CN108392565A - A kind of drug and preparation method thereof for treating otitis media suppurative - Google Patents

Abstract

The invention discloses a kind of drugs and preparation method thereof for treating otitis media suppurative, it is prepared according to a certain weight ratio by radix bupleuri, the root of Dahurain angelica, cape jasmine, radix paeoniae rubra, waxgourd seed, dandelion, rhizoma alismatis, rough gentian, chrysanthemum, stiff silkworm, uncaria, gypsum, Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong, radix rehmanniae recen, Fructus meliae toosendan, radix scutellariae, Cortex Phellodendri, cape jasmine, Fructus Forsythiae, schizonepeta, rhizoma anemarrhenae, drug of the present invention, which has, to dispel pathogenic wind and remove dampness, swelling and pain relieving, clearing heat and cooling blood, the function of removing blood stasis and analgesics, otitis media suppurative is quick, good effect for treating, and does not recur.

Description

A kind of drug and preparation method thereof for treating otitis media suppurative

Technical field

The present invention relates to a kind of drugs and preparation method thereof for treating otitis media suppurative, belong to the field of Chinese medicines.

Background technology

Otitis media suppurative refers to the purulent inflammation of middle ear mucosa, is apt to occur in children, is also the normal of children's hearing loss See the cause of disease.Childhood that acute suppurative otitis media is common infectious diseases, incidence is high, easily recurs, and complication and rear loses Disease is more.The auxiliary examinations such as otoscopy, ear's palpation help to make a definite diagnosis otitis media suppurative.Since western medicine side effect is big, Therefore there are great demands to the Chinese medicine of effectively treating otitis media suppurative by people, up to now, it has not been found that closing In the related report of the present invention.

Invention content

Repeatedly verification of the present inventor according to research and the clinical test of theory of traditional Chinese medical science has finally found effectively treatment and suppurates The drug of property tympanitis, so as to complete the present invention.

It is an object of the invention to provide a kind of Chinese medicine compositions of effective treatment otitis media suppurative.

Another aim of the present invention is to provide the preparation methods of the Chinese medicine composition.

