CN108743738A - A kind of Granule-rhinitis and preparation method thereof - Google Patents
A kind of Granule-rhinitis and preparation method thereof Download PDFInfo
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- CN108743738A CN108743738A CN201810543982.7A CN201810543982A CN108743738A CN 108743738 A CN108743738 A CN 108743738A CN 201810543982 A CN201810543982 A CN 201810543982A CN 108743738 A CN108743738 A CN 108743738A
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Abstract
The invention discloses a kind of Granule-rhinitis and preparation method thereof, belong to Chinese medicine manufacturing field.A kind of Granule-rhinitis, it is characterised in that be made of the Chinese herbal medicine of following parts by weight：8~20 parts of honeysuckle, 8~20 parts of wild chrysanthemum, 8~20 parts of dandelion, 8~20 parts of Chinese violet, 10~25 parts of the achene of Siberian cocklebur, 5~18 parts of radix semiaquilegiae, 5~18 parts of the root of Dahurain angelica, 5~18 parts of the flower bud of lily magnolia, 5~18 parts of peppermint, 5~18 parts of Rhizoma Chuanxiong, 5~18 parts of radix paeoniae rubra, 5~18 parts of radix scutellariae, 5~18 parts of Radix Glycyrrhizae, 5~18 parts of field pennycress.The Granule-rhinitis of the present invention, it is not only easy to carry, drink conveniently, safety, mouthfeel is suitable, also has the function of antibacterial anti-inflammatory, control allergy, improves body's immunity, it is most important that it is edible that Granule-rhinitis of the invention is suitable for the crowds such as diabetes, three high crowds, pregnant woman, child.
Description
Technical field
The present invention relates to Chinese medicine manufacturing field, more particularly to a kind of Granule-rhinitis and preparation method thereof.
Background technology
Rhinitis is a kind of very common disease in life, and nose is key except lung, and the generation of rhinitis is related by heresy with lung channel,
Its urgency person often because of wind-cold affecting lung, or experiences wind-heat or even Lung Qi obstraction, and clear key is done in visitor's heresy, leads to nasal congestion.Ailment said due to cold or exposure solution
Afterwards, hot and suffocating unclear, it makes as turbid tears.Rhinitis Symptoms mainly have nasal obstruction, runny nose, sneezing, smell decline, have a headache, is dizzy, anaphylaxis
Rhinitis, chronic nasosinusitis show as head heavy feeling more；Also loss of appetite, easily tired, failure of memory and insomnia etc..Chronic nose
Scorching harm：The frequent easy catching a cold of patient, sneezing, the clear nasal mucus of stream, itch, unsmooth, nosebleed of ventilating, drying, incrustation, hair are smelt,
Neurasthenia, headache, giddy etc. cause abscess of throat, cardiac arrhythmia etc..It is brought greatly to rhinitis chronic patient work, life
Pain, rhinitis chronic is if treatment is not in time, or even can convert nasopharyngeal carcinoma.
The harm of allergic rhinitis：It is extraneous can effectively to resist filtering as first of barrier of human body respiration for nasal cavity
Virus, the breaking-out of anaphylaxis rhinitis make its miopragia, and then germ enters internal each organ, causes lesion.It can cause nose
Sinusitis, bronchial asthma, secretory otitis media, anaphylaxis sphagitis, nasal polyp, nosebleed, the complication such as asphyxia of feeling suffocated.
Currently, many rhinitis drugs on the market are all only palliative, it is typically only capable to alleviate symptom at that time, not
Treatment is played, once climate change, environmental change, touch anaphylactogen just and start to feel bad, and city is used for a long time
Drug on face can also have certain drug resistance.And tablet, medicament on the market etc. all contains sugared part mostly, and it is also toxic
Side effect even more " makes the matter worse " especially for pregnant woman, child, diabetes, the three high patients etc. with rhinitis, and rhinitis is violated
, the drug for treating rhinitis containing sugared part has been eaten, symptom is alleviated, but blood glucose rise can be made, really suffer untold misery.
Invention content
It is an object of the invention to：In view of the above problems, a kind of Granule-rhinitis is provided, is not only disappeared with antibacterial
Scorching, control allergy, the effect for improving body's immunity, can make patients with rhinitis fundamentally obtain medical treatment, uneasy to recur,
Most importantly Granule-rhinitis of the invention adds steviol glycoside, play the role of hypoglycemic, reducing blood lipid, adjust blood glucose etc., it fits
It is edible for diabetes, three high crowds.The electuary of the present invention not only reconstitutes conveniently, and mouthfeel is suitable, absorbs soon, and nontoxic pair is made
With.The present invention also provides a kind of production methods of Granule-rhinitis.
