CN108272954A - A kind of drug and preparation method thereof for treating acute mastitis - Google Patents

A kind of drug and preparation method thereof for treating acute mastitis Download PDF

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CN108272954A
CN108272954A CN201810370162.2A CN201810370162A CN108272954A CN 108272954 A CN108272954 A CN 108272954A CN 201810370162 A CN201810370162 A CN 201810370162A CN 108272954 A CN108272954 A CN 108272954A
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radix
impurity
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root
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张明夫
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/35Caprifoliaceae (Honeysuckle family)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract

The invention discloses a kind of drugs and preparation method thereof for treating acute mastitis, it is prepared according to a certain weight ratio by the seed of cowherb, Radix Rhapontici seu Radix Echinopsis, the stem pith of the rice-paper plant, honeysuckle, Fructus Forsythiae, radix paeoniae rubra, moutan bark, tangerine leaf, dandelion, deer horn, Fructus Liquidambaris, great burdock achene, bulbus fritillariae cirrhosae, root of Chinese trichosanthes, Radix Angelicae Sinensis, the root of Dahurain angelica, Radix Glycyrrhizae, Rhizoma Chuanxiong, Radix Astragali, green peel, campanulaceae, drug of the present invention has promoting circulation of blood promoting menstruation, expedite the emergence of lower breast, healing up sore and subduing swelling, it is clearing heat and detoxicating, the function of resolving sputum detumescence, acute mastitis is quick, good effect for treating, and does not recur.

Description

A kind of drug and preparation method thereof for treating acute mastitis
Technical field
The present invention relates to a kind of drugs and preparation method thereof for treating acute mastitis, belong to the field of Chinese medicines.
Background technology
For acute mastitis with breast congestion and swelling pain, milk discharge is unsmooth, so that acute festering type disease of the knot purulence at carbuncle.It is mainly in production The puerpera of lactation afterwards, especially primipara are more common.It is commonly called as mastitis.According to the difference of occurrent time, and there are several titles:Hair It is born in nursing period person, claims postpartum mastitis;Betide period of pregnancy person, name acute mastitis during pregnancy;Survivor is sent out in non-lactation period and non-period of pregnancy, Name non-lactation period acute mastitis.The acute purulent mammitis of modern medicine belongs to acute mastitis scope.Since western medicine side effect is big, because There are great demands to the Chinese medicine of effectively treating acute mastitis by this people, up to now, it has not been found that about the present invention's Related report.
Invention content
Repeatedly verification of the present inventor according to research and the clinical test of theory of traditional Chinese medical science has finally found effectively treatment acute mastitis Drug, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine compositions of effective treatment acute mastitis.
Another aim of the present invention is to provide the preparation methods of the Chinese medicine composition.
Drug of the present invention is the selection seed of cowherb, Radix Rhapontici seu Radix Echinopsis, the stem pith of the rice-paper plant, honeysuckle, Fructus Forsythiae, radix paeoniae rubra, moutan bark, tangerine leaf, Pu Gong English, deer horn, Fructus Liquidambaris, great burdock achene, bulbus fritillariae cirrhosae, root of Chinese trichosanthes, Radix Angelicae Sinensis, the root of Dahurain angelica, Radix Glycyrrhizae, Rhizoma Chuanxiong, Radix Astragali, green peel, campanulaceae, Snakegourd Fruit, Radix bupleuri, Radix Paeoniae Alba, cassia twig, the root of three-nerved spicebush are combined preparation, make each efficacy of drugs generate synergistic effect these pharmaceutical compositions, from And it can effectively treat acute mastitis.It is to enter liver, stomach because its is bitter in taste flat, have promoting circulation of blood promoting menstruation, expedite the emergence of wherein to select the seed of cowherb Lower breast, the function of healing up sore and subduing swelling control women's Amenorrhea, alactation, difficult labour, blood strangury, carbuncle swells, metal-inflicted wound bleeding.Select Radix Rhapontici seu Radix Echinopsis be because It is bitter in taste salty-cold for its, enter stomach, large intestine channel, there is clearing heat and detoxicating, the function of lower