Drug of the present invention is selection radix bupleuri, the root of Dahurain angelica, cape jasmine, radix paeoniae rubra, waxgourd seed, dandelion, rhizoma alismatis, rough gentian, chrysanthemum, deadlock Silkworm, uncaria, gypsum, Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong, radix rehmanniae recen, Fructus meliae toosendan, radix scutellariae, Cortex Phellodendri, cape jasmine, Fructus Forsythiae, schizonepeta, windproof, Fructus Aurantii, Prepared rehmannia root, moutan bark, Poria cocos, Fructus Corni, rhizoma anemarrhenae are combined preparation, each efficacy of drugs are generated these pharmaceutical compositions Synergistic effect, so as to effectively treat otitis media suppurative.Wherein selection radix bupleuri is bitter in taste because of its, cool, enters liver, courage Through having in inducing diaphoresis, soothing the liver, the function of rising Yang controls fevers and chills alternate, and fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower profit Rectal prolapse, irregular menstruation, metroptosis.It is to enter lung, spleen, stomach because its nature and flavor is acrid in flavour and warm in nature, have wind-dispelling, eliminating dampness to disappear to select the root of Dahurain angelica Swollen, the function of analgesic controls headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, Skin itchy, mange.It is to tremble with fear because its is bitter in taste, enter the heart, liver, lung, stomach, there is heat-clearing, purging intense heat, the work(of cool blood to select cape jasmine Can, pyreticosis restlessness of asrhenia type and insomnia, jaundice are controlled, gonorrhoea is quenched one's thirst, hot eyes, pharyngalgia, is spitted blood, bleeding from five sense organs or subcutaneous tissue, bloody flux, hematuria, and pathopyretic ulcer is sprained Swelling and pain.Selecting radix paeoniae rubra is slightly cold because its is bitter in taste, and return liver warp has clearing heat and cooling blood, the function of removing blood stasis and analgesics to control epidemic heat syndrome and go mad, Hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, closed dysmenorrhea , Epilepsy lump in the abdomen abdominal pain, injury from falling down, carbuncle swells sore.Select waxgourd seed be because It is sweet for its nature and flavor, it is cool, enter meridian of Foot-JUE YIN, there is moistening lung, resolving sputum, disappear carbuncle, the function of Li Shui, controls phlegm-heat cough, lung carbuncle, acute appendicitis, leaching Disease, oedema, tinea pedis, hemorrhoid, nasal surface wine Zha.It is to tremble with fear because of its nature and flavor bitter sweet, enter liver, stomach, there is heat-clearing solution to select dandelion Poison, the function of diuresis dissipating bind control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, urgency Property tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections.Selecting rhizoma alismatis is trembled with fear because its nature and flavor is sweet, Entering bladder warp, advantageous water, excreting dampness, the function of expelling the heat-evil controls difficult urination, and oedema anus is full, vomiting, rush down dysentery, phlegm and retained fluid, tinea pedis, gonorrhoea, Hematuria.It is to tremble with fear because its is bitter in taste, enter liver, gallbladder channel, there is purging the liver of pathogenic fire excess fire, remove the function of damp-heat in lower-JIAO to select rough gentian, controls Liver Channel heat It is manic to contain , Jing Epilepsy, encephalitis B, headache, hot eyes, pharyngalgia, jaundice, hot dysentery, carbuncle swells sore, scrotum swelling and pain, private parts is wet to itch.It selects Chrysanthemum be because of its nature and flavor sweetness and bitterness, it is cool, enter lung, Liver Channel has dispelling wind, and disappear heat, improving eyesight, and the function of removing toxic substances controls headache, dizziness, mesh It is red, ambition dysphoria with smothery sensation, furunculosis, pyogenic infections.Selecting stiff silkworm is put down, Return liver, lung channel because its nature and flavor is pungent, salty.It expels endogenous wind to relieve convulsion, resolving sputum dissipates Knot.For apoplexy facial paralysis, twitch, head is grant, larynx numbness, scrofula tuberculosis, rubella erysipelas.It is because of its nature and flavor to select uncaria Hardship, it is cool, enter liver, the heart channel of Hang-Shaoyin, there is The flat liver of heat-clearing, the function for the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. controls little Jing Epilepsy Chi Zong, adult's slight Hypertension, dizzy, mesh It is dizzy, married woman's sub- Epilepsy.Selecting gypsum is trembled with fear because of its property acrid-sweet flavor, enters lung, stomach, raw with having expelling pathogenic factors from muscles for clearing heat, the work(that relieving restlessness is quenched the thirst Can, it controls pyreticosis high fever and does not move back, vexed coma, delirious speech is gone mad, thirsty and dry pharynx, and lung heat asthma is anxious, heatstroke spontaneous perspiration, stomach fire headache, toothache, Heat toxin, which is stopped up, contains, and spot dermexanthesis, aphthae forges deposited myogenic sore, controls ulcer sores outside, bursts and does not withdraw, the burning hot wound of soup.Selection is worked as Return is to enter the heart, liver, the spleen channel because of its nature and flavor sweet, acrid, warm, have replenishing and activating blood, menstruction regulating and pain relieving, the function of moisturize laxation to control menstruation Uncomfortable, Amenorrhea abdominal pain , Disorder lump in the abdomen knots are poly-, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, and intestinal dryness difficulty is just, heavy after dysentery characterized by blood in the stool, ulcer sores, gold Sore, injury from falling down.Select Radix Paeoniae Alba be because of its nature and flavor picric acid, it is cool, enter liver, the spleen channel, there is nourishing blood and