The technical solution adopted by the present invention is as follows：
A kind of Granule-rhinitis, it is characterised in that be made of the Chinese herbal medicine of following parts by weight：8~20 parts of honeysuckle, wild chrysanthemum 8~20
Part, 8~20 parts of dandelion, 8~20 parts of Chinese violet, 10~25 parts of the achene of Siberian cocklebur, 5~18 parts of radix semiaquilegiae, 5~18 parts of the root of Dahurain angelica, the flower bud of lily magnolia 5~
18 parts, 5~18 parts of peppermint, 5~18 parts of Rhizoma Chuanxiong, 5~18 parts of radix paeoniae rubra, 5~18 parts of radix scutellariae, 5~18 parts of Radix Glycyrrhizae, field pennycress 5~18
Part.
Preferably, 10~15 parts of honeysuckle, 10~15 parts of wild chrysanthemum, 10~15 parts of dandelion, 10~15 parts of Chinese violet, Siberian cocklebur
12~18 parts of son, 8~12 parts of radix semiaquilegiae, 8~12 parts of the root of Dahurain angelica, 8~12 parts of the flower bud of lily magnolia, 8~12 parts of peppermint, 8~12 parts of Rhizoma Chuanxiong, radix paeoniae rubra
8~12 parts, 8~12 parts of radix scutellariae, 8~12 parts of Radix Glycyrrhizae, 10~15 parts of field pennycress.
Preferably, further include auxiliary material, the auxiliary material is Icing Sugar, beta-cyclodextrin, inorganic salts, wetting agent.
Preferably, the Icing Sugar is mixed by steviol glycoside and starch, mixed proportion 1：0.2.
Preferably, the wetting agent is purified water or ethyl alcohol.
Preferably, inorganic salts can be calcium carbonate or medicinal calcium carbonate.
A kind of preparation method of Granule-rhinitis, includes the following steps：
（1）It is dandelion, Chinese violet, the achene of Siberian cocklebur, radix semiaquilegiae, the root of Dahurain angelica, the flower bud of lily magnolia, peppermint, Rhizoma Chuanxiong, red by the honeysuckle, wild chrysanthemum
The Chinese herbal medicine that Chinese herbaceous peony, radix scutellariae, Radix Glycyrrhizae, field pennycress mix by weight, which is put into 30 DEG C~40 DEG C of warm water, impregnates 30min, will
Chinese herbal medicine draining takes out, and is put into container and adds water to cook secondary, the ratio of herbal medicine and water is 1：3, heating time 1.5h~2h are obtained
Decocting liquid merges decocting liquid twice, and filtering concentrates the filtrate to the clear cream of defined relative density, adds the wetting agent of equivalent, keeps it heavy
It forms sediment, after taking supernatant recycling ethyl alcohol and concentrating, adds 1.5 times of water, stir, stand 7h~10h, take supernatant concentration to proportion
Wetting agent and inorganic salts are added in the clear cream of 1.38-1.40, qinghuo reagent, Icing Sugar, beta-cyclodextrin, are uniformly mixed, logical with fashion of extrusion
14~22 mesh screens are crossed, dry wet particle is made；
（2）By step（1）Filter residue be sequentially placed into drying unit and dried, crush, fine drug powder obtained with screen filtration, be added
Icing Sugar, beta-cyclodextrin, wetting agent and inorganic salts are uniformly mixed, and with fashion of extrusion by 14~22 mesh screens, are made wet dry
Grain；
（3）By step（1）And step（2）Made dry wet particle is uniformly mixed, and is dried, is cooled down in time, is sieved, is made
Particle is uniform；
（4）Selection is not easy to breathe freely, the packaging material of moisture-inhibiting, by step（3）The particle of gained is carried out using automatic granular packaging machine
Packing, often packet particle is 10g, dry storage.
Preferably, the filtrate is concentrated into the clear cream of defined relative density, is the heat survey proportion at 80 DEG C~90 DEG C
It is 1.30~1.35.
Preferably, the drying temperature is 60 DEG C~80 DEG C, the clear cream, the mixed proportion of Icing Sugar, beta-cyclodextrin
It is 1：3：1.
Preferably, the drying temperature is 60 DEG C~80 DEG C, and the degree of drying of particle controls water content below 2%.
