CN108452223A - A kind of drug and preparation method thereof for treating ovarian cyst - Google Patents
A kind of drug and preparation method thereof for treating ovarian cyst Download PDFInfo
- Publication number
- CN108452223A CN108452223A CN201810407150.2A CN201810407150A CN108452223A CN 108452223 A CN108452223 A CN 108452223A CN 201810407150 A CN201810407150 A CN 201810407150A CN 108452223 A CN108452223 A CN 108452223A
- Authority
- CN
- China
- Prior art keywords
- grams
- radix
- impurity
- picked
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003814 drug Substances 0.000 title claims abstract description 35
- 229940079593 drug Drugs 0.000 title claims abstract description 29
- 208000025661 ovarian cyst Diseases 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 241000208671 Campanulaceae Species 0.000 claims abstract description 12
- 240000004980 Rheum officinale Species 0.000 claims abstract description 12
- 235000008081 Rheum officinale Nutrition 0.000 claims abstract description 12
- 241000427159 Achyranthes Species 0.000 claims abstract description 11
- 244000144725 Amygdalus communis Species 0.000 claims abstract description 11
- 235000011437 Amygdalus communis Nutrition 0.000 claims abstract description 11
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 11
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 11
- 241001166194 Geranium wilfordii Species 0.000 claims abstract description 11
- 241000545744 Hirudinea Species 0.000 claims abstract description 11
- 244000197580 Poria cocos Species 0.000 claims abstract description 11
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 11
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 11
- 241000157352 Uncaria Species 0.000 claims abstract description 11
- 235000020224 almond Nutrition 0.000 claims abstract description 11
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 11
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 10
- 238000001816 cooling Methods 0.000 claims abstract description 9
- 239000012535 impurity Substances 0.000 claims description 38
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- 241000196324 Embryophyta Species 0.000 claims description 6
- 238000009835 boiling Methods 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 4
- 230000003020 moisturizing effect Effects 0.000 claims description 4
- 238000009738 saturating Methods 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 3
- BVPWJMCABCPUQY-UHFFFAOYSA-N 4-amino-5-chloro-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl]benzamide Chemical compound COC1=CC(N)=C(Cl)C=C1C(=O)NC1CCN(CC=2C=CC=CC=2)CC1 BVPWJMCABCPUQY-UHFFFAOYSA-N 0.000 claims description 2
- 244000301850 Cupressus sempervirens Species 0.000 claims description 2
- 235000014676 Phragmites communis Nutrition 0.000 claims description 2
- 238000002425 crystallisation Methods 0.000 claims description 2
- 230000008025 crystallization Effects 0.000 claims description 2
- 239000002689 soil Substances 0.000 claims description 2
- 239000007921 spray Substances 0.000 claims description 2
- 240000005809 Prunus persica Species 0.000 claims 1
- 230000003760 hair shine Effects 0.000 claims 1
- 210000004369 blood Anatomy 0.000 abstract description 42
- 239000008280 blood Substances 0.000 abstract description 42
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 12
- 208000026435 phlegm Diseases 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 9
- 229940035676 analgesics Drugs 0.000 abstract description 4
- 239000000730 antalgic agent Substances 0.000 abstract description 4
- 230000006870 function Effects 0.000 description 25
- 210000004185 liver Anatomy 0.000 description 16
- 208000002193 Pain Diseases 0.000 description 15
- 239000000796 flavoring agent Substances 0.000 description 14
- 235000019634 flavors Nutrition 0.000 description 14
- 210000001015 abdomen Anatomy 0.000 description 13
- 235000019640 taste Nutrition 0.000 description 12
- 210000004072 lung Anatomy 0.000 description 11
- 210000002216 heart Anatomy 0.000 description 10
- 210000000952 spleen Anatomy 0.000 description 9
- 206010011224 Cough Diseases 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 208000004998 Abdominal Pain Diseases 0.000 description 7
- 206010007247 Carbuncle Diseases 0.000 description 7
- 206010015037 epilepsy Diseases 0.000 description 7
- 210000002784 stomach Anatomy 0.000 description 7
- 206010037660 Pyrexia Diseases 0.000 description 6
- 235000009508 confectionery Nutrition 0.000 description 6
- 208000035475 disorder Diseases 0.000 description 6
- 208000001848 dysentery Diseases 0.000 description 6
- 208000014674 injury Diseases 0.000 description 6
- 201000000736 Amenorrhea Diseases 0.000 description 5
- 206010001928 Amenorrhoea Diseases 0.000 description 5
- 206010010774 Constipation Diseases 0.000 description 5
- 206010028980 Neoplasm Diseases 0.000 description 5
- 208000025865 Ulcer Diseases 0.000 description 5
- 238000009825 accumulation Methods 0.000 description 5
- 231100000540 amenorrhea Toxicity 0.000 description 5
- 230000006378 damage Effects 0.000 description 5
- 208000002173 dizziness Diseases 0.000 description 5
- 210000003734 kidney Anatomy 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 231100000397 ulcer Toxicity 0.000 description 5