liver, cloudy receipts are held back in analgesic in delaying The function of sweat controls chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, irregular menstruation, uterine bleeding, under.Select river Rhizome of chuanxiong is to enter liver, gallbladder channel because its nature and flavor is acrid in flavour and warm in nature, there is promote breath and open depression, dispel pathogenic wind and remove dampness, the function of promoting blood circulation and stopping pain, controls air-cooled headache rotation It is dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores.It is because of its nature and flavor to select radix rehmanniae recen It is sweet, it trembles with fear, the thoughts of returning home, liver and kidney channel have clearing heat and cooling blood, yin-nourishing, the function of promoting the production of body fluid to control pyreticosis polydipsia, and yin asthenia generating intrinsic heat, hectic fever due to yin labor is hot, interior Heat is quenched one's thirst, and is spitted blood, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis.Selecting Fructus meliae toosendan is trembled with fear because its is bitter in taste, toxic, enters liver, stomach, small intestinl channel, has Wet down heat, clearing away the liver-fire, analgesic, the function of desinsection control pyretic epigastralgia, hypochondriac pain, colic, abdominal pain due to enterositosis.It is because of it to select radix scutellariae Taste bitter and cold enters cardiopulmonary, courage, large intestine channel, has and rush down excess fire, and except damp and hot, the function of arresting bleeding and miscarriage prevention controls high fever polydipsia, cough with lung heat. It is to tremble with fear because its is bitter in taste, enter lung, stomach, kidney channel, have nourishing yin and lessening fire, the function of moisturize laxation to control dysphoria with smothery sensation and quench one's thirst to select Cortex Phellodendri, Hectic fever due to yin labor heat, cough with lung heat, dry feces, difficult urination.It is to tremble with fear because its is bitter in taste, enter the heart, liver, lung, stomach to select cape jasmine Through, there are heat-clearing, purging intense heat, the function of cool blood to control pyreticosis restlessness of asrhenia type and insomnia, jaundice, gonorrhoea is quenched one's thirst, hot eyes, pharyngalgia, is spitted blood, bleeding from five sense organs or subcutaneous tissue, Bloody flux, hematuria, pathopyretic ulcer sprain swelling and pain.Select Fructus Forsythiae be because its is bitter in taste, it is cool, enter the heart, liver, gallbladder channel, there is heat-clearing, solve Poison, dissipating bind, the function of detumescence control warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.It is because of its property to select schizonepeta Taste is acrid in flavour and warm in nature, enters lung, Liver Channel, delivers, wind-dispelling, the function of regulating blood condition, fries charcoal hemostasis, and cure cold fever, headache, abscess of throat, in Air port is kept silent, and is spitted blood, and bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, postpartum anemic fainting, carbuncle swells, sore scabies, scrofula.Select it is windproof be because of its property acrid-sweet flavor, Temperature enters bladder, lung, the spleen channel, delivers, wind-dispelling, and victory is wet, and the function of analgesic is controlled and caught cold, headache, dizzy, Xiang Qiang, chill Arthritis with fixed pain caused by dampness, skeletal pain, four limbs contraction is anxious, lockjaw.Select Fructus Aurantii be because of its nature and flavor toil, it is cool, enter lung, spleen, large intestine channel, have broken Gas, row phlegm, the function of disperse accumulation, it is stagnant to control chest diaphragm phlegm, the feeling of stuffiness in chest, coerces swollen, dyspepsia, and gas is vomitted inverse, weight after diarrhea, rectal prolapse, and uterus is de- It hangs down.It is because its nature and flavor is sweet to select prepared rehmannia root, and tepor enters liver and kidney channel, there is enriching yin, the function of enriching blood, and it is few to control deficiency of Yin blood, waist and knee Impotence is weak, Cough osteopyrexia, and seminal emission, uterine bleeding, irregular menstruation is quenched one's thirst, number of urinating, deaf, blurred vision.It is because its nature and flavor is pungent to select moutan bark Hardship, it is cool, enter the heart, liver and kidney channel, there is heat-clearing, cool blood and blood, the function of dispersing blood stasis to control heat invading xuefen, macular eruption , Jing Epilepsy is spat, is defeated in battle, just Blood, hectic fever due to yin labor heat, Amenorrhea , Disorder lumps in the abdomen, large carbuncle flutter damage.It is to put down because of its property slightly sweet flavor, enter the heart, spleen, lung channel, have and ooze to select Poria cocos Wet Li Shui, beneficial spleen and stomach, the function of antitoxic heart-soothing and sedative control difficult urination, and oedema turgor, phlegm and retained fluid cough is inverse, the sound of vomiting of vomitting, diarrhea, pass out semen, leaching Turbid, palpitation with fear is forgetful.It is because its nature and flavor is sour to select Fructus Corni, and tepor enters liver and kidney channel, there is filling liver kidney, puckery vital essence, admittedly collapse Function controls soreness of waist and knee joint, and dizziness, tinnitus, impotence, seminal emission, frequent urination, liver cold of insufficiency type heat, incessant sweating due to debility, it is scattered that the heart shakes arteries and veins.It selects Rhizoma anemarrhenae is to tremble with fear because its is bitter in taste, enter lung, stomach, kidney channel, have nourishing yin and lessening fire, the function of moisturize laxation to control dysphoria with smothery sensation and quench one's thirst, hectic fever due to yin Labor heat, cough with lung heat, dry feces, difficult urination.