Honeysuckle：Honeysuckle is just extensive and famous with its medical value since ancient times.Its effect is mainly clearing heat and detoxicating,
Cure mainly warm disease heating, toxic-heat and blood stasis, ulcer serious case of furuncle etc..Honeysuckle contains the pharmacological components such as chlorogenic acid, cyanidenon glycosides, right
The various pathogens such as hemolytic streptococcus, Staphylococcus aureus and infection of the upper respiratory tract Causative virus etc. have stronger restraint,
It in addition can also strengthen immunity, Robust speaker feature, protect liver, antitumor, anti-inflammatory, antipyretic, hemostasis（Blood coagulation）, inhibit intestinal absorption cholesterol
Deng.Honeysuckle is cold in nature, sweet in flavor, enters lung, the heart, stomach, has effects that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treats wind, cures mainly under turgor
The diseases such as disease, warm disease heating, heat toxin large carbuncle and tumour.It is for dizziness, thirst, sweating and boring, enteritis, bacillary dysentery, fiber crops
Rash, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer boils, erysipelas, parotitis, suppuration
The illnesss such as property tonsillitis have certain curative effect.
Wild chrysanthemum：Wild chrysanthemum is " broad-spectrum antibiotic " in Chinese herbal medicine, to most dermatophytes, staphylococcus aureus,
Shigella dysenteriae, Pseudomonas aeruginosa and influenza virus etc. all have a strong inhibitory effect.Wild chrysanthemum is the cephaloid of feverfew mother chrysanthemum
Sequence, main component are yejuhua lactone, chrysanthemol, flavonoid glycoside etc., cold nature, tool dispelling wind and heat from the body, subdhing swelling and detoxicating, it is anti-infective,
Antiviral effect.Chinese medicine thinks that wild chrysanthemum is cool in nature, there is dispelling wind and heat, removing toxicity for detumescence, brain nourishing and eyesight improving and other effects, can treat
Treat that coronary heart disease, hypertension, anemopyretic cold, pneumonia, rhinitis, bronchitis, abscess of throat, hot eyes be fuzzy, adenolymphitis, carbuncle furuncle malignant boil
The diseases such as poison, eczema, pruitus, aphtha, erysipelas.Antibacterial, antivirus action, to staphylococcus aureus, Escherichia coli, diphtheria
Bacillus, shigella dysenteriae, Pseudomonas aeruginosa, proteus have different degrees of inhibiting effect.With heat-clearing, anti-inflammatory properties；Antioxygen
Change, improve immunity of organisms, has apparent scavenging effect to ultra-oxygen anion free radical.
Dandelion：Dandelion herb be rich in vitamin A, vitamin C and potassium, also contain iron, calcium, vitamin B2, vitamin B1, magnesium,
Vitamin B6, folic acid and copper.Specific constituent content is mainly moisture, every 60 grams of dandelion herb leaves moisture content 86%, protein
1.6 grams, 5.3 grams of carbohydrate, there are about 108.8 kilojoules for heat.In dandelion plant containing taraxol, taraxacin,
A variety of health-nutrition ingredients such as choline, organic acid, synanthrin.Nature and flavor are sweet, slight bitter, tremble with fear.Return liver, stomach.There are diuresis, laxative, removing jaundice
Subcutaneous ulcer, cholagogic and other effects.Heat toxin, carbuncle swells, sore, internal carbuncle, red eye, swell pain, damp and hot, jaundice, the puckery pain of dribbling urination, furuncle swelling toxin are controlled,
Acute mastitis, scrofula, toothache, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.Control acute mastitis, adenolymphitis, scrofula
Scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urine
Road feel dye etc..Antibacterial action has inhibiting effect to staphylococcus aureus, typhoid bacillus；It is antimycotic, to microsporon audouini
Trichophyton schoenleini, Trichophyton rubrum etc. have inhibiting effect.Antitumor, antitumor action is by immune similar to lentinan
What mechanism was realized.
Chinese violet：Chinese violet is a kind of costly Chinese herbal medicine, will not generate harm to organs such as stomach, will not cause pair substantially
Effect.It is usually taken after fresh Chinese violet is smashed to pieces and uses, the primary efficacy of Chinese violet is clearing heat and detoxicating and cool blood is purged heat, for treatment
The disease caused by blood-head, effect highly significant.The drug can fundamentally reduce internal internal heat, make the functions such as blood circulation
Restore normal, plays the perfect effect of internal and external application.The symptoms such as suppurate in addition, Chinese violet can also be used to treatment, play detoxification and
The effect of suppuration detumescence.
The achene of Siberian cocklebur：The achene of Siberian cocklebur is the fruit of the maturation zone involucre of feverfew Siberian cocklebur, belongs to Chinese medicine warm-pungent diaphoretic drug, toxic；
It can expel pathogenic wind from the body surface, declare clearing the nasal passage, damp dispelling and pain relieving.For treating anemofrigid headache, nasosinusitis runny nose, rubella itch etc., the achene of Siberian cocklebur is controlled
Treating rhinitis has unique curative effect.
