CN108815453A - A kind of drug and preparation method thereof for treating ulcer of the cornea - Google Patents

Abstract

The invention discloses a kind of drugs and preparation method thereof for treating ulcer of the cornea, it is mainly prepared by dandelion, rough gentian, cassia seed, Lasiosphaera fenzlii, folium isatidis, honeysuckle, wild chrysanthemum, rhizoma alismatis, viola mandshurica, radix semiaquilegiae, the seed of feather cockscomb, Snakegourd Fruit, Fructus Aurantii, cape jasmine, Radix Isatidis, fructus viticis, cardamom, reed root according to a certain weight ratio, drug of the present invention has clearing heat and detoxicating, purging the liver of pathogenic fire excess fire, except damp-heat in lower-JIAO, improving eyesight, wind-dispelling heat, the function of invigorating the spleen, ulcer of the cornea is quick, good effect for treating, and does not recur.

Description

A kind of drug and preparation method thereof for treating ulcer of the cornea

Technical field

The present invention relates to a kind of drugs and preparation method thereof for treating ulcer of the cornea, belong to the field of Chinese medicines.

Technical background

Cornea is the film of the layer of transparent of eyeball foremost, is often exposed in air, and contact germ chance is more.Chang Yin The wounds such as foreign matter, are damaged after corneal foreign matter removing and trachoma and its complication, varus trichiasis stab cornea, bacterium, virus or Fungi avails oneself of the opportunity to get in, and causes to infect and ulcer of the cornea occurs.Chinese medicine then thinks ulcer of the cornea and the narrow wind of interior heat, yin asthenia generating intrinsic heat, liver Sthenia gastropyrexia, heat toxin heap soil or fertilizer over and around the roots fill pass.Since western medicine side effect is big, Chinese medicine of the people to effective treatment ulcer of the cornea There are great demands, up to now, it has not been found that about related report of the invention.

Summary of the invention

Repeatedly verifying of the present inventor according to research and the clinical test of theory of traditional Chinese medical science has finally found effectively treatment cornea The drug of ulcer, so as to complete the present invention.

It is an object of the invention to provide a kind of Chinese medicine compositions of effectively treatment ulcer of the cornea.

Another aim of the present invention is to provide the preparation methods of the Chinese medicine composition.