Specific implementation mode

The drug dose of instant component is also to be obtained by plenty of explorations of the inventor, and the dosage of each component is following heavy All tools have a better effect in amount range：

10-20 grams of radix bupleuri, 10-20 grams of the root of Dahurain angelica, 10-20 grams of cape jasmine, 10-20 grams of radix paeoniae rubra, 25-35 grams of waxgourd seed, dandelion 25-35 Gram, 15-25 grams of rhizoma alismatis, 5-15 grams of rough gentian, 10-14 grams of chrysanthemum, 10-14 grams of stiff silkworm, 15-25 grams of uncaria, 15-25 grams of gypsum, when Return 5-15 grams, 5-15 grams of Radix Paeoniae Alba, 5-15 grams of Rhizoma Chuanxiong, 10-14 grams of radix rehmanniae recen, 5-15 grams of Fructus meliae toosendan, 5-15 grams of radix scutellariae, Cortex Phellodendri 10- 14 grams, 10-20 grams of cape jasmine, 5-15 grams of Fructus Forsythiae, 5-15 grams of schizonepeta, windproof 5-15 grams, 5-15 grams of Fructus Aurantii, 10-20 grams of prepared rehmannia root is male 5-15 grams of the root bark of tree peony, 5-15 grams of Poria cocos, 5-15 grams of Fructus Corni, 5-15 grams of rhizoma anemarrhenae.

Preferably：

15 grams of radix bupleuri, 15 grams of the root of Dahurain angelica, 15 grams of cape jasmine, 15 grams of radix paeoniae rubra, 30 grams of waxgourd seed, 30 grams of dandelion, 20 grams of rhizoma alismatis, rough gentian 10 Gram, 12 grams of chrysanthemum, 12 grams of stiff silkworm, 20 grams of uncaria, 20 grams of gypsum, 10 grams of Radix Angelicae Sinensis, 10 grams of Radix Paeoniae Alba, 10 grams of Rhizoma Chuanxiong, 12 grams of radix rehmanniae recen, 10 grams of Fructus meliae toosendan, 10 grams of radix scutellariae, 12 grams of Cortex Phellodendri, 15 grams of cape jasmine, 10 grams of Fructus Forsythiae, 10 grams of schizonepeta, windproof 10 grams, 10 grams of Fructus Aurantii is ripe 15 grams of glutinous rehmannia, 10 grams of moutan bark, 10 grams of Poria cocos, 10 grams of Fructus Corni, 10 grams of rhizoma anemarrhenae.

The preparation method of drug of the present invention is as follows

One, it stocks up

1, radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulls out, is sliced after moisturizing, dries immediately in time；

2, the root of Dahurain angelica：Net impurity is picked, is eluted with water, is impregnated, is pulled out and moisturize, when slightly shining to crust without soapy feeling, then after bored profit, slice It is dry；

3, cape jasmine：Grey bits are weeded out, impurity is picked, pulverize sieving or cut off both ends；

4, radix paeoniae rubra：Crude drug is taken, impurity is removed, size stepping is cleaned, moisturized, shave, dry, weeds out clast；

5, waxgourd seed：Net impurity is picked, the used time smashs to pieces, or with yellow-white is fried with slow fire, and sets dry place；

6, dandelion：Impurity is picked, soil is cleaned, segment is dried；

7, rhizoma alismatis：Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, and solarization is cool, and bored profit is cut to uniform humidity inside and outside Piece dries；

8, rough gentian：Impurity is picked, residual stem is removed, is cleaned, is moisturized rear segment, dry；

9, chrysanthemum：Pick net leaf stalk, anthocaulus and spare impurity；

10, stiff silkworm：Crude drug is taken, residual silk, impurity are removed；

11, uncaria：Old stalk, impurity are picked, cleans, dries；

12, gypsum：Miscellaneous stone is removed, soil is cleaned, is broken into fritter；

13, Radix Angelicae Sinensis：Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries；

14, Radix Paeoniae Alba：Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit to uniform humidity inside and outside, Slice, it is dry；

