, and obtain filtrate;
D, the aqueous solution that step a makes after distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, obtains.
Embodiment 3
Prescription: Flos Paulowniae 32g, Radix Sanguisorbae 5g, Herba Diclipterae Chinensis 14g, Herba Violae 10g, Herba Taraxaci 14g, Radix Angelicae Sinensis 10g, Natrii Sulfas 7g, Alumen 5g, Herb Polygoni Chinensis 14g, Flos Sophorae 10g, Flos Lonicerae 14g, Pericarpium Zanthoxyli 10g, Herba Artemisiae Scopariae 14g, Folium Artemisiae Argyi 10g.
Preparation method:
A, takes Flos Paulowniae 32g, Radix Sanguisorbae 5g, Herba Diclipterae Chinensis 14g, Herba Violae 10g, Herba Taraxaci 14g, Radix Angelicae Sinensis 10g, Natrii Sulfas 7g, Alumen 5g, Herb Polygoni Chinensis 14g, Flos Sophorae 10g, Flos Lonicerae 14g, Pericarpium Zanthoxyli 10g, Herba Artemisiae Scopariae 14g, Folium Artemisiae Argyi 10g;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, adding for the first time 5 times of water gagings of injection volume decocts 1 hour, adding for the second time 5 times of water gagings of injection volume decocts 1.5 hours, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.23～1.26 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 75% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, adds the water dilution of equivalent, stirs evenly, and 2～5 ℃ of standing cold preservations 24 hours again, filter, and obtain filtrate;
D, the aqueous solution that step a makes after distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, obtains.
Embodiment 4
Prescription: 36 parts of Flos Paulowniaes, 3 parts of Radix Sanguisorbaes, 6 parts of Herba Diclipterae Chinensis, 8 parts of Herba Violaes, 16 parts of Herba Taraxacis, 8 parts of Radix Angelicae Sinensis, 9 parts, Natrii Sulfas, 3 parts of Alumens, 16 parts of Herb Polygoni Chinensiss, 8 parts, Flos Sophorae, 16 parts of Flos Loniceraes, 8 parts, Pericarpium Zanthoxyli, 16 parts of Herba Artemisiae Scopariaes, 8 parts of Folium Artemisiae Argyis.
Preparation method is with embodiment 1.
Embodiment 5
Prescription: Flos Paulowniae 24g, Radix Sanguisorbae 9g, Herba Diclipterae Chinensis 8g, Herba Violae 16g, Herba Taraxaci 8g, Radix Angelicae Sinensis 16g, Natrii Sulfas 3g, Alumen 9g, Herb Polygoni Chinensis 8g, Flos Sophorae 16g, Flos Lonicerae 8g, Pericarpium Zanthoxyli 16g, Herba Artemisiae Scopariae 8g, Folium Artemisiae Argyi 16g.
Preparation method is with embodiment 1.
The preparation of embodiments of the invention l has been carried out to clinical pharmacodynamics test, and result is as follows:
Patient is totally 226 examples, is divided at random 2 groups.In treatment group 114 examples, male 63 examples, female's 51 examples; 16 ~ 68 years old age, 38 years old mean age; The course of disease≤7 day 79 examples, 7 days 35 examples of course of disease >.In matched group 112 examples, male 62 examples, female's 50 examples; 18～65 years old age, 37 years old mean age; The course of disease≤7 day 76 examples, 7 days 36 examples of course of disease >.The physical data such as two groups of Genders, age, the course of disease, the state of an illness are there was no significant difference (P > O.05) relatively, has comparability.
2 Therapeutic Method
2.1 treatment groups: boil temperature with the lotion of medication of the present invention (get this product 100ml and add warm water to 500ml, mix) of 20% concentration and smoke and wash anus position, each 15 minutes.Attention: should be first before fumigation and wash method clean affected part by warm water, and then first smoke afterwards and wash with medicine juice, medicine soup temperature be take hands and is placed in water and do not scald as spending.