The present invention is selection dandelion, rough gentian, cassia seed, Lasiosphaera fenzlii, folium isatidis, honeysuckle, wild chrysanthemum, rhizoma alismatis, pale reddish brown Fourth, radix semiaquilegiae, the seed of feather cockscomb, Snakegourd Fruit, Fructus Aurantii, cape jasmine, Radix Isatidis, fructus viticis, cardamom, butterflybush flower, radices trichosanthis, fructus lycii, Radix Paeoniae Alba, Uncaria, Fructus Forsythiae, scouring rush, semen coicis, the shell of seaear, reed root, lophatherum gracile, Radix Glycyrrhizae, cicada slough, tribulus terrestris, aloe drug are combined system Standby, make each efficacy of drugs generate synergistic effect these pharmaceutical compositions, so as to effectively treat ulcer of the cornea.Wherein select It with dandelion being trembled with fear, enters liver, stomach meridian because of its nature and flavor bitter sweet, have clearing heat and detoxicating, the function of diuresis dissipating bind controls acute mastitis, Adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, liver Inflammation, cholecystitis, urinary tract infections.Selecting rough gentian is to tremble with fear because its is bitter in taste, enter liver, gallbladder channel, there is purging the liver of pathogenic fire excess fire, remove damp-heat in lower-JIAO Function, it is manic to control Liver Channel excess heat , Jing Epilepsy, encephalitis B, headache, hot eyes, pharyngalgia, jaundice, hot dysentery, carbuncle swells sore, and scrotum is swollen Bitterly, private parts is wet itches.Select cassia seed be because of its nature and flavor bitter sweet, it is cool, enter liver and kidney channel, there is clearing liver, improving eyesight, Li Shui, the function of defaecation Can, control wind-heat cute conjunctivitis, optic atrophy, night blindness, hypertension, hepatitis, cirrhosis abdomen, habitual constipation.Selecting Lasiosphaera fenzlii is because of its property Acrid flavour puts down, enters lung channel, there is removing heat from the lung and relieving sorethroat, removing toxic substances, the function of hemostasis, controls larynx numbness pharyngalgia, and cough with aphonia spits blood, bleeding from five sense organs or subcutaneous tissue, wound Bleeding.Selecting folium isatidis is to tremble with fear because its is bitter in taste, enter liver, the heart, stomach meridian, there is heat-clearing, detoxify, cool blood, the function of hemostasis is controlled Warm disease excess heat polydipsia, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas are spitted blood, nosebleed Blood, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Selecting honeysuckle is to tremble with fear because its nature and flavor is sweet, enter lung, stomach meridian, there is heat-clearing, The function of removing toxic substances controls warm disease heating, toxic-heat and blood stasis, large carbuncle, pyogenic infections, scrofula, anal fistula.With wild chrysanthemum be because of its nature and flavor toil, It is cool, enter lung, Liver Channel, there is a dispelling wind and heat, the function of subdhing swelling and detoxicating controls anemopyretic cold, pneumonia, diphtheria, gastroenteritis, hypertension, malignant boil, Carbuncle, aphtha, erysipelas, eczema, epidemic blisters.Rhizoma alismatis is to tremble with fear because its nature and flavor is sweet, enter bladder meridian, advantageous water, excreting dampness, the function to expel the heat-evil Can, difficult urination is controlled, oedema anus is full, vomiting, dysentery, phlegm retention, tinea pedis, stranguria syndrome, hematuria.Selecting viola mandshurica is because of its nature and flavor Bitter, acrid, cold, converge to heart and liver channels have clearing heat and detoxicating, the function of cool blood detumescence, control furuncle swelling toxin, ulcer carbuncle on the back, erysipelas, and poisonous snake stings Wound.Selecting radix semiaquilegiae is trembled with fear because of its nature and flavor sweetness and bitterness, is entered spleen, small intestine, bladder three and is passed through, has heat-clearing, detoxify, detumescence, dissipating bind, benefit The function of urine controls carbuncle swells, scrofula, furunculosis, stranguria with turbid discharge, leukorrhagia, cough due to deficiency of the lung, hernia , Dian Epilepsy, child convulsion, hemorrhoid, bruise damage Wound.Select the seed of feather cockscomb be because its is bitter in taste, it is cool, enter Liver Channel, have wind-dispelling hot, the function of clearing away the liver-fire controls red eye, swell pain, hides from view, Hypertension, nosebleed epistaxis, skin wind-heat itch, scabies leprosy.Selecting Snakegourd Fruit is sweet, slight bitter because of its nature and flavor, is trembled with fear, return lung, stomach, large intestine channel, There are clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, the function of moisturizing dryness and lubricating intestine controls cough with lung heat, yellow and thick phlegm, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, cream Carbuncle, acute appendicitis, constipation.Select Fructus Aurantii be because of its nature and flavor toil, it is cool, enter lung, spleen, large intestine channel, there is relieving stagnant Qi, row phlegm, disperse accumulation Function, it is stagnant to control chest diaphragm phlegm, the feeling of stuffiness in chest, coerces swollen, dyspepsia, and gas is vomitted inverse, weight, rectal prolapse, uterine prolapse after diarrhea.Selecting cape jasmine is Because its is bitter in taste, trembles with fear, enter the heart, liver, lung, stomach meridian, there is heat-clearing, purging intense heat, the function of cool blood controls pyreticosis restlessness of asrhenia type and insomnia, jaundice, leaching Disease is quenched one's thirst, hot eyes, pharyngalgia, is spitted blood, bleeding from five sense organs or subcutaneous tissue, bloody flux, hematuria, and pathopyretic ulcer sprains swelling and pain.Selecting Radix Isatidis is because of its property Bitter trembles with fear, enters liver, stomach blood system, there is heat-clearing, detoxifies, the function of cool blood, controls influenza, epidemic meningitis, encephalitis, pneumonia, erysipelas, heat toxin hair Spot, coma hematemesis, pharynx swelling, mumps, acute conjunctivitis, sore rash.Select fructus viticis be because of its nature and flavor toil, it is cool, enter liver, stomach, bladder meridian, There