CN108697800A - 用于膀胱癌的光动力疗法（pdt）的方法 - Google Patents

用于膀胱癌的光动力疗法（pdt）的方法 Download PDF

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Publication number
CN108697800A
CN108697800A CN201680079638.6A CN201680079638A CN108697800A CN 108697800 A CN108697800 A CN 108697800A CN 201680079638 A CN201680079638 A CN 201680079638A CN 108697800 A CN108697800 A CN 108697800A
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CN
China
Prior art keywords
bladder
composition
light
blue light
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201680079638.6A
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English (en)
Chinese (zh)
Inventor
K·赫斯特达尔
A·戈达尔
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Photocure ASA
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Photocure ASA
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Publication date
Application filed by Photocure ASA filed Critical Photocure ASA
Priority to CN202411499253.8A priority Critical patent/CN119345612A/zh
Publication of CN108697800A publication Critical patent/CN108697800A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A61N5/0603—Apparatus for use inside the body for treatment of body cavities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/307—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the urinary organs, e.g. urethroscopes, cystoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A61N5/0603—Apparatus for use inside the body for treatment of body cavities
    • A61N2005/061—Bladder and/or urethra
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A61N2005/0663—Coloured light

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radiation-Therapy Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201680079638.6A 2015-12-17 2016-12-19 用于膀胱癌的光动力疗法（pdt）的方法 Pending CN108697800A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202411499253.8A CN119345612A (zh) 2015-12-17 2016-12-19 用于膀胱癌的光动力疗法（pdt）的方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15200938 2015-12-17
EP15200938.7 2015-12-17
PCT/EP2016/081809 WO2017103285A1 (en) 2015-12-17 2016-12-19 Method of photodynamic therapy (pdt) for bladder cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202411499253.8A Division CN119345612A (zh) 2015-12-17 2016-12-19 用于膀胱癌的光动力疗法（pdt）的方法

Publications (1)

Publication Number Publication Date
CN108697800A true CN108697800A (zh) 2018-10-23

Family

ID=55066354

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201680079638.6A Pending CN108697800A (zh) 2015-12-17 2016-12-19 用于膀胱癌的光动力疗法（pdt）的方法
CN202411499253.8A Pending CN119345612A (zh) 2015-12-17 2016-12-19 用于膀胱癌的光动力疗法（pdt）的方法

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CN202411499253.8A Pending CN119345612A (zh) 2015-12-17 2016-12-19 用于膀胱癌的光动力疗法（pdt）的方法

Country Status (18)

Country Link
US (2) US11235168B2 (enExample)
EP (1) EP3389716B1 (enExample)
JP (1) JP6995755B2 (enExample)
KR (1) KR102787192B1 (enExample)
CN (2) CN108697800A (enExample)
AU (1) AU2016372575B2 (enExample)
BR (1) BR112018011965A2 (enExample)
CA (1) CA3008552C (enExample)
CL (1) CL2018001612A1 (enExample)
DK (1) DK3389716T3 (enExample)
ES (1) ES2910034T3 (enExample)
IL (1) IL259925B (enExample)
MX (1) MX385912B (enExample)
PL (1) PL3389716T3 (enExample)
RU (1) RU2745194C2 (enExample)
SG (1) SG11201805000RA (enExample)
WO (1) WO2017103285A1 (enExample)
ZA (1) ZA201804530B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110420326A (zh) * 2019-09-17 2019-11-08 上海复旦张江生物医药股份有限公司 一种多替泊芬的应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201805000RA (en) * 2015-12-17 2018-07-30 Photocure Asa Method of photodynamic therapy (pdt) for bladder cancer
JP7769015B2 (ja) * 2021-08-17 2025-11-12 ボストン サイエンティフィック サイムド，インコーポレイテッド 光活性剤を活性化するためのカテーテルシステム及びカテーテル
WO2024184417A1 (en) 2023-03-07 2024-09-12 Photocure Asa Therapy for bladder cancer