2.2 matched groups: adopt 0.02 % (1:5000) potassium permanganate solution 1500ml, fumigation and wash method demibain; Outer painting erythromycin ointment, every day 1 time.
Two groups equal every day fumigation and wash method 2 times, each 30min, continuous 7 days is 1 course for the treatment of.Finish rear judgement curative effect 1 course for the treatment of.
3 observation of curative effect
3.1 criterions of therapeutical effect: effective: symptom is obviously improved, anus edge is swollen, thrombosis lump dwindles degree > 2/3; Effective: symptom is improved, anus edge edema, thrombosis lump absorb and reach 1/3～2/3; Invalid: symptom is not improved, anus edge edema, thrombosis lump dwindle degree <1/3.
3.2 therapeutic outcomes: in Table 1.
Table 1 liang group therapeutic effect comparison
| Group | Number of cases | Effective | Effectively | Invalid | Cure rate (%) | Total effective rate (%) |
| Treatment group | 114 | 78 | 32 | 4 | 68.42* | 96.49* |
| Matched group | 112 | 26 | 28 | 57 | 23.21 | 48.28 |
Note: in matched group comparison, p < 0.01.
Compare with matched group, the Chinese medicine for hemorrhoid of the present invention, cure rate is up to 68.42%, and matched group cure rate only has 23.21%, both have significant difference (p < 0.01); Total effective rate is up to 96.49%, and matched group effective percentage only have 48.28% both there is significant difference (p < 0.01).
Claims (8)
1. for a Chinese medicine for hemorrhoid, by the raw material of Chinese medicine medicine of following weight portion, made:
Flos Paulowniae 24-36 part, Radix Sanguisorbae 3-9 part, Herba Diclipterae Chinensis 8-16 part, Herba Violae 8-16 part, Herba Taraxaci 8-16 part, Radix Angelicae Sinensis 8-16 part, Natrii Sulfas 3-9 part, Alumen 3-9 part, Herb Polygoni Chinensis 8-16 part, Flos Sophorae 8-16 part, Flos Lonicerae 8-16 part, Pericarpium Zanthoxyli 8-16 part, Herba Artemisiae Scopariae 8-16 part, Folium Artemisiae Argyi 8-16 part.
2. the Chinese medicine for hemorrhoid according to claim 1, is characterized in that, by the raw material of Chinese medicine medicine of following weight portion, is made:
Flos Paulowniae 28-32 part, Radix Sanguisorbae 5-7 part, Herba Diclipterae Chinensis 10-14 part, Herba Violae 10-14 part, Herba Taraxaci 10-14 part, Radix Angelicae Sinensis 10-14 part, Natrii Sulfas 5-7 part, Alumen 5-7 part, Herb Polygoni Chinensis 10-14 part, Flos Sophorae 10-14 part, Flos Lonicerae 10-14 part, Pericarpium Zanthoxyli 10-14 part, Herba Artemisiae Scopariae 10-14 part, Folium Artemisiae Argyi 10-14 part.
3. the Chinese medicine for hemorrhoid according to claim 2, is characterized in that, by the raw material of Chinese medicine medicine of following weight portion, is made:
30 parts of Flos Paulowniaes, 6 parts of Radix Sanguisorbaes, 12 parts of Herba Diclipterae Chinensis, 12 parts of Herba Violaes, 12 parts of Herba Taraxacis, 12 parts of Radix Angelicae Sinensis, 6 parts, Natrii Sulfas, 6 parts of Alumens, 12 parts of Herb Polygoni Chinensiss, 12 parts, Flos Sophorae, 12 parts of Flos Loniceraes, 12 parts, Pericarpium Zanthoxyli, 12 parts of Herba Artemisiae Scopariaes, 12 parts of Folium Artemisiae Argyis.
4. according to the Chinese medicine for hemorrhoid described in claim 1 or 2 or 3, it is characterized in that, the dosage form of this Chinese medicine is oral formulations.
5. the Chinese medicine for hemorrhoid according to claim 4, is characterized in that, the dosage form of this Chinese medicine is external wash liquid.