Radix semiaquilegiae：It is clearing heat and detoxicating；Dispersing swelling and dissipating binds；Promoting diuresis for stranguria.It is frightened to cure mainly children's heat；Epilepsy；Carbuncle swells；Furunculosis；Acute mastitis；Scrofula
Scrofula；Skin is itched sore；Red eye, swell pain；Pharyngalgia；Snakebite and bugbite；Heat gonorrhea；Sand drenches.
The root of Dahurain angelica：Wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving.For having a headache, having a toothache, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, carbuncle
Subcutaneous ulcer sore, pruitus.Relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, clearing the nasal passage, eliminating dampness stops band, detumescence and apocenosis.Control headache, pain in the supra-orbital bone, tooth
Bitterly, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin itchy, mange.《Detailed outline》：Control nasosinusitis, nosebleed epistaxis,
Dentalgia, pain in the supra-orbital bone, big intestines wind is secret, bleeding urine, and the dizzy fortune of married woman's blood wind, regurgitation spits food；Solve arsenic poison, snakebite, knife arrow metal-inflicted wound.
《Japan hanako materia medica》：It controls the hot eyes triangular mass of mucous membrane growing from the inner corner of the eye and tire patching leakage slides, break place blood, mend new blood, acute mastitis, carbuncle on the back, scrofula, intestines wind, hemorrhoid complicated by anal fistula,
Apocenosis, desolation, mange relieve pain myogenic, go face Shao- defect scars.《Haigoushen》：Control trusted subordinate's blood shouting pain, exorcising, main woman's metrorrhagia and
It vomits inverse, improving eyesight, only lacrimation treat married woman and drip blood, waist abdominal pain；Purulence can be lost.In the excited medulla oblongata respiratory center of root of Dahurain angelica element energy, vasomotion
Pivot and vagus nerve can make breathing enhancing, blood pressure rising, pulse slack-off.
The flower bud of lily magnolia：It is acrid in flavour and warm in nature.It attaches to the lung and stomach meridians.Cold-dispelling, clearing the nasal passage.For anemofrigid headache, nasal obstruction, nasosinusitis, turbid nasal discharge.The flower bud of lily magnolia has
The effect of dispersing wind and cold, can be used for controlling rhinitis, blood pressure lowering；The flower bud of lily magnolia can control anemofrigid cold.The pungent scattered temperature of the product is logical, energy expelling cold, eliminating,
Declare clearing the nasal passage.It is caught cold with controlling, lung key closing, fever with aversion to cold, have a headache nasal obstruction person, with the root of Dahurain angelica with the use of energy expelling cold, eliminating.
With peppermint, honeysuckle cooperation can control anemopyretic cold and the headache person that has a stuffy nose, and can enhance clearing the nasal passage, relieve heat heresy power.Flos Magnoliae Liliflorae
Nasosinusitis can be controlled.The product pungent-warm dissipates, awakening consciousness, is reached in property, external enwergy removing cold and wind perverse trend, and interior energy, which rises, reaches the clear gas of lung stomach,
Kind clearing the nasal passage, to control the key medicine of nasosinusitis headache, nasal congestion；The achene of Siberian cocklebur, inclined wind-heat person, mostly with the dispelling winds such as peppermint, radix scutellariae heat, clear
Lung heat medicine is the same as use.With wild chrysanthemum cooperation can clearing heat-fire antidotal therapy lung stomach it is hot and suffocating hair be nose sore person.
Peppermint：Fragrant odour, can sensible, antipruritic, analgesia, the kind evacuation part of the body cavity above the diaphragm housing the heart and lungs wind-heat of work(, refresh oneself, throat are for having a headache
Hot eyes, abscess of throat.It can control in wind-heat and attack with chrysanthemum cooperation, headache and hot eyes；Coordinate with licorice, stops up Sheng, throat with wind-heat is controlled
Swelling and pain；In addition there is antivirus action, have inhibiting effect to viral ECHO11 plants；There are anti-irritant, antitussive action：Menthol resists
Stimulation causes tracheae to generate new secretion, and the mucus of stiff is made to be easy to be discharged, therefore has phlegm-dispelling functions；Bactericidal effect, it is thin
Lotus brain has very strong bactericidal effect, the bacteriostasis of d- menthol ratio 1- menthols strong.
Rhizoma Chuanxiong：There are blood-activating and qi-promoting, wind-expelling pain-stopping.For pacifying nerve, positive head wind headache, abdominal mass abdominal pain, chest side of body shouting pain falls
Swelling and pain are flutterred, are had a headache, the effect of arthralgia pain due to rheumatism.The pungent fragrant kind liter of Rhizoma Chuanxiong, energy uplink head mountain peak top has wind-expelling pain-stopping effect, to control
Head wind headache key medicine can have a headache with the cooperations such as the root of Dahurain angelica, chrysanthemum caused by rhinitis, flu.