is dispelling wind and heat from the body, the function of head clearing controls anemopyretic cold, just, migraine, and dentalgia, pain in mesh eyeball.Selecting cardamom is because of it Nature and flavor are acrid in flavour and warm in nature, enter lung, the spleen channel, there is row wind, and warm stomach helps digestion, it is wide in function, control the stagnation of the circulation of vital energy, food stagnation is uncomfortable in chest, abdominal distension, gas, choke Diaphragm spits inverse, gastric disorder causing nausea, malaria.It selects butterflybush flower and is because its nature and flavor is sweet, it is cool, enter Liver Channel, there is a wind-dispelling, cool blood moistens liver, improving eyesight Function controls red eye, swell pain, more tear photophobia, optic atrophy ocular, the rotten eye of wind string.Selecting radices trichosanthis is entered because its nature and flavor sweetness and bitterness acid, cool Lung, stomach meridian, have and promote the production of body fluid, and quench the thirst, and fall fire is moisturized, apocenosis, the function of detumescence, and it is thirsty to control pyreticosis, quench one's thirst, jaundice, dryness of the lung hemoptysis, Carbuncle swells, hemorrhoid complicated by anal fistula.Selecting fructus lycii is to have a nourshing kidney because of its nature and flavor sweet and neutral, moistening lung, tonifying liver, and the function of improving eyesight controls liver-kidney Yin deficiency, Soreness and weakness of waist and knees is had a dizzy spell, and the more tears of blurred vision, cough due to consumptive disease is quenched one's thirst, and is lost clear.Select Radix Paeoniae Alba be because of its nature and flavor picric acid, it is cool, enter Liver, the spleen channel, there is nourishing blood and liver, delay in analgesic, the function of contagious yin controls chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, Fever due to yin deficiency, irregular menstruation, metrorrhagia and metrostaxis, leukorrhagia.Select uncaria be because its is bitter in taste, it is cool, enter liver, the heart channel of Hang-Shaoyin, there is The flat liver of heat-clearing, put out The function of wind arresting convulsion, controls little Jing Epilepsy Chi Zong, adult's slight Hypertension is dizzy, dizzy, married woman's sub- Epilepsy.Selecting Fructus Forsythiae is because of it It is bitter in taste, it is cool, enter the heart, liver, gallbladder channel, there is heat-clearing, detoxifies, warm is controlled in dissipating bind, detumescence, erysipelas, macula, large carbuncle pyogenic infections, scrofula, Urine leaching closes.Selecting scouring rush is to put down because of its nature and flavor sweetness and bitterness, enter lung, liver, gallbladder channel, there is wind-dispelling heat-dissipating, and expelling pathogenic factors from muscles and skin moves back the function of screen, Control the raw cloudiness of mesh, tearing against wind, discharging fresh blood stool, bloody flux, rectal prolapse, malaria, laryngalgia, carbuncle swells.Selecting semen coicis is because of its nature and flavor It is sweet light, it is cool, enter spleen, lung, kidney channel, there is an invigorating the spleen, tonifying lung, heat-clearing, the function of dampness removing controls diarrhea, arthritis with fixed pain caused by dampness, and muscle arteries and veins contraction is bent and stretched not Benefit, oedema, tinea pedis, consumptive lung disease, pulmonary abscess, acute appendicitis, stranguria with turbid discharge, leukorrhea.Selecting the shell of seaear is to put down because its nature and flavor is salty, enter liver and kidney channel, Have calming the liver, except heat, the function of improving eyesight controls wind-yang and up-boring, and headache and dizziness is frightened to jerk, hectic fever due to yin labor heat, optic atrophy.Select reed Root is to tremble with fear because its nature and flavor is sweet, enter lung, stomach meridian has heat-clearing, promotes the production of body fluid, and relieving restlessness, the function of preventing or arresting vomiting controls pyreticosis and polydipsia, and stomach energy is vomitted It spits, dysphagic, gastric disorder causing nausea, consumptive lung disease, pulmonary abscess, and solves filefish ichthyotoxin.Selecting lophatherum gracile is to tremble with fear because of its property slightly sweet flavor, enter heart kidney two warp, There is a clearing away the heart-fire, relieving restlessness heat, the function of diuresis, it is thirsty to control pyreticosis, vexed, hot urination, stranguria with turbid discharge, aphthous stomatitis tongue boil, swelling and aching of gum. Selecting Radix Glycyrrhizae is to enter spleen, stomach, lung channel because of its sweet in flavor and neutral in nature, is had and middle emergency, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription, toast Weakness of the spleen and the stomach with controlling, deficiency of food, abdominal pain loose stool, overstrain fever, consumptive lung disease cough, palpitaition shies carbuncle, raw with controlling abscess of throat, digestibility Ulcer, ulcer sores solve poisoning of drug and food poisoning.Select cicada slough be because of its property sweet-salty, it is cool, enter lung, Liver Channel, there is relieve heat Heat, promoting the dispersing function of the lung determine the function of convulsion, control affection of exogenous wind-heat, hoarse voice of coughing, measles without adequate eruption, rubella itch, little Jing Epilepsy, hot eyes, screen Barrier, furuncle swelling toxin, tetanus.Selecting tribulus terrestris is to enter liver, lung channel because its is bitter in taste acrid in flavour and warm in nature, there is a relieve heat, improving eyesight, lower gas, The function of promoting circulation of blood controls headache, and body is itched, and hot eyes swells screen, fullness sensation in chest, cough Ni , Disorder lump in the abdomen, and cream is difficult, ulcer, scrofula.Select aloe be because Its is bitter in taste, trembles with fear, enters liver, the heart, the spleen channel, there is a heat-clearing, defaecation, the function of desinsection, controls constipation with heat retention, women's menostasis, little Jing Epilepsy, Infantile malnutrition with fever malnutrition due to parasitic infestation, tinea sore, hemorrhoid complicated by anal fistula, atrophic rhinitis, scrofula.