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 210000002429 large intestine Anatomy 0.000 description 4
- 230000027939 micturition Effects 0.000 description 4
- 231100000862 numbness Toxicity 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 208000032843 Hemorrhage Diseases 0.000 description 3
- 208000008454 Hyperhidrosis Diseases 0.000 description 3
- 208000037093 Menstruation Disturbances Diseases 0.000 description 3
- 206010027339 Menstruation irregular Diseases 0.000 description 3
- 206010033128 Ovarian cancer Diseases 0.000 description 3
- 206010061535 Ovarian neoplasm Diseases 0.000 description 3
- 206010033557 Palpitations Diseases 0.000 description 3
- 230000000202 analgesic effect Effects 0.000 description 3
- 235000019658 bitter taste Nutrition 0.000 description 3
- 230000000740 bleeding effect Effects 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 201000004792 malaria Diseases 0.000 description 3
- 230000005906 menstruation Effects 0.000 description 3
- 239000002574 poison Substances 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 230000008736 traumatic injury Effects 0.000 description 3
- 206010010904 Convulsion Diseases 0.000 description 2
- 206010015958 Eye pain Diseases 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 240000005001 Paeonia suffruticosa Species 0.000 description 2
- 235000003889 Paeonia suffruticosa Nutrition 0.000 description 2
- 206010036790 Productive cough Diseases 0.000 description 2
- 206010044565 Tremor Diseases 0.000 description 2
- 206010000269 abscess Diseases 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 201000001881 impotence Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 210000000867 larynx Anatomy 0.000 description 2
- 201000005630 leukorrhea Diseases 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 210000001672 ovary Anatomy 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 208000024794 sputum Diseases 0.000 description 2
- 210000003802 sputum Anatomy 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 206010046901 vaginal discharge Diseases 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010012218 Delirium Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 206010018612 Gonorrhoea Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 208000032844 Hemoperitoneum Diseases 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- 206010061217 Infestation Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 208000031853 Peritoneal haemorrhage Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 206010057071 Rectal tenesmus Diseases 0.000 description 1
- 241000593989 Scardinius erythrophthalmus Species 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- 238000003457 Shi epoxidation reaction Methods 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010046788 Uterine haemorrhage Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 208000011279 abdominal lump Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000001147 anti-toxic effect Effects 0.000 description 1
- 239000000729 antidote Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 208000013219 diaphoresis Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 238000013399 early diagnosis Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000009245 menopause Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 201000005111 ocular hyperemia Diseases 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000000505 pernicious effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 201000010727 rectal prolapse Diseases 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 235000019643 salty taste Nutrition 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 210000004999 sex organ Anatomy 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 208000012271 tenesmus Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/902—Sparganiaceae (Bur-reed family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of drugs and preparation method thereof for treating ovarian cyst, its be disappeared by asafoetide, radix bupleuri, Radix Glycyrrhizae, Radix Angelicae Sinensis, radix paeoniae rubra, campanulaceae, uncaria, geranium wilfordii, peach kernel, almond, orange peel, moutan bark, cassia twig, rheum officinale, leech, awns, Cortex Phellodendri, Radix Paeoniae Alba, Poria cocos, trigone, the root of bidentate achyranthes, fushen, Radix Polygalae are prepared according to a certain weight ratio, drug of the present invention has clearing heat and cooling blood, removing blood stasis and analgesics, eliminating the phlegm apocenosis, with the function of blood dispersing blood stasis, ovarian cyst is quick, good effect for treating, and does not recur.
Description
Technical field
The present invention relates to a kind of drugs and preparation method thereof for treating ovarian cyst, belong to the field of Chinese medicines.
Background technology
Ovarian cyst is to belong to one kind of sensu lato ovarian neoplasm, the various ages can illness, but with 20-50 years old female
Property is the most common.Ovarian neoplasm is female sex organs kinds of tumor, has a variety of different properties and form, i.e.,：Single type is mixed
Mould assembly, side property or bilateral, capsule or substance, benign or malignant, wherein common with capsule, the degree of pernicious change is very high.