breast, controls the swollen pain of breast, alactation, heat toxin blood Dysentery, arthralgia.Select the stem pith of the rice-paper plant be because of its property slightly sweet flavor, it is cool, enter lung, stomach, there is a purging the lung of pathogenic fire, diuresis, the function of lower milk, Control difficult urination, gonorrhoea, oedema, puerpera's alactation, blurred vision, nasal obstruction.Select honeysuckle be because its nature and flavor it is sweet, tremble with fear, enter lung, Stomach has heat-clearing, the function of removing toxic substances to control warm disease heating, toxic-heat and blood stasis, large carbuncle, pyogenic infections, scrofula, anal fistula.Select Fructus Forsythiae be because Its is bitter in taste, cool, enters the heart, liver, gallbladder channel, there is heat-clearing, removing toxic substances, dissipating bind, and the function of detumescence controls warm, erysipelas, macula, and large carbuncle swells Poison, scrofula, urine leaching closes.Selecting radix paeoniae rubra is slightly cold, return liver warp has clearing heat and cooling blood, the work(of removing blood stasis and analgesics because its is bitter in taste Can, it controls epidemic heat syndrome and goes mad, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, closed dysmenorrhea , Epilepsy lump in the abdomen abdominal pain, injury from falling down, carbuncle swells sore. Selecting moutan bark is worked hard because of its nature and flavor, cool, enters the heart, liver and kidney channel, has heat-clearing, cool blood and blood, the function of dispersing blood stasis to control heat and enter Blood system, macular eruption , Jing Epilepsy, spits, is defeated in battle, has blood in stool, and hectic fever due to yin labor heat, Amenorrhea , Disorder lumps in the abdomen, large carbuncle flutters damage.It is because its is bitter in taste to select tangerine leaf It is pungent, it puts down, enters liver channel of foot-Jueyin qi leel, there is soothing the liver, promoting the circulation of qi, resolving sputum, the function for poison of subsiding a swelling to control hypochondriac pain, acute mastitis, lung carbuncle, cough, chest Diaphragm feeling of fullness, hernia.It is to tremble with fear because of its nature and flavor bitter sweet, enter liver, stomach, there is clearing heat and detoxicating, the work(of diuresis dissipating bind to select dandelion Can, control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, acute tonsillitis is acute Bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections.It is because its nature and flavor is salty to select deer horn, and temperature enters liver and kidney channel, there is row Blood, detumescence, the function of kidney-nourishing control sore swollen toxin, and hemostasis is had a pain, consumptive disease internal injury, lumbar vertebrae pain.It is because of its property to select Fructus Liquidambaris Bitter is flat, and current 12 warp has dispelling wind and removing obstruction in the meridians, the function of promoting urination and removing dampness to harness the river swollen, turgor, Amenorrhea, breast is few, brothers' contraction.Choosing With great burdock achene worked hard because of its nature and flavor, it is cool, enter lung, stomach, there is dispelling wind and heat from the body, facilitaing lung promoting eruption, the function of subdhing swelling and detoxicating to control wind Heat cough, abscess of throat, macula is impermeable, and rubella is had an itch, carbuncle sore tumefacting virus.Select bulbus fritillariae cirrhosae be because of its nature and flavor bitter sweet, it is cool, enter lung Through having moistening lung dissipating bind, the function for resolving sputum of only coughing controls cough due to consumptive disease, spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung carbuncle, goiter and tumor, scrofula Scrofula, larynx numbness, acute mastitis.It is to enter lung, stomach because its nature and flavor sweetness and bitterness acid, cool, have and promote the production of body fluid, quench the thirst to select root of Chinese trichosanthes, and fall fire is moisturized, Apocenosis, the function of detumescence, it is thirsty to control pyreticosis, quenches one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle swells, hemorrhoid complicated by anal fistula.It is because of its nature and flavor to select Radix Angelicae Sinensis Sweet, acrid, warm enters the heart, liver, the spleen channel, there is a benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, the function of moisturize laxation, controls irregular menstruation, Amenorrhea abdominal pain, Disorder lump in the abdomen knots are