Specific embodiment

The drug dose of instant component is also to be obtained by plenty of explorations of the inventor, and the dosage of each component is following heavy All tools have a better effect in amount range：

15-25 grams of dandelion, 10-20 grams of rough gentian, 15-20 grams of cassia seed, 10-20 grams of Lasiosphaera fenzlii, 5-15 grams of folium isatidis, honeysuckle 10-20 grams, 10-15 grams of wild chrysanthemum, 10-15 grams of rhizoma alismatis, 10-20 grams of viola mandshurica, 10-20 grams of radix semiaquilegiae, seed of feather cockscomb 10-15 Gram, 10-20 grams of Snakegourd Fruit, 10-15 grams of Fructus Aurantii, 5-15 grams of cape jasmine, 10-20 grams of Radix Isatidis, 5-15 grams of fructus viticis, 10-15 grams of cardamom, 10-15 grams of butterflybush flower, 5-15 grams of radices trichosanthis, 10-20 grams of fructus lycii, 5-15 grams of Radix Paeoniae Alba, 10-15 grams of uncaria, 5-15 grams of Fructus Forsythiae, wood Crafty 10-20 grams, 10-20 grams of semen coicis, 10-20 grams of the shell of seaear, 5-15 grams of reed root, 10-15 grams of lophatherum gracile, 10-20 grams of Radix Glycyrrhizae, cicada Slough off 10-15 grams, 5-15 grams of tribulus terrestris, 5-10 grams of aloe.