Early diagnosis is difficult, and 70 % have belonged to late period when medical, can seldom obtain early treatment, survival rate is hovered always in 20- within 5 years
30 % are to threaten one of women's life most serious malignant tumour.Since western medicine side effect is big, people are to effectively treating
There are great demands for the Chinese medicine of ovarian cyst, up to now, it has not been found that the related report about the present invention.
Invention content
Repeatedly verification of the present inventor according to research and the clinical test of theory of traditional Chinese medical science has finally found effectively treatment ovary
The drug of tumour, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine compositions of effective treatment ovarian cyst.
Another aim of the present invention is to provide the preparation methods of the Chinese medicine composition.
Drug of the present invention be selection asafoetide, radix bupleuri, Radix Glycyrrhizae, Radix Angelicae Sinensis, radix paeoniae rubra, campanulaceae, uncaria, geranium wilfordii, peach kernel, almond,
Orange peel, moutan bark, cassia twig, rheum officinale, leech, awns disappear, Cortex Phellodendri, Radix Paeoniae Alba, Poria cocos, trigone, the root of bidentate achyranthes, fushen, Radix Polygalae are combined system
Standby, make each efficacy of drugs generate synergistic effect these pharmaceutical compositions, so as to effectively treat ovarian cyst.Wherein select
It is to enter liver, spleen, stomach because its is bitter in taste acrid in flavour and warm in nature, there is disperse accumulation, the function , Zhi abdominal mass and lump of desinsection, malnutrition due to parasitic infestation, meat with asafoetide
Product, trusted subordinate's crymodynia, malaria, dysentery.Select radix bupleuri be because its is bitter in taste, it is cool, enter liver, gallbladder channel, have in inducing diaphoresis, it is soothing the liver, rise
The function of sun controls fevers and chills alternate, and fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower profit rectal prolapse, irregular menstruation, under uterus
It hangs down.It is to enter spleen, stomach, lung channel because of its nature and flavor sweet and neutral to select Radix Glycyrrhizae, is had and middle emergency, moistening lung, removing toxic substances, the work(of coordinating the drug actions of a prescription
Energy；Toast is used, and taste deficiency of food, abdominal pain loose stool, overstrain fever, consumptive lung disease cough, palpitaition , Jing Epilepsy are controlled；It is raw to use, abscess of throat is controlled, is digested
Property ulcer, carbuncle subcutaneous ulcer sore, antidote poison and food poisoning.It is to enter the heart, liver, the spleen channel because of its nature and flavor sweet, acrid, warm, have to select Radix Angelicae Sinensis
Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, the function of moisturize laxation control irregular menstruation, and Amenorrhea abdominal pain , Disorder lump in the abdomen knots are poly-, uterine bleeding, headache due to deficiency of blood,
Dizziness, Impotence numbness, intestinal dryness difficulty is just, heavy after dysentery characterized by blood in the stool, ulcer sores, metal-inflicted wound, injury from falling down.Select radix paeoniae rubra be because its is bitter in taste, it is micro-
Cold, return liver warp has clearing heat and cooling blood, the function of removing blood stasis and analgesics to control epidemic heat syndrome and go mad, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, warp
Close dysmenorrhoea , Epilepsy lump in the abdomen abdominal pain, injury from falling down, carbuncle swells sore.It is to put down because of its nature and flavor toil, enter lung, stomach, have out to select campanulaceae
Facilitaing lung gas, the function of eliminating the phlegm apocenosis control exogenous cough, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery abdominal pain.Select uncaria
Be because its is bitter in taste, it is cool, enter liver, the heart channel of Hang-Shaoyin, there is The flat liver of heat-clearing, the function for the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. controls little Jing Epilepsy Chi Zong, adult's blood pressure
It is higher, dizzy, dizzy, married woman's sub- Epilepsy.It is to have wind-dispelling because of its nature and flavor toil to select geranium wilfordii, is invigorated blood circulation, clearing heat and detoxicating work(
Can, treatment of rheumatalgia pain, contraction, ulcer, bruise, enteritis, dysentery.Select peach kernel be because of its sweet and neutral bitter in taste, enter the heart,
Liver, large intestine channel have the blood-breaking row stasis of blood, moisturize the function of sliding warp, controlling through closing , Disorder lumps in the abdomen, and pyreticosis stores blood, blood-arthralgia, malaria, traumatic injury,
Blood stasis and swelling pain, the dry constipation of blood.It is because its is bitter in taste to select almond, and temperature is toxic, enters lung, large intestine channel, there is expelling phlegm and arresting coughing, relievings asthma,
The function of ease constipation controls exogenous cough, and asthma is full, larynx numbness, dry constipation of intestines.It is because its nature and flavor is arduous to select orange peel, and temperature enters spleen, lung