15, Rhizoma Chuanxiong：Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, and is sliced after bored profit, dry；

16, radix rehmanniae recen：Crude drug is taken, impurity is removed, is cleaned, is slightly moistened, cut sheet, it is dry, weed out clast；

17, Fructus meliae toosendan：Impurity is picked, is cleaned, drying or is split into two halves at grating；

18, radix scutellariae：Impurity is picked, residual stem is removed, is infiltrated with cold water or sets slightly to soak in boiling water and pulled out, slice dries after moisturizing, and notes Meaning avoids exposure excessively rubescent；

19, Cortex Phellodendri：Impurity is picked, is eluted with water, is pulled out, is moisturized, slice or chopping are dried；

20, cape jasmine：Grey bits are weeded out, impurity is picked, pulverize sieving or cut off both ends；

21, Fructus Forsythiae：Net impurity is picked, is rubbed open, discarding stalk is removed；

22, schizonepeta：Net impurity is picked, is slightly steeped with water, is pulled segment out, dry；

23, windproof：Residual stem is removed, is soaked in water, is pulled out, slice is moisturized, dries；

24, Fructus Aurantii：Flesh, core are removed, edulcoration is slightly soaked, pulled out, softens, and it is degree that can pinch doubling with hand, and slice dries；

25, prepared rehmannia root：Select clean prepared rehmannia root；

26, moutan bark：Impurity is picked, core is removed, cleans, moisturizes, is sliced, dries；

27, Poria cocos：It is soaked in water, cleans and pull out, after bored, slice dries；

28, Fructus Corni：It cleans, removes removal core and impurity, dry；

29, rhizoma anemarrhenae：Net impurity is picked, is hit and is washed with water, is pulled out, is softened, slice dries.

Two, it prepares

1, by the radix bupleuri of the weight, the root of Dahurain angelica, cape jasmine, radix paeoniae rubra, waxgourd seed, dandelion, rhizoma alismatis, rough gentian, chrysanthemum, stiff silkworm, uncaria, Gypsum, Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong, radix rehmanniae recen, Fructus meliae toosendan, radix scutellariae, Cortex Phellodendri, cape jasmine, Fructus Forsythiae, schizonepeta, windproof, Fructus Aurantii, prepared rehmannia root, Moutan bark, Poria cocos, Fructus Corni, rhizoma anemarrhenae are put into decocting container, add 8 times of amounts of water, after impregnating 80 minutes, high heat decoction boiling, then With being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is poured into container；

2, the dregs of a decoction of filtering are added into 6 times of amounts of water, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；

3, it decoction liquor will be mixed evenly twice, and be divided into 4 doses and take.

The root of Dahurain angelica has wind-dispelling in prescription, and the function of eliminating dampness, detumescence, analgesic is monarch drug in a prescription；Radix paeoniae rubra has clearing heat and cooling blood, removing blood stasis and analgesics Function；Fructus Forsythiae has heat-clearing, removing toxic substances, dissipating bind, the function of detumescence, and the two is ministerial drug, and three taste medicines are played and dispelled pathogenic wind and remove dampness jointly, and detumescence stops Bitterly, clearing heat and cooling blood, the effect of removing blood stasis and analgesics, treatment otitis media suppurative effect is comprehensive, and to dispel pathogenic wind and remove dampness, swelling and pain relieving, clearly It can effect a permanent cure based on hot cool blood, moutan bark has heat-clearing, cool blood and blood, and the function of dispersing blood stasis is adjutant, and rhizoma anemarrhenae has nourishing yin and lessening fire, moisturizes The function of laxation is to make medicine, and all medicines are to take stopgap measures with being left.

Drug of the present invention, which has, to dispel pathogenic wind and remove dampness, swelling and pain relieving, clearing heat and cooling blood, and the function of removing blood stasis and analgesics is suppurated for treating Property tympanitis, short treating period, quick, non-relapse after healing.

Carry out the advantageous effect of the present invention is further explained the drug below by way of test example, these test examples include this hair The animal toxicity test report of bright drug and clinical observation on the therapeutic effect data.

The animal toxicity test of [test example 1] drug of the present invention is reported：

Rabbit 30, male and female dual-purpose, 2.0-2.5kg of weight is taken to be divided to two groups, every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, normal amount 10ml/kg, and administering mode gives for administration by gavage Medicine even served 7 days twice daily, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and drug is without bad Toxic side effect.