Radix paeoniae rubra：Bitter, cold nature.Return liver warp.Have the function of clearing heat and cooling blood, removing blood stasis and analgesics.It is chiefly used in warm disease heat and enters blood
The hot bleeding of body divided, red eye, swell pain, carbuncle sore tumefacting virus.Its property acid is held back cloudy soft, has yin-nourishing, the row stasis of blood, analgesic, cool blood, detumescence.
Radix scutellariae：There are heat-clearing and damp-drying drug, cool blood tocolysis, detoxicating functions.Cure mainly the warm heat disease, infection of the upper respiratory tract, cough with lung heat, wet
The diseases such as hot jaundice, pneumonia, dysentery, hemoptysis, hot eyes, fetal irritability, hypertension, carbuncle swells furuncle sore.There is the work(of tocolysis with teasel root, uses
Control fetal irritability.Radix scutellariae pharmacological property is cold and cool, clearing heat-fire, tocolysis, with the fetal irritability controlled caused by tire heat.Teasel root pharmacological property tepor is mended
Liver kidney, tocolysis, with the fetal irritability controlled caused by kidney deficiency and liver.
Radix Glycyrrhizae：It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, burnout is weary
Power, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, pain swell sore, alleviate drug toxicity, strong.
Field pennycress：For acute appendicitis, lung carbuncle high fever, cough vomiting of pus and blood, heat toxin sore malignant boil, boil pain is swollen, chest and abdomen pain, appendicitis,
Enteritis, dysentery, postpartum abdominal pain, dysmenorrhoea.The nutritive value of field pennycress is relatively high, containing protein, sugar, food fiber, calcium, phosphorus, zinc,
The mineral elements such as copper, iron, manganese and vitamin B1, vitamin B2, vitamin C, carrotene, niacin etc..In addition, also containing courage
The chemical substances such as alkali, tartaric acid, bitter principle.The heat-clearing of field pennycress energy, cool blood, removing toxic substances.There is certain curative effect to various inflammation.
Steviol glycoside：Steviol glycoside has blood pressure lowering, strengthening body, controls the medical values such as chaff urine disease, weight-reducing, steviol glycoside master
There are treatment diabetes, control blood glucose, reduces blood pressure, is antitumor, anti diar rhea, improving immunity, the effects that boosting metabolism,
There is fine effect to obesity controlling disease, adjusting hydrochloric acid in gastric juice, recovery neural fatigue, also has notable treatment to heart disease, pediatric saprodontia etc.
Effect, it is most important that it can eliminate the side effect of sucrose.Steviol glycoside analog derivative also has antihypertensive, blood glucose, antitumor,
Improve diarrhea and improves the immunity of the human body.Steviol glycoside, which is added, in electuary of the present invention can make the inclined sweet tea of mouthfeel, cover medium-height grass
The bitter taste of medicine itself, allows patient preferably to receive.
Usage and dosage：3 times a day, it 1~2 wraps every time, half an hour warm water is taken after meal.Every 10 days as a treatment course.Child,
Pregnant woman's dose halves.
Beneficial effects of the present invention：
（1）The essence of Chinese medicine is passed on, a kind of prescription pharmacology of Granule-rhinitis of the invention is：Clear the nasal passage removes secretion, resists
Bacterium anti-inflammatory, inhibition and killing bacterium, antiallergy, facilitaing lung apocenosis, blood pressure lowering, adjust blood glucose at virus, improve immunity of organisms.With
Facilitaing lung apocenosis is honeysuckle flower, wild chrysanthemum, dandelion, Chinese violet, radix semiaquilegiae, radix scutellariae, the achene of Siberian cocklebur, the flower bud of lily magnolia of main ingredient, and experimental study shows
They play the role of inhibition or killing to various bacteria, virus；To have the achene of Siberian cocklebur of antianaphylactic effect, sweet to antihistaminicum
Grass is adjuvant；The radix paeoniae rubra relieved pain, river medicine are become silted up as adjuvant using promoting blood circulation row；Using peppermint as adjuvant, can clear the nasal passage, remove secretion
's.Experiments have shown that having inhibiting effect to a variety of gram-Negative bacillus；There is antibacterial anti-inflammatory, control allergy to improve for full side
The effect of body's immunity.Achieve the purpose that treatment with this.
（2）Inorganic salts are mainly used for absorbing the liquid in prescription.Icing Sugar, beta-cyclodextrin are mainly used for increasing the weight of tablet
Amount and volume, wetting agent are that one kind does not have sticking liquid, effect to be moistening tablet materials and induce the viscosity of material in itself.
Particle made from this method passes through moistened surface, has granular mass good, and appearance looks elegant, wearability are compared with strong, compact property is good
The advantages of.