Preferably：

20 grams of dandelion, 15 grams of rough gentian, 18 grams of cassia seed, 15 grams of Lasiosphaera fenzlii, 10 grams of folium isatidis, 15 grams of honeysuckle, 12 grams of wild chrysanthemum, 12 grams of rhizoma alismatis, 15 grams of viola mandshurica, 15 grams of radix semiaquilegiae, 12 grams of the seed of feather cockscomb, 15 grams of Snakegourd Fruit, 12 grams of Fructus Aurantii, 10 grams of cape jasmine, Radix Isatidis 15 grams, 10 grams of fructus viticis, 12 grams of cardamom, 12 grams of butterflybush flower, 10 grams of radices trichosanthis, 15 grams of fructus lycii, 10 grams of Radix Paeoniae Alba, 12 grams of uncaria, 10 grams of Fructus Forsythiae, 15 grams of scouring rush, 15 grams of semen coicis, 15 grams of the shell of seaear, 10 grams of reed root, 12 grams of lophatherum gracile, 15 grams of Radix Glycyrrhizae, cicada slough 12 Gram, 10 grams of tribulus terrestris, 8 grams of aloe.

The preparation method of drug of the present invention is as follows

One, it stocks up

1, dandelion：Impurity is picked, soil is cleaned, dissection is dried；

2, rough gentian：Impurity is picked, residual stem is removed, is cleaned, is moisturized rear dissection, dry；

3, cassia seed：Net cassia seed is taken, sets and fries in pot to micro- aromatic, take out, cool；

4, Lasiosphaera fenzlii：Remove sclerderm, dice；

5, folium isatidis：Impurity and dead leaf are picked, cleans, slightly moistens, dissection is dried；

6, honeysuckle：Silt is weeded out, net impurity is picked；

7, wild chrysanthemum：Impurity is removed, undesirable root is removed, dissection is cleaned, dries；

8, rhizoma alismatis：Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, and solarization is cool, and bored profit is cut to uniform humidity inside and outside Piece dries；

9, viola mandshurica：Crude drug is taken, impurity is removed, cleans, slightly dries in the air, dissection is dry；

10, radix semiaquilegiae：Clear water is cleaned, and slice dries；

11, the seed of feather cockscomb：Harvesting, extracted aerial part or flower spike, dried 8~October, rubbed seed, removes impurity, dries；

12, Snakegourd Fruit：Crude drug is taken, impurity and carpopodium are removed, is cleaned, is flattened, chopping or fritter are dry；

13, Fructus Aurantii：Flesh, core are removed, edulcoration is slightly soaked, pulled out, softens, and can pinch doubling with hand as degree, slice dries；

14, cape jasmine：Grey bits are weeded out, impurity is picked, pulverize sieving or cut off both ends；

15, Radix Isatidis：Net impurity is picked, cleans, moisturizes, is sliced, dries；

16, fructus viticis：Well sifted ash bits remove remaining sepal, set and are fried with high heat in pot to coke yellow, slightly spray clear water, are cooled；

17, cardamom：Net impurity is picked, scurf is weeded out, is smashed, or peels off shell, kernel-taking smashes use；

18, butterflybush flower：Pick impurity, well sifted dirt；

19, radices trichosanthis：Impurity is picked, size block is separated, thoroughly with bubble about sixty percent, pulls out, and bored profit is cut to uniform humidity inside and outside Piece dries, or is eluted with water, and pulls out, shines to extremely dry, is pounded fritter；

20, fructus lycii：It winnows with a dustpan net impurity, plucks remaining stalk and the base of a fruit；

21, Radix Paeoniae Alba：Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit to uniform humidity inside and outside, Slice, it is dry；

22, uncaria：Old stalk, impurity are picked, cleans, dries；

23, Fructus Forsythiae：Net impurity is picked, is rubbed open, discarding stalk is removed；

24, scouring rush：It cleans, slightly moistens, cut off root, dissection is dried；

25, semen coicis：Crude drug is taken, residual leather shell, impurity are removed；

26, the shell of seaear：It cleans and dries, knock fragment；

27, reed root：Impurity and root are picked, dissection is dried；

28, lophatherum gracile：Impurity and root are picked, dissection is dried；

29, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, moisturize slice, dry；

30, cicada slough：Impurity is picked, cleans and dries；

31, tribulus terrestris：Silt, cleared remaining hard thorn are removed in drift；

32, aloe：Impurity is picked, fritter is hacked into.

