CN108700565B - 血液制备和图谱分析 - Google Patents

血液制备和图谱分析 Download PDF

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Publication number
CN108700565B
CN108700565B CN201680071446.0A CN201680071446A CN108700565B CN 108700565 B CN108700565 B CN 108700565B CN 201680071446 A CN201680071446 A CN 201680071446A CN 108700565 B CN108700565 B CN 108700565B
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proteins
red blood
blood cells
sample
blood
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CN108700565A (zh
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伊丽莎白·卡斯滕
本·赫伯特
艾伦·利德尔
卡梅伦·希尔
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Sangui Bio Pty Ltd
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Sangui Bio Pty Ltd
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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CN201680071446.0A 2015-10-07 2016-10-06 血液制备和图谱分析 Active CN108700565B (zh)

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AU2015904075A AU2015904075A0 (en) 2015-10-07 Blood preparation and profiling
AU2015904075 2015-10-07
PCT/AU2016/000341 WO2017059477A1 (en) 2015-10-07 2016-10-06 Blood preparation and profiling

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EP (2) EP4009047A1 (enExample)
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Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3009369A1 (en) 2015-12-22 2017-06-29 Sangui Bio Pty. Ltd Therapeutic methods using erythrocytes
WO2018112500A1 (en) * 2016-12-20 2018-06-28 Sangui Bio Pty. Ltd Blood profiling with protease inhibitors
CN108715833B (zh) * 2018-06-01 2021-09-14 天晴干细胞股份有限公司 一种负载血小板裂解液的微球制备方法
US20240352423A1 (en) * 2021-03-10 2024-10-24 Terasaki Institute For Biomedical Innovation Methods and systems of producing products such as animal derived products
CN114081899A (zh) * 2021-11-02 2022-02-25 四川大学华西医院 一种富白细胞富血小板血浆的制备方法
US20250085283A1 (en) 2022-03-23 2025-03-13 Teijin Limited Method for quantifying nicotinamide adenine dinucleotide (nad+) or nicotinamide mononucleotide (nmn), and kit and filter paper for performing the method
WO2024010763A1 (en) * 2022-07-07 2024-01-11 Russell Biotech, Inc. Preparation of platelet free mononuclear cells