（3）Electuary made of Chinese herbal medicine can use mixing in water for oral taking, not only maintain the characteristic of decoction, but also decoction is overcome to decoct temporarily,
The shortcomings that being easy to go mouldy, and the bitter taste of drug can be covered, drug effect absorbs faster compared with solid pharmaceutical preparation, and better efficacy, safety is made without pair
With for the pregnant woman for having rhinitis and good news, the formula also have cool blood tocolysis in addition to that can treat rhinitis, and detoxify work(
Effect, therefore, formula adult, child, pregnant woman, diabetes, three high crowds are drinkable, will not both be made because of solid pharmaceutical preparation
Raw material cause hepar damnification, and the advantages that easy to carry, transport, use.
（4）Steviol glycoside is mixed with starch can play moisture-proof, anti-bonding, anti-mildew effect.
（5）In the preparation method of the Granule-rhinitis of the present invention, supernatant is obtained with the method for water boiling, auxiliary material, system is added
It at particle, is crushed again after the filter residue of Chinese herbal medicine is dried, auxiliary material is added, particle is made, be then again uniformly mixed all particles
It is dried, it is therefore an objective to which Chinese herbal medicine is very expensive, and filter residue of Chinese herbal medicine itself yet has good drug effect, the side with water boiling
Particle mixing is made in method, Chinese medicinal herbs can be made adequately to be used, and the Granule-rhinitis of the present invention can also played
Better therapeutic effect fundamentally improves the physical function of patient, improves immunity of organisms, and antibacterial anti-inflammatory, control are abnormal anti-
It answers, to achieve the purpose that treating both manifestation and root cause of disease.
Specific implementation mode
Embodiment 1
A kind of Granule-rhinitis, it is characterised in that be made of the Chinese herbal medicine of following parts by weight：8 parts of honeysuckle, 8 parts of wild chrysanthemum, Pu Gong
8 parts of English, 8 parts of Chinese violet, 10 parts of the achene of Siberian cocklebur, 5 parts of radix semiaquilegiae, 5 parts of the root of Dahurain angelica, 5 parts of the flower bud of lily magnolia, 5 parts of peppermint, 5 parts of Rhizoma Chuanxiong, 5 parts of radix paeoniae rubra, Huang
5 parts of a kind of reed mentioned in ancient books, 5 parts of Radix Glycyrrhizae, 5 parts of field pennycress.
Further include auxiliary material, the auxiliary material is Icing Sugar, beta-cyclodextrin, inorganic salts, wetting agent.
The Icing Sugar is mixed by steviol glycoside and starch, mixed proportion 1：0.2.
The wetting agent is purified water or ethyl alcohol.
The inorganic salts can be calcium carbonate or medicinal calcium carbonate.
Embodiment 2
A kind of Granule-rhinitis, it is characterised in that be made of the Chinese herbal medicine of following parts by weight：12 parts of honeysuckle, 12 parts of wild chrysanthemum, Pu
12 parts of public English, 12 parts of Chinese violet, 115 parts of the achene of Siberian cocklebur, 12 parts of radix semiaquilegiae, 12 parts of the root of Dahurain angelica, 12 parts of the flower bud of lily magnolia, 12 parts of peppermint, 12 parts of Rhizoma Chuanxiong,
12 parts of radix paeoniae rubra, 12 parts of radix scutellariae, 12 parts of Radix Glycyrrhizae, 12 parts of field pennycress.
Further include auxiliary material, the auxiliary material is Icing Sugar, beta-cyclodextrin, inorganic salts, wetting agent.
The Icing Sugar is mixed by steviol glycoside and starch, mixed proportion 1：0.2.
The wetting agent is purified water or ethyl alcohol.
The inorganic salts can be calcium carbonate or medicinal calcium carbonate.
Embodiment 3
A kind of Granule-rhinitis, it is characterised in that be made of the Chinese herbal medicine of following parts by weight：20 parts of honeysuckle, 20 parts of wild chrysanthemum, Pu
20 parts of public English, 20 parts of Chinese violet, 25 parts of the achene of Siberian cocklebur, 18 parts of radix semiaquilegiae, 18 parts of the root of Dahurain angelica, 18 parts of the flower bud of lily magnolia, 18 parts of peppermint, 18 parts of Rhizoma Chuanxiong,
18 parts of radix paeoniae rubra, 18 parts of radix scutellariae, 18 parts of Radix Glycyrrhizae, 18 parts of field pennycress.
Further include auxiliary material, the auxiliary material is Icing Sugar, beta-cyclodextrin, inorganic salts, wetting agent.
The Icing Sugar is mixed by steviol glycoside and starch, mixed proportion 1：0.2.
The wetting agent is purified water or ethyl alcohol.
The inorganic salts can be calcium carbonate or medicinal calcium carbonate.