Two, it prepares

1, by the dandelion of the weight, rough gentian, cassia seed, Lasiosphaera fenzlii, folium isatidis, honeysuckle, wild chrysanthemum, rhizoma alismatis, viola mandshurica, Radix semiaquilegiae, the seed of feather cockscomb, Snakegourd Fruit, Fructus Aurantii, cape jasmine, Radix Isatidis, fructus viticis, cardamom, butterflybush flower, radices trichosanthis, fructus lycii, Radix Paeoniae Alba, hook Rattan, Fructus Forsythiae, scouring rush, semen coicis, the shell of seaear, reed root, lophatherum gracile, Radix Glycyrrhizae, cicada slough, tribulus terrestris, aloe are put into decocting container, add 8 times of water amounts, after impregnating 100 minutes, high heat decoction boiling then with being cooked by slow fire 20 minutes, filters to obtain first time decoction liquor, by the One time decoction liquor is poured into container；

2, the dregs of a decoction of filtering are added into 6 times of water amounts, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；

3, it decoction liquor will be mixed evenly twice, and be divided into 4 doses and take.

Dandelion is clearing heat and detoxicating in prescription, and diuresis dissipating bind, rough gentian has purging the liver of pathogenic fire excess fire, except both functions of damp-heat in lower-JIAO are monarch Medicine；Cassia seed clears liver, improving eyesight, Li Shui, defaecation, and Lasiosphaera fenzlii has removing heat from the lung and relieving sorethroat, detoxifies, the function of hemostasis, with folium isatidis, honeysuckle, Wild chrysanthemum, rhizoma alismatis, viola mandshurica, radix semiaquilegiae are ministerial drug, and ten taste medicines play clearing heat and detoxicating, purging the liver of pathogenic fire excess fire jointly, except damp-heat in lower-JIAO, Improving eyesight, removing heat from the lung and relieving sorethroat, hemostasis effect, treatment ulcer of the cornea effect is comprehensive, and with clearing heat and detoxicating, purging the liver of pathogenic fire excess fire, except lower coke is wet Based on heat, improving eyesight, it can effect a permanent cure；The seed of feather cockscomb has that wind-dispelling is hot, the function and Snakegourd Fruit of clearing away the liver-fire, Fructus Aurantii, cape jasmine, Radix Isatidis, fructus viticis, Cardamom, butterflybush flower, radices trichosanthis, fructus lycii, Radix Paeoniae Alba, uncaria, Fructus Forsythiae, scouring rush are adjutant；Semen coicis has invigorating the spleen, tonifying lung, heat-clearing, benefit Wet function and remaining all medicines are to make medicine, are temporary solutions.

Drug of the present invention has clearing heat and detoxicating, purging the liver of pathogenic fire excess fire, except damp-heat in lower-JIAO, improving eyesight, wind-dispelling heat, the function of invigorating the spleen, uses In treatment ulcer of the cornea, short treating period, quick, non-relapse after healing.

The beneficial effect of the present invention will be further illustrated by the following test examples the drug, these test examples include this hair The animal toxicity test report of bright drug and clinical observation on the therapeutic effect data.

The animal toxicity test of [test example 1] drug of the present invention is reported：

Taking rabbit 30, male and female dual-purpose, 2.0-2.5kg of weight is divided to two groups, and every group 15, wherein one group is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, normal amount 10ml/kg, and administration mode gives for administration by gavage Medicine even served 7 days twice daily, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and drug is without bad Toxic side effect.

The clinical observation on the therapeutic effect of [test example 2] drug of the present invention

1, general information

Accept ulcer of the cornea out-patient totally 43 for medical treatment.

2, diagnostic criteria

Classical symptom is：It keeps in dark place, shed tears, occurring canescence dot or sheet infiltration etc. on ophthalmodynia, cornea.