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050031541A1 (en) * 1995-03-10 2005-02-10 Gierskcky Karl E. Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CN101896203A (zh) * 2007-12-12 2010-11-24 光治疗Asa公司 固体形式的5-氨基酮戊酸和衍生物在光动力治疗和诊断中的应用
CN101891639A (zh) * 2009-05-20 2010-11-24 上海先导化学有限公司 一种制备5-氨基酮戊酸盐酸盐的方法
CN102802612A (zh) * 2009-06-11 2012-11-28 光治疗Asa公司 含有5-氨基酮戊酸的固态组合物
CN104244804A (zh) * 2011-12-19 2014-12-24 丹麦科技大学 用于内窥镜应用的照明系统
CN104661994A (zh) * 2012-08-03 2015-05-27 光治疗Asa公司 化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2157424T3 (es) 1995-03-10 2001-08-16 Photocure Asa Esteres de acido 5-aminolevulinico como agentes fotosensibilizantes en fotoquimioterapia.
US20050003154A1 (en) * 2002-12-13 2005-01-06 White Gary L. Laminated building panels having preselected colors
GB0406917D0 (en) 2004-03-26 2004-04-28 Photocure Asa Compounds
GB0700580D0 (en) 2007-01-11 2007-02-21 Photocure Asa Use
SI2440199T1 (sl) 2009-06-11 2016-05-31 Photocure Asa Poltrdni sestavki in farmacevtski proizvodi
RU2448745C2 (ru) * 2010-05-31 2012-04-27 Олег Феликсович Каган Способ лечения поверхностного рака мочевого пузыря
GB201221123D0 (en) * 2012-11-23 2013-01-09 Photocure As Device for photodynamic treatment
SG11201805000RA (en) * 2015-12-17 2018-07-30 Photocure Asa Method of photodynamic therapy (pdt) for bladder cancer

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050031541A1 (en) * 1995-03-10 2005-02-10 Gierskcky Karl E. Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CN101896203A (zh) * 2007-12-12 2010-11-24 光治疗Asa公司 固体形式的5-氨基酮戊酸和衍生物在光动力治疗和诊断中的应用
CN101891639A (zh) * 2009-05-20 2010-11-24 上海先导化学有限公司 一种制备5-氨基酮戊酸盐酸盐的方法
CN102802612A (zh) * 2009-06-11 2012-11-28 光治疗Asa公司 含有5-氨基酮戊酸的固态组合物
CN104244804A (zh) * 2011-12-19 2014-12-24 丹麦科技大学 用于内窥镜应用的照明系统
CN104661994A (zh) * 2012-08-03 2015-05-27 光治疗Asa公司 化合物

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AURÉLIE FRANÇOIS,ET AL.: "How to Avoid Local Side Effects of Bladder Photodynamic Therapy: Impact of the Fluence Rate", 《THE JOURNAL OF UROLOGY》 *
LINDA HELANDER,ET AL.: "Red versus blue light illumination in hexyl 5-aminolevulinate photodynamic therapy: the influence of light color and irradiance on the treatment outcome in vitro", 《JOURNAL OF BIOMEDICAL OPTICS》 *
M. J. BADER,ET AL.: "Photodynamic Therapy of Bladder Cancer -A Phase I Study Using Hexaminolevulinate (HAL)", 《UROLOGIC ONCOLOGY: SEMINARS AND ORIGINAL INVESTIGATIONS》 *
YORAM SALOMON,ET AL.: "EPPM-1 Abstracts", 《PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110420326A (zh) * 2019-09-17 2019-11-08 上海复旦张江生物医药股份有限公司 一种多替泊芬的应用

Also Published As

Publication number Publication date
IL259925B (en) 2022-04-01
JP2019501161A (ja) 2019-01-17
AU2016372575A1 (en) 2018-07-12
US20220152411A1 (en) 2022-05-19
AU2016372575B2 (en) 2022-12-08
CA3008552A1 (en) 2017-06-22
NZ743697A (en) 2024-10-25
MX385912B (es) 2025-03-18
IL259925A (en) 2018-07-31
KR20180094986A (ko) 2018-08-24
RU2018123834A3 (enExample) 2020-04-13
JP6995755B2 (ja) 2022-01-17
US11980772B2 (en) 2024-05-14
CA3008552C (en) 2024-01-02
ZA201804530B (en) 2019-09-25
DK3389716T3 (da) 2022-04-11
PL3389716T3 (pl) 2022-06-20
US11235168B2 (en) 2022-02-01
CL2018001612A1 (es) 2019-01-11
WO2017103285A1 (en) 2017-06-22
CN119345612A (zh) 2025-01-24
BR112018011965A2 (pt) 2018-12-04
SG11201805000RA (en) 2018-07-30
EP3389716B1 (en) 2022-03-23
RU2018123834A (ru) 2020-01-17
ES2910034T3 (es) 2022-05-11
EP3389716A1 (en) 2018-10-24
RU2745194C2 (ru) 2021-03-22
KR102787192B1 (ko) 2025-03-25
US20190022404A1 (en) 2019-01-24

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