The preparation method that above-described embodiment 1 to 3 is all made of, includes the following steps：
A kind of preparation method of Granule-rhinitis is provided, is included the following steps：
（1）It is dandelion, Chinese violet, the achene of Siberian cocklebur, radix semiaquilegiae, the root of Dahurain angelica, the flower bud of lily magnolia, peppermint, Rhizoma Chuanxiong, red by the honeysuckle, wild chrysanthemum
The Chinese herbal medicine that Chinese herbaceous peony, radix scutellariae, Radix Glycyrrhizae, field pennycress mix by weight, which is put into 30 DEG C~40 DEG C of warm water, impregnates 30min, will
Chinese herbal medicine draining takes out, and is put into container and adds water to cook secondary, the ratio of herbal medicine and water is 1：3, heating time 1.5h~2h are obtained
Decocting liquid merges decocting liquid twice, and filtering concentrates the filtrate to the clear cream of defined relative density, adds the wetting agent of equivalent, keeps it heavy
It forms sediment, after taking supernatant recycling ethyl alcohol and concentrating, adds 1.5 times of water, stir, stand 7h~10h, take supernatant concentration to proportion
Wetting agent and inorganic salts are added in the clear cream of 1.38-1.40, qinghuo reagent, Icing Sugar, beta-cyclodextrin, are uniformly mixed, logical with fashion of extrusion
14~22 mesh screens are crossed, dry wet particle is made；
（2）By step（1）Filter residue be sequentially placed into drying unit and dried, crush, fine drug powder obtained with screen filtration, be added
Icing Sugar, beta-cyclodextrin, wetting agent and inorganic salts are uniformly mixed, and with fashion of extrusion by 14~22 mesh screens, are made wet dry
Grain；
（3）By step（1）And step（2）Made dry wet particle is uniformly mixed, and is dried, is cooled down in time, is sieved, is made
Particle is uniform；
（4）Selection is not easy to breathe freely, the packaging material of moisture-inhibiting, by step（3）The particle of gained is carried out using automatic granular packaging machine
Packing, often packet particle is 10g, dry storage.
The quality examination of granule：
Typical case：
1, Chen, man, 40 years old.Readme is often had a headache over 10 years, rhinorrhea, amount it is more, nasal obstruction, anosmia, to the wind or cold then
Purulence tears abruptly increase, exacerbation of symptoms go through several doctors, successively use antibiotic, hormone, antiallergic, and rhinitis tablet and Naphazoline etc., which are deceived, imitates.
Examine and see turbid nasal discharge, if yellow thick purulence, taste is smelly, schneiderian membrane chronic congestion, and swelling is plump, in, hypertrophic inferior turbinate, middle nasal meatus and olfactory cleft
There are purulence object, x ray photograph prompt：Double mucous membrane of maxillary sinus thicken and have empyema.Diagnosis：Chronic purulent nasosinusitis uses top then,
Symptom falls sharply after 5 courses for the treatment of, and tears flavescence is thick, and 5 courses for the treatment of of following the service, all diseases, which are known, removes, and to consolidate curative effect, then takes 5 doses, complete more without multiple
Hair.
2, Mrs Yang, Guangxi Guigang personage, 4 years old child's allergic rhinitis, usually nasal mucus is especially more, and child also has nose
The case where hyperonychia and adenoids, especially sleep nasal obstruction is severe at night, and child is also easy to catch a cold.Because of allergia nose
Inflammation can not effect a radical cure, so child's medication is all right, break out not medication, and Rhinitis Symptoms again and again make Mrs Yang very worried.Successively
Using antibiotic, antiallergic, rhinitis tablet and Naphazoline, salt wash nose method etc. and deceive effect.Diagnosis：Allergic rhinitis uses top then,
Symptom falls sharply after 2 courses for the treatment of, and tears flavescence is thick, and 3 courses for the treatment of of following the service, all diseases, which are known, removes, and to consolidate curative effect, then takes 5 doses, complete more without multiple
Hair.
This Chongji for Treatment chronic nasosinusitis 98, allergic rhinitis, 68, wherein recovery from illness 83；It is effective 76, total effective
Rate 95.8%.
Claims (10)
1. a kind of Granule-rhinitis, it is characterised in that be made of the Chinese herbal medicine of following parts by weight：8~20 parts of honeysuckle, wild chrysanthemum 8~
20 parts, 8~20 parts of dandelion, 8~20 parts of Chinese violet, 10~25 parts of the achene of Siberian cocklebur, 5~18 parts of radix semiaquilegiae, 5~18 parts of the root of Dahurain angelica, the flower bud of lily magnolia 5
~18 parts, 5~18 parts of peppermint, 5~18 parts of Rhizoma Chuanxiong, 5~18 parts of radix paeoniae rubra, 5~18 parts of radix scutellariae, 5~18 parts of Radix Glycyrrhizae, field pennycress 5~
18 parts.