The clinical observation on the therapeutic effect of [test example 2] drug of the present invention

1, general information

Accept otitis media suppurative out-patient totally 33 for medical treatment.

2, diagnostic criteria

Classical symptom is onset early stage, and tympanal flaccid part is congested, beats the blood vessel of the visible radial expansion of bone handle and tense part of tympanic membrane periphery. Followed by the hyperemia of eardrum diffusivity, swelling, outside bulging, normal mark are difficult to recognize, partially visible little Huang points.As inflammation cannot obtain To timely control, that is, develop into the tympanic membrane perforation.The general beginning of perforation is very small, after being not easy it is clear that thoroughly plot external ear is led, just sees and wears There is beating bright spot at hole, actually fester is gushed out from this.Necrotic type person eardrum is rapid molten routed, forms large perforation.

3, therapy

Above-mentioned medicament is selected, is taken to patient, each taking 1 dose, early daily, evening respectively takes 1 time, 10 days as a treatment course, continuously It takes 2 course for the treatment of.

4, efficacy assessment standard

It is effective：Otitis media suppurative symptom disappears, and restores normal, recovery from illness；

It improves：The symptoms were significantly improved for otitis media suppurative, and congested, swelling symptom mitigates, and gradually restores；

In vain：Improvement standard person is not achieved.

5, treatment results（It see the table below）

In above-mentioned treatment, with drug therapy otitis media suppurative patient 33 of the present invention, as a result effective 27, obvious effective rate is 81.8%, it improves 4, improvement rate 12.1%, invalid 2, total effective rate 93.9%.

Claims (3)

1. a kind of drug for treating otitis media suppurative, it is characterised in that：It is made of the bulk pharmaceutical chemicals in following weight range：

10-20 grams of radix bupleuri, 10-20 grams of the root of Dahurain angelica, 10-20 grams of cape jasmine, 10-20 grams of radix paeoniae rubra, 25-35 grams of waxgourd seed, dandelion 25-35 Gram, 15-25 grams of rhizoma alismatis, 5-15 grams of rough gentian, 10-14 grams of chrysanthemum, 10-14 grams of stiff silkworm, 15-25 grams of uncaria, 15-25 grams of gypsum, when Return 5-15 grams, 5-15 grams of Radix Paeoniae Alba, 5-15 grams of Rhizoma Chuanxiong, 10-14 grams of radix rehmanniae recen, 5-15 grams of Fructus meliae toosendan, 5-15 grams of radix scutellariae, Cortex Phellodendri 10- 14 grams, 10-20 grams of cape jasmine, 5-15 grams of Fructus Forsythiae, 5-15 grams of schizonepeta, windproof 5-15 grams, 5-15 grams of Fructus Aurantii, 10-20 grams of prepared rehmannia root is male 5-15 grams of the root bark of tree peony, 5-15 grams of Poria cocos, 5-15 grams of Fructus Corni, 5-15 grams of rhizoma anemarrhenae.

2. drug according to claim 1, wherein the dosage of each bulk pharmaceutical chemicals is：

15 grams of radix bupleuri, 15 grams of the root of Dahurain angelica, 15 grams of cape jasmine, 15 grams of radix paeoniae rubra, 30 grams of waxgourd seed, 30 grams of dandelion, 20 grams of rhizoma alismatis, rough gentian 10 Gram, 12 grams of chrysanthemum, 12 grams of stiff silkworm, 20 grams of uncaria, 20 grams of gypsum, 10 grams of Radix Angelicae Sinensis, 10 grams of Radix Paeoniae Alba, 10 grams of Rhizoma Chuanxiong, 12 grams of radix rehmanniae recen, 10 grams of Fructus meliae toosendan, 10 grams of radix scutellariae, 12 grams of Cortex Phellodendri, 15 grams of cape jasmine, 10 grams of Fructus Forsythiae, 10 grams of schizonepeta, windproof 10 grams, 10 grams of Fructus Aurantii is ripe 15 grams of glutinous rehmannia, 10 grams of moutan bark, 10 grams of Poria cocos, 10 grams of Fructus Corni, 10 grams of rhizoma anemarrhenae.