Through having a qi-regulating, in tune, eliminating dampness, the function of resolving sputum controls fullness and oppression of chest and abdomen, and do not feel like eating vomits hiccup, coughing with a lot of sputum.Select tree peony
Skin is worked hard because of its nature and flavor, cool, enters the heart, liver and kidney channel, has heat-clearing, cool blood and blood, the function of dispersing blood stasis to control heat invading xuefen, is sent out
Spot , Jing Epilepsy, spits, is defeated in battle, has blood in stool, and hectic fever due to yin labor heat, Amenorrhea , Disorder lumps in the abdomen, large carbuncle flutters damage.Select cassia twig be because of the pungent sweet, warm of its nature and flavor,
Enter bladder, the heart, lung channel, there is sweating expelling pathogenic factors from muscles and skin, the function of warming meridians and promoting circulation of qi to control exterior syndrome due to wind-cold, shoulder carries on the back podomere ache, obstruction of qi in the chest phlegm and retained fluid, warp
Bi Disorder lumps in the abdomen.It is to enter stomach, large intestine, liver diameter because its is bitter in taste, cold, there is the poison that purges heat to select rheum officinale, breaks stagnant, the function of row hemostasis,
Control real heat constipation, delirious speech is gone mad, dyspepsia feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menopause Bi , lumps in the chest and abdomen, when the hot epidemic disease of row, cruelly
Swelling ophthalmalgia is spitted blood, bleeding from five sense organs or subcutaneous tissue, yang jaundice, oedema, and stranguria with turbid discharge is urinated red, large carbuncle pyogenic infections, furunculosis, burn.It is because of its property to select leech
The salty hardship of taste is put down, toxic, enters liver, bladder warp, there is blood-breaking, and by the stasis of blood, the function of promoting menstruation is controlled and stores Xue , Disorder lumps in the abdomen, accumulation, women's Amenorrhea,
Dry blood is at consumptive disease, injury from falling down, conjunctival congestion with ophthalmalgia, cloudiness.It is to tremble with fear because of its property acrid,bitter and salty taste, enter stomach, large intestine channel, have and rush down to select awns to disappear
Heat is moisturized, the function of softening hard masses, is controlled real heat and is stagnated, and abdominal distention constipation stops phlegm accumulation, and hot eyes is hidden from view, erysipelas, carbuncle swells.Selecting Cortex Phellodendri is
Because its is bitter in taste, trembles with fear, enter lung, stomach, kidney channel, there is nourishing yin and lessening fire, the function of moisturize laxation to control dysphoria with smothery sensation and quench one's thirst, hectic fever due to yin labor heat, lung
Heat cough, dry feces, difficult urination.Select Radix Paeoniae Alba be because of its nature and flavor picric acid, it is cool, enter liver, the spleen channel, there is nourishing blood and liver, delay
The cloudy function of receiving sweat is held back in middle analgesic, controls chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, and irregular menstruation collapses
Leakage, under.It is to put down because of its property slightly sweet flavor, enter the heart, spleen, lung channel, there is eliminating dampness and diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative to select Poria cocos
Function, control difficult urination oedema distending pain, phlegm and retained fluid cough is inverse, the sound of vomiting of vomitting, diarrhea, seminal emission, stranguria with turbid discharge, palpitation with fear, it is forgetful.Select trigone be because
It for its nature and flavor toil, puts down, enters liver, the spleen channel, there is a blood-breaking, promoting the circulation of qi, disperse accumulation, the function of analgesic controls lumps in the chest and abdomen, and qi and blood coagulates band, the heart
Abdomen pain, swollen pain under the side of body, Amenorrhea, postpartum blood stasis abdominal pain, traumatic injury, sore swells are hard.It is because of its nature and flavor sweetness and bitterness to select the root of bidentate achyranthes
Acid is put down, and liver and kidney channel, life scattered blood stasis are entered, and subduing inflammation controls gonorrhoea, hematuria, Amenorrhea , Disorder lumps in the abdomen, difficult labour, placenta retension, the postpartum stasis of blood
Hemoperitoneum pain, larynx numbness, carbuncle swells, traumatic injury are ripe that filling liver kidney, strengthening the bones and muscles is used to control control waist and knee ostalgia, four fertile contractions, Impotence numbness.Select fushen
It is to put down because of its property slightly sweet flavor, enter the heart, the spleen channel, there is calming heart, calms the nerves, the function of Li Shui controls palpitation with fear of having a guilty conscience, forgetful, has a sleepless night, and shies
Epilepsy, difficult urination.It is to enter the heart, kidney channel because its is bitter in taste acrid in flavour and warm in nature to select Radix Polygalae, there is a tranquilize the mind and promote the intelligence, eliminating the phlegm, the function of Xie Yu,
Control palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, ulcer sore swells.