poly-, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, and intestinal dryness difficulty is just, heavy after dysentery characterized by blood in the stool, ulcer sores, metal-inflicted wound, injury from falling down.Choosing It is to enter lung, spleen, stomach because its nature and flavor is acrid in flavour and warm in nature with the root of Dahurain angelica, has wind-dispelling, eliminating dampness to subside a swelling, the function of analgesic controls headache, eyebrow rib Ostalgia, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin itchy, mange.Select Radix Glycyrrhizae be because For its nature and flavor sweet and neutral, enter spleen, stomach, lung channel, has and middle emergency, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription;Toast is used, and taste food is controlled It is few, abdominal pain loose stool, overstrain fever, consumptive lung disease cough, palpitaition , Jing Epilepsy;It is raw to use, control abscess of throat, peptic ulcer, carbuncle subcutaneous ulcer sore, Antidote poison and food poisoning.It is to enter liver, gallbladder channel because its nature and flavor is acrid in flavour and warm in nature, there is promote breath and open depression, dispel pathogenic wind and remove dampness to select Rhizoma Chuanxiong, is invigorated blood circulation The function of analgesic controls air-cooled headache rotation and swoons, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores. It is because its nature and flavor is sweet to select Radix Astragali, and tepor enters lung, the spleen channel, raw with having invigorating qi for consolidating superficies, inducing diuresis for removing edema, eliminating toxic, the work(of myogenic Can, control spontaneous perspiration, night sweat, blood-arthralgia, edema, un-festering of ulcer or prolonged fester before gathering;The toast function of having bowl spares benefit, controls internal injury overstrain, spleen deficiency Diarrhea, rectal prolapse, deficiency of vital energy blood is de-, collapses band and the disease of all laboured breathing deficiency of blood.It is the tepor because of its nature and flavor toil to select green peel, enter liver, Gallbladder channel has soothing the liver relieving stagnant Qi, the function of dissipating bind dissolving phlegm to control chest side of body gastral cavity pain, and hernia, dyspepsia, breast is swollen, newborn core, chronic malaria addiction block.Choosing It is to put down because of its nature and flavor toil, enter lung, stomach, have open the inhibited lung-energy, the function of eliminating the phlegm apocenosis to control exogenous cough, throat with campanulaceae Swelling and pain, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery abdominal pain.It is sweet, slight bitter because of its nature and flavor to select Snakegourd Fruit, is trembled with fear, return lung, stomach, large intestine Through, there are clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, the function of moisturize laxation to control cough with lung heat, the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, Acute mastitis, acute appendicitis, constipation.Select radix bupleuri be because its is bitter in taste, it is cool, enter liver, gallbladder channel, have in inducing diaphoresis, it is soothing the liver, rising Yang Function controls fevers and chills alternate, and fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower profit rectal prolapse, irregular menstruation, metroptosis.Choosing With Radix Paeoniae Alba be because of its nature and flavor picric acid, it is cool, enter liver, the spleen channel, there is nourishing blood and liver, analgesic in delaying holds back the cloudy function of receiving sweat, controls chest and abdomen Pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, irregular menstruation, uterine bleeding, under.It is because its nature and flavor is pungent to select cassia twig Sweet, warm enters bladder, the heart, lung channel, has sweating expelling pathogenic factors from muscles and skin, the function of warming meridians and promoting circulation of qi to control exterior syndrome due to wind-cold, shoulder carries on the back podomere ache, obstruction of qi in the chest phlegm Drink, Jing Bi Disorder lumps in the abdomen.It is to enter spleen, lung, kidney, bladder warp because its nature and flavor is acrid in flavour and warm in nature, have pleasant, open strongly fragrant, cold dispelling to select the root of three-nerved spicebush, is relieved pain Function, control circulation of vital energy in the wrong direction chest and abdomen swelling and pain, place food is discontented, regurgitation and emesis, cold hernia, tinea pedis, frequent urination.