6. the Chinese medicine external washing liquid preparation method for hemorrhoid claimed in claim 1, comprises the steps:
According to required weight portion, take various raw materials;
By Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time injection volume 5-7 times of water gaging and decoct 1-2 hour, add for the second time injection volume 3-5 times of water gaging and decoct 0.5-1.5 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.23～1.26 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 75% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, adds the water dilution of equivalent, stirs evenly, and 2～5 ℃ of standing cold preservations 24 hours again, filter, and obtain filtrate;
The aqueous solution that step a makes after distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000 parts, filter, sterilizing, obtains.
7. the Chinese medicine external washing liquid preparation method for hemorrhoid according to claim 6, is characterized in that, in described step c, to decoct with water in process amount of water be for the first time injection volume 6 times, decoct 1.5 hours; Amount of water is injection volume 4 times for the second time, decocts 1 hour.
8. the Chinese medicine external washing liquid preparation method for hemorrhoid according to claim 6, detailed step is as follows:
A, takes Flos Paulowniae 30g, Radix Sanguisorbae 6g, Herba Diclipterae Chinensis 12g, Herba Violae 12g, Herba Taraxaci 12g, Radix Angelicae Sinensis 12g, Natrii Sulfas 6g, Alumen 6g, Herb Polygoni Chinensis 12g, Flos Sophorae 12g, Flos Lonicerae 12g, Pericarpium Zanthoxyli 12g, Herba Artemisiae Scopariae 12g, Folium Artemisiae Argyi 12g raw material;
B, by Flos Paulowniae, Radix Angelicae Sinensis, Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
C, by the medicinal residues after Radix Sanguisorbae, Herba Diclipterae Chinensis, Herba Violae, Herba Taraxaci, Herb Polygoni Chinensis, Flos Sophorae and above-mentioned distillating extracting oil, decoct with water extraction secondary, adding for the first time 6 times of water gagings of injection volume decocts 1.5 hours, adding for the second time 4 times of water gagings of injection volume decocts 1 hour, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.23～1.26 concentrated solution that 60 ℃ of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 75% containing alcohol amount, stirs evenly, and standing 12 hours of room temperature, filters; 60 ℃ of filtrates are reclaimed ethanol and are concentrated into relative density is 1.06～1.10, adds the water dilution of equivalent, stirs evenly, and 2～5 ℃ of standing cold preservations 24 hours again, filter, and obtain filtrate;
D, the aqueous solution that step a makes after distillation mixes with the filtrate of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 3000ml, filter, sterilizing, obtains.
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| CN104127737A (en) * | 2014-08-18 | 2014-11-05 | 朱秀芳 | Pharmaceutical composition for preventing and treating postoperative complications of haemorrhoids and preparation method of pharmaceutical composition |
| CN104398683A (en) * | 2014-11-07 | 2015-03-11 | 朱海燕 | Traditional Chinese medicine for treating constipation, preparation method and application thereof |
| CN107715018A (en) * | 2017-11-28 | 2018-02-23 | 李立金 | Treat the Chinese medicine composition of hemorrhoid |
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| CN1775251A (en) * | 2005-11-18 | 2006-05-24 | 石训义 | Method for preparing piles-treating Chinese modicine |
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| 王明轩: "中药口服加外洗治疗痔疮", 《内蒙古中医药》 * |
| 魏婧婧等: "中药治疗痔疮概述", 《实用中医药杂志》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104127737A (en) * | 2014-08-18 | 2014-11-05 | 朱秀芳 | Pharmaceutical composition for preventing and treating postoperative complications of haemorrhoids and preparation method of pharmaceutical composition |
| CN104398683A (en) * | 2014-11-07 | 2015-03-11 | 朱海燕 | Traditional Chinese medicine for treating constipation, preparation method and application thereof |
| CN107715018A (en) * | 2017-11-28 | 2018-02-23 | 李立金 | Treat the Chinese medicine composition of hemorrhoid |
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