Specific implementation mode
The drug dose of instant component is also to be obtained by plenty of explorations of the inventor, and the dosage of each component is following heavy
All tools have a better effect in amount range：
1-3 grams of asafoetide, 5-15 grams of radix bupleuri, 5-15 grams of Radix Glycyrrhizae, 5-15 grams of Radix Angelicae Sinensis, 10-20 grams of radix paeoniae rubra, 10-20 grams of campanulaceae, uncaria
10-20 grams, 15-25 grams of geranium wilfordii, 5-15 grams of peach kernel, 5-15 grams of almond, 5-15 grams of orange peel, 5-15 grams of moutan bark, cassia twig 5-15
Gram, 5-15 grams of rheum officinale, 5-15 grams of leech, awns disappears 5-15 grams, 15-20 grams of Cortex Phellodendri, 5-15 grams of Radix Paeoniae Alba, 14-18 grams of Poria cocos, trigone 5-
15 grams, 10-20 grams of the root of bidentate achyranthes, 5-15 grams of fushen, 5-15 grams of Radix Polygalae.
Preferably：
2 grams of asafoetide, 10 grams of radix bupleuri, 10 grams of Radix Glycyrrhizae, 10 grams of Radix Angelicae Sinensis, 15 grams of radix paeoniae rubra, 15 grams of campanulaceae, 15 grams of uncaria, 20 grams of geranium wilfordii,
10 grams of peach kernel, 10 grams of almond, 10 grams of orange peel, 10 grams of moutan bark, 10 grams of cassia twig, 10 grams of rheum officinale, 10 grams of leech, awns disappear 10 grams, yellow
15 grams of cypress, 10 grams of Radix Paeoniae Alba, 16 grams of Poria cocos, 10 grams of trigone, 15 grams of the root of bidentate achyranthes, 10 grams of fushen, 10 grams of Radix Polygalae.
The preparation method of drug of the present invention is as follows
One, it stocks up
1, asafoetide：Impurity is picked, fritter is hacked into；
2, radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulls out, is sliced, dries in time after moisturizing；
3, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, moisturize, be sliced, dry；
4, Radix Angelicae Sinensis：Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries；
5, radix paeoniae rubra：Crude drug is taken, impurity is removed, size stepping is cleaned, moisturized, shave, dry, weeds out clast；
6, campanulaceae：Net impurity is picked, removing LU is removed, cleans and pulls out, be sliced, dry after moisturizing；
7, uncaria：Old stalk, impurity are picked, cleans, dries；
8, geranium wilfordii：Impurity is picked, undesirable root is removed, is eluted with water, pulls out, segment is dried；
9, peach kernel：Hard shell impurity is removed, sets in boiling water pot and boils to crust microcreping, pull out, is immersed in cold water, kind of a skin is removed in stranding, dries,
It winnows with a dustpan net；
10, almond：Net impurity is picked, sets in boiling water and slightly boils, skin microcreping of waiting rises and pulls out, soaks in cold water, sloughs kind of a skin, dry, and winnows with a dustpan net；
11, orange peel：Soil is brushed away, picks net impurity, sprays clear water, chopping or slice after bored profit dry；
12, moutan bark：Impurity is picked, core is removed, cleans, moisturizes, is sliced, dries；
13, cassia twig：It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit；
14, rheum officinale：Net impurity is picked, size stepping is stewed to moisten to uniform humidity inside and outside, is sliced or is cut into small pieces, dries；
15, leech：It cleans, bored soft, segment is dried；
16, awns disappears：It takes the awns naturally produced to disappear, after boiling-off, filtering, cooling, the crystallization on upper layer is taken to disappear for awns；
17, Cortex Phellodendri：Impurity is picked, is eluted with water, is pulled out, is moisturized, slice or chopping are dried；
18, Radix Paeoniae Alba：Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit to uniform humidity inside and outside,
Slice, it is dry；
19, Poria cocos：It is soaked in water, cleans and pull out, after bored, slice dries；
20, trigone：Net impurity is picked, is soaked in water, pulls out and moisturizes, is sliced, dries；
21, the root of bidentate achyranthes：Impurity is picked, is cleaned, is softened, reed, segment is gone to dry；
22, fushen：Crude drug is taken, impurity is removed, cleans, moisturizes, the sheet or block of square is cut into, dries in the shade；
23, Radix Polygalae：Impurity is picked, segment weeds out grey bits.