2. a kind of Granule-rhinitis according to claim 1, it is characterised in that be made of the Chinese herbal medicine of following parts by weight：Gold and silver
Spend 10~15 parts, 10~15 parts of wild chrysanthemum, 10~15 parts of dandelion, 10~15 parts of Chinese violet, 12~18 parts of the achene of Siberian cocklebur, radix semiaquilegiae 8
~12 parts, 8~12 parts of the root of Dahurain angelica, 8~12 parts of the flower bud of lily magnolia, 8~12 parts of peppermint, 8~12 parts of Rhizoma Chuanxiong, 8~12 parts of radix paeoniae rubra, radix scutellariae 8~12
Part, 8~12 parts of Radix Glycyrrhizae, 10~15 parts of field pennycress.
3. a kind of Granule-rhinitis according to claim 1 or 2, which is characterized in that further include auxiliary material, the auxiliary material is sugar
Powder, beta-cyclodextrin, inorganic salts, wetting agent.
4. a kind of Granule-rhinitis according to claim 3, which is characterized in that the Icing Sugar is by steviol glycoside and starch
It mixes, mixed proportion 1：0.2.
5. a kind of Granule-rhinitis according to claim 3, which is characterized in that the wetting agent is purified water or ethyl alcohol.
6. a kind of Granule-rhinitis according to claim 3, which is characterized in that inorganic salts can be calcium carbonate or medicinal carbonic acid
Calcium.
7. according to a kind of preparation method of Granule-rhinitis of claim 1 to 6, include the following steps：
（1）It is dandelion, Chinese violet, the achene of Siberian cocklebur, radix semiaquilegiae, the root of Dahurain angelica, the flower bud of lily magnolia, peppermint, Rhizoma Chuanxiong, red by the honeysuckle, wild chrysanthemum
The Chinese herbal medicine that Chinese herbaceous peony, radix scutellariae, Radix Glycyrrhizae, field pennycress mix by weight, which is put into 30 DEG C~40 DEG C of warm water, impregnates 30min, will
Chinese herbal medicine draining takes out, and is put into container and adds water to cook secondary, the ratio of herbal medicine and water is 1：3, heating time 1.5h~2h are obtained
Decocting liquid merges decocting liquid twice, and filtering concentrates the filtrate to the clear cream of defined relative density, adds the wetting agent of equivalent, keeps it heavy
It forms sediment, after taking supernatant recycling ethyl alcohol and concentrating, adds 1.5 times of water, stir, stand 7h~10h, take supernatant concentration to proportion
Wetting agent and inorganic salts are added in the clear cream of 1.38-1.40, qinghuo reagent, Icing Sugar, beta-cyclodextrin, are uniformly mixed, logical with fashion of extrusion
14~22 mesh screens are crossed, dry wet particle is made；
（2）By step（1）Filter residue be sequentially placed into drying unit and dried, crush, fine drug powder obtained with screen filtration, be added
Icing Sugar, beta-cyclodextrin, wetting agent and inorganic salts are uniformly mixed, and with fashion of extrusion by 14~22 mesh screens, are made wet dry
Grain；
（3）By step（1）And step（2）Made dry wet particle is uniformly mixed, and is dried, is cooled down in time, is sieved, is made
Particle is uniform；
（4）Selection is not easy to breathe freely, the packaging material of moisture-inhibiting, by step（3）The particle of gained is carried out using automatic granular packaging machine
Packing, often packet particle is 10g, dry storage.
8. a kind of preparation method of Granule-rhinitis according to claim 7, it is characterised in that：Step（1）Described in filtrate it is dense
The clear cream of relative density as defined in being reduced to is that survey proportion in 80 DEG C~90 DEG C of heat be 1.30~1.35.
9. a kind of preparation method of Granule-rhinitis according to claim 7, it is characterised in that：Step（2）Described in drying temperature
Degree be 60 DEG C~80 DEG C, the clear cream, Icing Sugar, beta-cyclodextrin mixed proportion be 1：3：1.
10. a kind of preparation method of Granule-rhinitis according to claim 7, it is characterised in that：Step（3）The drying temperature
It it is 60 DEG C~80 DEG C, the degree of drying of particle controls water content below 2%.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116115673A (en) * | 2023-04-20 | 2023-05-16 | 吉林省寰宇济民科技有限公司 | Traditional Chinese medicine formula for clearing heat and freeing nose and preparation process |
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2018
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116115673A (en) * | 2023-04-20 | 2023-05-16 | 吉林省寰宇济民科技有限公司 | Traditional Chinese medicine formula for clearing heat and freeing nose and preparation process |
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