Specific implementation mode
The drug dose of instant component is also to be obtained by plenty of explorations of the inventor, and the dosage of each component is following heavy All tools have a better effect in amount range:
25-35 grams of the seed of cowherb, 5-15 grams of Radix Rhapontici seu Radix Echinopsis, 5-15 grams of the stem pith of the rice-paper plant, 10-20 grams of honeysuckle, 10-20 grams of Fructus Forsythiae, radix paeoniae rubra 5-15 Gram, 5-15 grams of moutan bark, 5-15 grams of tangerine leaf, 25-35 grams of dandelion, 5-15 grams of deer horn, 5-15 grams of Fructus Liquidambaris, great burdock achene 5-15 Gram, 5-15 grams of bulbus fritillariae cirrhosae, 5-15 grams of root of Chinese trichosanthes, 5-15 grams of Radix Angelicae Sinensis, 5-15 grams of the root of Dahurain angelica, 6-10 grams of Radix Glycyrrhizae, 5-15 grams of Rhizoma Chuanxiong, Radix Astragali 5-15 grams, 5-15 grams of green peel, 5-15 grams of campanulaceae, 5-15 grams of Snakegourd Fruit, 5-15 grams of radix bupleuri, 5-15 grams of Radix Paeoniae Alba, 4-8 grams of cassia twig, the root of three-nerved spicebush 3-5 grams.
Preferably:
30 grams of the seed of cowherb, 10 grams of Radix Rhapontici seu Radix Echinopsis, 10 grams of the stem pith of the rice-paper plant, 15 grams of honeysuckle, 15 grams of Fructus Forsythiae, 10 grams of radix paeoniae rubra, 10 grams of moutan bark, tangerine 10 grams of leaf, 30 grams of dandelion, 10 grams of deer horn, 10 grams of Fructus Liquidambaris, 10 grams of great burdock achene, 10 grams of bulbus fritillariae cirrhosae, 10 grams of root of Chinese trichosanthes, Radix Angelicae Sinensis 10 Gram, 10 grams of the root of Dahurain angelica, 8 grams of Radix Glycyrrhizae, 10 grams of Rhizoma Chuanxiong, 10 grams of Radix Astragali, 10 grams of green peel, 10 grams of campanulaceae, 10 grams of Snakegourd Fruit, 10 grams of radix bupleuri, in vain 10 grams of Chinese herbaceous peony, 6 grams of cassia twig, 3 grams of the root of three-nerved spicebush.
The preparation method of drug of the present invention is as follows
One, it stocks up
1, the seed of cowherb:It winnows with a dustpan net impurity, sets in pot, taken out, cooled with the when of popping white flower six, seventy percent is fried with slow fire;
2, Radix Rhapontici seu Radix Echinopsis:Net impurity is picked, unhairing is cleaned, moisturized, and is sliced, is dried;
3, the stem pith of the rice-paper plant:Impurity is picked, is sliced;
4, honeysuckle:Silt is weeded out, net impurity is picked;
5, Fructus Forsythiae:Net impurity is picked, is rubbed open, discarding stalk is removed;
6, radix paeoniae rubra:Crude drug is taken, impurity is removed, size stepping is cleaned, moisturized, shave, dry, weeds out clast;
7, moutan bark:Impurity is picked, core is removed, cleans, moisturizes, is sliced, dries;
8, tangerine leaf:Net impurity is picked, is dried;
9, dandelion:Impurity is picked, soil is cleaned, segment is dried;
10, harts horn carbon:A pound piece is taken to be ground into fine powder;
11, Fructus Liquidambaris:Impurity is removed, cleans, dries;
12, great burdock achene:Impurity is picked, spare is weeded out;
13, bulbus fritillariae cirrhosae:Impurity is picked, is slightly steeped, is pulled out with water, bored profit is peelled off the heart, dried;
14, root of Chinese trichosanthes:Impurity is picked, size block is separated, saturating with bubble about sixty percent, pulls out, and bored profit is cut to uniform humidity inside and outside Piece dries;
15, Radix Angelicae Sinensis:Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries;
16, the root of Dahurain angelica:Net impurity is picked, is eluted with water, is impregnated, is pulled out and moisturize, when slightly shining to crust without soapy feeling, then after bored profit, cut Piece is dried;
17, Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, moisturize slice, dry;
18, Rhizoma Chuanxiong:Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, and is sliced after bored profit, dry;
19, Radix Astragali:Net impurity is picked, remaining head and hollow larger root is removed, is soaked in water, pulls out, cut in time after moisturizing Piece dries;
20, green peel:Net impurity is picked, is soaked in water, is pulled out, is moisturized, is sliced, dries;
21, campanulaceae:Net impurity is picked, removing LU is removed, cleans and pulls out, be sliced, dry after moisturizing;
22, Snakegourd Fruit:Crude drug is taken, impurity and carpopodium are removed, is cleaned, is flattened, chopping or fritter are dry;
23, radix bupleuri:Impurity is picked, residual stem is removed, silt is cleaned, pulls out, is sliced after moisturizing, dries immediately in time;
24, Radix Paeoniae Alba:Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit to uniform humidity inside and outside, Slice, it is dry;
25, cassia twig:It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit;
26, the root of three-nerved spicebush:Impurity is picked, size bar is separated, it is saturating with bubble, paid attention to changing water according to season, prevent smelly, pulled out cut in time Piece weeds out grey bits.