Two, it prepares
1, by the asafoetide of the weight, radix bupleuri, Radix Glycyrrhizae, Radix Angelicae Sinensis, radix paeoniae rubra, campanulaceae, uncaria, geranium wilfordii, peach kernel, almond, orange peel, male
The root bark of tree peony, cassia twig, rheum officinale, leech, awns disappear, Cortex Phellodendri, Radix Paeoniae Alba, Poria cocos, trigone, the root of bidentate achyranthes, fushen, Radix Polygalae are put into decocting container, adds
6 times of water amount, after impregnating 90 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, by the
One time decoction liquor is poured into container；
2, the dregs of a decoction of filtering are added into 4 times of amounts of water, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；
3, it decoction liquor will be mixed evenly twice, and be divided into 2 doses and take.
Radix paeoniae rubra has clearing heat and cooling blood in prescription, and the function of removing blood stasis and analgesics is monarch drug in a prescription；Campanulaceae has open the inhibited lung-energy, the work(of eliminating the phlegm apocenosis
Energy；It is ministerial drug that moutan bark, which has the function of clearing heat and cooling blood and blood dispersing blood stasis, the two, and three taste medicines play clearing heat and cooling blood jointly, and the scattered stasis of blood is stopped
Bitterly, open the inhibited lung-energy, the effect of eliminating the phlegm apocenosis and blood dispersing blood stasis, treatment ovarian cyst effect is comprehensive, and with clearing heat and cooling blood, the scattered stasis of blood is stopped
Bitterly, it can effect a permanent cure based on eliminating the phlegm apocenosis and blood dispersing blood stasis, rheum officinale has the poison that purges heat, and breaks and stagnates, and the function of row hemostasis is adjutant, and trigone has
Blood-breaking, promoting the circulation of qi, disperse accumulation, the function of analgesic are to make medicine, and all medicines are to take stopgap measures with being left.
Drug of the present invention has clearing heat and cooling blood, removing blood stasis and analgesics, the function of eliminating the phlegm apocenosis and blood dispersing blood stasis, for treating ovary
Tumour, short treating period, quick, non-relapse after healing.
Carry out the advantageous effect of the present invention is further explained the drug below by way of test example, these test examples include this hair
The animal toxicity test report of bright drug and clinical observation on the therapeutic effect data.
The animal toxicity test of [test example 1] drug of the present invention is reported：
Rabbit 30, male and female dual-purpose, 2.0-2.5kg of weight is taken to be divided to two groups, every group 15, one of which is tested for overdose
Group, another group is normal amount test group.Super quantity group is 20ml/kg, normal amount 10ml/kg, and administering mode gives for administration by gavage
Medicine even served 7 days twice daily, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and drug is without bad
Toxic side effect.
The clinical observation on the therapeutic effect of [test example 2] drug of the present invention
1, general information
Accept ovarian cyst out-patient totally 41 for medical treatment.
2, diagnostic criteria
The existing underbelly pain of the main multilist of symptom, underbelly discomfort, leucorrhea increasing, leukorrhea color Huang, leukorrhea peculiar smell, menstruation are not normal, and
And usually there are one solid and painless lumps, sometimes sexual intercourse, and pain can occur in underbelly.When tumour influences hormone secretion,
It is likely to occur Irregular vagina bleeding or the symptoms such as chaeta increases.If torsion of pedicle occurs for ovarian cyst, there is serious abdomen
Pain abdominal distension, expiratory dyspnea, appetite reduction, nausea and fever etc..Larger tumour nearby can cause to oppress to bladder, cause frequent micturition
And dysuria.Especially when these symptoms are more frequent than more serious, bleeding and occur simultaneously, women suffers from the possibility of ovarian cyst
Property higher, the harm of lesion malignant ovary cancer is with regard to bigger.
3, therapy
Above-mentioned medicament is selected, is taken to patient, each taking 1 dose, early daily, evening respectively takes 1 time, 15 days as a treatment course, continuously
It takes 4 course for the treatment of.