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4931276A (en) 1987-10-30 1990-06-05 Franco Robert S Method for introducing desired agents into red blood cells
US5858358A (en) 1992-04-07 1999-01-12 The United States Of America As Represented By The Secretary Of The Navy Methods for selectively stimulating proliferation of T cells
WO1992005801A1 (en) 1990-10-04 1992-04-16 University Of Virginia Alumni Patents Foundation Primate erythrocyte bound monoclonal antibody heteropolymers
ES2167391T3 (es) * 1994-09-16 2002-05-16 Merck Patent Gmbh Inmunoconjugados ii.
US5763280A (en) * 1997-01-21 1998-06-09 Coulter International Corp. Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis
FR2778851B1 (fr) 1998-05-19 2002-07-26 Aetsrn Composition a base d'inhibiteurs de cysteine-proteases pour retarder la senescence, l'autodestruction et l'hemolyse des erythrocytes
US8431117B2 (en) 1999-08-30 2013-04-30 David S Terman Sickled erythrocytes with anti-tumor agents induce tumor vaso-occlusion and tumoricidal effects
AU2001272670A1 (en) 2000-07-24 2002-02-05 Gendel Limited Polypeptide delivery II-2
PT1495328E (pt) 2002-04-16 2014-09-09 Vlaams Interuniv Inst Biotech Um marcador para medir cirrose hepática
US7501286B2 (en) 2002-08-14 2009-03-10 President And Fellows Of Harvard College Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry
US7276382B2 (en) * 2003-10-02 2007-10-02 Noboru Horiguchi Blood testing method
GB0325483D0 (en) 2003-10-31 2003-12-03 Plasmacute As Assay
US20080095749A1 (en) 2004-03-22 2008-04-24 Sudeepta Aggarwal Mesenchymal stem cells and uses therefor
US7378054B2 (en) 2004-04-16 2008-05-27 Savvipharm Inc Specimen collecting, processing and analytical assembly
US7803523B2 (en) * 2004-08-27 2010-09-28 University Health Network Whole blood preparation for cytometric analysis of cell signaling pathways
US20060166223A1 (en) 2005-01-26 2006-07-27 Reed Michael W DNA purification and analysis on nanoengineered surfaces
WO2006123253A2 (en) 2005-03-29 2006-11-23 Inverness Medical Switzerland Gmbh Device and method of monitoring a patient
US20100184049A1 (en) 2007-04-27 2010-07-22 Steve Goodison Glycoprotein Profiling of Bladder Cancer
FR2919804B1 (fr) 2007-08-08 2010-08-27 Erytech Pharma Composition et vaccin therapeutique anti-tumoral
US8530182B2 (en) 2007-12-05 2013-09-10 Centers For Disease Control And Prevention Viral protein quantification process and vaccine quality control therewith
US20110245092A1 (en) 2008-03-04 2011-10-06 John Bilello Diagnosing and monitoring depression disorders based on multiple serum biomarker panels
KR20210003301A (ko) 2008-05-06 2021-01-11 아스텔라스 인스티튜트 포 리제너러티브 메디슨 다능성 줄기세포로부터 유도된 탈핵 적혈구계 세포를 생산하는 방법
EP2442641A4 (en) 2009-06-16 2016-03-09 Univ Columbia METHOD FOR REDUCING SIDE EFFECTS OF THE TRANSFUSION OF AGED RED BLOOD CELLS
JP6162359B2 (ja) * 2009-06-30 2017-07-12 株式会社カネカ 血液成分の分離システム、分離材
EP2464966A1 (en) 2009-08-13 2012-06-20 Basf Se Means and methods for diagnosingthyroid disorders
US20130202625A1 (en) 2010-01-21 2013-08-08 The Regents Of The University Of Californa Use of human erythrocytes for prevention and treatment of cancer dissemination and growth
SG183195A1 (en) 2010-02-08 2012-09-27 Piramal Imaging Sa F18-tyrosine derivatives for imaging bone metastases
WO2011127056A2 (en) 2010-04-05 2011-10-13 The Uab Research Foundation Biomarkers for assessing exposure to ionizing radiation and absorbed dose
SG195180A1 (en) 2011-05-31 2013-12-30 Singapore Health Serv Pte Ltd Method for detecting disease biomarkers
GB201116767D0 (en) 2011-09-28 2011-11-09 St George S Hospital Medical School Treatment for mitrochondrial neurogastrointestinal encephalomyopathy
CN104394884A (zh) 2012-03-21 2015-03-04 爱瑞泰克药物公司 用于治疗急性髓细胞白血病(aml)的药剂
HU230341B1 (hu) 2012-04-20 2016-02-29 Advancell Diagnosztika Kft. A vörösvérsejt-membrán kvantitatív biomarkerei
EP2872154B1 (en) 2012-07-11 2017-05-31 Sangamo BioSciences, Inc. Methods and compositions for delivery of biologics
EP2994117B1 (en) 2013-05-10 2023-06-07 EryDel S.p.A. Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes
JP6383920B2 (ja) * 2013-09-11 2018-09-05 有限会社ピコデバイス パーキンソン病の判定基準とする方法
CN106255884B (zh) * 2013-10-04 2019-01-11 赛尔爱迪尔私人有限公司 用于细胞治疗的生物标志物
KR101845588B1 (ko) 2014-04-07 2018-04-05 한양대학교 산학협력단 적혈구계 세포의 인 비트로 확장
BR122021024421B1 (pt) 2015-05-18 2022-05-03 Hemanext Inc Usos de um produto de sangue total armazenado reduzido de oxigênio com plaquetas
CA3009369A1 (en) 2015-12-22 2017-06-29 Sangui Bio Pty. Ltd Therapeutic methods using erythrocytes
WO2018112500A1 (en) 2016-12-20 2018-06-28 Sangui Bio Pty. Ltd Blood profiling with protease inhibitors

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