Two, it prepares
1, by the seed of cowherb of the weight, Radix Rhapontici seu Radix Echinopsis, the stem pith of the rice-paper plant, honeysuckle, Fructus Forsythiae, radix paeoniae rubra, moutan bark, tangerine leaf, dandelion, deer Angle, Fructus Liquidambaris, great burdock achene, bulbus fritillariae cirrhosae, root of Chinese trichosanthes, Radix Angelicae Sinensis, the root of Dahurain angelica, Radix Glycyrrhizae, Rhizoma Chuanxiong, Radix Astragali, green peel, campanulaceae, Snakegourd Fruit, radix bupleuri, Radix Paeoniae Alba, cassia twig, the root of three-nerved spicebush are put into decocting container, add 8 times of water amount, after impregnating 90 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is poured into container;
2, the dregs of a decoction of filtering are added into 6 times of amounts of water, boiled by intense fire, then with being cooked by slow fire 30 minutes, filter to obtain second of decoction liquor;
3, it decoction liquor will be mixed evenly twice, and be divided into 3 doses and take.
The seed of cowherb has promoting circulation of blood promoting menstruation in prescription, expedites the emergence of lower breast, the function of healing up sore and subduing swelling is monarch drug in a prescription;Radix Rhapontici seu Radix Echinopsis has heat-clearing solution Poison, the function of lower breast;It is ministerial drug that Fructus Forsythiae, which has clearing heat and detoxicating, the function of mass dissipating and swelling eliminating, the two, and it is logical that three taste medicines play promoting circulation of blood jointly Through expediting the emergence of lower breast, healing up sore and subduing swelling is clearing heat and detoxicating, the effect of mass dissipating and swelling eliminating, and treatment acute mastitis effect is comprehensive, and with promoting circulation of blood promoting menstruation, urges Give birth to breast, healing up sore and subduing swelling, it is clearing heat and detoxicating based on can effect a permanent cure, tangerine leaf has soothing the liver, promoting the circulation of qi, and the function of resolving sputum, detumescence is adjutant, Pu Gong English has clearing heat and detoxicating, and the function of diuresis dissipating bind is to make medicine, and all medicines are to take stopgap measures with being left.
Drug of the present invention has promoting circulation of blood promoting menstruation, expedites the emergence of lower breast, and healing up sore and subduing swelling is clearing heat and detoxicating, and the function of resolving sputum detumescence is used for Treat acute mastitis, short treating period, quick, non-relapse after healing.
Carry out the advantageous effect of the present invention is further explained the drug below by way of test example, these test examples include this hair The animal toxicity test report of bright drug and clinical observation on the therapeutic effect data.
The animal toxicity test of [test example 1] drug of the present invention is reported:
Rabbit 30, male and female dual-purpose, 2.0-2.5kg of weight is taken to be divided to two groups, every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, normal amount 10ml/kg, and administering mode gives for administration by gavage Medicine even served 7 days twice daily, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and drug is without bad Toxic side effect.