4, efficacy assessment standard
It is effective：Ovarian cyst symptom disappears, and constitution restores normal, recovery from illness；
It improves：The symptoms were significantly improved for ovarian cyst, and underbelly pain relief, menstruation and appetite are gradually restored；
In vain：Improvement standard person is not achieved.
5, treatment results（It see the table below）
In above-mentioned treatment, with drug therapy ovarian cyst patient 41 of the present invention, as a result effective 35, obvious effective rate 85.4%,
It improves 4, improvement rate 9.7%, invalid 2, total effective rate 95.1%.
Claims (3)
1. a kind of drug for treating ovarian cyst, it is characterised in that：It is made of the bulk pharmaceutical chemicals in following weight range：
1-3 grams of asafoetide, 5-15 grams of radix bupleuri, 5-15 grams of Radix Glycyrrhizae, 5-15 grams of Radix Angelicae Sinensis, 10-20 grams of radix paeoniae rubra, 10-20 grams of campanulaceae, uncaria
10-20 grams, 15-25 grams of geranium wilfordii, 5-15 grams of peach kernel, 5-15 grams of almond, 5-15 grams of orange peel, 5-15 grams of moutan bark, cassia twig 5-15
Gram, 5-15 grams of rheum officinale, 5-15 grams of leech, awns disappears 5-15 grams, 15-20 grams of Cortex Phellodendri, 5-15 grams of Radix Paeoniae Alba, 14-18 grams of Poria cocos, trigone 5-
15 grams, 10-20 grams of the root of bidentate achyranthes, 5-15 grams of fushen, 5-15 grams of Radix Polygalae.
2. drug according to claim 1, wherein the dosage of each bulk pharmaceutical chemicals is：
2 grams of asafoetide, 10 grams of radix bupleuri, 10 grams of Radix Glycyrrhizae, 10 grams of Radix Angelicae Sinensis, 15 grams of radix paeoniae rubra, 15 grams of campanulaceae, 15 grams of uncaria, 20 grams of geranium wilfordii,
10 grams of peach kernel, 10 grams of almond, 10 grams of orange peel, 10 grams of moutan bark, 10 grams of cassia twig, 10 grams of rheum officinale, 10 grams of leech, awns disappear 10 grams, yellow
15 grams of cypress, 10 grams of Radix Paeoniae Alba, 16 grams of Poria cocos, 10 grams of trigone, 15 grams of the root of bidentate achyranthes, 10 grams of fushen, 10 grams of Radix Polygalae.
3. the preparation method of drug according to claim 1 or claim 2, it includes the following steps：
（One）Stock
（1）Asafoetide：Impurity is picked, fritter is hacked into；
（2）Radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulls out, is sliced, dries in time after moisturizing；
（3）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, moisturize, be sliced, dry；
（4）Radix Angelicae Sinensis：Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries；
（5）Radix paeoniae rubra：Crude drug is taken, impurity is removed, size stepping is cleaned, moisturized, shave, dry, weeds out clast；
（6）Campanulaceae：Net impurity is picked, removing LU is removed, cleans and pulls out, be sliced, dry after moisturizing；
（7）Uncaria：Old stalk, impurity are picked, cleans, dries；
（8）Geranium wilfordii：Impurity is picked, undesirable root is removed, is eluted with water, pulls out, segment is dried；
（9）Peach kernel：Hard shell impurity is removed, sets in boiling water pot and boils to crust microcreping, pull out, is immersed in cold water, kind of a skin is removed in stranding, shines
It is dry, it winnows with a dustpan net；
（10）Almond：Net impurity is picked, sets in boiling water and slightly boils, skin microcreping of waiting rises and pulls out, soaks in cold water, sloughs kind of a skin, dry, winnow with a dustpan
Only；
（11）Orange peel：Soil is brushed away, picks net impurity, sprays clear water, chopping or slice after bored profit dry；
（12）Moutan bark：Impurity is picked, core is removed, cleans, moisturizes, is sliced, dries；
（13）Cassia twig：It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit；
（14）Rheum officinale：Net impurity is picked, size stepping is stewed to moisten to uniform humidity inside and outside, is sliced or is cut into small pieces, dries；
（15）Leech：It cleans, bored soft, segment is dried；
（16）Awns disappears：It takes the awns naturally produced to disappear, after boiling-off, filtering, cooling, the crystallization on upper layer is taken to disappear for awns；
（17）Cortex Phellodendri：Impurity is picked, is eluted with water, is pulled out, is moisturized, slice or chopping are dried；
（18）Radix Paeoniae Alba：Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit to uniform humidity inside and outside,
Slice, it is dry；
（19）Poria cocos：It is soaked in water, cleans and pull out, after bored, slice dries；
（20）Trigone：Net impurity is picked, is soaked in water, pulls out and moisturizes, is sliced, dries；