3. the preparation method of drug according to claim 1 or claim 2, it includes the following steps：

（One）Stock

（1）Radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulls out, is sliced after moisturizing, dries immediately in time；

（2）The root of Dahurain angelica：Net impurity is picked, is eluted with water, is impregnated, is pulled out and moisturize, when slightly shining to crust without soapy feeling, then after bored profit, cut Piece is dried；

（3）Cape jasmine：Grey bits are weeded out, impurity is picked, pulverize sieving or cut off both ends；

（4）Radix paeoniae rubra：Crude drug is taken, impurity is removed, size stepping is cleaned, moisturized, shave, dry, weeds out clast；

（5）Waxgourd seed：Net impurity is picked, the used time smashs to pieces, or with yellow-white is fried with slow fire, and sets dry place；

（6）Dandelion：Impurity is picked, soil is cleaned, segment is dried；

（7）Rhizoma alismatis：Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, shines cool, bored profit to uniform humidity inside and outside, Slice, is dried；

（8）Rough gentian：Impurity is picked, residual stem is removed, is cleaned, is moisturized rear segment, dry；

（9）Chrysanthemum：Pick net leaf stalk, anthocaulus and spare impurity；

（10）Stiff silkworm：Crude drug is taken, residual silk, impurity are removed；

（11）Uncaria：Old stalk, impurity are picked, cleans, dries；

（12）Gypsum：Miscellaneous stone is removed, soil is cleaned, is broken into fritter；

（13）Radix Angelicae Sinensis：Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries；

（14）Radix Paeoniae Alba：Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit to uniform humidity inside and outside, Slice, it is dry；

（15）Rhizoma Chuanxiong：Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, and is sliced after bored profit, dry；

（16）Radix rehmanniae recen：Crude drug is taken, impurity is removed, is cleaned, is slightly moistened, cut sheet, it is dry, weed out clast；

（17）Fructus meliae toosendan：Impurity is picked, is cleaned, drying or is split into two halves at grating；

（18）Radix scutellariae：Impurity is picked, residual stem is removed, is infiltrated with cold water or sets slightly to soak in boiling water and pulled out, slice dries after moisturizing, and notes Meaning avoids exposure excessively rubescent；

（19）Cortex Phellodendri：Impurity is picked, is eluted with water, is pulled out, is moisturized, slice or chopping are dried；

（20）Cape jasmine：Grey bits are weeded out, impurity is picked, pulverize sieving or cut off both ends；

（21）Fructus Forsythiae：Net impurity is picked, is rubbed open, discarding stalk is removed；

（22）Schizonepeta：Net impurity is picked, is slightly steeped with water, is pulled segment out, dry；

（23）It is windproof：Residual stem is removed, is soaked in water, is pulled out, slice is moisturized, dries；

（24）Fructus Aurantii：Flesh, core are removed, edulcoration is slightly soaked, pulled out, softens, and it is degree that can pinch doubling with hand, and slice dries；

（25）Prepared rehmannia root：Select clean prepared rehmannia root；

（26）Moutan bark：Impurity is picked, core is removed, cleans, moisturizes, is sliced, dries；

（27）Poria cocos：It is soaked in water, cleans and pull out, after bored, slice dries；

（28）Fructus Corni：It cleans, removes removal core and impurity, dry；

（29）Rhizoma anemarrhenae：Net impurity is picked, is hit and is washed with water, is pulled out, is softened, slice dries；

（Two）It prepares

（1）By the radix bupleuri of the weight, the root of Dahurain angelica, cape jasmine, radix paeoniae rubra, waxgourd seed, dandelion, rhizoma alismatis, rough gentian, chrysanthemum, stiff silkworm, hook Rattan, gypsum, Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong, radix rehmanniae recen, Fructus meliae toosendan, radix scutellariae, Cortex Phellodendri, cape jasmine, Fructus Forsythiae, schizonepeta, windproof, Fructus Aurantii, radix rehmanniae preparata Huang, moutan bark, Poria cocos, Fructus Corni, rhizoma anemarrhenae are put into decocting container, add 8 times of amounts of water, after impregnating 80 minutes, high heat decoction boiling, Again with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is poured into container；

（2）The dregs of a decoction of filtering are added into 6 times of amounts of water, are boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；

（3）It decoction liquor will be mixed evenly twice, and be divided into 4 doses and take.