The clinical observation on the therapeutic effect of [test example 2] drug of the present invention
1, general information
Accept acute mastitis out-patient totally 47 for medical treatment.
2, diagnostic criteria
Classical symptom is breast portion caking, swelling pain, is generated heat with whole body, and purulence goes out stiff after bursting.It is not yet full to be mainly in postpartum The nursing women of the moon, it is especially common with cracked nipple or the stagnant person of the milk stasis of blood.
3, therapy
Above-mentioned medicament is selected, is taken to patient, each taking 1 dose, early daily, evening respectively takes 1 time, 10 days as a treatment course, continuously It takes 4 course for the treatment of.
4, efficacy assessment standard
It is effective:Acute mastitis symptom disappears, and restores normal, recovery from illness;
It improves:The symptoms were significantly improved for acute mastitis, and caking reduces, and pain relief, nipple gradually restores normal;
In vain:Improvement standard person is not achieved.
5, treatment results(It see the table below)
In above-mentioned treatment, with drug therapy acute mastitis patient 47 of the present invention, as a result effective 39, obvious effective rate 83% improves 5 Example, improvement rate 10.6%, invalid 3, total effective rate 93.6%.

Claims (3)

1. a kind of drug for treating acute mastitis, it is characterised in that:It is made of the bulk pharmaceutical chemicals in following weight range:
25-35 grams of the seed of cowherb, 5-15 grams of Radix Rhapontici seu Radix Echinopsis, 5-15 grams of the stem pith of the rice-paper plant, 10-20 grams of honeysuckle, 10-20 grams of Fructus Forsythiae, radix paeoniae rubra 5-15 Gram, 5-15 grams of moutan bark, 5-15 grams of tangerine leaf, 25-35 grams of dandelion, 5-15 grams of deer horn, 5-15 grams of Fructus Liquidambaris, great burdock achene 5-15 Gram, 5-15 grams of bulbus fritillariae cirrhosae, 5-15 grams of root of Chinese trichosanthes, 5-15 grams of Radix Angelicae Sinensis, 5-15 grams of the root of Dahurain angelica, 6-10 grams of Radix Glycyrrhizae, 5-15 grams of Rhizoma Chuanxiong, Radix Astragali 5-15 grams, 5-15 grams of green peel, 5-15 grams of campanulaceae, 5-15 grams of Snakegourd Fruit, 5-15 grams of radix bupleuri, 5-15 grams of Radix Paeoniae Alba, 4-8 grams of cassia twig, the root of three-nerved spicebush 3-5 grams.
2. drug according to claim 1, wherein the dosage of each bulk pharmaceutical chemicals is:
30 grams of the seed of cowherb, 10 grams of Radix Rhapontici seu Radix Echinopsis, 10 grams of the stem pith of the rice-paper plant, 15 grams of honeysuckle, 15 grams of Fructus Forsythiae, 10 grams of radix paeoniae rubra, 10 grams of moutan bark, tangerine 10 grams of leaf, 30 grams of dandelion, 10 grams of deer horn, 10 grams of Fructus Liquidambaris, 10 grams of great burdock achene, 10 grams of bulbus fritillariae cirrhosae, 10 grams of root of Chinese trichosanthes, Radix Angelicae Sinensis 10 Gram, 10 grams of the root of Dahurain angelica, 8 grams of Radix Glycyrrhizae, 10 grams of Rhizoma Chuanxiong, 10 grams of Radix Astragali, 10 grams of green peel, 10 grams of campanulaceae, 10 grams of Snakegourd Fruit, 10 grams of radix bupleuri, in vain 10 grams of Chinese herbaceous peony, 6 grams of cassia twig, 3 grams of the root of three-nerved spicebush.