3, treatment method

Above-mentioned medicament is selected, is taken to patient, each taking 1 dose, early daily, evening is respectively taken 1 time, and 7 days as a course for the treatment of, continuous to take With 3 courses for the treatment of.

4, efficacy assessment standard

It is effective：Ulcer of the cornea symptom disappears, and restores normal, recovery from illness；

It improves：Patient keeps in dark place, sheds tears, occurring the mitigation of the phenomenon that canescence dot or sheet infiltration, ulcer of the cornea on ophthalmodynia, cornea The symptoms were significantly improved, gradually restores normal；

In vain：Improvement standard person is not achieved.

5, treatment results（It see the table below）

In the above treatment, with drug therapy ulcer of the cornea patient 43 of the present invention, as a result effective 34, obvious effective rate is 79.07%, it improves 7, improvement rate 16.28%, invalid 2, total effective rate 95.35%.

Claims (3)

1. a kind of drug for treating ulcer of the cornea, it is characterised in that：It is made of the bulk pharmaceutical chemicals in following weight range：

15-25 grams of dandelion, 10-20 grams of rough gentian, 15-20 grams of cassia seed, 10-20 grams of Lasiosphaera fenzlii, 5-15 grams of folium isatidis, honeysuckle 10-20 grams, 10-15 grams of wild chrysanthemum, 10-15 grams of rhizoma alismatis, 10-20 grams of viola mandshurica, 10-20 grams of radix semiaquilegiae, seed of feather cockscomb 10-15 Gram, 10-20 grams of Snakegourd Fruit, 10-15 grams of Fructus Aurantii, 5-15 grams of cape jasmine, 10-20 grams of Radix Isatidis, 5-15 grams of fructus viticis, 10-15 grams of cardamom, 10-15 grams of butterflybush flower, 5-15 grams of radices trichosanthis, 10-20 grams of fructus lycii, 5-15 grams of Radix Paeoniae Alba, 10-15 grams of uncaria, 5-15 grams of Fructus Forsythiae, wood Crafty 10-20 grams, 10-20 grams of semen coicis, 10-20 grams of the shell of seaear, 5-15 grams of reed root, 10-15 grams of lophatherum gracile, 10-20 grams of Radix Glycyrrhizae, cicada Slough off 10-15 grams, 5-15 grams of tribulus terrestris, 5-10 grams of aloe.

2. drug according to claim 1, wherein the dosage of each bulk pharmaceutical chemicals is：

20 grams of dandelion, 15 grams of rough gentian, 18 grams of cassia seed, 15 grams of Lasiosphaera fenzlii, 10 grams of folium isatidis, 15 grams of honeysuckle, 12 grams of wild chrysanthemum, 12 grams of rhizoma alismatis, 15 grams of viola mandshurica, 15 grams of radix semiaquilegiae, 12 grams of the seed of feather cockscomb, 15 grams of Snakegourd Fruit, 12 grams of Fructus Aurantii, 10 grams of cape jasmine, Radix Isatidis 15 grams, 10 grams of fructus viticis, 12 grams of cardamom, 12 grams of butterflybush flower, 10 grams of radices trichosanthis, 15 grams of fructus lycii, 10 grams of Radix Paeoniae Alba, 12 grams of uncaria, 10 grams of Fructus Forsythiae, 15 grams of scouring rush, 15 grams of semen coicis, 15 grams of the shell of seaear, 10 grams of reed root, 12 grams of lophatherum gracile, 15 grams of Radix Glycyrrhizae, cicada slough 12 Gram, 10 grams of tribulus terrestris, 8 grams of aloe.