（21）The root of bidentate achyranthes：Impurity is picked, is cleaned, is softened, reed, segment is gone to dry；
（22）Fushen：Crude drug is taken, impurity is removed, cleans, moisturizes, the sheet or block of square is cut into, dries in the shade；
（23）Radix Polygalae：Impurity is picked, segment weeds out grey bits；
（Two）It prepares
（1）By the asafoetide of the weight, radix bupleuri, Radix Glycyrrhizae, Radix Angelicae Sinensis, radix paeoniae rubra, campanulaceae, uncaria, geranium wilfordii, peach kernel, almond, orange peel,
Moutan bark, cassia twig, rheum officinale, leech, awns disappear, Cortex Phellodendri, Radix Paeoniae Alba, Poria cocos, trigone, the root of bidentate achyranthes, fushen, Radix Polygalae are put into decocting container,
Add 6 times of amounts of water, after impregnating 90 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, it will
First time decoction liquor is poured into container；
（2）The dregs of a decoction of filtering are added into 4 times of amounts of water, are boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；
（3）It decoction liquor will be mixed evenly twice, and be divided into 2 doses and take.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810407150.2A CN108452223A (en) | 2018-05-02 | 2018-05-02 | A kind of drug and preparation method thereof for treating ovarian cyst |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810407150.2A CN108452223A (en) | 2018-05-02 | 2018-05-02 | A kind of drug and preparation method thereof for treating ovarian cyst |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108452223A true CN108452223A (en) | 2018-08-28 |
Family
ID=63214411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810407150.2A Withdrawn CN108452223A (en) | 2018-05-02 | 2018-05-02 | A kind of drug and preparation method thereof for treating ovarian cyst |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108452223A (en) |
-
2018
- 2018-05-02 CN CN201810407150.2A patent/CN108452223A/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103735969B (en) | A kind of medicine for the treatment of consumptive lung disease and preparation method thereof | |
| CN106943507A (en) | It is a kind of to treat medicine of senile macular degeneration and preparation method thereof | |
| CN108452223A (en) | A kind of drug and preparation method thereof for treating ovarian cyst | |
| CN108379520A (en) | A kind of drug and preparation method thereof for treating gastric cancer | |
| CN108355111A (en) | A kind of drug and preparation method thereof for treating cervix cancer | |
| CN108524888A (en) | A kind of drug and preparation method thereof for treating insomnia | |
| CN108371703A (en) | A kind of drug and preparation method thereof for treating cervical carcinoma | |
| CN108653681A (en) | A kind of drug and preparation method thereof for treating senile dementia | |
| CN108379518A (en) | A kind of drug and preparation method thereof for treating oophoroma | |
| CN103751752B (en) | A kind of medicine for the treatment of dysentery and preparation method thereof | |
| CN102988883B (en) | Medicament for treating pneumonia and preparation method of medicament | |
| CN102657727B (en) | Medicine for treating colonitis and preparation method thereof | |
| CN105435034A (en) | Medicine for treating hemoptysis and preparation method thereof | |
| CN108272954A (en) | A kind of drug and preparation method thereof for treating acute mastitis | |
| CN108420947A (en) | A kind of drug and preparation method thereof for treating breast cancer | |
| CN108379516A (en) | A kind of drug and preparation method thereof for treating headstroke | |
| CN108524867A (en) | A kind of drug and preparation method thereof for treating liver cancer | |
| CN108355094A (en) | A kind of drug and preparation method thereof for treating kidney | |
| CN108452053A (en) | A kind of drug and preparation method thereof for treating nettle rash | |
| CN108295200A (en) | A kind of drug and preparation method thereof for treating appendicitis | |
| CN108310326A (en) | A kind of drug and preparation method thereof for treating mammary swelling during menstruation | |
| CN108371707A (en) | A kind of drug and preparation method thereof for treating carcinoma of urinary bladder | |
| CN108815453A (en) | A kind of drug and preparation method thereof for treating ulcer of the cornea | |
| CN109045197A (en) | A kind of drug and preparation method thereof for treating sclerotitis | |
| CN108310235A (en) | A kind of drug and preparation method thereof of therapeutic community's property retinitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180828 |