3. the preparation method of drug according to claim 1 or claim 2, it includes the following steps:
(One)Stock
(1)The seed of cowherb:It winnows with a dustpan net impurity, sets in pot, taken out, cooled with the when of popping white flower six, seventy percent is fried with slow fire;
(2)Radix Rhapontici seu Radix Echinopsis:Net impurity is picked, unhairing is cleaned, moisturized, and is sliced, is dried;
(3)The stem pith of the rice-paper plant:Impurity is picked, is sliced;
(4)Honeysuckle:Silt is weeded out, net impurity is picked;
(5)Fructus Forsythiae:Net impurity is picked, is rubbed open, discarding stalk is removed;
(6)Radix paeoniae rubra:Crude drug is taken, impurity is removed, size stepping is cleaned, moisturized, shave, dry, weeds out clast;
(7)Moutan bark:Impurity is picked, core is removed, cleans, moisturizes, is sliced, dries;
(8)Tangerine leaf:Net impurity is picked, is dried;
(9)Dandelion:Impurity is picked, soil is cleaned, segment is dried;
(10)Harts horn carbon:A pound piece is taken to be ground into fine powder;
(11)Fructus Liquidambaris:Impurity is removed, cleans, dries;
(12)Great burdock achene:Impurity is picked, spare is weeded out;
(13)Bulbus fritillariae cirrhosae:Impurity is picked, is slightly steeped, is pulled out with water, bored profit is peelled off the heart, dried;
(14)Root of Chinese trichosanthes:Impurity is picked, size block is separated, saturating with bubble about sixty percent, pulls out, and bored profit is cut to uniform humidity inside and outside Piece dries;
(15)Radix Angelicae Sinensis:Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries;
(16)The root of Dahurain angelica:Net impurity is picked, is eluted with water, is impregnated, is pulled out and moisturize, when slightly shining to crust without soapy feeling, then after bored profit, cut Piece is dried;
(17)Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, moisturize slice, dry;
(18)Rhizoma Chuanxiong:Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, and is sliced after bored profit, dry;
(19)Radix Astragali:Net impurity is picked, remaining head and hollow larger root is removed, is soaked in water, pulls out, cut in time after moisturizing Piece dries;
(20)Green peel:Net impurity is picked, is soaked in water, is pulled out, is moisturized, is sliced, dries;
(21)Campanulaceae:Net impurity is picked, removing LU is removed, cleans and pulls out, be sliced, dry after moisturizing;
(22)Snakegourd Fruit:Crude drug is taken, impurity and carpopodium are removed, is cleaned, is flattened, chopping or fritter are dry;
(23)Radix bupleuri:Impurity is picked, residual stem is removed, silt is cleaned, pulls out, is sliced after moisturizing, dries immediately in time;
(24)Radix Paeoniae Alba:Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit to uniform humidity inside and outside, Slice, it is dry;
(25)Cassia twig:It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit;
(26)The root of three-nerved spicebush:Impurity is picked, size bar is separated, it is saturating with bubble, paid attention to changing water according to season, prevent smelly, pulled out in time Slice, weeds out grey bits;
(Two)It prepares
(1)By the seed of cowherb of the weight, Radix Rhapontici seu Radix Echinopsis, the stem pith of the rice-paper plant, honeysuckle, Fructus Forsythiae, radix paeoniae rubra, moutan bark, tangerine leaf, dandelion, deer Angle, Fructus Liquidambaris, great burdock achene, bulbus fritillariae cirrhosae, root of Chinese trichosanthes, Radix Angelicae Sinensis, the root of Dahurain angelica, Radix Glycyrrhizae, Rhizoma Chuanxiong, Radix Astragali, green peel, campanulaceae, Snakegourd Fruit, radix bupleuri, Radix Paeoniae Alba, cassia twig, the root of three-nerved spicebush are put into decocting container, add 8 times of water amount, after impregnating 90 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is poured into container;
(2)The dregs of a decoction of filtering are added into 6 times of amounts of water, are boiled by intense fire, then with being cooked by slow fire 30 minutes, filter to obtain second of decoction liquor;
(3)It decoction liquor will be mixed evenly twice, and be divided into 3 doses and take.
CN201810370162.2A 2018-04-24 2018-04-24 A kind of drug and preparation method thereof for treating acute mastitis Withdrawn CN108272954A (en)

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Application publication date: 20180713