3. the preparation method of drug according to claim 1 or claim 2, it includes the following steps：

（One）Stock

（1）Dandelion：Impurity is picked, soil is cleaned, dissection is dried；

（2）Rough gentian：Impurity is picked, residual stem is removed, is cleaned, is moisturized rear dissection, dry；

（3）Cassia seed：Net cassia seed is taken, sets and fries in pot to micro- aromatic, take out, cool；

（4）Lasiosphaera fenzlii：Remove sclerderm, dice；

（5）Folium isatidis：Impurity and dead leaf are picked, cleans, slightly moistens, dissection is dried；

（6）Honeysuckle：Silt is weeded out, net impurity is picked；

（7）Wild chrysanthemum：Impurity is removed, undesirable root is removed, dissection is cleaned, dries；

（8）Rhizoma alismatis：Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, cool, bored profit to uniform humidity inside and outside is shone, Slice, is dried；

（9）Viola mandshurica：Crude drug is taken, impurity is removed, cleans, slightly dries in the air, dissection is dry；

（10）Radix semiaquilegiae：Clear water is cleaned, and slice dries；

（11）The seed of feather cockscomb：Harvesting, extracted aerial part or flower spike, dried 8~October, rubbed seed, removes impurity, dries；

（12）Snakegourd Fruit：Crude drug is taken, impurity and carpopodium are removed, is cleaned, is flattened, chopping or fritter are dry；

（13）Fructus Aurantii：Flesh, core are removed, edulcoration is slightly soaked, pulled out, softens, and can pinch doubling with hand as degree, slice dries；

（14）Cape jasmine：Grey bits are weeded out, impurity is picked, pulverize sieving or cut off both ends；

（15）Radix Isatidis：Net impurity is picked, cleans, moisturizes, is sliced, dries；

（16）Fructus viticis：Well sifted ash bits remove remaining sepal, set and are fried with high heat in pot to coke yellow, slightly spray clear water, are cooled；

（17）Cardamom：Net impurity is picked, scurf is weeded out, is smashed, or peels off shell, kernel-taking smashes use；

（18）Butterflybush flower：Pick impurity, well sifted dirt；

（19）Radices trichosanthis：Impurity is picked, size block is separated, thoroughly with bubble about sixty percent, pulls out, and bored profit is cut to uniform humidity inside and outside Piece dries, or is eluted with water, and pulls out, shines to extremely dry, is pounded fritter；

（20）Fructus lycii：It winnows with a dustpan net impurity, plucks remaining stalk and the base of a fruit；

（21）Radix Paeoniae Alba：Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit to uniform humidity inside and outside, Slice, it is dry；

（22）Uncaria：Old stalk, impurity are picked, cleans, dries；

（23）Fructus Forsythiae：Net impurity is picked, is rubbed open, discarding stalk is removed；

（24）Scouring rush：It cleans, slightly moistens, cut off root, dissection is dried；

（25）Semen coicis：Crude drug is taken, residual leather shell, impurity are removed；

（26）The shell of seaear：It cleans and dries, knock fragment；

（27）Reed root：Impurity and root are picked, dissection is dried；

（28）Lophatherum gracile：Impurity and root are picked, dissection is dried；

（29）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, moisturize slice, dry；

（30）Cicada slough：Impurity is picked, cleans and dries；

（31）Tribulus terrestris：Silt, cleared remaining hard thorn are removed in drift；

（32）Aloe：Impurity is picked, fritter is hacked into；

（Two）Preparation

（1）By the dandelion of the weight, rough gentian, cassia seed, Lasiosphaera fenzlii, folium isatidis, honeysuckle, wild chrysanthemum, rhizoma alismatis, pale reddish brown Fourth, radix semiaquilegiae, the seed of feather cockscomb, Snakegourd Fruit, Fructus Aurantii, cape jasmine, Radix Isatidis, fructus viticis, cardamom, butterflybush flower, radices trichosanthis, fructus lycii, Radix Paeoniae Alba, Uncaria, Fructus Forsythiae, scouring rush, semen coicis, the shell of seaear, reed root, lophatherum gracile, Radix Glycyrrhizae, cicada slough, tribulus terrestris, aloe are put into decocting container, Add 8 times of water amounts, after impregnating 100 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, it will First time decoction liquor is poured into container；

（2）The dregs of a decoction of filtering are added into 6 times of water amounts, are boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；

（3）It decoction liquor will be mixed evenly twice, and be divided into 4 doses and take.